Gene mtm-5 in Caenorhabditis elegans

Synonym: CELE_H28G03.6, mtm-5

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family Myotubularin
Subfamily MTMR5
Protein sequence
ID Type Fasta BLAST phosphatome Note
CeleP131_AA protein Get Run
CeleP131_AA_992-1452 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
uDENN uDENN domain 43-90 6.8e-06 15.4 Pfam-A 15-63 (65) alignment 
Range on Protein: 43-90
Range on HMM: 15-63/65.0
SDNIPTSSIKKFARPRGWYNQSVS-SPSEFFYQILTTERGTRRIAYVLS
.|. .   | .|. |.|.   . .  ..|||  .|| | |.|. .. | 
edeplpkaipmFCfPeglnfvtsreqkpeffsfvLTdedgsriyGfClr
DENN DENN (AEX-3) domain 104-270 4.8e-30 94.1 Pfam-A 4-175 (185) alignment 
Range on Protein: 104-270
Range on HMM: 4-175/185.0
VSIVLISQNFHPKAFKEILLEISNDLRTPEFSSSSELIRFLTYE--LVEEGSTIEI--RTKTLHVELGFELIPISPVTGKDVAMLFKMLGFQNVIKIIHA
 .....|.  . ..||.|| .. . |.. .  .  ..|. | .|  | ..|.|...   ... .. | .      |... |. .||..|. .||.... |
kalcilsrlpffelfkkiLkalekrlksssklplesfianlllevplPapgktlklkslsvkekillqrpssselPledvdleelfrcLsienvlqlfea

LLSDCRIVLASSSLMRLSRCQNAILSLLYPFEYVHSCVTILPDSLAEVLESPTPFLIGVLSEFVT-SFGDEN
.|.. ||.| |..| ||. . .|...||||... |  . .|| ||..|||.||||.||| |.. .    ...
vLlErriillSeklarLtsvaealvallyPlkWqhiyiPvlpaslldvleaPtPfiiGvesslleleekple
dDENN dDENN domain 331-405 1.6e-08 23.8 Pfam-A 1-68 (68) alignment 
Range on Protein: 331-405
Range on HMM: 1-68/68.0
LDKKLRACFIYYFAELLYGYQYYILYTRIKGNfekklttsLTFHVGAFRGFRKLT-DMMSSSLLKSVYFQTFILTR
||. .|..|  .||.||.||. .. . | .           .|.  ||.  |. .   . |..|.. .|..|| .|
ldqqvreaFlrffasllggYrnflrkerkspe........vsFqkeaFlksrskshrsFlsqfletqmFaeFieer
SBF2 Myotubularin protein 502-709 8.1e-73 233.7 Pfam-A 2-224 (225) alignment 
Range on Protein: 502-709
Range on HMM: 2-224/225.0
MLPVVNTHAEYHANQFEAYAHRIEALRNCLAAIFEGKVAFASKSLDAVKSSMRFAPLRIELCRLLNQKCSHDK--LTDKQFEDIALLMNAALQAECEEDK
. | |... |......| .|.|.|.||||.. ||. |...|.|||.|| ...... .|..||. |.... ...  |...||. .. |||.||| ....|.
agptvasivektkstvensarrlEvlrnCisyiFdnkileakKslpAvlralkskaaRlalceelekhvqqnravLdhqqFDlvvrlmNkaLqddsakde

DGVVRSLMYLSNVYSRKVAQGMQQYMYTAVQEHKVWKNQRFWTSCFYYEVHEMLFSEML-----QKDRKITESLWCHTLRPCAMEMI--------NTDDT
.||.. |..|| ...||...|..|..|| ||.|.|||||.||...||.||........|     .|..| ||| .... ...|.|..        .....
ygvaaallplssafcRKLsegvsqfaYtcvqdHpvWknqqFWeatfyqevqkaikelylekkseskkkkktesslskkeeksaleiaadqlrkwptlske

