Gene unc-26 in Caenorhabditis elegans

Synonym: CELE_JC8.10, unc-26

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family Sac
Subfamily Synaptojanin
Protein sequence
ID Type Fasta BLAST phosphatome Note
CeleP194_AA protein Get Run
CeleP194_AA_178-476 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_FIG4_pd Subfamily FIG4 47-477 2.9e-54 175.4 In-house 58-539 (569) alignment 
Range on Protein: 47-477
Range on HMM: 58-539/569.0
DVERRSYQKIVDAYGILGVLAITKDeAVLVAVTGVLSVGQLYGADILKITNVEFISLRTFGSV---ENVDSRIIDL-QRLLSSQMFYFSslQSYDLTRSA
. .|  ..| | ||||||..  ..    |. ||   .|... |  | || ....|.. .  .       ..|   | . .  .. ||||   ||||||. 
eanrdglekkvsayGilGfvrfleg.yylilvtkrkkvaviGghaiykiedialikitedskksekssdearylklfkdvdltknfyfs..ysydltrtl

QHRDS------------HDC----------SDARFFWNRSLHFSFQRyGIDTDNWLLKCMAGSVLVRVVYVGANTGRVALISRLSCERVGTRFNVRGANY
|.  .            . .          .. .| ||  |   ..   ..| .|||. . | |    . | ...  |.||.| | .  |.||  ||.| 
qtnlllsdsnrekekaedrvditieakkldanekfvWnnflleplkd.tvktfdWlleiihGfvsqskisvlgksiyvtliarrsskfaGarflkrGvnn

LGNVANFVETEQLL-------LFDEKECSLLQIRGSIPLFWEQPGVNVG-SHKVKLRAFETSLPAYHRHLSQLQHRYGEFA-IVNLLGRKE---GERVLG
 |.||| |||||..       | ... .| .|.|||.||.|.|   ..    ..|.   .  . |  .|...| .|||    |.||. .||    |..| 
kGdvaneveteqivheasegsldsdryssfvqlrGsvPlyWsqdasklvtkPpikidvvdPfasaaalhfddlfqryGspiiilnlvkkkekrkresill

DAFKTQHK-SSHFAPL---VDFIDFDYHAQMKISKEAIVQ-LKKKMSPHMTKHGFFYSMGK-EIVKRQTGVIRTNCLDCLDRTNAVQTAIGLQMSHDQVA
 .|..  .   .| |    ...| .| . . | ..| ... |.|  .  ..| |.|.|. . | .|.|.|..||||.|||||||| | .|| .    |. 
eefeaaieylneflPeekklkyiswdmaraskskeenvlevlekyaeksvkktGiflsapdlestkiqeGivrtnCvdcldrtnaaqfvigkvalgyqlk

FLN-LNAGKVNVEQRVEEILRDLWQKNGDQCSTIYAGTGALDG----------KSKLKDASRSLARTIQNNLMDGAKQESFDLFLT
 |  ..  |....  | ..| .|... ||. .  |.|.   .           .|| .|  ..|.| . | ..|  ||.. .||| 
slGiidesklefdsdvvrlleelyedlGdtlalqygGsqlvntiktyrkiaqwssksrdiletlkryysnsfvdadkqdainlflG
Sac_COG5329 53-840 1.2e-122 402.0 In-house 55-849 (1070) alignment 
Range on Protein: 53-840
Range on HMM: 55-849/1070.0
YQKIVDAYGILGVLAITKDEaVLVAVTGVLSV-GQLYGADILKITNVEFISLRTFgSVENVDS-----RIID---------LQRLLSSQMFYFSSlqSYD
 .     ||.||.. .....  | ..||. .| .. .|  | || .|.||||.   . .. ..     ..           |. |||   ||||.   .|
lssaheiygvlGlielegsl.flivitgkskvaqvipgetiykilavdfislnnn.kwddeeiesdeasteklrsehpcselkkLlsngsFYfSt..dfd

LTRSAQHR------DSHDCSDARFFWNRSLHFSFQRYGIDTD--------N--WLLKCMAGSVLVRVVYVGANTGRVALISRLSCERVGTRFNVRGANYL
.| . |.|       |.|..| .|.||. |   .  |  . .        |  .|  .  | .   ...|...| . .||||.| .|.||||. || .  
itntLqkrlkeelelsvdtadeefmwnsflleelinyrsklsslekqlldnagFlttvIrGFaetvfikvkkktiaLtlISRrSskragtRflarGvDdd

