Synonym: CELE_M04G7.2, CELE_M04G7.2
Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
---|---|---|---|---|---|---|---|---|---|
subfamily_Cele-PTP-16_pd | Subfamily Cele-PTP-16 | 241-519 | 1.3e-25 | 84.6 | In-house | 3-276 (303) | alignment | ||
Range on Protein: 241-519
Range on HMM: 3-276/303.0
EETREAYRKLFKDFAMSSQKMTLDDFKQEFSNLPgdpPSdlCTVFNHPVNNKKNRYSNIPCLDISRVQLKfkmpnknSTDYIHANYIRSPFLKRGyILTQ
|| .. .. | |.. ... ..|.. | || || . . | .|||. .. ||| |.|.| . ||||.|. |. ||||
eekkqkwkllakrtldedaniavnefekvvsylp...ps..vsknqfvknmdknrfvdvicldhskvkls.......dssyihasyleldsskka.iltq
GPKKETRADFWRMIWQENTTAIVMLCQFLETNREKCAEYFPRNAHcCLQFDKFSV---NYEDSTVNKSLVTTRLNLSYEGETRLITHWLWKEWPDWQVPE
| | ||||.|| ... ...| | .. |||| |.|.. |. .. . . | | .| .. .|.|| ..|
lplshtaadfwqmiieqkvkcvlllltdseydklggdsvfprnqd.flkfeersirvgefkrvelgdgwvlkvlsvsngdyksflhvhhykawphnsips
S-SEVMLK-------ILRKIrARSTPPVIHCSAGVGRSGTLMAVEIALQSIHTHFTLPDIKQIVSHLRvTGRAASVQTLQQYMLIWKVLL
| ..| .||| . |||.| .|.||.||. | | |.|. . |. . . .| || .|| | |. ... .|
dgspkfvkqiwqlqsvlrky.sdstptvymslsgcgragtfalfetahlslhseqasldlvkclenvr.ngrlhavqnlsqfsvvytlla
|
|||||||||
subfamily_Cele-PTP-14_pd | Subfamily Cele-PTP-14 | 243-531 | 6.9e-42 | 138.1 | In-house | 6-299 (310) | alignment | ||
Range on Protein: 243-531
Range on HMM: 6-299/310.0
TREAYRKLFKDFAMSSQKMTLDDFKQEFSNLPGDPPSDLcTVFNHPVNNKKNRYSNIPCLDISRVQLKFKmpNKNSTDYIHANYIRSPFLKRGYILTQGP
| | ...| ....|. .. . ... .| . | | | . . .|||||.. ||| |||.|| . |||||||... .|. .| .|||
hhlkylkalenfiiateklgieglvkqyrkldakqdssl.tyeaykkymhknrysdvvcldtsrvklkid..ksryedyihanyvktnylrstficsqgp
KKETRADFWRMIWQENTTAIVMLCQFLETNREKCAEYFPR----NAHCCLQFDKFSVNYEDSTVNKSLVTT-RLNLSYEG-----ETRLITHWLWKEWPD
. | ||||||.|| . .|..||. | | || |.| ... |.. ..| |. . . || |. . . .. | .|||
lqhtiidfwrmifqeraesilllckvgeegrpkcvgywpslgvtetygcirvtnlsesseefeicnlavtfvpdnvpvdeqpanlkelrvslikwpnwpd
WQVPESS--EVMLKILRKIraRSTPPVIHCSAGVGRSGTLMAVEIALQSIHTHFTLpDIKQIVSHLRVtGRAASVQTLQQYMLIWKVLLDFGVAYKQITE
||. | ..| .. | | |.|||||..| ....|...... .. . |.......|. || .|| ||..| .| . | . ....|
rgvpdekchtvpqrllaqv..rhgpcvvhcsagkdrlyvvvalklkidkldrglkv.daeevktellk.sraiciqtelqyliidrvriifargetevae
E
.
k
|
|||||||||
subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 244-521 | 1.9e-56 | 186.5 | In-house | 7-289 (298) | alignment | ||
Range on Protein: 244-521
Range on HMM: 7-289/298.0
REAYRKLFKDFAMSSQKMTLDDFKQEFSNLPGDPP---SDLCTVFNHPVNNKKNRYSNIPCLDISRVQLKFKMpNKNSTDYIHANYIRSPFLKRGYILTQ
| ...... .| ..|..| ...|| .| .. .| ..| |.|||||..| || ||| |. . ... .||| | .. . . .|.||
aedlkaalqklaavkkkkkltgyalefqrlnsvsseieeeekevarkpenkkkNRyadiialdssRvvLeked.adeesdYiNAsflhaykgrnafiatq
GPKKETRADFWRMIWQENTTAIVMLCQFLETNREKCAEYFPRNAHccLQFDKFSVNYEDSTVNKSLVTTRLNLSYEG--ETRLITHWLWKEWPDWQVPES
.| .|| .|||||...|. ..|||| . |... |. .|.| . . ......|. . . |....|..| . ..| . . . .||| .|||
aPltetvedFWrmvteedigtiVmltnleeldktkyhkywPdegk..etygeitvsllskeefadlivrklkvskkkeekerevrqlhftsWpdkgvpen
SEVMLKILRKIRARS-----TPPVIHCSAGVGRSGTLMAVEIALQSIHTHFTLpDIKQIVSHLRVTgRAASVQTLQQYMLIWKVLLDF
.. .|..|||.|| .| ...|||||||||| .|.. |. ... .. |. |.| ||.. |...||| .||. |... |..
atsvldllrkvrasqqqagnkpvivqCsaGvgRsGtfiaidsvlervkkeqvv.DvfqvvkvlRkk.rpgavqteeqYvfiyeavlea
|
|||||||||
subfamily_PTPRB_pd | Subfamily PTPRB | 246-521 | 4.8e-68 | 224.3 | In-house | 7-284 (293) | alignment | ||
Range on Protein: 246-521
Range on HMM: 7-284/293.0
AYRKLFKDFAMSSQKMTLDDFKQEFSNLPGDPPSDLCTVFNHPVNNKKNRYSNIPCLDISRVQLKfKMPNKNSTDYIHANYIRSPFLKRGYILTQGPKKE
. |... .. .. . |..|...| . ... ...||..||||.|| | |||.|. .. .....||| ||||. .| .| |||| |
iklekfeehvkkmkadsdlrfseeyeelkavgkdqavkaaelavnraknrytnilpydhsrvkLa.alkdesgsDYinanyipgynsprefiatqGPlpe
TRADFWRMIWQENTTAIVMLCQFLETNREKCAEYFPRNAHCClQFDKFSVNYEDSTVNKSLVTTRLNLSYEGETRLITHWLWKEWPDWQVPESSEVMLKI
|. |||||.|......|||| | .| ..|| ||.|.. . . .. . .|. ... . |. |... | |.| .... .. |||. |||... .|..
tvddfWrmvwekkssiivmltqlvekgkvkCeeYWPadeepv.lyGdikvtlvaeeeledwvirelkiekekeerkvrqyhftsWpdhgvPektktlldf
LRKIRARS------TPPVIHCSAGVGRSGTLMAVEIALQSIHTHFTLpDIKQIVSHLRVTgRAASVQTLQQYMLIWKVLLDF
.|..| . .| |.||||||||.||..|.. ||.|... .. || ||..|| . |. ||| .||. | ...||.
vrtvreaiektaskrPivvhCsaGvGRtGtfialdrllqaieeedyv.difgivaelRee.RnllvqtekqYifihqcvldl
|
|||||||||
subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 249-528 | 1.6e-59 | 195.9 | In-house | 12-289 (290) | alignment | ||
Range on Protein: 249-528
Range on HMM: 12-289/290.0
KLFKDFAMSSQKMTLDDFKQEFSN--LPGDPPSDL-CTVFNHPVNNKKNRYSNIPCLDISRVQLKfkmpNKNSTDYIHANYIRSpfLKRGYILTQGPKKE
. |. || . |.. |.. .|. . | | | .|.. . ||||| ...| |..|| || . ||.||||.. || .|||||. |.
eafekfasdvvkknvdelakeyleklkpylpvqylerkifdkntefkknrykdvvcndktrvilk....dGydGdyvhanyvkG..lkamfiltqGalkd
TRADFWRMIWQENTTAIVMLCQFLETNREKCAEYFPRNAHCCLQFDKFSVNYEDSTVNKSLVTTR-L--NLSYEGETRLITHWLWKEWPDWQVPESSEVM
| |.|||. ||...||||||. .| . ||..|.| .. | | ...| .. . . . . | .| . |. | ||| |. |. .
tvidiwrmvlqekvaaivmlceliedGkakceqyypekeGevltfGeitvlcseeddkdaniikktlsvrdkdsGkehklkhlkikswpdksvalstlal
LKILRKIRARSTPPVIHCSAGVGRSGTLMAVEIALQSIHTHFTLpDIKQIVSHLRVtGRAASVQTLQQYMLIWKVLLDFGVAYKQI
|..|| .| | | |.|||||.||.||..|.|..|| . | |. ..| || |..||| ||... ..|||.|...| |
lrtlrilrkasGpvvvhcsaGiGrtGtfvaievglqilldGkel.dlldlvralrn.srlnsvqvdiqylalveilldlGkdfkyi
|
|||||||||
subfamily_Sponge-PTP6_pd | Subfamily Sponge-PTP6 | 250-540 | 2.7e-41 | 136.5 | In-house | 6-299 (439) | alignment | ||
Range on Protein: 250-540
Range on HMM: 6-299/439.0
LFKDFAMSSQKMTLDDFKQEFSNLPGDPPSDLC--TVFNHPVNNKKNRYSNIPCLDISRVQLKfKMPNKNSTDYIHANYIRSPFLKRGYILTQGPKKETR
|.. .| . ||..| .. | | .. . .. |||| .. .| .|| |. ..| . || ||||. . .. || ||||||||
efqehvekldknkqeifkeifekinstspdyaciaslaaqeydqtknrykdvgafdhtrvtlq.eipgvphshyinanyikGyyddklyiatqgpkkett
ADFWRMIWQENTTAIVMLCQFLETNRekcaeYFPRNAHCC-----LQFDKfSVNYEDSTVNKSLVTTRLNLSYEgeTRLITHWLWKEWPDWQVPESSEVM
||||......|. ||||....|. . |.| .|..| .. |. .. . .. | . . . | . .. . ||| .|| . .
ddfwrlviekktvtivmltnlvesyk.....ywpsdaevcygdiavrvdr.nielpnyvirgfkvfnerdttek..ertvlqfhyiawpdknvpaqashv
LKILRKIRA-----RSTPPVIHCSAGVGRSGTLMAVEIALQSIHTHFTLpDIKQIVSHLRVtGRAASVQTLQQYMLIWKVLLDfGVAYKQITEELAE---
|. || | . | |.||||||||.||..|..|||. ... . ||| ||. || | ||.| ||..|.. .|. . | .|. . |
ldflrainsandkeeygpvvvhcsagvGrtGtiialdialeqlklenkv.dikgivkvlrk.qrkqmvqalcqyvfiynavle.divyGdiavtidefkk
KFNSTY
.||. .
efnagf
|
|||||||||
subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 251-520 | 2.2e-49 | 162.9 | In-house | 7-281 (290) | alignment | ||
Range on Protein: 251-520
Range on HMM: 7-281/290.0
FKDFAMSSQKMTLDDFKQEFSNLPGDPPSDLCTVFNHPVNNKKNRYSNIPCLDISRVQLKFKMPNKN-STDYIHANYIRSPFLKRGYILTQGPKKETRAD
| .| . .. . |...| | . || . . |...||..|| | |. |. . .|. . .||.| || |. ||.|||| ..| .|
fgefvanghakgnegfrnqfkmldsgesehtvtvgltssnkllnRfanivvyddnritLrpisghkDCtneyinAcyikgykekkqyiatqgpvsntlvd
FWRMIWQENTTAIVMLCQFLETNREKCAEYFPRNaHCCLqFDKFSVNY-EDSTVNkSLVTTRLNLSYE---GETRLITHWLWKEWPDWQ-VPESSEVMLK
||..||||..|.||||.. | ...|| |.| . ...||.. ...|.| . ....|.. . |... .|.. . |.. |.. . ..|
FWkliwqekvtiivmltniieegkvkCqqYWpds.dtka.ygefsikllneetln.eyierklevknknsagakqsvtqyqitnwdstgkvtnpqtillv
ILRKIR----ARSTPPVIHCSAGVGRSGTLMAVEIALQSIHTHFTLpDIKQIVSHLRVTgRAASVQTLQQYMLIWKVLLD
| . .. |. |.|||..||||....|...... .| |. |.. ..|. . |||| ||| .| ...|
ieemyktqrkrgntsivvHCSdtvgrsavfcaaattinkcktegvi.dvfqvlksqRiq.kpgsvqtvqqyqgifqivlt
|
|||||||||
subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 251-521 | 2.8e-47 | 156.1 | In-house | 7-277 (287) | alignment | ||
Range on Protein: 251-521
Range on HMM: 7-277/287.0
FKDFAMSSQKMTLDDFKQEFSNLPG-DPPSDLCTVFNHPVNNKKNRYSNIPCLDISRVQLKfkmpnKNSTDYIHANYIRSPFLKRGYILTQGPKKETRAD
| .|. . .. ..||. | | . | |. . |..|||...| | || || .. ||| | .| . |. .|....| .| .
fgefvakghakgnegfknqftvleqvtqredevthniasqnkdknRltqilvpdnyrvllk.....gehpdyinavfidgykekkafiiaesPmfntarn
FWRMIWQENTTAIVMLCQFLETNREKCAEYFPRNAHccLQFDKFSVNYEDSTVNKSLVTTRLNLSYEG---ETRLITHWLWKEWPDWQ-VPESSEVMLKI
||..|...| |||||||| |...|.| .|.| .. . . ..... . .||.. . .|.. .. ... .. . .|.. |.| ..| |
fWkliddrnvtaivmlcqekendeevcyqyWpeeks..vvlGeyniellneevnagyierklevknknkagdkqqvkqyqitnWdstgkvtepqtillvi
LRKIRAR----STPPVIHCSAGVGRSGTLMAVEIALQSIHTHFTLpDIKQIVSHLRVTgRAASVQTLQQYMLIWKVLLDF
...... |. |.|||..||||....|...... .| .. |. |.. . |. . |||| .||. | ...| .
eemyktqrkrgntsivvhCsdtvGrsamfcaaattinkckteGvi.Dvfqvlksqriq.kpgsvqtveqykfindivley
|
|||||||||
subfamily_PTPRD_pd | Subfamily PTPRD | 252-521 | 2e-69 | 229.7 | In-house | 11-280 (564) | alignment | ||
Range on Protein: 252-521
Range on HMM: 11-280/564.0
KDFAMSSQKMTLDDFKQEFSNLPGDpPSDLCTVFNHPVNNKKNRYSNIPCLDISRVQLKfKMPNKNSTDYIHANYIRSPFLKRGYILTQGPKKETRADFW
|.. . .. .|..|. .. .. ... |.|.| .||||.|| | ||| |. |.......||| |..| . .. || ||||..|| .|||
kehvaklkansdlkfeeeykkieeg.qqftweaankpaNkaKNRyanivaYdhsRVvLs.kvegdegsDYINAsfidgyrkrkayIAtqgPlaetiedFW
RMIWQENTTAIVMLCQFLETNREKCAEYFPRNaHcCLQFDKFSVNYEDSTVNKSLVTTRLNL--SYEGETRLITHWLWKEWPDWQVPESSEVMLKILRKI
||.|..|.. |||| . | ...||..|.| . . ..... |. |... . . . ..| . . |.| .... . .||| |||| . .|...||.
RmvweqnsstiVmltkleEkgkvkchkYWPek.g.tetygeltVtleeeeeladyeirtfklkkkkssesreVrqFhFtsWPdhgvpesatslLdlirkv
RAR----STPPVIHCSAGVGRSGTLMAVEIALQSIHTHFTLpDIKQIVSHLRvTGRAASVQTLQQYMLIWKVLLDF
|| . | |.||||||||.|| ..... |. |.. |. || |.|..|| . | | ||| .||. |....|..
ralnepdagPivVhCSaGVGRTGtfividamlerikeektv.Diyqyvkalr.kqRnamVqteeQYiFiheailea
|
|||||||||
0040438 | (Phosphotyrosine protein) phosphatases II | 253-523 | 1.5e-78 | 259.6 | In-house | 7-277 (317) | alignment | ||
Range on Protein: 253-523
Range on HMM: 7-277/317.0
DFAMSSQKMTLDDFKQEFSNLPGDPPSdLCTVFNHPVNNKKNRYSNIPCLDISRVQLKFkMPNKNSTDYIHANYIRSPFLKRGYILTQGPKKETRADFWR
.. . |. ...|| .|. ... ..|...|.| .||||..|...| |||.|. ... ...|||.|.|. | ||| .|.||||...| .||||
lalldllksdftalleefedllslkld.tysvaelpenkdknrypdilpydhsRVkLsp.lggdldsdYInAsyvdgpnlkrkfIatqgPlpntvedFwr
MIWQENTTAIVMLCQFLETNREKCAEYFPRnaHCCLQFDKFSVNYEDSTVNKSLVTTRLNLS--YEGETRLITHWLWKEWPDWQVPESSEVMLKILRKIR
|.|....| ||||... | .|||||.|.| |....|.|.. . ..... . ..| .. ...|.| .||. .. ||| ||.| . .|..|...|
mvweqgvtvivmLteleelgrekcaqYwpl..getltygdftvtllseeelagitlrtlevedlgdsesrtvthfhytgWpdhgvppspdllldfleavr
AR----STPPVIHCSAGVGRSGTLMAVEIALQSIHTHFtLPDIKQIVSHLRVtGRAASVQTLQQYMLIWKVLLDFGV
. ..| ..||||||||.||. |....|. .... .|....| .|| |. .|||..||. . ..||..
ealedpggpvlVHCsaGvgRtGtfiaaylmleqlekeg.gvdveeavkelre.qRpgavqtpeqyrflydalleylk
|
|||||||||
subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 253-521 | 1.4e-43 | 144.2 | In-house | 14-283 (297) | alignment | ||
Range on Protein: 253-521
Range on HMM: 14-283/297.0
DFAMSSQK-MTLDDFKQEFSNLPGDpPSDLCTVFNHPVNNKKNRYSNIPCLDISRVQLKFKmPNKNSTDYIHANYIRSpfLKRGYILTQGPKKETRADFW
||| || . | |..|| || || .. || .|.||.|| | |||.|. .. . ||. | .... | .| || |.|.| ||||
dfatlvqknrhtdvfseeflclpea.niqpqtvaekkvnfeksRYkniLPydssRvkLaiv.nddpdsDyvnasfvkg..nkhrlittqmPmkatvadfW
RMIWQENTTAIVMLCQFLETNReKCAEYFPRNAHCClqFDKFSVNYEDSTVNKSLVTTRLNLSYEG--ETRLITHWLWKEWPDWQVPE--SSEVMLKILR
.|...|....|||| . |... ||| |.. .. | . || . . . . |... . .|.. . . |||| .|.. | . .||..
amvldeqvstivmlnddnerdk.kcaryWsdkgvtt..fGdvsvvllsvsereGfikrelevtkgkakarrvvkqyqfveWPdkaverkdsassllklis
KIRA-----RSTPPVIHCSAGVGRSGTLMAVEIALQSIHTHfTLPDIKQIVSHLRvTGRAASVQTLQQYMLIWKVLLDF
.| ..| ..||.||||| | |.... . .. . || ..|..|| | ||| .|| ......|..
