Gene lip-1 in Caenorhabditis elegans

Synonym: CELE_C05B10.1, lip-1

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family DSP
Subfamily DSP6
Protein sequence
ID Type Fasta BLAST phosphatome Note
CeleP123_AA protein Get Run
CeleP123_AA_182-329 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
0037934 (Phosphotyrosine protein) phosphatases II 158-324 3.9e-27 90.8 In-house 16-240 (243) alignment 
Range on Protein: 158-324
Range on HMM: 16-240/243.0
ASSGPLLNLNQLRLEGedqGGKQRAEFpVKLTNFLYLGNA--------ETAKNRDVLKKYSISHVINVTSNL----------------------------
 |. .... .. .|||   ..   | . .. |. |.....         .|.. . |... |......|.                              
ysdilpydhsrvkleg...sdyinanl.iyvtprliatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqywpgevtygdftvtllsee

--------------PN-TFEEDPNMRYLRISADD----NASHNLTKFFPEAISFIDD-----ARRNDSACLVHCLAGISRSVTICLAYLMKTE-MCTLDS
              .. . ..  ...|....  |    .   .| .|. |...||..     |. ... .|||| ||..|. |...||||..   ..|..
hlddytvrtlllenldlddltrlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgRtGtliaaylmllllgvdlee

AYEWVQKRNAS-IAPNFHFMGQLTDYEKM
|.......    . ...... .| .....
avkllreqRpgkavqtpsqyrflyealle
subfamily_DSP6_pd Subfamily DSP6 174-328 2.7e-78 255.0 In-house 3-157 (158) alignment 
Range on Protein: 174-328
Range on HMM: 3-157/158.0
EDQGGKQRAEFPVKLTNFLYLGNAETAKNRDVLKKYSISHVINVTSNLPNTFEEDPNMRYLRISADDNASHNLTKFFPEAISFIDDARRNDSACLVHCLA
||.. |..|||||.....||||.|..|.|..||||..|..|.||||||||.|||.....||.|...|..|.||.|||||||.|||.||...|..||||||
edklkkaeaefpveilpllylGsakdasnlevlkklkikyvlnvtsnlpnkfeesgelkylqipiedhlsqnlakffPeaiefidearskkskvlvhCla

GISRSVTICLAYLMKTEMCTLDSAYEWVQKRNASIAPNFHFMGQLTDYEKMLGLN
|||||||..||||||.....|..||..|.||...|.|||.|||||.|.|..|.|.
GisrsvtvtlaylmkklalslndaydlvkkrksnisPnfnfmgqlldferslrls
0049772 (Phosphotyrosine protein) phosphatases II 178-327 2.3e-30 101.8 In-house 117-275 (314) alignment 
Range on Protein: 178-327
Range on HMM: 117-275/314.0
GKQRAEFPVK---------------------LTNFLYLGNAETAKNRDVLKkysishvinvTSNLPNTFEEDPNMRYLRISADDnASHNLTKFFPEAISF
|...   .|.                     |...  .||  ||.. . ||          .   .. . |.....||||  .|  | .|...|.|.. |
gdlnvrdivmsrdevladelsrLdaAlgKtpllildgngneptaadlellk..........eelydpelferlgikylripvpD.gsaplledfdeflef

IDDArRNDSACLVHCLAGISRSVT-ICLAYLMKTEMCTLDSAYEWVQKRNAsIAPNFHFMGQLTDYEKMLGL
|..| ..... |||| ||..|. | ...|||||   ..|. |.|.|....  | ||..|. || .||..|  
ieea.dkggpvlvHCkaGkgRtgtfvvaaylmkllgvsleealedvrlkRp.inpnpgfieqleqyefilea
subfamily_DSP10_pd Subfamily DSP10 183-326 9.3e-51 165.8 In-house 12-154 (159) alignment 
Range on Protein: 183-326
Range on HMM: 12-154/159.0
EFPVKLTNFLYLGNAETAKNRDVLKKYSISHVINVTSNLPNTFEEdPNMRYLRISADDNASHNLTKFFPEAISFIDDARRNDSACLVHCLAGISRSVTIC
   ...  ||.||... |.. |.|....|..|.|||...||.|||  ...| || . |. ..|| . | ||. ||..||...|  |||| ||||||.|. 
apasqvlpfLflGsekdaadldaldrlnitavlnvttsvPnefee.ealkYkripvsDtskqnlkqyfeealefieearkkgsrvLvhCqaGisrsatvv

LAYLMKTEMCTLDSAYEWVQKRNASIAPNFHFMGQLTDYEKMLG
.|||||    .|  ||..|... . |.||. ||||| ..|| | 
iaYlmkhlnlslndaykfvkekrpiisPnLnfmGqLlefekeln
subfamily_DSP1_pd Subfamily DSP1 183-328 5e-47 154.0 In-house 16-159 (163) alignment 
Range on Protein: 183-328
Range on HMM: 16-159/163.0
EfPVK-LTNFLYLGNAETAKNRDVLKKYSISHVINVTSNLPNTFEEdpNMRYLRISADDNASHNLTKFFPEAISFIDDARRNDSACLVHCLAGISRSVTI
. ||. ...||||| ...| |...||.  |....||...|.|.||.   ..| ..  .|. . .... | |.| |||......   |.|| |||||| |.
d.PvekildfLylGsetvasnleiLkslgitailnvskeldnvfed..lfeYkklkleDspkadislvfeeviefidevkkknGkvlihCqaGisRsstl

CLAYLMKTEMCTLDSAYEWVQKRNASIAPNFHFMGQLTDYEKMLGLN
||||||||. ..|. |...|..| . | ||. |..|| .||| |.|.
claylmktkrvsleeafdfvkqrRsiisPnagFvlqLlnyekkllle
subfamily_Slingshot_pd Subfamily Slingshot 183-330 8.9e-36 116.8 In-house 17-162 (169) alignment 
Range on Protein: 183-330
Range on HMM: 17-162/169.0
EFPVKLTNFLYLGNAETAKNRDVLKKYSISHVINVTSNLPNTFEEdpNMRYLRISADDNASHNLTKFFPEAISFIDDARRNDSACLVHCLAGISRSVTIC
. . |. ...|||    | | . ||. ......||| .. | |.|  ...||.|.  |. ...| |.. |. .||. |....| .||||  |.||| .. 
dsaskifdhvylGsewnasnleelkengveyilnvtkeidnffpe..kfeylnirvydeeetdllkywnetykfiekakkkgskvlvhckmGvsrsastv

