Synonym: CELE_H06I04.5, H06I04.5
Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
| Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
|---|---|---|---|---|---|---|---|---|---|
| WSN | Domain of unknown function | 1-58 | 4.1e-23 | 71.1 | Pfam-A | 10-67 (69) | alignment | ||
Range on Protein: 1-58
Range on HMM: 10-67/69.0
MQSLARLTNGISLEIGLIDGSIPSDDAIAELLHMGPVKLQELISMDTDAASKAITDLG
....||.||||.|. |||.||||.||.|||||..|...|..|...|.| ... ...|
lsiiaRvtngIyLqaglingsipiddviaELLnigssslsqllkidvdklkeklnkls
|
|||||||||
| RhoGEF | RhoGEF domain | 142-253 | 8.2e-06 | 12.2 | Pfam-A | 65-176 (180) | alignment | ||
Range on Protein: 142-253
Range on HMM: 65-176/180.0
QKGDTIDSITANFPRlYRDFN-KTENYAISFENVLSSLKLLDSIKN-MSLFLEPVYQeSAFRKELNLSTLTSVIYQALNQFSEQLQTIRKYVSNTKASES
.. .....|. | ..| ..| |...|. || | . .. .. ||. . . | ..|.|..| .. | | .. |. . |. ..... ..
kekkdaqkigdvflk.leeflkvYseYisnfdkalkllkelskknskfkkflkeaee.spesskldLeslLikPvqRlprYplLLkellkatpeshpdye
DLKYIQRLINSLNS
.|. .. |....|
alekaleaikevas
|
|||||||||
| 0051299 | (Phosphotyrosine protein) phosphatases II | 758-1046 | 2.8e-49 | 163.5 | In-house | 8-283 (288) | alignment | ||
Range on Protein: 758-1046
Range on HMM: 8-283/288.0
DHSVKAIQYQMKENKTLLQEWLKSVYRALRTiGETSVTNYDDNISERRHSMYICEPSTMAVLEG----FKNPFINANVMMF--GKIEWIMAQGPMDgtek
.. .|.... .. ..|.|.| . ... | . ...|.... |.. |.| ... .. .| . .|||. . . | ..|..|||..
eellklvlkllangltglleefeellsllpd.ltlsaallpenleknRysdilpydhsRVkLsvldgvegsdYinAsyidgynlkrkfIatqgPlp....
kkdetdkpkrSTCEKHWALIEQHNVAICVQLCGFVEGEDKKCASYYSDkvGGVLRFRNYSLKTIDIKTdlaeftdKKDFTLYTVEITNYR-KNKGEQKKT
.|.|..| .. ..|| . | |...|| . .||| |... ||.| . ... ....... ..|.|..|.|.||.. .......|
..........ntvedFWrmvweqnvrvIvmltklvelgrekcaqYwpl..ggsltygditvtllseev.......lddytvrtlevtnldlldgdgesrt
VDILLYSAWPEHGAPQEAYPALEILKFCETY----KKNVLVHCSEGVGRTGTLVAIKYGIDLCLKKKVTQIIDIILPVRQCRHGAVQDDTQVTYILLCVT
| .. | .||.||.|. . . |..|... .. .. |.|||| |||||||..|. . ... .|... . ... .|..|.|.|| | .. ..
vthfhytnwpdhgvpdspellldflrlvrkalasgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlreqRpgmvqtpeqyrfvyeall
|
|||||||||
| 0045450 | (Phosphotyrosine protein) phosphatases II | 759-1047 | 3e-50 | 167.0 | In-house | 13-302 (307) | alignment | ||
Range on Protein: 759-1047
Range on HMM: 13-302/307.0
HSVKAIQYQMKENKTLLQEWLKSVYRALRT-IGETSVTNYDDNISERRHSMYICEPSTMAVLEG-----FKNPFINANVMMF----------GKIEWIMA
..............|.|... ..... . .||.|.... |.. .|.. ... ..| .| . .|||. ... | ..|..
kllllvllllldfltgllkefekllsvtvfllgeysiallpenkdknrykdilpydhtRVklssldgsledsdYiNAsyvrvpllllldgydlkrkfIat
QGPMDGtekkkdetdkpkrsTCEKHWALIEQHNVAICVQLCGFVEGEDKKCASYYSDKvGGVLRFRNYSLKTIDIKTdlaeftdKKDFTLYTVEITNYrk
|||... |.|..| .. ...| . | |...|| ...||| |..|. |..| ..|. ....... ....|..|.|.|..
qgPlpe..............tvedFwrmlweqgvtvivmltelvelgrekcaqywPde.geeltygnftvtllseeh.......ldgytvrtlevtdl..
NKGEQKKTVDILLYSAWPEHGAPQEAYPALEILKFCET------YKKNVLVHCSEGVGRTGTLVAIKYGIDLCLKKKV---TQIIDIILPVRQCRHGAVQ
.. .. || .. | .||.||.|. ..|.... ... .. |||||| |||||||..|. . ... | .. . ... .|..|.||||
dgtgesrtvthfhytgwpdhgvppsfeelldfieevrkaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavq
DDTQVTYILLCVTK
| .. .. .
npeqyrflyealle
|
|||||||||
| 0043336 | (Phosphotyrosine protein) phosphatases II | 761-1045 | 1.3e-45 | 151.4 | In-house | 8-273 (278) | alignment | ||
Range on Protein: 761-1045
Range on HMM: 8-273/278.0
VKAIQYQMKENKTLLQEWLKSVYRALRtiGETSVTNYDDNISERRHSMYICEPSTMAVLEGFK----NPFINANVMMFG--KIEWIMAQGPMDGtekkkd
.||... .. .||||.. ..... ...|.... .|.. .|.. ... .... .|. .. . .|||. . . . ..|..|||...
lkallelllnlktllllefeellsfkl..dtysiallpenkdknrykdilpydhsrvklsllggdldsdYinAsyvdgynvprkfiatqgPlpe......
etdkpkrsTCEKHWALIEQHNVAICVQLCGFVEGEDKKCASYYSdkvGGVLRFRNYSLKTIDIKTdlaeftdKKDFTLYTVEITNyrkNKGEQKKTVDIL
|.|..| .. ...| . | |...|| . .||| |.. ||.|.. ... ....... ..|.|..| |.|| .. ...|| ..
........tvedFwrmvwelgvttivmLtelvelgrvkcaqYwp...ggsltygdftvtllkeeh.......lddytvrtlevtn...lgdgesrtvthy
LYSAWPEHGAPQEAYPALEILKFCET----YKKNVLVHCSEGVGRTGTLVAIKYGIDLCLKKKVTQIIDIILPVRQCRHGAVQDDTQVTYILLCV
| .||.||.| . |..||. . .. |||||| |||||||..|. . ... | . . ... .|..|.|||| . | .. ..
hylgwpdhgvpeslsllldflkavrealedsngpvlVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqRpgavqtpsqyrflyeal
|
|||||||||
| 0040438 | (Phosphotyrosine protein) phosphatases II | 762-1062 | 1.3e-53 | 177.7 | In-house | 7-289 (317) | alignment | ||
Range on Protein: 762-1062
Range on HMM: 7-289/317.0
KAIQYQMKENKTLLQEWLKSVYRALRTigETSVTNYDDNISERRHSMYICEPSTMAVLEGFK----NPFINANVMMFG--KIEWIMAQGPMdgtekkkde
.|... .| ..|.|.|. . ... ..||... .|.. .|.. ... ... .| .. . .|||. . . | ..|..|||.
lalldllksdftalleefedllslkld..tysvaelpenkdknrypdilpydhsRVkLsplggdldsdYInAsyvdgpnlkrkfIatqgPl.........
tdkpkRSTCEKHWALIEQHNVAICVQLCGFVEGEDKKCASYYSDkvGGVLRFRNYSLKTIDIKTdlaeftdKKDFTLYTVEITNYrknKGEQKKTVDILL
.|.|..| .. ...| . | |. ..| ...||| |... |..| . ... ....... ....||.|.|.... ..... || ..
.....pntvedFwrmvweqgvtvivmLteleelgrekcaqYwpl..getltygdftvtllseee.......lagitlrtlevedl...gdsesrtvthfh
YSAWPEHGAPQEAYPALEILKFCETY----KKNVLVHCSEGVGRTGTLVAIKYGIDLCLKKKVTQIIDIILPVRQCRHGAVQDDTQVTYILLCVTKGLME
| .||.||.|. . |..|...... .. |||||| |||||||..|. . .... |.. . ... .|..|.|||| | .. .. . |.
ytgWpdhgvppspdllldfleavrealedpggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrflydalleylkr
KMPVPYLRSFD
|.. ... ..
kltlepaselk
|
|||||||||
| subfamily_Cele-PTP-7_pd | Subfamily Cele-PTP-7 | 764-1063 | 1.1e-170 | 560.8 | In-house | 1-302 (302) | alignment | ||
Range on Protein: 764-1063
Range on HMM: 1-302/302.0
IQYQMKENKTLLQEWLKSVYRALRTIGETSVTNYDDNISERRHSMYICEPSTMAVLEGFKNPFINANVMMFGKIEWIMAQGPMDGTEKKKDETDK---PK
|....|.|||||.|.|..|.|||........||....|||||.|..||||.|||.|..|||.||||||.....|.||||||||||||||.....| ||
igadrklnktlleefleyveraleklkkktstnlekdiserrkslficepktmaklvdfkndfinanvlkldeikwimaqGpmdGtekkekvskkpivpk
RSTCEKHWALIEQHNVAICVQLCGFVEGEDKKCASYYSDKVGGVLRFRNYSLKTIDIKTDLAEFTDKKDFTLYTVEITNYRKNKgEQKKTVDILLYSAWP
.||.|||||||||.||||.||||.|||.|.||||.||||||||.|.|..|..||...||||.||||||.|.||||||.|..|.| ..|||||||..||||
kstlekhwalieqynvaivvqlcsfvedeekkcaeyysdkvggelkfgrytvktvsvktdleeftdkksfklytveiknekkkk.kvkktvdilafsawp
EHGAPQEAYPALEILKFCETYKKNVLVHCSEGVGRTGTLVAIKYGIDLCLKKKVTQIIDIILPVRQCRHGAVQDDTQVTYILLCVTKGLMEKMPVPYLRS
.||||.|||.||.||||||.||||||||||.|||||||||||||||.||.|||||....|.|||||||.|||||..|..|.|||||||||||..|.||||
dhGapkeaytaldilkfcesykknvlvhcsaGvGrtGtlvaikyGiqlcskkkvtdllsivlpvrqcryGavqdeqqliylllcvtkglmekagvlylrs
FDA
|||
fda
|
|||||||||
| subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 770-1041 | 1.4e-29 | 98.3 | In-house | 19-275 (305) | alignment | ||
Range on Protein: 770-1041
Range on HMM: 19-275/305.0
ENKTLLQEWLKSVYRAlRTIGETSVTNYDDnISERRHSMYICEPSTMAVLEGFKNP---FINANVMM--FGKIEWIMAQGPMdgtekkkdetdkpkRSTC
.... |.. ||.|. . . .. . ..| ... . ... . . | ... .|||. . .| ..|.||||. ..|
ysdkgleaqykslyee.eesidvgkkeank.aknrlkeitlldddriiltekeslddsdyinasyvdgykrkkkyivaqgPl..............kntv
EKHWALIEQHNVAICVQLCGFVEGEDKKCASYYSDKVGGVLRFRNYSLKtidiktdLAEFTDKKDFTLYTVEITNYRKnkGEQKKTVDILLYSAWPEHGA
. | || . | |.|.. |||...|| |. .... . .| ..|.. | ... .|.. ..|.. .. ....|| . ||.||
adfWrliveekvstivmltklveggkdkCrqYWpesktekkefgefsve.......lksektasdyieRklkisiede..dkesrtvlqyqltdWPdhGv
PQEAYPALEILKFCE-TYKKN----VLVHCSEGVGRTGTLVAIKYGIDLCLKKKVTQIIDIILPVRQCRHGAVQDDTQVTYI
||.| |...| . ..||. .|||||.||||||. .|.. .. . | .| .. ... .|. | ..|| | ...
pqfatsllslikrvqkdqkkdkgvpllVhCsagvgRtGvfiavdialerlkkEevvdvfevlkqlRskrmkmvqtldqYvfl
|
|||||||||
| 0050432 | (Phosphotyrosine protein) phosphatases II | 771-1051 | 3.8e-53 | 176.2 | In-house | 40-301 (308) | alignment | ||
Range on Protein: 771-1051
Range on HMM: 40-301/308.0
NKTLLQEWLKSVYRALRtIGETSVTNYDDNISERRHSMYICEPSTMAVLeGFKNPFINANVMMFG----KIEWIMAQGPMdgtekkkdetdkpkRSTCEK
...||.|. . ... ..|.||.. .|.. |.. ... .. .| . .. .|||. ... . ..|..|||. .|.|.
dlglleeefeellsvkp.lleysvallpenkdkNrykdilpydhsRVkl.degsdYInAsyvdgyssklprkfIatqgPl..............pntved
HWALIEQHNVAICVQLCGFVEGEDKKCASYYSDKVG-GVLRFRNYSLKTIDIKTdlaeftdKKDFTLYTVEITNYRKNkgeQKKTVDILLYSAWPEHGAP
.| .. ..|| . | |. .|| . .||| |. ...| |.|.. ........... ..|.|..|.|.||.... . .|| .. | .||.||.|
FwrmvweqnvrvIvmLtklvengrekcaqYwplelgggsleygkftvtllseev.......lddytvrtleltnlgdg...esrtvthfhytnWpdhgvP
QEAYPALEILKFCETY--KKNVLVHCSEGVGRTGTLVAIKYGIDLCLKKKVTQIIDIILPVRQCRHGAVQDDTQVTYILLCVTKGLME
... . |..|...... .....|||| |||||||..|. . ... |.. . ... .|..|.|.||. | .. .. . |.
pspeilldflelvrkslpggpivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkklReqRpgmvqtpeqylflyralleylkl
|
|||||||||
| 0039614 | (Phosphotyrosine protein) phosphatases II | 771-1053 | 3.6e-47 | 156.6 | In-house | 30-293 (297) | alignment | ||
Range on Protein: 771-1053
Range on HMM: 30-293/297.0
NKTLLQEWLKSVYRALRtigETSVTNYDDNISERRHSMYICEPSTMAVLEGFKN-----PFINANVMMFGKI---EWIMAQGPMDGtekkkdetdkpkrs
.||||... ..... ..|... |.. .|.. ... .... .| .... .|||. . . .. ..|..|||...
sktllllefeellslkp...dysiallpenkdknrykdilpydhsrvklkpedgvdldsdYinAsyvdgydlltrkfIatqgPlpe..............