evrkdfsqnaegPllvhclaGvGrtgvlltidsvvaeakre.kevdifglvkklr.qerpylvqtkeqykfvyvavlea
|
|||||||||
subfamily_Cele-PTP-13_pd | Subfamily Cele-PTP-13 | 254-534 | 7.2e-207 | 679.3 | In-house | 1-281 (281) | alignment | ||
Range on Protein: 254-534
Range on HMM: 1-281/281.0
FAMSSQKMTLDDFKQEFSNLPGDPPSDLCTVFNHPVNNKKNRYSNIPCLDISRVQLKFKMPNKNSTDYIHANYIRSPFLKRGYILTQGPKKETRADFWRM
|||||||||||||||||||||||||||||||||.|||||||||.|||||||||||||.||||||||||||||||||||||||||||||||||||||||||
famssqkmtlddfkqefsnlpgdppsdlctvfnqpvnnkknrylnipcldisrvqlkvkmpnknstdyihanyirspflkrgyiltqgpkketradfwrm
IWQENTTAIVMLCQFLETNREKCAEYFPRNAHCCLQFDKFSVNYEDSTVNKSLVTTRLNLSYEGETRLITHWLWKEWPDWQVPESSEVMLKILRKIRARS
|||||||||||||||||||||||||||||||||||||||.||.|||||||||||||||||||||||||||||||||||||||||||||||||||||||||
iwqenttaivmlcqfletnrekcaeyfprnahcclqfdklsvsyedstvnkslvttrlnlsyegetrlithwlwkewpdwqvpessevmlkilrkirars
TPPVIHCSAGVGRSGTLMAVEIALQSIHTHFTLPDIKQIVSHLRVTGRAASVQTLQQYMLIWKVLLDFGVAYKQITEELAE
||||||||||||||||||||||||||||.||||||||||||||||||||||||||||||||||||||||||||||||||||
tppvihcsagvgrsgtlmaveialqsihshftlpdikqivshlrvtgraasvqtlqqymliwkvlldfgvaykqiteelae
|
|||||||||
subfamily_Cele-PTP-10_pd | Subfamily Cele-PTP-10 | 254-523 | 5.6e-49 | 161.4 | In-house | 14-290 (305) | alignment | ||
Range on Protein: 254-523
Range on HMM: 14-290/305.0
FAMSSQKMTLDDFKQEFSNLPGDPPSDLCT-VFN----HPVNNKKNRYSNIPCLDISRVQLKfkMPNknSTDYIHANYIRSPFL-KRGYILTQGPKKETR
| . . . .| ...|| .| |. .|| .. ||||...|| | | |.|. |. .|||||||. |.. .. .| .||| .|
fvlraldvgvdklreefrglakytrpdmtqvafnanqsadiaitknryqdvpcqdqsavkld..kps..psdyihanyvgcpmipekrficaqgpldqti
ADFWRMIWQENTTAIVMLCQFLETNREKCAEYFPRNAHCCLQFDKFSVNyEDSTV------NKSLVTTRLNLSYEGETR-LITHWLWKEWPDWQVPESSE
.|| |. |.. |||||. .|. . |||.|.| |.. | |. . . . | |||.| |. . . | | |||| ||
defwwmviqnkveqivmlcktvelgklkcaqywpaaqgeklelksgivv.envsgskpmerdaeiqitllnltysgdqkmsvrhlqwtewpdrgvppckl
VMLKILRKIRARSTPPVIHCSAGVGRSGTLMAVEIALQSIHTHFTLPDIKQIVSHLRvTGRAASVQTLQQYMLIWKVLLDFGV
|..| || | |.|||||.||.||..|.| |. | | . ..| || || |.|. ||. | .|.|.. .
tslellsairgskvpivvhcsagigrtgtivaieyilekiaenkpcppmpelvkalr.dqrafsiqndvqylfihrvmlnyfl
|
|||||||||
0050432 | (Phosphotyrosine protein) phosphatases II | 255-525 | 1.1e-82 | 273.1 | In-house | 32-302 (308) | alignment | ||
Range on Protein: 255-525
Range on HMM: 32-302/308.0
AM-SSQKMTLDDFKQEFSNLPGDPPSDLCTVFNHPVNNKKNRYSNIPCLDISRVQLkfkmpnKNSTDYIHANYIRSP--FLKRGYILTQGPKKETRADFW
. ... | ...|| |. .|. ..|...| | .||||..|...| ||| | ....|||.|.|.. . |.| .|.||||...| .|||
lkllekaldlglleeefeellsvkplleysvallpenkdkNrykdilpydhsRVkl......degsdYInAsyvdgyssklprkfIatqgPlpntvedFw
RMIWQENTTAIVMLCQFLETNREKCAEYFPRNAH-CCLQFDKFSVNYEDSTVNKSLVTTRLNLSY--EGETRLITHWLWKEWPDWQVPESSEVMLKILRK
||.|..|.. ||||... | .|||||.|.| . . .|...||.|.. . .|... ... | |.. .||.| .||. .. ||| .||.| | .|..|..
rmvweqnvrvIvmLtklvengrekcaqYwplelgggsleygkftvtllseevlddytvrtleltnlgdgesrtvthfhytnWpdhgvPpspeilldflel
IRAR--STPPVIHCSAGVGRSGTLMAVEIALQSIHTHfTLPDIKQIVSHLRVTgRAASVQTLQQYMLIWKVLLDFGVAY
.| . . | |.||||||||.||. |....|. .... .|. ..| .|| |. .|||..||... ..||.. .
vrkslpggpivVHCsaGvGRtGtfialdllleqleke.ggvdvfeavkklReq.Rpgmvqtpeqylflyralleylklk
|
|||||||||
subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 255-524 | 5.3e-59 | 194.8 | In-house | 14-285 (319) | alignment | ||
Range on Protein: 255-524
Range on HMM: 14-285/319.0
AMSSQKMTLDDFKQEFSNLPGDPPSDLcTVFNHPVNNKKNRYSNIPCLDISRVQLKfKMPNKNSTDYIHANYIRSPFLKRGYILTQGPKKETRADFWRMI
. .. . ...|| .| . . .. . ... |.|||||.|| | .||.|. ........||| |..| . .. .| ||.|...| |||||.
lkalastgetllekefkllkeavndtf.dsaskeenkkknryqnilaydrtrvvls.eldgvegsdyinasfidgyqerekfiatqaPlentiedfWrmv
WQENTTAIVMLCQFLETNREKCAEYFPRNahCCLQFDKFSVNYEDSTVNKSLVTTRLNLS---YEGETRLITHWLWKEWPDWQVPESSEVMLKILRKIRA
|.|.. .|||.. | . |. .|.|.. . .. .. |. |. . .. .|.| | ||| ..|. ..|||| .|||.. .|..|..||
Weeessivvmltklveklkvklkkywpee..nfeeyGrlivtleeeeeledyiirklklnkkssevetRevkhfqyteWpdhdvPekatslldllkrirk
-----RSTPPVIHCSAGVGRSGTLMAVEIALQSIHTHFTLpDIKQIVSHLRvTGRAASVQTLQQYMLIWKVLLDFGVA
| | |.|||||||| || ......|. .. .| |. ..||.|| | | ||. .|| .|...||.. |
srektqsgPivvhCsaGvGRtGtfivldamlervkeegvl.DvfstvsrlR.tqRnimvqrpeqYkfiyealleavea
|
|||||||||
subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 257-521 | 5.2e-61 | 201.2 | In-house | 14-278 (288) | alignment | ||
Range on Protein: 257-521
Range on HMM: 14-278/288.0
SSQKMTLDDFKQEFSNLPGDPPSDLCTVFNHPVNNKKNRYSNIPCLDISRVQLKfKMPNKNSTDYIHANYIRSPFLKRGYILTQGPKKETRADFWRMIWQ
.... ..|..|. .|. .. |. ...||.||||| || .| ||.|| |.......||| |.|| . |. || |||| .| |||.....
kksarnrtgfseeynsLaalektksvtagrlavnakknRyrnilpyDekrvklk.kleeeagaDYinasyidgekkkkkyiatqgPladtvndfWelvye
ENTTAIVMLCQFLETNREKCAEYFPRNAHcCLQFDKFSVNYEDSTVNKSLVTTRLNLSYEGETRLITHWLWKEWPDWQVPESSEVMLKILRKIRARS---
..|. |||| ...| ...|| ||.| . . .. .. | .| .. |. .| | ... . ||.. .. ||| .||||.. .|..||.. .
nktstivmltelveggktkCeeYWPdadk.pknyGsvtvtlveskeledfvlrklllekkkteleitqyqylaWpdhgvPeskapllellrqvkvanqad
-TPPVIHCSAGVGRSGTLMAVEIALQSIHTHFTLpDIKQIVSHLRVTgRAASVQTLQQYMLIWKVLLDF
| ..||||||||.|| .|.. ... .... .. |. .|..|| || ||||.||. |..|||.
tgpiivhCsaGvGrtgtFialdalidaveeedyi.DvagtvaklRkq.RallvqtlkqYefiyevllsl
|
|||||||||
subfamily_Ptp69D_pd | Subfamily Ptp69D | 257-541 | 1.6e-53 | 176.9 | In-house | 15-303 (307) | alignment | ||
Range on Protein: 257-541
Range on HMM: 15-303/307.0
SSQKMTLDDFKQEFSNLPGDPPSDLCTVFNHPVNNKKNRYSNIPCLDISRVQLKfKMPNKNSTDYIHANYIRSPFLKRGYILTQGPKKETRADFWRMIWQ
|... | ...|. .|. . ..| .. |. |||| .| | ||.|| |.. |...||| |..|.. |. .| |.| .| ||||||..
srkrdtdfglakeyekLeareidkstkvsekkenalknRyedikafDktRvkLk.kingkedsdYinasfikgykekkkfiaaqdPveatigDfWRmiae
ENTTAIVMLCQFLETNREKCAEYFPRNahCCLQFDKFSVNYEDSTVNKSLVTTRLNLSYEG-------ETRLITHWLWKEWPDWQVPESSEVMLKILRKI
. | |||| . |.||.||| |.| . |... |.. .. . . |..| . ..| .. . ...|.| .|||... .||.....
qevtlivmlsnlteknrkkcakYWpie..devqygdilvklvseekhsdyiiReldvskkkeesgevedsrkvvqyhytgWkDskvPevargllklieqv
----RARSTPPVIHCSAGVGRSGTLMAVEIALQSIHTHFTLpDIKQIVSHLRVTgRAASVQTLQQYMLIWKVLLDFGVayKQITEELAEKFNSTYR
. .| |.||||||||||...|... || ... .. || ..| .|| | || |.||. ... |||. . |.| ........
relyklnrsPivvhCsaGvgrsgifvaldsllqqlkaedkv.difetvkdLrsq.RnllvqsleqYvflyralldyss..ygdtdedvddledaie
|
|||||||||
subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 257-521 | 1.6e-53 | 176.9 | In-house | 15-282 (305) | alignment | ||
Range on Protein: 257-521
Range on HMM: 15-282/305.0
SSQKMTLDDFKQEFSNLPGDppSDLCTVFNHPVNNKKNRYSNIPCLDISRVQLKFKMPNKnSTDYIHANYIRSPFLKRGYILTQGPKKETRADFWRMIWQ
...... ....... .|. . .. . | .. .|..|||...| || .|..|. | .. .||| |.|. . | ||..||| |.| |||||.|..
earvysdkgleaqykslyee..eesidvgkkeankaknrlkeitlldddriiltekesld.dsdyinasyvdgykrkkkyivaqgPlkntvadfWrlive
ENTTAIVMLCQFLETNREKCAEYFPRNAHCCLQFDKFSVNYEDSTVNKSLVTTRLNLSY---EGETRLITHWLWKEWPDWQVPESSEVMLKILRKIRARS
| .. ||||.. | ...|| |.| . .|..|||. .... . ... .|..| . |.| .... .||| ||... .|....... .
ekvstivmltklveggkdkCrqYWpesktekkefgefsvelksektasdyieRklkisiededkesrtvlqyqltdWPdhGvpqfatsllslikrvqkdq
T-----PPVIHCSAGVGRSGTLMAVEIALQSIHTHFTLpDIKQIVSHLRVTgRAASVQTLQQYMLIWKVLLDF
| ..||||||||.|. .||.|||. ... .. |. ... .|| . | ||||.||. .. .| .
kkdkgvpllVhCsagvgRtGvfiavdialerlkkEevv.dvfevlkqlRsk.rmkmvqtldqYvflhdaldel
|
|||||||||
subfamily_Cele-PTP-6_pd | Subfamily Cele-PTP-6 | 257-544 | 3.1e-53 | 175.8 | In-house | 9-302 (307) | alignment | ||
Range on Protein: 257-544
Range on HMM: 9-302/307.0
SSQKMTLDDFKQEFSNLPGDPPSDLcTVFNHPVNNKKNRYSNIPCLDISRVQLKFKmpnKNSTDYIHANYIRSPFLKRGYILTQGPKKETRADFWRMIWQ
. .. .. ...||..| | . || |..||||....| | .|. .||. ..|||||||. . .| .|||...|. .|| |. |
rtldkgvqalvdefrvlakktpegv.tveafsantdknryqdvkcqdkgrivvkfd...glasdyihanylgiaikpkkficaqgplentqysfwamaiq
ENTTAIVMLCQFLETNREKCAEYFPRNAHCCLQFDK----FSVNYED----STVNKSLVTTRLNLSYEGETRLITHWLWKEWPDWQVPESSEVMLKILRK
|. ...|||. .|. . || .|.| . | | . ||. . .. . | |.. . ...| |.|. |..||| ||. . .|
ekvesvimlckvielakikceqywpleegqklvfgeapntisvanlgakklapdedlinvttlkvdwaqksrtiqhlqwenwpdrgvpqinltainllea
IRARSTPPVIHCSAGVGRSGTLMAVEIALQSIHTHFTLPDIKQIVSHLRVTgRAASVQTLQQYMLIWKVLLDFGV-AYKQITEEL--AEKFNSTYRRSL
.| | |.|||||||||||..|. . . . . |.|..| || | ..|| ||. . .|||.. . ||. ||| ..... | . |
vrydtnpvvvhcsaGvGrsGtivaislvqdkmiaGinckdmkklveelrsq.rhyaiqteaqylylhrvlleyflelyketyeellltknyeekyakwl
|
|||||||||
subfamily_PTPN6_pd | Subfamily PTPN6 | 257-523 | 4e-52 | 172.1 | In-house | 19-298 (306) | alignment | ||
Range on Protein: 257-523
Range on HMM: 19-298/306.0
SSQKMTLDDFKQEFSNLPGDPPSDLCT--VFNHPVNNKKNRYSNIPCLDISRVQLKfkMPNKNSTDYIHANYIR--SPFLKRGYILTQGPKKETRADFWR
...... .|..|| .| . ..| . ..| |..|||| || | .|| || |. .||| ||||. .. .. || ||| ..| .||||
eeeslekagfeeefeelqqeeakkllsrkegakpenkeknryknilPfDhtrvilk..epsvpgsdyinanyikkevkgsdksyiatqgclettvsdFWr
MIWQENTTAIVMLCQFLETNREKCAEYFPRNAHCCLqFDKFSVNYEDSTVNKSLVTTRLNLS---YEGETRLITHWLWKEWPDWQVPESSEVMLKILRKI
|.||||.. |||. . .| ..|||| |.| . . . | ||. ... ... . .|..| ..|.| . .. .|.||| ||.. ...|. |...
mvwqensrvivmttkevErgkekCarYWPdeeekee.yGkisvtnvseksladYilRelsvskkkkkkeerevfqyhfksWPdhgvpkdpgavLdfledv
RARS--------TPPVIHCSAGVGRSGTLMAVEIALQSIHTHF--TLPDIKQIVSHLRvTGRAASVQTLQQYMLIWKVLLDFGV
.... | |.|||||.|| ||.. ..| |. |... . ||...| .| . | ||| ||| ...|.. .
nrkqeeleeaeagpivvhCsaGiGRtGtfiviDillkliekkgldadidiqklvksvr.eqrsglvqteqqykfvykaikkyie
|
|||||||||
subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 258-520 | 8.2e-50 | 164.3 | In-house | 14-274 (515) | alignment | ||
Range on Protein: 258-520
Range on HMM: 14-274/515.0
SQKMTLddFKQEFSNLPGdPPSDLCTVFNHPVNNKKNRYSNIPCLDISRVQLKFkMPNKNSTDYIHANYIRSPFLKRGYILTQGPKKETRADFWRMIWQE
... || | .|| .||| | || . .| ||||| || .| .||.|. . .. ||. | ||.| . || .|||.| . ||||...||
nrhttl..fseefhdlpg.pniypqtvaqeeinfkknryknilPydsvrvklev.indnPhsdyfnasyipsfdndkayiasqgPnkasvddfWrlvlqe
NTTAIVMLCQFLETNREKCAEYFPRNAHCCLQFDKFSVNYEDSTVNKSLVTTRLNLSYEGETRLITHWLWKEWPDWQVPESSEVMLKILRKIRARS----
|.|.|.|. . | .. ||..|.| ..| ...|. . .|.. . ..| .| . ..|||| ||. . .||......|
nvttiamvtklkegdkikcgkyWPdkpgdsvkfGsikvelvsleactggikrkltvlkgddsrtvtqfhfteWPdkGvpkhtssllklikevkadhgqyt
TPPVIHCSAGVGRSGTLMAVEIALQSIHTHFTLpDIKQIVSHLRVtGRAASVQTLQQYMLIWKVLLD
| .||||||||| | ..... . ..| .. |. ..| .| | ||| .|| .|. ..|.
hpliihcsaGvGrtGvvisidsvvahakttrmv.dvfnfvtnirq.krpylvqtqeqyafiygavle
|
|||||||||
0036941 | (Phosphotyrosine protein) phosphatases II | 259-527 | 6.2e-80 | 264.0 | In-house | 8-282 (297) | alignment | ||
Range on Protein: 259-527
Range on HMM: 8-282/297.0
QKMTLDDFKQEFSNLPGDPPSDLCTVFNHPVNNKKNRYSNIPCLDISRVQLkfkmpNKNSTDYIHANYIRSPFLKRGYILTQGPKKETRADFWRMIWQEN
... | ...||. |. .. ..|.. | | .||||..|...| .||.| .....|||.|.|. . ||| .|.||||...| .|||||.|..|
kllflalllkefeellpllllgslsvallpenleknRykdilpydhtRVkl.....ddegsdYinAsyvdgydlkrkfIatqgPlpntvedFWrmvweqn
TTAIVMLCQFLETNREKCAEYFPRNAHCCLQFDKFSVNYEDSTV--NKSLVTTRLNLSY--EGETRLITHWLWKEWPDWQVPESSEVMLKILRKIRA---
.| ||||... | .|||||.|.| . |....|.|.. . .| ... ... | ... .||.| .||. .. ||| |||| . .|......|
vtvIvmltelvelgrekcaqywpleegesltygdftvtllsvevvllddytlrtlevtdtgngesrtvthfhytgwpdhgvpespaslldfielvrkvlk
---RSTPPVIHCSAGVGRSGTLMAVEIALQSIHT--HFTLPDIKQIVSHLRVTgRAASVQTLQQYMLIWKVLLDFGVAYKQ
...| ..|||||||||||. |....|| ... . .||...| .|| |. .||||.||. . .||.. ...
llpsggpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReq.Rpgavqtleqyrflyeallellkkklt
|
|||||||||
0047943 | (Phosphotyrosine protein) phosphatases II | 259-520 | 1.3e-77 | 256.3 | In-house | 7-270 (273) | alignment | ||
Range on Protein: 259-520
Range on HMM: 7-270/273.0
QKMTLDDFKQEFSNLPGDPPSDLCTVFNHPVNNKKNRYSNIPCLDISRVQLkfkmpNKNSTDYIHANYIRSPFLKRGYILTQGPKKETRADFWRMIWQEN
.. |. ...|| |. .|. ..|...| | .||||..|...| ||| | . ...|||.|.|.. . ||| .|.||||...| .|||||.|..|
kllgltllleefelllslkplltysvallpenkdknrykdilpydhsrvkl.....gdggsdyinAsyvdgynlkrkfiatqgPlpntvedfwrmvweqn
TTAIVMLCQFLETNREKCAEYFPRNAHC-CLQFDKFSVNYEDSTVNKSLVTTRLNLSY--EGETRLITHWLWKEWPDWQVPESSEVMLKILRKIRA----
.. ||||... | .||||| |.| . |...||.|.. . ..... ... | |.. ||.| .||.....||| .||.| | .|......|
vrviVmLtelvelgrekcaqYwpleggelsltygkftvtllseetkddytvrtleltnlgtgesrtvthfhytgwpdhgvppslesllefielvrkalea
--RSTPPVIHCSAGVGRSGTLMAVEIALQSIHTHfTLPDIKQIVSHLRVTgRAASVQTLQQYMLIWKVLLD
...| |.||||||||.||. |....|. .... .|....| .|| | .|||..||... ..||.
lpsngpvvVHCsaGvgRtgtfialdllldqleke.ggvdvleavkllrsq.Rpgmvqtpeqyrflyealle
|
|||||||||
subfamily_Sponge-PTP9_pd | Subfamily Sponge-PTP9 | 259-519 | 4.9e-38 | 125.5 | In-house | 10-290 (301) | alignment | ||
Range on Protein: 259-519
Range on HMM: 10-290/301.0
QKMTLDDFKQEFSNLPGDpPSDLCTVFNHPVNNKKNRYSNIPCLDISRVQLKFKMP-NKNSTDYIHANYIRSPFLKRGYILTQGPKKETRADFWRMIWQE
.. ..|......| .. ||| . |.. ||. || .| |. || | .. ...|| |.|| . |. .| .||| |.| .||||.||||
aakhsnkfeeqykelkeg.edksctvglseenkalnrfknitvyddnriilkpkpnldlcqreyinasyidgysekkkfiaaqgpmkktlvdfWrliwqe
NTTAIVMLCQFLETNREKCAEYFPRNAHCCLQFDKFSVNYEDSTVNKSLVT-----------------TRLNLSYEGETRLITHWLWKEWPDWQVPESSE
...|||... |. ..|| .|.|. . .| .|.| ...| . | ... . . ... .. . .||. |
kpvsivmvtnlkegtkskceqywpnseaeseefgpftvtlvneqvyPdfvirqlnvkiqdgsnngyierkfkvksdksswdvlqlqvtdWpqdGvvrepr
VMLK-----ILRKIRARSTPPVIHCSAGVGRSGTLMAVEIALQSIHTHFtLPDIKQIVSHLRVTgRAASVQTLQQYMLIWKVLL
.|. | |. . | |.|||..|.|||. ..|.|.| |. |.. .| . . |.||.||. |..|.
tvLqviddvihrqqkigggpvvVHCSdtVsrsGvYcsvsiglEQckaeg.VVdvfqvtkavrrs.kpgaVtTLeqytsiydvid
|
|||||||||
subfamily_Cele-PTP-4_pd | Subfamily Cele-PTP-4 | 259-523 | 6.1e-30 | 98.7 | In-house | 21-286 (302) | alignment | ||
Range on Protein: 259-523
Range on HMM: 21-286/302.0
QKMTLDDFKQEFSNLPGD-PPSDLCTVFNHpvNNKKNRYSNIPCLDISRVQLKfkmpnKNSTDYIHANYIRSPFLKRGYILTQGPKKETR---ADFWRMI
.... |.|| .. . . |..| . | |||. ..|.|| .|.|. .. .|..| . | |.| ||.| ||... ..||||.
ksldtaevkkefkkidtmkvdlekCkafkk..nlkknqsedvpildsnlvkle.....aepdsyvnaskvevPeltrsiilaQlpkvdsedsveeFWrmv
WQENTTAIVMLCQFLETNReKCAEYFPRNAHCCLQFDKFSVNYEDstVNKSLVTTrLNLSYE------GETRLITHWLWKEWPDWQVPESSEVMLKILRK
.||. . .|.| . | .. |.||... ....|. || |.|. .. ....| .. |.. . . |.. .||.. . | |
fqekivsvvilvgeeelkk.tlselfpkksgdykeygkmfvNnrk..Vekaeeek.tryviEvlPegcsnsvlanvyvltnWkqkkvpvkyaeliktaak
I----RARSTPPVIHCSAGVGRSGTLMAVEIALQSIHTHfTLPDIKQIVSHLRvTGRAASVQTLQQYMLIWKVLLDFGV
. . . || |.|| |..... .|....... | ||.|| .| . |...|..|.||. .. .|| ..
vfakkikadentvivSknGaGRagafltlavaveklqkg.kepnikeivksiR.sqRpravdslkQyvslyialllyik
|
|||||||||
0051299 | (Phosphotyrosine protein) phosphatases II | 260-521 | 2.9e-78 | 258.6 | In-house | 19-285 (288) | alignment | ||
Range on Protein: 260-521
Range on HMM: 19-285/288.0
KMTLDDFKQEFSNLPGDPPSDLCTVFNHPVNNKKNRYSNIPCLDISRVQLKfKMPNKNSTDYIHANYIRSPFLKRGYILTQGPKKETRADFWRMIWQENT
. | ...|| |. |. ......| | .|||||.|...| |||.|. ... ...|||.|.||. . ||| .|.||||...| .|||||.|..|.
angltglleefeellsllpdltlsaallpenleknRysdilpydhsRVkLs.vldgvegsdYinAsyidgynlkrkfIatqgPlpntvedFWrmvweqnv
TAIVMLCQFLETNREKCAEYFPRnaHCCLQFDKFSVNYEDSTVNKSLVTTRLNLS------YEGETRLITHWLWKEWPDWQVPESSEVMLKILRKIRAR-
. ||||... | .||||| |.| . .|......|.. . .|... ... | .. ..||.| .||. .. ||| .||.| | .|..||..|
rvIvmltklvelgrekcaqYwpl..ggsltygditvtllseevlddytvrtlevtnldlldgdgesrtvthfhytnwpdhgvpdspellldflrlvrkal
---STPPVIHCSAGVGRSGTLMAVEIALQSIHTHfTLPDIKQIVSHLRvTGRAASVQTLQQYMLIWKVLLDF
. | |.||||||||.||. |....|. .... .|. ..| .|| . | .|||..||... ..||..
asgggpvvVHCsaGvgRtgtfialdllleqleke.ggvdvleavkrlr.eqRpgmvqtpeqyrfvyealley
|
|||||||||
subfamily_PTPN13_pd | Subfamily PTPN13 | 260-520 | 6.6e-51 | 168.2 | In-house | 7-267 (273) | alignment | ||
Range on Protein: 260-520
Range on HMM: 7-267/273.0
KMTLDDFKQEFSNLPGDPPSDLCTVFNHPVNNKKNRYSNIPCLDISRVQLKFKMPnknstdYIHANYIRSPFLKR--GYILTQGPKKETRADFWRMIWQE
|. .. ..|| .| | | |.| .. |..|||| |. | .||.|. . . || |..|. | | ||..||| || .|||.|.|.
kldqqqPaeefkelrelkpldtcevgkkkenkdknryrnvlPydetrvklgdegg......yinaslikvpvgkdeyeyiacqGPlPetvkdfwqmvweq
NTTAIVMLCQFLETNREKCAEYFPRNAHCCLQFDK-FSVNYEDSTVNKSLVTTRLNLS--YEGETRLITHWLWKEWPDWQVPESSEVMLKILRKIRAR--
... |.|. . |... || |.| ... |. . |. .. . ...| .|... ||.| ..| . .||| .|| |.. .|......|
kaeviamvtlekekgkvkchrywPesknkklkvsnrlevellkvqkldgfvvralavkdsesgesrevahlnfvkwPdhgvPssaaellqfvaevrrlqt
-STPPVIHCSAGVGRSGTLMAVEIALQSIHTHFTLpDIKQIVSHLRVTgRAASVQTLQQYMLIWKVLLD
..| |.|||||.||||||......|. |. . |.|.|| .|| | . ||| .||....|..|.
dagPivvhcsaGiGrsGtlitidvvlglierdkef.dvkeivrklreq.rqgvvqtkdqyifvykaile
|
|||||||||
subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 260-523 | 1.6e-46 | 153.7 | In-house | 20-280 (315) | alignment | ||
Range on Protein: 260-523
Range on HMM: 20-280/315.0
KMTLDDFKQEFSNLPGDPPSDLCtVFNHPVNNKKNRYSNIPCLDISRVQLKFkMPNKNSTDYIHANYIRSPFLKRGYILTQGPKKETRADFWRMIWQENT
| . |||.. ..|| | | .. | .|||| || | ||||| . . |.. .||. ||.| || || .|||. .. ||||....|.
astkngfkqdyesipggqlhpld.vakkienkqknryiniiaydksrvqlpl.lendphsdyvnanfidGynkkrryiaaqgpnvasvkdfwrlvfeedi
TAIVMLCQFLETNREKCAEYFPRNahcCLQFDKFSVNYEDSTVNKSLVTTRLNLSYEGETRLITHWLWKEWPDWQVPESSEVMLKILRKIRARS----TP
. |||| . | ...|. .|.| . . . |..| . ||. . | .. . | . . . ||| .||... .... |... ..
gkivmltnlvegekrkaekywpdk...kviyGkitvtrkseevnteytvrtlsvvfgdnirevvqlhytswpdmgvpkytiplmnlirtvkqhhtnsvga
PVIHCSAGVGRSGTLMAVEIALQSIHTHfTLPDIKQIVSHLRVTgRAASVQTLQQYMLIWKVLLDFGV
|.||||||||.||..... |. ... . |. ... .| | ||...|| .|...||. |
ivvhcsaGvGrtGtfitldavldqaeae.naidvynfitgvrqn.rikmvqvaeqyqfiydalletfv
|
|||||||||
0043336 | (Phosphotyrosine protein) phosphatases II | 261-520 | 5.3e-75 | 247.7 | In-house | 17-275 (278) | alignment | ||
Range on Protein: 261-520
Range on HMM: 17-275/278.0
MTLDDFKQEFSNLPGDPPsDLCTVFNHPVNNKKNRYSNIPCLDISRVQLKFkMPNKNSTDYIHANYIRSPFLKRGYILTQGPKKETRADFWRMIWQENTT
...|| .|. .. | ......| | .||||..|...| |||.|. ... ...|||.|.|. . .|..|.|||| .|| .|||||.|....|
nlktllllefeellsfkl.dtysiallpenkdknrykdilpydhsrvklsl.lggdldsdYinAsyvdgynvprkfiatqgPlpetvedFwrmvwelgvt
AIVMLCQFLETNREKCAEYFPrnaHCCLQFDKFSVNYEDSTVNKSLVTTRLNLS--YEGETRLITHWLWKEWPDWQVPESSEVMLKILRKIRA----RST
||||... | .|.|||.|.| |....|.|.. . .... ... |... ..||.| .||. .. ||| .|||| . .|..|...| ...
tivmLtelvelgrvkcaqYwp...ggsltygdftvtllkeehlddytvrtlevtnlgdgesrtvthyhylgwpdhgvpeslsllldflkavrealedsng
PPVIHCSAGVGRSGTLMAVEIALQSIHTHFtLPDIKQIVSHLRVTgRAASVQTLQQYMLIWKVLLD
| ..||||||||.||..|....|. .... .|. ..|..|| |. .|||..||. . ..||.
pvlVHCsaGvgRTGtfialyllleqlekeg.gvdleeavkelreq.Rpgavqtpsqyrflyealle
|
|||||||||
subfamily_Cele-PTP-8_pd | Subfamily Cele-PTP-8 | 261-523 | 3.2e-46 | 152.7 | In-house | 16-272 (288) | alignment | ||
Range on Protein: 261-523
Range on HMM: 16-272/288.0
MTLDDFKQEFSNLPGDPPSDLCTVFNHpvNNKKNRYSNIPCLDISRVQLKfkmpnKNSTDYIHANYIRSPFLKRGYILTQGPKKETRADFWRMIWQENTT
.... |.|. . | . . | ..| | ..|| |.|. ||.||.|. .. ||.|| . | || | .| | . | .|.|. ...
iaveglkkeyrdspneasidiidsfia..nptrdryenlprcditrvkls.....ddpdfyiaanvvssakykrrlicaqaPlngtieelWkmllesdve
AIVMLCQFLETNREKCAEYFPRNAHCCLQFDKFS--VNYEDSTVNKSLVTTRLNLSYEGETRL-ITHWLWKEWPDWQVPESSEVMLKILRKIRARSTPPV
|||||..|| .|| ||||| . .. .. | . . ..| .. . |. | |||.. . . ..||.| |||. |..| ... | |
yivmlcellekGkeksaeyfPsklGekarigrlctvvkkkradidklvkvsllriskegeekvivkilhlleWdddgvPenylsplrllevlkslqkPiv
IHCSAGVGRSGTLMAVEIALQSIHTHFTLpDIKQIVSHLRVTgRAASVQTLQQYMLIWKVLLDFGV
.|.||||||.|||. . |||.|. . | |......|| | ..|| .||. .....|. .
vhssaGvGrtgtlililialeslrlddfl.girsllaklree.rfkaiqtemqylyvhrcvleell
|
|||||||||
subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 262-520 | 1.2e-59 | 196.7 | In-house | 13-274 (281) | alignment | ||
Range on Protein: 262-520
Range on HMM: 13-274/281.0
TLDDFKQEFSNLPGDPPSDLCTVFNHPVNNKKNRYSNIPCLDISRVQLKfKMPNKNSTDYIHANYIRSPFLKRGYILTQGPKKETRADFWRMIWQENTTA
|..|...| .. | ... | .||||||| | .||... . ....|||| ||.. . ...|| |||| .. ..||.|.|... .|
dnaGfieeyeklaaigvdntataskadenvlknrYsnivaYDatrvkvt.pneenkntDYinanfvpgykgekeyiatqgPvPaslvafWqmvweqkvsa
IVMLCQFLETNREKCAEYFPRNAHcCLQFDKFSVNYEDSTVNKSLVTTRLNL-SYEGETRLITHWLWKEWPDWQVPESSEVMLKILRKI---RAR--STP
|||. . .|... || |.| ... |.. .. |. . .. ... .. ...| .|||| ... .. ||| ||.... .|. ... . . .|
ivmvtreieagklkChrYWPddns.elkygdvtvkstaeeekatyierkfkleresgetreveqlaytaWPdhGvPattkellefrkevlkltekktkap
PVIHCSAGVGRSGTLMAVEIALQSIHTHFTLPDIKQIVSHLRVTgRAASVQTLQQYMLIWKVLLD
||||||||||.|| .|.. ........ . |.|..| .|| . | |||. || ..|..||
lvihCsaGvGrtGtyialDrlvkaveaeleeldvkavvaelrke.rnlmvqtvvqyefvykavld
|
|||||||||
subfamily_PTPN9_pd | Subfamily PTPN9 | 263-527 | 2.1e-61 | 202.6 | In-house | 15-295 (297) | alignment | ||
Range on Protein: 263-527
Range on HMM: 15-295/297.0
LDDFKQEFSNLPGDPPSDLCTVFNHPVNNKKNRYSNIPCLDISRVQLKfKMPNKNSTDYIHANYIRSPFLKRGYILTQGPKKETRADFWRMIWQENTTAI
..|. .. |.. .......| .||||... |.| .||.|. |..... .|||.||.. |...| |||| |.| |||||.|.... |
krGlskeyaeirnepveGtflasklranleknrytdvlcydetrvvla.kvdedeasdyinanfvdGykqkkafiatqGplkktvsdfWrmvWeqevlvi
VMLCQFLETNREKCAEYFPRNAHCCLQFDKFSVNYEDSTVNKSLVTTRLNLS--YEGETRLITHWLWKEWPDWQVPESSEVMLKILRKIRAR--------
|| ...|. | ||..|.| . . . .| ..||. . ... ... |... ..|.| .||. |||. ||.|.. .|..|.|.| .
vmttrvvergrlkcgqyWpleeessaefgdlsvsnveveeeedykvrvleiknvkteesrkvthfqflsWPdyGvPssaaslldvlekvrekqalavkel
--------STPP-VIHCSAGVGRSGTLMAVEIALQSIHTHFTLpDIKQIVSHLRvTGRAASVQTLQQYMLIWKVLLDFGVAYKQ
| || |.|||||.||.||.....|.|. ... |. |. . |..|| | || |.|| .||.. .. .|.. . |.
gdewkghpsgPPivvhcsaGiGrtGtfitldiclsrleevgtv.dvvetvkllr.tqrafsiqtpeqyefcylavleyalelka
|
|||||||||
subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 263-521 | 1.5e-42 | 140.9 | In-house | 22-287 (325) | alignment | ||
Range on Protein: 263-521
Range on HMM: 22-287/325.0
LDDFKQEFSNLPGDPPSDlCTVFNHPVNNKKNRYSNIPCLDISRVQLKFKMpNKNSTDYIHANYIRSPFLKRGYILTQGPKKETRADFWRMI--WQentT
| | .|| || | . .| .| | .|||. |. || ||| |. | .. |.||| |.|.|. | .. .| |. .| |.||.. |. .
qdgfahefgllpsddgia.kkvamkpenkaknrfknvvaldksrvvletkk.ddpssdyinasylrddkkkdvflaaqaPltatindlWrlvldWr...c
AIVMLCQFLETNREKCAEYFPRNAHCCLQFDKFSVNYEDSTVNKSLVTTRLNL--SYEGETRLITHWLWKEWPDWQVPESSEVMLKILR-------KIRA
..|.. |... ..|| |.|.. .| . |. | .|.. .|||| . . .. |.| |.. .. ||. ...|
svvvvlneldlgkdrcavywpkemgksktfGglevklrtieeisdyvhrvldvkqvkkGetrsvkqfqlqswddmGvqkrpatlisilqlvkavservta
---RSTPPVIHCSAGVGRSGTLMAVEIALQSIHTHFTLpDIKQIVSHLRVtGRAASVQTLQQYMLIWKVLLDF
||| ..||||||||.|..... ||. . .. . || . | .|| | . |.| ||.||.. | ..