LAYLMKTEMCTLDSAYEWVQKRNASIAPNFHFMGQLTDYEKMLGLNSN
.|| ||.  ..|..|.|.|..|   | ||  |. ||. || .|  . .
iayamkeyglsleealeyvkerrsvikPnkgflkqleeyeGileaskq
0045098 (Phosphotyrosine protein) phosphatases II 183-326 3.6e-28 94.2 In-house 20-272 (278) alignment 
Range on Protein: 183-326
Range on HMM: 20-272/278.0
EFPVKLTNFLYLGNAE-----------------------------------------TAKNRDVLKKYSISHVINVTSNLPN------------------
 .| . |..|||||..                                         .|.. . |... |......|. ...                  
gipseitpalylgnldknRykdilpydhsrVkdYINAsyidgypkkfIatqgPlpstvadfwrmlwelgitvivmltelvelgrekcaqywpeggsltyg

-----------------------------TFEEDPNMRYLRI-SADDNASHNLT--KFFPEAISFIDDARR--------------NDSACLVHCLAGISR
                             .  |  ....| . . .|. ...|.  |.| |.. ||..|..              ..  .|||| ||..|
dftvtllseevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllsslllldsggpvlVHCsaGvgR

SVTICLAYLMKTE---MCTLDSAYEWVQKRNAS-IAPNFHFMGQLTDYEKMLG
. |...||||..     ..|..|.......    . .|.... .| ... .| 
tGtlvaaylmlelleggvdlleavkelrsqRpglavqnleqyrflyefllell
0048179 (Phosphotyrosine protein) phosphatases II 184-325 1.4e-36 120.7 In-house 3-144 (144) alignment 
Range on Protein: 184-325
Range on HMM: 3-144/144.0
FPVKLTNFLYLGNAETAKNRDVLKKYSISHVINVTSNLPNTFEEDPNMRYLRISADDNASHNLTKFFPEAISFIDDARRNDSACLVHCLAGISRSVTICL
.|.. .. ||||.  ||.. . |||. |..|||.|.. ...|.|.....||... .|.   .|.....|.. ||..|....  .|||| ||..|. |...
npseilpglylgslptaldlellkklgittvinlteeyepefleregiqylhlpwpDhgvpdllellleflefieealeeggpvlVHCsaGvgRtgtlva

AYLMKTEMCTLDSAYEWVQKRNASIAPNFHFMGQLTDYEKML
|||||.. ..|..|...|..|.  . ||.... .| .|||.|
aylmkklglsleealalvrsrrpgavpnpgqlrfLleyekll
0048076 (Phosphotyrosine protein) phosphatases II 184-325 1.6e-34 114.0 In-house 3-142 (145) alignment 
Range on Protein: 184-325
Range on HMM: 3-142/145.0
FPVKLTNFLYLGNAETAKNRDVLKKYSISHVINVTSNLPNTFeeDPNMRYLRISADDNASHNLTKFFPEAISFIDDARRNDSACLVHCLAGISRSVTICL
.| . .. ||||.  ||.... ||.. | .|.|.||.|.. .  . ...||... .|.   .|.....|.. ||..|....  .|||| ||..|. |...
wpseilpglylgslptaldlellkdlgittvlnltselelle..rlgiqylylpwpDhgvpdllellleflefieealkeggpvlVHCsaGvgRtgtlva

AYLMKTEMCTLDSAYEWVQKRNASIAPNFHFMGQLTDYEKML
||||... ..|..|.|.|...   . ||.... .| ..|..|
aylmlllgvsleealelvrsqrpgavpnpgqlrflyefelel
subfamily_Choan-DSP_MKP-1_pd Subfamily Choan-DSP_MKP-1 184-323 9.2e-32 103.6 In-house 6-145 (148) alignment 
Range on Protein: 184-323
Range on HMM: 6-145/148.0
FPVKLT-NFLYLGNAETAKNRDVLKKYSISHVINVTSNLPNTFEEDpNMRYLRISADDNASHNLTKFFPEAISFIDDARRNDSACLVHCLAGISRSVTIC
|| ..   ||.||. . | . ..||.  .....| | . .|....   ..|| .. ||.  ..| ..|...|.|.. |. .   .|||.  |.|||  . 
fpseikdafLFlGskksaadlealkalgvtrivnatkerdnaldqr.gieYlhvaldDkpkedlsaiFediiafvrkakdeGrrvLvhlqmGvsrssala

LAYLMKTEMCTLDSAYEWVQKRNASIAPNFHFMGQLTDYEK
|..|....  .|  |.. |. .   . ||  |. ||...|.
llwlidfkrvslkealalvkskrryvdpnlgfLkqLaeleq
0041856 (Phosphotyrosine protein) phosphatases II 184-326 6.1e-31 102.8 In-house 18-173 (182) alignment 
Range on Protein: 184-326
Range on HMM: 18-173/182.0
FPVKLTNFLYLGNAET--------------AKNRDVLKKYSISHVINVTsnLPN---TFEEDPNMRYLRISADDNASHNltkfFPEAISFIDDARRNDSA
.. . .. ||||.  .              |.. . ||.. |....|.|   ..   ...|. ...||... .|.   .    ..|...||....... .
dldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlt..eelywpellerlgiqylylpwpDhgvpd....ldelldfieevleeggp

CLVHCLAGISRSVTICLAYLMKTEMCTLDSAYEWVQKRNA--SIAPNFHFMGQLTDYEKMLG
.|||| ||..|. |...|||||.  ..|..|...|..|     | ||..|. ||  .|..|.
vlVHCsaGvgRtgtlvaaylmkklgvsleeavklvrsrRpgmvitpnqyfflqlallellll
subfamily_LRR-DSP_pd Subfamily LRR-DSP 184-325 3.9e-29 95.6 In-house 119-258 (263) alignment 
Range on Protein: 184-325
Range on HMM: 119-258/263.0
FPVKLTNFLYLGNAETAKNRDVLKKYSISHVINVTSNLPNTFEEdpNMRYLRI-SADDNASHNLTKFFPEAISFIDDARRnDSACLVHCLAGISRSVTIC
 | .. . |.||  ..|.|. .||. ...|..   ...   | .   ..|| |  ..|    .. ..| |  .||.. |.     |||| ||.||| |. 
vPdeiidklflGgldsannksilkdlgvthillavadfePlfPk..lfkylsiddiedvdeadisqhfeetnafieeGrk.kGGvlvhcraGvsrsstlv