DQEELVKQENEMIQAQAKHFANI
.|.||||.|......||.|||| 
kqkelvkkeestvysqaihfanr
GRAM GRAM domain 787-871 3.9e-18 56.1 Pfam-A 4-68 (69) alignment 
Range on Protein: 787-871
Range on HMM: 4-68/69.0
KGNFDpvLAHGEFLISDpIDCYLLTSieesemslnrlenLLPADGSLFLTNYRVIFKGKSVDINAtngtIVQTIPLYSMESFKKL
. .|.  |...|.|..| ..||| ||             ..|..| |.|||||.||.....| ..    .|..|||.......| 
rktfk..lppeEklldd.yaCylsts.............kgpvqGrlYlTnyrliFrSdklddsk....vvvvipladikrveks
subfamily_Dicty-MTMR1-like_pd Subfamily Dicty-MTMR1-like 984-1424 6.4e-53 172.4 In-house 3-367 (404) alignment 
Range on Protein: 984-1424
Range on HMM: 3-367/404.0
FDKMEELDYLKKNAHIRYAVIDYPRIGLNSKIvKLRMSHSNLDYTICPSYPGNFIVPSETNESELAKVAKGFVEHRLPVVVWMNE-NGALLVRASAFT--
|.. |.  .|..   |  |  .| |.|..|.  . |.|. | ||..|..||  ..||.. ...|| |||.   . |.||..| .. ... ..|.|  .  
fsysekksvledgwliydaeeEykRlgikses.eWriskinsdyelcetYPkllvvPesisDeelkkvasfRskgRiPvlswrhrsknstitRssqplvG

-SIDMVKKLKKVVNYRRNASKLTGSMTGSQQTLHSKASSNEESSSNIVAGAEIKSAEVQ---MNYIAKLSNSSQRAVSYAlpTQYADKfstfndgctltq
 . .  ..  |..|  | |.. . ..   ..  . .|..|......     . . .|..   .. | .| .| ..    .  ..  .|            
ltksrseedEklinsirkaktqletlyildarpkanavansakgagyedisryenceieflnienihelreslkklkkav..nsiiek............

nnangfpttrihrkalyvllekghgvkipidsnaeaimvrsvkeselrrslqrarqicssefqvenRTSFLESWNASNWPQCVSRMIELSNSIVALMNLY
                                                                  .. .|.  . |.| . .....| |..|| |.. .
..................................................................eknwlselessrWldhiklllegskrivelieke

NSSVAICLEAGRSITTILSSLSQLLSDPYYRTCDGFQVLVEKEWLAFGHYFHKD--------TETSSPSFICFLDCVYQISQQYPTAFEFSYFYISFLAY
.||| .    |   |. |||||||| ||||||  ||.||.||||| ||| |..         ..  || |. |.|||||. .|.|| |||.  ... . .
kssvlvhcsdgwDrtsqlsslsqllldpyyrtiegFivliekewlsfGhkfaqRigqttekssdersPiflqFidcvyqltkqfptsFeFnekflikild

HSTAGYFRTFIDDCEEKRLQSDANEfylpdnlATINVWEFIKLRNrvsAAFYNELY
.. .. | ||. |.|..| |.. ..        |. .|  ..  .     . |.||
alyscrfgtFLydsekeRqqnnlak.......etvslWalleank...seylnply
0040695 (Phosphotyrosine protein) phosphatases II 993-1450 3.8e-97 319.3 In-house 4-385 (388) alignment 
Range on Protein: 993-1450
Range on HMM: 4-385/388.0
LKKNAHIRYAVIDYPRIGLNSKivKLRMSHSNLDYTICPSYPGNFIVPSETNESELAKVAKGFVEHRLPVVVWMNE-NGALLVRASAFTSidmvkklkkv
|... .... . .. |.||. .    |.|. | .|..|||||. ..||.. ....|..||. .  .|.||.....  |||.|.| | ...          
leegwslydilrelkrlglgld..lwrisivNenyelcpsYPallvVPksisdellkrvarfrskgriPvlsyrhpnngavllRssqplv..........

vnyrrnaskltgsmtgsqqtlhskassneesssnIVAGAEIKSAEVQMNYIAKLSNssqravsyalptqyadkfstfndgctltQNNANGFPTTRIHRKA
                                   ... .... |  ...| || .                            ... . .  .| . .|
..................................glllsrsledeklleailkllp............................nlskllivdlrpklna