ntkastpilvhcsaGvGrtGvfislysalakvieesrv.difgfvkklrk.drpsmvetvdqyiliyealvea
|
|||||||||
0039614 | (Phosphotyrosine protein) phosphatases II | 264-521 | 5.4e-76 | 251.2 | In-house | 32-288 (297) | alignment | ||
Range on Protein: 264-521
Range on HMM: 32-288/297.0
DDFKQEFSNLPGDPPSdlCTVFNHPVNNKKNRYSNIPCLDISRVQLKFKMPNKNSTDYIHANYIRSPFL-KRGYILTQGPKKETRADFWRMIWQENTTAI
...|| .|. .|. ......|.| .||||..|...| |||.|| .. ...|||.|.|. . | .| .|.|||| .|| .|||||.|....|.|
tllllefeellslkpd..ysiallpenkdknrykdilpydhsrvklkpedgvdldsdYinAsyvdgydlltrkfIatqgPlpetvedFwrmvweqgvtvi
VMLCQFLETNReKCAEYFPRNAHcclQFDKFSVNYEDSTVNKSLVTTRLNLSYEGETRLITHWLWKEWPDWQVPESSEVMLKILRKIRA------RSTPP
|||... | .| |||.|.| . ....|.|.. . .... ... |.....||.| .||... ||| .||.|.|..|..|...| ...|
vmLtklvelgr.kcaqywpeegg...tygdftvtllkvehldgytvrtlevtnngesrtvthfqytgwpdhgvppslellleflelvrealaelpkggpv
VIHCSAGVGRSGTLMAVEIALQSIHTHfTLPDIKQIVSHLRvTGRAASVQTLQQYMLIWKVLLDF
..||||||||.||. | ..|. .... .|....|..|| | .|||..||. . ..||..
lVHCsaGvgRtGtfiaaylmleqleke.ggvdvleavkelr.eqRpgavqtpsqyrflydallel
|
|||||||||
0045098 | (Phosphotyrosine protein) phosphatases II | 264-522 | 1.7e-67 | 223.0 | In-house | 7-272 (278) | alignment | ||
Range on Protein: 264-522
Range on HMM: 7-272/278.0
DDFKQEFSNLPGDPPSDLCTVFNHPVNNKKNRYSNIPCLDISRVQlkfkmpnknstDYIHANYIRSPflKRGYILTQGPKKETRADFWRMIWQENTTAIV
|...|| .|. .. . .|... . | .||||..|...| ||| |||.|.||... .. .|.||||...| ||||||.|....|.||
ldlllefefllllgipseitpalylgnldknRykdilpydhsrVk...........dYINAsyidgy..pkkfIatqgPlpstvadfwrmlwelgitviv
MLCQFLETNREKCAEYFPRnaHCCLQFDKFSVNYEDSTVNKSLVTTRLNLS------YEGETRLITHWLWKEWPDWQVPESS--EVMLKILRKIRA----
||....| .|||||.|.| . .|....|.|.... .|.. ....|.. ...|.| .||. .. ||| ||... .|..|. ||.
mltelvelgrekcaqywpe..ggsltygdftvtllseevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkl
-------------RSTPPVIHCSAGVGRSGTLMAVEIALQSIhtHfTLPDIKQIVSHLRVTGRAASVQTLQQYMLIWKVLLDFG
...| ..||||||||.||| |. . |. . . |. ..|..|| . .||.|.||. . ..||..
laslllsslllldsggpvlVHCsaGvgRtGtlvaaylmlell..e.ggvdlleavkelrsqRpglavqnleqyrflyefllell
|
|||||||||
subfamily_PTPN5_RR_pd | Subfamily PTPN5_RR | 264-521 | 2.8e-58 | 192.2 | In-house | 5-267 (274) | alignment | ||
Range on Protein: 264-521
Range on HMM: 5-267/274.0
DDFKQEFSNLPGDPPSDLCTVFNHpvnNKKNRYSNIPCLDISRVQLKFKMPNKNSTDYIHANYIRSPFL-KRGYILTQGPKKETRADFWRMIWQENTTAI
|...|| .|| . . . .|| . ..|||| .| . ||| |. . .... ..|| ||||. . .. |. |||| .| |||||||.||... |
kdlekeflelPlnfdqeeldvfgs...qtknryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntvadfWrmiyqeevqvi
VMLCQFLETNREKCAEYFPRNAHC--CLQFDKFSVNYEDSTVNKSLVTTRLNLSYEGETRLITHWLWKEWPDWQVPESSEVMLKILRKIRA-------RS
||| .. |.|..|||.||| . .. ........ |. . .. ..| |.| ..| ..|... .||| ..|.. . .|....... .
vmltklkeaneqkCavyfPdaedyeiserygdveikvekiverndysvrklvlkylerersvkhywytdWPdhksPddantlldlvleveesreeenakl
TPPVIHCSAGVGRSGTLMAVEIALQSIHTHFTLpDIKQIVSHLRVTgRAASVQTLQQYMLIWKVLLDF
.| |.|||||.|| | .|..||.. .. . .. |. .||..||. | ||| .|| ||...| .
apvvvhCsaGiGrtGcfiaisiavrqlreeivv.dvlkivcnlrld.rGGmvqtseqyelihralcly
|
|||||||||
subfamily_PTPRA_pd | Subfamily PTPRA | 264-522 | 3.7e-58 | 192.0 | In-house | 32-295 (330) | alignment | ||
Range on Protein: 264-522
Range on HMM: 32-295/330.0
DDFKQEFSNLPGDPPSDLCTVFNHPVNNKKNRYSNIPCLDISRVQLKFKMpNKNSTDYIHANYIRSPFLKRGYILTQGPKKETRADFWRMIWQENTTAIV
|..|| .|| | . . .. |..|||. || | ||| | | ....||| | .| | .| .||||.|| |||||||. ....||
klfreefnalPagpiqatlelaskeenkeknrvvnilPydfsrvilsvke.GveesdyinasfidGykekdkfiaaqGPkeetvedfwrmiweqksativ
MLCQFLETNREKCAEYFPRNAhcCLQFDKFSVNYED------STVNKSLVTTRLNLSYEGETRLITHWLWKEWPDWQVPESSEVMLKILRKIRAR----S
|| .. | ..|||| |.| . .. . . |. || || | ||. . . | ..||.. . .. ||| || . |||.|.|... .
mltelkerkeekcaqywPdeG..lvtyGnirvevedetvlvdytvrkflvqqlpdatrekksrlvrqfhftswPdvGvPfepiGmlkllkkvkklnqqsa
TPPVIHCSAGVGRSGTLMAVEIALQSIHTHFTLpDIKQIVSHLRVTgRAASVQTLQQYMLIWKVLLDFG
| |.||||||||.||..... |. ... . |. ..|..|| |. |||..|| .|.||||..
gpivvhcsaGvGrtGtfivldavlervkaerkv.dvfefvkrlrlq.rpqmvqtdeqyefiykvlleyy
|
|||||||||
subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 264-520 | 1.1e-49 | 164.0 | In-house | 19-275 (315) | alignment | ||
Range on Protein: 264-520
Range on HMM: 19-275/315.0
DDFKQEFSNLPGdPPSDLCTVFNHPVNNKKNRYSNIPCLDISRVQLKFkMPNKNSTDYIHANYIRSPFLKRGYILTQGPKKETRADFWRMIWQENTTAIV
| .|| .||. |. .| ...| ||||| || || .||.|. . .. ||| | ||.| . || .|||.| . |||||..||..|.||
alfseefhdlpd.PdiyrqrvaretinfkknryknilPldsarvklev.iddsPdsdyinasyiksvdddkayiasqgPlkasvddfwrmvlqekvttiv
MLCQFLETNREKCAEYFPRNAHCCLQFDKFSVNYEDSTVNKSLVTTRLNLSYEGETRLITHWLWKEWPDWQVPESSEVMLKILRKIRARS----TPPVIH
|. . | .. ||. |.| . .| ...|. . . |. .| . |.| .| . ..|||| |.. . .||......| . ..|
mvtkkqegdkikcrqywPdrkadsvefGsikvellsleadtdgvarklvtrkseesrtvtqfqftewPdkGvdkqtssllklikevkadngkkefsllvh
CSAGVGRSGTLMAVEIALQSIHTHfTLPDIKQIVSHLRVtGRAASVQTLQQYMLIWKVLLD
|||||||.| ..... .. |. |. ..| || | ||| ..| .|. ..|.
csaGvGrtGvvisidevvaqikrt.rsvdvfnfvknlra.krpylvqteeeyafiydavle
|
|||||||||
subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 264-522 | 2.7e-46 | 153.4 | In-house | 34-294 (319) | alignment | ||
Range on Protein: 264-522
Range on HMM: 34-294/319.0
DDFKQEFSNLPGDPPSDL-CTVFNHPVNNKKNRYSNIPCLDISRVQLKFKMpNKNSTDYIHANYIRSPFLKRGYILTQGPKKETRADFWRMIWQENTTAI
.. || ... ... | | . | |||. || | ..|.|. .. .||| | .. | || .|||...| ||||||||. |...|
tklevefrracklgvnladqtfanldqnkdknriinilafdknvvklerli.GeefsdyinasfvtGyqrkdkyiaaqGPldntladfWrmiweyncsti
VMLCqfletnREKCAEYFPRNAHccLQFDKFSVNYEDSTVNKSLVTTRLNLSY---EGETRLITHWLWKEWPDWQVPESSEVMLKILRKIR------ARS
|.| ..||..|.| .. . ..| |. . . . | ..|| | . | || . .. ||| ||... ......|.|
vllt......kdkcsqywplkiv..ikeerfkvkvdsveetaeyvvrdielsedgkekdirkitqfhflGwpdvGvpdypsdlmrlvkkvrhltskenhr
TPPVIHCSAGVGRSGTLMAVEIALQSIHtHFTLPDIKQIVSHLRVtGRAASVQTLQQYMLIWKVLLD---FG
.. |.||||||||.|. ..... |. .. . |. ..| || | || | ||..|. ||. ||
anivvhcsaGvGrtGvyivldvlldrmk.eekqvdvynfvrdlrq.qrntlvqdlvqykfiysalleehlfg
|
|||||||||
subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 264-520 | 2.7e-33 | 110.0 | In-house | 10-275 (287) | alignment | ||
Range on Protein: 264-520
Range on HMM: 10-275/287.0
DDFKQEFSNLPGDPpSDLCTVFN---HPVNNKKNRYSNIPCLDISRVQLKFKmPnKNSTDYIHANYIRSPFLKRGYILTQGPKKETRADFWRMIWQENTT
|| ..|. .| | .| . . |||||... .| .|| | . . . .||| |||. | . .| .||| | ||||........
ddvdkevdalkeds.esstatfkaaeelaavkknryadvlPiddtrvllsae.g.elGsdyinanyvasytddeafiaaqgPiaatvrdfwravletrsa
AIVMLCQFLETNREKCAEYFPRNaHCCLQFDKFSVNYEDSTVNKSLVTT---RLNlSYEG-ETRLITHWLWKEWPDWQVPES----SEVMLKILRKIR--
..... . .| | || .|.| . . .. .|| | .. . .. || |. |.|.. . .||| .. . .|.. ..|
svitmtreveearlkcykywPer.evPmrvGGysvvlldydikePeygvralrli.dletrearvvkqldllswPdkvlaPtavglirfvldvkqhiela
---ARSTPPVIHCSAGVGRSGTLMAVEIALQSIHtHFTLPDIKQIVSHLRVTgRAASVQTLQQYMLIWKVLLD
. |.|.|...|.||||.|.|. . .. |. ..| .|| ||| ||. |. |... |
rdasevGPlvvhddvGiGrsGillatlvlvsrle.dlGrvdvaavvirlrey.raalvqavvqlrllyealvt
|
|||||||||
subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 265-532 | 3e-60 | 199.0 | In-house | 21-292 (318) | alignment | ||
Range on Protein: 265-532
Range on HMM: 21-292/318.0
DFKQEFSNLPGDPPSDLCTVFNHPVNNKKNRYSNIPCLDISRVQLKFKmPNKNSTDYIHANYIRSPFLKRGYILTQGPKKETRADFWRMIWQENTTAIVM
...|. .| .. . . ..|||..|||| || | .||.|. . .....||| |||| |. || .|.| || |||||.|. |.. |||
llseeyerlsrseetvtslkslepvnkaknryanilaydhtrvkLqml.egeegsDyinanyidGyrrkkayiaaqaPlpetieDfWrmvWeqnsavivm
LCQFLETNREKCAEYFPRNAhcCLQFDKFSVNYEDSTVNKSLVTTRLNLSYEG--ETRLITHWLWKEWPDWQVPESSEVMLKILRKIRARS-----TPPV
| | | ..|.. |.| . ...| |. .... ...| ..... .. |.| . . . .||| ||||. .|...|.... .| |
ltqeeergkakvhryWPskg..srsygklvvelkeevelsdyvlrefkvtrteeeesrqvrqyhytsWpdegvpesgaslldlvrqvskaqqksgagpiv
IHCSAGVGRSGTLMAVEIALQSIHTHFTLpDIKQIVSHLRVTgRAASVQTLQQYMLIWKVLLDFGVAYKQITE--EL
.|||||||| |. .||.| |. |. .. |. |.|..|| | . ||| .|| .|..|||.. .... .. .|
vhCsaGvGrtGvfiavdillerikaealv.Dvfqtvkqlreq.rnlmvqtedqyefiydvllealasgdtevdasdl
|
|||||||||
subfamily_Urchin-PTP-4_pd | Subfamily Urchin-PTP-4 | 265-520 | 9.6e-39 | 127.9 | In-house | 21-234 (392) | alignment | ||
Range on Protein: 265-520
Range on HMM: 21-234/392.0
DFKQEFSNLPGdPPSDLCTVFNHPVNNKKNRYSNIPCLDISRVQLKFkMPNKNSTDYIHANYIRSPFLKRGYILTQGPKKETRADFWRMIWQENTTAIVM
| .|| .||| |. || ....| ||||| || .| .||.|. . . . .||. | ||.| .. || .|||. . |||||..|||.|.|.|
lffeefhdlpg.pdiypqtvaqkeinlkknryknilpydsarvklev.iddipdsdylnasyipsfdnekayiasqgpnaaslddfwrmvfqenvttiam
LCQFLETNrekcaeyfprnahcclqfdkfsvnyedstvnkslvttrlnlsYEGETRLITHWLWKEWPDWQVPESSEVMLKILRKIRAR----STPPVIHC
. .. | . ..| .. . . |||| .||. . .||......| . | .|||
vtklkegd..........................................kgddartvaqfhftewPdkdvpkhtssllkfikevkadfGqythpliihc
SAGVGRSGTLMAVEIALQSIHThFTLPDIKQIVSHLRVtGRAASVQTLQQYMLIWKVLLD
||||||.| ..... . .. . |. ..|. .| | ||| .|| .|. .|.
sagvgrtgvvisidsvvahakk.trmvdvfnfvtnirr.krpymvqtkeqyafiygavle
|
|||||||||
0046845 | (Phosphotyrosine protein) phosphatases II | 266-525 | 3.1e-78 | 258.3 | In-house | 2-277 (284) | alignment | ||
Range on Protein: 266-525
Range on HMM: 2-277/284.0
FKQEFSNLPGDPPSD--LCTVFNHPVNNKKNRYSNIPCLDISRVQLKFKMPNKNSTDYIHANYIRSP-----FLKRGYILTQGPKKETRADFWRMIWQEN
...|| |. .. ..|...| | .||||..|...| ||| || .. ...|||.|.|.. . |. .|.||||...| .|||||.|..|
leeefeellsltvklllslsvallpenlsknRykdilpydhsRVklksldgdledsdYinAsyvdgydldltyikkkfIatqgPlpntvedFwrmvweqn
TTAIVMLCQFLETNREKCAEYFPRNaHCCLQFDKFSVNYEDSTVNKSLVTTRLNLSY---EGETRLITHWLWKEWPDWQVPESSEVMLKILRKIRAR---
.. ||||... | .||||| |.| . . .|....|.|.. . .|... ....| |.. .||.| .||. ...||| .||.|.| .|..||..|
vrvIVmltelvengrekcaqYwple.gevltygdftvtllseevkddytvrtleltnlgytgesrtvthfhytswpdhgvppspedlleflrlvrellen
---STPPVIHCSAGVGRSGTLMAVEIALQSIHTHFT--LPDIKQIVSHLRVtGRAASVQTLQQYMLIWKVLLDFGVAY
. | |.||||||||.||. |....|. .... . .|. ..|..|| | .||||.||... ..||.. .
lpgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlre.qRpgmvqtleqyrfvyealleylklk
|
|||||||||
DSPc_SM00195 | 266-521 | 3.4e-76 | 251.4 | In-house | 2-261 (263) | alignment | |||
Range on Protein: 266-521
Range on HMM: 2-261/263.0
FKQEFSNLPGDPPSDLCTVFNHPVNNKKNRYSNIPCLDISRVQLKFKmPNKNSTDYIHANYIRSPFLKRGYILTQGPKKETRADFWRMIWQENTTAIVML
.|.||..| ... .| ... |..||||.||.. | .||.|| . ..|...|||.||||. . |. ||.||||...| .|||||.|.|... ||||
lkeefekleestspketteaekkknksknRyknilpydhtrVklkke.ekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivml
CQFLETNREKCAEYFPRNAHCCLQFDKFSVNYEDSTVNK-SLVTTRLNLSYEG--ETRLITHWLWKEWPDWQVPESSEVMLKILRKIRAR----STPPVI
... | ..|||..|.|.... .|.|.||. . . | ..... |.|..|| ||| .|.. .|.||| .||.| . .|..||... . |.| |.
teeeengkekcdrywpeesggketfgkisvklvevekkkdeiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkkskstssgpivV
HCSAGVGRSGTLMAVEIALQSIHTHFTlPDIKQIVSHLRvTGRAASVQTLQQYMLIWKVLLDF
||||||||.||.....|.|........ .||..||..|| . |. .||||.||. | ...|..
hCsaGvgRtgtfvtidiilskleeekk.vdifeivkelR.kqRpgmvqtleqYlfiyeailey
|
|||||||||
PTPc_SM00194 | 266-521 | 3.4e-76 | 251.4 | In-house | 2-261 (263) | alignment | |||
Range on Protein: 266-521
Range on HMM: 2-261/263.0
FKQEFSNLPGDPPSDLCTVFNHPVNNKKNRYSNIPCLDISRVQLKFKmPNKNSTDYIHANYIRSPFLKRGYILTQGPKKETRADFWRMIWQENTTAIVML
.|.||..| ... .| ... |..||||.||.. | .||.|| . ..|...|||.||||. . |. ||.||||...| .|||||.|.|... ||||
lkeefekleestspketteaekkknksknRyknilpydhtrVklkke.ekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivml
CQFLETNREKCAEYFPRNAHCCLQFDKFSVNYEDSTVNK-SLVTTRLNLSYEG--ETRLITHWLWKEWPDWQVPESSEVMLKILRKIRAR----STPPVI
... | ..|||..|.|.... .|.|.||. . . | ..... |.|..|| ||| .|.. .|.||| .||.| . .|..||... . |.| |.
teeeengkekcdrywpeesggketfgkisvklvevekkkdeiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkkskstssgpivV
HCSAGVGRSGTLMAVEIALQSIHTHFTlPDIKQIVSHLRvTGRAASVQTLQQYMLIWKVLLDF
||||||||.||.....|.|........ .||..||..|| . |. .||||.||. | ...|..