LAYLMKTEMCTLDSAYEWVQKRNASIAPNFHFMGQLTDYEKML
..|||| .  ..  |.. |.|. . | ||  |. ||  ||| |
isylmkkqrlkfkealdlvikkrpriqPnpGfkdqlkkyekkl
subfamily_STYXL1_pd Subfamily STYXL1 184-325 2.5e-27 89.0 In-house 10-153 (157) alignment 
Range on Protein: 184-325
Range on HMM: 10-153/157.0
FPVK-LTNFLYLGNAETAKNRDVLKKYSISHVINVTSNLPNTFEEDPN-MRYLRISADDNASHNLTKFFPEAISFIDDARRNDSACLVHCLAGISRSVTI
.||  | ..||||| . |.|. . |   .  ..||...  . .. ...  . |.|. .|.   .| ... ||..||.. ...... ||    |||||...
yPvevlPgklylGnykqaqnpaikkdlkvkahvnvsmdadkliagvadvakllhiavedeneadllerlkeavqfiekhkkegevvlvfsnkGisrsaav

CLAYLMKTEMCTLDSAYEWVQKRNASIAPNFHFMGQLTDYEKML
 .||||  .  || .||. ..|    . ||  |. ||...||.|
iiaylmyskkitlkkaykylkkCkenvkPnrafveqlseWekql
subfamily_DSP8_pd Subfamily DSP8 185-326 4.1e-42 137.4 In-house 15-155 (159) alignment 
Range on Protein: 185-326
Range on HMM: 15-155/159.0
PVKLTNFLYLGNAETAKNRDVLKKYSISHVINVTSNLPNTfEEDPNMRYLRISADDNASHNLTKFFPEAISFIDDARRNDSACLVHCLAGISRSVTICLA
| .....||||  . . ....|.|. ||.|.|.  . |.. || .. ..||.   |. . .|  .|.....||| |..... .|||.||||||| |. .|
ptrilknlylGsqkdvlseellsklgisyvlnasnscpkl.eelkeskflrvPvkDkydekllpwfdksvefidkaksengrvlvhvlaGisrsatvaia

YLMKTEMCTLDSAYEWVQKRNASIAPNFHFMGQLTDYEKMLG
|.|||   .||.||..|... ..| ||. |.||| .||| | 
yimktlemsldeayrfvkekrptispnlnflgqLleyekelk
0043147 (Phosphotyrosine protein) phosphatases II 185-328 1.7e-33 111.2 In-house 19-163 (172) alignment 
Range on Protein: 185-328
Range on HMM: 19-163/172.0
PVKLTNFLYLGNAETAKNRDVLKKYSISHVINVTSN-LPNTFEEDPNMRYLRISADDNASHnLTKFFPEAISFIDD--ARRNDSACLVHCLAGISRSVTI
| ..  ......  .|.... ||.. |.|..|.|.  .. ...|. ...||... .|.    |.....|...|||.  |.... ..|||| ||..|..|.
pdrfiatqgplrntladfwrmlkelgithivnltellydpellerlgiqylylpwpDhgvp.llellleflefidellalspggpvlVHCsaGvgRtgtl

CLAYLMKtEMCTLDSAYEWVQKRNASIAPNFHFMGQLTDYEKMLGLN
..||||. . ..|. |...|...   . .|.... .| ..||.| |.
vaaylml.lglsleeavalvrekRpgavqnpsqyrflyyfeklllll
PTPc_motif_SM00404 186-324 3.1e-43 142.0 In-house 3-140 (140) alignment 
Range on Protein: 186-324
Range on HMM: 3-140/140.0
VKLTNFLYLGNAETAKNRDVLKKYSISHVINVTSNLPNTfEEDPNMRYLRISADDNASHNLTKFFPEAISFIDDARRNDSACLVHCLAGISRSVTICLAY
 . .. ||||....|.|...|||..|.||||||.. ..| .|......|.|  ||| . .|.|.......||..|...  ..|||| ||.|||.|...||
srilphlylgskskaqnpallkklgithvinvteevslt.kensgfqilqiplddnekdklskyldkvldfienaekkggkvlVHCqaGvSRSatliiaY

LMKTEMCTLDSAYEWVQKRNASIAPNFHFMGQLTDYEKM
||... ..|..||| |..|  .| ||..|. || .|||.
lmryrqlslaeayefvkerRpiispnlnfvrqLieyekk
0044763 (Phosphotyrosine protein) phosphatases II 186-329 3.4e-38 126.4 In-house 24-174 (178) alignment 
Range on Protein: 186-329
Range on HMM: 24-174/178.0
VKLTNFLYLGNAETAKNRDVLKKYSISHVINVTSNLPNTFEEDPN-------MRYLRISADDNASHNLTKFFPEAISFIDDAR-RNDSACLVHCLAGISR
.. ...||||.. .|.... ||.. |.|..|.|..|.. |....        ..||.|  .|.   .|...|.|.. ||..|. ......|||| ||..|
seilpglylgslppaddlellkelgithivnlteelelgflkcdpywpeeagiqylhipipDhgvpdllehflefvefieealdekggpvlVHCsaGvgR

SVTICLAYLMKTEMCTLDSAYEWVQKRNAsIAPNFHFMGQLTDYEKMLGLNS
| |...|||||.  ..|..|.|.|..|   | ||.... || ..|..|  .|
sgtlvaaylmkklglsleeaielvrerRp.ivpnpgqlrqLyefelrllkes
subfamily_MKPLT_pd Subfamily MKPLT 186-325 2.1e-31 102.7 In-house 23-160 (164) alignment 
Range on Protein: 186-325
Range on HMM: 23-160/164.0
VKLTNFLYLGNAETAKNRDVLKKYSISHVINVTSNLPNTFEEdpNMRYLRISADDNASHNLTKFFPEAISFIDDARRNDSACLVHCLAGISRSVTICLAY
| | . ||||||. |.|. |||.  | |..||. .  . | .   . ||... .|.. ..|..|.  |  |. ||  .    ||||  | ||| .. .|.
vvledtlylGnakhatnekvlkdlkithivnvsqekkdafpk..sveYlqvkvedesdeqlssfleraakfladaidsGGrvlvhcvqGksrsssvtvaf

LMKTEMCTLDSAYEWVQKRNASIAPNFHFMGQLTDYEKML
|.| .  ||. |||....| . .|||  |. ||. .|...
LikskgwtlkeayeylkerrsivapnrGflkqlakfeeli
subfamily_MKPLV_pd Subfamily MKPLV 186-325 2.1e-31 102.7 In-house 23-160 (164) alignment 
Range on Protein: 186-325
Range on HMM: 23-160/164.0
VKLTNFLYLGNAETAKNRDVLKKYSISHVINVTSNLPNTFEEdpNMRYLRISADDNASHNLTKFFPEAISFIDDARRNDSACLVHCLAGISRSVTICLAY
| | . ||||||. |.|. |||.  | |..||. .  . | .   . ||... .|.. ..|..|.  |  |. ||  .    ||||  | ||| .. .|.
vvledtlylGnakhatnekvlkdlkithivnvsqekkdafpk..sveYlqvkvedesdeqlssfleraakfladaidsGGrvlvhcvqGksrsssvtvaf

