Synonym: CELE_C29E6.3, pph-2
Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
| Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
|---|---|---|---|---|---|---|---|---|---|
| 0050432 | (Phosphotyrosine protein) phosphatases II | 105-397 | 3e-49 | 163.4 | In-house | 14-303 (308) | alignment | ||
Range on Protein: 105-397
Range on HMM: 14-303/308.0
EKEKPKKKEKEKWSGEEASIKFVKSLGSINLKDEYDEIQKLPVQTE-RCKMWQSHSSRNRHNDSKCYDHNRIIVQmCKDDYINGSKINVP--HFTPSIYL
.... .....|.| .. .. | |.. .|. |. |...... | .. ... . ..||. | .|||.|.... ..|||| | .... ... . .
frdtsilvsslklsvldllkllekaldlglleeefeellsvkplleysvallpenkdkNrykdilpydhsRVkld.egsdYInAsyvdgyssklprkfIa
VQLPKmdsVDAVEEFWRVVFHEQCQTVHIIARPEELTNPAIDKLFCQESG-AWLYANGFFVNTRKVEKkeNAKADMFVVELLPEGCSNAVMCSVYLHTYW
| |. . || ||| |........ . ...| . .. . | | .|. ..|.|.....|. .. ....|| . |... .. .. .| |
tqgPl...pntvedFwrmvweqnvrvIvmLtklvengrekcaqYwplelgggsleygkftvtllseev..lddytvrtleltnlgdgesrtvthfhytnW
KPLFGPDRFGAQIRAAHQIAKNEnGNSPTVIASVNGSGRNAALLTLAVVEDQLTRGKEPKISEIVRTIREQRPQSVDSYIQYVSLYMATNWLIKTKL
. |. . . .. ... | ...|.|. . .| || .....| .. .|| ..... . |.|...|||||..| .. ||. ||.| ...|.||
pdhgvPpspeilldflelvrksl.pggpivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkklReqRpgmvqtpeqylflyralleylklkl
|
|||||||||
| 0039614 | (Phosphotyrosine protein) phosphatases II | 109-397 | 3.2e-47 | 156.8 | In-house | 8-293 (297) | alignment | ||
Range on Protein: 109-397
Range on HMM: 8-293/297.0
PKKKEKEKWSGEEASIKFVKSLGSINLKDEYDEIQKLPVQtERCKMWQSHSSRNRHNDSKCYDHNRIIVQMCKD-----DYINGSKINVPHF-TPSIYLV
.. . ...| ... ... | ... |. |. |...|.. .. ... . ..||. | .|||.|........ |||| | ...... |. ...
llesipiplsvldlllllekansktllllefeellslkpd.ysiallpenkdknrykdilpydhsrvklkpedgvdldsdYinAsyvdgydlltrkfIat
QLPKMDsvdAVEEFWRVVFHEQCQTVHIIARPEELTNpAIDKLFCQESGawlYANGFFVNTRKVEKKENAKADMFVVELlpEGCSnaVMCSVYLHTYWKP
| | . || ||| |........ . ...|| . .. . .|.| . ..|.|...|||.... . . |. .|.| .. ....| |
qgPlpe...tvedFwrmvweqgvtvivmLtklvelgr.kcaqywpeegg...tygdftvtllkvehldgytvrtlevtn..nges..rtvthfqytgwpd
LFGPDRFGAQIRAAHQIAKNEN---GNSPTVIASVNGSGRNAALLTLAVVEDQLTRGKEPKISEIVRTIREQRPQSVDSYIQYVSLYMATNWLIKTKL
|. . ... ... . . .. |... ...| || ...... . .|| ..... . |.|...|||||..| . ||. ||.| .|.|.||
hgvppslellleflelvrealaelpkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavqtpsqyrflydallellkrkl
|
|||||||||
| subfamily_Cele-PTP-4_pd | Subfamily Cele-PTP-4 | 110-401 | 9.1e-125 | 410.1 | In-house | 3-295 (302) | alignment | ||
Range on Protein: 110-401
Range on HMM: 3-295/302.0
KKKEKEKWSGEEASIKFVKSLGSINLKDEYDEIQKLPVQTERCKMWQSHSSRNRHNDSKCYDHNRIIVQMCKDDYINGSKINVPHFTPSIYLVQLPKMDS
...|||||..||...|.|||| ....|.|...|... |..|.||........|...| ...|.|........|.|.|.||..||..|.||.|.||||.||
veeekekWveeeeakklvksldtaevkkefkkidtmkvdlekCkafkknlkknqsedvpildsnlvkleaepdsyvnaskvevPeltrsiilaQlpkvds
VDAVEEFWRVVFHEQCQTVHIIARPEELTNpAIDKLFCQESGAWLYANGFFVNTRKVEKKENAKaDMFVVELLPEGCSNAVMCSVYLHTYWKPLFGPDRF
.|.||||||.||.|....|.|....|||.. ....||...||...... .|||.|||||.|..| ...|.|.|||||||.|...||..|.||. ..|...
edsveeFWrmvfqekivsvvilvgeeelkk.tlselfpkksgdykeygkmfvNnrkVekaeeek.tryviEvlPegcsnsvlanvyvltnWkqkkvpvky
GAQIRAAHQI-AKNENGNSPTVIASVNGSGRNAALLTLAVVEDQLTRGKEPKISEIVRTIREQRPQSVDSYIQYVSLYMATNWLIKTKL--PSGH
...|..|... ||.......|||.|.||.||..|.|||||. ..|..||||.|.|||..||.|||..|||..||||||.|....||.|. |...
aeliktaakvfakkikadentvivSknGaGRagafltlavaveklqkgkepnikeivksiRsqRpravdslkQyvslyialllyikkkvtkpeek
|
|||||||||
| 0043336 | (Phosphotyrosine protein) phosphatases II | 116-393 | 5.8e-46 | 152.6 | In-house | 3-277 (278) | alignment | ||
Range on Protein: 116-393
Range on HMM: 3-277/278.0
KWSGEEASIKFVKSLGSINLKDEYDEIQKLPVQTERCKMWQSHSSRNRHNDSKCYDHNRIIVQMCK----DDYINGSKINVPHFTPSIYLVQLPKMDsvd
.... . .. .. . |. |. |... .. | .. ... . ..||. | .|||.|....... .|||| | ........ ... | | .
svkdllkallelllnlktllllefeellsfkldtysiallpenkdknrykdilpydhsrvklsllggdldsdYinAsyvdgynvprkfiatqgPlpe...
AVEEFWRVVFHEQCQTVHIIARPEELTNPAIDKLFCqesGAWLYANGFFVNTRKVEKkeNAKADMFVVELLPEGCSNAVMCSVYLHTYWKPLFGPDRFGA
|| ||| |......|. . ...|| .. .. . | .|. ..|.|...|.|. .. ... |. . |... .. .| .. | |. .
tvedFwrmvwelgvttivmLtelvelgrvkcaqYwp...ggsltygdftvtllkeeh..lddytvrtlevtnlgdgesrtvthyhylgwpdhgvpeslsl
QIRAAHQIAKNE-NGNSPTVIASVNGSGRNAALLTLAVVEDQLTRGKEPKISEIVRTIREQRPQSVDSYIQYVSLYMATNWLI
.. ... . . |.|... ...| || .....| .. .|| ..... . |.|...|||||..| . ||. ||.| ...
lldflkavrealedsngpvlVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqRpgavqtpsqyrflyealleyl
|
|||||||||
| 0040438 | (Phosphotyrosine protein) phosphatases II | 117-399 | 2e-49 | 164.0 | In-house | 2-282 (317) | alignment | ||
Range on Protein: 117-399
Range on HMM: 2-282/317.0
WSGEEASIKFVKSLGSINLKDEYDEIQKLPVQTERCKMWQSHSSRNRHNDSKCYDHNRIIVQMCK----DDYINGSKINVPHFTPSIYLVQLPKmdsVDA
. ... ..... .. |..|. ....|.. | .. ... . ..||. | .|||.|.... .. .|||| | ...|.... . . | |. .
vldlllalldllksdftalleefedllslkldtysvaelpenkdknrypdilpydhsRVkLsplggdldsdYInAsyvdgpnlkrkfIatqgPl...pnt
VEEFWRVVFHEQCQTVHIIARPEELTNPAIDKLFCQesGAWLYANGFFVNTRKVEKkeNAKADMFVVELLPEGCSNAVMCSVYLHTYWKPLFGPDRFGAQ
|| ||| |........ . ..||| .. .. . . | .|. ..|.|.....|. .| ....|. . |.|. ... .. .| | |. .
vedFwrmvweqgvtvivmLteleelgrekcaqYwpl..getltygdftvtllseee..lagitlrtlevedlgdsesrtvthfhytgWpdhgvppspdll
IRAAHQIAKN-ENGNSPTVIASVNGSGRNAALLTLAVVEDQLTRGKEPKISEIVRTIREQRPQSVDSYIQYVSLYMATNWLIKTKLPS
.. ... .. |....|... ...| || ...... .. .|| ..... . |.|...|||||..| .. ||. ||.| ....|.||..
ldfleavrealedpggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrflydalleylkrkltl
|
|||||||||
| 0051299 | (Phosphotyrosine protein) phosphatases II | 122-393 | 3e-43 | 143.7 | In-house | 12-286 (288) | alignment | ||
Range on Protein: 122-393
Range on HMM: 12-286/288.0
ASIKFVKSLGSINLKDEYDEIQKLPVQTE-RCKMWQSHSSRNRHNDSKCYDHNRIIVQM----CKDDYINGSKINVPHFTPSIYLVQLPKMDsvdAVEEF
.. .. | .|..|..|...| .. . .. ... . ..||. | .|||.|..... .|||| | |...... . | |. . ||.|
klvlkllangltglleefeellsllpdltlsaallpenleknRysdilpydhsRVkLsvldgvegsdYinAsyidgynlkrkfIatqgPlpn...tvedF
WRVVFHEQCQTVHIIARPEELTNPAIDKLFCQesGAWLYANGFFVNTRKVEKKENAKADMFVVELL--PEGCSNAVMCSVYLHTYWKPLFGPDRFGAQIR
|| |........ .. ...|| . .. . . | .|. . ..|.....|.... . . |. | ..|... .. .. .| | || . . ..
WrmvweqnvrvIvmltklvelgrekcaqYwpl..ggsltygditvtllseevlddytvrtlevtnldlldgdgesrtvthfhytnwpdhgvpdspellld
AAHQIAKN-ENGNSPTVIASVNGSGRNAALLTLAVVEDQLTRGKEPKISEIVRTIREQRPQSVDSYIQYVSLYMATNWLI
... | ..|..|.|. . .| || .....| .. .|| ..... . |.|...|||||..| . ||. .|.| ...
flrlvrkalasgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlreqRpgmvqtpeqyrfvyealleyl
|
|||||||||
| subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 123-417 | 3.3e-20 | 67.4 | In-house | 10-306 (318) | alignment | ||
Range on Protein: 123-417
Range on HMM: 10-306/318.0
SIKFVKSLGSINLKDEYDEIQKLPVQTERC-KMWQSHSSRNRHNDSKCYDHNRIIVQMCKD----DYINGSKINVPHFTPSIYLVQLPKMdsvDAVEEFW
.. ... |...|. ||..... . .. . . . .||... ||| |. .|| .. |||| . |. . . . | | ...|.||
hvrrlresGelllseeyerlsrseetvtslkslepvnkaknryanilaydhtrvkLqmlegeegsDyinanyidGyrrkkayiaaqaPlp...etieDfW
RVVFHEQCQTVHIIARPEELTNPAIDKLFCQeSGAWLYANgFFVNTRKVEKKENAKADMFVVELlpEGCSNAVMCSVYLHTYWKPLFGPDRFGAQIRAAH
|.|. ..... .... || . ... . . .|. | . |. .. . .. | |. ..... . | .| | |. . .
rmvWeqnsavivmltqeeergkakvhryWPs.kgsrsygk.lvvelkeevelsdyvlrefkvtr..teeeesrqvrqyhytsWpdegvpesgaslldlvr
QIAKNE--NGNSPTVIASVNGSGRNAALLTLAVVEDQLTRGKEPKISEIVRTIREQRPQSVDSYIQYVSLYMATNWLIKTKLP--SGHEVVSKIKKFNEK
|. | . .|..|.|. | || ... .. ... . . ..|...||||. | ||. .| . ... . . ... |.|....|.
qvskaqqksgagpivvhCsaGvGrtGvfiavdillerikaealvDvfqtvkqlreqrnlmvqtedqyefiydvllealasgdtevdasdlrsrirelreq
ATRS
. |
dpes
|
|||||||||
| subfamily_PTPRK_pd | Subfamily PTPRK | 123-388 | 6.9e-20 | 66.1 | In-house | 12-272 (314) | alignment | ||
Range on Protein: 123-388
Range on HMM: 12-272/314.0
SIKFVKSLGSINLKDEYDEIQKLpvqTERCKMwQSHSSRNRHNDSKCYDHNRIIVQMCKDD----YINGSKINVpHFTPSIYLVQLPKMDsvDAVEEFWR
||. .| . .|.||. . . . .| . . ..|| .| ||. |.... ..| |||.. |. . |. ..| .. . |..|||
siallkraegygfkeeyeslfeg...wdaakk.denreknrsgdilaydrsrvflitidgdpssdyinaalids.ykrpaafivtqgPlq..etvkdfWr
VVFHEQCQTVHIIARPEELTNPAIDKLFCQESGAwlYANgFFVNTRKVEKKENAKADMFVVELLPEGCSNAVMCSVYLHTYWKPLFGPDRFGAQIRAAHQ
.|..|.| .. ... | .. | . ... | . . |. ..| ... . .| || | | .. . . .. | | . .. ..
lvydencasivmltelvevgrvkClkyWPedtev..ygd.ikvelvetellaelvvrifrveklargqeeirevrqfqflgWpdhdvPvsatgllklvrr
IAK-NENGNSPTVIASVNGSGRNAALLTLAVVEDQLTRGKEPKISEIVRTIREQRPQSVDSYIQYVSLYMA
. | .|... ..|. ..|.|| . .....| | . | . . ..|.|.|.... |. ||. .| .
vkksqeeeaGrivvhCsaGaGrtGtfiaidivldmieregvvdvfnavktlrsrkvnmveteeqykfiydv
|
|||||||||
| subfamily_Cele-PTP-8_pd | Subfamily Cele-PTP-8 | 123-394 | 5.2e-14 | 46.9 | In-house | 9-273 (288) | alignment | ||
Range on Protein: 123-394
Range on HMM: 9-273/288.0
SIKFVKSLGSINLKDEYDEIQKLpVQTERCKMWQSHSSRNRHNDSKCYDHNRIIVQMCKDDYINGSKINVPHFTPSIYLVQLPKmdsVDAVEEFWRVVFH
|..| . . || || . . . . . . . ..|.|... . | |. .. | ||. . .. . | | ..||.|.....
wirlvlqiaveglkkeyrdspne.asidiidsfianptrdryenlprcditrvklsddpdfyiaanvvssakykrrlicaqaPl...ngtieelWkmlle
EQCQTVHIIARPEELTNPAIDKLFCQESGAWLYANGFFVNTRKVEKKENAKADMFVVELLPEGCSNAVMCSVYLHTyWKPLFGPDRFGAQIRAAHQIakn
.. . . .... |. .. .. | . | . . ..| . . . .. || . .. ..|. |. |. . . .| . .
sdveyivmlcellekGkeksaeyfPsklGekarigrlctvvkkkradidklvkvsllriskegeekvivkilhlle.WdddgvPenylsplrllevl...