GNVANFVETEQLLLFDEKECSLLQIRGSIPLFWEQPGVNVGSHKVKLRA-FETSLPAYHRHLSQLQHRYGEFAIVNLLGRKEGERVLGDAFKTQHKSSHF
||||||||||| .   ..  | .|.|||||.|||| . .  . |..    .| . .| ..| ..|  .||   |||||. |. |. |  ... . | | .
GnvanFVETEqIvyssqycfsFtQvRGSiPiFWeqesnsligpkiqitrsseatqsafdkHFdklfekYGdvhivNLlktKssEieLseryekhlklsek

APLvDFIDFDYHAQMKI-SKEAIVQLKKKMSPHMTKHGFFY--SMGKEIVKRQTGVIRTNCLDCLDRTNAVQTAIGLQ------MSHDQVAFLNLNagkv
 .. ... ||.|.. .  . ...  | ...   ..  |.|      ......|.||.||||||||||||..|. |...      .|...... . .    
pki.hlteFdfhketsqdgfddvkkLlplieqdllefgyfsydvkegkliseQdGVfRtNClDCLDRTNviQqliskrvlleqfrsikvisaidde....

nveqRVEEILRDLWQKNGDQCSTIYAGTGALDGK----------SKLKDASRSLARTIQNNLMDGAKQESFDLFLTGAAYDprlfdracnilppSLIQES
       ..|. ||  |||. | || ||||| ..          ..|.||. |  | ..|| .|. ||.. ||.|. . ..             . .. .
....dflqklneLWadnGDaisqiYTGtgalkssftrkgkrsiagalsDatkSvsRmyinnfvDkekQdaidllLgklpdq.............eavely

YYYHEYADAVSQlvERSPEIAEPQSIKIFVGTWNVNGgkNIHNvafrneSSLSHWIFAnsmtRLVSVEDEQLADIVAIGVEELVDLNASNMVKASTTNQR
   .|| . ...  ... |. . ....||..| |.||  ....       .|. . ..     |  . .. . ..|..  ..   | . . ...| . ..
dpineyvnlrlr..kseseftaaknvsiftltfnsng..esss......tkllklllk....vlekkisklvvgvvglqkqiwlelillssltksefkee

MWCESIRKTLSE-KAPFVLIGSEQLVGVCLFLFARPRVSPYLKDFAVASVKTGMGGATGNKGSVAFRIVVFSTSICFICSHFAAGQNEIRDRNEDFATTL
..  ..||  .. |   ... |.|| .. .. . .   . . .   .|  ||| ||  .||| |...  .. ....|  ...|........|| .     
eeenlvrkyenklkkkkleqsssqltalfilfkksadikevvssekaagrktgtgglnankgavkieaeseglvfifvdasaaledenesernskyesit

KKIRFPLGREIDSHDVIFWLGDFNYRINLSGDEVKNAVRNGDYAkLVENDQLTQQKALGQTFVGFNEGQLTFAPTYKYDTfSDDYDTSEKCRAPAWTDRI
|..... .  |  |..|.. ...|..|..  .||.... . ..  ...... .|.   . .. .. |..  . ...|..   ||.||... . .....|.
krvskeipkmikdhqlilldiainltidydeeevraekekeidr.elkkydtkqeltekvfvekvleptevpellekksy.eddndtdtedayrklrtrk

LWKDQRKKGKtqlLSYDRSELKTSDHRPVGAVFKVETFKV
| ... ||..   | |  .||| |||.|| | .|.. ...
liqkeekkte...laysslelkisdhkpvtaevkiavlsk
subfamily_Synaptojanin_pd Subfamily Synaptojanin 54-806 0.0 1201.1 In-house 1-753 (754) alignment 
Range on Protein: 54-806
Range on HMM: 1-753/754.0
QKIVDAYGILGVLAITK-DEAV--LVAVTGVLSVGQLYGADILKITNVEFISLRTFGSVEnvdSRIIDLQRLLSSQMFYFSSLQ----SYDLTRSAQHRD
||||||||.||||.... ||..  ||.|||. |||....|.|.|||..|..|||. .|.|   .|||.|..||.|..|||||..    ..||..|||.|.
qkivdaygllGvlrlnagdetlsflvlvtgcksvGkisdaeifkitstelvslrseasde...driielkkllasgtfyfsssadsasrldlslsaqrrk