LMKTEMCTLDSAYEWVQKRNASIAPNFHFMGQLTDYEKML
|.| .  ||. |||....| . .|||  |. ||. .|...
LikskgwtlkeayeylkerrsivapnrGflkqlakfeeli
0046846 (Phosphotyrosine protein) phosphatases II 186-325 4.4e-27 90.4 In-house 13-172 (176) alignment 
Range on Protein: 186-325
Range on HMM: 13-172/176.0
VKLTNFLYLGNAE----------TAKNRDVLKKYSISHVINVTSNL-------PNTF--EEDPNMRYLRISADDNASHNLtKFFPEAISFIDDARRNDSA
. ... |.||..           .|.. . ||.. |..|.|.|.         || .  .|.....||..  .|.   .| . ..|.. ||..|....  
dyinanlilgsrpiatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpeleklgiqylhlpwpDhgvpdl.elllellefirealkeggp

CLVHCLAGISRSVTICLAYLMKT-EMCTLDSAYEWVQKRNA-SIAPNFHFMGQLTDYEKML
 |||| |||.|. |...|||...    ... |...|...    . ...... .| ..|..|
vlVHCsaGigRtgtlvaayllelekglsveealalvreqRplgavqtpeQyrflyefelll
0036941 (Phosphotyrosine protein) phosphatases II 186-326 1.2e-20 69.4 In-house 20-277 (297) alignment 
Range on Protein: 186-326
Range on HMM: 20-277/297.0
VKLTNFLYLGNAETAKNRDVLK----------------------------------------------------------KYSISHVINVTSNLPNTF--
 .|...|.||. ..|.. . |.                                                          .. .......|.  .. .  
eellpllllgslsvallpenleknRykdilpydhtRVklddegsdYinAsyvdgydlkrkfIatqgPlpntvedFWrmvweqnvtvIvmltelvelgrek

-----------------------------EEDPNMRYLRISA--------------DDNASHNLTKFFPEAISFIDDARR------NDSACLVHCLAGIS
                             ..|  .|.|...                .   |..   . . ..||. .|.      ...  |||| ||..
caqywpleegesltygdftvtllsvevvllddytlrtlevtdtgngesrtvthfhytgwpdhgvpespaslldfielvrkvlkllpsggpvlVHCsaGvg

RSVTICLAYLM--------KTEMCTLDSAYEWVQKRNASIAPNFHFMGQLTDYEKMLG
|| |...|.||        |.. ... .|. .. .. . . ... .. .| ... .| 
RsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyeallell
subfamily_DSP14_pd Subfamily DSP14 187-329 1.3e-40 132.9 In-house 9-148 (157) alignment 
Range on Protein: 187-329
Range on HMM: 9-148/157.0
KLTNFLYLGnAETAKNRDVLKKYSISHVINVTSNLPNtfEEDPNMRYLRISADDNASHNLTKFFPEAISFIDDARRNDSACLVHCLAGISRSVTICLAYL
..|. |.|. . .|.....|||. |...|||| .|||  .. ........ ..|| ...|.|.| |..  |....... ..|||| ||.||| ..|||||
qitpsLfls.gvaalskellkkkkitliinvtvelpn..tklkdiervkvpveDnpeaklakhfdevadkieevkkkggktlvhCvaGvSRSAslclayl

MKTEMCTLDSAYEWVQKRNASIAPNFHFMGQLTDYEKMLGLNS
||.|  .|  ||..|...   | ||  |  || |||| |  .|
mkyeklsLreayklvksaRpiirPNvGFwkqlidyEkklkgks
subfamily_DSP19_pd Subfamily DSP19 187-324 2.4e-38 125.8 In-house 14-149 (152) alignment 
Range on Protein: 187-324
Range on HMM: 14-149/152.0
KLTNFLYLGNAETAKNRDVLKKYSISHVINVTSNLPNTFEEDpnMRYLRISADDNASHNLTKFFPEAISFIDDARRNDSACLVHCLAGISRSVTICLAYL
.... ||||  ..|.... ||.  | |..||. ..||.| .|  . || |.  |.  ..|.....||. ||..||..| | |||| ||.|||... .|||
eveprlylgsqdvaadkeilkekkitHilnvatgvpnvfpkd..ftylsieilDlpetdllsylkealdFieearskdgavlvHCnAGvSRsasvviayl

MKTEMCTLDSAYEWVQKRNASIAPNFHFMGQLTDYEKM
||.|  .| .|.| |..   .| ||  |. ||..||. 
mkkeelsleealelvrearpcikPneGFikqLkeyeae
0049260 (Phosphotyrosine protein) phosphatases II 187-325 3.3e-29 96.9 In-house 10-149 (152) alignment 
Range on Protein: 187-325
Range on HMM: 10-149/152.0
KLTNFLYLGNAETAKNRDVLKKYSISHVINVTSNLPNTFE-EDPNMRYLRISADDNASHNLTKFFPEAISFIDD-ARRNDSACLVHCLAGISRSVTICLA
. . ....|.  .|.. . ||.. |......|. |..... ..  ..||..  .|.   .|. ...... ||.  |....  .|||| ||..|. |...|
efiatqgpgpntladfwrmlkelgittivmltellelgklkceqyiqylhlpwpDhgvpdlsqlllflllfieklaldkggpvlVHCsaGvgRtgtlvaa

YLMKtEMCTLDSAYEWVQKRNASIAPNFHFMGQLTDYEKML
|||.   ..|. |...|....  . ||.... .| ..||.|
ylml.lgvsleeavalvrekRpgavpnpgqlrflyefekll
subfamily_Dicty-DSP19-like_pd Subfamily Dicty-DSP19-like 187-324 4.6e-24 78.5 In-house 5-151 (154) alignment 
Range on Protein: 187-324
Range on HMM: 5-151/154.0
KLTNFLYLGNAETAKNRDVLKKYSISHVINVTSNLPNTFEED-------PNMRYLRISADDNASHNLTKFFPEAISFIDDAR--RNDSACLVHCLAGISR
| . |||..  ..| |.  |... | ...||    .| | ..         . ||..   |.. ..... .  |  |||||    ...  |||. .|.||
keaiflyissfdaalnkldlqlkniksilnvgiGinnlftdensdindgfiieylnlelfddvnfdiiekldkafefiddaiggvennkvlvhsdkGvsr