ENGNSPTVIASVNGSGRNAALLTLAVVEDQLTRGKEPKISEIVRTIREQRPQSVDSYIQYVSLY-MATNWLIK
.. . | |. | .|.|| ..| .. ..| | ... ||.| ... . ||. .. . . |.
kslqkPivvhssaGvGrtgtlililialeslrlddflgirsllaklreerfkaiqtemqylyvhrcvleelll
|
|||||||||
| subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 124-392 | 3.9e-20 | 67.1 | In-house | 14-282 (319) | alignment | ||
Range on Protein: 124-392
Range on HMM: 14-282/319.0
IKFVKSLGSINLKDEYDEIQKLP-VQTERCKMwQSHSSRNRHNDSKCYDHNRIIVQMCKD----DYINGSKINVPHFTPSIYLVQLPKMDsvdAVEEFWR
.| ..| |. |. |. .... .... ... . ...||... . ||. |.... .. |||| | |. . | |. . ..|.|||
lkalastgetllekefkllkeavndtfdsask.eenkkknryqnilaydrtrvvlseldgvegsdyinasfidgyqerekfiatqaPlen...tiedfWr
VVFHEQCQTVHIIARPEELTNPAIDKLFCQESgAWLYaNGFFVNTRKVEKKenakADMFVVELLPEGCSNAV---MCSVYLHTYWKPLFGPDRFGAQIRA
.|..|.. .| .... | . . |.. .| . | . |. . |.. .|. . .| . |. | . . . .| | |.. . .
mvWeeessivvmltklveklkvklkkywpeen.feey.Grlivtleeeeel....edyiirklklnkkssevetRevkhfqyteWpdhdvPekatslldl
AHQIAKNENG--NSPTVIASVNGSGRNAALLTLAVVEDQLTRGKEPKISEIVRTIREQRPQSVDSYIQYVSLYMATNWL
..|.| .. . | |. .|.|| . ..| .. ... . . ..|...| ||. |. || .| |
lkrirksrektqsgPivvhCsaGvGRtGtfivldamlervkeegvlDvfstvsrlRtqRnimvqrpeqYkfiyeallea
|
|||||||||
| subfamily_PTPN9_pd | Subfamily PTPN9 | 124-388 | 3.8e-16 | 54.0 | In-house | 7-285 (297) | alignment | ||
Range on Protein: 124-388
Range on HMM: 7-285/297.0
IKFVKSLGSINLKDEYDEIQKLPVQ-TERCKMWQSHSSRNRHNDSKCYDHNRIIVQMCKD----DYINGSKINVPHFTPSIYLVQLPKMDsvdAVEEFWR
...||. | |. || ||.. ||. | . . .. ...||..| |||. |. .. .. |||| . .. . .. | | .|..|||
vayvkekgkrGlskeyaeirnepveGtflasklranleknrytdvlcydetrvvlakvdedeasdyinanfvdGykqkkafiatqGplkk...tvsdfWr
VVFHEQCQTVHIIARPEELTNPAIDKLFCQESGAWLYANGFFVNTRKVEKKENAKADMFVVELLPEGCSNAVMCsvYLHTYWkPLFGPDRFG-------A
.|. ... .. ...| .| . . .|... . |.. .||..|. | ..... .. | |. . . | | .| . .
mvWeqevlvivmttrvvergrlkcgqyWpleeessaefgdlsvsnveveeeedykvrvleiknvkteesrkvth..fqflsW.PdyGvPssaaslldvle
QIRA-----AHQIAKNENG---NSPTVIASVNGSGRNAALLTLAVVEDQLTRGKEPKISEIVRTIREQRPQSVDSYIQYVSLYMA
..| .........| . | |. | || .. || . ..| . .. | |...|.|| |. ||. |.|
kvrekqalavkelgdewkghpsgPPivvhcsaGiGrtGtfitldiclsrleevgtvdvvetvkllrtqrafsiqtpeqyefcyla
|
|||||||||
| 0036941 | (Phosphotyrosine protein) phosphatases II | 125-398 | 6e-51 | 168.9 | In-house | 5-282 (297) | alignment | ||
Range on Protein: 125-398
Range on HMM: 5-282/297.0
KFVKSLGSINLKDEYDEIQKLPVQTE-RCKMWQSHSSRNRHNDSKCYDHNRIIVQMCKDDYINGSKINVPHFTPSIYLVQLPKMDsvdAVEEFWRVVFHE
.. |.|.. |. |..|...| .. . .. ... . ..||. | .|||.|.... ..||||.| ....... . . | |. . ||.||| |...
llekllflalllkefeellpllllgslsvallpenleknRykdilpydhtRVklddegsdYinAsyvdgydlkrkfIatqgPlpn...tvedFWrmvweq
QCQTVHIIARPEELTNPAIDKLFCQESGAWLYANGFFVNTRKVEKKENAKADMFVVELLPEGCSNAVMCSVYLHTYWKpLFG----PDRFGAQIRAAHQI
..... . ...|| . .. . | | .|. ..|.|....||..... ....|... |... .. .. .| | .| |. . . |......
nvtvIvmltelvelgrekcaqywpleegesltygdftvtllsvevvllddytlrtlevtdtgngesrtvthfhytgwp.dhgvpespaslldfielvrkv
AKNENGNSPTVIASVNGSGRNAALLTLAVVEDQLT---RGKEPKISEIVRTIREQRPQSVDSYIQYVSLYMATNWLIKTKLP
|. ....|... ...| || ...... .. .|| . ... | |.|...|||||..| .. ||. ||.| .|.|.||.
lkllpsggpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyeallellkkklt
|
|||||||||
| subfamily_PTPRD_pd | Subfamily PTPRD | 126-390 | 5.5e-19 | 63.2 | In-house | 16-278 (564) | alignment | ||
Range on Protein: 126-390
Range on HMM: 16-278/564.0
FVKSLGSINLKDEYDEIQKLPVQTERCKMWQSHSSRNRHNDSKCYDHNRIIVQMCKD----DYINGSKINVPHfTPSIYLV-QLPKMdsvDAVEEFWRVV
.|. ...... || .|.. . | . . ..|| .. |||.|.. .. . |||| | |. . .. |. | |. ...|.||| |
klkansdlkfeeeykkieegqqftweaankpaNkaKNRyanivaYdhsRVvLskvegdegsDYINAsfidgyr.krkayIAtqgPla...etiedFWRmv
FHEQCQTVHIIARPEELTNPAIDKLFCQEsGAWLYaNGFFVNTRKVEKKENAKADMFVVelLPEGCSNAVMCSVYLHTYWKPLFGPDRFGAQIRAAHQIA
. ....|. .. . || .. ..| . .. | | ... |. . |.... | . . |.. . . .| | |. . .. ...
weqnsstiVmltkleEkgkvkchkYWPek.gtety.geltVtleeeeeladyeirtfkl..kkkkssesreVrqFhFtsWPdhgvpesatslLdlirkvr
K-NENGNSPTVIASVNGSGRNAALLTLAVVEDQLTRGKEPKISEIVRTIREQRPQSVDSYIQYVSLYMATN
. ||... |.|. .| || . ... .. .... | | ..|...|.||. |.. ||. .. | .
alnepdagPivVhCSaGVGRTGtfividamlerikeektvDiyqyvkalrkqRnamVqteeQYiFiheail
|
|||||||||
| 0047943 | (Phosphotyrosine protein) phosphatases II | 127-393 | 2.9e-46 | 153.5 | In-house | 6-272 (273) | alignment | ||
Range on Protein: 127-393
Range on HMM: 6-272/273.0
VKSLGSINLKDEYDEIQKLPVQTE-RCKMWQSHSSRNRHNDSKCYDHNRIIVQMCKDDYINGSKINVPHFTPSIYLVQLPKMDsvdAVEEFWRVVFHEQC
|.||. |. |......|... . .. ... . ..||. | .|||.|..... ..|||| | ........ . . | |. . ||.||| |.....
ekllgltllleefelllslkplltysvallpenkdknrykdilpydhsrvklgdggsdyinAsyvdgynlkrkfiatqgPlpn...tvedfwrmvweqnv
QTVHIIARPEELTNPAIDKLFCQESGA-WLYANGFFVNTRKVEKkeNAKADMFVVELLPEGCSNAVMCSVYLHTYWKPLFGP---DRFGAQIRAAHQIAK
... . ...|| .. .. . .| | .|. . |.|.....|. .. ....|| . |... .. ....| | | . . |...... .
rviVmLtelvelgrekcaqYwpleggelsltygkftvtllseet..kddytvrtleltnlgtgesrtvthfhytgwpdhgvppslesllefielvrkale
NENGNSPTVIASVNGSGRNAALLTLAVVEDQLTRGKEPKISEIVRTIREQRPQSVDSYIQYVSLYMATNWLI
. ..|.|.|. ...| || .....| .. ||| ..... . |.|. .|.||| .| .. ||. ||.| ...
alpsngpvvVHCsaGvgRtgtfialdllldqlekeggvdvleavkllrsqRpgmvqtpeqyrflyealleyl
|
|||||||||
| subfamily_PTPN6_pd | Subfamily PTPN6 | 128-396 | 2.2e-14 | 48.2 | In-house | 21-300 (306) | alignment | ||
Range on Protein: 128-396
Range on HMM: 21-300/306.0
KSLGSINLKDEYDEIQKLPVQTERCKM---WQSHSSRNRHNDSKCYDHNRIIV---QMCKDDYINGSKINVPHFTP-SIYLVQLPKMdsVDAVEEFWRVV
.||. ....|..|.|. ... .. .. ..||.. . .||.|.|. .. .||||.. |. . |. . . |..|||.|
eslekagfeeefeelqqeeakkllsrkegakpenkeknryknilPfDhtrvilkepsvpgsdyinanyikkevkgsdksyiatqgcl..ettvsdFWrmv
FHEQCQTVHIIARPEELTNPAIDKLFCQESGAWLYANGFFVNTRKvEKKENAKADMFVVE-LLPEGCSNAVMcsVYLHTYWKPLFGPDRFGAQIRAAHQI
. |... . .. . | .. . . .|. | . |... ..... . ..|. .... |. | .. | | || . ...
wqensrvivmttkevErgkekCarYWPdeeekeeyGkisvtnvse.ksladYilRelsvskkkkkkeerevf..qyhfksWPdhgvpkdpgavLdfledv
AKNEN-----GNSPTVIASVNGSGRNAALLTLAVVEDQLTRG---KEPKISEIVRTIREQRPQSVDSYIQYVSLYMATNWLIKTK
.... . |.|. .| || ... . .. ..... . | ..|...|||| . | || .|.| . |.||
nrkqeeleeaeagpivvhCsaGiGRtGtfiviDillkliekkgldadidiqklvksvreqrsglvqteqqykfvykaikkyietk
|
|||||||||
| subfamily_PTPRG_pd | Subfamily PTPRG | 128-396 | 1.2e-12 | 41.9 | In-house | 14-290 (563) | alignment | ||
Range on Protein: 128-396
Range on HMM: 14-290/563.0
KSLGSINLKDEYDEIQKLPVQT-ERCKMWQSHS--SRNRHNDSKCYDHNRIIVQMCKD-----DYINGSKINVPHFTPSIYLVQLPKMdsvDAVEEFWRV
.. | | .. |....|. ... ... | .. .||. . ||. |. .. . |||| . |. . . | | | .. |||.
hadgdigfseefealqsetiskdldaehsqkpenkrKnRylnivaydrsRvklsplpgkkkklDYinAnyidGyqkskafiatqgplk...dtfddFWrm
VFHEQCQTVHIIARPEELTNPAIDKLFCQeSGAwLYANGFFVNTRKVEKKENAKADMFVVEL--L--PEGCSNAVMCSVYLHTYWKPLFGPDRFGAQIRA
.. .. ... .|. .| .. | . . .. . . . |. . |.. .|.. | . | . . | |.| |. ..
iWeqnvaiivmitnlvergrrkcdvYWPk.des.etygalqvtlieeevlalytvrtlviknlklkkkkqcdteklvrqyhytkWPdhgvPehslpvLif
AHQ-IAKNENGNSPTVIASVNGSGRNAALLTLAVVEDQLTRGKEPKISEIVRTIREQRPQSVDSYIQYVSLYMATNWLIKTK
... | |.. |.|. .| || .. | . |. . . . .....|| ||. | . ||. |. | .|..|
vkkssaankaeaGPivvHcsaGvgrtGtyivldtllkqiqqenavnvfgflkhiraqRnflvqteEqYiflhdalleaiask
|
|||||||||
| subfamily_PTPN3_pd | Subfamily PTPN3 | 129-383 | 4.1e-17 | 57.0 | In-house | 11-265 (280) | alignment | ||
Range on Protein: 129-383
Range on HMM: 11-265/280.0
SLGSINLKDEYDEIQ-KLP-VQTERCKMwQSHSSRNRHNDSKCYDHNRIIVQMCKDDYINGSKINVPHFTPS---IYLVQLPKMDsvDAVEEFWRVVFHE
.| | .. ..... | | .... ... |.||. | ||. |.... . |||| . .|. . . |.. .. .....||..|...
glesGavlaqfeqlyrkkpglaisaark.penlsknryrdilpydatrvklkesetdyinanyvnmeipstglvnryiatqGPla..ktatdfWqmvweq
QCQTVHIIARPEELTNPAIDKLFCQESGAWLYAnGFFVNTRKVEKKENAKADMFVVELLPEGCSNAVMCSVYLHtyWKPLFGPDRFGAQIRAAHQIAKNE
..... ... | . . ... . |. .| |. .| ..... .|.. . .. .. || | || .. ... |
ksslivmlttlverGrvkChqyWPetedeleyg.efsvkcekedetksyvlrelvlkdketkeerkilqlqyla..WpdhgvPddsadflefvervrklr
NG-NSPTVIASVNGSGRNAALLTLAVVEDQLTRGKEPKISEIVRTIREQRPQSVDSYIQYV
.| ..|.|. | || |..| . . . .. . .||||.|.|| |.. ||
sgkeePvvvhCsaGigrtGvlilletalalieaaepvypldivrtmrdqramlvqtasqyk
|
|||||||||
| subfamily_PTPN14_pd | Subfamily PTPN14 | 129-388 | 1e-14 | 49.3 | In-house | 19-291 (300) | alignment | ||
Range on Protein: 129-388
Range on HMM: 19-291/300.0
SLGSINLKDEYDEIQKLPVQTE-RCKMWQSHSSRNRHNDSKCYDHNRIIVQMCKD---DYINGSKINVPHFTPS-IYLVQLPKMdsVDAVEEFWRVVFHE
| . .. ||..|.| ... . . ..||..| |..||. .. .|. .||| |.|.|. . . |.| . .|..||..|. .
kleegkvfteyeripkkredallstaklpenaeknrfkdvlPyednrvelsptkenstgyinassikvsvggkersyivaqgPl..eltvqdfWqmvWeq
QCQTVHIIARPEELTNPAIDKLFCQE--SGAWLYANGFFVNTRKVEKKENAKADMFVVELLPEGCSNAVMCSVYlhTYWKPLFGPD------RFGAQIRA
. | . .... || . | | .. . . . | | |. .|. . . . .. || . |. | | | |. . ....