LYVLLEKGHGVKIPIDSNAEAIMVRSVKESELRRSLQRARQICsseFQVENRTSFLESWNASNWPQCVSRMIELSNSIVALMNLYNSSVAICLEAGRSIT
|. .. .|.  ..   .||| |..   . . .|.|||. ...|   ..|.. ...| ... |.| .......||.  || |..| |||| .. . |...|
lanralgggvenedaypnaeliflnipnihvvreslqklldac...lnvpdslnllslleesgwldliklilelavlivklldlgnssvlvhcsdgwdrt

TILSSLSQLLSDPYYRTCDGFQVLVEKEWLAFGHYF---------HKDTETSSPSFICFLDCVYQISQQYPTAFEFSYFYISFLAYHSTAGYFRTFIDDC
..||||.||| ||||||..|||||.|||||.|||.|         ..|..  || |..|||||.|. .|.||||||..... |||.|.....|.||. ..
sqlssLaqllldPyYRTleGFqvLiekeWlsfghkfadRlghleseidskefsPvFllFLdcvwqLlrqfPtaFeFnerlLlfLadhlyscrfgtFlfns

EEKRLQSDAnefylpdNLATINVWEFIKLRNRVsaaFYNELYEQIGD-IVIPSSSIPQIHMWPFLAETH
| .||...        .  |...|.... |...   |.| ||..  . . .||.|......|  .  ..
ekerlelsv.......sertlslwsyllsrkse...flnplYdpsslevllpslsvldlllWleyylrw
Myotub-related Myotubularin-like phosphatase domain 994-1388 9.6e-98 320.2 Pfam-A 18-352 (353) alignment
Myotub-related Myotubularin-like phosphatase domain 994-1388 9.6e-98 320.2 In-house 18-352 (353) alignment
subfamily_MTMR5_pd Subfamily MTMR5 995-1451 2.2e-177 582.7 In-house 3-483 (483) alignment 
Range on Protein: 995-1451
Range on HMM: 3-483/483.0
KNAHIRYAVIDYPRIGLN-----SKIVKLRMSHSNLDYTICPSYPGNFIVPSETNESELAKVAKGFVEHRLPVVVWMNE-NGALLVRASAFTSIDMVKKL
.....|..|.|| |.||.     ||..|.|.|..| .||.| |||....||||......|.||| | ..|||||.|..| |.|||.|...|.|...|..|
eklaerayvqdykRlGlgalngaskrgkfrisevNkkytvcrsYPalivvPsevsddsiarvakcfrqnRlPvvtWrhernkalLiRsggfeskgvvgll

KKVVNYRRNASKLTGSMTGSQQTLHSKASSNEESSSNIVAGAeiKSAEVQMNYIAKLSNSSQRAV----SYALPTQYADKFSTFNDGCTLTQNNANGFPT
|.........|. ..|.....|. ..||..||.|.....|..  .|.||.....|. |.|..||.    ..|| ....||.|....|.||..|||. ...
ksantqgsstsessessksleqekylkavvnevsklsalaln..sslevslsvlasssssdkraalsteknaldisksdkasqggkgatlkennakeskk

TRIHRKALYVLLEKGH--GVKIPIDSNAEAIMVRSVKESELRRSLQRARQICSSEFQVENRTS--FLESWNASNWPQCVSRMIELSNSIVALMNLYNSSV
.|....|||||.||..  .||...||.||.|.|..|.......|.......|.....||...|  ||.|...|.| |..|....||...|.|..|..|||
lrarkaaLYvlgeksqlknvksevdskaefipvelveirqvkasfkkllraClpstaveeaesqsFlksvedseWlqqissllqlsgavvdlldlqgssv

AICLEAGRSITTILSSLSQLLSDPYYRTCDGFQVLVEKEWLAFGHYFHKDTE--------TSSPSFICFLDCVYQISQQYPTAFEFSYFYISFLAYHSTA
...||.|...|...|||.|||.||||||..||.||||||||||||.|.|...        ...|.|..|||||.|.|.|.|.||||..||..||||||..
lvslEdGwdvtaqvsslaqllldpyYRtleGFkvLveKEWLafGHrFtkrsnqtlsaqssgfaPvFlqFLDcvhqvsrqfPlafefndfylkflayhsvs