SVTICLAYLMKTEMCTLDSAYEWVQKRNASIAPNFHFMGQLTDYEKM
| .. ..|||.    .|  |.| ...    | ||  |. ||. .|| 
saallisylmdklkislslalellkdsryiikPnqGflkqleifeke
0051429 (Phosphotyrosine protein) phosphatases II 187-324 2.9e-19 65.2 In-house 19-223 (272) alignment 
Range on Protein: 187-324
Range on HMM: 19-223/272.0
KLTNFLYLGNAE---TAKNRDVLKKYSISHVINVTSNL----PNTFEEDPNMRYLRISADDNASHNLTKFF-----------------------------
 . ..||....    ||.. . ||.. |.......|       ... . |..|||...  |..    . ..                             
vkpgrlyrsggplpltaadfwrlkelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseellldyilrellltlllsage

-------------------PEAISFIDDARRnDSACLVHCLAGISRSVTICLAYLMKtEMCT--------------LDSAYEWVQKRNASIAPNFHFMGQ
                    . .....  .. . ..|||| ||..|. |.....|.  .  .              |. |.|..... . . .. ... .
arevmhlhytdwpdhgvpqeallellellld.ggpvlvHCsaGkdRTGtvvalllll.lgvsletivddYlltnlyleeaveelraqrpgavqteeqylf

LTDYEKM
| .... 
lyealle
subfamily_DSP12_pd Subfamily DSP12 188-326 9.7e-38 124.0 In-house 5-144 (155) alignment 
Range on Protein: 188-326
Range on HMM: 5-144/155.0
LTNFLYLGNAETAKNRDVLKKYSISHVINVTSN-LPNTFEEDPNMRYLRISADDNASHNLTKFFPEAISFIDDARRNDSACLVHCLAGISRSVTICLAYL
... ||||..|.... . ||...|.||. |... ||.  ..  ..... | ..|. . .. ....||..||..|. .. | |||| ||.||||||..|||
ilpglylggleavqeeellkelkithvlsvikeelpehklkkgkvstkfiqilDepeediLshldeavdFieealeeegavlvHCqagvSRSvtiviAYl

MKTEMCTLDSAYEWVQKRNASIAPNFHFMGQLTDYEKMLG
||.| . |..|.. |.. . .| ||  |. ||  .||| .
mkkeklslekAlklvkekkpeiepNegFleQLklfekmgc
0036282 (Phosphotyrosine protein) phosphatases II 188-325 6.4e-28 93.0 In-house 15-169 (174) alignment 
Range on Protein: 188-325
Range on HMM: 15-169/174.0
LTNFLYLGNAETAkNRDVLKKYSISHVINVTSNLPN-------------TFEEDPNMRYLRISADDNASHNLTKfFPEAISFIDDARRN--DSACLVHCL
 |. |..|.. .| . . ||...|..|.....  ..             ...|. ...||..  .|.   .|.. . |...|...|. .  .  .|||| 
itprliagqgpla.fwemlkelgittvvmlleekelglykcinywpelredlerlgiqylylpwpDhgvpdlsi.llefvkfveealsedpggpvlVHCs

AGISRSVTICLAYLMKTEMC-TLDSAYEWVQKRN---ASIAPNFHFMGQLTDYEKML
||..|. |...||||.. .. .|. |...|...      . ...... .| ..||.|
aGvgRtGtlvaaylmlrglleslvdaldlvrelRlqrpgmvqtpsQyrflyyfekll
0051082 (Phosphotyrosine protein) phosphatases II 188-322 3.6e-24 80.5 In-house 11-150 (151) alignment 
Range on Protein: 188-322
Range on HMM: 11-150/151.0
LTNFLYLGNAETAKNRDVLKKYSISHVINVTSNLPNTFEEDP----NMRYLRISADDNASHNLTKFFPEAISFIDDARRN-DSACLVHCLAGISRSVTIC
.|..||.... .| . . ||.. |....|..|  .. .. ..    ....|.|  .|.  ..|  .|.....|.. .... .  .|||| ||..|. |..
vtgglyrsggpladflellkelgiktivnlrseeergycpeylpelgievlhipildwpdpglplsfdavleflellldkkngpvlvHCsaGkgRTGtlv

LAYLMKtEMCTLDSAYEWVQKRNA-SIAPNFHFMGQLTDYE
..|||. ....|..|.|......  .. || .|. || ...
alylml.lgvsleealeeyrlkrpgvvqpnqqflfqlfall
0042113 (Phosphotyrosine protein) phosphatases II 188-324 7.9e-24 79.8 In-house 50-241 (245) alignment 
Range on Protein: 188-324
Range on HMM: 50-241/245.0
LTNFLYLGNAETAKNRD----VLKKYSISHVINVTSNLP--------------------------------------------NTFEEDPNMRYLRISAD
 |. ...... .... .     |... |......|.  .                                             ..|.  ...|.... .
itpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywplgesltygdftvtllseehlddytvrtlevtnlgddesrevihyhylpwp

DNASHNLTKFFPEAISFIDDARR--NDSACLVHCLAGISRSVTICLAYLM-----KTEMCTLDSAYEWVQKRNASIAPNFHFMGQLTDYEKM
|.   .|.. . ....|...|..  ..  .|||| ||..|. |...||||     |.   .|..|.......   . ...... .| .....
dhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylmleqlekelgvsleeavkelrsqRpgavqtpsqyrflyealle
PTEN_1 189-327 4.8e-30 99.8 In-house 45-193 (196) alignment 
Range on Protein: 189-327
Range on HMM: 45-193/196.0
TNFLYLGNAETA-KNRDVLKKYSISHVINVTSNLPN-------TFEEDPNMRYLRISADDNASHNLTKFFPEAISFIDDARRND--SACLVHCLAGISRS
  .||.|... . ...| ||. .| .|.|...  ..       ..... ...||... .|    .| ..| .. |||. .....   ..|||| ||..||
deglyrgslkdvaadldnlkedgitlvvnlseeeelsgrsydleeffksgveylhfpieDhgapslselfdicksfiewllsdpngnvVlVHCkaGlgRs

VTICLAYLMKTEMCTLDSAYEWVQKRNASIAPNFHFMGQLTDYEKMLGL
.|.. ||||...  | | | |.|...   .|||  .. .|  |...|  
GtvvaayLmykgkltadeAlelvrekRppgapnspsqerlleyfaella
subfamily_DSP15_pd Subfamily DSP15 190-324 2.9e-37 122.1 In-house 7-138 (151) alignment 
Range on Protein: 190-324
Range on HMM: 7-138/151.0
NFLYLGNAETAKNRDVLKKYSISHVINVTSNLPNTFEEdpnMRYLRISADDNASHNLTKFFPEAISFIDDARRNDSACLVHCLAGISRSVTICLAYLMKT
. ||||| . .|... ||.  |.|...|  |  . ...   ..|. |.|.| .| .|.||| |...|| ..| .. ..|||||||.|||||.. ||||  
pglylgnfrdskdeelLkeknithilsvhdnakkllkd...ieYkciaasDtpsaklskffkesvefihkcRlkeenvlvhClaGvsRsvtlvvaYlmtv