SHDCSDARFFWNRSLHFSFQRYGIDTDNWLLKCMAGSVLVRVVYVGANTGRVALISRLSCERVGTRFNVRGANYLGNVANFVETEQLLLFDEKECSLLQI
.....|.|||||||||...||.|...|.||||.|.||| .|.||.||.. ..||||||||||.||||||||.|. |||||||||||..|.|.| .|..||
qeesednrffWnrslhlhlqrfgvncddWllkvmcGsveirtvyagakqakaalisrlsceraGtrfnvrGvndeGnvanfveteqvillddkvtsfvqi

RGSIPLFWEQPGVNVGSHKVKL-RAFETSLPAYHRHLSQLQHRYGEFAIVNLLGRKEGERVLGDAFKTQHKSSHFAPLVDFIDFDYHAQMKISKEAIVQ-
|||.||||||||..|||||||| |.||.| .|..|||.||..||||..||||||.||||.|| .|||...|.|..|. |.|..||||...|..|..... 
rGsvPlfWeqPGlqvGshkvklsrgfeasaaafdrhleqlkeryGevvivnllGskegeevlskafkkhlkasehakdvpfvkfdyhqkvkggkkeklek

-LKKKMSPHMTKHGFFYSMGKEIVKRQTGVIRTNCLDCLDRTNAVQTAIGLQMSHDQVAFLNlNAGKVNVEQRVEEILRDLWQKNGDQCSTIYAGTGALD
 |||... ......||.|.|||..|.||||.|.||||||||||||||..||.....|...|. ...|..| .|.||....||.||||..|.||||||||.
llkkqlklflesasfflskgkevekeqtGvlrvnClDCldrtnavqtvlglevlekqlealk.lsskesvvsrfeevfkslWsknGdeiskiyaGtgale

GKS---KLKDASRSLARTIQNNLMDGAKQESFDLFLTGAAYDPRLFDRACNILPPSLIQesyyyhEYADAVSQLVERSPEIAEPQSIKIFVGTWNVNGGK
||.   ||||..||.|||||||..|..|||..||.|.|..|. .|.|.|...|..||..      ..|.....||||. |..|.....|.||||||||||
gkakvsklkdgarsvartiqnnfldsskqeaidllllgntyveeladkarallkssllr......asakilkelvereqelteakklricvgtwnvnggk

NIHNVAFRNEsSLSHWIFAnsMTRLVSVEDEQLADIVAIGVEELVDLNASNMVKASTTNQRMWCESIRKTLSEKAPFVLIGSEQLVGVCLFLFARPRVSP
....||..|| ||..|...  ...|...||...|||.|||.||||||||||.|.|||||...|.|...|.||..|..||..||||||||||.|.||...|
qlrsvalkne.sltdwlld..lpelsgaedskpadiyaiGfeelvdlnasnlvsasttnrkewaeelqkvlsrdakyvlltseqlvGvclfvfvrpklvp

YLKDFAVASVKTGMGGATGNKGSVAFRIVVFSTSICFICSHFAAGQNEIRDRNEDFATTLKKIRFPLGREIDSHDVIFWLGDFNYRINLSGDEVKNAVRN
...|.||..||||.|||.||||.||.|....|||.||||||.||||.....||||.|.. .||.||.||...|||..||||||||||.|. ||||..|..
firdvavstvktGlgGaaGnkGavairlllhstslCfiCshlaagqskvkernedyaeiarkiafpmgrtleshdyvfWlGdfnyridlekdevkelvkk

GDYAKLVENDQLTQQKALGQTFVGFNEGQLTFAPTYKYDTFSDDYDTSEKCRAPAWTDRILWKDQR
 ||.|||||||||.||. |..| ||.||.||||||||||.||||||||||.|.||||||.||....
kdydklvendqltkqkkkgkvfkgfaegeltfaPtykydlfsddydtseklrvPaWtdrvlwrrkk
subfamily_SAC1_pd Subfamily SAC1 55-478 3.7e-91 297.1 In-house 3-452 (458) alignment 
Range on Protein: 55-478
Range on HMM: 3-452/458.0
KIVDAYGILGVLAITKDEAvLVAVTGVLSVGQLYGADILKITNVEFISLRTFGS--VE---NVDSRII-DLQRLLSSQMFYFSSlqSYDLTRSAQH----
..|. .||||.. . . .  |. .| . .||.. |  | ....|| |.. .     .|   . ... .  |. .|.|. ||||    ||||.| |.    
evvkiagilGiikLlsgky.livitkkeevgringkviyrvadveiipvkknslslteeqkkeekeylkllelvlksetfYfsy..tydltnslqrlekv