gvqlivmlteeeedgkeksfkyfPkleskkktvefgkfkvttkfsedsdsvittglklkhlpskeertvwhlqy..tDWpdhgvPeDvkgflsyLeevqs
----AHQIAKNENGNSPTVIASVNGSGRNAALLTLAVVEDQLTRGKEPKISEIVRTIREQRPQSVDSYIQYVSLYMA
... .... . | .. .| || |.. .. | ..| .| ......|||| |.. || .| .
vrrktnseveskeskPPvlvhCsaGvGrtGvlilsdlliatlehneeidikkvlarLreqrmllvqtlaqYkfvYkv
|
|||||||||
| subfamily_Cele-PTP-6_pd | Subfamily Cele-PTP-6 | 130-386 | 1.1e-15 | 52.4 | In-house | 13-270 (307) | alignment | ||
Range on Protein: 130-386
Range on HMM: 13-270/307.0
LGSINLKDEYDEIQKLPVQTERCKMWQSHSSRNRHNDSKCYDHNRIIVQM--CKDDYINGSKINVPHFTPSIYLVQLPKmDSvdAVEEFWRVVFHEQCQT
| .|.||. .. | .. . ... . .||..| || |..||.|.. ||| . . . | |. .. .. .|| .. |. ..
kgvqalvdefrvlakktpegvtveafsantdknryqdvkcqdkgrivvkfdglasdyihanylgiaikpkkficaqgpl.en..tqysfwamaiqekves
VHIIARPEELTNPAIDKLFCQESGAWL-YA-NGFFVNTRKVEKKENAKADMFVvELLPEGCSNAVMCSVYLHTYWKPLfgPDRFGAQI--RAAHQIAKNE
| .... ||.. .. . | | | .. .. .. .. |. | . .. .. | . | |. ||| || | . .
vimlckvielakikceqywpleegqklvfgeapntisvanlgakklapdedli.nvttlkvdwaqksrtiqhlqwenw..pdrgvpqinltainlleavr
NGNSPTVIASVNGSGRNAALLTLAVVEDQLTRGKEPK-ISEIVRTIREQRPQSVDSYIQYVSLY
. | |. | || .......| |.. .|.. | . ..|. .|.||. .. . .||. |.
ydtnpvvvhcsaGvGrsGtivaislvqdkmiaGinckdmkklveelrsqrhyaiqteaqylylh
|
|||||||||
| subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 130-395 | 4.9e-14 | 47.2 | In-house | 19-285 (305) | alignment | ||
Range on Protein: 130-395
Range on HMM: 19-285/305.0
LGSINLKDEYDEIQKLpVQTERCKMWQSHSSRNRHNDSKCYDHNRIIVQMCK--D--DYINGSKINVPHFTPSIYLVQLPkMDsvDAVEEFWRVVFHEQC
. .|. .|...... .. . . . ..||... .|..|||.. . | |||| | .. . . . | | .. . |..|||....|.
ysdkgleaqykslyee.eesidvgkkeankaknrlkeitlldddriiltekeslddsdyinasyvdgykrkkkyivaqgP.lk..ntvadfWrliveekv
QTVHIIARPEELTNPAIDKLFCQESGAWLYANGFFVNTRKVEKKENAKADMFVVELlPEGCSNAVMCSVYLHTYWKPLFGPDRFGAQIRAAHQIAKNENG
.|. .... | . . . .. . . | |. . .. .. . . .. .. . | | | |. .. .. ... |. .
stivmltklveggkdkCrqYWpesktekkefgefsvelksektasdyieRklkisi.ededkesrtvlqyqltdWPdhGvpqfatsllslikrvqkdqkk
N--SPTVIASVNGSGRNAALLTLAVVEDQLTRGKEPKISEIVRTIREQRPQSVDSYIQYVSLYMATNWLIKT
. | .. .| || . ... . ..| . .. . |.....|..|.. | . |||.|. | . ||..
dkgvpllVhCsagvgRtGvfiavdialerlkkEevvdvfevlkqlRskrmkmvqtldqYvflhdaldelitc
|
|||||||||
| subfamily_Sponge-PTP9_pd | Subfamily Sponge-PTP9 | 130-245 | 7.3e-08 | 26.5 | In-house | 12-130 (301) | alignment | ||
Range on Protein: 130-245
Range on HMM: 12-130/301.0
LGSINLKDEYDEIQKLPVQTERCKMWQSHSSRNRHNDSKCYDHNRIIV------QMCKDDYINGSKINVPHFTPSIYLVQLPkMDsvDAVEEFWRVVFHE
| .....|.|... .. .. .... ||... . ||.||||. ..|. .||| | |. . | | |. . .|||....|
khsnkfeeqykelkegedksctvglseenkalnrfknitvyddnriilkpkpnldlcqreyinasyidgysekkkfiaaqgp.mk..ktlvdfWrliwqe
QCQTVHIIARPEELTNPAIDKL
. ... ... .| |. .
kpvsivmvtnlkegtkskceqy
|
|||||||||
| subfamily_PTPN13_pd | Subfamily PTPN13 | 131-394 | 2e-19 | 64.9 | In-house | 9-270 (273) | alignment | ||
Range on Protein: 131-394
Range on HMM: 9-270/273.0
GSINLKDEYDEIQKLPVQtERCKMWQS--HSSRNRHNDSKCYDHNRIIVQMCKDdYINGSKINVPHfTPSIYLVQLPKMDSVDAVEEFWRVVFHEQCQTV
. . ..|..|...| . ..|.. .. . ..||. . ||. |.... ||| | |.|| | . . ..|..||..|. ... .
dqqqPaeefkelrelkpl.dtcevgkkkenkdknryrnvlPydetrvklgdegg.yinaslikvpv.gkdeyeyiacqGPlPetvkdfwqmvweqkaevi
HIIARPEELTNPAIDKLFCQESGAWLYANG-FFVNTRKVEKKENAKADMFVVELLPEGCSNAVMCSVYlhTYWKPLFGPDRFGAQIRAAHQIAKNENGNS
... | . .. . .. . | ... . |. ||.|... . . |. . | |. |. . . | | .. . .... .. ..
amvtlekekgkvkchrywPesknkklkvsnrlevellkvqkldgfvvralavkdsesgesrevahlnf..vkwPdhgvPssaaellqfvaevrrlqtdag
PTVIASVNGSGRNAALLTLAVVEDQLTRGKEPKISEIVRTIREQRPQSVDSYIQYVSLYMATNWLIK
| |. | || .|.|. || . . | || ...||||..|||| | . ||. | |. ..|
PivvhcsaGiGrsGtlitidvvlglierdkefdvkeivrklreqrqgvvqtkdqyifvykailevlk
|
|||||||||
| subfamily_PTPRB_pd | Subfamily PTPRB | 131-394 | 8.1e-17 | 56.2 | In-house | 23-286 (293) | alignment | ||
Range on Protein: 131-394
Range on HMM: 23-286/293.0
GSINLKDEYDEIQKLPV-QTERCKMWQSHSSRNRHNDSKCYDHNRIIVQMC----KDDYINGSKINVPHFTPSIYLVQLPKMDSvdaVEEFWRVVFHEQC
.....||.|.... |. . . ...||... |||.|. .. ..|||| . |. . . | | .. |..|||.|. ...
sdlrfseeyeelkavgkdqavkaaelavnraknrytnilpydhsrvkLaalkdesgsDYinanyipgynsprefiatqGPlpet...vddfWrmvwekks
QTVHIIARPEELTNPAIDKLFCQESGAWLYANgFFVNTRKVEKKENAKADMFVVELlpegCSNAVMCSVYLHTYWKPLFGPDRFGAQIRAAHQIA---KN
... .. . | .. . ... . || . |. . |..|. . .| .. | .| | |.. . .. ... ..
siivmltqlvekgkvkCeeYWPadeepvlyGd.ikvtlvaeeeledwvirelkiek....ekeerkvrqyhftsWpdhgvPektktlldfvrtvreaiek
ENGNSPTVIASVNGSGRNAALLTLAVVEDQLTRGKEPKISEIVRTIREQRPQSVDSYIQYVSLYMATNWLIK
.. ..|.|. | || ....| . ..... | || .||.| . | . ||. .. . |..
taskrPivvhCsaGvGRtGtfialdrllqaieeedyvdifgivaelReeRnllvqtekqYifihqcvldllr
|
|||||||||
| subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 132-390 | 6.7e-21 | 69.8 | In-house | 26-287 (298) | alignment | ||
Range on Protein: 132-390
Range on HMM: 26-287/298.0
SINLKDEYDEIQK----LPVQTERCKMWQSHSSRNRHNDSKCYDHNRIIVQM----CKDDYINGSKINVPHFTPSIYLVQLPKMdsvDAVEEFWRVVFHE
.....|. .... .. .. . .. ..||. | .|. |.... . |||| | .. . ... . | | . .||.|||.| .|
ltgyalefqrlnsvsseieeeekevarkpenkkkNRyadiialdssRvvLekedadeesdYiNAsflhaykgrnafiatqaPlt...etvedFWrmvtee
QCQTVHIIARPEELTNPAIDKLFCQEsGAWLYaNGFFVNTRKVEKKENAKADMFVVELLPEGcsNAVMCSVYLHTYWKPLFGPDRFGAQIR--AAHQIAK
. .|. .. ||| . . | . .| |. | . . |. .. |.. . . |. | . . .| | | . . . . .
digtiVmltnleeldktkyhkywPde.gkety.geitvsllskeefadlivrklkvskkkee..kerevrqlhftsWpdkgvpenatsvldllrkvrasq
NENGNSPTVIASVNGSGRNAALLTLAVVEDQLTRGKEPKISEIVRTIREQRPQSVDSYIQYVSLYMATN
...||.| .. .| || . . | ... . . . ..|...|..||..|.. ||| .|.|.
qqagnkpvivqCsaGvgRsGtfiaidsvlervkkeqvvDvfqvvkvlRkkrpgavqteeqYvfiyeavl
|
|||||||||
| subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 132-389 | 1.3e-17 | 58.8 | In-house | 20-275 (288) | alignment | ||
Range on Protein: 132-389
Range on HMM: 20-275/288.0
SINLKDEYDEIQKLPVQTERCKMWQSH-SSRNRHNDSKCYDHNRIIVQM----CKDDYINGSKINVPHFTPSIYLVQLPKMDSVdavEEFWRVVFHEQCQ
....||. . .| . . .. ... ..||... ||..|. .. . |||| | |.. . . | | .|.| ..||..|. .. .
rtgfseeynsLaalektksvtagrlavnakknRyrnilpyDekrvklkkleeeagaDYinasyidgekkkkkyiatqgPladtv...ndfWelvyenkts
TVHIIARPEELTNPAIDKLFCQESGAWLYANgFFVNTRKVEKKENAKADMFVVEllpeGCSNAVMCSVYLHTYWKPLFGPDRFGAQIRAAHQIAKNENGN
|. .. | . .. . .. .| . . | ......|. . .| . . | .. | |. . .|. ... .
tivmltelveggktkCeeYWPdadkpknyGs.vtvtlveskeledfvlrkllle....kkkteleitqyqylaWpdhgvPeskapllellrqvkvanqad
-SPTVIASVNGSGRNAALLTLAVVEDQLTRGKEPKISEIVRTIREQRPQSVDSYIQYVSLYMAT
| .. .| || ..| . |.. . . . ..| .|.||.. |. ||. .| .
tgpiivhCsaGvGrtgtFialdalidaveeedyiDvagtvaklRkqRallvqtlkqYefiyevl
|
|||||||||
| subfamily_CG7180_pd | Subfamily CG7180 | 133-387 | 2.8e-18 | 60.6 | In-house | 17-284 (296) | alignment | ||
Range on Protein: 133-387
Range on HMM: 17-284/296.0
INLKDEYDEIQKLPVQTERCKMWQSHSSRNRHNDSKCYDHNRIIVQMC----KDDYINGSKINVpHFTPSIYLV-QLPKMDsvdAVEEFWRVVFHEQCQT
. | |. ...| . .. . . .||. . ||.||.... |.|||| . .. . . |.| . || . .|.||||.|. |....
veyklelkltprleigdCagglrkenreknrdvkvvPyDynRvvLekldGeeksdYinavyvds.flkkkeyivteapkke...tvdefWrlvydeeisa
VHIIARPEELTNpAIDKLFCQESgAWLYANgFFVNTRKVEKKENAKADMFVVELL--------PEGCSNAVMCSVYLHTYWKP-LFGPD---RFGAQIRA
| ..... . .. . . ..| | . .||.. .... | | .| . . . .. .. | |. | . .|
vvvLtktfdfak.mypsywpnks.keqyge.ifveiveekqyanlkirtfkltkkivalteqekqvkaetRivklfqlteWeledkvPlstnalielrrr
AHQIAKNE---NGNSPTVIASVNGSGRNAALLTLAVVEDQLTRGKEPKISEIVRTIREQRPQSVDSYIQYVSLYM
.... .. . ..|.|. | .|..| . |.. . ... . .| . | |.|.|..||| |.. .| .|
vrlwrekvdedpeegPvvvvssdGasRsGvylaidanlelvekeeevdvFeavktlrrsRpqLvenveeYkyiYd
|
|||||||||
| 0046845 | (Phosphotyrosine protein) phosphatases II | 134-397 | 1.1e-43 | 145.1 | In-house | 1-278 (284) | alignment | ||
Range on Protein: 134-397
Range on HMM: 1-278/284.0
NLKDEYDEIQKLPVQ---TERCKMWQSHSSRNRHNDSKCYDHNRIIVQM-----CKDDYINGSKINVP-----HFTPSIYLVQLPKMDsvdAVEEFWRVV
.|..|. |...| | . .. ... . |.||. | .|||.|..... .|||| | .... .... . . | |. . ||.|||.|
gleeefeellsltvklllslsvallpenlsknRykdilpydhsRVklksldgdledsdYinAsyvdgydldltyikkkfIatqgPlpn...tvedFwrmv
FHEQCQTVHIIARPEELTNPAIDKLFCQEsGAWLYANGFFVNTRKVEKKENAKADMFVVELLpeG-CSNAVMCSVYLHTYWKPLFGP---DRFGAQIRAA
........ . ...| . .. . .| | .|. ..|.|.....|.|.. . .. .. | | ... ... .. .| | | . . . .|..
weqnvrvIVmltelvengrekcaqYwple.gevltygdftvtllseevkddytvrtleltnl..gytgesrtvthfhytswpdhgvppspedlleflrlv
HQIAKNENGNSPTVIASVNGSGRNAALLTLAVVEDQLTRGK---EPKISEIVRTIREQRPQSVDSYIQYVSLYMATNWLIKTKL
... .| .|..|.|. . .| || .....| .. .|| ... .. . |.|. .|||||..| .. ||. .|.| ...|.||
rellenlpgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvqtleqyrfvyealleylklkl
|
|||||||||
| subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 134-385 | 1.6e-19 | 65.0 | In-house | 7-251 (267) | alignment | ||
Range on Protein: 134-385
Range on HMM: 7-251/267.0
NLKDEYDEIQKLPVQTER--CKMWQSHSSRNRHNDSKCYDHNRIIVQMCKDDYINGSKINVpHFTPSIYLVQLPKMDsvDAVEEFWRVVFHEQCQTVHII
... |...|.|. .. . . . . ||| .|. ||..|.|.. ...||| | .. . | ..| .. .. .|. |. .... .. ..