EMCTLDSAYEWVQKRNASIAPNFHFMGQLTDYEKM
       | | .... ..  ||| |  || .|||.
telnwrdalevikaaRsvanPnfGfkrqlkeyekt
subfamily_DSP3_pd Subfamily DSP3 190-325 1e-31 103.8 In-house 16-157 (162) alignment 
Range on Protein: 190-325
Range on HMM: 16-157/162.0
NFLYLGNAETAKNRDVLKKYSISHVINVTSN------LPNTFEEDPNMRYLRISADDNASHNLTKFFPEAISFIDDARRN-DSACLVHCLAGISRSVTIC
. ||.|....||... |||  | ||.| .          . | .| ...|| . .||. . .| |.| .| .|||.|  . ..  |||| .|.||| |. 
pklyvgdeavakdkskLkklGithvlnaaegrfskvdtgaefykdleikylGlevdDvpefdlskyFetaakfidealsqkegkvlvhcvvGvsRsatlv

LAYLMKTEMCTLDSAYEWVQKRnASIAPNFHFMGQLTDYEKML
||||| ..  || .| . |.|.  .| ||  |. ||..... |
layLmirrkmtlveairtvrkk.ReilPneGFlkqLaeldeel
DSPc Dual specificity phosphatase, catalytic domain 192-323 1.8e-40 132.9 Pfam-A 1-132 (133) alignment 
Range on Protein: 192-323
Range on HMM: 1-132/133.0
LYLGNAETAKnRDVLKKYSISHVINVTSNLPN-TFEEDPNMRYLRISADDNASHNLTKFFPEAISFIDDARRNDSACLVHCLAGISRSVTICLAYLMKTE
||||...||.  ..|.|..|..|||||.. ||  . .... .||||  .|. . ...|...||..||..|...   .|||| |||||| |...||||||.
lylgskstas.lalleklgitlvinvtkevpnnnaikkseieylripvedetetkiskeleeavefiekaeqkgkkvlVHCqaGisRSatliiaYlmktk

MCTLDSAYEWVQKRNASIAPNFHFMGQLTDYEK
 ..|..||| |..|  .| ||..|..|| .||.
nlslneAyefvkerrskispnagflrqLleyer
DSPc Dual specificity phosphatase, catalytic domain 192-323 1.8e-40 132.9 In-house 1-132 (133) alignment 
Range on Protein: 192-323
Range on HMM: 1-132/133.0
LYLGNAETAKnRDVLKKYSISHVINVTSNLPN-TFEEDPNMRYLRISADDNASHNLTKFFPEAISFIDDARRNDSACLVHCLAGISRSVTICLAYLMKTE
||||...||.  ..|.|..|..|||||.. ||  . .... .||||  .|. . ...|...||..||..|...   .|||| |||||| |...||||||.
lylgskstas.lalleklgitlvinvtkevpnnnaikkseieylripvedetetkiskeleeavefiekaeqkgkkvlVHCqaGisRSatliiaYlmktk

MCTLDSAYEWVQKRNASIAPNFHFMGQLTDYEK
 ..|..||| |..|  .| ||..|..|| .||.
nlslneAyefvkerrskispnagflrqLleyer
subfamily_STYX_pd Subfamily STYX 192-324 5.7e-24 78.1 In-house 19-156 (166) alignment 
Range on Protein: 192-324
Range on HMM: 19-156/166.0
LYLGNAETAKN--RDVLKKYSISHVINVTSNLPNTFEE---DPNMRYLRISADDNASHNLTKFFPEAISFIDDARRNDSACLVHCLAGISRSVTICLAYL
|.||   .|..   .||||  |.|.. .  |.  ..     . ..||| .   ||.  |. ...|.  .||||. ..    |||  |||||| .. .||.
lflgpysaamksklevlkkhgithivcirqnieanlikpnfpdrfrylvldvadntveniirylptvkefiddslqkggkvlvhgnagisrsaalviayi

MKTEMCTLDSAYEWVQKRNASIAPNFHFMGQLTDYEKM
|.|      .|. .||.|   |.||  |. ||..|| .
metyglkyreafayvqerrfcinpnegfvsqlkeyeai
subfamily_Sponge-DSP-Subfam1_pd Subfamily Sponge-DSP-Subfam1 192-325 4.2e-23 75.0 In-house 6-141 (145) alignment 
Range on Protein: 192-325
Range on HMM: 6-141/145.0
LYLGNAETAKNRDVLKKYSISHVINVT--SNLPNTFEEDPNMRYLRISADDNASHNLTKFFPEAISFIDDARRNDSACLVHCLAGISRSVTICLAYLMKT
|| | | .|..  .|..  || ..|..  | .  .     ..  | |.|.|  |..|.. | |   |||  . . .  .|||.||.|||||. .|.||| 
lyvgsalhandvptlqelgisrivnmaagslvasqelksesieillitaedlesydlsqhfdevtdfidkgkeegagvfvhcmagvsrsvtvsvaflmky

EMCTLDSAYEWVQKRNASIAPNFHFMGQLTDYEKML
   ||  |   |. .     || .|. .| . || |
cnmtlseaarqvrsnrllaypnvtflknllnlekql
0040439 (Phosphotyrosine protein) phosphatases II 198-326 1.3e-24 82.6 In-house 66-246 (249) alignment 
Range on Protein: 198-326
Range on HMM: 66-246/249.0
ETAKNRDVLKKYSISHVINVTSNLPNTF-----------------------------------------EEDPNMRYLRISADDNASHNLTKFFPEAISF
 ...... |... |......||  .. .                                         ....  ..| |   |   |.. ..|.....|
tvedfwrmlwelgitvivmLtslvelgrekcaqywplggsleygdftvtllsvevkddytvrtleltnlydgesrtvlhiqytdwpdhgvppsfedlldf

IDDARR------NDSACLVHCLAGISRSVTICLAYLM-----KTEMCTLDSAYEWVQKRNASIAPNFHFMGQLTDYEKMLG
|. .|       ... .|||| ||..|. |...||||     |.   .|..|.......   . .|.... .| .....| 
ieavrkaleelpkggpvlVHCsaGvgRtGtfiaaylmleqlekelgvdleeavkllrsqRpgavqnpeqyrflyeallell
0045450 (Phosphotyrosine protein) phosphatases II 201-325 2.5e-24 82.0 In-house 58-303 (307) alignment 
Range on Protein: 201-325
Range on HMM: 58-303/307.0
KNR----------------------------------------------------------------DVLKKYSISHVINVTSNLPNTFE----------
|||                                                                  |... .......|.  ....|          
knrykdilpydhtRVklssldgsledsdYiNAsyvrvpllllldgydlkrkfIatqgPlpetvedFwrmlweqgvtvivmltelvelgrekcaqywPdeg