-------RDSHDCSDARFFWNRSLHFSFQRyGIDTDNWLLKCMAGSVLVRVVYVGANTGRVALISRLSCERVGTRFNVRGANYLGNVANFVETEQLLLFD
       |.. .  | |||||. |  ....   . ....|  . | . .. . . |.. . .|||| |. |.|||..|||..  |||||||||||.....
tsaalkerslleradeRffwnkhlledlrk.epelesfilPvikGfikikelslnakeikfilisRRsifRaGtRyfvRGvdkeGnvanfvEtEqiveae

EKECSLLQIRGSIPLFWEQPGVNVGSHKVKLRAFETSLPAYHRHLSQLQHRYGEFAIVNLLGRKEGERVLGDAFKTqHKSSHFAPLVDFIDFDYHAQMKI
..  | .|.||||||.|.| .      ||||   | || | ..||......|||  .|||. .|  |  ||.|...   ... .. .... ||.| . . 
kaltsFvqvRGsiPllWsqkpnLkykPkvklsesedsldafkkhldeqielygenvlvnLvdqkGsEkklgeayes.vvralnkkkikyvafDFHkeCrk

SK-EAIVQLKKKMSPHMTKHGFFYS-MGKEIVKRQTGVIRTNCLDCLDRTNAVQTAIGLQMSHDQVAFLNLN--AGKVNVEQRVEEILRDLWQKNGDQCS
 . . .  |........ . |.|.    |.|||.|.||.||||.||||||| ||. .. .. ..|.. |..     |.. ....|.. ..|| .|.|..|
mrwdrlklLidqlekelsqegyflkseekkivkeqkgvvRtnCiDcLDRtnvvqsllarevLqkqleslgvlateskledsaeletsfknlwadnadavs

TIYAGTGALD------GKS----KLKDASRSLARTIQNNLMDGAKQESFDLFLTG
. |||||||       ||      |.|   |. | ..|| .|| .|.|.|||| .
vqYaGtgAlKtDftRtGkrtllGalrDgvnsvsryyknnfldgerqdsidLflgk
Syja_N SacI homology domain 59-338 2.7e-71 231.3 Pfam-A 1-315 (319) alignment 
Range on Protein: 59-338
Range on HMM: 1-315/319.0
AYGILGVLAITKdEAVLVAVTGVLSVGQLYG-ADILKITNVEFISLRTFGSVEN------------VDSRIIDLQRLLSSQMFYFSslQSYDLTRSAQHR
||||||.. ... | .|. .|.  .|....|  .| ||..||||.|..  . ..            ..  .  |..||||. ||||  ..||||||.|..
aygilGlirlls.esyllvitkrekvakirgehpiykiksvefiplnseeeessaieeekeeeekeeekllkllkkllssgsfYfS..ydyDltrslqrk

DSH---------------DCSDARFFWNRSLHFSFQRYGIDTDNWLLKCMAGSVLVRVVYVG-ANTGRVALISRLSCERVGTRFNVRGANYLGNVANFVE
 ..               .  | ||.||| |.  ......|...||| .. | |  | ..|   .. ...|||| |..| |||.. ||..  ||||||||
sekeeeekeeeskslpllkevderFvWNrnllkplielkldlsrwllpliqGfveqrsievkskkkveltLIsRrsvkraGtRylrRGidddGnvANfvE

TEQLLLF--D--EKECSLLQIRGSIPLFWEQ-PGVNvGSHKVKLR-AFETSLPAYHRHLSQLQHRYGEFAIVNLLGRKEGERVLGDAFKTQHKSS----H
|||.. .  .  .. .|..|||||.|||||| ....  ..|.|.    |.| .| ..|...|..|||.  .||||..|..|. |..|.... ..     .
tEqivsekkeeskrvfSfvqiRGSvPlfWeqasnls.lkpkikitrsseasqkafkkHfkklikrYgkivvvnLlekkgrEkkLseayeelinklnkklk

FAPLVDFIDFDYHAQMKIS
    ...|.||.|...| .
ekkklkyiefDfhkeckgk
Syja_N SacI homology domain 59-338 2.7e-71 231.3 In-house 1-315 (319) alignment 
Range on Protein: 59-338
Range on HMM: 1-315/319.0
AYGILGVLAITKdEAVLVAVTGVLSVGQLYG-ADILKITNVEFISLRTFGSVEN------------VDSRIIDLQRLLSSQMFYFSslQSYDLTRSAQHR
||||||.. ... | .|. .|.  .|....|  .| ||..||||.|..  . ..            ..  .  |..||||. ||||  ..||||||.|..
aygilGlirlls.esyllvitkrekvakirgehpiykiksvefiplnseeeessaieeekeeeekeeekllkllkkllssgsfYfS..ydyDltrslqrk