hCsaGvgRtgtfvtidiilskleeekk.vdifeivkelR.kqRpgmvqtleqYlfiyeailey
|
|||||||||
0045450 | (Phosphotyrosine protein) phosphatases II | 266-521 | 2.3e-74 | 246.2 | In-house | 29-303 (307) | alignment | ||
Range on Protein: 266-521
Range on HMM: 29-303/307.0
FKQEFSNLPGDPP--SDLCTVFNHPVNNKKNRYSNIPCLDISRVQLKFKMPNKNSTDYIHANYI--------RSPFLKRGYILTQGPKKETRADFWRMIW
...|| |. . .. ......|.| .||||..|...| .||.|. .. ...|||.|.|. .. ||| .|.||||..|| .|||||.|
llkefekllsvtvfllgeysiallpenkdknrykdilpydhtRVklssldgsledsdYiNAsyvrvpllllldgydlkrkfIatqgPlpetvedFwrmlw
QENTTAIVMLCQFLETNREKCAEYFPRNaHCCLQFDKFSVNYEDSTVNKSLVTTRLNLS---YEGETRLITHWLWKEWPDWQVPESSEVMLKILRKIRA-
....|.||||... | .|||||.|.| . |....| |.. . .. .... ..|... ..||.| .||. ...||| .||.| | .|......|.
eqgvtvivmltelvelgrekcaqywPde.geeltygnftvtllseehldgytvrtlevtdldgtgesrtvthfhytgwpdhgvppsfeelldfieevrka
-----RSTPPVIHCSAGVGRSGTLMAVEIALQSIHTHFTL--PDIKQIVSHLRvTGRAASVQTLQQYMLIWKVLLDF
...| ..||||||||.||..| ..|. .... || .|. ..|..|| | .||...||. . ..||..
leelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllr.eqRpgavqnpeqyrflyeallel
|
|||||||||
subfamily_PTPRG_pd | Subfamily PTPRG | 266-521 | 2.3e-50 | 166.4 | In-house | 21-286 (563) | alignment | ||
Range on Protein: 266-521
Range on HMM: 21-286/563.0
FKQEFSNLPGDPPSD--LCTVFNHPVNNKKNRYSNIPCLDISRVQLKFKMPNKNSTDYIHANYIRSPFLKRGYILTQGPKKETRADFWRMIWQENTTAIV
|..|| .| |. .. ..| | .||||.|| | |||.|. .|.. ||| |||| .. .| |||| |.| |||||||..|.. ||
fseefealqsetiskdldaehsqkpenkrKnRylnivaydrsRvklsplpgkkkklDYinAnyidGyqkskafiatqgplkdtfddFWrmiWeqnvaiiv
MLCQFLETNREKCAEYFPRnaHCCLQFDKFSVNYEDSTVNKSLVTTRLNLSY-----E---GETRLITHWLWKEWPDWQVPESSEVMLKILRKI-RARST
|. .. | .|.|| |.|. .......|. ... | . . .| . . . .|.... . .||| .|||.| |. .| .|. .
mitnlvergrrkcdvYWPk..desetygalqvtlieeevlalytvrtlviknlklkkkkqcdteklvrqyhytkWPdhgvPehslpvLifvkkssaanka
---PPVIHCSAGVGRSGTLMAVEIALQSIHTHFTLpDIKQIVSHLRVTgRAASVQTLQQYMLIWKVLLDF
| |.||||||||.||..... |. |... . .. ... |.| | ||| ||. ....||.
eaGPivvHcsaGvgrtGtyivldtllkqiqqenav.nvfgflkhiraq.RnflvqteEqYiflhdallea
|
|||||||||
subfamily_PTPRK_pd | Subfamily PTPRK | 266-524 | 4e-50 | 165.4 | In-house | 24-279 (314) | alignment | ||
Range on Protein: 266-524
Range on HMM: 24-279/314.0
FKQEFSNLPGDppsdlCTVFNHPVNNKKNRYSNIPCLDISRVQLKfKMPNKNSTDYIHANYIRSPFLKRGYILTQGPKKETRADFWRMIWQENTTAIVML
||.|. .|. . .. |..|||. .| | |||.|. . . .|.||| |..| | . .| ||||..|| .||||....||...||||
fkeeyeslfeg.....wdaakkdenreknrsgdilaydrsrvfli.tidgdpssdyinaalidsykrpaafivtqgPlqetvkdfWrlvydencasivml
CQFLETNREKCAEYFPRNAHC--CLQFDKFSVNYEDSTVNKSLVTTRLNLSYEgETRLITHWLWKEWPDWQVPESSEVMLKILRKIRARST----PPVIH
.. |. | || .|.| ... .. ... . |.. . ..|. ..| |.|.. .. . |||..|| | . .||..|.. . . . |.|
telvevgrvkClkyWPedtevygdikvelvetellaelvvrifrveklargqe.eirevrqfqflgWpdhdvPvsatgllklvrrvkksqeeeaGrivvh
CSAGVGRSGTLMAVEIALQSIHTHFTLpDIKQIVSHLRVTgRAASVQTLQQYMLIWKVLLDFGVA
|||| ||.|| .|..| |. |... .. |. ..| || . . |.| .||..|. |.|. ..
CsaGaGrtGtfiaidivldmieregvv.dvfnavktlrsr.kvnmveteeqykfiydvileaclc
|
|||||||||
subfamily_PTPN14_pd | Subfamily PTPN14 | 266-521 | 1.1e-46 | 154.2 | In-house | 25-295 (300) | alignment | ||
Range on Protein: 266-521
Range on HMM: 25-295/300.0
FKQEFSNLPGDPPSDLCTVFNHPVNNKKNRYSNIPCLDISRVQLKFKmpNKNSTDYIHANYIRSPF--LKRGYILTQGPKKETRADFWRMIWQENTTAIV
.|. ..| |... . |.|..|||. .. . .||.|. ..|||.|| | |. . .| || .||| . | |||.|.|..... ||
vfteyeripkkredallstaklpenaeknrfkdvlPyednrvelspt..kenstgyinassikvsvggkersyivaqgPleltvqdfWqmvWeqgvqliv
MLCQFLETNREKCAEYFPRN--AHCCLQFDKFSVNYEDSTVNKSLVTTRLNLSY--EGETRLITHWLWKEWPDWQVPESSEVMLKILRKIRA---R----
|| . | .||. .|||.. . ..|.|| | . |. .|..|| |.| . .| | . | ...||| .||| . .|. |..... .
mlteeeedgkeksfkyfPkleskkktvefgkfkvttkfsedsdsvittglklkhlpskeertvwhlqytDWpdhgvPeDvkgflsyLeevqsvrrktnse
------STPPVIHCSAGVGRSGTLMAVEIALQSIHTHFTLpDIKQIVSHLRvTGRAASVQTLQQYMLIWKVLLDF
. | ..||||||||.| |. ... ...... .. |||.....|| . | |||| || ..|||. .
veskeskPPvlvhCsaGvGrtGvlilsdlliatlehneei.dikkvlarLr.eqrmllvqtlaqYkfvYkvliky
|
|||||||||
subfamily_Cele-PTP-18_pd | Subfamily Cele-PTP-18 | 267-535 | 6.9e-51 | 167.8 | In-house | 25-300 (305) | alignment | ||
Range on Protein: 267-535
Range on HMM: 25-300/305.0
KQEFSNLPGDPPSDLCTVFNHPVNNKKNRYSNIPCLDISRVQLKFKMPNknstDYIHANYIRSPFLKRGYILTQGPKKETRADFWRMIWQENTTAIVMLC
..||... . | . ...|||| .. ||| ||.|. | .||||||. .| . .| || | ..| |||| | .|.. || |||
raefvamkrfndfekmkafkeaqeagknrykdvgcldnnrvklegpwph....eyihanyvstptnpkrfictqaplektcadfwymclqdkveaifmlc
QFLETNREKCAEYFPRNAHCCLQFD----KFSVNYEDSTVNKS-------LVTTRLNLSYEG-ETRLITHWLWKEWPDWQVPESSEVMLKILRKIRARST
..|| .||.|||. . . |.|. | || .| |. | . | | . | ..| .||. | .||| || . .|..| | |.
nllekgakkcleyfaskdkdvlefeekgqkisvkfessvtlkfrkdakakvtetvlviegpgekarkvthyhwidwpdrgvpaadlailellekarpskg
PPVIHCSAGVGRSGTLMAVEIALQSIHTHFTLPDIKQIVSHLRVtGRAASVQTLQQYMLIWKVLLDFGVAYKQITEELAEK
| |.|||||.||.|... .| |. . . . | ..|. ..| | |.|| .||... .|.|.. | . || |
pivvhcsagigrtgsvvmleyildqllagqiiedtdkilqkire.qrnnsiqtdaqylfvhqvilnyfrkkklldeevkea
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 268-451 | 6.6e-24 | 79.1 | In-house | 9-192 (319) | alignment | ||
Range on Protein: 268-451
Range on HMM: 9-192/319.0
QEFSNLPgdppS-----DlctvfNHPV-NNKKNRYSNIPCLDISRVQLKfKMPNKNSTDYIHANYIRSPFL-KRGYILTQGPKKETRADFWRMIWQENTT
.|| .|| | . || ..|.|. |. | .|| |. ........ |..|.|.| . . || .| . ... .||||..|. ..
eefrdlP....qliarad.....evPvtskdksrvinvvPlPetrvvlq.rigdddkdeyldasyvrGyddapnsyiaaqvsledsssdfwrtvweqqsr
AIVMLCQFLETNREKCAEYFPRNAHC--CLQFDKFSVNYEDSTVNKSLVTTRLNLS-Y-EGETRLITHWLWkEWPDWQVPESSEVMLKILRKIRA
|| |.. | ..||||.| .. . .. | . |.. ... | | . |.| .||. . .|.. .|| . . .. .| ..|.
vivqltdlselGikvcaeylPtketldntslyGdilvtlkgrevkdryaistlllkrvdkeesrelthywy.kwleaevPaeeaaliamllevrs
|
|||||||||
subfamily_PTPN3_pd | Subfamily PTPN3 | 269-517 | 4.2e-51 | 168.5 | In-house | 20-270 (280) | alignment | ||
Range on Protein: 269-517
Range on HMM: 20-270/280.0
EFSNLPGDPPSDLCTVFNHPVNNKKNRYSNIPCLDISRVQLKfkmpnKNSTDYIHANYIR----SPFLKRGYILTQGPKKETRADFWRMIWQENTTAIVM
.| .| |. ... . | | .|||| .| |. ||.|| ...|||| |||. | | || |||| ..| .|||.|.|..... |||
qfeqlyrkkpglaisaarkpenlsknryrdilpydatrvklk.....esetdyinanyvnmeipstglvnryiatqGPlaktatdfWqmvweqksslivm
LCQFLETNREKCAEYFPRNAHcCLQFDKFSVNYEDSTVNKSLVTTRLNLSYEG--ETRLITHWLWKEWPDWQVPESSEVMLKILRKIRA----RSTPPVI
| . .| | || .|.|.. . |.. .|||. | . .|| |. | |. . | | |.. . .||| .||..|. .|......|. ...| |.
lttlverGrvkChqyWPeted.eleygefsvkcekedetksyvlrelvlkdketkeerkilqlqylaWpdhgvPddsadflefvervrklrsgkeePvvv
HCSAGVGRSGTLMAVEIALQSIHTHFTLpDIKQIVSHLRvTGRAASVQTLQQYMLIWKV
|||||.||.| |...|.||. | .. . . .||...| ||. ||| .|| .. .
hCsaGigrtGvlilletalalieaaepv.ypldivrtmr.dqramlvqtasqykfvCea
|
|||||||||
subfamily_Cele-PTP-17_pd | Subfamily Cele-PTP-17 | 273-379 | 6e-09 | 29.9 | In-house | 21-127 (347) | alignment | ||
Range on Protein: 273-379
Range on HMM: 21-127/347.0
LPGDPPSDlCTVFNHPVNNKKNRYSNIPCLDISRVQLKFKMPNKNS----TDYIHANYIRSPFLKRGYILTQGPKKETRADFWRMIWQENTTAIVMLcqf
| . ||. .|. . . .||| . | .|| | . ... || | .|. .. ||||| | .| |||.|. . | .| .
lanyspsk.ftsvewekslsknrskdvklidatrvvlspeksknsraddvetyinashikfdnaskeyiltqyplpdtvrdfwkmvsvtkvtqvvti...
LETNREKCAEY
.| .... |
fepikdeaiee
|
|||||||||
0049772 | (Phosphotyrosine protein) phosphatases II | 277-524 | 1.1e-42 | 142.2 | In-house | 33-282 (314) | alignment | ||
Range on Protein: 277-524
Range on HMM: 33-282/314.0
PPSDLCTVFNHPVNNKKNRYSNIPCLDiSRVQLkfKMPNKNSTDYIHANYIRSPflkRGYILTQGPKKETRADF----------WRMI--WQENTTAIVM
.|. ..|.....| .|||| .|.. | .||.| . . ...|||.|.|.... . .| ||||...| || |||. .. |. |||
lpeltilvadlflnrdknryldilpad.nrvil..pglpvsgsdyinasyvdgf...lkfIatqgpleitvvdfreepvlyyngwrmvlrgdlnvrdivm
---------------------LCQFLETNREKCAEYFPRNAhcclqfdkfSVNYEDSTVnkslvttrlnlsyegeTRLITHWLWKEWPDWQVPeSSEVML
|... . . | .|.... .. |... . .||. ..|. .||...| ..| ..
srdevladelsrLdaAlgKtpllildgngneptaadlellk.........eelydpelf................erlgikylripvpDgsap.lledfd
KILRKIRA--RSTPPVIHCSAGVGRSGTLMAVEIALQSIhtHFTLPDIKQIVSHLRV-TGRAASVQTLQQYMLIWKVLLDFGVA
..|. |.. . .| ..||.||.||.||.... . . ...| .. . | | . ....|.|| |...||..
eflefieeadkggpvlvHCkaGkgRtgtfvvaaylmkll..gvsleealedvrlkRpinpnpgfieqleqyefilealleylkf
|
|||||||||
subfamily_Cele-PTP-11_pd | Subfamily Cele-PTP-11 | 278-541 | 2.2e-35 | 116.9 | In-house | 33-297 (312) | alignment | ||
Range on Protein: 278-541
Range on HMM: 33-297/312.0
PSDLCTVFNHpvNNKKNRYSNIPCLDISRVQLKfkmpnKNSTDYIHANYIRSPFLKRGYILTQGPKKETRADFWRMIWQENTTAIVMLCQFLETNREKCA
. || | . . ||| || | | | | . |||||... .. |||| ..| . ||.. .|.|..|| |.| ||||
sdsectaflk..fkdlnrypniqcwdrgrftla.....gdenfyihanfvkictkperfvctqgplentcthfwqlalslgstsiillcgfvedgsekca
EYFPRnAHCCLQFDKFSVNYEDST------VNKSLVTTRL---NLSYEGETRLITHWLWKEWPDWQVPESSEVMLKILRKIRARSTPPVIHCSAGVGRSG
.| .... | | | | .| |. . |. . |. | ||| .|.| . |..| .. | . ||||||||.|
kyisd.ivgfvdledhrvyteycteieiggkskdkithrvlkvvvkatgqesklnhyqwaswpdhgmpdscdtalrllsavkkdkkpviahcsagvgrtg
TLMAVEIALQSIhTHFTLPDIKQIVSHLRvTGRAASVQTLQQYMLIWKVLLDFGVA---YKQiTEELAEKFNSTYR
||. .| . .. | ..|.. || || ||... ||. ...|.| . ||. |. ||. ||
tlaliesmiaal.rhprkqnvkdsfvllr.kdrarsvrvfpqyvyalrcvleflyskglykr.neqewtkfketya
|
|||||||||
subfamily_CG7180_pd | Subfamily CG7180 | 278-524 | 2.6e-35 | 116.5 | In-house | 30-292 (296) | alignment | ||
Range on Protein: 278-524
Range on HMM: 30-292/296.0
PSDLCTVFNHPVNNKKNRYSNIPCLDISRVQLKfKMPNKNSTDYIHANYIRSPFLKRGYILTQGPKKETRADFWRMIWQENTTAIVMLCQFLETNReKCA
.. | . | .|||. .. | || |. |. ....||| | |. | |. || |..||||| .|||....|.. |.|.|.. . .. ..
eigdCagglrkenreknrdvkvvPyDynRvvLe.kldGeeksdYinavyvdsflkkkeyivteapkketvdefWrlvydeeisavvvLtktfdfak.myp
EYFPRNAhcCLQFDKFSVNYEDSTV-----------NKS-LVTTRLNLSYEGETRLITHWLWKEWPD-WQVPESSEVMLKILRKIRA---R------STP
.|.| .. |. .. |.. . .| . .| . . |||.... ..||. .|| |.. .....|..| . |
sywpnks..keqygeifveiveekqyanlkirtfkltkkivalteqekqvkaetRivklfqlteWeledkvPlstnalielrrrvrlwrekvdedpeegP
PVIHCSAGVGRSGTLMAVEIALQSIHTHFTLpDIKQIVSHLRVtGRAASVQTLQQYMLIWKVLLDFGVA
|...| |..||| .|....|. .. . . |. . | || | |.. ..|. |. |||.. ..
vvvvssdGasRsGvylaidanlelvekeeev.dvFeavktlrr.sRpqLvenveeYkyiYdvlleavlc
|
|||||||||
subfamily_Cele-PTP-15_pd | Subfamily Cele-PTP-15 | 281-523 | 6.3e-37 | 122.1 | In-house | 26-271 (285) | alignment | ||
Range on Protein: 281-523
Range on HMM: 26-271/285.0
LCTVFNHPVNNKKNRYSNIPCLDISRVQLKfkmpnKNSTDYIHANYIRSPFLK-RGYILTQGPKKETRADFWRMIWQENTTAIVMLCQFLETNREKCAEY
|| . | |||... |.. .|| || . |||||...| | || |||| || .|||.||.||. . ..||| ..| |||| |
nctytayeanpdlnryadvrcieetrvvlk.....nhdrdyihaswmrmpgkdqstyittqgplpetlsdfwhmiyqekiayvlmlctlfeggvekcaly
FPRNAHCCLQFDKFSVNYEDS-------TVNKSLVTTRLNlSYEGETRLITHWLWKEWPDWQVPESSEVML---KILRKIRARSTPPVIHCSAGVGRSGT
.| . ..| |. . . |. ..| . . | . | ||| || . |. | ..|. . .| ..||||||||. |
ypeklgevvkfgkyeitlteckeeaiagtilnaltvinte.dasseplymnhvqvpwwpdqlapedarpmielykwvkkvnpkekpicvhcsagvgrtat
LMAVEIALQSIHTHFTLpDIKQIVSHLRVTgRAASVQTLQQYMLIWKVLLDFGV
.. .. | | . .. .|| .| | .||. |..... ||... .