----------------EDPNMRYLRISADDN-----------------ASHNLTKFFPEAISFIDDARR------NDSACLVHCLAGISRSVTICLAYLM
                ..... ....   |.                   |.. ..| |...||. .|.      ... .|||| ||..|. |...||||
eeltygnftvtllseehldgytvrtlevtdldgtgesrtvthfhytgwpdhgvppsfeelldfieevrkaleelpkggpvlVHCsaGvgRtGtfiaaylm

KTEM--------CTLDSAYEWVQKRNASIAPNFHFMGQLTDYEKML
.. .        ..|..|.......   . .|.... .| .....|
lrqlekegtlldvdlleavkllreqRpgavqnpeqyrflyeallel
0040438 (Phosphotyrosine protein) phosphatases II 201-329 4.4e-21 70.9 In-house 46-279 (317) alignment 
Range on Protein: 201-329
Range on HMM: 46-279/317.0
KNRD-------------------------------------------------------VLKKYSISHVINVTSNLPNT---------------------
|||                                                         .... .......|.  ..                      
knrypdilpydhsRVkLsplggdldsdYInAsyvdgpnlkrkfIatqgPlpntvedFwrmvweqgvtvivmLteleelgrekcaqYwplgetltygdftv

-----FEeDPNMRYLRISADDN----------------ASHNLTKFFPEAISFIDDARRN----DSACLVHCLAGISRSVTICLAYLM-----KTEMCTL
     .| .... ....   |.                  |.. . . . ..|.. .|..    .. .|||| ||..|. |...||||     |.. ...
tllseee.lagitlrtlevedlgdsesrtvthfhytgWpdhgvppspdllldfleavrealedpggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdv

DSAYEWVQKRNASIAPNFHFMGQLTDYEKMLGLNS
..|....... . . ... .. .| |.. .. .. 
eeavkelreqRpgavqtpeqyrflydalleylkrk
0039614 (Phosphotyrosine protein) phosphatases II 204-325 4.8e-20 67.7 In-house 119-288 (297) alignment 
Range on Protein: 204-325
Range on HMM: 119-288/297.0
DVLKKYSISHVINVTSNLPNTF-----------------------EEDPNMR-----------------YLRISADDNASHNLTKFFPEAISFIDDARR-
  .... .......|.  ..                         |.....                  .. ..  |.   .... . |.. ....|.. 
rmvweqgvtvivmLtklvelgrkcaqywpeeggtygdftvtllkvehldgytvrtlevtnngesrtvthfqytgwpdhgvppslellleflelvrealae

--NDSACLVHCLAGISRSVTICLAYLM-----KTEMCTLDSAYEWVQKRNASIAPNFHFMGQLTDYEKML
  ..  .|||| ||..|. |...||||     |.   ....|.......   . ...... .| |....|
lpkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavqtpsqyrflydallel
subfamily_DSP23_pd Subfamily DSP23 204-308 1.7e-09 32.5 In-house 25-129 (148) alignment 
Range on Protein: 204-308
Range on HMM: 25-129/148.0
DVLKKYSISHVINVTSNLPNTFEEDPNMRYLRISADDNASHNLTKfFPEAISFIDDARRNDSACLVHCLAGISRSVTICLAYLMKTE-MCTLDSAYEWVQ
  |    . ... .| . .   |  ||. . |.  ||     | .   | .  ...|  .. |  |||| |  |. |.   ||.| . ... ..  |  .
rylldlgvrylvslteegrphveatpnltlvrlriddyhppaleq.vvefvrvveeaeekneavsvhcllgrgrtgtmlacylvkerklaaaeaiaevrr

KRNASI
.|  |.
lrpgsv
0043336 (Phosphotyrosine protein) phosphatases II 205-323 9.9e-16 53.5 In-house 107-274 (278) alignment 
Range on Protein: 205-323
Range on HMM: 107-274/278.0
VLKKYSISHVINVTSNLPNTF---------------------------------------------EEDPNMRYLRISaDDNASHNLTKFFPEAISFIDD
 .... .......|.   .                                                .   . || .  |... ..|. ..     ... 
mvwelgvttivmLtelvelgrvkcaqYwpggsltygdftvtllkeehlddytvrtlevtnlgdgesrtvthyhylgwp.dhgvpeslsllldflkavrea

ARRNDSACLVHCLAGISRSVTICLAYLM-----KTEMCTLDSAYEWVQKRNASIAPNFHFMGQLTDYEK
 . .... |||| ||..|. |....||.     |.   .|..|....... ... ... .. .| ....
ledsngpvlVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqRpgavqtpsqyrflyeall
subfamily_RNGTT_pd Subfamily RNGTT 206-309 8.8e-06 19.5 In-house 50-159 (189) alignment 
Range on Protein: 206-309
Range on HMM: 50-159/189.0
LKKYSISHVINVTSNLPNTFEEDP---NMRYLRISADDNA---SHNLTKFFPEAIS-FIDdaRRNDSACLVHCLAGISRSVTICLAYLMKTEMCTLDSAY
..|. .  ||..| . .   .|.    ...| ...   .    ... .| | . .. |..  .. ..   |||  |  |.  .  .||...| . ...| 
tlkvklglvidltntsryYdkeelekegikyvklqcagkgeaPeaeqvkefiklveeffk..knpeevigvhCthGfnRtGFlivsyLvekedwsveaav

EWV-QKRNASIA
.   . |.  | 
alFakaRppGiy
subfamily_PTPMT1_pd Subfamily PTPMT1 207-324 3.3e-15 51.0 In-house 43-167 (171) alignment 
Range on Protein: 207-324
Range on HMM: 43-167/171.0
KKYSISHVINVTSNLP--------NTFEEDpNMRYLRISADDNASHNLTKFFPEAISFIDDARRNDSACLVHCLAGISRSVTICLAYLMKTEMCTLDSAY
.|. .  |......          .....  .. .|...  | . .  ..   ... ||.. . . .   ||| || .|| |.  .||||.| .....| 
ekenvkavvslneeyelkalansteewkkl.gveqlqlatvDfteapdleklekgvefiekvaskgkrvYvHCkaGrgRsatlvacylmkkeklspeeAl