eiekefelikkisdtsstisqsiaeknqernrlddnlpyddtrvilrtkeeeyinasyveg.yktknafivtqdplk..ntitdfltvihdqkvpvivll
ARpeeLTNPAIDKLFCQESGAWLYANGFFVNtRKVEKKENAkADMFVVELLPEGCSnAVMCSVYLHTYWKPLFGPDRFGAQIRAAHQIAKNENGNSPTVI
. | ... . | . . |. . .||.|| .. ..|| . | | ..| . |. . . . . |||| | |.
tk...vftdnirlfwPPkmgqakkyqdltve.hslekeend.yqiitlelkfknes.ahnvtlyyykkwnintnnkpylkplfgilaknqlengnrPlvv
ASVNGSGRNAALLTlavVEDQLTRGKEPKISEI---VRTIREQRPQSVDSYIQYVSL
| .| || ..|. .. || | |. .|.| .| ||.||. ||. .|. .
acsdGvGrsGtflv...idsqleraktegvsdifdflrkirsqriglvdtkeryiyi
|
|||||||||
| DSPc_SM00195 | 135-391 | 2.8e-43 | 143.5 | In-house | 2-260 (263) | alignment | |||
Range on Protein: 135-391
Range on HMM: 2-260/263.0
LKDEYDEIQKLPV-QTERCKMWQSHSSRNRHNDSKCYDHNRIIVQMCK----DDYINGSKINVPHFTPSIYLVQLPKmdsVDAVEEFWRVVFHEQCQTVH
|| |...... .. ... ... .|.||... ..|||.|.... . .|||| . |.... . .. . | |. . ||.|||.|..|.....
lkeefekleestspketteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPl...pstvedFWrmvweekvkiiv
IIARPEELTNPAIDKLFCQESGAWLYANGFFVNTRKVEKKEnAKADMFVVELLPEGCSNAVMCSVYLHTYWKPLFGPDRFGAQIRAAHQIAKNENG-NSP
.. ..|| . .|. . .||| . . |....||||. .. . ..|| ||.... . .| .. |. || .. ... | .. ..|
mlteeeengkekcdrywpeesggketfgkisvklvevekkk.deiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkkskstssgp
TVIASVNGSGRNAALLTLAVVEDQLTRGKEPKISEIVRTIREQRPQSVDSYIQYVSLYMATNW
.|. . .| || ....|. .. ..|...|...|.|||. .|.|||..|.. || .|.|
ivVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaile
|
|||||||||
| PTPc_SM00194 | 135-391 | 2.8e-43 | 143.5 | In-house | 2-260 (263) | alignment | |||
Range on Protein: 135-391
Range on HMM: 2-260/263.0
LKDEYDEIQKLPV-QTERCKMWQSHSSRNRHNDSKCYDHNRIIVQMCK----DDYINGSKINVPHFTPSIYLVQLPKmdsVDAVEEFWRVVFHEQCQTVH
|| |...... .. ... ... .|.||... ..|||.|.... . .|||| . |.... . .. . | |. . ||.|||.|..|.....
lkeefekleestspketteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPl...pstvedFWrmvweekvkiiv
IIARPEELTNPAIDKLFCQESGAWLYANGFFVNTRKVEKKEnAKADMFVVELLPEGCSNAVMCSVYLHTYWKPLFGPDRFGAQIRAAHQIAKNENG-NSP
.. ..|| . .|. . .||| . . |....||||. .. . ..|| ||.... . .| .. |. || .. ... | .. ..|
mlteeeengkekcdrywpeesggketfgkisvklvevekkk.deiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkkskstssgp
TVIASVNGSGRNAALLTLAVVEDQLTRGKEPKISEIVRTIREQRPQSVDSYIQYVSLYMATNW
.|. . .| || ....|. .. ..|...|...|.|||. .|.|||..|.. || .|.|
ivVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaile
|
|||||||||
| 0045450 | (Phosphotyrosine protein) phosphatases II | 135-395 | 3e-42 | 140.8 | In-house | 29-306 (307) | alignment | ||
Range on Protein: 135-395
Range on HMM: 29-306/307.0
LKDEYDEIQKLPV---QTERCKMWQSHSSRNRHNDSKCYDHNRIIVQMCK-----DDYINGSKI--------NVPHFTPSIYLVQLPKMDsvdAVEEFWR
|. |. ..... | . .. ... . ..||. | .|||.|.... .. .||||.| . ...... . . | |. . ||.|||
llkefekllsvtvfllgeysiallpenkdknrykdilpydhtRVklssldgsledsdYiNAsyvrvpllllldgydlkrkfIatqgPlpe...tvedFwr
VVFHEQCQTVHIIARPEELTNPAIDKLFCQEsGAWLYANGFFVNTRKVEKKENAKADMFVVELLpEGCSNAVMCSVYLHTYWKPLFGPDRFGAQIRAAHQ
......... . ...||... ... . .| | .|. . |.|.....|.... . . |. | .|... .. .. .| | |. | .. ..
mlweqgvtvivmltelvelgrekcaqywPde.geeltygnftvtllseehldgytvrtlevtdl.dgtgesrtvthfhytgwpdhgvppsfeelldfiee
IAK--NEN-GNSPTVIASVNGSGRNAALLTLAVVEDQLTRGKE---PKISEIVRTIREQRPQSVDSYIQYVSLYMATNWLIKT
. | .|. ...|... . | || ...... .. .|| .... . . |.|...|||||..| .. ||. ||.| .|...
vrkaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrflyeallelllk
|
|||||||||
| subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 135-389 | 1.1e-14 | 49.5 | In-house | 36-287 (319) | alignment | ||
Range on Protein: 135-389
Range on HMM: 36-287/319.0
LKDEYDEIQKLPVQTERC--KMWQSHSSRNRHNDSKCYDHNRIIVQMC----KDDYINGSKINVpHFTPSIYL-VQLPKMdsvDAVEEFWRVVFHEQCQT
|. |. . ||.|. . .|| . .|.|.. .. |||| | .. . . |. | |. .....|||... .| |
levefrracklgvnladqtfanldqnkdknriinilafdknvvklerliGeefsdyinasfvtG.yqrkdkyiaaqGPld...ntladfWrmiweyncst
VHIIArpeeltnpaidKLFCqeSGAWLYAN-----GFFVNTRKVEKKENakadmFVV---ELLPEGCSNAVMCSVYLHTYWKPLFG-PDRFGAQ---IRA
. ... | | | | | |. ||. .. .|| || .| . . | | | || ..
ivllt...........kdkc..sqywplkivikeerfkvkvdsveetae.....yvvrdielsedgkekdirkitqfhflGwpdvGvpdypsdlmrlvkk
AHQIAKNENGNSPTVIASVNGSGRNAALLTLAVVEDQLTRGKEPKISEIVRTIREQRPQSVDSYIQYVSLYMAT
. . . ||.. . |. |.|| . ..| |. |.. . | . ..|| .|.||.. |....|| .|.|
vrhltskenhranivvhcsaGvGrtGvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysal
|
|||||||||
| subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 135-393 | 1.5e-13 | 45.5 | In-house | 17-276 (281) | alignment | ||
Range on Protein: 135-393
Range on HMM: 17-276/281.0
LKDEYDEIQKLPVQ-TERCKMWQSHSSRNRHNDSKCYDHNRIIV----QMCKDDYINGSKINVPHfTPSIYLV-QLPKMdsvDAVEEFWRVVFHEQCQTV
.. ||...... |. | . . .||... ||. |. | . . |||| . .. . . |.. | | .....||..|. .. ...
fieeyeklaaigvdntataskadenvlknrYsnivaYDatrvkvtpneenkntDYinanfvpgyk.gekeyiatqgPvP...aslvafWqmvweqkvsai
HIIARPEELTNPAIDKLFCQESGAWLYANGFFVNTRKVEKKENAkADMFVVeLLPEGCSnaVMCSVYLHTYWKPLFGPDRFGAQIRAAHQI--AKNENGN
...| | . . . ... . |.. .|.. ||.. . | . .| . . . .| | |. . . ... ..... .
vmvtreieagklkChrYWPddnselkygdvtvkstaeeekatyi.erkfkl.eresget..reveqlaytaWPdhGvPattkellefrkevlkltekktk
SPTVIASVNGSGRNAALLTLAVVEDQLTRG-KEPKISEIVRTIREQRPQSVDSYIQYVSLYMATNWLI
| || | || . ..| . ..... .| .....|. .|..| | . .|| .| | .
aplvihCsaGvGrtGtyialDrlvkaveaeleeldvkavvaelrkernlmvqtvvqyefvykavldal
|
|||||||||
| subfamily_Urchin-PTP-4_pd | Subfamily Urchin-PTP-4 | 135-388 | 1.7e-13 | 44.8 | In-house | 22-231 (392) | alignment | ||
Range on Protein: 135-388
Range on HMM: 22-231/392.0
LKDEYDEIQKLPVQTERCKMWQSHSSRNRHNDSKCYDHNRIIV----QMCKDDYINGSKINVPHFTPSIYLVQLPKMDSVDaveEFWRVVFHEQCQTVHI
. .|. .. .. ... . .||... || .|... .. ..||.| | |. . . | |.. |.| .|||.||.|. |. .
ffeefhdlpgpdiypqtvaqkeinlkknryknilpydsarvkleviddipdsdylnasyipsfdnekayiasqgpnaasld...dfwrmvfqenvttiam
IARPEELTnpaidklfcqesgawlyangffvntrkvekkenakadmfvvellpeGCSNAVMCSVYLHTYWKPLFGPDRFGAQIRAAHQIAKNENGNS-PT
... .| .| .. . | | | . . .. ... . . |
vtklkegd..............................................kgddartvaqfhftewPdkdvpkhtssllkfikevkadfGqythpl
VIASVNGSGRNAALLTLAVVEDQLTRGKEPKISEIVRTIREQRPQSVDSYIQYVSLYMA
.| | || . .... | . . . . ..| ||..|| |.. || .| |
iihcsagvgrtgvvisidsvvahakktrmvdvfnfvtnirrkrpymvqtkeqyafiyga
|
|||||||||
| subfamily_Ptp69D_pd | Subfamily Ptp69D | 136-389 | 4.1e-20 | 67.1 | In-house | 25-282 (307) | alignment | ||
Range on Protein: 136-389
Range on HMM: 25-282/307.0
KDEYDEIQKLpVQTERCKM--WQSHSSRNRHNDSKCYDHNRIIVQMC----KDDYINGSKINVPHFTPSIYLVQLPkMDSvdAVEEFWRVVFHEQCQTVH
. ||..... .|. . .||..| | .|..|.... . |||| | |. . . . | | ... ...|||.. . ...
akeyekLear.eidkstkvsekkenalknRyedikafDktRvkLkkingkedsdYinasfikgykekkkfiaaqdP.vea..tigDfWRmiaeqevtliv
IIARPEELTNPAIDKLFCQEsGAWLYAnGFFVNTRKVEKKENAKADMFVVELLP-EG--CSNAVMCSVYLHTYWKPLFGPDRFGAQIRAAHQI-AKNENG
... .| .. ..| . .| | |.. . ||... . | |. . | .| || |. . .. .|. ...
mlsnlteknrkkcakYWpie.devqyg.dilvklvseekhsdyiiReldvskkkeesgevedsrkvvqyhytgWkDskvPevargllklieqvrelykln
NSPTVIASVNGSGRNAALLTLAVVEDQLTRGKEPKISEIVRTIREQRPQSVDSYIQYVSLYMAT
.|| |. .|.|| . ...|... .|| .. .| |.|. .|.||. |.|. ||| || |
rsPivvhCsaGvgrsgifvaldsllqqlkaedkvdifetvkdLrsqRnllvqsleqYvflyral
|
|||||||||
| subfamily_PTPRA_pd | Subfamily PTPRA | 136-388 | 5.9e-18 | 59.8 | In-house | 35-290 (330) | alignment | ||
Range on Protein: 136-388
Range on HMM: 35-290/330.0
KDEYDEIQKLPVQTE-RCKMWQSHSSRNRHNDSKCYDHNRIIVQMCK----DDYINGSKINVPHFTPSIYLVQLPKMDsvdAVEEFWRVVFHEQCQTVHI
..|.. . |.|. . .|| . ||..|.|... . |||| | |. . . | || . .||.|||... . .|. .
reefnalPagpiqatlelaskeenkeknrvvnilPydfsrvilsvkeGveesdyinasfidGykekdkfiaaqGPkee...tvedfwrmiweqksativm
IARPEELTNPAIDKLFCqESGAWLYANgFFVNTRKVEKKENAKADMFVVELLPEGC-SNAVMCSVYLHTYWKPLFG-PDRFGA--QIRAAHQIAKNENGN
.. .| . . . . |.. | | |. .... .. |.|. ||... ... .| | .| | .. .. . .. ...
ltelkerkeekcaqywP.deGlvtyGn.irvevedetvlvdytvrkflvqqlpdatrekksrlvrqfhftswPdvGvPfepiGmlkllkkvkklnqqsag
sPTVIASVNGSGRNAALLTLAVVEDQLTRGKEPKISEIVRTIREQRPQSVDSYIQYVSLYMA
| |. | || ....| | ... . . |.|. .| |||| | . ||. .| .
.pivvhcsaGvGrtGtfivldavlervkaerkvdvfefvkrlrlqrpqmvqtdeqyefiykv
|
|||||||||
| subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 136-388 | 2.7e-16 | 54.3 | In-house | 22-272 (315) | alignment | ||
Range on Protein: 136-388
Range on HMM: 22-272/315.0
KDEYDEIQKLPVQTERCKMWQSHSSRNRHNDSKCYDHNRIIV----QMCKDDYINGSKINVPHFTPSIYLVQLPKMDSVDaveEFWRVVFHEQCQTVHII
.|. .. .. .| . ..||... .|..|... . ..|||| |.|. . . | |. ||| .|||.|..|. |. ..
seefhdlpdPdiyrqrvaretinfkknryknilPldsarvkleviddsPdsdyinasyiksvdddkayiasqgPlkasvd...dfwrmvlqekvttivmv
ARPEEltNpaiDKLFCQESGAWLYANGFFVNTRKVEKKE-NAKADMFVVELLPEGCSNAVMCSVYLHTYWKPLFGPDRFGAQIRAAHQIAK-NENGNSPT
. .| . ||. |. |. . ||| . .| .|. . .| . . . | | . . .. .. ... |.. . .
tkkqe..g...dkikcrqywPdrkadsvefGsikvellsleadtdgvarklvtrkseesrtvtqfqftewPdkGvdkqtssllklikevkadngkkefsl
VIASVNGSGRNAALLTLAVVEDQLTRGKEPKISEIVRTIREQRPQSVDSYIQYVSLYMA
.. . | || .... | .|. |.. . ..|...|..||. | . .| .| |
lvhcsaGvGrtGvvisidevvaqikrtrsvdvfnfvknlrakrpylvqteeeyafiyda
|
|||||||||
| subfamily_PTPN5_RR_pd | Subfamily PTPN5_RR | 136-389 | 8.7e-13 | 43.0 | In-house | 5-264 (274) | alignment | ||
Range on Protein: 136-389
Range on HMM: 5-264/274.0
KDEYDEIQKLPVQT-ERCKMWQSHSSRNRHNDSKCYDHNRIIV--QMCKDD---YINGSKINVPHFTPSIYLVQLPKMdsVDAVEEFWRVVFHEQCQTVH
|| ..| .||. .. .. ....||... .. |... . .|. ||| | .. . .|. . . .|..|||....|..| .
kdlekeflelPlnfdqeeldvfgsqtknryktilPnensrvllesessededssyinanyikGydeeskayvatqGPl..pntvadfWrmiyqeevqviv
IIARPEELTNPAIDKLFCQESGAWLYA--NGFFVNTRKVEKKENAKADMFVVEllpeGCSNAVMCSVYLHTYWKPLFGPDRFGAQIRAAHQIA---KNEN
.... .| . . | .. .. . ... ....|. .... . .|.. ... . |..| | ||. . .. ... ..||
mltklkeaneqkCavyfPdaedyeiserygdveikvekiverndysvrklvlk....ylerersvkhywytdWPdhksPddantlldlvleveesreeen
GN-SPTVIASVNGSGRNAALLTLAVVEDQLTRGKEPKISEIVRTIREQRPQSVDSYIQYVSLYMAT
. .|.|. | || . .. . || . . . .|| .| .| |.. || .. |
aklapvvvhCsaGiGrtGcfiaisiavrqlreeivvdvlkivcnlrldrGGmvqtseqyelihral
|
|||||||||
| subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 136-388 | 9.8e-13 | 42.7 | In-house | 27-274 (315) | alignment | ||
Range on Protein: 136-388
Range on HMM: 27-274/315.0
KDEYDEIQKLPVQTERCKMWQSHSSRNRHNDSKCYDHNRIIVQM----CKDDYINGSKINVPHfTPSIYL-VQLPKmdsVDAVEEFWRVVFHEQCQTVHI
|..|. | .. . .||. . ||. |. . . . ||.| . |. . |. | |. | .|..|||.||.|.. .. .
kqdyesipggqlhpldvakkienkqknryiniiaydksrvqlpllendphsdyvnanfidGyn.kkrryiaaqgpn...vasvkdfwrlvfeedigkivm
IARPEELTNPAIDKLFCQEsgAWLYanGFFVNTRKVEKKEnakaDMFVVELLPEGCSNAVMCSVYLHTYWKPLFGPDRFGAQIRAAHQIAKN--ENGNSP
.. | . .| . . .| | . ||| |... . . | | . . | || | | .. . .. .| .| ..
ltnlvegekrkaekywpdk..kviy..Gkitvtrkseevn....teytvrtlsvvfgdnirevvqlhytswpdmgvpkytiplmnlirtvkqhhtnsvga
TVIASVNGSGRNAALLTLAVVEDQLTRGKEPKISEIVRTIREQRPQSVDSYIQYVSLYMA
|. .| || ...|| | ||. . . .... .|..| . |.. || .| |
ivvhcsaGvGrtGtfitldavldqaeaenaidvynfitgvrqnrikmvqvaeqyqfiyda
|
|||||||||
| subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 137-236 | 3.7e-06 | 21.0 | In-house | 11-112 (297) | alignment | ||
Range on Protein: 137-236
Range on HMM: 11-112/297.0
DEYDEIQKlPVQTERCKMWQSHSS--RNRHNDSKCYDHNRIIVQ--MCKDDYINGSKINVPHFTPSIYLVQlPKMDSVDAVEEFWRVVFHEQCQTVHIIA
.|.| . . ..| . . || .||..| .| .|. .. . . |||| . |. .. . . ..|..||..|.... ... ..|
aekdllld.eargesfssakrnsslrknryrdilatddtrvkllrviterdyinadyvvfpdeeadlkyil.aqGplsatvddfwtlvaeqdvrvivmva
RPEE
. .|
klqe
|
|||||||||
| subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 141-393 | 1.4e-09 | 32.4 | In-house | 3-264 (270) | alignment | ||
Range on Protein: 141-393
Range on HMM: 3-264/270.0
EIQKLPVQTERCKMWQSHSSRNRHNDSKCYDHNRIIVQMCKDD----YINGSKINVPHFTPSIYLVQLPKMDSvdAVEEFWRVVFHEQCQTVHIIARPEE
|..| .... . .. ||..| . |.... ..| ||| .. . . |. ... ....|||....|. ... ... ||
eldkeetsesdlpeaargkklnRyadiLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpt..tlksfwrmiweekvtaivmttgleE
LTNPAIDKLFCQESGAWLYANGFFVNTRKVEKKENAKADMFVVELLPEGCSNAVMcsVYLHTYWKPLFGPDRFG---------AQIRAAHQIAKNENGNS
. .. . .|.. . . .......... . . ..| .| .. .. . .. | | . . . .|| .. |. . ..
kgrkkCerYWpaepkekvkledgkikvlalseekeegyiltrlrleekgeerrlv..HfwyntWpdhgvpreedsslstdqllkmlravrrsekeldkae
PTVIASVNGSGRNAALLTLAVVEDQLTRGKEPKISEIVRTIREQRPQSVDSYIQYVSLYMATNWLI
|... .| || |..| . | . |. . .|.. .|..|.. |. || || | .
PllvHcsaGvgRtGtlialDiavrlLeetkkvdvlaiieelRkdRmalvqhpeqyeflykavveya
|
|||||||||
| subfamily_Sponge-PTP5_pd | Subfamily Sponge-PTP5 | 142-386 | 6.9e-11 | 36.6 | In-house | 15-259 (283) | alignment | ||
Range on Protein: 142-386
Range on HMM: 15-259/283.0
IQK--LPVQTERCKMWQSHSSRNRHNDSKCYDHNRIIVQMCKDDYINGSKINVPHF--TPSIYLVQLPKMDsvDAVEEFWRVVFHEQCQTVHIIARPEEL
... .| . ... . . ||... .| .|. .. |||| . | | . |.. .| ..| .||..||.|. .. .... |
lkrlsvpdldadiasadenkrknrnqeivpadqwrvelksesrdyinavfipvsksykqdkkyiiaqsPld..rtvvdfWkmvfdekitaivmltklqed
TNPAIDKLFCQEsGAWLYANgFFVNTRKVEKKENAKADMFVVELlPEGCSNAVMCSVYLHTYWkPLFGPDRFGAQIRAAHQIA--KNENGNSPTVIASVN
. . . . .. |. | . | | || .. ... . .... . | | .|.. . .. ..|. ..| |. .
lrikCsqyWPkr.GsedyGe.ftvtlrkettsnsfiikelllrv.nssakstlllahyqvidW.leygeqaiinslvkfnkvislqteskkgPivvhCst
GSGRNAALLTLAVVEDQLTRGKEPKISEIVRTIREQRPQSVDSYIQYVSLY
| || |....... ... . ..|. .||||. | . || ..
giGrtavfiaasasvkdaltesvvdvfavvkimreqrmmavqtldqyklvh
|
|||||||||
| subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 145-386 | 6.3e-15 | 49.6 | In-house | 41-276 (290) | alignment | ||
Range on Protein: 145-386
Range on HMM: 41-276/290.0
LPVQTERCKMWQSHS--SRNRHNDSKCYDHNRIIVQMCK-DDYINGSKINvpHFTPSIYLVQLPKMDsvdAVEEFWRVVFHEQCQTVHIIARPEELTNPA
|||| |... . .||. | | | |.|.. ||. .. . . | | . | .| ..||.| .|. .. .. | ..
lpvqylerkifdkntefkknrykdvvcndktrvilkdGydGdyvhanyvk..GlkamfiltqGalkd...tvidiwrmvlqekvaaivmlceliedGkak
IDKLFCQESGAWLYANGFFV-NTRKVEKKENAKADMFVVELLPEGCSNAVMcsVYLHTYWKPLFGPDRFGAQIRAAHQIAKNengNSPTVIASVNGSGRN
.. . ...| | . | . . .| .| . .. | .| . . . | . | .| . . | . | |. | ||
ceqyypekeGevltfGeitvlcseeddkdaniikktlsvrdkdsGkehklk..hlkikswpdksvalstlallrtlrilrka...sGpvvvhcsaGiGrt
AALLTLAVVEDQLTRGKEPKISEIVRTIREQRPQSVDSYIQYVSLY
.. .. | . |. ||| .. ..||..|. | .||. |||. |
GtfvaievglqilldGkeldlldlvralrnsrlnsvqvdiqylalv
|
|||||||||
| subfamily_PTPN12_pd | Subfamily PTPN12 | 146-399 | 5.3e-20 | 66.5 | In-house | 28-283 (290) | alignment | ||
Range on Protein: 146-399
Range on HMM: 28-283/290.0
PVQTERCKMWQSHSSRNRHNDSKCYDHNRIIVQMCK----DDYINGSKINVPHFTPSIYLVQLPKMdsvDAVEEFWRVVFHEQCQTVHIIARPEELTNPA
| . . ... .||. | ||..|. .. . .||||.. |. .. . . | | .....|||.... . . | .. | ||
kvysteagekeenvkknrykDilPydksrvelskieeeegsdYinanfikgvegkleyiaaqgPLp...ktlddfWrmiweknveivvmaCrevelgkkk
IDKLFCQESGAWLYANGFFVNTrkvEKKENAKADMFVVELLPEGCSNAVMCSVYLHTYWKPLFGPDRFGAQIRAAHQIAK-NENGNSPTVIASVNGSGRN
.. . .| . | . | |.. |.... . |... | | .. . . .| | | .. .. ... . .|. ..| |. | ||
CerYWpeegeeelefgefevtl...eeekavdddflirtLkveaqkesrkvyqfhYtaWPDhgvPssaksllelielvrelqesedaPlvvhCsaGvGrt
AALLTLAVVEDQLTRGKEP---KISEIVRTIREQRPQSVDSYIQYVSLYMATNWLIKTKLPS
..... | ..| ..| | .. ..|...|.||. | . ||. .|.| |....| .
Gtiiaidyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavaelvqkelei
|
|||||||||
| subfamily_PTPN23_pd | Subfamily PTPN23 | 148-388 | 4.4e-24 | 79.8 | In-house | 33-275 (288) | alignment | ||
Range on Protein: 148-388
Range on HMM: 33-275/288.0
QTERCKMWQSHSSRNRHNDSKCYDHNRIIVQMCKDDYINGSKI-NVPHFTPSIYLVQLPKMDSvdaVEEFWRVVFHEQCQTVHIIARPEELTNPAIDKLF
. . . . .|..||..| |||||. .. |||||| | . .. .|.. | |. . . .||..|.... ... .. .||| .| .|. .
rkrsiaiaklyseknrsrdilPyDhnRvklrgskDDYinAsfvkdlspgcPdfiatqaPlqst...lnDFWlmvyeqkssviVmllskeelgkpkvdrYw
CQESGAWLYANGFFVNTRKVEKKENAKADMFVVELLPEGCSNAVmCSVyLHTYWKPLFGPD---RFGAQIRAAHQ--IAKNENGNSPTVIASVNGSGRNA
.. |. . . | ..|.. |. .. .| |.. . | . . | | | |. . . . .... |.... . | |. |.||
Pedkgetvkfgdlsvtlksvretethvervlkletldadavksv.shl.qltsWpelGvPasPetllqfldevesayeavqrksktPlvvhCsaGvgRtg
ALL-TLAVVEDQLTRGKEPKISEIVRTIREQRPQSVDSYIQYVSLYMA
.. |.|.. .. . | ..|...|||| .| |. .| |
vfalvyaavrelekgnglldiiqvvsrlreqRrfmvqekeqlkfsyea
|
|||||||||
| 0045098 | (Phosphotyrosine protein) phosphatases II | 149-395 | 1.8e-25 | 85.4 | In-house | 24-274 (278) | alignment | ||
Range on Protein: 149-395
Range on HMM: 24-274/278.0
TERCKMWQSHSSRNRHNDSKCYDHNRIIvqmckdDYINGSKINVPhfTPSIYLVQLPKMdsvDAVEEFWRVVFHEQCQTVHIIARPEELTNPAIDKLFCq
. . .. .. ..|| | .|||.|.. |||| | |... .. . | |. . |. ||| ......... ... .||.. .. .
eitpalylgnldknRykdilpydhsrVk......dYINAsyidgy..pkkfIatqgPlp...stvadfwrmlwelgitvivmltelvelgrekcaqywp.
EsGAWLYANGFFVNTRKVEKKENAKADMFVVELLPEGCSNAVMCSVYLHTY-WKPLFGPDRFG---AQIRAAHQIAKNEN--------------GNSPTV
| | .|. ..|.|.. ..| .. .. |. | .. |. . | . | .|. . ... .| . . .. |..
e.ggsltygdftvtllseevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllsslllldsggpvl
IASVNGSGRNAALLTLAVVEDQLtrGKEPKISEIVRTIREQRPQ-SVDSYIQYVSLYMATNWLIKT
. | || ..| . . ..| .. . |.|...|.|||. .| . ||. ||.. .|..