GYFRTFIDDCEEKRLQSDA---NEFYLPDNLATINVWEFIKLRNRVSAAFYNELYEQIGDIVI-PSSSIPQIHMWPFLAETHL
 .||||. |.|..||.|..   .... ... |...||..|. ....|..|||.||... ..|. |||.......|....|..|
nrfrtfllDseyerlesgllyeekaekrakkagksvwdyidrqhkrspifynflyspdesevlrPssnvsslkvWdyyleeel
subfamily_MTMR3_pd Subfamily MTMR3 1002-1078 1.8e-14 46.3 In-house 29-105 (442) alignment 
Range on Protein: 1002-1078
Range on HMM: 29-105/442.0
AVIDYPRIGLNSKiVKLRMSHSNLDYTICPSYPGNFIVPSETNESELAKVAKGFVEHRLPVVVWM-NENGALLVRASA
  ... |.|.. |  . |.|. | |. .|.||| ..|||.. ....|.|||.    .|||.|||  ..|||.|.|.| 
lkeeverlGfdlk.eawrisdvnsdfklCssyPkklivPksitdddlkkvasfrslkrlPavvwrhkkngavlarcsq
subfamily_MTMR9_pd Subfamily MTMR9 1003-1124 5e-14 44.2 In-house 29-139 (393) alignment 
Range on Protein: 1003-1124
Range on HMM: 29-139/393.0
VidypriglnsKIVKLRMSHSNLDYTICPSYPGNFIVPSETNESELAKVAKgFVEH-RLPVVVWMN-ENGALLVRASAFTSIDMVKKLKKVVNYrrNASK
.             . |.|. | ....|.||| ..|||   .. || ..|. |.|. |.||  ... |..| |.|.|   ..   |. |.  .     ..
s..........asdewRissvNknfkvcasypesvivPkaiddeelkasaa.freggrfPvLsylhketkavllrssqplcgssgkrckedekl..lnlv

LTGSMTGSQQTLHSKASSNEESSS
|. .  |.    .|| ......| 
lkklkkGlivdtrsksaaenarsk
subfamily_MTMR6_pd Subfamily MTMR6 1003-1077 6.5e-07 20.9 In-house 25-98 (397) alignment 
Range on Protein: 1003-1077
Range on HMM: 25-98/397.0
VIDYPRIGLNSKivKLRMSHSNLDYTICPSYPGNFIVPSETNESELAKVAKGFVEHRLPVVVWMN-ENGALLVRAS
  .| |.|. ..  |  ... | ||..| .|| .. ||...... |   .|    .||||. ..  || | . |.|
kaeytrmgvpne..kwtltdlnkdyelcdtyprelyvPksatkevlvgsskfrskgrlPvlsylhkeneaaicrcs
subfamily_MTMR1_pd Subfamily MTMR1 1004-1090 3.9e-13 41.4 In-house 14-100 (389) alignment 
Range on Protein: 1004-1090
Range on HMM: 14-100/389.0
IDYPRIGLNSKIvKLRMSHSNLDYTICPSYPGNFIVPSETNESELAKVAKGFVEHRLPVVVWMNEN-GALLVRASAFTSIDMVKKLKK
 .. | || ..  . |... | .|..|..||  ..||. .....| |||.   ..||||..|.|.. .| ..|||. ..  . |. |.
aelerlgllnek.lWritklnkkyelcdtYpavlvvpkvvsdedlkkvaafrskgRlPvlswlnkenqavilrasqplvGlsgkrske
subfamily_MTMR10_pd Subfamily MTMR10 1017-1086 4.6e-07 20.9 In-house 25-96 (380) alignment 
Range on Protein: 1017-1086
Range on HMM: 25-96/380.0
KLRMSHSNLDYTICPSYPGNFIVPSETNESELAKVAKGFVEHRLPVVVWMNENGALLVRASAFTSIDM--VK
. ...  |   . ....|  |.||   ..|.. .. . . | | |. ||   .|| |.| ||.   .    .
aivvllknelfaaaqtlPqyfvvpnslsdsdverlsrhykesRfplwvwshakgaallrlsalqeaesadke
subfamily_MTMR1_pd Subfamily MTMR1 1211-1443 1.4e-45 148.3 In-house 149-379 (389) alignment 
Range on Protein: 1211-1443
Range on HMM: 149-379/389.0
EAIMVRSVKESELRRSLQRARQICSSEFQvenRTSFLESWNASNWPQCVSRMIELSNSIVALMNLYNSSVAICLEAGRSITTILSSLSQLLSDPYYRTCD
| | .   .   .| ||.. .... .. .    ...| . ....| . .. ... .  ||  ..  ..|| .. . |   |. | ||..|| |.|||| .
elifldihnihvvReslkklkelvlpnvd...dkkwlsalestkWlehiklilagavkivekvetektsvlvhcsdGWDRtaqltsLamlllDsyyRtie

GFQVLVEKEWLAFGHYFHKD---------TETSSPSFICFLDCVYQISQQYPTAFEFSYFYISFLAYHSTAGYFRTFIDDCEEKRLQSDANEfylpdnlA
||.||.|||||.||| |..          ..  || |. |.|||.|...|.||||||   .. .|. |. ...| ||. ..|..| ... .|        
GfevliekeWlsfGHkfkeRlghgdknssdaersPvFlqfiDcvwqltrqfptAFefneefLitlldhlysclfGtflfnsekervkekvke.......k

TINVWEFIklrNRVSAAFYNELYEQI--GDIVIPSSSIPQIHMW
|. .| ..   |     | |.||..    ....|  |. ....|
tvslwsyv...nsskeeftnplyaeelekkvlypkaslrrlelW
subfamily_MTMR9_pd Subfamily MTMR9 1221-1444 2e-40 131.1 In-house 163-386 (393) alignment 
Range on Protein: 1221-1444
Range on HMM: 163-386/393.0
SELRRSLQRARQICSSefQVENRTSFLESWNASNWPQCVSRMIELSNSIVALMNLYNSSVAICLEAGRSITTILSSLSQLLSDPYYRTCDGFQVLVEKEW
...  ||..  . ||   .  .  .||.  ..|.| . |  ..|... .. ...  ...| .  |.|  .| ...||.||. ||..|| .||. |.|.||
asiqdslaklleacsd..aglstdkflsrleksgwlsqvadlleaalvvaqcldeegapvvvhgeeGlDatlqvtsLaqlildpdaRtvrgfealiereW

LAFGHYFHK----------DTETSSPSFICFLDCVYQISQQYPTAFEFSYFYISFLAYHSTAGYFRTFIDDCEEKRLQSDANEfylpdnlATINVWEFIk
.  || | .           ...|.| |. |||||||| .|.| .|||.  .. .|  || .  | ||. |.|..| . . ..        |...|... 
iqaGHPFasRaskvaaketkkklsgpvfllFLDcvyqilsqfpasFEFneelLillfehsyssqfgtflcdneaerkelklkk.......ktvslwsyv.

LRNRVSAAFYNELYEQIGDIVIPSSSIPQIHMWP
 |. .   | | |||.  ....||   . ...| 
nrpeklkqflnplyeanaeviwpsvapqslelWs
subfamily_MTMR10_pd Subfamily MTMR10 1221-1397 2.5e-36 117.3 In-house 127-315 (380) alignment 
Range on Protein: 1221-1397
Range on HMM: 127-315/380.0
SELRRSLQRARQICSSEFQV---ENRTSFLESWNASNWPQCVSRMIELSNSIVALMNLYNSSVAICLEAGRSITTILSSLSQLLSDPYYRTCDGFQVLVE
... .. .. |..|  .      .    .| | . ..| . |. .....  .|...   . || .  . || .  ...||.||..||.||| .||| |..
qdvqkaylklreLcvidtseefvtlddkwlssLektrWLayvrlclstasdavktvvekkrsvilqesegrDlscvvaSLaqlmldphyrtisGfqsliq

KEWLAFGHYFHK-------DTETSSPSFICFLDCVYQISQQYPTAFEFSYFYISFLAYHSTAGYFRTFIDDCEEKRLQS--DANEFYLP
||| | || | .       . ...|| |. |||||.|  .|.|..|||.  .   |  .| .| | ||  ..||.||.   . . ....
kewvaaghpfldrlghikpseksespvfllFldcvdqlleqfpseFeFtetfLialwdsshsgifltflfnseeqrlkavvssspllia
subfamily_MTMR3_pd Subfamily MTMR3 1223-1443 3.7e-40 131.0 In-house 218-435 (442) alignment 
Range on Protein: 1223-1443
Range on HMM: 218-435/442.0
LRRSLQRARQICSsefQVENRTSFLESWNASNWPQCVSRMIELSNSIVALMNLYNSSVAICLEAGRSITTILSSLSQLLSDPYYRTCDGFQVLVEKEWLA
.|.|..  |...|   | .... .| . .. .| | .| ... . ..|  ..  . .| .    |   || . .|..|| |||||| .||.||||.|||.
vrksfnslralls...qspdesnwlsalektkWlqnlsvllkaavkvveavdkegrpvlvhCsdGWdrttqivalakllldpyyrtleGfkvlvereWld

FGHYFH-----K----DTETSSPSFICFLDCVYQISQQYPTAFEFSYFYISFLAYHSTAGYFRTFIDDCEEKRLQSDANEfylpdnlATINVWEFIKLRN
||| |      .    |..  .| |. .||.|.|...|.||.|||.  ..  |. |. .. | ||. ..|..| ..  .|        |..||.... ..
fGhkfadrcghgenvddanercPvflqwldavhqlqrqfPtsfefneaflvklvqhtysclfGtflansekereeekvke.......rtlsvWsllrake

RvsaAFYNELYEQ-IGDIVIPSSSIPQIHMW
.   .. | ||..    ...|. |. ....|
k...eyrnllykekteavllpavsvrelklw
subfamily_MTMR6_pd Subfamily MTMR6 1223-1444 7.6e-33 106.3 In-house 171-389 (397) alignment 
Range on Protein: 1223-1444
Range on HMM: 171-389/397.0
LRRSLQRARQICSSEfqVENRTSFLESWNASNWPQCVSRMIELSNSIVALMNLYNSSVAICLEAGRSITTILSSLSQLLSDPYYRTCDGFQVLVEKEWLA
.| |||.  ...  .   .. ..||.. ..|.| . .  ... |  |   ..  . || .    |   |.   ||..|| |||||| .||.||.|||||.
mreslqkllevvelk..sksvseflsglessgwlkhikavldasifiakavaeegasvlvhcsdGwdrtaqvcslasllldpyyrtikGflvliekewls

FGHYFH-------KDTETSSPSFICFLDCVYQISQQYPTAFEFSYFYISFLAYHSTAGYFRTFIDDCEEKRLQSDANEfylpdnlATINVWEFIKLRNrv
||| |.       .|.   || |  ||.||.|. .|.|.||||.  ..  |  |  .  | ||. .||..| .   .|        |  .| ... |.  
fGhkfsercGlldedskevsPiftqflecvwqlleqfpkafefnerfllelhdhvyscqfGtflgncekdrrdlklke.......rtkslwayllerk..

sAAFYNELYEQIGD--IVIPSSSIPQIHMWP
 . . | ||..  .  .. |. .  ....| 
.ddylnplykaetekevlkpdtapaalklwr
subfamily_pats1_pd Subfamily pats1 1247-1329 8.8e-15 46.1 In-house 370-455 (691) alignment 
Range on Protein: 1247-1329
Range on HMM: 370-455/691.0
LESWNASNWPQCVSRMIELSNSIVALMNLYNSSVAICLEAGRSITTIL---SSLSQLLSDPYYRTCDGFQVLVEKEWLAFGHYFHK
 ..   | |   |  ..| .  .  |..  .| .      .  |.  |   |||.|.||||.||| |||.||.||||| .|. | |
wkeieeskwvdsvkllleaavkvsnlldeGssvllknsidsPlieldlasisslaqvlsdPfyrtldGfkvliekewlsyGfPfsk
subfamily_Ank-MTMR1_pd Subfamily Ank-MTMR1 1255-1411 3.5e-26 83.9 In-house 212-367 (405) alignment 
Range on Protein: 1255-1411
Range on HMM: 212-367/405.0
WPQCVSRMIELSNSIVALMnLYNSSVAICLEAGRSITTILSSLSQLLSDPYYRTCDGFQVLVEKEWLAFGHYFH-------KDTETSSPSFICFLDCVYQ
|   .  ..| .     |. |   |. .    |   |  ..||.|.| ||||||  |||||.|||||.||| |         . |  || |  ||||..|
wishiksileaatfsaeli.lkgnsilvhcsdgwdrtpqitsltqilldpyyrtivgfqvliekewlsfghkfslrlghlpgneeerspifqqfldccfq

ISQQYPTAFEFSYFYISFLAYHSTAGYFRTFIDDCEEKRLQSDANefylpdnLATINVWEFIKL
. .|.|  |||.   . |..    .  . ||...||  |.| . .       . || .|  ..|
llsqfpllfeftpslllfisdnihsckygtflnncekdrvqdqvk.......tktisiwsevnl
subfamily_pats1_pd Subfamily pats1 1334-1436 1.3e-08 25.7 In-house 552-644 (691) alignment 
Range on Protein: 1334-1436
Range on HMM: 552-644/691.0
SSPSFICFLDCVYQISQQYPTAFEFSYFYISFLAYHSTAGYFRTFIddCEEKRLQSDaNEFYLpdnlATINVWEFIKlRNRvsAAFYNELYEQIGDIVIP
 || |. ||| |.|. ...|. |||  ...  |  .| .. | .|.  ..| . .|. ....      .  .| ||. .|.  . | | || .  .    
fsPifvqfldlvwqlqkefPfhfefneslllllvkesfssrfGnfl..yseakrdse.rkvlk....rsksiwsfin.qnk..srfinllykhsasssss

SSS
|||
sss
C1_1 Phorbol esters/diacylglycerol binding domain (C1 domain) 1551-1585 1.4e-06 17.9 Pfam-A 10-45 (53) alignment 
Range on Protein: 1551-1585
Range on HMM: 10-45/53.0
RPVQCCYCTNIL-TRWSKAVHCKKCRIHVHEGCVNR
.|  |..| ..| . .. ...|. |   ||. |...
qptfCkhCgkflwgkgkqglkCswCqllvHkkCfek
PH PH domain 1647-1742 1.3e-09 28.5 Pfam-A 4-103 (104) alignment 
Range on Protein: 1647-1742
Range on HMM: 4-103/104.0
TGYLSKRGAKLKLWVPRFFVLYPdsPKVYYYEDFENwKTAEKPSGCIDLVDFKSFNLEQT------GRRGLIELHMKNK-THRLLSENINEAIRWKECIE
 |||.|.. .|| | .|.|||     ...|... .  |....| |.|.| | .    ..|       ..  .|...||. .. |  |.  |. || ....
eGyllkksellktwkkryfvLts..nyLlyfksskk.ksykapkgsiplndctvkkasstkfgaqkesnnyfeitfknvesyllsaeseeerkrWvqalk

QVI
...
nll
Tcp10_C T-complex protein 10 C-terminus 1669-1738 7.9e-06 11.9 Pfam-A 44-111 (179) alignment 
Range on Protein: 1669-1738
Range on HMM: 44-111/179.0
PDSPKVYYYEDFENWKTAeKPSGcIDLVDFKSFNLEQTGRRGLIELHMKNKTHRLLSENINEAIRWKECI
.|  ..||| . . ..|.  |.| .....| .  .|.. . |  |......| . |... .| |.. . .
adgrviYyyaeaqtthtt.ypdG.levlefpnkqtekrfkDGskeilfpdgtvkilnkdgeeeivypDGt