DSH---------------DCSDARFFWNRSLHFSFQRYGIDTDNWLLKCMAGSVLVRVVYVG-ANTGRVALISRLSCERVGTRFNVRGANYLGNVANFVE
 ..               .  | ||.||| |.  ......|...||| .. | |  | ..|   .. ...|||| |..| |||.. ||..  ||||||||
sekeeeekeeeskslpllkevderFvWNrnllkplielkldlsrwllpliqGfveqrsievkskkkveltLIsRrsvkraGtRylrRGidddGnvANfvE

TEQLLLF--D--EKECSLLQIRGSIPLFWEQ-PGVNvGSHKVKLR-AFETSLPAYHRHLSQLQHRYGEFAIVNLLGRKEGERVLGDAFKTQHKSS----H
|||.. .  .  .. .|..|||||.|||||| ....  ..|.|.    |.| .| ..|...|..|||.  .||||..|..|. |..|.... ..     .
tEqivsekkeeskrvfSfvqiRGSvPlfWeqasnls.lkpkikitrsseasqkafkkHfkklikrYgkivvvnLlekkgrEkkLseayeelinklnkklk

FAPLVDFIDFDYHAQMKIS
    ...|.||.|...| .
ekkklkyiefDfhkeckgk
subfamily_INPP5F_pd Subfamily INPP5F 117-852 8.1e-176 577.8 In-house 127-848 (951) alignment 
Range on Protein: 117-852
Range on HMM: 127-848/951.0
IDLQRLLSSQMFYFSSlqSYDLTRSAQHRDSH--DCS----DARFFWNRSLHFSFQRYGIDTD-NWLLKCMAGSVLVRVVYVGANTGRVALISRLSCERV
 .|..|||.. ||.|.  ..|||.. |.|  .  . |    | |||||. |   .  |   .| ..|.  . | | ......  ..  ..|||| | .| 
eelkkllsdgsFYysl..dfDltntlqkrgleeksestddwderFfWNkfllkdlinyrdkldkefltpviqGfvetkeisieklkvsltlisrrSrkra

GTRFNVRGANYLGNVANFVETEQLLLFDEKECSLLQIRGSIPLFWEQPGVNVGSHKVKLRAFETSLPAYHRHLSQLQHRYGEFAIVNLLGRKEGERVLGD
||||. || .  ||||||||||..| . ..  | .|||||.|.||||.|  . ..    | .| . ||...|.... ..||. .|||||  |. |. |..
gtrfkrrGidddgnvAnfvEtElilsvekyvlsftqirGSvPvfweqsgkkykpkikitrseeetqpaFdehfkeqlkkygkvvivnllsqkssekklsk

AFKTQHKSSHfAPLVDFIDFDYHAQMKISK-EAIVQLKKKMSPHMTKHGFFYSMGKE-IVKRQTGVIRTNCLDCLDRTNAVQTAIGLQMSHDQVAFLNLN
|.|.| . ..  . | .| ||.| . .  | |.. .| ...  .... |.|    || .. .|.||.|||||||||||| ||.||.... . |.  |.| 
aykeqllkle.skdvflikfdfheetsgekfenvsklielikneikevgyfsydvkekviseqkgvfRtnclDcldrtNvvqqaiskavlelqleklglf

AGKVNVE-QRVEEILRDLWQKNGDQCSTIYAGTGALDGK------S----KLKDASRSLARTIQNNLMDGAKQESFDLfltgaaydprlfdraC-NILPP
 ..  .. ... . | .||. |||. |..|||| || |.      .     |||.  |. |  .||..|  .|.  ||                   || 
epessiddeellqklkklWadngdaisrqYagtnalkgdltrkgerklaGvlkdgyksvsryylnnfkdkyrqkvidl...............llGklpk

SLIQE------------SyyyheyadavsqlVERSPEIAEPQSIKIFVGTWNVNGGKNihnvafrnESSLSHWIFAnsmtrlvsVEDEQLADIVAIGVEE
  ..|            .              |.. .  | . | ..||. ||||  .        .. ||.. |         . .   .|.| .|..|
qevvelidpkkeekeeel.............rekeekftetsninllvgsvnvngssk........kadlskllfp........igekfkpDlvvlGLqE