VHCsaGvgRtGtlvaaylmlell..eggvdlleavkelrsqRpglavqnleqyrflyefllelllr
|
|||||||||
| subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 150-386 | 4.9e-10 | 33.7 | In-house | 38-276 (290) | alignment | ||
Range on Protein: 150-386
Range on HMM: 38-276/290.0
ERCKMWQSHSSRNRHNDSKCYDHNRIIVQ------MCKDDYINGSKINVPHFTPSIYLVQLPKMDsvdAVEEFWRVVFHEQCQTVHIIARPEELTNPAID
.. .| . .|| .. || |||... |...||| . |. . . ...| | .. . .||... .|.. . .. | .
vtvgltssnkllnRfanivvyddnritLrpisghkDCtneyinAcyikgykekkqyiatqgpvsn...tlvdFWkliwqekvtiivmltniieegkvkCq
KLFCQESGAWlyANGFFVNTRKVEKKENAKADMFVVELLPEGcSNAVMCSVYLHTYWKPLFGPDRFGAQIRAAHQIAK--NENGNSPTVIASVNGSGRNA
. . ... . . | .. . |. .. . |. .. .. . | | |.. . . . ... | .|| . |. .. || |
qYWpdsdtka..ygefsikllneetlneyierklevknknsa.gakqsvtqyqitnwdstgkvtnpqtillvieemyktqrkrgntsivvHCSdtvgrsa
ALLTLAVVEDQLTRGKEPKISEIVRTIREQRPQSVDSYIQYVSLY
....|. .. . ..... | |.|.|| . || ..
vfcaaattinkcktegvidvfqvlksqRiqkpgsvqtvqqyqgif
|
|||||||||
| 0040439 | (Phosphotyrosine protein) phosphatases II | 151-394 | 4.6e-38 | 126.6 | In-house | 4-247 (249) | alignment | ||
Range on Protein: 151-394
Range on HMM: 4-247/249.0
RCKMWQSHSSRNRHNDSKCYDHNRIIVQMCKD----DYINGSKINVPHFTPSIYLVQLPKMDsvdAVEEFWRVVFHEQCQTVHIIARPEELTNPAIDKLF
.. ... . ..||. | .|||.|.... ... |||| | |....... . . | | . .|| ||| ......... . ...|| . .. .
svallpenkdknrypdilpydhsrvklsilpglflsdyinAsyidgyyikrrfiatqgPlpe...tvedfwrmlwelgitvivmLtslvelgrekcaqyw
CQesGAWLYANGFFVNTRKVEKKENakADMFVVELLPEGCSNAVMCSVYLHTYWKPLFGPDRFGAQIRAAHQIAKNEN---GNSPTVIASVNGSGRNAAL
. | .|. ..|.|....||.|.. ....|| . .... ... .. .| | |. | .. ... | . ..|... . .| || ...
pl..ggsleygdftvtllsvevkdd..ytvrtleltnlydgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtf
LTLAVVEDQLTRGKEPKISEIVRTIREQRPQSVDSYIQYVSLYMATNWLIK
... . .|| . .. . |.|...|.|||..| .. ||. ||.| .|..
iaaylmleqlekelgvdleeavkllrsqRpgavqnpeqyrflyeallelll
|
|||||||||
| 0042113 | (Phosphotyrosine protein) phosphatases II | 151-393 | 1.6e-36 | 121.4 | In-house | 2-243 (245) | alignment | ||
Range on Protein: 151-393
Range on HMM: 2-243/245.0
RCKMWQSHSSRNRHNDSKCYDHNRIIVQMCK----DDYINGSKINVPHFTPSIYLVQLPKMDsvdAVEEFWRVVFHEQCQTVHIIARPEELTNPAIDKLF
.. ... . ..|| | .|||.|.... . .|||| | ......|| ... | | . || ||| .......|. . ..||| . .. .
svallpenkdknrysdilpydhtrvklspdggdldsdyinasyvdgyritpkfiatqgPlpe...tvedfwrmlwelgittivmLteeeelgrvkcaqyw
CQesGAWLYANGFFVNTRKVEKkeNAKADMFVVELLPEGCSNAVMCSVYLHTYWKPLFGPDRFGAQIRAAHQIAKNEN--GNSPTVIASVNGSGRNAALL
. | |. ..|.|.....|. ... ....|. ..|.. .. .|... | || ... . . | . .| |... . | || ....
pl..gesltygdftvtllseeh..lddytvrtlevtnlgddesrevihyhylpwpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfi
TLAVVEDQLTRGKEPKISEIVRTIREQRPQSVDSYIQYVSLYMATNWLI
.. . .|| . .. . |.|. .|.|||..| . ||. ||.| .|.
aaylmleqlekelgvsleeavkelrsqRpgavqtpsqyrflyeallell
|
|||||||||
| subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 151-389 | 1.8e-11 | 38.8 | In-house | 41-284 (325) | alignment | ||
Range on Protein: 151-389
Range on HMM: 41-284/325.0
RCKMWQSHSSRNRHNDSKCYDHNRIIVQMCKD----DYINGSKINVPHFTPSIYLVQLPKMDSvdaVEEFWRVVFHEQCQTVHIIARPeELTNPAIDKLF
. | ..|| .. .|..|.... || |||| | .. | |. .. ....||.|. .| | .. .| . . .
kvamkpenkaknrfknvvaldksrvvletkkddpssdyinasylrddkkkdvflaaqaPltat...indlWrlvldWrcsvvvvlnel.dlgkdrcavyw
CQESGAWLYANGFFVNTRKVEKKENAKADMFVVELLPEGCSNAVMCsvYLHTYWKPLFGPDRFGAQIRAA------H-QIAKNENGNSPTVIASVNGSGR
.| | |. |. | .|. . .. | .| . .| . . |. . . | . | . .. | .. .| .. ..| ||
pkemgksktfGglevklrtieeisdyvhrvldvkqvkkGetrsvkq..fqlqswddmGvqkrpatlisilqlvkavservtantkastpilvhcsaGvGr
NAALLTLAVVEDQLTRGKEPKISEIVRTIREQRPQSVDSYIQYVSLYMAT
....| . ... . | . |. .|..||. |.. ||. .| |
tGvfislysalakvieesrvdifgfvkklrkdrpsmvetvdqyiliyeal
|
|||||||||
| 0037934 | (Phosphotyrosine protein) phosphatases II | 152-393 | 1.7e-33 | 111.6 | In-house | 4-242 (243) | alignment | ||
Range on Protein: 152-393
Range on HMM: 4-242/243.0
CKMWQSHSSRNRHNDSKCYDHNRIIVQMckDDYINGSKINVPhftPSIYLVQLPKMDSVDA-VEEFWRVVFHEQCQTVHIIARPEELTNPAIDKLFCqes
. ... . |.||. | .|||.|.... .||||.. |.|. | ... |.| ..|. ...||| ......... . ...||. ....
iallpenlsknrysdilpydhsrvkleg..sdyinanliyvt...prliatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqywp...
GAWlYANGFFVNTRKVEKKENAKADMFVVELLP-EGCSNAVMcsVYLHTYWKPLFGPDRFGAQIRAAHQIAK---------NENGNSPTVIASVNGSGRN
| . . ..|.|.. ..| ... . ....| |. .... |. |... | || . .. ... . ......|... . | ||
gev.tygdftvtllseehlddytvrtlllenldlddltrlvi..hyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgRt
AALLTLAVVEDQLtrgkEPKISEIVRTIREQRPQ-SVDSYIQYVSLYMATNWLI
..|... .. ..| . . |.|...|||||. .| .. ||. ||.| .|.
Gtliaaylmllll....gvdleeavkllreqRpgkavqtpsqyrflyeallell
|
|||||||||
| subfamily_Sponge-PTP6_pd | Subfamily Sponge-PTP6 | 152-389 | 2.1e-13 | 44.6 | In-house | 41-275 (439) | alignment | ||
Range on Protein: 152-389
Range on HMM: 41-275/439.0
CKMWQSHSS-RNRHNDSKCYDHNRIIVQ----MCKDDYINGSKINVpHFTPSIYLV-QLPKMdsvDAVEEFWRVVFHEQCqtVHIIArpeeLTNPAIDKL
. . |... .||..| .|| |...| . . ||| |. .... .|. | || .....|||.|..... |.|. |||
slaaqeydqtknrykdvgafdhtrvtlqeipgvphshyinanyikG.yyddklyiatqgpkk...ettddfwrlviekkt..vtivm....ltnlvesyk
FCQESGAWLYANGFFVNTRKVEKKENAKADMFVVELLPEGCSNAVMCSvYLHTYWKPLFGPDR--FGAQIRAAHQIAKNENGNSPTVIASVNGSGRNAAL
. .. | . |..| . . . |.. . . . . .. | | . . . | . |.... | |. | || ..
ywpsdaevcygdiavrvdrnielpnyvirgfkvfnerdttekertvlq.fhyiawpdknvpaqashvldflrainsandkeeygpvvvhcsagvGrtGti
LTLAVVEDQLTRGKEPKISEIVRTIREQRPQSVDSYIQYVSLYMAT
..| . .|| .. | ||. .|.|| | |.. ||| .| |
ialdialeqlklenkvdikgivkvlrkqrkqmvqalcqyvfiynav
|
|||||||||
| subfamily_Cele-PTP-15_pd | Subfamily Cele-PTP-15 | 155-388 | 2.2e-12 | 41.6 | In-house | 32-265 (285) | alignment | ||
Range on Protein: 155-388
Range on HMM: 32-265/285.0
WQSHSSRNRHNDSKCYDHNRIIVQMCKDDYINGSKINVPHFTPSIYLVQLPKMdsVDAVEEFWRVVFHEQCQTVHIIARPEELTNPAIDKLFCQESGAwL
... ||. | .| . |.... ||| | . .| | |. . ... .||.....|. | ... | . .. | .
yeanpdlnryadvrcieetrvvlknhdrdyihaswmrmpgkdqstyittqgpl..petlsdfwhmiyqekiayvlmlctlfeggvekcalyypeklge.v
YANGFFVNTrKVEKKENAKADMFVVELLPEGCSNAVMCSVYLH----TYWKPLFGPDRFGAQIRAAHQIAKNENGNSPTVIASVNGSGRNAALLTLAVVE
| . | | ||.| | . | .| .|. .| . |. | . . | . . | .. | || |... .
vkfgkyeit.lteckeeaiagtilnaltvintedasseplymnhvqvpwwpdqlapedarpmielykwvkkvnpkekpicvhcsagvgrtatfvgidyat
DQLTRGKEPKISEIVRTIREQRPQSVDSYIQYVSLYMA
.. . .. .||| .| | |.|.|..|.. ||.
irimenpniemldivremramrfqavqshmqflflyvv
|
|||||||||
| subfamily_PTPRN_pd | Subfamily PTPRN | 155-388 | 4.5e-12 | 40.3 | In-house | 53-287 (297) | alignment | ||
Range on Protein: 155-388
Range on HMM: 53-287/297.0
WQSHSSRNRHNDSKCYDHNRIIVQM----CKDDYINGSKINVPHFTPSIYLV-QLPKmdsVDAVEEFWRVVFHEQCQTVHIIARPEELTNPAIDKLFCqE
. ..||... |||.|. .. |.|||| | | ..|. | | . | .||..|... . . ..| || . .. . .
aeknvkknrskavlpydhsrvklkeeasaeksdyinasaildhdprapayiatqgpl...astvadfwqmvweqGvvvivnltrleeegvkqckrywp.d
SGAWLYANgFFVN--TRKVEKkENAKADMFVVELLPEGCSNAVmcSVYLHTYWKPLFGPDRFGAQIRAAHQIAKNENGNS-PTVIASVNGSGRNAALLTL
|. .| . |. . .. .. | . | . .| . . . |. | . . .. | | | | |. . .|.|| . . .
eGsevyhi.yevhlvsehiwc.ddylvrsfylknlqtsetrtv..tqfhflswpeegvPasaksllefrrkvnksyrGrscpivvhcsdGaGrtGvyili
AVVEDQLTRG-KEPKISEIVRTIREQRPQSVDSYIQYVSLYMA
.| ..|..| || |. . .|.|||. | . |. ..|
dlvlnrllkGvkeidiaatlehlrdqrpglvktkdqfefalta
|
|||||||||
| subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 156-387 | 6.9e-14 | 46.5 | In-house | 45-272 (287) | alignment | ||
Range on Protein: 156-387
Range on HMM: 45-272/287.0
QSHSSRNRHNDSKCYDHNRIIVQMCKDDYINGSKINVPHFTPSIYLVQLPKmdsVDAVEEFWRVVFHEQCQTVHIIARPEELTNPAIDKLFCQESGawLY
.. .|| .. .| .|.... ...|||| . |. . . . | .... .||... ... ... .... .| .. . . . .|. ..
sqnkdknRltqilvpdnyrvllkgehpdyinavfidgykekkafiiaesPm...fntarnfWkliddrnvtaivmlcqekendeevcyqyWpeeks..vv
ANGFFVNTRKVEKKENAKADMFVVELLPEgCSNAVMCSVYLHTYWKPLFGPDRFGAQIRAAHQIAKNE--NGNSPTVIASVNGSGRNAALLTLAVVEDQL
. .. . |.... . |. . .. . | | |. .. . . .. |.. .||.. |. .. || | .. |. ..
lGeyniellneevnagyierklevknknk.agdkqqvkqyqitnWdstgkvtepqtillvieemyktqrkrgntsivvhCsdtvGrsamfcaaattinkc
TRGKEPKISEIVRTIREQRPQSVDSYIQYVSLYM
. . .... | |.|.|| || ..
kteGviDvfqvlksqriqkpgsvqtveqykfind
|
|||||||||
| subfamily_PTPN1_pd | Subfamily PTPN1 | 156-366 | 3.5e-13 | 43.9 | In-house | 30-244 (290) | alignment | ||
Range on Protein: 156-366
Range on HMM: 30-244/290.0
QSHSSRNRHNDSKCYDHNRIIVQMCKDDYINGSKINVPHFTPSIYLVQLPKMDsvdAVEEFWRVVFHEQCQTVHIIARPEELTNPAIDKLFCQESG-AWL
.. ..||. | . ||| ||... . |||| | ..... | | | | . .|. ||..|.......| .. . | . . . |. |
penrnlnryrdvspydhsrikleradndyinaslveleeakrsyiltqGPlpn...tvdhfWqmvWeqkskavvmlnkvvekeqikcaqywPqgeeekel
YA--NGFFVNTRKVEKKENAKADMFVVELLPEGCSNAVMcsVYLHTYWKPLFGPDRFGAQIRAAHQIAK---NENGNSPTVIASVNGSGRNAALLTLAVV
. |. . |.|.. . .. .| | . .. . .| | . |. .| .. ... . . |.|| | || .. . .
lledtklkvkliseerksyytvrllelenlktqetreil..hfhyttwpdfgvpespaaflkflfkvresGslssdvGpavihcsaGiGrsGtfclvdtc
EDQLTRGKEPKI---SEIVR
.. . .. . .. .
lvliekkddlssvdikkvll
|
|||||||||
| subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 158-390 | 8.5e-15 | 49.6 | In-house | 51-281 (297) | alignment | ||
Range on Protein: 158-390
Range on HMM: 51-281/297.0
HSSRNRHNDSKCYDHNRIIVQMCKDD----YINGSKINVPHFtpSIYLVQLPKMDSvdaVEEFWRVVFHEQCQTVHIIARPEELTNpAIDKLFCqESGAW
...|.... || .|..... || |.| | ... . . | |. .. |..||..|..|| .|. ... .| .. . . ..|
nfeksRYkniLPydssRvkLaivnddpdsDyvnasfvkgnkh..rlittqmPmkat...vadfWamvldeqvstivmlnddnerdk.kcaryWs.dkgvt
LYANgFFVNTRKVEKKENAKADMFVVEllPEGCSNAVMCSVYLHTYWKPLFGPD--RFGAQIRAAHQIAKN--ENGNSPTVIASVNGSGRNAALLTLAVV
. . | . |...| ..|. . . . | ...| . . . . ... |. .| ..| .. ..| || . |||. |
tfGd.vsvvllsvsereGfikrelevt..kgkakarrvvkqyqfveWPdkaverkdsassllklisevrkdfsqnaegPllvhclaGvGrtgvlltidsv
EDQLTRGKEPKISEIVRTIREQRPQSVDSYIQYVSLYMATN
. | || | ..|. .|..||. | || .| | .
vaeakrekevdifglvkklrqerpylvqtkeqykfvyvavl
|
|||||||||
| subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 158-389 | 1.9e-14 | 48.9 | In-house | 25-251 (284) | alignment | ||
Range on Protein: 158-389
Range on HMM: 25-251/284.0
HSSRNRHNDSKCYDHNRIIVQMC----KDDYINGSKINVPHfTPSIYL-VQLPKMdsvDAVEEFWRVVFHEQCQTVHIIArpeeltnpaidKLFCqeSGA
.|| . .|.|.. .. |||| | |. . |. | |. .....|||... .| |. ... | | |
nkdknrighilafdknvvklerliGeefsdyinasfitGyq.rkdkyiatqGPld...ntladfWrmiweyncstivllt...........kdkc..sqy
WLYA-----NGFFVNTRKVEKKENakadmFVV---ELLPEGCSNAVMCSVYLHTYWKPLFG-PDRFGAQ---IRAAHQIAKNENGNSPTVIASVNGSGRN
| . | |. ||. |. .|| || .| . . | | | || .. . . . ||.... |. |.||
wplkivikeerfkvkvdsveesee.....yvvrdielsedgkekdirkirqfhflgwpdvgvpdypsdlmrlvkkvrhltskenhranivvhcsagvgrt
AALLTLAVVEDQLTRGKEPKISEIVRTIREQRPQSVDSYIQYVSLYMAT
. ..| |. |.. . | . ..|| .|.||.. |....|| .|.|
gvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysal
|
|||||||||
| Y_phosphatase | Protein-tyrosine phosphatase | 159-388 | 2.7e-41 | 136.9 | Pfam-A | 2-232 (235) | alignment | ||
Range on Protein: 159-388
Range on HMM: 2-232/235.0
SSRNRHNDSKCYDHNRIIV-QMCK-DDYINGSKINVPHFTPSIYLVQLPKMDSVdavEEFWRVVFHEQCQTVHIIARPEELTNPAIDKLFCQESGAWLYA
...||..| .||..|. . . .. |||| . .. . . .. . | | ... |.|||.|..|..... .... || . .... . .|.. |.
kkknRykdilpydktrvklkgsegpsdYInAnyvkgykekkkfIatQgPlksti...edFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeeslty
NGFFVNTRkVEKKENAKADMFVVELLPEGCSNA---VMcSVYLHTYWKPLFGPDRFGAQIRAAHQIAKNE-NGNSPTVIASVNGSGRNAALLTLAVVEDQ
. ..|... ...||. |. .. . | . ... . ... .| |. |. . .. ... |.. . ..|.|. . .|.|| . ...| .. .|
gdikvelk.ekekedekeytlrklelkkkkeesekrev.kqlhytnWpdhgvpespkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldilleq
LTRGKEPKISEIVRTIREQRPQSVDSYIQYVSLYMA
|....|... .||...|.|||..|.|. ||. ||.|
leaeeevdvlqivkelRkqRpgmvqsleqYiflyka
|
|||||||||
| Y_phosphatase | Protein-tyrosine phosphatase | 159-388 | 2.7e-41 | 136.9 | In-house | 2-232 (235) | alignment | ||
Range on Protein: 159-388
Range on HMM: 2-232/235.0
SSRNRHNDSKCYDHNRIIV-QMCK-DDYINGSKINVPHFTPSIYLVQLPKMDSVdavEEFWRVVFHEQCQTVHIIARPEELTNPAIDKLFCQESGAWLYA
...||..| .||..|. . . .. |||| . .. . . .. . | | ... |.|||.|..|..... .... || . .... . .|.. |.
kkknRykdilpydktrvklkgsegpsdYInAnyvkgykekkkfIatQgPlksti...edFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeeslty
NGFFVNTRkVEKKENAKADMFVVELLPEGCSNA---VMcSVYLHTYWKPLFGPDRFGAQIRAAHQIAKNE-NGNSPTVIASVNGSGRNAALLTLAVVEDQ
. ..|... ...||. |. .. . | . ... . ... .| |. |. . .. ... |.. . ..|.|. . .|.|| . ...| .. .|
gdikvelk.ekekedekeytlrklelkkkkeesekrev.kqlhytnWpdhgvpespkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldilleq
LTRGKEPKISEIVRTIREQRPQSVDSYIQYVSLYMA
|....|... .||...|.|||..|.|. ||. ||.|
leaeeevdvlqivkelRkqRpgmvqsleqYiflyka
|
|||||||||
| subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 159-389 | 7.2e-21 | 69.5 | In-house | 10-238 (250) | alignment | ||
Range on Protein: 159-389
Range on HMM: 10-238/250.0
SSRNRHNDSKCYDHNRIIVQMCK----DDYINGSKINVPHFTPSIYLVQLPKmdsVDAVEEFWRVVFHEQCQTVHIIARPEELTNPaIDKLFCQESgAWL
.||. | .|. |.... | |||| | ... . . . | | ....|.|||.|..|. .|. ... .| . . . . | |
keknryadiialdssrvvLekekgdkesdyinasflhgyderkafiatqgPl...qatiedfWrmvleeksgtivmLtnLkesekt.yhqywPvek.aek
YANgFFVNTRKVEKKENAKADMFVveLLPEGCSNAVMCSVYLHTYWKPLFGPDRFGAQIRAAHQIAKNEN--GNSPTVIASVNGSGRNAALLTLAVVEDQ
| . |. . |.. . . .. | . .. .. . .. | |. | . ... .... ||.| .. .| || | ... | ..
yGd.vtvsllskeefadytkrklk..lskakkaderivrqlhfvvWPdkgvPevatavLellkkvqasqqqagnaPvivqCsaGvgrsGafiaidavler
LTRGKEPKISEIVRTIREQRPQSVDSYIQYVSLYMAT
| . | . ......|..||..|.| |||..|..
lkkekvvdvfkvikvlrkdrphavesleqyvfvyeii
|
|||||||||
| subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 159-388 | 7.8e-14 | 46.4 | In-house | 8-235 (239) | alignment | ||
Range on Protein: 159-388
Range on HMM: 8-235/239.0
SSRNRHNDSKCYDHNRIIVQMC----KDDYINGSKINVPHFTPSIYLVQLPKMDSvdAVEEFWRVVFHEQCQTVHIIARpeeLTNPaiDKLFCQEsgAWL
..||. . |||.|.... . |||| | . .| |. . . .|||....|. . ... | . | |.. |
kaknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcvei..ssgdfwrmmwqerrcvivmltg...lieg..hkkkchq..ywp
YANGFFVNTRKVEKKENAKADMFVVELLPE--GCSNAVMCSVYLHTYWKPLFGPDRFGAQIRAAHQIAKNE-NGNSPTVIASVNGSGRNAALLTLAVVED
. ..| | .| . || . .. | .. | | | |. | . ..|.|. | | || | || |.| . .
dstskycnlrvtlrktevfadyiirtfvmsqvgqteeryvyqyhftvwpdkgvpqyatavlglrrkitkdslpgarpwvihcsagvgrtgaflvidamlr
QLTRGKEPKISEIVRTIREQRPQSVDSYIQYVSLYMA
| . | | . |..|||.||. |.. ||| ...|
qakkqktvdifnyvkairedrphmvqtseqyvfihla
|
|||||||||
| subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 159-388 | 7.9e-14 | 46.4 | In-house | 9-236 (239) | alignment | ||
Range on Protein: 159-388
Range on HMM: 9-236/239.0
SSRNRHNDSKCYDHNRIIVQMC----KDDYINGSKINVPHFTPSIYLVQLPKMDSvdAVEEFWRVVFHEQCQTVHIIARpeeLTNPaiDKLFCQEsgAWL
..||. . |||.|.... . |||| | . .| |. . . .|||....|. . ... | . | |.. |
kaknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcvei..ssgdfwrmmwqerrcvivmltg...lieg..hkkkchq..ywp
YANGFFVNTRKVEKKENAKADMFVVELLPE--GCSNAVMCSVYLHTYWKPLFGPDRFGAQIRAAHQIAKNE-NGNSPTVIASVNGSGRNAALLTLAVVED
. ..| | .| . || . .. | .. | | | |. | . ..|.|. | | || | || |.| . .
dstskycnlrvtlrktevfadyiirtfvmsqvgqteeryvyqyhftvwpdkgvpqyatavlglrrkitkdslpgarpwvihcsagvgrtgaflvidamlr
QLTRGKEPKISEIVRTIREQRPQSVDSYIQYVSLYMA
| . | | . |..|||.||. |.. ||| ...|
qakkqktvdifnyvkairedrphmvqtseqyvfihla
|
|||||||||
| subfamily_egg_pd | Subfamily egg | 159-409 | 2.7e-11 | 37.7 | In-house | 41-286 (307) | alignment | ||
Range on Protein: 159-409
Range on HMM: 41-286/307.0
SSRNRHNDSKCYDHNRIIVQMC----KDDYINGSKINVPHFTPSIYLVQLPKMdsvDAVEEFWRVVFHEQCQTVHIIARPEELTNPAIDKLFCQESGAWL
. | . .| | |. ... ||.| ... . | | | ..|..|||.|| |..| . ... | . ... . .
lekarskrvhckdssrvklelrrGqylddfihanrvkGkpllnefilaqaplk...ntvddfwrmvfqeevqyivmltsrkeserceyywpkaesdslvt
YANGFFVNTRKVEKKENAKADMFVVELlpEGCSnavMCSVYLHtYWKplfGPDRFGAQIRAAHQI-AKNENGNSPTVIASVNGSGRNAALLTLAVVEDQL
.. ... ||..| . . . | | .| .|. | .. ... .. | | |.|. ...| . |.|... . .|
vpGslrienlkvdskadplfrvtklkl..vGgd...deerfle.hwq...gdvnnssdvysplrvlrklrnlskpvvvqdilGvskaatlvaieiallsl
TRGKEPK--ISEIVRTIREQRPQSVDSYIQYVSLYMATNWLIKTKLPSGHEVVSKIKK
|| | . . | .| .|. ||.| ..|. .| .... . | .|. ..
lrGpitkslvlravvflrlrrrlsvesvllylfvyrlvlfffrdvigsakeldvdyer
|
|||||||||
| subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 159-394 | 3.7e-09 | 30.8 | In-house | 39-278 (287) | alignment | ||
Range on Protein: 159-394
Range on HMM: 39-278/287.0
SSRNRHNDSKCYDHNRIIVQMCK---DDYINGSKInvPHFT-PSIYLVQLPKMDSvdAVEEFWRVVFHEQCQTVHIIARPEELTNPAIDKLFCQEsGAWL
..||. | .|..|... |||| . . .| ... . . .| .|||.|.... .| ...| | . . | . . .
vkknryadvlPiddtrvllsaegelGsdyinanyv..asytddeafiaaqgPiaa..tvrdfwravletrsasvitmtreveearlkcykywPer.evPm
YANGFFVNTRKVEKKENAkADMFVVELLPEGCSN-AVMCSVYLHTYWKPLFGPD-----RFGAQIRAAHQIAKNENGNSPTVIASVNGSGRNAALLTLAV
|. | . ..|| . . |. . |. . | .. . | || ... ..|.. .. | |. | || ||.. |
rvGGysvvlldydikePe.ygvralrlidletrearvvkqldllswPdkvlaPtavglirfvldvkqhielardasevGPlvvhddvGiGrsGillatlv
VEDQLTRGKEPKISEIVRTIREQRPQSVDSYIQYVSLYMATNWLIK
. ..| . .. .| .||.| | . .|. || | |
lvsrledlGrvdvaavvirlreyraalvqavvqlrllyealvtyyk
|
|||||||||
| subfamily_Cele-PTP-10_pd | Subfamily Cele-PTP-10 | 159-386 | 5.8e-09 | 30.0 | In-house | 56-282 (305) | alignment | ||
Range on Protein: 159-386
Range on HMM: 56-282/305.0
SSRNRHNDSKCYDHNRIIVQ-MCKDDYINGSKINVPHFTPSIYLVQLPKMDsvDAVEEFWRVVFHEQCQTVHIIARPEELTNPAIDKLFCQESGAWLYA-
..||..| | |.. . .. ||| . .| ... .| ....||| .| ... . . .... || . . . | |
itknryqdvpcqdqsavkldkpspsdyihanyvgcpmipekrficaqgpld..qtidefwwmviqnkveqivmlcktvelgklkcaqywpaaqgeklelk
NGFFVNTRKVEKKENAKADMFVVeLLPEGCSNAVMCSVYlHTYWKPLfgPDRF--GAQIRAAHQIAKNENGNSPTVIASVNGSGRNAALLTLAVVEDQLT
.| |. | . |.. . || | || | | ||| ... . .. . | |. | || ..... . ....
sgivvenvsgskpmerdaeiqit.llnltysgdqkmsvr.hlqwtew..pdrgvppckltslellsairgskvpivvhcsagigrtgtivaieyilekia
RGKE-PKISEIVRTIREQRPQSVDSYIQYVSLY
|. | . |.|...|.|| |... .||. ..
enkpcppmpelvkalrdqrafsiqndvqylfih
|
|||||||||
| 0049772 | (Phosphotyrosine protein) phosphatases II | 159-395 | 5e-08 | 28.5 | In-house | 47-282 (314) | alignment | ||
Range on Protein: 159-395
Range on HMM: 47-282/314.0
SSRNRHNDSKCYDhNRIIVQM---CKDDYINGSKINVPhftPSIYLVQLPkMDSVdaVEEF----------WRVVF--HEQCQTVHI-------------
..||. | ..| || |.. |||| | .. . . | | .. . |. | ||.|. .. ....
rdknryldilpad.nrvilpglpvsgsdyinasyvdgf...lkfIatqgp.leit..vvdfreepvlyyngwrmvlrgdlnvrdivmsrdevladelsrL
--------IARPEELTnpaidklfcqesgawlyaNGFFVNTRKVEKkenakadmfvvELL--PEGCSNAVmcSVYLHTYWKPlFGPDrFGAQIRAAHQIA
. .. ... | . . . | | | || ..... ||.. . .... ...... ..
daAlgKtpllildgng..................neptaadlellk...........eelydpelferlg..ikylripvpD.gsap.lledfdeflefi
KNENGNSPTVIASVNGSGRNAALLTLAVVEDQLtrgKEpKISEIVRTIREQRP-----QSVDSYIQYVSLYMATNWLIKT
.. . ..|... | || . ....| . .| . . |... .|..|| .. ...||. ..| . ..|.
eeadkggpvlvHCkaGkgRtgtfvvaaylmkll...gv.sleealedvrlkRpinpnpgfieqleqyefilealleylkf
|
|||||||||
| 0041856 | (Phosphotyrosine protein) phosphatases II | 160-393 | 1.1e-12 | 43.4 | In-house | 3-171 (182) | alignment | ||
Range on Protein: 160-393
Range on HMM: 3-171/182.0
SRNRHNDSKCYDHNRiivqmcKDDYINGSKINVPHFTPSIYLVQLPKMDsvdAVEEFWRVVFHEQCQTVHIIArpEELTNPaidklfcqesgawlyangf
..||. | .|||.| |||| . . .. . . . | | .. |..|.| . .....|. .. ||| .|
dknrysdilpydhsr......dldyInanlylgslpatrfiatqgplls...tvadflrmlkelgittivnlt..eelywp...................
fvntrkvekkenakadmfvvellpegcsN--AVMCSVYLHTYWKPLFGPDrFGAQIRAAHQIAKnenGNSPTVIASVNGSGRNAALLTLAVVEDQltrgk
. . ||.. | || . .. ... . . |... | || ..| . ... .
............................ellerlgiqylylpwpDhgvpd.ldelldfieevle...eggpvlVHCsaGvgRtgtlvaaylmkkl.....
EPKISEIVRTIREQRPQSVDSYIQYVSLYMATNWLI
. . |.|...|..||..| . ||. |..| .|.
gvsleeavklvrsrRpgmvitpnqyfflqlallell
|
|||||||||
| subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 160-386 | 1.9e-12 | 41.9 | In-house | 5-232 (237) | alignment | ||
Range on Protein: 160-386
Range on HMM: 5-232/237.0
SRNRHNDSKCYDHNRIIVQMC--KDDYINGSKINVPHFTPSIYLVQLPKMDSvdAVEEFWRVVFHEQCQTVHIIARPEELTNPAIDKLFCQESGAWLYAn
.||. . ..|||.|.... . . |||| . .. || |. ..| . ..||..|. |.| . ... | . | . . |
iknrygnivaydhsrvvlkgagsgsdyinatylkgfdgtpkkyiaaqgples..scddfwqmvwqekcsvivmltgliegnelkchkywpstdqpaayg.
gffVNTRKVEKKENaKADMFVVELLPE---GCSNAVMCSVYLHTYWKPLFGPDRFGAQIRAAHQIAKNENG---NSPTVIASVNGSGRNAALLTLAVVED
| | . |||. .| | || . . | | | |.. | .| ..| .. . .| .| | || . .| . .
...vltvslkkkee.fsdytvrslllskrltlkevrlihqyqftswpdrgvpqqtaallrfrkniinrsphvsesgpwiihcsagvgrtgiflvidamlr
QLTRGKEPKISEIVRTIREQRPQSVDSYIQYVSLY
| | | . | .| |.|| ... ||| ..
qakekkvvdiynyvysieedrpyiiqtkdqyvfih
|
|||||||||
| subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 160-388 | 1.8e-11 | 37.8 | In-house | 45-271 (515) | alignment | ||
Range on Protein: 160-388
Range on HMM: 45-271/515.0
SRNRHNDSKCYDHNRIIV----QMCKDDYINGSKINVPHFTPSIYLVQLPKMDSVDaveEFWRVVFHEQCQTVHIIARPEELtnpaiDKLFCQESGAWLY
..||... || .|... . . ||.| |.|. . . | |. ||| .|||.|..|. |. .... .| || | .
kknryknilPydsvrvklevindnPhsdyfnasyipsfdndkayiasqgPnkasvd...dfWrlvlqenvttiamvtklkeg.....dkikcgkyWPdkp
ANGFFVNTRKVEK-KENAKADMFVVELLPEGCSNAVMCSVYLHTYWKPLFGPDRFGAQIRAAHQIAK-NENGNSPTVIASVNGSGRNAALLTLAVVEDQL
.. . ||| .| ... .| ... . | | | . . .. ... ... . | .| | || .... | .
gdsvkfGsikvelvsleactggikrkltvlkgddsrtvtqfhfteWPdkGvpkhtssllklikevkadhgqythpliihcsaGvGrtGvvisidsvvaha
TRGKEPKISEIVRTIREQRPQSVDSYIQYVSLYMA
.. . ..|. ||..||. | || .| |
kttrmvdvfnfvtnirqkrpylvqtqeqyafiyga
|
|||||||||
| 0036282 | (Phosphotyrosine protein) phosphatases II | 182-386 | 2.8e-11 | 38.9 | In-house | 2-163 (174) | alignment | ||
Range on Protein: 182-386
Range on HMM: 2-163/174.0
DDYINGSKINVPHFTPSIYLVQLPKMdsvdaveeFWRVVFHEQCQTVHIIARPEELTNPAIDKLFCQesgawlyangffvntrkvekkenakadmfvvel
.|||| | ... . || ... | | ||. .......|| ...|| . . ..
sdyinaspldlsyitprliagqgpla........fwemlkelgittvvmlleekelglykcinywpe.................................
lpEGCSNAVMCSVYLHTYWKPLFGPDRFG--AQIRAAHQIAKNeNGNSPTVIASVNGSGRNAALLTLAVVEDQLTrGKEPKISEIVRTIREQRPQSVDSY
. . ||.. | || ....... .. ... |... | || ..| . .. .| . .. ..||..| |||..| .
..lredlerlgiqylylpwpDhgvpdlsillefvkfveealse.dpggpvlVHCsaGvgRtGtlvaaylmlrgll.eslvdaldlvrelRlqrpgmvqtp
IQYVSLY
|| ||
sQyrfly
|
|||||||||
| 0043147 | (Phosphotyrosine protein) phosphatases II | 182-392 | 3.1e-11 | 38.8 | In-house | 5-160 (172) | alignment | ||
Range on Protein: 182-392
Range on HMM: 5-160/172.0
DDYINGSKINVPHFTPSIYLVQLPkmdSVDAVEEFWRVVFHEQCQTVHIIARPeeltnpaidklfcqesgawlyangffvntrkvekkenakadmfvvel
.|||| | ..... .... | | ...||| . ....... . .
sdyinasyldlyyipdrfiatqgp...lrntladfwrmlkelgithivnltel...............................................
LPEGCSNAVMCSVYLHTYWKPLFGPdRFGAQIRAAHQIAK--NENGNSPTVIASVNGSGRNAALLTLAVVEdqltrgKEPKISEIVRTIREQRPQSVDSY
| . . ||...| | . ... ..| . ... . |... . | || ..| . .. . .. |.|...||.||..| .
lydpellerlgiqylylpwpDhgvp.llellleflefidellalspggpvlVHCsaGvgRtgtlvaaylml......lglsleeavalvrekRpgavqnp
IQYVSLYMATNWL
|| ||. ..|
sqyrflyyfekll
|
|||||||||
| 0051429 | (Phosphotyrosine protein) phosphatases II | 182-395 | 1.4e-07 | 27.0 | In-house | 4-227 (272) | alignment | ||
Range on Protein: 182-395
Range on HMM: 4-227/272.0
DDYINGSKINVPhftP-----S-IYLVQLPKMDSvdaVEEFWRVvFHEQCQTVHIIARPEELTNPAIDKLFC----------QESGAWLYANGFFVNTRK
..||| . .. . .|. . | . ...||| .... |. . ..||. |.. .| . . ..| . .
sgyiNardvggy...grvvkpgrlyrsggplplt...aadfwrl.kelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtlls
VEKKENAKADMFVVELL-PEGCSNAVMCSVYlhTYWKPLFGPDRFgaqIRAAHQIAKNengNSPTVIASVNGSGRNAALLTLAVVEDQLTRGKEPK----
.| ... ......|| . | . ||. .| | | |. .... .. . . | .. | .| . . | . .... .
eellldyilrellltlllsagearevmhlhy..tdwpdhgvpqea...llellellld...ggpvlvHCsaGkdRTGtvvallllllgvsletivddYll
----ISEIVRTIREQRPQSVDSYIQYVSLYMATNWLIKT
. |.|. .|.|||..| .. ||. ||.| |...
tnlyleeaveelraqrpgavqteeqylflyeallellrs
|
|||||||||
| 0051082 | (Phosphotyrosine protein) phosphatases II | 190-388 | 5e-06 | 21.7 | In-house | 6-148 (151) | alignment | ||
Range on Protein: 190-388
Range on HMM: 6-148/151.0
INVPHFTPSIYLVQLPkmdsvdaVEEFWRVVFHEQCQTVHIIARPEELTnpaIDKLFCQESGawlyangffvntrkvekkenakadmfvvellpegcsna
|| |. .|. . | ..|.. . .....|. . .|| .. ...| |
infsyvtgglyrsggp.......ladflellkelgiktivnlrseeerg...ycpeylpelg......................................
vmcS--VYLHTYWKPLFGPDRFGAQIRAAHQIAKNeNGNSPTVIASVNGSGRNAALLTLAVVEDQltrgkePKISEIVRTIREQRPQSVDSYIQYVSLYM
.... | .| . . .......... . ..| |... | || ..| | . . . |... .|..|| .| . |.. ...
...ievlhipildwpdpglplsfdavleflellld.kkngpvlvHCsaGkgRTGtlvalylmllg......vsleealeeyrlkrpgvvqpnqqflfqlf
A
|
a
|
|||||||||
| subfamily_Cele-PTP-5_pd | Subfamily Cele-PTP-5 | 195-418 | 2.9e-36 | 118.8 | In-house | 113-335 (346) | alignment | ||
Range on Protein: 195-418
Range on HMM: 113-335/346.0
FTPSIYLVQLPKMDSVDAVEEFWRVVFHEQCQTVHIIARPEELTNPAiDKLFCQESGAWLYANGFFVNTRKVEKKENAKAdmFVVELLPEGCSNAVMCSV
| . ..|||.|.. ||.|| ....|| . |... . | | . || .| | . |. .|.| |. . . | . .|.|||| |..|.| |
fehklivaqlpqmenesfvedfwymiyqeqihlvylmvpddklkntt.tslfndenggyqytgkmfinnrradvsgdpke..ytievlpegnsdsvicqv
YLHTYWKPLFGPDRFGAQIRAAHQIAKNEN-GNSPTVIASVNGSGRNAALLTLAVVEDQLTRGKEPKISEIVRTIREQRPQSVDSYIQYVSLYMATNWLI
. |. || | | . |. ||. ... | . |. |.|| ... .|| | || | ||...|..||| .|.|. || |.| |
hhhapwkhlqqppktlpiikmihqflsekqvqnagvcvvslfgcgracsfigalyainqlnngiepniceimknikqqrpggvesfaqyasiyaivfdyi
KTKLPSGHEVVS-KIKKFNEKATRSL
| .. | .|..| .. . .
arkrggkkapvnkdinrfidelaeis
|
|||||||||
| 0046846 | (Phosphotyrosine protein) phosphatases II | 195-394 | 3.8e-11 | 38.5 | In-house | 15-174 (176) | alignment | ||
Range on Protein: 195-394
Range on HMM: 15-174/176.0
FTPSIYLVQLP---KMDSVDAVEEFWRVVFHEQCQTVHIIARPEELTNPAIDKLFCQESGAWLyangffvntrkvekkenakadmfvvellpegcsnavm
.....| .| . .. ...|.. ........| . . || .. .. .. .. .
inanlilgsrpiatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpeleklgi.....................................
csVYLHTYWKPLFGPDRfGAQIRAAHQIAKNENGNSPTVIASVNGSGRNAALLTLAVVEDqltrGKEPKISEIVRTIREQRP-QSVDSYIQYVSLYMATN
|||. | || . ... .| . . . |... . | || ..|. . .| .| .. |.....||||| ..| . || ||..
..qylhlpwpDhgvpdl.elllellefirealkeggpvlVHCsaGigRtgtlvaayllel....ekglsveealalvreqRplgavqtpeQyrflyefel
WLIK
.|.|
lllk
|
|||||||||
| 0049260 | (Phosphotyrosine protein) phosphatases II | 213-387 | 2.2e-09 | 32.7 | In-house | 22-144 (152) | alignment | ||
Range on Protein: 213-387
Range on HMM: 22-144/152.0
VEEFWRVVFHEQCQTVHIIARPEELTNPAIDKLFcqesgawlyangffvntrkvekkenakadmfvvellpegcsnavmcsVYLHTYWKPLFGPDRFGAQ
...||| . . ...|. . ...||. . .... |||..| ||
ladfwrmlkelgittivmltellelgklkceqyi...............................................qylhlpwpDhgvpdlsqll
IRAAHQIAK-NENGNSPTVIASVNGSGRNAALLTLAVVEdqltrgKEPKISEIVRTIREQRPQSVDSYIQYVSLYM
. . . | | ... . |... . | || ..| . .. . .. |.|. .||.||..| . |. ||
lflllfieklaldkggpvlVHCsaGvgRtgtlvaaylml......lgvsleeavalvrekRpgavpnpgqlrflye
|
|||||||||
| subfamily_Cele-PTP-17_pd | Subfamily Cele-PTP-17 | 245-397 | 6e-13 | 43.0 | In-house | 180-342 (347) | alignment | ||
Range on Protein: 245-397
Range on HMM: 180-342/347.0
LFCQESGAWLYANGFFVNTRKVEKKENAKADM--FVVELLPEGCSNAVMCSVYLHTYWKPLFGPDR---FGAQIRAAHQIAK-----NENGNSPTVIASV
.| |. .| .|...|||.|| . .|. | . ||.. ||||.| .. || | | || | .|| . . | . .| |.
ffpletdhylnlkgwlintravevdqrnknwmnkytvevvaegcseatfakvyncttwpwkkypddekkvlalvrapvkesstslianleklapvvvmcd
NGSGRNAALLTLAVVEDQLTRGKEPKISEIVRTIREQRPQSVDSYIQYVSLYMATNWLIKTKL
| | |... ... .|. || | .. . .|.|| | | |. . .| ||
lgldrsatvvltsiiieqvldgktpdcddlfkkmrdqragvftmsifytyairaalfylklkl
|
|||||||||
| 0048076 | (Phosphotyrosine protein) phosphatases II | 277-392 | 6.2e-06 | 21.5 | In-house | 34-142 (145) | alignment | ||
Range on Protein: 277-392
Range on HMM: 34-142/145.0
FVVELLPEGCSNAVMcsVYLHTYWKPLFGPDRFGAQIRAAHQIAKNENGNSPTVIASVNGSGRNAALLTLAVVEDqltrgKEPKISEIVRTIREQRPQSV
. . .|.... .. ||.. | || . ... ..| . . . |... | || ..| . .. . . |... .|.|||..|
lnltselellerlgi..qylylpwpDhgvpdllellleflefieealkeggpvlVHCsaGvgRtgtlvaaylmll.....lgvsleealelvrsqrpgav
DSYIQYVSLYMATNWL
. |. ||.. .|
pnpgqlrflyefelel
|
|||||||||
| 0048179 | (Phosphotyrosine protein) phosphatases II | 278-389 | 6.9e-06 | 21.4 | In-house | 33-141 (144) | alignment | ||
Range on Protein: 278-389
Range on HMM: 33-141/144.0
VVELLPEGCSNAVMCS--VYLHTYWKPLFGPDRFGAQIRAAHQIAKNENGNSPTVIASVNGSGRNAALLTLAVVEdqlTRGkePKISEIVRTIREQRPQS
|. | .| . . . |||. | || . ... . | . . . |... | || ..| .. .. ..| . |... .|..||..
vinlteeyepefleregiqylhlpwpDhgvpdllellleflefieealeeggpvlVHCsaGvgRtgtlvaaylmk...klg..lsleealalvrsrrpga
VDSYIQYVSLYMAT
| . |. |..
vpnpgqlrfLleye
|
|||||||||
| PTPc_DSPc_SM00012 | 292-389 | 1.1e-17 | 59.5 | In-house | 2-103 (105) | alignment | |||
Range on Protein: 292-389
Range on HMM: 2-103/105.0
CSVYLHTYWKPLFGPDRFGAQIRAAHQIAKNENGN---SPTVIASVNGSGRNAALLTLAVVEDQLTRG-KEPKISEIVRTIREQRPQSVDSYIQYVSLYM
...| .| |. |.. . ... ... ||.| . .|.|. . .| || . . .|... .||... ||..|..||. .|.|||..|... ||. ||.
vkhyhytgwpdhgvPeesdsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgmvqteeqylflyr
AT
|
al
|
|||||||||
| subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 325-388 | 2.9e-06 | 21.4 | In-house | 227-290 (297) | alignment | ||
Range on Protein: 325-388
Range on HMM: 227-290/297.0
GNSPTVIASVNGSGRNAALLTLAVVEDQLTRGKEPKISEIVRTIREQRPQSVDSYIQYVSLYMA
| .... | || .. |. ..| ... |.. |.. .||||.. | . |. || |
rnayllvhcsaGvGrsGvvvlsdvilaklrkkripdvaailsilreqrarlvqtleqfellyda
|
|||||||||