fvgidyatirimenpni.emldivremram.rfqavqshmqflflyvvlmeyfi
|
|||||||||
0040439 | (Phosphotyrosine protein) phosphatases II | 282-521 | 2e-67 | 222.7 | In-house | 3-245 (249) | alignment | ||
Range on Protein: 282-521
Range on HMM: 3-245/249.0
CTVFNHPVNNKKNRYSNIPCLDISRVQLKFkMPNKNSTDYIHANYIRSPFLKRGYILTQGPKKETRADFWRMIWQENTTAIVMLCQFLETNREKCAEYFP
..|...|.| .||||..|...| |||.|. .|. . .|||.|.|| . || .|.|||| .|| .|||||.|... |.||||... | .|||||.|.|
ysvallpenkdknrypdilpydhsrvklsi.lpglflsdyinAsyidgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqywp
RnaHCCLQFDKFSVNYEDSTVNKSLVTTRLNLS--YEGETRLITHWLWKEWPDWQVPESSEVMLKILRKIRA------RSTPPVIHCSAGVGRSGTLMAV
|....|.|.. . .|....... | |. |.||.| ..|. . ||| .||.| | .|......| ...| ..||||||||.||. |
l..ggsleygdftvtllsvevkddytvrtleltnlydgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtfiaa
EIALQSIHTHFTlPDIKQIVSHLRVTGrAASVQTLQQYMLIWKVLLDF
..|. .... . |....|..|| .||...||. . ..||..
ylmleqlekelg.vdleeavkllrsqR.pgavqnpeqyrflyeallel
|
|||||||||
0042113 | (Phosphotyrosine protein) phosphatases II | 282-520 | 2.6e-67 | 222.1 | In-house | 1-241 (245) | alignment | ||
Range on Protein: 282-520
Range on HMM: 1-241/245.0
CTVFNHPVNNKKNRYSNIPCLDISRVQLKfKMPNKNSTDYIHANYIRSPFLKRGYILTQGPKKETRADFWRMIWQENTTAIVMLCQFLETNREKCAEYFP
..|...|.| .|||||.|...| .||.|. ... . .|||.|.|. . ....|.|||| .|| .|||||.|... |.||||... | .|.|||.|.|
ysvallpenkdknrysdilpydhtrvkls.pdggdldsdyinasyvdgyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywp
RnaHCCLQFDKFSVNYEDSTVNKSLVTTRLNLS--YEGETRLITHWLWKEWPDWQVPESSEVMLKILRKIRA-----RSTPPVIHCSAGVGRSGTLMAVE
.. |....|.|.. . ......... |... ...|.| ..|... ||| .||...| .|..|. .| ...| ..||||||||.||..|.
l..gesltygdftvtllseehlddytvrtlevtnlgddesrevihyhylpwpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaay
IALQSIHTHfTLPDIKQIVSHLRVTgRAASVQTLQQYMLIWKVLLD
..|. .... .. ..| .|| | .|||..||. . ..||.
lmleqleke.lgvsleeavkelrsq.Rpgavqtpsqyrflyealle
|
|||||||||
0037934 | (Phosphotyrosine protein) phosphatases II | 282-519 | 9.2e-62 | 204.1 | In-house | 2-239 (243) | alignment | ||
Range on Protein: 282-519
Range on HMM: 2-239/243.0
CTVFNHPVNNKKNRYSNIPCLDISRVQLkfkmpnkNSTDYIHANYIRSPflkRGYILTQGPKKETRAD----FWRMIWQENTTAIVMLCQFLETNREKCA
......|.| .|||||.|...| ||| | ...|||.||.|. . ...|.|||| .|| .| ||||.|....|.||||... | .|||||
fsiallpenlsknrysdilpydhsrvkl.......egsdyinanliyvt...prliatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekca
EYFPrNAHcclQFDKFSVNYEDSTVNKSLVTTRLNLSY---EGETRLITHWLWKEWPDWQVPESSEVMLKILRKIR------------ARSTPPVIHCSA
.|.| . . ....|.|.. .... .. . . | |.. ...|||..|... ||| .||.| | .|..|...| .. | ..||||
qywp.gev...tygdftvtllseehlddytvrtlllenldlddltrlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsa
GVGRSGTLMAVEIALQSIhtHftlPDIKQIVSHLRVTGRAASVQTLQQYMLIWKVLL
||||.||| | . |. . . |. ..| .|| .|||..||. . ..||
GvgRtGtliaaylmllll..g...vdleeavkllreqRpgkavqtpsqyrflyeall
|
|||||||||
subfamily_PTPN1_pd | Subfamily PTPN1 | 282-515 | 3.9e-52 | 171.8 | In-house | 24-264 (290) | alignment | ||
Range on Protein: 282-515
Range on HMM: 24-264/290.0
CTVFNHPVNNKKNRYSNIPCLDISRVQLKfkmpnKNSTDYIHANYIRSPFLKRGYILTQGPKKETRADFWRMIWQENTTAIVMLCQFLETNREKCAEYFP
... ..| |...||| .. | ||..|. ....||| |. . . .|| ||||||| .| . ||.|.|.... |.||| ...| .. |||.|.|
treaklpenrnlnryrdvspydhsrikle.....radndyinaslveleeakrsyiltqGPlpntvdhfWqmvWeqkskavvmlnkvvekeqikcaqywP
RNAH-CCLQFD--KFSVNYEDSTVNKSLVTTRLNLSY--EGETRLITHWLWKEWPDWQVPESSEVMLKILRKIRAR------STPPVIHCSAGVGRSGTL
.. . .|... |..|.. ... . |.| ||| |.|. . |||. |||| .|| | |.| |.|||||||.|||||.
qgeeekellledtklkvkliseerksyytvrllelenlktqetreilhfhyttwpdfgvpespaaflkflfkvresGslssdvGpavihcsaGiGrsGtf
MAVEIALQSIHTHFT--LPDIKQIVSHLRVTgRAASVQTLQQYMLIW
. |. | |. . |||. . .|| | .|| .| . .
clvdtclvliekkddlssvdikkvllelrky.rlGliqtadqlrfsy
|
|||||||||
subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 283-522 | 1.8e-45 | 150.6 | In-house | 18-258 (284) | alignment | ||
Range on Protein: 283-522
Range on HMM: 18-258/284.0
TVFNHPVNNKKNRYSNIPCLDISRVQLKFKMpNKNSTDYIHANYIRSPFLKRGYILTQGPKKETRADFWRMIWQENTTAIVMLCqfletnREKCAEYFPR
| | . | |||. .| | ..|.|. . .. .||| | .| | || ||||...| ||||||||. |...||.| ..||..|.|
tfanldqnkdknrighilafdknvvklerli.GeefsdyinasfitGyqrkdkyiatqGPldntladfWrmiweyncstivllt......kdkcsqywpl
NAHccLQFDKFSVNYEDSTVNKSLVTTRLNLSY---EGETRLITHWLWKEWPDWQVPESSEVMLKILRKIR------ARSTPPVIHCSAGVGRSGTLMAV
.. . ..| |. . . . | ..|| | . | |. . .. ||| ||... ......|.| .. |.||||||||.|. ...
kiv..ikeerfkvkvdsveeseeyvvrdielsedgkekdirkirqfhflgwpdvgvpdypsdlmrlvkkvrhltskenhranivvhcsagvgrtgvyivl
EIALQSIHtHFTLPDIKQIVSHLRVtGRAASVQTLQQYMLIWKVLLD---FG
.. |. .. . |. ..| || | || | ||..|. ||. ||
dvlldrmk.eekqvdvynfvrdlrq.qrntlvqdlvqykfiysalleehlfg
|
|||||||||
subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 284-524 | 1.5e-49 | 163.5 | In-house | 3-244 (250) | alignment | ||
Range on Protein: 284-524
Range on HMM: 3-244/250.0
VFNHPVNNKKNRYSNIPCLDISRVQLKFKMpNKNSTDYIHANYIRSPFLKRGYILTQGPKKETRADFWRMIWQENTTAIVMLCQFLETNREkCAEYFPRN
| ..| |..||||..| || ||| |. . . .||| | .. . .. .| |||| ..| |||||...|....|||| .. |.... . .|.| .
vakkpqnkeknryadiialdssrvvLekek.gdkesdyinasflhgyderkafiatqgPlqatiedfWrmvleeksgtivmLtnLkesekt.yhqywPve
AhcCLQFDKFSVNYEDSTVNKSLVTTRLNLSYEGET--RLITHWLWKEWPDWQVPESSEVMLKILRKIRAR-----STPPVIHCSAGVGRSGTLMAVEIA
.. . |. .. . .....| || . .. |.. . . ||| ||| . .|..|.|..| ..| ...|||||||||. .|..
k..aekyGdvtvsllskeefadytkrklklskakkaderivrqlhfvvWPdkgvPevatavLellkkvqasqqqagnaPvivqCsaGvgrsGafiaidav
LQSIHTHFTLpDIKQIVSHLRVtGRAASVQTLQQYMLIWKVLLDFGVA
|. ... .. |. ... || | .|..|.||. .....| . ..
lerlkkekvv.dvfkvikvlrk.drphavesleqyvfvyeiilkalds
|
|||||||||
subfamily_PTPRN_pd | Subfamily PTPRN | 285-516 | 1.5e-36 | 120.6 | In-house | 51-286 (297) | alignment | ||
Range on Protein: 285-516
Range on HMM: 51-286/297.0
FNHPVNNKKNRYSNIPCLDISRVQLKFKMpNKNSTDYIHANYIRSPF-LKRGYILTQGPKKETRADFWRMIWQENTTAIVMLCQFLETNREKCAEYFPRN
... | ||||.... | |||.|| . .....||| | | . || |||| .| ||||.|.|.. .. ||.|.. |.. ..|..|.| .
akaeknvkknrskavlpydhsrvklkeea.saeksdyinasaildhdprapayiatqgplastvadfwqmvweqGvvvivnltrleeegvkqckrywpde
AHCCLQFDKFSVNYEDSTVNKSLVTTR-LNLSYEGETRLITHWLWKEWPDWQVPESSEVMLKILRKI----RARSTPPVIHCSAGVGRSGTLMAVEIALQ
. .. . . | . || . | ||| .| . . ||. .|| |. .|. ||. | ||.| |.|||.|.||.|. ..... |.
GsevyhiyevhlvsehiwcddylvrsfylknlqtsetrtvtqfhflswpeegvPasaksllefrrkvnksyrGrscpivvhcsdGaGrtGvyilidlvln
SIHTHFTLPDIKQIVSHLRvTGRAASVQTLQQYMLIWK
. || . ||| |. |.| .|. ....
rllkGvkeidiaatlehlr.dqrpglvktkdqfefalt
|
|||||||||
subfamily_PTPN12_pd | Subfamily PTPN12 | 286-523 | 5.9e-60 | 197.6 | In-house | 36-278 (290) | alignment | ||
Range on Protein: 286-523
Range on HMM: 36-278/290.0
NHPVNNKKNRYSNIPCLDISRVQLKFKMPNKnSTDYIHANYIRSPFLKRGYILTQGPKKETRADFWRMIWQENTTAIVMLCQFLETNREKCAEYFPRNAH
....| ||||| .| | |||.|. . .. ||| ||.|. . | || .||| .| |||||||. |.. .||.|. .| .. ||. |.| . .
ekeenvkknrykDilPydksrvelskieeee.gsdYinanfikgvegkleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkkCerYWpeege
CCLQFDKFSVNYED-STVNKSLVTTRLNLSYEGETRLITHWLWKEWPDWQVPESSEVMLKILRKIRA----RSTPPVIHCSAGVGRSGTLMAVEIALQSI
|.|..|.|. |. .|.. .. |.. ..|.| .. . ...||| .||.| . .|......| ..| |.|||||||| ||..|.... . .
eelefgefevtleeekavdddflirtLkveaqkesrkvyqfhYtaWPDhgvPssaksllelielvrelqesedaPlvvhCsaGvGrtGtiiaidyvrell
HTHFT--LPDIKQIVSHLRvTGRAASVQTLQQYMLIWKVLLDFGV
... . |. ..| .|| . ||| ||| .|| |..| ....
kaekipeeldvfdlvlelr.kqraalvqtkeqyelvykavaelvq
|
|||||||||
subfamily_Sponge-PTP5_pd | Subfamily Sponge-PTP5 | 287-521 | 2.6e-47 | 156.0 | In-house | 30-265 (283) | alignment | ||
Range on Protein: 287-521
Range on HMM: 30-265/283.0
HPVNNKKNRYSNIPCLDISRVQLKFKMPnknstDYIHANYIR---SPFLKRGYILTQGPKKETRADFWRMIWQENTTAIVMLCQFLETNREKCAEYFPRN
|..|||. .| | ||.|| . . ||| | .| | ...|| .|.| ..|. |||.|...|. |||||| .. | .|.||. |.|..
adenkrknrnqeivpadqwrvelksesr.....dyinavfipvsksykqdkkyiiaqsPldrtvvdfWkmvfdekitaivmltklqedlrikCsqyWPkr
AhcCLQFDKFSVNYEDSTVNKSLVTTRLNLSYE---GETRLITHWLWKEWPDWQVPESSEVMLK---IL-RKIRARSTPPVIHCSAGVGRSGTLMAVEIA
.. .| | .. | ..|.. | | .. .| |..|. .| ... . ..| . . . . .| |.|||.|.||.....|. .
G..sedyGeftvtlrkettsnsfiikelllrvnssakstlllahyqvidWleygeqaiinslvkfnkvislqteskkgPivvhCstgiGrtavfiaasas
LQSIHTHfTLPDIKQIVSHLRVTgRAASVQTLQQYMLIWKVLLDF
.. . |. .. |. ..| .|. | ||||.||.|. .. |.
vkdalte.svvdvfavvkimreq.rmmavqtldqyklvhelvleq
|
|||||||||
subfamily_ptpA1_pd | Subfamily ptpA1 | 287-488 | 1.8e-35 | 117.5 | In-house | 44-264 (418) | alignment | ||
Range on Protein: 287-488
Range on HMM: 44-264/418.0
HPVNNKKNRYSNIPCLDISRVQLKfKMPNKNSTDYIHANYIRSPFLKRgYILTQGPKKETRADFWRMIWQENTTAIVMLCQFLETNREKCAEYFPRNAHC
. | ||||.|| .. .||||| |. .|. .||| |||| . |. .| |||| .| ||||||.|.. |||| . | | || |.| .
kkhntsknrytnilpvnhtrvqlk.kiqdkegsdyinanyidgaypkq.fictqgplpntiadfwrmvwenrcriivmlsresencrikcdrywpeqigg
---------CLQFDKFSVNYEDST--VNKSLVTTRLNLSYEGETRLITHWLWKEWPDWQVPESSEVMLKILRKIRAR----------STPPVIHCSAGVG
| .||. . .. ..| . |..||||| ||.. .. ||| ..|. .. . ..|. | | | ..|||||||
eqfsiygngnevfgtysvelveviqdpereiitrnirltfegetrditqyqyegwpdhnipdhtqpfrqllhsitnrqnqiipssdrnvpiivhcsagvg
RSGTLMAVEIALQSIHTHFTLPD
|.||. . | .. . .| |
rtgtfctavimmkkldhyfkqld
|
|||||||||
subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 288-519 | 3.3e-37 | 122.9 | In-house | 5-237 (239) | alignment | ||
Range on Protein: 288-519
Range on HMM: 5-237/239.0
PVNNKKNRYSNIPCLDISRVQLKfKMPNKNSTDYIHANYIRSP-FLKRGYILTQGPKKETRADFWRMIWQENTTAIVMLCQFLETNREKCAEYFPRNAHc
||. ||||.|| | ||| |. |. | .||| |.|.| . || ||| . . |||||.||| |||| ..| ..|| .|.| ..
rvnkaknryanivtydhsrvvle.klsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpdsts.
clQFDKFSVNYEDSTVNKSLVTTRLNLSY--EGETRLITHWLWKEWPDWQVPESSEVMLKILRKIRARST----PPVIHCSAGVGRSGTLMAVEIALQSI
.. .. | . | . . .| . | | . .. . ||| ||. . .| . ||| | | ||||||||||.|... .. |.
..kycnlrvtlrktevfadyiirtfvmsqvgqteeryvyqyhftvwpdkgvpqyatavlglrrkitkdslpgarpwvihcsagvgrtgaflvidamlrqa
HTHFTLpDIKQIVSHLRVtGRAASVQTLQQYMLIWKVLL
. . |. || . | .| | ||| .||..| .|
kkqktv.difnyvkaire.drphmvqtseqyvfihlavl
|
|||||||||
subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 288-519 | 3.7e-37 | 122.8 | In-house | 6-238 (239) | alignment | ||
Range on Protein: 288-519
Range on HMM: 6-238/239.0
PVNNKKNRYSNIPCLDISRVQLKfKMPNKNSTDYIHANYIRSP-FLKRGYILTQGPKKETRADFWRMIWQENTTAIVMLCQFLETNREKCAEYFPRNAHc
||. ||||.|| | ||| |. |. | .||| |.|.| . || ||| . . |||||.||| |||| ..| ..|| .|.| ..
rvnkaknryanivtydhsrvvle.klsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpdsts.
clQFDKFSVNYEDSTVNKSLVTTRLNLSY--EGETRLITHWLWKEWPDWQVPESSEVMLKILRKIRARST----PPVIHCSAGVGRSGTLMAVEIALQSI
.. .. | . | . . .| . | | . .. . ||| ||. . .| . ||| | | ||||||||||.|... .. |.
..kycnlrvtlrktevfadyiirtfvmsqvgqteeryvyqyhftvwpdkgvpqyatavlglrrkitkdslpgarpwvihcsagvgrtgaflvidamlrqa
HTHFTLpDIKQIVSHLRVtGRAASVQTLQQYMLIWKVLL
. . |. || . | .| | ||| .||..| .|
kkqktv.difnyvkaire.drphmvqtseqyvfihlavl
|
|||||||||
subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 289-521 | 1.7e-53 | 176.3 | In-house | 19-263 (270) | alignment | ||
Range on Protein: 289-521
Range on HMM: 19-263/270.0
VNNKKNRYSNIPCLDISRVQLKfKMPNKNSTDYIHANYIR-SPFLKRGYILTQGPKKETRADFWRMIWQENTTAIVMLCQFLETNREKCAEYFPRNAHC-
..| ||| .| .||.|. .. ... | || |||.| |. || ..||.. | .||||||.|..|||||. .. | .|.||. |.| ...
rgkklnRyadiLPsPatRvrle.eleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpaepkek
-CLQFDKFSVNYEDSTVNKSLVTTRLNLSYEGETRLITHWLWKEWPDWQVPESSE------VMLKILRKIR------ARSTPPVIHCSAGVGRSGTLMAV
|.. | .| . .. .. ..|||.| ..||.| ..|. ...||| ||.... .||.||..| ....| ..||||||||.|||.|.
vkledgkikvlalseekeegyiltrlrleekgeerrlvHfwyntWpdhgvpreedsslstdqllkmlravrrsekeldkaePllvHcsaGvgRtGtlial
EIALQSIHTHFTLpDIKQIVSHLRvTGRAASVQTLQQYMLIWKVLLDF
.||.. .... . |. .|...|| | | ||. .|| ...|... .
DiavrlLeetkkv.dvlaiieelR.kdRmalvqhpeqyeflykavvey
|
|||||||||
subfamily_PTPN23_pd | Subfamily PTPN23 | 289-519 | 3.5e-45 | 149.0 | In-house | 42-277 (288) | alignment | ||
Range on Protein: 289-519
Range on HMM: 42-277/288.0
VNNKKNRYSNIPCLDISRVQLKfkmpnKNSTDYIHANYIRSPFL-KRGYILTQGPKKETRADFWRMIWQENTTAIVMLCQFLETNREKCAEYFPRNAHCC
.. .|||. .| | .||.|. .. ||| | .... .| ||.|...| .|||.|.... . |||| . |....|...|.| .
lyseknrsrdilPyDhnRvklr.....gskDDYinAsfvkdlspgcPdfiatqaPlqstlnDFWlmvyeqkssviVmllskeelgkpkvdrYwPedkget
LQFDKFSVNYEDSTVNKSLVTTRLNLSYEG--ETRLITHWLWKEWPDWQVPESSEVMLKILRKIRA--------RSTPPVIHCSAGVGRSGTLMAVEIAL
.|...|| .. . . | |.|. .. ... ..| ...||. ||.| |..|..| .... || |.||||||||.|.. | |.
vkfgdlsvtlksvretethvervlkletldadavksvshlqltsWpelGvPasPetllqfldevesayeavqrksktPlvvhCsaGvgRtgvfalvyaav
QSIHTHFTLPDIKQIVSHLRVTgRAASVQTLQQYMLIWKVLL
. .... |.|| |.||.|| | .||. .|. ... |
relekgnglldiiqvvsrlreq.Rrfmvqekeqlkfsyeavl
|
|||||||||
subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 289-524 | 7.3e-25 | 82.5 | In-house | 32-259 (267) | alignment | ||
Range on Protein: 289-524
Range on HMM: 32-259/267.0
VNNKKNRYSNIPCLDISRVQLKFKMPNknstdYIHANYIRSPFLKRGYILTQGPKKETRADFWRMIWQENTTAIVMLCQFLETNrekCAEYFPRNAHCCL
|...||. . | .|| |. | . || | |. . |. .|.||.| | | .||. .| ... . ||.| . . | ..| . .
knqernrlddnlpyddtrvilrtkeee.....yinasyvegyktknafivtqdplkntitdfltvihdqkvpvivlltkvftdn...irlfwPPkmgqak
QFDKFSVNYE--DSTVNKSLVTTRLNLSYEGeTRLITHWLWKEWpdwQVPESSEVMLKILRKIRAR------STPPVIHCSAGVGRSGTLMAVEIALQSI
... ..|.. . ..| |.. | .. .| . .|.| .. . || | | |. . | |..||.|||||||.. .. |. .
kyqdltvehslekeendyqiitlelkfknes.ahnvtlyyykkw...nintnnkpylkplfgilaknqlengnrPlvvacsdGvGrsGtflvidsqlera
HTHFTLpDIKQIVSHLRVtGRAASVQTLQQYMLIWKVLLDFgvA
| .. || . . ..| | . |.|...|. | ..| .. |
ktegvs.difdflrkirs.qriglvdtkeryiyihellaey..a
|
|||||||||
subfamily_Cele-PTP-3_pd | Subfamily Cele-PTP-3 | 289-395 | 1.8e-07 | 22.9 | In-house | 28-121 (275) | alignment | ||
Range on Protein: 289-395
Range on HMM: 28-121/275.0
VNNKKNRYSNIPCLDISrvqlkfkMPNKNSTDYIHANYIRSPFlkRGYILTQGPKKETRADFWRMIWQENTTAIVMLCQfletNREKCAEYFPRNAHCCL
| .|||..|. |.| . .| ..||| .|.|. ....| |. | ||. ...| | ..| | | . |..
rngeknrftnvtcfdei.......ldrenqeffvhantfrtpy..gnflisqapndstnadhlhllwiynvqtvvclvl....peeaggyfvpkegetft
QFDKFSV
|.|. .
sfqkyqi
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 290-519 | 2.4e-73 | 241.8 | Pfam-A | 1-234 (235) | alignment | ||
Range on Protein: 290-519
Range on HMM: 1-234/235.0
NNKKNRYSNIPCLDISRVQLkfkMPNKNSTDYIHANYIRSPFLKRGYILTQGPKKETRADFWRMIWQENTTAIVMLCQFLETNREKCAEYFPRNAHCCLQ
| |||||..|.. | .||.| .....|||.|||... |. .|.|||| |.| .|||||.|||....||||.. | .|||||.|.|.. . |.
nkkknRykdilpydktrvkl...kgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeeslt
FDKFSVNYE-DST-VNKSLVTTRLNLSYEGET---RLITHWLWKEWPDWQVPESSEVMLKILRKIRARS----TPPVIHCSAGVGRSGTLMAVEIALQSI
.....|... ... .|. ... |.|. ..| | .... ...|||..||||.. .|...||.. .. .| |.||||||||.||..|..|.|...
ygdikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldilleql
HTHFTlPDIKQIVSHLRvTGRAASVQTLQQYMLIWKVLL
... . .|..|||..|| . |. .||.|.||. . |..|
eaeee.vdvlqivkelR.kqRpgmvqsleqYiflykail
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 290-519 | 2.4e-73 | 241.8 | In-house | 1-234 (235) | alignment | ||
Range on Protein: 290-519
Range on HMM: 1-234/235.0
NNKKNRYSNIPCLDISRVQLkfkMPNKNSTDYIHANYIRSPFLKRGYILTQGPKKETRADFWRMIWQENTTAIVMLCQFLETNREKCAEYFPRNAHCCLQ
| |||||..|.. | .||.| .....|||.|||... |. .|.|||| |.| .|||||.|||....||||.. | .|||||.|.|.. . |.
nkkknRykdilpydktrvkl...kgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeeslt
FDKFSVNYE-DST-VNKSLVTTRLNLSYEGET---RLITHWLWKEWPDWQVPESSEVMLKILRKIRARS----TPPVIHCSAGVGRSGTLMAVEIALQSI
.....|... ... .|. ... |.|. ..| | .... ...|||..||||.. .|...||.. .. .| |.||||||||.||..|..|.|...
ygdikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldilleql
HTHFTlPDIKQIVSHLRvTGRAASVQTLQQYMLIWKVLL
... . .|..|||..|| . |. .||.|.||. . |..|
eaeee.vdvlqivkelR.kqRpgmvqsleqYiflykail
|
|||||||||
subfamily_egg_pd | Subfamily egg | 290-522 | 1.8e-43 | 143.4 | In-house | 40-270 (307) | alignment | ||
Range on Protein: 290-522
Range on HMM: 40-270/307.0
NNKKNRYSNIPCLDISRVQLKFKMpNKNSTDYIHANYIRSPFLKRGYILTQGPKKETRADFWRMIWQENTTAIVMLCQFLETnrEKCAEYFPRNAHCCLQ
| .| | ..| | |||.|... . . |.||||... | .||.| | |.| |||||..||. |||| |. |.| |.|. |.
nlekarskrvhckdssrvklelrr.GqylddfihanrvkGkpllnefilaqaplkntvddfwrmvfqeevqyivmltsrkes..erceyywpkaesdslv
FDKFSVNYEDSTVN----KSLVTTRLNL-SYEGETRLITHWLWkewpDWQVPESSEVMLKILRKIRARSTPPVIHCSAGVGRSGTLMAVEIALQSI-HTH
. |.. | |. . |.|.| . | | . || . |.. |..|||.| |.| |... || ...||.|.|||| |.
tvpGslrienlkvdskadplfrvtklklvGgddeerflehwqg....dvnnssdvysplrvlrklrnlskpvvvqdilGvskaatlvaieiallsllrGp
FTLPDIKQIVSHLRVTgRAASVQTLQQYMLIWKVLLDFG
| ... | || | ||.. .|.......| |
itkslvlravvflrlr.rrlsvesvllylfvyrlvlfff
|
|||||||||
0041856 | (Phosphotyrosine protein) phosphatases II | 290-520 | 3.7e-43 | 142.6 | In-house | 1-169 (182) | alignment | ||
Range on Protein: 290-520
Range on HMM: 1-169/182.0
NNKKNRYSNIPCLDISRvqlkfkmpnknSTDYIHANYIRSPFLKRGYILTQGPKKETRADFWRMIWQENTTAIVMLCqfletnrekCAEYFPrnahcclq
| .|||||.|.. | || |||.||...... . .|.|||| ..| |||.||..... |.||.|. . |.|
nldknrysdilpydhsr...........dldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlt.........eelywp........
fdkfsvnyedstvnkslvttrlnlsyEGETRLITHWLWKEWPDWQVPEsSEVMLKILRKIRARSTPPVIHCSAGVGRSGTLMAVEIALQSihtHFTLPDI
| ..||....|. |||. ||. . .|.......... | ..||||||||.||| | . .. ...|...
..........................ellerlgiqylylpwpDhgvpd.ldelldfieevleeggpvlVHCsaGvgRtgtlvaaylmkkl...gvsleea
KQIVSHLRvtgrAASVQTLQQYMLIWKVLLD
. | | .|.|..|| .. .||.
vklvrsrR....pgmvitpnqyfflqlalle
|
|||||||||
subfamily_Cele-PTP-19_pd | Subfamily Cele-PTP-19 | 290-530 | 5.4e-38 | 125.4 | In-house | 50-284 (301) | alignment | ||
Range on Protein: 290-530
Range on HMM: 50-284/301.0
NNKKNRYSNIPCLDISRVQLkfkMPNKNsTDYIHANYIRSPFLKRGYILTQGPKKETRADFWRMIWQENTTAIVMLCQFLETNREKCAEYFPRNAHCCLQ
...|.|| ..|| . |.. . . . ||||.| .. . .| |||| |.|. ||| |. | . ||||.|..| . |||.||.| . . |.
pkdkhryptvPckPstavev...ivdGk.rvPihanwiptsGhphrfiatqgPlkntsedfwamlvqydvekivmlgqkvekleekceeylpvkisekld
FDKFSVNYE--DSTVNKSLVTTRLNLS---YEGETRLITHWLWKEWPDWQVPESSEVMLKILRKIRARSTPPVIHCSAGVGRSGTLMAVEIALQSIHTHF
..|... . .. .||... .|.. . .|| .||. ..||.| .||.| . ... .. | |.|||||.||| .... |. . ....
igrfkikiknkelilnkkiskrtlevedstgkfatrtvthyqysewtdrgvPkshaelfdlmelvkksekPivvhcsaGiGrsvafigteylareveadp
TLpDIKQIVSHLRvTGRAASVQTLQQymLIWkvlLDFGVAYKQITE
|. .... . ||| | .||| .| | | . .| |. | |
ti.eltealkhlr.ehrwngvqtnsq..lyw...mtlGtvyrlike
|
|||||||||
subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 290-519 | 1.5e-37 | 124.1 | In-house | 3-236 (237) | alignment | ||
Range on Protein: 290-519
Range on HMM: 3-236/237.0
NNKKNRYSNIPCLDISRVQLKFKMPNknsTDYIHANYIRSP-FLKRGYILTQGPKKETRADFWRMIWQENTTAIVMLCQFLETNREKCAEYFPRNAHCcL
|. ||||.|| . | ||| || . .||| |.|... . || .||| . . |||.|.|||. . |||| ..| |..|| .|.|
nkiknrygnivaydhsrvvlkgagsg...sdyinatylkgfdgtpkkyiaaqgplesscddfwqmvwqekcsvivmltgliegnelkchkywpstdqp.a
QFDKFSV------NYEDSTVNKSLVTTRLNLSyegETRLITHWLWKEWPDWQVPESSEVMLKILRKIRAR------STPPVIHCSAGVGRSGTLMAVEIA
. ...| .. | || |...||.| | ||| . . ||| ||. . .|.. ..| | |.| .|||||||||.| .. ..
aygvltvslkkkeefsdytvrslllskrltlk...evrlihqyqftswpdrgvpqqtaallrfrkniinrsphvsesgpwiihcsagvgrtgiflvidam
LQSIHTHfTLPDIKQIVSHLRvTGRAASVQTLQQYMLIWKVLL
|. . . . || . | . | .|| .||..| ...|
lrqakek.kvvdiynyvysie.edrpyiiqtkdqyvfihqtil
|
|||||||||
subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 290-440 | 5.4e-29 | 96.0 | In-house | 33-184 (297) | alignment | ||
Range on Protein: 290-440
Range on HMM: 33-184/297.0
NNKKNRYSNIPCLDISRVQLKFKMPNKnstDYIHANYIRSPFLKR--GYILTQGPKKETRADFWRMIWQENTTAIVMLCQFLETNREKCAEYFPRNAHCC
.|||| .| | .||.|. .... ||| |.|. | . |||.||| ..| |||....... .|||.... | |.||| |.|.
slrknryrdilatddtrvkllrviter...dyinadyvvfpdeeadlkyilaqGplsatvddfwtlvaeqdvrvivmvaklqedGrdkcapywpsvvqer
LQFDKFSVNYEDSTV---NKSLVtTRLNLSYEGETRLITHWLWKEWPDWQVPESSE
|. .. |.. || .. . | |.| | |.| ..| . ||| || |
lkagdvvveflsstsdefdrvil.telqliyrsesrvvrhvqflswpdhGvpsdle
|
|||||||||
subfamily_Cele-PTP-12_pd | Subfamily Cele-PTP-12 | 290-375 | 4.5e-06 | 20.4 | In-house | 34-117 (332) | alignment | ||
Range on Protein: 290-375
Range on HMM: 34-117/332.0
NNKKNRYSNIPCLDISRVQLkfkMPNKNSTDYIHANYIRSPFLKRGYILTQGPKK-ETRADFWRMIWQENTTAIVMLCQFLETNREK
| || . |.| |||.| |. |. |... | ||..| | . | ||||. . . . |... . | .. |
nmdmnriphlycfdhsrvel...apqdgkddfynaswvdgyskksayifaqapfndhteyvfwrmvserkpsmilvfgdidekqkrk
|
|||||||||
subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 292-383 | 1.3e-17 | 58.6 | In-house | 49-153 (350) | alignment | ||
Range on Protein: 292-383
Range on HMM: 49-153/350.0
KKNRYSNIPCLDISRVQLK--FKMP-----NKNSTDYIHANYIRSP----FLKRG--YILTQGPKKETRADFWRMIWQENTTAIVMLCQFLETNREKCAE
||||.|| . |||.|| | . .. ||| |||.. . . . || ||.| ..| ||...| . . . |..| . | |.||| .
aknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvelnlekcyr
YFPRN
|...
YWqeg
|
|||||||||
subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 292-382 | 1.9e-08 | 28.1 | In-house | 50-155 (349) | alignment | ||
Range on Protein: 292-382
Range on HMM: 50-155/349.0
KKNRYSNIPCLDISRVQLKFKMPN----KNS---------TDYIHANYIRSPFLK--RGYILTQGPKKETRADFWRMIWQENTTAIVMLCQFLETNREKC
||||..| . |||.|| . . |.| ||| |||.. . .. . || || | | ||...| .. .. | . |.. |||
aknrykdilPyehsrvklkkslksskvikastsesdsgklddyinanylkltrisvekkyiatqaPlPstvddfykvillngvklvlsLnddkelslekc
AEYFPR
|.
diywqe
|
|||||||||
subfamily_Cele-PTP-1_pd | Subfamily Cele-PTP-1 | 293-540 | 2.8e-39 | 130.0 | In-house | 22-279 (290) | alignment | ||
Range on Protein: 293-540
Range on HMM: 22-279/290.0
KNRySNIPCLDISRVQLKfKMPNKNSTDYIHANYIRSPFLKRgYILTQGPKKET-------RADFWRMIWQENTTAIVMLCQFLETNRE----KCAEYFP
..| ..| . .|| || .. . ||||||.. | | |||| |.... .|| |. ||. . .||||.| | ... ||.|.|
dqR.levpLveatrvvLk.gygkrfnddyiHAnrvtcpnglr.liltqsPqekitekrnStiekfwwmakqEkvkqvVmlcefeeksantslfaCakYvp
RNAHCCLQFDKFSVNYEDSTVNKSLVTTRLNLSYEGETRL-ITHWLWKEWPDWQVPESSEVMLKILRKIRARSTPPVIHCSAGVGRSGTLMAVEIALQSI
.. |.|. ..|. . .. . | .| . ...| . .|| | |.| . .|.|.. ..|....|..|. || ..|| |. || .| |.... | |
esvgeelkfkgltvkCkskekeddvetRelvvkfddeeeftvtHsllkgWnklnvqedtktllsliqkvkasktpvivHcvdGiSrsAalaaiilgyQki
HTHFTLPDIKQIVSHLRVTgRAASVQTLQQYML-IWKVLLDFGVAYKQITEELAE-KFNSTY
...... || || ... ... . ..| . ...|..|| | | .. .
aetsgsvkledvlkalrkq.ralaitsalelafvdagivllaievldqfaeeetekkakaee
|
|||||||||
subfamily_eak_pd | Subfamily eak | 296-442 | 4.5e-16 | 53.1 | In-house | 58-201 (332) | alignment | ||
Range on Protein: 296-442
Range on HMM: 58-201/332.0
YSNIPcLDISRVQLKFKMpnKNSTDYIHANYIRSPFLKRGYILTQGPKKETRADFWRMIWQENTTAIVMLCQFLETNREKCAEYFPRNAHCCLQFDKFSV
. .| | |.| . .| || | . . . | |||| .... ||.|. .... |||.| . .| . || ||| ... |.| .. |
vkivp.ydrylvrltssq..lnrlGyinaslaefsevGrkyiltGiasedkvfafwqmvleqkspaivqlledvelkleksdkyfpdktreelkfGildv
NYEDStVNKSLV-TTRLNLSYEGETRLITHWLWKEWPDWQVPESSEVM
. . |... . | | || || . |. | . ..| . .
erkef.vkrniletrllelskGnethrvlhykvfGwtettlpkyedfl
|
|||||||||
0044763 | (Phosphotyrosine protein) phosphatases II | 310-514 | 1.6e-27 | 91.7 | In-house | 9-163 (178) | alignment | ||
Range on Protein: 310-514
Range on HMM: 9-163/178.0
KFKMPNKNSTDYIHANYIRsPFlkrgYILTQGPKketrADFWRMIWQENTTAIVMLCQFLETNREKCAEYFPRNAHcclqfdkfsvnyedstvnkslvtt
..... ...|||.|..| |. ..|.. | ||......... |.||.|.. || ...|| .|.|..|.
lsnleglersdyinaseil.pg....lylgslpp....addlellkelgithivnlteelelgflkcdpywpeeag........................
rlnlsyegetrliTHWLWKEWPDWQVPESSEVMLKILRKIR----ARSTPPVIHCSAGVGRSGTLMAVEIALQSihtHFTLPDIKQIVSHLRvtgrAaSV
..|. .||. ||...| .|.... |. . | ..||||||||||||.| . .. ...|... . | | |
.............iqylhipipDhgvpdllehflefvefieealdekggpvlVHCsaGvgRsgtlvaaylmkkl...glsleeaielvrerR....p.iv
QTLQQYMLI
.. |. .
pnpgqlrqL
|
|||||||||
0046846 | (Phosphotyrosine protein) phosphatases II | 316-517 | 2.9e-34 | 113.7 | In-house | 9-168 (176) | alignment | ||
Range on Protein: 316-517
Range on HMM: 9-168/176.0
KNSTDYIHANYIRSPFlkrgYILTQGPKKETRADFWRMIWQENTTAIVMLCQFLETNREKCAEYFPRNAHCCLqfdkfsvnyedstvnkslvttrlnlsy
.. |||.||.| ... .| |||| .| |||..|..... ||.|.|.. |..| ||. |.|. .
dldldyinanlilgsr....piatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpeleklgi...........................
egetrlitHWLWKEWPDWQVPESsEVMLKILRKIRARS---TPPVIHCSAGVGRSGTLMAVEIALQSihthfTLPDIKQIVSHLRVTGRAASVQTLQQYM
..|. ||| .||.. | .|..|. || . | ..|||||.||.||| | . . .. ......| . .||| .||
........qylhlpwpDhgvpdl.elllellefirealkeggpvlVHCsaGigRtgtlvaayllele.....kglsveealalvreqRplgavqtpeQyr
LIWKV
. ..
flyef
|
|||||||||
0043147 | (Phosphotyrosine protein) phosphatases II | 317-515 | 1.5e-36 | 121.1 | In-house | 3-154 (172) | alignment | ||
Range on Protein: 317-515
Range on HMM: 3-154/172.0
NSTDYIHANYIRSPFLKRGYILTQGPKKETRADFWRMIWQENTTAIVMLCQFletnrekcaeyfprnahcclqfdkfsvnyedstvnkslvttrlNLSYE
...|||.|.|. .. . .| |||| .| ||||||..... |.||.|... . .|
egsdyinasyldlyyipdrfiatqgplrntladfwrmlkelgithivnltel...........................................lydpe
GETRLITHWLWKEWPDWQVPeSSEVMLKILRKIRA-----RSTPPVIHCSAGVGRSGTLMAVEIALqsihTHFTLPDIKQIVSHLRvtgrAASVQTLQQY
...||. ..|. ||| || ..|..|..|. |. .. | ..||||||||.||| | . | ...| .. . | . | .||. .||
llerlgiqylylpwpDhgvp.llellleflefidellalspggpvlVHCsaGvgRtgtlvaaylml....lglsleeavalvrekR....pgavqnpsqy
MLIW
...
rfly
|
|||||||||
0051429 | (Phosphotyrosine protein) phosphatases II | 318-533 | 1.5e-37 | 125.1 | In-house | 3-236 (272) | alignment | ||
Range on Protein: 318-533
Range on HMM: 3-236/272.0
STDYIHANYIRSPFL---KRGYILTQGPKKETRADFWRMiWQENTTAIVMLCQFLETNREKCAEYFP----------RNAHCCLQFDKFSVNYEDSTVNK
..||.|... .. .. .....|| . | |||||. .... ..||.|.. | .|.|| | | ... . ...| . ..
lsgyiNardvggygrvvkpgrlyrsggplpltaadfwrl.kelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseelll
SLVTTRLNLS---YEGETRLITHWLWKEWPDWQVPESSevMLKILRKIRArSTPPVIHCSAGVGRSGTLMAVEIALQSIHTHFTLPD-------IKQIVS
. ..| |. . ||.| ..|... ||| ||... .|..|. ... . | ..|||||..|.||. |. . |. .. . . | . ..|.
dyilrellltlllsagearevmhlhytdwpdhgvpqea..llellellld.ggpvlvHCsaGkdRTGtvvallllllgvsletivddYlltnlyleeave
HLRVTGrAASVQTLQQYMLIWKVLLDFGVAYKQITEELA
.|| ...||| .||. ....||.. .. .. .|
elraqr.pgavqteeqylflyeallellrsllsvraeyl
|
|||||||||
0036282 | (Phosphotyrosine protein) phosphatases II | 319-515 | 1.8e-36 | 120.8 | In-house | 2-163 (174) | alignment | ||
Range on Protein: 319-515
Range on HMM: 2-163/174.0
TDYIHANYIRSPFLKRGYILTQGPKKetradFWRMIWQENTTAIVMLCQFLETNREKCAEYFPRnahcclqfdkfsvnyedstvnkslvttrlnlSYEGE
.|||.|... ...|..||| . ||.|..... |..|||.. | ...|| |.|. .| .
sdyinaspldlsyitprliagqgpla.....fwemlkelgittvvmlleekelglykcinywpe...............................lredl
TRLITHWLWKEWPDWQVPESSEvMLKILRKIRAR-----STPPVIHCSAGVGRSGTLMAVEIALQSIHthFTLPDIKQIVSHLRVTgRAASVQTLQQYML
.||. ..|. ||| .||..|. .|.... .. . | ..||||||||.|||.| . |. .. .| |. ..| || | .||| .||.
erlgiqylylpwpDhgvpdlsi.llefvkfveealsedpggpvlVHCsaGvgRtGtlvaaylmlrgll..eslvdaldlvrelRlq.rpgmvqtpsQyrf
IW
.
ly
|
|||||||||
0051082 | (Phosphotyrosine protein) phosphatases II | 319-518 | 1.6e-29 | 97.8 | In-house | 3-149 (151) | alignment | ||
Range on Protein: 319-518
Range on HMM: 3-149/151.0
TDYIHANYIRSPflkrgYILTQGPkketRADFWRMIWQENTTAIVMLCQFLETNreKCAEYFPRNAhcclqfdkfsvnyedstvnkslvttrlnlsyege
.|||...|. . .....|| |||........ ..||.|.. |.. .|.||.|..
sdyinfsyvtgg.....lyrsggp....ladflellkelgiktivnlrseeerg..ycpeylpelg..................................
tRLITHWLWKEWPDWQVPESSEVMLKILRKIRAR-STPPVIHCSAGVGRSGTLMAVEIALQSihthftlPDIKQIVSHLRVTGRaASVQTLQQYMLIWKV
. ..|. . ||| ..|.| . .|..|..... . | ..|||||.||.|||.|. . |. .. ......| . .||. ||.... ..
.ievlhipildwpdpglplsfdavleflellldkkngpvlvHCsaGkgRTGtlvalylmllg.......vsleealeeyrlkrp.gvvqpnqqflfqlfa
L
|
l
|
|||||||||
0049260 | (Phosphotyrosine protein) phosphatases II | 333-515 | 3.9e-31 | 103.2 | In-house | 8-143 (152) | alignment | ||
Range on Protein: 333-515
Range on HMM: 8-143/152.0
KRGYILTQGPKKETRADFWRMIWQENTTAIVMLCQFLETNREKCAEYFprnahcclqfdkfsvnyedstvnkslvttrlnlsyegetrlitHWLWKEWPD
.. .| |||| .| ||||||... . |.||||...|| ...||..|. ..|. |||
pfefiatqgpgpntladfwrmlkelgittivmltellelgklkceqyi...........................................qylhlpwpD
WQVPESSEVMLKILRKI----RARSTPPVIHCSAGVGRSGTLMAVEIALqsihTHFTLPDIKQIVSHLRvtgrAASVQTLQQYMLIW
||..|...| .|. | . .. | ..||||||||.|||.| . | ...| .. . | | .|.. .|....
hgvpdlsqlllflllfieklaldkggpvlVHCsaGvgRtgtlvaaylml....lgvsleeavalvrekR....pgavpnpgqlrfly
|
|||||||||
subfamily_Nvec-PTP-3_pd | Subfamily Nvec-PTP-3 | 333-517 | 1.2e-15 | 52.2 | In-house | 3-198 (198) | alignment | ||
Range on Protein: 333-517
Range on HMM: 3-198/198.0
KRGYILTQGPKKETRADFWRMIWQENTTAIVMLCQFLeTNRE-KCAEYFPRNAHCCLQFDKFSVNYEDSTVNKSLVTTRLNLS----YEGETRLITHWLW
.| || || | .|| ||||.|.|. . |||. . |.| . |.| . .. .|| . |.. . | | |. || |.|. .
qrryiatqhplretladfwqmvwetgsghivmvnddq.knkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyqf
KEWPDWQVPESSEVML------KILRKIR-ARSTPPVIHCSAGVGRSGTLMAVEIALQSIHT-HFTLPDIKQIVSHLRVtGRAASVQTLQQYMLIWKV
| . |. . . .. .| . .| ..||| | | .| ..|..| ..| . .. |. .. || | . .||.| .|..|
tswkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrq.arcgiisslqhynfiyqv
|
|||||||||
subfamily_Anemone-PTP-3_pd | Subfamily Anemone-PTP-3 | 333-517 | 1.3e-15 | 52.1 | In-house | 4-199 (199) | alignment | ||
Range on Protein: 333-517
Range on HMM: 4-199/199.0
KRGYILTQGPKKETRADFWRMIWQENTTAIVMLCQFLeTNRE-KCAEYFPRNAHCCLQFDKFSVNYEDSTVNKSLVTTRLNLS----YEGETRLITHWLW
.| || || | .|| ||||.|.|. . |||. . |.| . |.| . .. .|| . |.. . | | |. || |.|. .
qrryiatqhplretmadfwqmvwetgsghivmvnddq.knkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyqf
KEWPDWQVPESSEVML------KILRKIR-ARSTPPVIHCSAGVGRSGTLMAVEIALQSIHT-HFTLPDIKQIVSHLRVtGRAASVQTLQQYMLIWKV
| . |. . . .. .| . .| ..||| | | .| ..|..| ..| . .. |. .. || | . .||.| .|..|
tswkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrq.arcgiisslqhynfiyqv
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 333-434 | 1.6e-10 | 34.9 | In-house | 235-332 (440) | alignment | ||
Range on Protein: 333-434
Range on HMM: 235-332/440.0
KRGYILTQGPKKETRADFWRMIWQENTTAIVMLCQFletNREKCAEYFPRNAHCcLQFDKFSVNYEDSTVNKSLVTTRLNLSYEGETRLITHWLWKEWPD
| .| || | | ||||.. . . ..|.|| |. | |. |.| |. . | |.| . | . . |.| | | | . . ||
knafiatqmpldstvldfwrlvhdyristiimlnql...ndktcsiywpvntrs.vtfgpftvghkgsenmnrvkvrtlelkykeevheirqfevqtwpt
WQ
|
wi
|
|||||||||
subfamily_Cele-PTP-9_pd | Subfamily Cele-PTP-9 | 335-527 | 9e-29 | 95.3 | In-house | 36-226 (255) | alignment | ||
Range on Protein: 335-527
Range on HMM: 36-226/255.0
GYILtqgpkkeTRADFWRMIWQENTTAIVMLCQFLETNREKCAEYFPRNAHCCLQFDKFSVNYEDsTVNKSLVTTRLNLSYEG---ETRLITHWLWKEWP
|.| | . |...| | .|. .|||| | | ..||| .||| . |.. . .| . .... .. |. .|. | .|. ..|. .| |.
lysl.......tvdkfyqtivqtktevvvmlcdfaeegvekcssyfplekdeklkladvnvtttk.ssadvvlrtleitstlgekkkthtvkhysykGWi
DWQVPESSEVMLKILRKIRArSTPPVIHCSAGVGRSGTLMAVEIALQ----SIHTHFTLP-DIKQIVSHLRVTgRAASVQTLQQYMLIWKVLLDFGVAYK
. . || .. .|.||. .| | . |.|||.|.||| ... .|.. | |..| | | .... .|| . |.....| | . ..||. .
eknaPelareilnilkvvrd.sksvvvhCstGiGrsaafvlaelvyqkmirsldttetveldylslleelrsk.rkraihtPlqlafsilmvldlvfpkg
Q
.
e
|
|||||||||
subfamily_Cele-PTP-7_pd | Subfamily Cele-PTP-7 | 341-514 | 2.4e-24 | 80.3 | In-house | 98-280 (302) | alignment | ||
Range on Protein: 341-514
Range on HMM: 98-280/302.0
GPKKETRADFWRMIWQENTTAIVMLCQFLETNREKCAEYFPRNAHCCLQFDKFSVNYE-------DSTVNKSLVTTRLNLSYE----GETRLITHWLWKE
|||.|. .| .| | |.. .| ||.| | . .|||||. . |.| ...|. . | ||.. ... | . . ..
vpkkstlekhwalieqynvaivvqlcsfvedeekkcaeyysdkvggelkfgrytvktvsvktdleeftdkksfklytveiknekkkkkvkktvdilafsa
WPDWQVPESSEVMLKILRKIRARSTPPVIHCSAGVGRSGTLMAVEIALQSIHTHfTLPDIKQIVSHLRVtGRAASVQTLQQYMLI
||| |. .. |.||. . . ..||||||||.|||.|. .| .. |. .|| .| | .||. || . .
wpdhGapkeaytaldilkfcesykknvlvhcsaGvGrtGtlvaikyGiqlcskk.kvtdllsivlpvrq.cryGavqdeqqliyl
|
|||||||||
subfamily_hpo-7_pd | Subfamily hpo-7 | 346-522 | 3.4e-24 | 80.1 | In-house | 46-227 (263) | alignment | ||
Range on Protein: 346-522
Range on HMM: 46-227/263.0
TRADFWRMIWQENTTAIVMLCQFLETNREKCAEYFPRNAHCCLQFDKFSVNYEDSTVnKSLVTTRLNLSYEG---ETRLITHWLWKEWPDWQVPESSEVM
| . |...| | .|. .|||| | | ..||| .||| . ... . .| .. . |. |. ||. | .|. ..|. .| |.. . || .. .
tidkfyqtivqtktevvvmLcDfneegvekcssyfPlekdekqklanvnvcttkvqs.dvllktlellstlgeKkkthtvkhysykgWiekndpelarei
LKILRKIRaRSTPPVIHCSAGVGRSGTLMAVEIALQ----SIHTHFTLP-DIKQIVSHLRVTgRAASVQTLQQYMLIWKVLLDFG
|.||. | | . |.|||.|.||| .|.. | |..| | | ... .|| . |.....| | ..|||
lnilkvar.nskslvvhcstGiGrsaafsvaElvyqkmirsldttstveldylsLleelrss.rkraihtPmqLafsilmvLdfv
|
|||||||||
0048179 | (Phosphotyrosine protein) phosphatases II | 407-514 | 5.3e-17 | 57.3 | In-house | 34-137 (144) | alignment | ||
Range on Protein: 407-514
Range on HMM: 34-137/144.0
VTTRLNLSYEGETRLITHWLWKEWPDWQVPESSEVMLKILRKIRAR---STPPVIHCSAGVGRSGTLMAVEIALqsiHTHFTLPDIKQIVshlRVtGRAA
.. . . .| ..| ....|. |||..||...| .|..|. |.. . | ..||||||||.|||.| . . . ...| .. . | | |
inlteeyepefleregiqylhlpwpDhgvpdllellleflefieealeeggpvlVHCsaGvgRtgtlvaaylmk...klglsleealalv...rs.rrpg
SVQTLQQYMLI
.|.. .|.. .
avpnpgqlrfL
|
|||||||||
0048076 | (Phosphotyrosine protein) phosphatases II | 408-517 | 1.7e-17 | 58.9 | In-house | 31-138 (145) | alignment | ||
Range on Protein: 408-517
Range on HMM: 31-138/145.0
TTRLNLSYE--GETRLITHWLWKEWPDWQVPESSEVMLKILRKIRAR---STPPVIHCSAGVGRSGTLMAVEIALQsihTHFTLPDIKQIVSHLRvtgrA
|| |||..| ...||....|. |||..||...| .|..|. |.. | ..||||||||.|||.| . |. ...|... . | |
ttvlnltselellerlgiqylylpwpDhgvpdllellleflefieealkeggpvlVHCsaGvgRtgtlvaaylmll...lgvsleealelvrsqr....p
ASVQTLQQYMLIWKV
.|.. .|. . ..
gavpnpgqlrflyef
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 412-520 | 8.8e-10 | 32.5 | In-house | 79-192 (440) | alignment | ||
Range on Protein: 412-520
Range on HMM: 79-192/440.0
NLSYEG--ETRLITHWLWKEWPDWQVPESSEVMLKILRKI-----RARSTPPVIHCSAGVGRSGTLMAVEIALQSIHTHFTLpDIKQIVSHLRVtGRAAS
| || |.| . .. .. ||| ||. . .||... . .| . | ..|||||.||.| ..||. |. . . || ... .| |
nasyingiesrtlkqyhyqgwpdkgvpkfagpvlkmiqdvnesqekagngpllvhcsagagrtgviiavdsilreakrsdqi.difsfinsmrn.nrpqm
VQTLQQYMLIWKVLLD
||| .|| .. ...|.
vqtpeqyafvheavle
|
|||||||||
PTPc_DSPc_SM00012 | 422-519 | 1.7e-24 | 81.4 | In-house | 2-104 (105) | alignment | |||
Range on Protein: 422-519
Range on HMM: 2-104/105.0
ITHWLWKEWPDWQVPESSEVMLKILRKIRARST------PPVIHCSAGVGRSGTLMAVEIALQSIHTHFTLPDIKQIVSHLRvTGRAASVQTLQQYMLIW
..| ...||| .|||.|. .|..||... . | |.||||||||.||..|..|.||..... . .||.|||..|| . |. .|||..||. .
vkhyhytgwpdhgvPeesdsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelr.kqRpgmvqteeqylfly
KVLL
..||
rall
|
|||||||||
0038934 | (Phosphotyrosine protein) phosphatases II | 423-473 | 9.6e-06 | 20.9 | In-house | 80-135 (194) | alignment | ||
Range on Protein: 423-473
Range on HMM: 80-135/194.0
THWLWKEWPDWQVPESSEVMLKILRKIR-----ARSTPPVIHCSAGVGRSGTLMAV
..| .|| .. | |..|..|. . . ..|| ||.||.||| |
ieylklpfpddgtvPsleillrfldlvdeflnedpggvvaVHCkaGlgRtGtlvaa
|
|||||||||
subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 444-519 | 5e-14 | 46.8 | In-house | 219-292 (297) | alignment | ||
Range on Protein: 444-519
Range on HMM: 219-292/297.0
KILRKIRARSTPPVIHCSAGVGRSGTLMAVEIaLQSIHTHFTLPDIKQIVSHLRvTGRAASVQTLQQYMLIWKVLL
. || |... ..|||||||||| .. .. . .. . .||.. |.|.|| || ||||.|. |.... |
eslraemprnayllvhcsaGvGrsGvvvlsdv.ilaklrkkripdvaailsilr.eqrarlvqtleqfellydavl
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 451-522 | 2.8e-15 | 50.8 | In-house | 245-315 (319) | alignment | ||
Range on Protein: 451-522
Range on HMM: 245-315/319.0
ARSTPPVIHCSAGVGRSGTLMAVEIALQSIHTHFTLPDIKQIVSHLRvTGRAASVQTLQQYMLIWKVLLDFG
. | |.||| ||||.|...| .||..|. . || |.||..| .|| .|.| .|| .|.||| .
esqGPlvvhcsdGvGrtGlviasdiairsleeskrsvdiPqlvssvr.rdrasavltkeqyefiykvlseya
|
|||||||||
subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 451-521 | 3.3e-08 | 27.7 | In-house | 260-343 (350) | alignment | ||
Range on Protein: 451-521
Range on HMM: 260-343/350.0
ARSTPPVIHCSAGVGRSGTLMAVEIALQ------SIHTHFT--------LPDIKQIVSHLRvTGRAASVQTLQQYMLIWKVLLDF
|||.| ..|||||||| |||.... |. . ... |..|| .|| | ||.|.|.. |.. || .
arsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaaktrDlisiivnelr.kqrismvqnldqfifiYeallfy
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subfamily_Sponge-PTP7_pd | Subfamily Sponge-PTP7 | 457-518 | 8.1e-06 | 20.1 | In-house | 1-60 (69) | alignment | ||
Range on Protein: 457-518
Range on HMM: 1-60/69.0
VIHCSAGVGRSGTLMAVEIALQSIHTHfTLPDIKQIVSHLRVtGRAASVQTLQQYMLIWKVL
|.|||.| ||.||..|. . . | . | || | ..| | | .||.| |
vvhcssGtGrtGtfiaimvemarikse.klvdifnnvqymrk.crpmmvmneneymfihdal
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