LVDLNASNMVKASTTNQRMWCESIRKTLSEK---APFVLIGSEQLVGVCLFLFARPRVSPYLKDFAVASVKTGMGGATGNKGSVAFRIVVFSTSICFICS
 |.| | ... | .. ...| . . ..| .      .... ||||... | ||.|     ..|.  .. .|||.|| .||||.|| |.    || ||. |
vvELtaGsiLaaDyskskfWEklvedlLnkvsreekYlkLrseqlsslLlllfvredkakkvkevegdtkktGfgGlagnkGavavrfeysatsFcfvns

HFAAGQNEIRDRNEDFATTLKKIRFPLGREIDSHDVIFWLGDFNYRINLSGDEVKNAVRNGDYAKLVENDQLTQQKALGQTFVGFNEGQLTFAPTYKYDT
|.|||.. . .| .|. .  ..|.|. ...|  || ||||||.||||.|. .||.  ... ...|| | ||||..   |. | ||.|  | | |||||| 
HlaAGasnveeRrsDykeiarsitFsrskrikdhDsifWlGDlnyRidlpneevRRelldqeidkLleyDqLtkeieaGevFegfkEetlkFrPtYkyDl

FSDDYDTSEKCRAPAWTDRILWKDQRkkgKTQLLSYDRSELKTSDHRPVGAVFKVETFKVGGRKCVELIEDV
 ...|||||| |.|||||||..|..      .|  | . |.. |||||| |.|...  .|  .|   | . .
gtknYDtsekeRtPaWtDRiiykgev...ledLeyysdaeilisDHrPvyaafrakvtvvDekkkltLkkkl
Exo_endo_phos Endonuclease/Exonuclease/phosphatase family 532-826 2.7e-27 86.1 Pfam-A 1-249 (249) alignment 
Range on Protein: 532-826
Range on HMM: 1-249/249.0
GTWNVNGGKNIHNVafrnesS-----LSHWIFANSmtrlvsvedeqlADIVAigVEELVDLnasnmvkastTNQRMWCESIRKTL---------------
.||||.|... ..       .     |  .. ...            .|...  . | ..            .. .. .. .. |               
ltwNvlgwnarsdr......akkldqladllqsed............pDvll..LQEvded..........plsellatglaselgldgdgksggggggd

SekapfvligseqlVGVCLFLFARPRVSPYLKDFAVASVKTGMG---GATGNKGSVAFRIVvfSTSICFICSHFAAGQNEIRDRNEDFATTLKKIRFPLG
.             .| .| |...  .. . ..  .  .|.| .   . .||||.|. |.   .........|...|. . . . . ... ..|.. . .
a.............gggglallskypldkkirrtfqldgkagiavprlssgnkgdvpvrfr..gktlalvntHltpgnrlrqrderallaeidkladdsr

REidshdVIFWLGDFNYRINLSGdevknavrngdyaklvendqltqqkalgqtfVGFNEGQLTFAPTYKYDTFSDDY-------------DTSEKCRAPA
        ....||||.|....                                 ||.|.  .|.|....| .....             ||.||.| ||
gs.....pvilaGDfNsrpdspd...............................kgfresaadflpgdgfddglrallphlllptspgttdtyekarepa

WTDRILWkdQRKKGKTQLLSYDRSELKT-SDH
..|.||.  ..   .... .... . .. |||
rlDyilv..ssgwpalvvsgasllsdrggSDH
DUF1866 Domain of unknown function (DUF1866) 835-949 6e-17 50.7 Pfam-A 2-119 (146) alignment 
Range on Protein: 835-949
Range on HMM: 2-119/146.0
VETFKVGGRKCVELIEDVVESMGPPDGTIIVSIAG-----KPRFPPQMFPPIHEKLKELGaQVQLSKFDDGDLWIVLNSGEMALAALSMDGLKIGGTdQI
|| ..|   .  .. ..|.   ||||.||.||.       |  |. ..   . ..| .|| .| | .| ......    || ||..||..| |. |  ..
veilevdpearravfkeviaaqGPpDativvslksgdedekeifdealieeLlqelaslG.eviLvRfvedkmlvtFrdgesALevlslkgikvlgr.al

NVKLKSPDWAYALKPHLSDF
...|||.||   |.  .   
kirlKskdWlksleeEivls