TCEKHWALIEQHNVAICVQLCGFVEGEDkKCASYYSDKVGgvlRFRNYSLKTIDIKTdlaeftdKKDFTLYTVEITNyrknkGEQKKTVDILLYSAWPEH
|.|..| .. ...| . | |. .|| . |||.|.....| .. ... ....... ....|..| |.|| ... .|| ..| ||.|
tvedFwrmvweqgvtvivmLtklvelgr.kcaqywpeegg...tygdftvtllkveh.......ldgytvrtlevtn.....ngesrtvthfqytgwpdh
GAPQEAYPALEILKFCET------YKKNVLVHCSEGVGRTGTLVAIKYGIDLCLKKKVTQIIDIILPVRQCRHGAVQDDTQVTYILLCVTKGLMEKM
|.|. . ||.|..... .. |||||| |||||||..|. . .... |.. . ... .|..|.|||| . | .. .. . |. |.
gvppslellleflelvrealaelpkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavqtpsqyrflydallellkrkl
|
|||||||||
| 0036941 | (Phosphotyrosine protein) phosphatases II | 773-1060 | 3.3e-56 | 186.1 | In-house | 13-288 (297) | alignment | ||
Range on Protein: 773-1060
Range on HMM: 13-288/297.0
TLLQEWLKSVYRALRtIGETSVTNYDDNISERRHSMYICEPSTMAVLEGFKNPFINANVMMFGK--IEWIMAQGPMDgtekkkdetdkpkrSTCEKHWAL
.||... ..... | .|..||... .|.. |.. ... ..|. .|.. .. .|||. . . . ..|..|||.. .|.|..| .
alllkefeellplll.lgslsvallpenleknRykdilpydhtRVklddegsdYinAsyvdgydlkrkfIatqgPlp..............ntvedFWrm
IEQHNVAICVQLCGFVEGEDKKCASYYSDKVGGVLRFRNYSLKTIDIKTDlaeftDKKDFTLYTVEITNYrknKGEQKKTVDILLYSAWPEHGAPQEAYP
. ..|| . | |. .|| . .|||.|.....|..| . ............ ...|.||.|.|.|.. ......|| .. | ||.||.|. ...
vweqnvtvIvmltelvelgrekcaqywpleegesltygdftvtllsvevv.....llddytlrtlevtdt...gngesrtvthfhytgwpdhgvpespas
ALEILKFCET------YKKNVLVHCSEGVGRTGTLVAIKYGIDLCL---KKKVTQIIDIILPVRQCRHGAVQDDTQVTYILLCVTKGLMEKMPVPYLRS
|........ .. |||||| ||||.||..|. . ... | . | .... .|..|.|||| | .. .. . |. |.....|..
lldfielvrkvlkllpsggpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyeallellkkkltkepllk
|
|||||||||
| 0047943 | (Phosphotyrosine protein) phosphatases II | 773-1046 | 5.6e-50 | 165.7 | In-house | 13-269 (273) | alignment | ||
Range on Protein: 773-1046
Range on HMM: 13-269/273.0
TLLQEWLKSvyRALRTIGETSVTNYDDNISERRHSMYICEPSTMAVLEGFKNPFINANVMMF--GKIEWIMAQGPMdgtekkkdetdkpkRSTCEKHWAL
.||.|. . . | .....||... .|.. |.. ... ... .|.. .. .|||. . . | ..|..|||. .|.|..| .
llleefell..lslkplltysvallpenkdknrykdilpydhsrvklgdggsdyinAsyvdgynlkrkfiatqgPl..............pntvedfwrm
IEQHNVAICVQLCGFVEGEDKKCASYYSDKVGG-VLRFRNYSLKTIDIKTdlaeftdKKDFTLYTVEITNYRKNKgeqKKTVDILLYSAWPEHGAPQEAY
. ..|| . | |. .|| . .||| |.....|. .|.. ... ......| |.|.|..|.|.||. .. ..|| ...| ||.||.|.
vweqnvrviVmLtelvelgrekcaqYwpleggelsltygkftvtllseet.......kddytvrtleltnlgtge...srtvthfhytgwpdhgvppsle
PALEILKFCET------YKKNVLVHCSEGVGRTGTLVAIKYGIDLCLKKKVTQIIDIILPVRQCRHGAVQDDTQVTYILLCVT
. ||....... .. |.|||| |||||||..|. . .|. |.. . ... .|..|.|.|| | .. ..
sllefielvrkalealpsngpvvVHCsaGvgRtgtfialdllldqlekeggvdvleavkllrsqRpgmvqtpeqyrflyeall
|
|||||||||
| 0046845 | (Phosphotyrosine protein) phosphatases II | 774-1052 | 8.5e-49 | 161.8 | In-house | 2-277 (284) | alignment | ||
Range on Protein: 774-1052
Range on HMM: 2-277/284.0
LLQEWLKSVYRALRTIGETSVTNYDDNISERRHSMYICEPSTMAVLEGFKN-----PFINANVMMFG-------KIEWIMAQGPMDGtekkkdetdkpkr
| .|. . . . ..||... |.| |.. ... .. .| ... .|||. . . | ..|..|||...
leeefeellsltvklllslsvallpenlsknRykdilpydhsRVklksldgdledsdYinAsyvdgydldltyikkkfIatqgPlpn.............
sTCEKHWALIEQHNVAICVQLCGFVEGEDKKCASYYSDKvGGVLRFRNYSLKTIDIKTdlaeftdKKDFTLYTVEITNYrkNKGEQKKTVDILLYSAWPE
|.|..| .. ..|| . | |...|| . .||| |.... |.||.. ... ....... |.|.|..|.|.||. . ... .|| .. | .||.
.tvedFwrmvweqnvrvIVmltelvengrekcaqYwple.gevltygdftvtllseev.......kddytvrtleltnl..gytgesrtvthfhytswpd
HGAPQEAYPALEILKFCETY------KKNVLVHCSEGVGRTGTLVAIKYGIDLCLKKK---VTQIIDIILPVRQCRHGAVQDDTQVTYILLCVTKGLMEK
||.|... . ||.|...... .. ..|||| |||||||..|. . ... |.. . . ... .|..|.|.|| | .. .. |. |
hgvppspedlleflrlvrellenlpgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvqtleqyrfvyealleylklk
|
|||||||||
| subfamily_PTPN3_pd | Subfamily PTPN3 | 781-1051 | 4.8e-25 | 83.0 | In-house | 23-277 (280) | alignment | ||
Range on Protein: 781-1051
Range on HMM: 23-277/280.0
SVYRALRTIgETSVTNYDDNISERRHSMYICEPSTMAVLEGFKNPFINANVMMFgkiewimaQGPMDGTEKKKDETDKPKRSTCEKHWALIEQHNVAICV
.|| . . ..|... .|.| |. . .| |. .. .|||| . . . | |. .. | | ..|... | .. .... . |
qlyrkkpgl.aisaarkpenlsknryrdilpydatrvklkesetdyinanyvnm........eipstglvnryiatqGPlaktatdfWqmvweqkssliv
QLCGFVEGEDKKCASYYSDkVGGVLRFRNYSLKTIDIktdlaefTDKKDFTLYTVEITNyrKNKGeQKKTVDILLYSAWPEHGAPQEAYPALEILKFCET
| || .|| |. . . |.. ..|.| .| . | . ... |.. ..... | | |||.|| |... ||... ..
mlttlverGrvkChqyWPe.tedeleygefsvkceke.......detksyvlrelvlkd..ketk.eerkilqlqylaWpdhgvPddsadflefvervrk
YK----KNVLVHCSEGVGRTGTLVAIKYGIDLCLKKKVTQIIDIILPVRQCRHGAVQDDTQVTYILLCVTKGLME
.. . |.|||| |.|||| |.... . | ... ..||. .|. | || .| ... .. | .|
lrsgkeePvvvhCsaGigrtGvlilletalalieaaepvypldivrtmrdqramlvqtasqykfvCeailkvyee
|
|||||||||
| subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 782-1051 | 2.4e-25 | 84.2 | In-house | 20-278 (281) | alignment | ||
Range on Protein: 782-1051
Range on HMM: 20-278/281.0
VYRALRTIG--ETSVTN-YDDNISERRHSMYICEPSTMAVL----EGFKNPFINANVMM--FGKIEWIMAQGPMdgtekkkdetdkPkrSTCEKHWALIE
|..|. || .|.. |.|. . |.| . | .. | .. .|||| . |. |.| .|||. | ..... | ..
eyeklaaigvdntataskadenvlknrYsnivaYDatrvkvtpneenkntDYinanfvpgykgekeyiatqgPv............P..aslvafWqmvw
QHNVAICVQLCGFVEGEDKKCASYYSDKVGgvlrfrnySLKTIDIKTDLAEFTDKKDFTLYTVEItnyrKNKGEQKKTVDILLYSAWPEHGAPQEAYPAL
...| . | . .|.. || |. |. .|| |.. . ..|. . .... .... ....| | | |||.||.|... |
eqkvsaivmvtreieagklkChrYWPddns........elkygdvtvkstaeeekatyierkfkl....eresgetreveqlaytaWPdhGvPattkell
EILKFC----ETYK-KNVLVHCSEGVGRTGTLVAIKYGIDLCLKK-KVTQIIDIILPVRQCRHGAVQDDTQVTYILLCVTKGLME
| | |. . ...||| ||||||| .|. .. . .. . ... ... .|. | || .| ... . | . |..
efrkevlkltekktkaplvihCsaGvGrtGtyialDrlvkaveaeleeldvkavvaelrkernlmvqtvvqyefvykavldaldk
|
|||||||||
| subfamily_PTPN13_pd | Subfamily PTPN13 | 784-1041 | 4e-24 | 80.3 | In-house | 21-261 (273) | alignment | ||
Range on Protein: 784-1041
Range on HMM: 21-261/273.0
RALRTIGETSVTNYDDNISERRHSMYICEPSTMAVLEGfKNPFINANVMmfgKIEWimaqgpmDGTEKKKDETDKPKRSTCEKHWALIEQHNVAICVQLC
| |... ...|.. ..| .. |. . | |.. . ..|||. . |.. . | . . | |.. | .. . .. . . .
relkpldtcevgkkkenkdknryrnvlPydetrvklgd.eggyinasli...kvpv.......gkdeyeyiacqGPlPetvkdfwqmvweqkaeviamvt
GFVEGEDKKCASYYSDKVGGVLRFRNyslktiDIKTDLAEFTDKKDFTLYTVEITNyrkNKGEQKKTVDILLYSAWPEHGAPQEAYPALEILKFCETYKK
.|.. || |. .. . | .| .. .| . .....|.. ...... .. .. . | | . .||.|| |..| . |.... . ..
lekekgkvkchrywPesknkklkvsn......rlevellkvqkldgfvvralavkd...sesgesrevahlnfvkwPdhgvPssaaellqfvaevrrlqt
---NVLVHCSEGVGRTGTLVAIKYGIDLCLKKKVTQIIDIILPVRQCRHGAVQDDTQVTYI
..|||| |.||.|||..|. ..| ..| .. .|. .|. |.| || . | ..
dagPivvhcsaGiGrsGtlitidvvlglierdkefdvkeivrklreqrqgvvqtkdqyifv
|
|||||||||
| 0045098 | (Phosphotyrosine protein) phosphatases II | 785-1050 | 2.1e-44 | 147.4 | In-house | 18-273 (278) | alignment | ||
Range on Protein: 785-1050
Range on HMM: 18-273/278.0
ALRTIGETSVTNYDDNISERRHSMYICEPSTMAVlegfknPFINANVMMFGKIEWIMAQGPMDgtekkkdetdkpkrSTCEKHWALIEQHNVAICVQLCG
.| ..| .. .| .|.. | . ... .... . .|||. ... . ..|..|||.. ||....| .. .... . | |..
llgipseitpalylgnldknRykdilpydhsrVk......dYINAsyidgypkkfIatqgPlp..............stvadfwrmlwelgitvivmlte
FVEGEDKKCASYYSDkvGGVLRFRNYSLKTIDIKTDlaeftDKKDFTLYTVEITNYRKNKGEqKKTVDILLYSAWPEHGAPQEA--YPALEILKFCET--
.||.. .||| |. . ||.|.. ........... |. . ..|. ...... .| . .| .| | ||.||.| . . ||.|.|..
lvelgrekcaqywpe..ggsltygdftvtllseevl.....ddytlrtllvtnltveredle.srgvthlhylpwpdhgvpslpilksflellefireal
---------------YKKNVLVHCSEGVGRTGTLVAIKYGIDLClkKKVTQIIDIILPVRQCRHG-AVQDDTQVTYILLCVTKGLM
.. |||||| ||||||||||. . ..|. ... . ... .|..|.| ||| | .. .. . |.
kllaslllsslllldsggpvlVHCsaGvgRtGtlvaaylmlell..eggvdlleavkelrsqRpglavqnleqyrflyefllelll
|
|||||||||
| DSPc_SM00195 | 789-1047 | 3.2e-46 | 153.2 | In-house | 16-260 (263) | alignment | |||
Range on Protein: 789-1047
Range on HMM: 16-260/263.0
IgETSVTNYDDNISERRHSMYICEPSTMAVLEGF----KNPFINANVMMF--GKIEWIMAQGPMdgtekkkdetdkpkRSTCEKHWALIEQHNVAICVQL
||. .. . | | |...... .| |. .. .||||.. . | ..|..|||. ||.|..| .. ...| | | |
k.etteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPl..............pstvedFWrmvweekvkiivml
CGFVEGEDKKCASYYSDKVGGVLRFRNYSLKTIDIKTDLaeftdkKDFTLYTVEITNYRKnkgEQKKTVDILLYSAWPEHGAPQEAYPALEILKFCETYK
. ..| . .||..|. .. || .| ..|.|... ... ....|.|.|.|. | |....| . | .||.||.|... . ||.|..... |
teeeengkekcdrywpeesggketfgkisvklvevekkk......deiilrtleltkegk...eetrkvtqyqyknWpdhgvpdstksvlellravkksk
K----NVLVHCSEGVGRTGTLVAIKYGIDLCLKKKVTQIIDIILPVRQCRHGAVQDDTQVTYILLCVTK
. ..|||| |||||||.|.|.. .. . ..| .| .|. .|. |.|.|| ..| ..| .. .
stssgpivVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaile
|
|||||||||
| PTPc_SM00194 | 789-1047 | 3.2e-46 | 153.2 | In-house | 16-260 (263) | alignment | |||
Range on Protein: 789-1047
Range on HMM: 16-260/263.0
IgETSVTNYDDNISERRHSMYICEPSTMAVLEGF----KNPFINANVMMF--GKIEWIMAQGPMdgtekkkdetdkpkRSTCEKHWALIEQHNVAICVQL
||. .. . | | |...... .| |. .. .||||.. . | ..|..|||. ||.|..| .. ...| | | |
k.etteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPl..............pstvedFWrmvweekvkiivml
CGFVEGEDKKCASYYSDKVGGVLRFRNYSLKTIDIKTDLaeftdkKDFTLYTVEITNYRKnkgEQKKTVDILLYSAWPEHGAPQEAYPALEILKFCETYK
. ..| . .||..|. .. || .| ..|.|... ... ....|.|.|.|. | |....| . | .||.||.|... . ||.|..... |
teeeengkekcdrywpeesggketfgkisvklvevekkk......deiilrtleltkegk...eetrkvtqyqyknWpdhgvpdstksvlellravkksk
K----NVLVHCSEGVGRTGTLVAIKYGIDLCLKKKVTQIIDIILPVRQCRHGAVQDDTQVTYILLCVTK
. ..|||| |||||||.|.|.. .. . ..| .| .|. .|. |.|.|| ..| ..| .. .
stssgpivVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaile
|
|||||||||
| subfamily_Ptp69D_pd | Subfamily Ptp69D | 790-1041 | 3e-22 | 74.1 | In-house | 38-278 (307) | alignment | ||
Range on Protein: 790-1041
Range on HMM: 38-278/307.0
GETSVTNYDDNISERRHSMYIC---EPSTMAVLEGFK-NPFINANVMM-F-GKIEWIMAQGPMDgtekkkdetdkpkrSTCEKHWALIEQHNVAICVQLC
.|.|.. ..| |. . . .....| . .|||. . . | ..|.||.|.. .| . | .| . .| . | |
kstkvsekkenalknRyedikafDktRvkLkkingkedsdYinasfikgykekkkfiaaqdPve..............atigDfWRmiaeqevtlivmls
GFVEGEDKKCASYYSDKvgGVLRFRnyslktiDIKTDLAEFTDKKDFTLYTVEITNYRKNKGEQKKTVDILL--YSAWPEHGAPQEAYPALEILKFC-ET
| ..|||| |... .. || .|... ..|.. ...... .. || ... .. | .|.. .|. | |.... |
nlteknrkkcakYWpie..devqyg.......dilvklvseekhsdyiiReldvskkkeesgevedsrkvvqyhytgWkDskvPevargllklieqvrel
YKKN---VLVHCSEGVGRTGTLVAIKYGIDLCLKKKVTQIIDIILPVRQCRHGAVQDDTQVTYI
||.| ..|||| ||||.|..||.. .. . . . .|.... .|. | || | ...
yklnrsPivvhCsaGvgrsgifvaldsllqqlkaedkvdifetvkdLrsqRnllvqsleqYvfl
|
|||||||||
| 0040439 | (Phosphotyrosine protein) phosphatases II | 791-1047 | 7.9e-45 | 148.8 | In-house | 2-244 (249) | alignment | ||
Range on Protein: 791-1047
Range on HMM: 2-244/249.0
ETSVTNYDDNISERRHSMYICEPSTMAVLEG----FKNPFINANVMMF--GKIEWIMAQGPMDGtekkkdetdkpkrsTCEKHWALIEQHNVAICVQLCG
|.||... |.. .|.. ... .... .|. | . .|||... . | ..|..|||... |.|..| .. .... . | |.
eysvallpenkdknrypdilpydhsrvklsilpglflsdyinAsyidgyyikrrfiatqgPlpe..............tvedfwrmlwelgitvivmLts
FVEGEDKKCASYYSDkvGGVLRFRNYSLKTIDIKTdlaeftdKKDFTLYTVEITNYrknKGEQKKTVDILLYSAWPEHGAPQEAYPALEILKFCET----
.|| . .||| |... ||.| . ... ....... |.|.|..|.|.||. . .. || . | ||.||.|. ..|.... ...
lvelgrekcaqywpl..ggsleygdftvtllsvev.......kddytvrtleltnl...ydgesrtvlhiqytdwpdhgvppsfedlldfieavrkalee
--YKKNVLVHCSEGVGRTGTLVAIKYGIDLCLKKKVTQIIDIILPVRQCRHGAVQDDTQVTYILLCVTK
.. |||||| |||||||..|. . ... |.. . ... .|..|.|||| . | ... .. .
lpkggpvlVHCsaGvgRtGtfiaaylmleqlekelgvdleeavkllrsqRpgavqnpeqyrflyealle
|
|||||||||
| subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 791-1040 | 6.2e-28 | 92.3 | In-house | 47-274 (290) | alignment | ||
Range on Protein: 791-1040
Range on HMM: 47-274/290.0
ETSVTNYDDNISERRHSMYICEPSTMAVL-EGFKNPFINANVMMFGKIEWIMAQGPMdgtekkkdetdkpkRSTCEKHWALIEQHNVAICVQLCGFVEGE
| .. . . .. |. .|. | .| .|.. .. || . | .|..||.. ..| | .. |..|| | || .|
erkifdkntefkknrykdvvcndktrvilkdGydGdyvhanyvkGlkamfiltqGal..............kdtvidiwrmvlqekvaaivmlceliedG
DKKCASYYSDKVGGVLRFRNYSLKTiDIKTDLAEFTDKKdftlyTveITNYRKNKGEQKKtVDILLYSAWPEHGAPQEAYPALEILKFCETYKKNVLVHC
||. || .| | || | .... ..| . . || | .. |..| ..| . | .||.. .. . | .|. . | |||
kakceqyypekeGevltfGeitvlc.seeddkdaniikk.....t..lsvrdkdsGkehk.lkhlkikswpdksvalstlallrtlrilrkasGpvvvhc
SEGVGRTGTLVAIKYGIDLCLKKKVTQIIDIILPVRQCRHGAVQDDTQVTY
| |.|||||.|||. |... |. | ...|.. .|..| ..|| |.|
saGiGrtGtfvaievglqilldGkeldlldlvralrnsrlnsvqvdiqyla
|
|||||||||
| subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 791-1047 | 3.1e-24 | 80.7 | In-house | 47-288 (298) | alignment | ||
Range on Protein: 791-1047
Range on HMM: 47-288/298.0
ETSVTNYDDNISERRHSMYICEPSTMAVLEG----FKNPFINANVMMfgkiewimaqgPMDGTEkKKDETDKPKRSTCEKHWALIEQHNVAICVQLCGFV
|..|.....| . |.. .| |. ||| . .||| . ..|.. | .| .| | | .. ..... | | .
ekevarkpenkkkNRyadiialdssRvvLekedadeesdYiNAsflh...........aykgrn.afiatqaPltetvedFWrmvteedigtiVmltnle
EGEDKKCASYYSDKvggvlRFRNYSLKTIdiktDLAEFTDKKDFTLYTVEITnyrKNKGEQKKTVDILLYSAWPEHGAPQEAYPALEILKFCETYKK---
| . |. |. |. . ..| |. .| . .. |.. ..... |.| |....| | .. ||..|.|..| |..|. .....
eldktkyhkywPde.....gketygeitv....sllskeefadlivrklkvs...kkkeekerevrqlhftsWpdkgvpenatsvldllrkvrasqqqag
--NVLVHCSEGVGRTGTLVAIKYGIDLCLKKKVTQIIDIILPVRQCRHGAVQDDTQVTYILLCVTK
|.|.||.||||.|| .||. .. |..| . ... .|. | |||| .| ..| | .
nkpvivqCsaGvgRsGtfiaidsvlervkkeqvvDvfqvvkvlRkkrpgavqteeqYvfiyeavle
|
|||||||||
| subfamily_Cele-PTP-8_pd | Subfamily Cele-PTP-8 | 792-1053 | 5.4e-25 | 83.0 | In-house | 35-275 (288) | alignment | ||
Range on Protein: 792-1053
Range on HMM: 35-275/288.0
TSVTNYDDNISERR-HSMYICEpSTMAVLEGFKNPFINANVMMfgkiewimaqgpmD-GTEKKKDETDKPKRSTCEKHWALIEQHNVAICVQLCGFVEGE
..... .| .. | . .. |. | |. . .|.|||. ... .. | ..| |. | .. . .| | || ..|
diidsfianptrdryenlprcd.itrvklsddpdfyiaanvvs.............sakykrrlicaqaPlngtieelWkmllesdveyivmlcellekG
DKKCASYYSDKVGGVLRFRNYslktidiktdlAEFT-DKKDFTLYTVEITNYRKNK-GEQKKTVDILLYSAWPEHGAPQEAYPALEILKFCETYKKNVLV
.| | |. |.| |.. . . .|.. .|... | .| ||.|. | || . |...| |.. . | .|. ....| ..|
keksaeyfPsklGekarigrl...........ctvvkkkradidklvkvsllriskegeekvivkilhlleWdddgvPenylsplrllevlkslqkPivv
HCSEGVGRTGTLVAIKYGIDLCLKKKVTQIIDIILPVRQCRHGAVQDDTQVTYILLCVTKGLMEKM
|.|.||||||||. | .. . | .. |. | |.| | |. || . |. |
hssaGvGrtgtlililialeslrlddflgirsllaklreerfkaiqtemqylyvhrcvleelllkk
|
|||||||||
| 0042113 | (Phosphotyrosine protein) phosphatases II | 793-1045 | 5.9e-41 | 135.9 | In-house | 2-239 (245) | alignment | ||
Range on Protein: 793-1045
Range on HMM: 2-239/245.0
SVTNYDDNISERRHSMYICEPSTMAVLEGFK----NPFINANVMMFGKI--EWIMAQGPMDGtekkkdetdkpkrsTCEKHWALIEQHNVAICVQLCGFV
||... |.. .| | ... ..|. .| . ...|||. . . .| .|..|||... |.|..| .. .... . | |. ..
svallpenkdknrysdilpydhtrvklspdggdldsdyinasyvdgyritpkfiatqgPlpe..............tvedfwrmlwelgittivmLteee
EGEDKKCASYYSDkvGGVLRFRNYSLKTIDIKTdlaeftdKKDFTLYTVEITNYrknKGEQKKTVDILLYSAWPEHGAPQEAYPALEILKFCET-----Y
| . .||| |... |..|.. ... ....... ..|.|..|.|.|| . ....| ..| ||.||.| |..|.|...
elgrvkcaqywpl..gesltygdftvtllseeh.......lddytvrtlevtnl...gddesrevihyhylpwpdhgvpdllellldflefvrkalaeds
KKNVLVHCSEGVGRTGTLVAIKYGIDLCLKKKVTQIIDIILPVRQCRHGAVQDDTQVTYILLCV
.. |||||| |||||||..|. . ... | . . ... .|..|.|||| . | .. ..
ngpvlVHCsaGvgRtGtfiaaylmleqlekelgvsleeavkelrsqRpgavqtpsqyrflyeal
|
|||||||||
| subfamily_Cele-PTP-15_pd | Subfamily Cele-PTP-15 | 793-1044 | 7.4e-26 | 85.7 | In-house | 28-265 (285) | alignment | ||
Range on Protein: 793-1044
Range on HMM: 28-265/285.0
SVTNYDDNISERRHSMYICEPSTMAVLEGFKNPFINANVM-MFGKI--EWIMaqgpmdgtekkkdeTDKPKRSTCEKHWALIEQHNVAICVQLCGFVEGE
. | |. | |.. | | ||. . .| |. | | || .| |. | | | .| | ..| . || ..||
tytayeanpdlnryadvrcieetrvvlknhdrdyihaswmrmpgkdqstyit..............tqgplpetlsdfwhmiyqekiayvlmlctlfegg
DKKCASYYSDKVGGVLRFRNYSLKTIDIKTDLAEFTdkkdfTLYTVEITNYRKNKGEQKKtVDILLYSAWPEHGAPQEAYPALEILKFCET---YKKNVL
.||| || .|.| |..| .| . . | . | | .. ..| | .. . ||.. ||..| | .|. |. . .| .
vekcalyypeklgevvkfgkyeitlteckeeaiagt.....ilnaltvintedasseply.mnhvqvpwwpdqlapedarpmielykwvkkvnpkekpic
VHCSEGVGRTGTLVAIKYGIDLCLKKKVTQIIDIILPVRQCRHGAVQDDTQVTYILLC
|||| ||||| |.| | | ... ...||. .| | ||| |. .. .
vhcsagvgrtatfvgidyatirimenpniemldivremramrfqavqshmqflflyvv
|
|||||||||
| subfamily_Sponge-PTP5_pd | Subfamily Sponge-PTP5 | 794-1041 | 2.1e-13 | 44.8 | In-house | 27-258 (283) | alignment | ||
Range on Protein: 794-1041
Range on HMM: 27-258/283.0
VTNYDDNISERRHSMYICEPSTMAVLEGFKNPFINANVMMFgkiewimaqGPMDGTEKKKDETDKPKRSTCEKHWALIEQHNVAICVQLCGFVEGEDKKC
.. |.| |. . . |. . .||| .. . .|| . | . | | .. ..... | | . |....||
iasadenkrknrnqeivpadqwrvelksesrdyinavfipv.........sksykqdkkyiiaqsPldrtvvdfWkmvfdekitaivmltklqedlrikC
ASYYSDKvgGVLRFRNYslkTIDIKTDlaefTDKKDFTLYTVEITNYrknkGEQKKTVDILLY--SAWPEHGaPQEAYPAL---EILKFC--ETYKKNVL
. |. . | . .. |. .. . | .. |. . . . . |.|. . | | | | .| .| . .. | | ..
sqyWPkr..GsedyGef...tvtlrke....ttsnsfiikelllrvn....ssakstlllahyqvidWleyg.eqaiinslvkfnkvislqteskkgPiv
VHCSEGVGRTGTLVAIKYGIDLCLKKKVTQIIDIILPVRQCRHGAVQDDTQVTYI
||||.|.|||....|. .. | . | . .. .|. | .||| | .
vhCstgiGrtavfiaasasvkdaltesvvdvfavvkimreqrmmavqtldqyklv
|
|||||||||
| 0037934 | (Phosphotyrosine protein) phosphatases II | 795-1045 | 1.4e-38 | 128.2 | In-house | 5-238 (243) | alignment | ||
Range on Protein: 795-1045
Range on HMM: 5-238/243.0
TNYDDNISERRHSMYICEPSTMAVLEGfkNPFINANVMMFGKiEWIMAQGPMDGTEKKkdetdkpkrsTCEKHWALIEQHNVAICVQLCGFVEGEDKKCA
.. |.|..|.| ... . .. .||| . .|||| .. . .| |||...| . . ...| .. .... . | |. .|| . .|||
allpenlsknrysdilpydhsrvkleg..sdyinanliyvtp.rliatqgPlpetved..........dlasfwrmlwelgitvivmltelvElgrekca
SYYSdkvGGVlRFRNYSLKTIDIKTdlaeftdKKDFTLYTVEITNyrKNKGEQKKTVDILLYSAWPEHGAPQEAYPALEILKFCETY------------K
|.. |.| .. ... ....... ..|.|..|....| .. ......| ..| .||.||.|.. . |..|... .. .
qywp...gev.tygdftvtllseeh.......lddytvrtlllen..ldlddltrlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsg
KNVLVHCSEGVGRTGTLVAIKYGIDLClkkKvTQIIDIILPVRQCRHG-AVQDDTQVTYILLCV
. |||||| ||||||||.|. . ..|. . . ... .|..|.| ||| | .. ..
gpvlVHCsaGvgRtGtliaaylmllll...g.vdleeavkllreqRpgkavqtpsqyrflyeal
|
|||||||||
| Y_phosphatase | Protein-tyrosine phosphatase | 800-1046 | 2.9e-51 | 169.5 | Pfam-A | 1-234 (235) | alignment | ||
Range on Protein: 800-1046
Range on HMM: 1-234/235.0
NISERRHSMYICEPSTMAVLEGFK--NPFINANVM--MFGKIEWIMAQGPMdgtekkkdetdkpkRSTCEKHWALIEQHNVAICVQLCGFVEGEDKKCAS
| . .|...... .|. |.| . . .||||.. | ..|..|||. ||.|..|... |..| . |.|. .| ...|||
nkkknRykdilpydktrvklkgsegpsdYInAnyvkgykekkkfIatQgPl..............kstiedFWrmvwqekvkvivmltsleekgrekcaq
YYSDKVGGVLRFRNYSLKTIdiktdLAEFTDKKDFTLYTVEITNYRKNKgeQKKTVDILLYSAWPEHGAPQEAYPALEILKFCETYK----KNVLVHCSE
|.... .. |.. ...... | .|.|..||...|... ... .|..| | | .||.||.|... . |.... .|..| ..|.||||.
Ywpeeeeesltygdikvelk.....ekekedekeytlrklelkkkkees..ekrevkqlhytnWpdhgvpespkslldlirkvekskeaksgpvvVhCsa
GVGRTGTLVAIKYGIDLCLKKKVTQIIDIILPVRQCRHGAVQDDTQVTYILLCVT
|||||||.||... .. . ... ... .|. .|..|.|.||. .| .. ...
GvgRtgtfvaldilleqleaeeevdvlqivkelRkqRpgmvqsleqYiflykail
|
|||||||||
| Y_phosphatase | Protein-tyrosine phosphatase | 800-1046 | 2.9e-51 | 169.5 | In-house | 1-234 (235) | alignment | ||
Range on Protein: 800-1046
Range on HMM: 1-234/235.0
NISERRHSMYICEPSTMAVLEGFK--NPFINANVM--MFGKIEWIMAQGPMdgtekkkdetdkpkRSTCEKHWALIEQHNVAICVQLCGFVEGEDKKCAS
| . .|...... .|. |.| . . .||||.. | ..|..|||. ||.|..|... |..| . |.|. .| ...|||
nkkknRykdilpydktrvklkgsegpsdYInAnyvkgykekkkfIatQgPl..............kstiedFWrmvwqekvkvivmltsleekgrekcaq
YYSDKVGGVLRFRNYSLKTIdiktdLAEFTDKKDFTLYTVEITNYRKNKgeQKKTVDILLYSAWPEHGAPQEAYPALEILKFCETYK----KNVLVHCSE
|.... .. |.. ...... | .|.|..||...|... ... .|..| | | .||.||.|... . |.... .|..| ..|.||||.
Ywpeeeeesltygdikvelk.....ekekedekeytlrklelkkkkees..ekrevkqlhytnWpdhgvpespkslldlirkvekskeaksgpvvVhCsa
GVGRTGTLVAIKYGIDLCLKKKVTQIIDIILPVRQCRHGAVQDDTQVTYILLCVT
|||||||.||... .. . ... ... .|. .|..|.|.||. .| .. ...
GvgRtgtfvaldilleqleaeeevdvlqivkelRkqRpgmvqsleqYiflykail
|
|||||||||
| 0041856 | (Phosphotyrosine protein) phosphatases II | 800-1053 | 1.3e-25 | 85.5 | In-house | 1-175 (182) | alignment | ||
Range on Protein: 800-1053
Range on HMM: 1-175/182.0
NISERRHSMYICEPSTMavlegfKNPFINANVMMFGKIE--WIMAQGPMDGtekkkdetdkpkrsTCEKHWALIEQHNVAICVQLCgfvegedkkCASYY
|.. .|.| ... . .. . .||||..... .|..|||... |..... .. .... . | |. . |.
nldknrysdilpydhsr......dldyInanlylgslpatrfiatqgplls..............tvadflrmlkelgittivnlt.........eelyw
SDKVggvlrfrnyslktidiktdlaeftdkkdftlytveitnyrknkgeqKKTVDILLYSAWPEHGAPQeAYPALEILKFCETYKKNVLVHCSEGVGRTG
... .... .|| || ||.| . .|.... .. ...|||||| ||||||
pell..............................................erlgiqylylpwpDhgvpd.ldelldfieevleeggpvlVHCsaGvgRtg
TLVAIKygidLCLKKKvTQIIDIILPVRQCRHGAVQDDTQVTYILLCVTKGLMEKM
||||. |..|.. . ... ||..|.|.|. | .. |.. |. |.
tlvaay....lmkklg.vsleeavklvrsrRpgmvitpnqyfflqlallellllkk
|
|||||||||
| subfamily_egg_pd | Subfamily egg | 805-1034 | 2.7e-07 | 24.6 | In-house | 45-255 (307) | alignment | ||
Range on Protein: 805-1034
Range on HMM: 45-255/307.0
RHSMYICEPSTMAVLE----GFKNPFINANVMMFGKI--EWIMAQGPMdgtekkkdetdkpkRSTCEKHWALIEQHNVAICVQLCGFVEGedKKCASYYS
| . |. |. || . . || || . . . |.|.|| |. . | . | .. | .| | | .| ..| |.
rskrvhckdssrvklelrrGqylddfihanrvkGkpllnefilaqapl..............kntvddfwrmvfqeevqyivmltsrkes..erceyywp
DKVGGVLRFRNYSLKTIDIKTDlaeftDKKDfTLYTveITNYRKnKGEQKKTVDiLLYSAWpEHGAPQEAYPALEILKFCETYKKNVLVHCSEGVGRTGT
|.. ||. .| | .| | |.. .|. . | ... | . . . . | |..|. | |.|.. .|| ...|
kaesdslvtvpGslrienlkvd.....skad.plfr..vtklkl.vGgddeerf.lehwqg.dvnnssdvysplrvlrklrnlskpvvvqdilGvskaat
LVAIKYGIDLCLKKKVTQ--IIDIILPVRQCRHGAVQD
||||. . |. .|. . . .|. |. .|.
lvaieiallsllrGpitkslvlravvflrlrrrlsves
|
|||||||||
| subfamily_PTPRK_pd | Subfamily PTPRK | 813-1043 | 3.1e-19 | 63.9 | In-house | 60-271 (314) | alignment | ||
Range on Protein: 813-1043
Range on HMM: 60-271/314.0
PSTMAVLEGFKNPFINANVMmfgkiewimaqgpmDGTEKKKD--ETDKPKRSTCEKHWALIEQHNVAICVQLCGFVEGEDKKCASYYSDKVggvlrfRNY
. ... . .. .|||... |. .. . | .|...| . | |. ..| | | | .|| || |. .. . |
vflitidgdpssdyinaali..............dsykrpaafivtqgPlqetvkdfWrlvydencasivmltelvevgrvkClkyWPedt......evy
SlktiDIKTDLAEFTDKKDFTLYTVEITNYRKNKgEQKKTVDILLYSAWPEHGAPQEAYPALEILKFCETYKK----NVLVHCSEGVGRTGTLVAIKYGI
||| | | . .... . ... ... |....| . . .||.|. |..| |.... .. .. ...|||| | ||||| .||. .
g....dikvelvetellaelvvrifrveklargq.eeirevrqfqflgWpdhdvPvsatgllklvrrvkksqeeeaGrivvhCsaGaGrtGtfiaidivl
DLCLKKKVTQIIDIILPVRQCRHGAVQDDTQVTYILL
|. ...| . .. .|. . |. | ..|
dmieregvvdvfnavktlrsrkvnmveteeqykfiyd
|
|||||||||
| subfamily_PTPN1_pd | Subfamily PTPN1 | 819-1049 | 5.6e-19 | 62.9 | In-house | 51-271 (290) | alignment | ||
Range on Protein: 819-1049
Range on HMM: 51-271/290.0
LEGFKNPFINANVMMFGKI--EWIMAQGPMdgtekkkdetdkpkRSTCEKHWALIEQHNVAICVQLCGFVEGEDKKCASYYSDKVGgvlrFRNYSLKTID
|| .| .|||... . .. ..|..|||. .|.. | .. ... | | .|| | |||.|. . .. |. .
leradndyinaslveleeakrsyiltqGPl..............pntvdhfWqmvWeqkskavvmlnkvvekeqikcaqywPqgee....ekellledtk
IKTDLAEFTDKKDFTLYTVEITNyrkNKGEQKKTVDILLYSAWPEHGAPQEAYPALEILKFCET------YKKNVLVHCSEGVGRTGTLVAIKYGIDLCL
.| .| . .|. .|. ..|..| | .. ... | .||. | |. |. | . . ...||| |.||.||.. . . |
lkvkliseerksyytvrllelen...lktqetreilhfhyttwpdfgvpespaaflkflfkvresGslssdvGpavihcsaGiGrsGtfclvdtclvlie
KKKV---TQIIDIILPVRQCRHGAVQDDTQVTYILLCVTKGL
||. .| . .| .|. |.| .| |. . | . .|
kkddlssvdikkvllelrkyrlGliqtadqlrfsylaileGa
|
|||||||||
| subfamily_Cele-PTP-1_pd | Subfamily Cele-PTP-1 | 822-1078 | 7.9e-25 | 82.6 | In-house | 44-269 (290) | alignment | ||
Range on Protein: 822-1078
Range on HMM: 44-269/290.0
FKNPFINANVMMF-GKIEWIMAQGPMDGTekkkdetDKPKRSTCEKHWALIEQHNVAICVQLCGFVEGEDK----KCASYYSDKVGGVLRFRNYSLKTid
|.. .| || . . .. |. | | . . . || ||.| .. | .| |.|| | | . . || |. ..||. |.| . ..|
fnddyiHAnrvtcpnglrliltqsPqeki.......tekrnStiekfwwmakqEkvkqvVmlcefeeksantslfaCakYvpesvgeelkfkgltvkC..
iktdlAEFTDKKDFTLYTVEITnYrknKGEQKKTVDILLYSAWPEHGAPQEAYPALEILKFCETYKKNVLVHCSEGVGRTGTLVAIKYGIDLCL-KKKVT
. ..|. ..... . .|.. ||. |.. | . .... .|..... ...| |.||| .|. | .| ||. | . ... .
.....kskekeddvetRelvvk.f...ddeeeftvtHsllkgWnklnvqedtktllsliqkvkasktpvivHcvdGiSrsAalaaiilgyQkiaetsgsv
QIIDIILPVRQCRHGAVQDDTQVTYILLCVTkglmekmpvpylrsfdavqYYHKQLLNNFYHP
.. |.. .|. | |...... .... . . .. |..|...
kledvlkalrkqralaitsalelafvdagiv...................llaievldqfaee
|
|||||||||
| subfamily_PTPRB_pd | Subfamily PTPRB | 824-1052 | 1.6e-26 | 88.0 | In-house | 79-288 (293) | alignment | ||
Range on Protein: 824-1052
Range on HMM: 79-288/293.0
NPFINANVMM--FGKIEWIMAQGPMDGtekkkdetdkpkrsTCEKHWALIEQHNVAICVQLCGFVEGEDKKCASYYSDKvggvlrfrNYSLKTIDIKTDL
. .|||| . . |.| .|||. . | .. | .. .... | | | ||. .|| |. .. . . ||| .|
sDYinanyipgynsprefiatqGPlpe..............tvddfWrmvwekkssiivmltqlvekgkvkCeeYWPad........eepvlyGdikvtl
AEFTDKKDFTLYTVEITNyrknkGEQKKTVDILLYSAWPEHGAPQEAYPALEILKFCETYK------KNVLVHCSEGVGRTGTLVAIKYGIDLCLKKKVT
. ....|... ...|.. ......| . . .||.|| |... . |.... .... . ..|||| |||||||..|.. .. .. .
vaeeeledwvirelkiek.....ekeerkvrqyhftsWpdhgvPektktlldfvrtvreaiektaskrPivvhCsaGvGRtGtfialdrllqaieeedyv
QIIDIILPVRQCRHGAVQDDTQVTYILLCVTKGLMEK
.|. |. .|. | || .| .| || . |..|
difgivaelReeRnllvqtekqYifihqcvldllrkk
|
|||||||||
| 0049772 | (Phosphotyrosine protein) phosphatases II | 824-1038 | 2.6e-15 | 52.4 | In-house | 72-269 (314) | alignment | ||
Range on Protein: 824-1038
Range on HMM: 72-269/314.0
NPFINANVMMFGkIEWIMAQGPMDgtekkkdetdkpkrSTCEKH----------WALI--EQHNVAICVQ---------------------LCGFVEGEd
.|||. . .| .|||.. |.. | .. ...|| . | |... ..
sdyinasyvdgf.lkfIatqgple..............itvvdfreepvlyyngwrmvlrgdlnvrdivmsrdevladelsrLdaAlgKtpllildgng.
kkcaSYYSDKVGGVLRfrnyslktidiktdlAEFTDKKDFtlytveitnyrknkgeqKKTVDILLYSAWPEHGAPQEAYpALEILKFCET--YKKNVLVH
.... . |. | .|...| .... .|. .| ..|| ... .|.|.|.|. ...||||
....neptaadlellk...............eelydpelf.................erlgikylripvpDgsaplled.fdeflefieeadkggpvlvH
CSEGVGRTGTLVAIKYgidLCLKKKVtQIIDIILPVRQCRH-----GAVQDDTQV
|. |.|||||.|.. | |... .| . ... ||..|. |... |
CkaGkgRtgtfvvaay...lmkllgv.sleealedvrlkRpinpnpgfieqleqy
|
|||||||||
| subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 825-1044 | 1.5e-25 | 84.7 | In-house | 49-259 (270) | alignment | ||
Range on Protein: 825-1044
Range on HMM: 49-259/270.0
PFINANVMMfgkiewimaqgPMDGTEKKKDETDKPKRSTCEKHWALIEQHNVAICVQLCGFVEGEDKKCASYYSDKVGGVLRFRNYSLKTIDIKTdlaef
.|||| . .|| .|| . |. .| ...| .| ...| | . |..| |||. |.. ... ..... .|.. ...
aYinAnyvr...........GfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpaepkekvkledgkikvlalse.....
TDKKDFTLYTVEITnyrkNKGEQKKTVdILLYSAWPEHGAPQEAY------PALEILKFC----ETYKKN--VLVHCSEGVGRTGTLVAIKYGIDLCLKK
. .. . | .... .|||... | | .||.||.|.|. |..|. . .|. .|||||.||||||||.|. ... | ..
ekeegyiltrlrle....ekgeerrlv.HfwyntWpdhgvpreedsslstdqllkmlravrrsekeldkaePllvHcsaGvgRtGtlialDiavrlLeet
KVTQIIDIILPVRQCRHGAVQDDTQVTYILLC
| ... || .|. | || |....
kkvdvlaiieelRkdRmalvqhpeqyeflyka
|
|||||||||
| subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 826-967 | 7.9e-10 | 33.1 | In-house | 61-182 (297) | alignment | ||
Range on Protein: 826-967
Range on HMM: 61-182/297.0
FINANVMMFG----KIEWIMAQGPMDgtekkkdetdkpkrSTCEKHWALIEQHNVAICVQLCGFVEGEDKKCASYYSDKVGGVLRFRNYSLKTidiktdL
.|||. ..| .. .|.||||.. .| . .| |. ...| . | .. . |. .||| |. . |.. |. .. .. |
yinadyvvfpdeeadlkyilaqGpls..............atvddfwtlvaeqdvrvivmvaklqedGrdkcapywpsvvqerlkagdvvvef......l
AEFTDKKDfTLYTVEITNYRKnkgEQKKTVDILLYSAWPEHGAPQE
....|. | ... |.. . . .... | . .||.|| | .
sstsdefd.rviltelqliyr...sesrvvrhvqflswpdhGvpsd
|
|||||||||
| subfamily_PTPN12_pd | Subfamily PTPN12 | 827-1052 | 5.9e-32 | 105.7 | In-house | 71-280 (290) | alignment | ||
Range on Protein: 827-1052
Range on HMM: 71-280/290.0
INANVMM--FGKIEWIMAQGPMdgtekkkdetdkpkRSTCEKHWALIEQHNVAICVQLCGFVEGEDKKCASYYSDKVGGVLRFRNYSLKTIDiktdlaEF
||||.. ||.|.| ||||. | . .| .| ..|| | | .| || . |||. |...... |.| ........ |
inanfikgvegkleyiaaqgPL..............pktlddfWrmiweknveivvmaCrevelgkkkCerYWpeegeeelefgefevtlee......ek
TDKKDFTLYTVEITNYrknkgEQKKTVDILLYSAWPEHGAPQEAYPALEILKFCETYKK----NVLVHCSEGVGRTGTLVAIKYGIDLCLKKKV---TQI
. ..||.. |..... .....| . | |||.|| |. | . ||... ..... ..|||| |||||||..|| | .| ..|. ..
avdddflirtLkveaq.....kesrkvyqfhYtaWPDhgvPssaksllelielvrelqesedaPlvvhCsaGvGrtGtiiaidyvrellkaekipeeldv
IDIILPVRQCRHGAVQDDTQVTYILLCVTKGLMEK
|..| .|. |. .|| | ... .|.. . ..
fdlvlelrkqraalvqtkeqyelvykavaelvqke
|
|||||||||
| subfamily_Cele-PTP-19_pd | Subfamily Cele-PTP-19 | 828-1044 | 1.2e-23 | 78.3 | In-house | 66-276 (301) | alignment | ||
Range on Protein: 828-1044
Range on HMM: 66-276/301.0
NANVMMFGKIE-----WIMAQgpmdGTEKKKDETDKPKRSTCEKHWALIEQHNVAICVQLCGFVEGEDKKCASYYSDKVGGVLRFRNYSLKTIDIKTDLA
.|. || || .. | .. | | ..|.| ||.. |..| | |. .|| . .||..|.. |.. |. ...|. . .. |
avevivdGkrvPihanwipts....GhphrfiatqgPlkntsedfwamlvqydvekivmlgqkvekleekceeylpvkisekldigrfkikiknkeliln
EFTDKKdftlyTVEITNYRknKGEQKKTVDILLYSAWPEHGAPQEAYPALEILKFCETYKKNVLVHCSEGVGRTGTLVAIKYGIDLCLKKKVTQIIDIIL
. . |. |.|... . . .|| || |...| |. ..... .| ..||||.|.||. .... .| . .. .. . .
kkiskr.....tlevedst..gkfatrtvthyqysewtdrgvPkshaelfdlmelvkksekPivvhcsaGiGrsvafigteylareveadptieltealk
PVRQCRHGAVQDDTQVTYILLC
.|. | .|| .|. .. |
hlrehrwngvqtnsqlywmtlG
|
|||||||||
| 0043147 | (Phosphotyrosine protein) phosphatases II | 838-1042 | 2.4e-22 | 74.9 | In-house | 21-154 (172) | alignment | ||
Range on Protein: 838-1042
Range on HMM: 21-154/172.0
EWIMAQGPmdgtekkkdetdkpKRSTCEKHWALIEQHNVAICVQLCGFvegedkkcasyysdkvggvlrfrnyslktidiktdlaeftdkkdftlytvei
..|. ||| |.|....|... .... . | |...
rfiatqgp..............lrntladfwrmlkelgithivnltel....................................................
tnyRKNKGEQKKTVDILLYSAWPEHGAPqEAYPALEILKFCET-----YKKNVLVHCSEGVGRTGTLVAIKYGIdlclkkK-VtQIIDIILPVRQCRHGA
... .... .|| || ||.| . ||.|.|... .. |||||| ||||||||||. . . . . . ... ||..| ||
...lydpellerlgiqylylpwpDhgvp.llellleflefidellalspggpvlVHCsaGvgRtgtlvaaylml......lgl.sleeavalvrekRpga
VQDDTQVTYIL
|| . | ...
vqnpsqyrfly
|
|||||||||
| 0051082 | (Phosphotyrosine protein) phosphatases II | 839-1044 | 6.4e-17 | 57.0 | In-house | 15-148 (151) | alignment | ||
Range on Protein: 839-1044
Range on HMM: 15-148/151.0
WIMAQGPMDgtekkkdetdkpkrstceKHWALIEQHNVAICVQLCGFVEGEdkKCASYYSDKVggvlrfrnyslktidiktdlaeftdkkdftlytveit
. .||.. ...|...... | |.. .| . .|..|. .
lyrsggpla..................dflellkelgiktivnlrseeerg..ycpeylpelg.....................................
nyrknkgeqkKTVDILLYSAWPEHGAPQEAYPALEILKFCETY-KKNVLVHCSEGVGRTGTLVAIKYGIdLClkkkvTQIIDIILPVRQCRHGAVQDDTQ
.| . . ||..| |. .||.|.... ...|||||| |.||||||||. . | . ... .|..|.|.|| .|
..........ievlhipildwpdpglplsfdavleflellldkkngpvlvHCsaGkgRTGtlvalylml.lg.....vsleealeeyrlkrpgvvqpnqq
VTYILLC
..|..
flfqlfa
|
|||||||||
| 0036282 | (Phosphotyrosine protein) phosphatases II | 840-1042 | 1.4e-23 | 78.9 | In-house | 20-163 (174) | alignment | ||
Range on Protein: 840-1042
Range on HMM: 20-163/174.0
IMAQGPMDgtekkkdetdkpkrstcekHWALIEQHNVAICVQLCGFVEGEDKKCASYYSDkvggvlrfrnyslktidiktdlaeftdkkdftlytveitn
| |||.. .|... .... . |.|. .| . || |...
iagqgpla...................fwemlkelgittvvmlleekelglykcinywpe........................................
yrkNKGEQKKTVDILLYSAWPEHGAPQEAYpALEILKFCETY-----KKNVLVHCSEGVGRTGTLVAIKYGIDLCLkKKVTQIIDIILPVRQCRHGAVQD
.. .... .|| || ||.| . ||..||.|.. .. |||||| ||||||||||. . . . | .. ...|.. .|..|.|.||
...lredlerlgiqylylpwpDhgvpdlsi.llefvkfveealsedpggpvlVHCsaGvgRtGtlvaaylmlrgll.eslvdaldlvrelRlqrpgmvqt
DTQVTYIL
. | ..
psQyrfly
|
|||||||||
| subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 846-1042 | 6.3e-19 | 63.1 | In-house | 40-232 (237) | alignment | ||
Range on Protein: 846-1042
Range on HMM: 40-232/237.0
MDGTEKKKDETDKPKRSTCEKHWALIEQHNVAICVQLCGFVEGEDKKCASYYSDKVggvlRFRNYSLKTIDIKTDlAEFTdkkDFTLYTVEITNYRKNKg
.||| || .. | |.|. | .. | . .. | | |..||...|| |. . . . | |. .| . ||. |.|. .. ... . |
fdgtpkkyiaaqgplesscddfwqmvwqekcsvivmltgliegnelkchkywpstd....qpaaygvltvslkkk.eefs...dytvrslllskrltlk.
eQKKTVDILLYSAWPEHGAPQEAYPALEILKFCETYK------KNVLVHCSEGVGRTGTLVAIKYGIDLCLKKKVTQIIDIILPVRQCRHGAVQDDTQVT
. . . ...||..| ||.. | . | ..||| |||||| .. | . . .||| .| . . . . | .| |
.evrlihqyqftswpdrgvpqqtaallrfrkniinrsphvsesgpwiihcsagvgrtgiflvidamlrqakekkvvdiynyvysieedrpyiiqtkdqyv
YIL
.|
fih
|
|||||||||
| subfamily_PTPN9_pd | Subfamily PTPN9 | 846-1045 | 1.7e-16 | 55.2 | In-house | 78-286 (297) | alignment | ||
Range on Protein: 846-1045
Range on HMM: 78-286/297.0
MDGTEKKKD--ETDKPKRSTCEKHWALIEQHNVAICVQLCGFVEGEDKKCASYYSDKVGGVLRFRNYSLKTIDIKTdlaeftdKKDFTLYTVEITNYRKn
.|| ..|| | | . |.. .| .. ...| . | .|| ||. |. .. . . .| ..|........ ..|.. ..||.| ..
vdGykqkkafiatqGplkktvsdfWrmvWeqevlvivmttrvvergrlkcgqyWpleeessaefgdlsvsnvevee.......eedykvrvleiknvkt.
kgEQKKTVDILLYSAWPEHGAPQEAYPALEILKFCETYK-----------------KNVLVHCSEGVGRTGTLVAIKYGIDLCLKKKVTQIIDIILPVRQ
|....| . .||..| |..| |..|. .. ..|||| |.|||||.... . .. .. . .... . .|.
..eesrkvthfqflsWPdyGvPssaaslldvlekvrekqalavkelgdewkghpsgPPivvhcsaGiGrtGtfitldiclsrleevgtvdvvetvkllrt
CRHGAVQDDTQVTYILLCV
| ..| . | .. |.|
qrafsiqtpeqyefcylav
|
|||||||||
| subfamily_Cele-PTP-9_pd | Subfamily Cele-PTP-9 | 848-1045 | 1.2e-20 | 68.7 | In-house | 24-217 (255) | alignment | ||
Range on Protein: 848-1045
Range on HMM: 24-217/255.0
GTEKKKDETDKPKRS-TCEKHWALIEQHNVAICVQLCGFVEGEDKKCASYYSDKVGGVLRFRNYSLKTIDiktdlaeftDKKDFTLYTVEITNYRKNKgE
. . .||. | | | .| . | | . | || | | . .|| ||. . . |.. . .. | . | | |.||| . .|
hvkPekdkkrknlysltvdkfyqtivqtktevvvmlcdfaeegvekcssyfplekdeklkladvnvtttk.........ssadvvlrtleitstlgek.k
QKKTVDILLYSAWPEHGAPQEAYPALEILKFCETYkKNVLVHCSEGVGRTGTLVAIKYGID---LCLKKKVTQIID---IILPVRQCRHGAVQDDTQVTY
. .|| | |.|. ||..| |.||| | |.||||.|.||. ..| . . . |.. | .| .. .|. |..|... |...
kthtvkhysykGWieknaPelareilnilkvvrds.ksvvvhCstGiGrsaafvlaelvyqkmirsldttetveldylslleelrskrkraihtPlqlaf
ILLCV
.| |
silmv
|
|||||||||
| subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 848-1045 | 2e-20 | 68.1 | In-house | 84-276 (318) | alignment | ||
Range on Protein: 848-1045
Range on HMM: 84-276/318.0
GTEKKKD--ETDKPKRSTCEKHWALIEQHNVAICVQLCGFVEGEDKKCASYYSDKvggvlRFRNYSlktiDIKTDLAEFTDKKDFTLYTVEITNyrkNKG
| ..|| . | |.| | .. . | |. | | .| .|.. |. .| |.| ... .| | .. .|..| ....|. ..
GyrrkkayiaaqaPlpetieDfWrmvWeqnsavivmltqeeergkakvhryWPsk.....gsrsyg....klvvelkeevelsdyvlrefkvtr...tee
EQKKTVDILLYSAWPEHGAPQEAYPALEILKFCETYK-----KNVLVHCSEGVGRTGTLVAIKYGIDLCLKKKVTQIIDIILPVRQCRHGAVQDDTQVTY
|....| | .||..| |... |.... .... . ..|||| ||||||. .|.. .. . .. . ... .|. | || . | ..
eesrqvrqyhytsWpdegvpesgaslldlvrqvskaqqksgagpivvhCsaGvGrtGvfiavdillerikaealvDvfqtvkqlreqrnlmvqtedqyef
ILLCV
| .
iydvl
|
|||||||||
| subfamily_Sponge-PTP9_pd | Subfamily Sponge-PTP9 | 848-1045 | 4.6e-16 | 53.4 | In-house | 80-289 (301) | alignment | ||
Range on Protein: 848-1045
Range on HMM: 80-289/301.0
GTE--KKKDETDKPKRSTCEKHWALIEQHNVAICVQLCGFVEGEDKKCASYYSDKVGGVLRFRNYSLKTIDiKTDLAEFTDKKdFTLYTVEITN--Y--R
|. || .. | ..| | || |. .. | ... || .|| |... .| . . . .. .. . .|. .. ... . .| | |
gysekkkfiaaqgpmkktlvdfWrliwqekpvsivmvtnlkegtkskceqywpnseaeseefgpftvtlvn.eqvyPdfvirq.lnvkiqdgsnngyier
K-NKGEQKKTVDILL--YSAWPEHGAPQEAYPALEIL-----KFCETYKKNVLVHCSEGVGRTGTLVAIKYGIDLCLKKKVTQIIDIILPVRQCRHGAVQ
| .. ..|.. |.| ||..| .| |... . . |.||||..|.|.|. ... |.. | | ..... ||. . |||.
kfkvksdksswdvlqlqvtdWpqdGvvreprtvLqviddvihrqqkigggpvvVHCSdtVsrsGvYcsvsiglEQckaegVVdvfqvtkavrrskpgaVt
DDTQVTYILLCV
| | | .
TLeqytsiydvi
|
|||||||||
| subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 848-1046 | 4.5e-15 | 50.5 | In-house | 48-237 (239) | alignment | ||
Range on Protein: 848-1046
Range on HMM: 48-237/239.0
GTEKKKDETDKPKRSTCEKHWALIEQHNVAICVQLCGFVEGEDKKCASYYSDKVGGVLRFRNyslktIDIKTDLaeFTdkkDFTLYTVEITNYRKNkgEq
|. | |. .. | .. | .. | | |..|| ||| |. | .| ||.. |. |. . |. ... . |
gspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpdstskycnlrv.....tlrktev..fa...dyiirtfvmsqvgqt..e.
KKTVDILLYSAWPEHGAPQEAYPALE----ILKFCETYKKNVLVHCSEGVGRTGTLVAIKYGIDLCLKKKVTQIIDIILPVRQCRHGAVQDDTQVTYILL
.. | .. ||..| || | | | | . ..||| ||||||... | . . |.| .|.. . .|. | || | .| |
eryvyqyhftvwpdkgvpqyatavlglrrkitkdslpgarpwvihcsagvgrtgaflvidamlrqakkqktvdifnyvkairedrphmvqtseqyvfihl
CVT
.|
avl
|
|||||||||
| subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 848-1045 | 5.5e-15 | 50.2 | In-house | 49-237 (239) | alignment | ||
Range on Protein: 848-1045
Range on HMM: 49-237/239.0
GTEKKKDETDKPKRSTCEKHWALIEQHNVAICVQLCGFVEGEDKKCASYYSDKVGGVLRFRNyslktIDIKTDLaeFTdkkDFTLYTVEITNYRKNkgEq
|. | |. .. | .. | .. | | |..|| ||| |. | .| ||.. |. |. . |. ... . |
gspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpdstskycnlrv.....tlrktev..fa...dyiirtfvmsqvgqt..e.
KKTVDILLYSAWPEHGAPQEAYPALE----ILKFCETYKKNVLVHCSEGVGRTGTLVAIKYGIDLCLKKKVTQIIDIILPVRQCRHGAVQDDTQVTYILL
.. | .. ||..| || | | | | . ..||| ||||||... | . . |.| .|.. . .|. | || | .| |
eryvyqyhftvwpdkgvpqyatavlglrrkitkdslpgarpwvihcsagvgrtgaflvidamlrqakkqktvdifnyvkairedrphmvqtseqyvfihl
CV
.|
av
|
|||||||||
| subfamily_Cele-PTP-6_pd | Subfamily Cele-PTP-6 | 851-1050 | 8.9e-27 | 88.9 | In-house | 82-278 (307) | alignment | ||
Range on Protein: 851-1050
Range on HMM: 82-278/307.0
KKKDETDKPKRSTCEKHWALIEQHNVAICVQLCGFVEGEDKKCASYYSDKVGGVLRFRNYSlKTIDIKTDLAEFTdKKDFtlYTVEITNYRKNKGEQKKT
|| .. |. .| . ||.. |..| . || .| || |. . | | | . . .|| .. |. | ...|. . . ... .|
kkficaqgplentqysfwamaiqekvesvimlckvielakikceqywpleegqklvfgeap.ntisvanlgakkl.apde..dlinvttlkvdwaqksrt
VDILLYSAWPEHGAPQEAYPALEILKFCETYKKNVLVHCSEGVGRTGTLVAIKYGIDLCLKK-KVTQIIDIILPVRQCRHGAVQDDTQVTYILLCVTKGL
.. | .. ||..|.|| |...|. . . |.|||| ||||.||.||| . | .. .. ... .|. || |.|.. | |. . . .
iqhlqwenwpdrgvpqinltainlleavrydtnpvvvhcsaGvGrsGtivaislvqdkmiaGinckdmkklveelrsqrhyaiqteaqylylhrvlleyf
M
.
l
|
|||||||||
| subfamily_Cele-PTP-10_pd | Subfamily Cele-PTP-10 | 851-1053 | 3.4e-22 | 73.4 | In-house | 96-293 (305) | alignment | ||
Range on Protein: 851-1053
Range on HMM: 96-293/305.0
KKKDETDKPKRSTCEKHWALIEQHNVAICVQLCGFVEGEDKKCASYYSDKVGGVLRFRNYSLktIDIKTDLAEFTDKKDFTLYTVEITnYrknKGEQKKT
|. .. | | .. | .. |..| | || || ||| |. | | ... . .. . . . . ....| | |.|| .
krficaqgpldqtidefwwmviqnkveqivmlcktvelgklkcaqywpaaqgeklelksgiv..venvsgskpmerdaeiqitllnlt.y...sgdqkms
VDILLYSAWPEHGAPQEAYPALEILKFCETYKKNVLVHCSEGVGRTGTLVAIKYGIDL-CLKKKVTQIIDIILPVRQCRHGAVQDDTQVTYILLCVTKGL
| | .. ||. | | .||.| | ..|||| |.|||||.|||.| .. . .|.. . ... .|. | ..|.| | .| . . .
vrhlqwtewpdrgvppckltslellsairgskvpivvhcsagigrtgtivaieyilekiaenkpcppmpelvkalrdqrafsiqndvqylfihrvmlnyf
MEKM
.||
leky
|
|||||||||
| subfamily_PTPN6_pd | Subfamily PTPN6 | 851-1046 | 4.2e-22 | 73.5 | In-house | 98-294 (306) | alignment | ||
Range on Protein: 851-1046
Range on HMM: 98-294/306.0
KKKDETDKPKRSTCEKHWALIEQHNVAICVQLCGFVEGEDKKCASYYSDKVGGVLrFRNYSLKTIDIKtdlaeftDKKDFTLYTVEITNYrkNKGEQKKT
|. |. ..| . | .. | | . | . || .||| |. |. . ..|..... | ...|..| .. ... .|......
ksyiatqgclettvsdFWrmvwqensrvivmttkevErgkekCarYWPdeeekee.yGkisvtnvsek.......sladYilRelsvskk..kkkkeere
VDILLYSAWPEHGAPQEAYPALEILKFCETYKKN--------VLVHCSEGVGRTGTLVAIKYGIDLCLKKKVTQIIDI---ILPVRQCRHGAVQDDTQVT
| . . .||.|| |.. . |. |. .. ... ..||||.|.|||||.. | ..| ||.. ||| . ||. | | || ..|
vfqyhfksWPdhgvpkdpgavLdfledvnrkqeeleeaeagpivvhCsaGiGRtGtfiviDillkliekkgldadidiqklvksvreqrsglvqteqqyk
YILLCVT
.. ..
fvykaik
|
|||||||||
| subfamily_hpo-7_pd | Subfamily hpo-7 | 852-1054 | 3.8e-19 | 63.6 | In-house | 31-232 (263) | alignment | ||
Range on Protein: 852-1054
Range on HMM: 31-232/263.0
KKDETDKPKR----STCEKHWALIEQHNVAICVQLCGFVEGEDKKCASYYSDKVGGVLRFRNYSLKTIDIKTdlaeftdkkDFTLYTVEITNYRKNKgEQ
.||. | | .| . |.| . | || | | . .|| ||. . . ... | .. | ... | | | |.... ..| .
ekdkkrknlysllvqtidkfyqtivqtktevvvmLcDfneegvekcssyfPlekdekqklanvnvcttkvqs.........dvllktlellstlgeK.kk
KKTVDILLYSAWPEHGAPQEAYPALEILKFCETYkKNVLVHCSEGVGRTGTLVAIKYGID---LCLKKKVTQIID---IILPVRQCRHGAVQDDTQVTYI
.|| | |.|. .|..| |.||| |.. ||||.|.||. . . . |.. | .| .. .|. |..|... |. .
thtvkhysykgWiekndpelareilnilkvarns.kslvvhcstGiGrsaafsvaElvyqkmirsldttstveldylsLleelrssrkraihtPmqLafs
LLCVTKGLMEKMP
.| | . ... ..
ilmvLdfvlnnfa
|
|||||||||
| subfamily_PTPN5_RR_pd | Subfamily PTPN5_RR | 854-1042 | 7.6e-25 | 82.5 | In-house | 76-261 (274) | alignment | ||
Range on Protein: 854-1042
Range on HMM: 76-261/274.0
DETDKPKRSTCEKHWALIEQHNVAICVQLCGFVEGEDKKCASYYSDKVGGVLrfrnySLKTIDIKTDLAEFTDKKDFTLYTVEITNYRKNKGeqkktVDI
| | .| . | .| |..| . | | . | . .||| |. |. . . | . .|.. . ....|... .. . . ... |
vatqGPlpntvadfWrmiyqeevqvivmltklkeaneqkCavyfPdaedyei.....serygdveikvekiverndysvrklvlkylerers.....vkh
LLYSAWPEHGAPQEAYPALEILKFCETYKK-------NVLVHCSEGVGRTGTLVAIKYGIDLCLKKKVTQIIDIILPVRQCRHGAVQDDTQVTYIL
.|..||.| .|..| . |.... |. .. |.|||| |.|||| .||. .. ...| .. |. .|. | | || . | .|
ywytdWPdhksPddantlldlvleveesreeenaklapvvvhCsaGiGrtGcfiaisiavrqlreeivvdvlkivcnlrldrGGmvqtseqyelih
|
|||||||||
| subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 855-1046 | 1.8e-25 | 84.5 | In-house | 94-276 (288) | alignment | ||
Range on Protein: 855-1046
Range on HMM: 94-276/288.0
ETDKPKRSTCEKHWALIEQHNVAICVQLCGFVEGEDKKCASYYSDKVggvlRFRNYSLKTIDiktdLAEFTDKKDFTLYTVEITnyrknKGEQKKTVDIL
| | .| .. | |. .... | | ..|||...|| |. |. . .|| |. | | ...||.| .... | ... .. .
atqgPladtvndfWelvyenktstivmltelveggktkCeeYWPdad....kpknyGsvtvt....lveskeledfvlrkllle.....kkkteleitqy
LYSAWPEHGAPQEAYPALEILKFCETYK----KNVLVHCSEGVGRTGTLVAIKYGIDLCLKKKVTQIIDIILPVRQCRHGAVQDDTQVTYILLCVT
| |||.|| |. . | ||.|. .. . ....||||.||||||| .|.. || .... ..... .|. | || .| .| ..
qylaWpdhgvPeskapllellrqvkvanqadtgpiivhCsaGvGrtgtFialdalidaveeedyiDvagtvaklRkqRallvqtlkqYefiyevll
|
|||||||||
| subfamily_PTPRG_pd | Subfamily PTPRG | 855-1042 | 1.7e-22 | 74.4 | In-house | 95-280 (563) | alignment | ||
Range on Protein: 855-1042
Range on HMM: 95-280/563.0
ETDKPKRSTCEKHWALIEQHNVAICVQLCGFVEGEDKKCASYYSDkvGGVLRFRNYSLKTIDIKTdLAEFTDKkdftlyTVEITNYRKNKG---EQKKTV
| .| ..|.. | .| ..|||| | . .|| . .|| |. ..... . ... |. .. || | . |. | | ...|. ...|.|
atqgplkdtfddFWrmiWeqnvaiivmitnlvergrrkcdvYWPk..desetygalqvtlieeev.lalytvr......tlviknlklkkkkqcdteklv
DILLYSAWPEHGAPQEAYPALEILKFCETYKKN----VLVHCSEGVGRTGTLVAIKYGIDLCLKKKVTQIIDIILPVRQCRHGAVQDDTQVTYIL
|. ||.||.|. . | | | .. .|. ..||||.|||||||..... . .... .. ... .| | ||. | ...
rqyhytkWPdhgvPehslpvLifvkkssaankaeaGPivvHcsaGvgrtGtyivldtllkqiqqenavnvfgflkhiraqRnflvqteEqYiflh
|
|||||||||
| subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 855-1043 | 8.2e-21 | 69.4 | In-house | 95-277 (319) | alignment | ||
Range on Protein: 855-1043
Range on HMM: 95-277/319.0
ETDKPKRSTCEKHWALIEQHNVAICVQLCGFVEGEDKKCASYYSDKvggvlRFRNYSLKTIDIKtdlaEFTDKKDFTLYTVEItNYRKNKGEQkKTVDIL
| |. | | | .. .... | | |.. || . |. |.... | .| ..... | ..|. ... | .... | ..|
atqaPlentiedfWrmvWeeessivvmltklveklkvklkkywpee.....nfeeyGrlivtle....eeeeledyiirklkl.nkkssevet.Revkhf
LYSAWPEHGAPQEAYPALEILKFCETYKKN-----VLVHCSEGVGRTGTLVAIKYGIDLCLKKKVTQIIDIILPVRQCRHGAVQDDTQVTYILL
| .||.|. |..| |..|| . ... . ||||.||||||| .... .. . | . .. .| | || | ..|
qyteWpdhdvPekatslldllkrirksrektqsgPivvhCsaGvGRtGtfivldamlervkeegvlDvfstvsrlRtqRnimvqrpeqYkfiye
|
|||||||||
| subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 855-1050 | 8.1e-19 | 62.9 | In-house | 96-285 (297) | alignment | ||
Range on Protein: 855-1050
Range on HMM: 96-285/297.0
ETDKPKRSTCEKHWALIEQHNVAICVQLCGFVEGeDKKCASYYSDKvgGVLRFRNYSLKTIDIktdlaefTDKKDFTLYTVEITnyrKNKGEQKKTVDIL
|..|...| . ||.. ...|.. | | |. ||||| |.||| || | . |... . .... | ..|.| |.| ... |.
ttqmPmkatvadfWamvldeqvstivmlnddner.dkkcaryWsdk..gvttfGdvsvvllsv.......sereGfikrelevt...kgkakarrvvkqy
LYSAWPEHGAPQ-EAYPA-LEIL----KFCETYKK-NVLVHCSEGVGRTGTLVAIKYGIDLCLKKKVTQIIDIILPVRQCRHGAVQDDTQVTYILLCVTK
. ||.. .. . .. |... | .. .. .||||. |||||| |..|. . ..| .| ... .|| | || . | ... | .
qfveWPdkaverkdsassllklisevrkdfsqnaegPllvhclaGvGrtgvlltidsvvaeakrekevdifglvkklrqerpylvqtkeqykfvyvavle
GLM
|.
all
|
|||||||||
| subfamily_PTPRN_pd | Subfamily PTPRN | 855-1047 | 1.4e-16 | 55.0 | In-house | 104-290 (297) | alignment | ||
Range on Protein: 855-1047
Range on HMM: 104-290/297.0
ETDKPKRSTCEKHWALIEQHNVAICVQLCGFVEGEDKKCASYYSDKVGGVlrFRNYSLKTIdiktdlAEFTDKKDFTLYTVEITNYRKnkgEQKKTVDIL
|. | || . | .. .. |.. |.|. | . |.|. |. |. | . | .. . .| .|. . . . | .. .. .|| .
atqgplastvadfwqmvweqGvvvivnltrleeegvkqckrywpdeGsev..yhiyevhlv......sehiwcddylvrsfylknlqt...setrtvtqf
LYSAWPEHGAPQEAYPALEIL-KFCETYK---KNVLVHCSEGVGRTGTLVAIKYGIDLCLKK-KVTQIIDIILPVRQCRHGAVQDDTQVTYILLCVTK
. .|||.|.| .| . || | .|. ..||||.|.||||. ..| .. || | .|. . .|. |.| |. | ..| .|..
hflswpeegvPasaksllefrrkvnksyrGrscpivvhcsdGaGrtGvyilidlvlnrllkGvkeidiaatlehlrdqrpglvktkdqfefaltavae
|
|||||||||
| subfamily_PTPN14_pd | Subfamily PTPN14 | 855-1044 | 5.1e-16 | 53.5 | In-house | 97-291 (300) | alignment | ||
Range on Protein: 855-1044
Range on HMM: 97-291/300.0
ETDKPKRSTCEKHWALIEQHNVAICVQLCGFVEGEDKKCASYYSDKVGgvlRFRNYSLKTIDIKTdlaEFTDKKDFtLYTVEITnYRKNKGEQKKTVDIL
. | . |....| .. ...|.. |.| |. .|. .|. .. . .. . . | .|... | . | .. . ....|| .|
vaqgPleltvqdfWqmvWeqgvqlivmlteeeedgkeksfkyfPkles...kkktvefgkfkvtt...kfsedsds.vittglk.lkhlpskeertvwhl
LYSAWPEHGAPQEAYPALEILKFCETYK-------------KNVLVHCSEGVGRTGTLVAIKYGIDLCLKKKVTQIIDIILPVRQCRHGAVQDDTQVTYI
| ||.|| |.. . |. |. . . ||||||.|||||| |. | . .. .| .. .|. | || .| ...
qytDWpdhgvPeDvkgflsyLeevqsvrrktnseveskeskPPvlvhCsaGvGrtGvlilsdlliatlehneeidikkvlarLreqrmllvqtlaqYkfv
LLC
Ykv
|
|||||||||
| subfamily_Urchin-PTP-4_pd | Subfamily Urchin-PTP-4 | 855-1066 | 8.6e-15 | 49.0 | In-house | 92-254 (392) | alignment | ||
Range on Protein: 855-1066
Range on HMM: 92-254/392.0
ETDKPKRSTCEKHWALIEQHNVAICVQLCGFVEGEdkkcasyysdkvggvlrfrnyslktidiktdlaeftdkkdftlytveitnyrknKGEQKKTVDIL
.. |. .. . | .. |.||. . . . ||. ||....||
asqgpnaaslddfwrmvfqenvttiamvtklkegd......................................................kgddartvaqf
LYSAWPEHGAPQEAYPALEILKFCE----TYKKNVLVHCSEGVGRTGTLVAIKYGIDLCLKKKVTQIIDIILPVRQCRHGAVQDDTQVTYILLCVTKGLM
.. ||... |. . |...| . | . ...||| |||||| ...| . . | .. ...... .|. | || . | ..| .| . |.
hftewPdkdvpkhtssllkfikevkadfGqythpliihcsagvgrtgvvisidsvvahakktrmvdvfnfvtnirrkrpymvqtkeqyafiygavledll
EK-MPVPYLRSFDAVQY
. .| .. | .|
wrntlipvvhftdhlqd
|
|||||||||
| subfamily_Sponge-PTP6_pd | Subfamily Sponge-PTP6 | 855-1045 | 1.2e-14 | 48.6 | In-house | 95-275 (439) | alignment | ||
Range on Protein: 855-1045
Range on HMM: 95-275/439.0
ETDKPKRSTCEKHWALIEQHNVAICVQLCGFVEGEDkkcasyysdkvggvlrFRNYSLKTI--DIKTDLAEFTDKKDFTLYTVEITNYRkNKGEQKKTVD
.|. ||. |... | |. ..... |.|. .|| . . ... || . .... . . | | ...|...||
atqgpkkettddfwrlviekktvtivmltnlvesyk................ywpsdaevcygdiavrvdrnielpnyvirgfkvfner.dttekertvl
ILLYSAWPEHGAPQEAYPALEILKFCETYK-----KNVLVHCSEGVGRTGTLVAIKYGIDLCLKKKVTQIIDIILPVRQCRHGAVQDDTQVTYILLCV
. | |||.. | .| |. |. .. . |.|||| |||||||..|. .. .. .| |. .|. |. ||. | .| .|
qfhyiawpdknvpaqashvldflrainsandkeeygpvvvhcsagvGrtGtiialdialeqlklenkvdikgivkvlrkqrkqmvqalcqyvfiynav
|
|||||||||
| subfamily_ptpA1_pd | Subfamily ptpA1 | 855-1001 | 4.9e-07 | 23.8 | In-house | 93-248 (418) | alignment | ||
Range on Protein: 855-1001
Range on HMM: 93-248/418.0
ETDKPKRSTCEKHWALIEQHNVAICVQLCGFVEGEDKKCASYYSDKVGGVlRFRNYSLKTIDIKTDLAEFTDKKDFTLYTVEITNYRKNKGEQKKTVDIL
|. | | | .. . . | | | | || |. ...|| .| | . | |. . . . | | . . .
ctqgplpntiadfwrmvwenrcriivmlsresencrikcdrywpeqigge.qfsiygngnevfgtysvelveviqdpereiitrnirltfegetrditqy
LYSAWPEHGAPQEAYPALEILKFCET--------YKKN--VLVHCSEGVGRTGTLVA
| ||.| |. . | ..|. .| ..|||| |||||||...
qyegwpdhnipdhtqpfrqllhsitnrqnqiipssdrnvpiivhcsagvgrtgtfct
|
|||||||||
| subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 856-1047 | 5.9e-26 | 86.0 | In-house | 96-281 (290) | alignment | ||
Range on Protein: 856-1047
Range on HMM: 96-281/290.0
TDKPKRSTCEKHWALIEQHNVAICVQLCGFVEGEDKKCASYYSDKvgGVLRFRNYSLKTidiktdLAEFTDKkDFTLYTVEITNYRKNkgEQKKTVDILL
|. | .| . | || |..|.| | |. .| . .|| |..|. .. .. ..|.| | | | . ... ..|..| ... ..|..| .
tqgpvsntlvdFWkliwqekvtiivmltniieegkvkCqqYWpds..dtkaygefsikl......lneetln.eyierklevknknsa..gakqsvtqyq
YSAWPEHGAPQEAYPALE-ILKFCE----TYKKNVLVHCSEGVGRTGTLVAIKYGIDLCLKKKVTQIIDIILPVRQCRHGAVQDDTQVTYILLCVTK
..|...| .. | | . . . .. ..||||..|||.....|.. .|. | .. | ...... |... | || |. .| | .
itnwdstgkvtnpqtillvieemyktqrkrgntsivvHCSdtvgrsavfcaaattinkcktegvidvfqvlksqRiqkpgsvqtvqqyqgifqivlt
|
|||||||||
| subfamily_PTPRD_pd | Subfamily PTPRD | 856-1045 | 8.2e-26 | 85.7 | In-house | 96-277 (564) | alignment | ||
Range on Protein: 856-1045
Range on HMM: 96-277/564.0
TDKPKRSTCEKHWALIEQHNVAICVQLCGFVEGEDKKCASYYSDKvGgVLrfrNYSlktiDIKTDLAEFTDKKDFTLYTVEItnyRKNKGEQKKTVDILL
| |. .|.| | .. ..|... | | .| . .||..|. .| | .| ... .| | ....|... | .. .|.| .....|
tqgPlaetiedFWRmvweqnsstiVmltkleEkgkvkchkYWPek.g.te...tyg....eltVtleeeeeladyeirtfkl...kkkkssesreVrqFh
YSAWPEHGAPQEAYPALEILKFCETYKK----NVLVHCSEGVGRTGTLVAIKYGIDLCLKKKVTQIIDIILPVRQCRHGAVQDDTQVTYILLCV
. .||.||.|..| . |.... ...... ..|||| ||||||| ..|.. .. ..|. | .. .|. | || .| .| .
FtsWPdhgvpesatslLdlirkvralnepdagPivVhCSaGVGRTGtfividamlerikeektvDiyqyvkalrkqRnamVqteeQYiFiheai
|
|||||||||
| subfamily_Cele-PTP-18_pd | Subfamily Cele-PTP-18 | 856-1042 | 7.9e-24 | 78.9 | In-house | 93-280 (305) | alignment | ||
Range on Protein: 856-1042
Range on HMM: 93-280/305.0
TDKPKRSTCEKHWALIEQHNVAICVQLCGFVEGEDKKCASYYSDKVGGVLRFRNYSLKtIDIKTDLAEFTDKKDFTLYTVEITNY-RKNKGEQKKTVDIL
|. | || | . |..| || ..| |||. |.. | . || |.. | | .| . .. . .. . .|. | . ||... |
tqaplektcadfwymclqdkveaifmlcnllekgakkcleyfaskdkdvlefeekgqk.isvkfessvtlkfrkdakakvtetvlviegpgekarkvthy
LYSAWPEHGAPQEAYPALEILKFCETYKKNVLVHCSEGVGRTGTLVAIKYGIDLCLKKKVTQ-IIDIILPVRQCRHGAVQDDTQVTYIL
. ||. | | ||.|. . . | . |||| |.||||..| ..| .| | .. . |. .|. | ..| |.| ..
hwidwpdrgvpaadlailellekarpskgpivvhcsagigrtgsvvmleyildqllagqiiedtdkilqkireqrnnsiqtdaqylfvh
|
|||||||||
| subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 856-1045 | 1.4e-23 | 78.3 | In-house | 91-274 (287) | alignment | ||
Range on Protein: 856-1045
Range on HMM: 91-274/287.0
TDKPKRSTCEKHWALIEQHNVAICVQLCGFVEGEDKKCASYYSDKVGgvLRFRNYSLKTIDIKtdlaeftDKKDFTLYTVEITNyrKNKGEQKKTVDILL
.. | .| . | ||...|| . | || | ....| |.... . . .|... .. . ..... ..|..| ||| ..|..|
aesPmfntarnfWkliddrnvtaivmlcqekendeevcyqyWpeeks..vvlGeyniellnee.......vnagyierklevkn..knkagdkqqvkqyq
YSAWPEHG-APQEAYPALEILKFCETYKK----NVLVHCSEGVGRTGTLVAIKYGIDLCLKKKVTQIIDIILPVRQCRHGAVQDDTQVTYILLCV
. .|...| .. . | | . | .| ..||||..|||.....|. .|. | . | ..... |. . |.|| .| ..| |
itnWdstgkvtepqtillvieemyktqrkrgntsivvhCsdtvGrsamfcaaattinkckteGviDvfqvlksqriqkpgsvqtveqykfindiv
|
|||||||||
| subfamily_Cele-PTP-11_pd | Subfamily Cele-PTP-11 | 856-1052 | 3.9e-23 | 76.6 | In-house | 87-279 (312) | alignment | ||
Range on Protein: 856-1052
Range on HMM: 87-279/312.0
TDKPKRSTCEKHWALIEQHNVAICVQLCGFVEGEDKKCASYYSDKVGGVlRFRNYSLKTiDIKTDLAEFTDKKDFTLYTVeITNYRKNKGEQKKtVDILL
|. | .|| . | | . . |||||| .||| | || || | . .. . | . |.. || . | . | |.. | ..
tqgplentcthfwqlalslgstsiillcgfvedgsekcakyisdivgfv.dledhrvyt.eycteieiggkskdkithrv.lkvvvkatgqesk.lnhyq
YSAWPEHGAPQEAYPALEILKFCETYKKNVLVHCSEGVGRTGTLVAIKYGIDLCLKKKVTQIIDIILPVRQCRHGAVQDDTQVTYILLCVTKGLMEK
...||.|| |. || .| || |. ||| ||||||||. |. | . . .. |. . .|. | .|. | | | || . |. |
waswpdhgmpdscdtalrllsavkkdkkpviahcsagvgrtgtlaliesmiaalrhprkqnvkdsfvllrkdrarsvrvfpqyvyalrcvleflysk
|
|||||||||
| subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 856-1066 | 1.1e-22 | 75.2 | In-house | 92-295 (315) | alignment | ||
Range on Protein: 856-1066
Range on HMM: 92-295/315.0
TDKPKRSTCEKHWALIEQHNVAICVQLCGFVEGEDKKCASYYSDKVGGVLRFRNYSLKTIDIKTDlAEFTDKKdftlytVeITnyrkNKGEQKKTVDILL
. |.... . | .. |..|. | . ||. ||. |. |. . .| ...........| .. . .| . .| |.|...||
sqgPlkasvddfwrmvlqekvttivmvtkkqegdkikcrqywPdrkadsvefGsikvellslead.tdgvark......l.vt....rkseesrtvtqfq
YSAWPEHGAPQEAYPALEILKFCE----TYKKNVLVHCSEGVGRTGTLVAIKYGIDLCLKKKVTQIIDIILPVRQCRHGAVQDDTQVTYILLCVTKGLM-
. ||..|..... |...| ... ..||||| |||||| ...|. .. .... . ... .|. | || . . ..| | . |.
ftewPdkGvdkqtssllklikevkadngkkefsllvhcsaGvGrtGvvisidevvaqikrtrsvdvfnfvknlrakrpylvqteeeyafiydavledllw
EKMPVPYLRSFDAVQY
. .. .. | .|
rntlilvihftdhlqd
|
|||||||||
| 0046846 | (Phosphotyrosine protein) phosphatases II | 856-1046 | 2.9e-22 | 74.7 | In-house | 28-170 (176) | alignment | ||
Range on Protein: 856-1046
Range on HMM: 28-170/176.0
TDKPKRSTCEKHWALIEQHNVAICVQLCGFVEGEDKKCASYYSDkvggV----Lrfrnyslktidiktdlaeftdkkdftlytveitnyrknkgeqkktv
|. | ..|... .... .... . | |. || . ||. |... . .
tqgplprtladflemlkelgitavvnlteevelgrlkcpnywpe....leklgi..............................................
dILLYSAWPEHGAPQEaYPALEILKFCETYK---KNVLVHCSEGVGRTGTLVAikygIDLCLKKKVTQIIDIILPVRQCRH-GAVQDDTQVTYILLCVT
|. ||.||.|. ||.|.|.... ..|||||| |.|||||||| ..|. ..| . ... ||..|. |||| . |. .. ..
.qylhlpwpDhgvpdl.elllellefirealkeggpvlVHCsaGigRtgtlva....ayllelekglsveealalvreqRplgavqtpeQyrflyefel
|
|||||||||
| 0049260 | (Phosphotyrosine protein) phosphatases II | 856-1042 | 5e-22 | 73.7 | In-house | 14-143 (152) | alignment | ||
Range on Protein: 856-1042
Range on HMM: 14-143/152.0
TDKPKRSTCEKHWALIEQHNVAICVQLCGFVEGEDKKCASYYsdkvggvlrfrnyslktidiktdlaeftdkkdftlytveitnyrknkgeqkktvdILL
| | . |....| .. .... . | |. ..| ||. |. |
tqgpgpntladfwrmlkelgittivmltellelgklkceqyi.......................................................qyl
YSAWPEHGAPQEAYPALEILKFC----ETYKKNVLVHCSEGVGRTGTLVAIKYGIdlclkkKVTQIIDIILPVRQCRHGAVQDDTQVTYIL
. || ||.|. . |..|.|. . ...|||||| ||||||||||. . . . . ... ||..| |||. | ...
hlpwpDhgvpdlsqlllflllfieklaldkggpvlVHCsaGvgRtgtlvaaylml......lgvsleeavalvrekRpgavpnpgqlrfly
|
|||||||||
| subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 856-1068 | 9.6e-22 | 71.7 | In-house | 91-296 (515) | alignment | ||
Range on Protein: 856-1068
Range on HMM: 91-296/515.0
TDKPKRSTCEKHWALIEQHNVAICVQLCGFVEGEDKKCASYYSDKVGGVLRFRNYSLKTIDIKTDlaefTdkkDFTLYTVEITnyrknKGEQKKTVDILL
. |.... . | |. |.||. . . ||. ||. |. || | ..| ....... .... | . . ..... ||.. .||
sqgPnkasvddfWrlvlqenvttiamvtklkegdkikcgkyWPdkpgdsvkfGsikvelvsleac....t...ggikrkltvl.....kgddsrtvtqfh
YSAWPEHGAPQEAYPALEILKFC----ETYKKNVLVHCSEGVGRTGTLVAIKYGIDLCLKKKVTQIIDIILPVRQCRHGAVQDDTQVTYILLCVTKGLM-
. ||..|.|... | ..| . |. ...||| |||||| ...|. . . .. . ... .|| | || . | ..| | |.
fteWPdkGvpkhtssllklikevkadhgqythpliihcsaGvGrtGvvisidsvvahakttrmvdvfnfvtnirqkrpylvqtqeqyafiygavledllw
EKMPVPYLRSFDAVQYYH
. .| . | .| |
rntlipvihftdhlqdlh
|
|||||||||
| subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 856-1047 | 1e-21 | 72.3 | In-house | 57-240 (250) | alignment | ||
Range on Protein: 856-1047
Range on HMM: 57-240/250.0
TDKPKRSTCEKHWALIEQHNVAICVQLCGFVEGEDKkCASYYS-DKVggvlrfRNYSlktiDIKTDLAEFTDKKDFTLYTVEITNYRKnkgEQKKTVDIL
| .| .| |. | .. ..... | | ..| | . . |. .| ..| |.. .| . . |.| .. .....| .....| |
tqgPlqatiedfWrmvleeksgtivmLtnLkesekt.yhqywPveka......ekyG....dvtvsllskeefadytkrklklskakk...aderivrql
LYSAWPEHGAPQEAYPALEILKFCETYKKN-----VLVHCSEGVGRTGTLVAIKYGIDLCLKKKVTQIIDIILPVRQCRHGAVQDDTQVTYILLCVTK
. .||. | |..| .||.|| .. ... |.|.||.||||.|. .||. .. |.|| . ..| .|. | .||. .| .. . |
hfvvWPdkgvPevatavLellkkvqasqqqagnaPvivqCsaGvgrsGafiaidavlerlkkekvvdvfkvikvlrkdrphavesleqyvfvyeiilk
|
|||||||||
| subfamily_PTPRA_pd | Subfamily PTPRA | 856-1044 | 1.3e-21 | 71.8 | In-house | 106-290 (330) | alignment | ||
Range on Protein: 856-1044
Range on HMM: 106-290/330.0
TDKPKRSTCEKHWALIEQHNVAICVQLCGFVEGEDKKCASYYSDKvgGVLRFRNyslktidIKTDLAEFTDKKDFTLYTVEITNYRKNK-GEQKKTVDIL
. ||. | | | .| ... | | | . | ...||| |. |. |.. . | |. . . | .|.|. . ... ... .... | .
aqGPkeetvedfwrmiweqksativmltelkerkeekcaqywPde..GlvtyGn.......irvevedetvlvdytvrkflvqqlpdatrekksrlvrqf
LYSAWPEHGAPQEAYPALEILKFCETYK----KNVLVHCSEGVGRTGTLVAIKYGIDLCLKKKVTQIIDIILPVRQCRHGAVQDDTQVTYILLC
. .||. | | |. |..|| .. . . |||| |||||||..... .. ... . ... .|. | || | | ..|
hftswPdvGvPfepiGmlkllkkvkklnqqsagpivvhcsaGvGrtGtfivldavlervkaerkvdvfefvkrlrlqrpqmvqtdeqyefiykv
|
|||||||||
| subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 856-1047 | 9.7e-21 | 69.4 | In-house | 109-289 (319) | alignment | ||
Range on Protein: 856-1047
Range on HMM: 109-289/319.0
TDKPKRSTCEKHWALIEQHNVAICVQLCgfvegeDKKCASYYSDKVggVLRFrnyslKTIDIKTDLAEFTDKkdFTLYTVEITNYRKNKGEQKktVDILL
. |. | . | .| ..|.. | | .||. |. |. | . . ..| |. | |.. ... .|... |.|. .| .
aqGPldntladfWrmiweyncstivllt......kdkcsqywplki..vike.....erfkvkvdsveetae..yvvrdielsedgkekdirk..itqfh
YSAWPEHGAPQEAYPALEILKF------CETYKKNVLVHCSEGVGRTGTLVAIKYGIDLCLKKKVTQIIDIILPVRQCRHGAVQDDTQVTYILLCVTK
. ||..| |. . . . ..| | ..|..|||| ||||||. .... .| ..| .. ... .|| | ||| .| .| . .
flGwpdvGvpdypsdlmrlvkkvrhltskenhranivvhcsaGvGrtGvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysalle
|
|||||||||
| subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 856-1047 | 1.4e-20 | 68.9 | In-house | 73-253 (284) | alignment | ||
Range on Protein: 856-1047
Range on HMM: 73-253/284.0
TDKPKRSTCEKHWALIEQHNVAICVQLCgfvegeDKKCASYYSDKVggVLRFrnyslKTIDIKTDLAEFTDKkdFTLYTVEITNYRKNKGEQKktVDILL
| |. | . | .| ..|.. | | ..||. |. |. | . . ..| |. | ... ... .|... |.|. .| .
tqGPldntladfWrmiweyncstivllt......kdkcsqywplki..vike.....erfkvkvdsveesee..yvvrdielsedgkekdirk..irqfh
YSAWPEHGAPQEAYPALEILKF------CETYKKNVLVHCSEGVGRTGTLVAIKYGIDLCLKKKVTQIIDIILPVRQCRHGAVQDDTQVTYILLCVTK
. ||..| |. . . . ..| | ..|..|||| ||||||. .... .| ..| .. ... .|| | ||| .| .| . .
flgwpdvgvpdypsdlmrlvkkvrhltskenhranivvhcsagvgrtgvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysalle
|
|||||||||
| subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 856-1042 | 7.2e-19 | 62.9 | In-house | 97-272 (315) | alignment | ||
Range on Protein: 856-1042
Range on HMM: 97-272/315.0
TDKPKRSTCEKHWALIEQHNVAICVQLCGFVEGEDKKCASYYSDKvggvlrfrN--YSLKTIDIKTDlaEFtdKKDFTLYTVeitnyRKNKGEQKKTVDI
. |. .. . | |. ..... | | . |||| .|. |. || . | |. | . | ....| |. |.. ..|
aqgpnvasvkdfwrlvfeedigkivmltnlvegekrkaekywpdk........kviyGkitvtrkse..ev..nteytvrtl.....svvfgdnirevvq
LLYSAWPEHGAPQEAYPALEILKFCETYKKN----VLVHCSEGVGRTGTLVAIKYGIDLCLKKKVTQIIDIILPVRQCRHGAVQDDTQVTYIL
| |..||. | |. . | ... . ...| ..||||.|||||||..... .| ... . ..| ||| | ..|| | .|
lhytswpdmgvpkytiplmnlirtvkqhhtnsvgaivvhcsaGvGrtGtfitldavldqaeaenaidvynfitgvrqnrikmvqvaeqyqfiy
|
|||||||||
| subfamily_PTPN23_pd | Subfamily PTPN23 | 856-1042 | 2.3e-18 | 61.0 | In-house | 88-273 (288) | alignment | ||
Range on Protein: 856-1042
Range on HMM: 88-273/288.0
TDKPKRSTCEKHWALIEQHNVAICVQLCGFVEGEDKKCASYYSDKVGGVLRFRNyslktidIKTDLAEFTDKKDFTLYTVEITNYRKnkgEQKKTVDILL
| |..|| | .. . . . | | | ...|...|. . | .| . .. | . .. . . ...... .. ...|.| |
tqaPlqstlnDFWlmvyeqkssviVmllskeelgkpkvdrYwPedkgetvkfgd.......lsvtlksvretethvervlkletlda...davksvshlq
YSAWPEHGAPQEAYPALEILKFCET--------YKKNVLVHCSEGVGRTGTLvAIKYGI--DLCLKKKVTQIIDIILPVRQCRHGAVQDDTQVTYIL
. .|||.|.|. |..|. |. |. ..|||| ||||||.. |. |.. .| .. ...||... .|. |. ||. .|. .
ltsWpelGvPasPetllqfldevesayeavqrksktPlvvhCsaGvgRtgvf.alvyaavrelekgnglldiiqvvsrlreqRrfmvqekeqlkfsy
|
|||||||||
| subfamily_Cele-PTP-13_pd | Subfamily Cele-PTP-13 | 856-1025 | 6.4e-17 | 56.1 | In-house | 86-244 (281) | alignment | ||
Range on Protein: 856-1025
Range on HMM: 86-244/281.0
TDKPKRSTCEKHWALIEQHNVAICVQLCGFVEGEDKKCASYYSDKVGGVLRFRNYSLKTIDIKTdlaeftdKKDftLYTVEItNYrKNKGEQKkTVDILL
|. ||. | | .| | | . | || |.| . .||| |. . .|.| ..|.. | .| | | . | .|| . . |
tqgpkketradfwrmiwqenttaivmlcqfletnrekcaeyfprnahcclqfdklsvsyedstv.......nks..lvttrl.nl.syegetr.lithwl
YSAWPEHGAPQEAYPALEILKFCETYKKNVLVHCSEGVGRTGTLVAIKYGIDLCLK-KKVTQIIDIILPVR
. ||. |. . |.||. . ..||| ||||.|||.|.. .. . .| .|. .|
wkewpdwqvpessevmlkilrkirarstppvihcsagvgrsgtlmaveialqsihshftlpdikqivshlr
|
|||||||||
| subfamily_CG7180_pd | Subfamily CG7180 | 856-1046 | 2.4e-16 | 54.2 | In-house | 90-287 (296) | alignment | ||
Range on Protein: 856-1046
Range on HMM: 90-287/296.0
TDKPKRSTCEKHWALIEQHNVAICVQLCGFVEGEDkKCASYYSDKVggVLRFRNYSLKTIDIKTdLAEFTDkKDFTLYTV--EITNYRKNKGEQKKTVDI
|. ||..| ...| |. .... | |. . . .. ||. | .... .... |. .|... . | |. .|. .|. ....|
teapkketvdefWrlvydeeisavvvLtktfdfak.mypsywpnks..keqygeifveiveekq.yanlki.rtfkltkkivalteqekqvkaetRivkl
LLYSAWPE-HGAPQEAYPALEILKFCETYKKNV---------LVHCSEGVGRTGTLVAIKYGIDLCLKKKVTQIIDIILPVRQCRHGAVQDDTQVTYILL
. . |. . | . .|... ......| .|..|.|..|.| .|| ..| |.. .. . . .|. | . |. .. ||
fqlteWeledkvPlstnalielrrrvrlwrekvdedpeegPvvvvssdGasRsGvylaidanlelvekeeevdvFeavktlrrsRpqLvenveeYkyiYd
CVT
.
vll
|
|||||||||
| subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 856-1053 | 3.4e-14 | 47.7 | In-house | 96-288 (325) | alignment | ||
Range on Protein: 856-1053
Range on HMM: 96-288/325.0
TDKPKRSTCEKHWALIEQHNVAICVqLCGFVEGEDKKCASYYSDKVGGVLRFRNYSLKTIDIKtdlaEFtdkKDFTLYTVEITNYrkNKGEqKKTVDILL
. |. .| . | |. . . .. | . .......|| |. ...| .| .| . |. |. |. ... . .||| ..| .
aqaPltatindlWrlvldWrcsvvv.vlneldlgkdrcavywpkemgksktfGglevklrtie....ei...sdyvhrvldvkqv..kkGe.trsvkqfq
YSAWPEHGAPQEAYPALEILKFCETY----K------KNVLVHCSEGVGRTGTLVAIKYGIDLCLKKKVTQIIDIILPVRQCRHGAVQDDTQvtYILlcV
. .|.. | .. . ||. .. . .|||||.||||||..... .. ... | . . .|. | |. | ||| .
lqswddmGvqkrpatlisilqlvkavservtantkastpilvhcsaGvGrtGvfislysalakvieesrvdifgfvkklrkdrpsmvetvdq..yil..i
TKGLMEKM
..|.| .
yealveay
|
|||||||||
| subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 856-1041 | 5e-12 | 40.4 | In-house | 77-251 (267) | alignment | ||
Range on Protein: 856-1041
Range on HMM: 77-251/267.0
TDKPKRSTCEKHWALIEQHNVAICVQLCGFVEGEdkkCASYYSDKVGGVLRFRNYslkTIDikTDLAefTDKKDFTLYTVEItnyrKNKGEQKKTVDILL
| .| . | ... .| ...|.. | | ... .. |.| .... |.. | ...|. . |.|. | | | . | .
tqdplkntitdfltvihdqkvpvivlltkvftdn...irlfwPPkmgqakkyqdl...tve..hsle..keendyqiitlel....kfknesahnvtlyy
YSAWPEHGAPQE-AYPALEILK--FCETYKKNVLVHCSEGVGRTGTLVAIKYGIDLCLKKKVTQIIDIILPVRQCRHGAVQDDTQVTYI
| | . | . || | . ..|.||.||||.||.. |. .. . |..| | .. .|. | | |. . ||
ykkwnintnnkpylkplfgilaknqlengnrPlvvacsdGvGrsGtflvidsqleraktegvsdifdflrkirsqriglvdtkeryiyi
|
|||||||||
| 0051429 | (Phosphotyrosine protein) phosphatases II | 857-1056 | 1.1e-24 | 83.0 | In-house | 28-232 (272) | alignment | ||
Range on Protein: 857-1056
Range on HMM: 28-232/272.0
DKPKRSTCEKHWALiEQHNVAICVQLCGFVEGEDKKCASYYsdkvggvLRFRNYSLKTIDIKTDLAEFTD----------KKDFTLYTVEITNYRKNKGE
. | . |.. |.| ..... | |.. .| . || | .| . | ..| . .. . . |..|.. ..|.. ...
ggplpltaadfwrl.kelgiktivdLrseeErgrlkcdryw.......pgirylhlpilddsaptilygalrvtllseellldyilrellltlllsagea
qkKTVDILLYSAWPEHGAPQEAypALEILKFCETyKKNVLVHCSEGVGRTGTLVAIKYGIDLCLKKKVTQ--------IIDIILPVRQCRHGAVQDDTQV
.| .|.| .|| ||.|||| ||.|... . ...|||||| |..||||.||. . . . . . . ... .|..|.||||...|.
..revmhlhytdwpdhgvpqea..llellellld.ggpvlvHCsaGkdRTGtvvallllllgvsletivddYlltnlyleeaveelraqrpgavqteeqy
TYILLCVTKGLMEKMPVP
... .. . |.. . |.
lflyeallellrsllsvr
|
|||||||||
| subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 858-1040 | 7e-10 | 33.1 | In-house | 87-268 (287) | alignment | ||
Range on Protein: 858-1040
Range on HMM: 87-268/287.0
KPKRSTCEKHWALIEQHNVAICVQLCGFVEGEDKKCASYYSDKvGGVLRFRNYSLKTIDIKTDlaeftdKKDFTLYTVEITNYrknKGEQKKTVDILLYS
| .| . | .. ....| . . || .|| |. .. .| ||. .| . . ... .. . . .... . | | .
gPiaatvrdfwravletrsasvitmtreveearlkcykywPer.evPmrvGGysvvlldydik......ePeygvralrlidl...etrearvvkqldll
AWPEHGAPQE----AYPALEILKFCETYKK-----NVLVHCSEGVGRTGTLVAIKYGIDLCLKKKVTQIIDIILPVRQCRHGAVQDDTQVTY
.||..... . .|.. .. | .. ..||.. |.||.|.|.|. .. .. . ... .|. | . || |. .
swPdkvlaPtavglirfvldvkqhielardasevGPlvvhddvGiGrsGillatlvlvsrledlGrvdvaavvirlreyraalvqavvqlrl
|
|||||||||
| subfamily_Cele-PTP-14_pd | Subfamily Cele-PTP-14 | 858-1042 | 1.4e-08 | 28.7 | In-house | 101-283 (310) | alignment | ||
Range on Protein: 858-1042
Range on HMM: 101-283/310.0
KPKRSTCEKHWALIEQHNVAICVQLCGFVEGEDKKCASYYSDkVGGVLRFRNYSLKTIDIKTDLAEFTDK-KDFTLYTVEITNYRKNKgeQKKTVDILLY
| . | | .| | . || .| || .|. .| . . . .. | . | | . . | .. |... .
gplqhtiidfwrmifqeraesilllckvgeegrpkcvgywps.lgvtetygcirvtnlsesseefeicnlavtfvpdnvpvdeqpanl..kelrvslikw
SAWPEHGAPQEAYPALEILKFCETYKKNVLVHCSEGVGRTGTLVAIKYGIDLCLKKKVTQIIDIILPVRQCRHGAVQDDTQVTYIL
||. | |.| .. ... . ..|||| |..|....||.|. || . . .. ... ... | .| . | ..|
pnwpdrgvpdekchtvpqrllaqvrhgpcvvhcsagkdrlyvvvalklkidkldrglkvdaeevktellksraiciqtelqyliid
|
|||||||||
| subfamily_Nvec-PTP-3_pd | Subfamily Nvec-PTP-3 | 858-1033 | 7e-06 | 20.3 | In-house | 11-187 (198) | alignment | ||
Range on Protein: 858-1033
Range on HMM: 11-187/198.0
KPKRSTCEKHWALIEQHNVAICVQLCGFVEGEDKKCASYYSDKVGGVLRFRNYSLKTidiKTdlaeFTDKKDFTLYTVEITNYRKNKGeQKKTVDILLYS
.| | | | .. . | . . . |.. |. .. . |. | || | | |.|. .. .|| . . ..
hplretladfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvtt...kt....ittkpdytitaliltnnttapp.streishyqft
AWPEHGAPQEAYP------ALEILKFCETYK-KNVLVHCSEGVGRTGTLVAIKYGIDLCL--KKKVTQIIDIILPVRQCRHGAVQ
.| |. .|. | . |. | | | |.||||.| | || .||. |. | | ..... .||.| | .
swkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiis
|
|||||||||
| subfamily_Anemone-PTP-3_pd | Subfamily Anemone-PTP-3 | 858-1033 | 7.3e-06 | 20.3 | In-house | 12-188 (199) | alignment | ||
Range on Protein: 858-1033
Range on HMM: 12-188/199.0
KPKRSTCEKHWALIEQHNVAICVQLCGFVEGEDKKCASYYSDKVGGVLRFRNYSLKTidiKTdlaeFTDKKDFTLYTVEITNYRKNKGeQKKTVDILLYS
.| | | | .. . | . . . |.. |. .. . |. | || | | |.|. .. .|| . . ..
hplretmadfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvtt...kt....ittkpdytitaliltnnttapp.streishyqft
AWPEHGAPQEAYP------ALEILKFCETYK-KNVLVHCSEGVGRTGTLVAIKYGIDLCL--KKKVTQIIDIILPVRQCRHGAVQ
.| |. .|. | . |. | | | |.||||.| | || .||. |. | | ..... .||.| | .
swkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiis
|
|||||||||
| subfamily_Cele-PTP-4_pd | Subfamily Cele-PTP-4 | 864-1046 | 5.1e-06 | 20.1 | In-house | 106-282 (302) | alignment | ||
Range on Protein: 864-1046
Range on HMM: 106-282/302.0
CEKHWALIEQHNVAICVQLCGFVEGEDkKCASYYSDKVGgvlRFRNYSLKTIDIKTdlAEFTDKKDfTLYTVEITNyrkNKGEQKKTVDILLYSAWPEHG
|. | .. |.... | | | | . .. | | . .| . .. | .... | |..|. . . . . . . |...
veeFWrmvfqekivsvvilvgeeelkk.tlselfpkksg...dykeygkmfvNnrk..Vekaeeek.tryviEvlP...egcsnsvlanvyvltnWkqkk
APQEAYP----ALEILKFCETYKKNVLVHCSEGVGRTGTLVAIKYGIDLCLKKKVTQIIDIILPVRQCRHGAVQDDTQVTYILLCVT
|.. | .. . . ..|... .|.|| |.... .. |.| .| .|. .|. | ||. .| . . ...
vpvkyaeliktaakvfakkikadentvivSknGaGRagafltlavaveklqkgkepnikeivksiRsqRpravdslkQyvslyiall
|
|||||||||
| 0044763 | (Phosphotyrosine protein) phosphatases II | 865-1047 | 3.6e-19 | 64.6 | In-house | 38-169 (178) | alignment | ||
Range on Protein: 865-1047
Range on HMM: 38-169/178.0
EKHWALIEQHNVAICVQLCGFVEGEDKKCASYYSDKVGgvlrfrnyslktidiktdlaeftdkkdftlytveitnyrknkgeqkktvDILLYSAWPEHGA
.....|. .... | |.. .|. || |. .. | |. .| ||.
addlellkelgithivnlteelelgflkcdpywpeeag.................................................iqylhipipDhgv
PQEAYPALEILKFCE----TYKKNVLVHCSEGVGRTGTLVaikyGIDLCLKKKVtQIIDIILPVRQCRHgAVQDDTQVTYILLCVTK
|. ||...|.| . ...|||||| ||||.|||| ..|..| .. . ..| ||..| .|. . |. ..... .
pdllehflefvefieealdekggpvlVHCsaGvgRsgtlv....aaylmkklgl.sleeaielvrerRp.ivpnpgqlrqLyefelr
|
|||||||||
| DSPc | Dual specificity phosphatase, catalytic domain | 922-1001 | 1.5e-07 | 26.4 | Pfam-A | 11-92 (133) | alignment | ||
Range on Protein: 922-1001
Range on HMM: 11-92/133.0
AEFTDKKDFTLYTvEIT-NYRK---NKGEQKKTVDILlYSAWPEHGAPQEAYPALEILKFCETYKKNVLVHCSEGVGRTGTLVA
....|...|| ..| . .. | .... ..| | .| | |... .|. .|.||||| |. |..||..
lalleklgitlvi.nvtkevpnnnaikkseieylrip.vedetetkiskeleeavefiekaeqkgkkvlVHCqaGisRSatlii
|
|||||||||
| DSPc | Dual specificity phosphatase, catalytic domain | 922-1001 | 1.5e-07 | 26.4 | In-house | 11-92 (133) | alignment | ||
Range on Protein: 922-1001
Range on HMM: 11-92/133.0
AEFTDKKDFTLYTvEIT-NYRK---NKGEQKKTVDILlYSAWPEHGAPQEAYPALEILKFCETYKKNVLVHCSEGVGRTGTLVA
....|...|| ..| . .. | .... ..| | .| | |... .|. .|.||||| |. |..||..
lalleklgitlvi.nvtkevpnnnaikkseieylrip.vedetetkiskeleeavefiekaeqkgkkvlVHCqaGisRSatlii
|
|||||||||
| 0048076 | (Phosphotyrosine protein) phosphatases II | 934-1045 | 3.5e-17 | 57.9 | In-house | 35-139 (145) | alignment | ||
Range on Protein: 934-1045
Range on HMM: 35-139/145.0
TVeitnyRKNKGEQKKTVDILLYSAWPEHGAPQEAYPALEILKFCETY---KKNVLVHCSEGVGRTGTLVAIkygiDLCLKKKVTqIIDIILPVRQCRHG
.. .. .... .|| || ||.|. . ||.|.|.|.. ...|||||| ||||||||||. .|.|...|. . ... ||..|.|
nl.....tselellerlgiqylylpwpDhgvpdllellleflefieealkeggpvlVHCsaGvgRtgtlvaa....ylmlllgvs.leealelvrsqrpg
AVQDDTQVTYILLCV
||. . |. ......
avpnpgqlrflyefe
|
|||||||||
| subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 945-1050 | 7.4e-09 | 29.4 | In-house | 85-195 (440) | alignment | ||
Range on Protein: 945-1050
Range on HMM: 85-195/440.0
GEQKKTVDILLYSAWPEHGAPQEAYPALEILKFCET-YK----KNVLVHCSEGVGRTGTLVAIKYGIDLCLKKKVTQIIDIILPVRQCRHGAVQDDTQVT
| . .|. | .||..| |. | | |.... . . .||||| |.|||| ..|. . . . .|. .| .|. | || | .
giesrtlkqyhyqgwpdkgvpkfagpvlkmiqdvnesqekagngpllvhcsagagrtgviiavdsilreakrsdqidifsfinsmrnnrpqmvqtpeqya
YILLCVTKGLM
.. .| .||.
fvheavlegll
|
|||||||||
| PTPc_motif_SM00404 | 948-1002 | 2.9e-07 | 25.5 | In-house | 47-100 (140) | alignment | |||
Range on Protein: 948-1002
Range on HMM: 47-100/140.0
KKTVDILlYSAWPEHGAPQEAYPALEILKFCETYKKNVLVHCSEGVGRTGTLVAI
.. . | . . .. .|.... .|. ...||||| || |..||..
fqilqip.lddnekdklskyldkvldfienaekkggkvlVHCqaGvSRSatliia
|
|||||||||
| PTPc_DSPc_SM00012 | 951-1045 | 8.4e-21 | 69.5 | In-house | 2-103 (105) | alignment | |||
Range on Protein: 951-1045
Range on HMM: 2-103/105.0
VDILLYSAWPEHGAPQEAYPALEILKFCETYKK------NVLVHCSEGVGRTGTLVAIKYGIDLCLKK-KVTQIIDIILPVRQCRHGAVQDDTQVTYILL
| . |..||.||.|.|. . ||.|. ... |. .|.|||| |||||||.||. . .. . |. | .| .|. .|. |.|.|| ..|. ...
vkhyhytgwpdhgvPeesdsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgmvqteeqylflyr
CV
..
al
|
|||||||||
| 0048179 | (Phosphotyrosine protein) phosphatases II | 951-1043 | 7.6e-17 | 56.8 | In-house | 49-139 (144) | alignment | ||
Range on Protein: 951-1043
Range on HMM: 49-139/144.0
VDILLYSAWPEHGAPQEAYPALEILKFCETY---KKNVLVHCSEGVGRTGTLVAIkygiDLCLKKKvTQIIDIILPVRQCRHGAVQDDTQVTYILL
. .|. || ||.|. . ||.|.|.|.. ...|||||| ||||||||||. .|..|.. . ... ||..| |||. . |. ..|.
giqylhlpwpDhgvpdllellleflefieealeeggpvlVHCsaGvgRtgtlvaa....ylmkklg.lsleealalvrsrrpgavpnpgqlrfLle
|
|||||||||
| 0038934 | (Phosphotyrosine protein) phosphatases II | 971-1041 | 1.6e-07 | 26.7 | In-house | 99-169 (194) | alignment | ||
Range on Protein: 971-1041
Range on HMM: 99-169/194.0
ALEILKFCETY-----KKNVLVHCSEGVGRTGTLVAIKYGIDLCLkkkvtQIIDIILPVRQCRHGAVQDDTQVTYI
|..|...... .. |.||| |.|||||||| |.. . | .|..| ||.. .. ..
llrfldlvdeflnedpggvvaVHCkaGlgRtGtlvaaYLiyrlgm.....saeeAialfrekRpgaipnqdyleal
|
|||||||||
| subfamily_CDC14_pd | Subfamily CDC14 | 973-1036 | 3.6e-06 | 21.0 | In-house | 254-312 (328) | alignment | ||
Range on Protein: 973-1036
Range on HMM: 254-312/328.0
EILKFCETYKKNVLVHCSEGVGRTGTLVAIkYgidlCLKKKVTQIIDIILPVRQCRHGAVQDDT
. |. .|. . .. ||| |.||||||.| | .|. . ..| .| || | |
kfleiaekaeGaiavhCkaGLGrtGtLiac.y....lmkhyrftaaeaiawlricrPGsvigpq
|
|||||||||
| subfamily_DSP23_pd | Subfamily DSP23 | 973-1037 | 7.9e-06 | 20.6 | In-house | 75-134 (148) | alignment | ||
Range on Protein: 973-1037
Range on HMM: 75-134/148.0
EILKFCETYKKNVLVHCSEGVGRTGTLVAIKYgidlcLKKKVTQIIDIILPVRQCRHGAVQDDTQ
.... | .. | ||| | |||||..| . .|.. . | ||. | |.|. |
rvveeaeekneavsvhcllgrgrtgtmlacyl.....vkerklaaaeaiaevrrlrpgsvetveq
|
|||||||||
| subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 975-1047 | 5.9e-07 | 23.6 | In-house | 221-293 (297) | alignment | ||
Range on Protein: 975-1047
Range on HMM: 221-293/297.0
LKFCETYKKNVLVHCSEGVGRTGTLVAIKYGIDLCLKKKVTQIIDIILPVRQCRHGAVQDDTQVTYILLCVTK
|. . .||||| ||||.| .| . .. ||.. .. |. .|. | || | ... | |
lraemprnayllvhcsaGvGrsGvvvlsdvilaklrkkripdvaailsilreqrarlvqtleqfellydavlk
|
|||||||||
| PTEN_1 | 982-1001 | 5.5e-06 | 21.3 | In-house | 130-149 (196) | alignment | |||
Range on Protein: 982-1001
Range on HMM: 130-149/196.0
KKNVLVHCSEGVGRTGTLVA
...||||| |.||.||.||
gnvVlVHCkaGlgRsGtvva
|
|||||||||
| subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 983-1004 | 3.8e-06 | 20.9 | In-house | 263-284 (350) | alignment | ||
Range on Protein: 983-1004
Range on HMM: 263-284/350.0
KNVLVHCSEGVGRTGTLVAIKY
. .||||| |||||||||.. .
spilvhCsaGvGrtGtlvtlDs
|
|||||||||
| subfamily_CG42327_pd | Subfamily CG42327 | 984-1042 | 3.9e-08 | 27.3 | In-house | 249-308 (319) | alignment | ||
Range on Protein: 984-1042
Range on HMM: 249-308/319.0
NVLVHCSEGVGRTGTLVAIKYGID-LCLKKKVTQIIDIILPVRQCRHGAVQDDTQVTYIL
. ||||.||||||...| | | |. | ... ||. | ||.. | .|
PlvvhcsdGvGrtGlviasdiairsleeskrsvdiPqlvssvrrdrasavltkeqyefiy
|
|||||||||
| subfamily_Sponge-PTP-7_pd | Subfamily Sponge-PTP-7 | 986-1041 | 1.6e-06 | 22.4 | In-house | 2-57 (69) | alignment | ||
Range on Protein: 986-1041
Range on HMM: 2-57/69.0
LVHCSEGVGRTGTLVAIKYGIDLCLKKKVTQIIDIILPVRQCRHGAVQDDTQVTYI
.|||| | |||||..|| . .|. | . . .|.|| | .. . .|
vvhcssgtgrtgtfiaimvemarikseklvdifnnvqymrkcrpmmvmneieyifi
|
|||||||||
| subfamily_Sponge-PTP7_pd | Subfamily Sponge-PTP7 | 987-1041 | 2.9e-06 | 21.5 | In-house | 2-56 (69) | alignment | ||
Range on Protein: 987-1041
Range on HMM: 2-56/69.0
VHCSEGVGRTGTLVAIKYGIDLCLKKKVTQIIDIILPVRQCRHGAVQDDTQVTYI
|||| | |||||..|| . .|. .| . . .|.|| | .. . .|
vhcssGtGrtGtfiaimvemarikseklvdifnnvqymrkcrpmmvmneneymfi
|
|||||||||