EWVQKRNASIAPNFHFMGQLTDYEKM
. ..|.   |  . . . .|. ||. 
kalkkkRkiirlakkqwkalqeyeek
0038934 (Phosphotyrosine protein) phosphatases II 208-323 7.4e-17 57.1 In-house 54-174 (194) alignment 
Range on Protein: 208-323
Range on HMM: 54-174/194.0
KYSISHVINVTSN---LPNTFEEDPNMRYLRISADDN---ASHNLTKFFPEAISFIDdARRNDSACLVHCLAGISRSVTICLAYLMKTEMCTLDSAYEWV
.. . .||..| .      .  |. ...||..   |     | .... | ... ..  .. .. ...||| ||..|. |.. |||...  .... |....
nvklglvidltnteryYdpeefekagieylklpfpddgtvPsleillrfldlvdefl.nedpggvvaVHCkaGlgRtGtlvaaYLiyrlgmsaeeAialf

QKRNASIAPNFHFMGQLTDYEK
. .  .. || ... .|  . |
rekRpgaipnqdyleallkryk
subfamily_MSG5_pd Subfamily MSG5 209-330 1.1e-16 54.4 In-house 46-165 (165) alignment 
Range on Protein: 209-330
Range on HMM: 46-165/165.0
YSISHVINVTSNLPNTFEEDPNMRYLRISADDNAshNLTKFFPEAISFIDDARRNDSACLVHCLAGISRSVTICLAYLMKTEMCTLDSAYEWVQKRNASI
 |.  ||||. ....     | ..|  |  . ..  ...| ...  . |  |. .    ||||  |.||| .. .||.||    .|  ||. .. .   |
lsfdlvinvakeindlellvpavkyyhiewehds..kivkdlsrltriihaatskrkkilvhcqcglsrsaslivayimkyynlslrdaydklksvaddi

APNFHFMGQLTDYEKMLGLNSN
.|.. .. || ..| .|  .||
spsiglifqlmewevalskksn
PTPlike_phytase Inositol hexakisphosphate 221-287 7.9e-06 20.5 Pfam-A 83-147 (149) alignment 
Range on Protein: 221-287
Range on HMM: 83-147/149.0
LPNTFEEDPNMRYLRISADDNASHNlTKFFPEAISFIDDArRNDSACLVHCLAGISRSVTICLAYLM
  ....| ....| || . |. . .  . . . ...| ..  .|.| ...| ||  |. |    . .
yeeelaegfgvkYvRipitdeqape.eedvDafvrliksl.prdtalvfnCqaGrgRTTtamviadL
PTPlike_phytase Inositol hexakisphosphate 221-287 7.9e-06 20.5 In-house 83-147 (149) alignment 
Range on Protein: 221-287
Range on HMM: 83-147/149.0
LPNTFEEDPNMRYLRISADDNASHNlTKFFPEAISFIDDArRNDSACLVHCLAGISRSVTICLAYLM
  ....| ....| || . |. . .  . . . ...| ..  .|.| ...| ||  |. |    . .
yeeelaegfgvkYvRipitdeqape.eedvDafvrliksl.prdtalvfnCqaGrgRTTtamviadL
0048567 (Phosphotyrosine protein) phosphatases II 224-310 2.5e-08 28.4 In-house 32-123 (157) alignment 
Range on Protein: 224-310
Range on HMM: 32-123/157.0
TFEEDPNMRYLRISADDNASH--NLTKFFPEAISFIDDARRNDSACLVHCLAGI---SRSVTICLAYLMKTEMCTLDSAYEWVQKRNASIAP
 |  | .. |.   .|.   .   |..|.  . .|... . .. |  ||| ||    .|..|.. .||..    | . |.....  . .. |
yFsiddglvyedfffdfGPlnlailyrFilklnkflkilelagkaiavhckaglkkrgrtatLigcYlilhlgftpeeaiaplrivrpgsvp
0051299 (Phosphotyrosine protein) phosphatases II 226-312 1.5e-11 39.7 In-house 159-272 (288) alignment 
Range on Protein: 226-312
Range on HMM: 159-272/288.0
EEDPNMRYLRISA----------------------DDNASHNLTKFFPEAISFIDDARRNDSACLVHCLAGISRSVTICLAYLM-----KTEMCTLDSAY
..|  .|.|...                       |... .... ..     ...  . ... ..||| ||..|. |.....|.     |...... .|.
lddytvrtlevtnldlldgdgesrtvthfhytnwpdhgvpdspellldflrlvrkalasgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleav

EWVQKRNASIAPNF
... ..   . ...
krlreqRpgmvqtp
0050432 (Phosphotyrosine protein) phosphatases II 226-305 5.2e-11 37.9 In-house 178-278 (308) alignment 
Range on Protein: 226-305
Range on HMM: 178-278/308.0
EEDPNMRYLRISA------------------DDNASHNlTKFFPEAISFIDDARrNDSACLVHCLAGISRSVTICLAYLM-----KTEMCTLDSAYEWVQ
..|  .|.|...                   |... .. .. . . . .... . ... ..||| ||..|. |.....|.     |. .... .|. .. 
lddytvrtleltnlgdgesrtvthfhytnWpdhgvPps.peilldflelvrksl.pggpivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkklR

KRN
.. 
eqR
0046845 (Phosphotyrosine protein) phosphatases II 238-304 5.5e-10 34.6 In-house 175-252 (284) alignment 
Range on Protein: 238-304
Range on HMM: 175-252/284.0
ADDNASHNLTKFFPEAISFIDDARRN---DSACLVHCLAGISRSVTICLAYLMKTE--------MCTLDSAYEWVQKR
  |.     .. . | . .......|   ..  .||| ||..|. |.....|...         .... .|. .. ..
wpdhgvppspedlleflrlvrellenlpgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreq
0047943 (Phosphotyrosine protein) phosphatases II 243-318 1.5e-12 43.0 In-house 178-264 (273) alignment 
Range on Protein: 243-318
Range on HMM: 178-264/273.0
SHNLTKFFPEAISFIDDARR------NDSACLVHCLAGISRSVTICLAYLM-----KTEMCTLDSAYEWVQKRNASIAPNFHFMGQL
 |.    . . ..||...|.      ...  .||| ||..|. |.....|.     |. . ....|. .....   . ... .. .|
dhgvppslesllefielvrkalealpsngpvvVHCsaGvgRtgtfialdllldqlekeggvdvleavkllrsqRpgmvqtpeqyrfl
PTPc_DSPc_SM00012 253-292 1.2e-06 24.0 In-house 22-67 (105) alignment 
Range on Protein: 253-292
Range on HMM: 22-67/105.0
AISFIDDARRND------SACLVHCLAGISRSVTICLAYLMKTEMC
 ...... ..|       . ..||| ||..|. |.......   ..
ilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqle