Gene VW02B12L.2 in Caenorhabditis elegans

Synonym: CELE_VW02B12L.2, VW02B12L.2

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family PTP
Subfamily CelePTP-sf5
Protein sequence
ID Type Fasta BLAST phosphatome Note
CeleP196_AA protein Get Run
CeleP196_AA_0-81 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_Cele-PTP-5_pd Subfamily Cele-PTP-5 1-116 7.8e-75 245.6 In-house 230-345 (346) alignment 
Range on Protein: 1-116
Range on HMM: 230-345/346.0
MIHQFHSEQQFRSLGMCVVSTFGSGRACTFIGALYAIHQLNNGVEPNIFEIMKTIKQQRPGAIESFPQYSGVYAIVLDYISRKRGGKSDPVNKYINRFLA
|||||.||.|....|.||||.||.||||.||||||||.|||||.||||.||||.|||||||..|||.||...||||.|||.||||||..||||.||||..
mihqflsekqvqnagvcvvslfgcgracsfigalyainqlnngiepniceimknikqqrpggvesfaqyasiyaivfdyiarkrggkkapvnkdinrfid

DLTEILPACSTLPVMN
.|.||.||||...||.
elaeispacsptkvmp
Y_phosphatase Protein-tyrosine phosphatase 1-77 6.1e-18 60.5 Pfam-A 158-234 (235) alignment 
Range on Protein: 1-77
Range on HMM: 158-234/235.0
MIHQFHSEQQFRSLGMCVVSTFGSGRACTFIGALYAIHQLNNGVEPNIFEIMKTIKQQRPGAIESFPQYSGVYAIVL
.|........ .|  ..|..  |.||..||. . ....||... |.....|.|....||||...|. ||  .|...|
lirkvekskeaksgpvvVhCsaGvgRtgtfvaldilleqleaeeevdvlqivkelRkqRpgmvqsleqYiflykail
Y_phosphatase Protein-tyrosine phosphatase 1-77 6.1e-18 60.5 In-house 158-234 (235) alignment 
Range on Protein: 1-77
Range on HMM: 158-234/235.0
MIHQFHSEQQFRSLGMCVVSTFGSGRACTFIGALYAIHQLNNGVEPNIFEIMKTIKQQRPGAIESFPQYSGVYAIVL
.|........ .|  ..|..  |.||..||. . ....||... |.....|.|....||||...|. ||  .|...|
lirkvekskeaksgpvvVhCsaGvgRtgtfvaldilleqleaeeevdvlqivkelRkqRpgmvqsleqYiflykail
DSPc_SM00195 1-80 7.1e-18 60.2 In-house 183-262 (263) alignment 
Range on Protein: 1-80
Range on HMM: 183-262/263.0
MIHQFHSEQQFRSLGMCVVSTFGSGRACTFIGALYAIHQLNNGVEPNIFEIMKTIKQQRPGAIESFPQYSGVYAIVLDYI
..........  |  ..|..  | ||..||. . .....|... ...||||.| ...||||..... ||. .| ..|.||
llravkkskstssgpivVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaileyi
PTPc_SM00194 1-80 7.1e-18 60.2 In-house 183-262 (263) alignment 
Range on Protein: 1-80
Range on HMM: 183-262/263.0
MIHQFHSEQQFRSLGMCVVSTFGSGRACTFIGALYAIHQLNNGVEPNIFEIMKTIKQQRPGAIESFPQYSGVYAIVLDYI
..........  |  ..|..  | ||..||. . .....|... ...||||.| ...||||..... ||. .| ..|.||
llravkkskstssgpivVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaileyi
subfamily_PTPN12_pd Subfamily PTPN12 1-83 4.7e-09 30.6 In-house 195-280 (290) alignment 
Range on Protein: 1-83
Range on HMM: 195-280/290.0
MIHQFHSEQQFRSLGMCVVSTFGSGRACTFIGALYAIHQLNNGVEP---NIFEIMKTIKQQRPGAIESFPQYSGVYAIVLDYISRK
.|..... |.  .  ..|    | ||. | |   |. ..|...  |   ..|... ....||. .. .  ||. ||  |.......
lielvrelqesedaPlvvhCsaGvGrtGtiiaidyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavaelvqke
0051299 (Phosphotyrosine protein) phosphatases II 2-80 6.5e-16 54.1 In-house 208-286 (288) alignment 
Range on Protein: 2-80
Range on HMM: 208-286/288.0
IHQFHSEQQFRSLGMCVVSTFGSGRACTFIGALYAIHQLNNGVEPNIFEIMKTIKQQRPGAIESFPQYSGVYAIVLDYI
...... .. ..  ..| .  | ||..||| ......||... .....|..|....||||..... ||  || ..|.|.
lrlvrkalasgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlreqRpgmvqtpeqyrfvyealleyl
PTPc_DSPc_SM00012 2-77 1.9e-15 52.3 In-house 26-104 (105) alignment 
Range on Protein: 2-77
Range on HMM: 26-104/105.0
IHQFHSEQQFR--SLGMCVVSTFGSGRACTFIGALYAIHQLNNG-VEPNIFEIMKTIKQQRPGAIESFPQYSGVYAIVL
......... .  |  ..|..  | ||..||. . ....||...  |..||.|.| ...||||..... ||. .|...|
lravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgmvqteeqylflyrall
subfamily_Ptp69D_pd Subfamily Ptp69D 2-82 7.4e-10 33.4 In-house 208-288 (307) alignment 
Range on Protein: 2-82
Range on HMM: 208-288/307.0
IHQFHSEQQFRSLGMCVVSTFGSGRACTFIGALYAIHQLNNGVEPNIFEIMKTIKQQRPGAIESFPQYSGVYAIVLDYISR
|.| .. ...    . |    |.||. .|.     ..||..  . .|||..| ...||.  ..|. ||. .|  .|||.| 
ieqvrelyklnrsPivvhCsaGvgrsgifvaldsllqqlkaedkvdifetvkdLrsqRnllvqsleqYvflyralldyssy
subfamily_Urchin-PTP-1_pd Subfamily Urchin-PTP-1 2-81 3e-07 24.6 In-house 199-278 (315) alignment 
Range on Protein: 2-81
Range on HMM: 199-278/315.0
IHQFHSEQQFRSLGMCVVSTFGSGRACTFIGALYAIHQLNNGVEPNIFEIMKTIKQQRPGAIESFPQYSGVYAIVLDYIS
|..  .... .   . |  . | ||.  .| .   . |....   ..|...|.....||  . .  .|. .| .||... 
ikevkadngkkefsllvhcsaGvGrtGvvisidevvaqikrtrsvdvfnfvknlrakrpylvqteeeyafiydavledll
0037934 (Phosphotyrosine protein) phosphatases II 3-80 2.6e-11 39.0 In-house 163-242 (243) alignment 
Range on Protein: 3-80
Range on HMM: 163-242/243.0
HQFHSE-----QQFRSLGMCVVSTFGSGRACTFIGALYAIHQLnngvEPNIFEIMKTIKQQRPG-AIESFPQYSGVYAIVLDYI
..| .|     .  ..  ..|  . | ||. |.| |.. ...|    . ...|..|....|||| |.... ||  .| ..| ..
refieellsllaldsggpvlVHCsaGvgRtGtliaaylmllll....gvdleeavkllreqRpgkavqtpsqyrflyeallell
subfamily_Anemone-PTP-6_pd Subfamily Anemone-PTP-6 4-82 4e-07 24.4 In-house 203-282 (318) alignment 
Range on Protein: 4-82
Range on HMM: 203-282/318.0
QFHSEQ-QFRSLGMCVVSTFGSGRACTFIGALYAIHQLNNGVEPNIFEIMKTIKQQRPGAIESFPQYSGVYAIVLDYISR
| .. | .     . |  . | ||. .||     ......    ..|...|....||.  .    ||  .| ..|...  
qvskaqqksgagpivvhCsaGvGrtGvfiavdillerikaealvDvfqtvkqlreqrnlmvqtedqyefiydvllealas
0043336 (Phosphotyrosine protein) phosphatases II 5-80 5.4e-15 51.1 In-house 202-277 (278) alignment 
Range on Protein: 5-80
Range on HMM: 202-277/278.0
FHSEQQFRSLGMCVVSTFGSGRACTFIGALYAIHQLNNGVEPNIFEIMKTIKQQRPGAIESFPQYSGVYAIVLDYI
... .. ..  ..| .. | ||..|||.......||... .....|..|....|||||.... ||  .| ..|.|.
vrealedsngpvlVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqRpgavqtpsqyrflyealleyl
subfamily_PTPRA_pd Subfamily PTPRA 6-80 7e-08 26.7 In-house 221-295 (330) alignment 
Range on Protein: 6-80
Range on HMM: 221-295/330.0
HSEQQFRSLGMCVVSTFGSGRACTFIGALYAIHQLNNGVEPNIFEIMKTIKQQRPGAIESFPQYSGVYAIVLDYI
.. .|  .  . |  . | ||. |||     .....     ..||..| ...|||  . .  ||  .| ..|.| 
kklnqqsagpivvhcsaGvGrtGtfivldavlervkaerkvdvfefvkrlrlqrpqmvqtdeqyefiykvlleyy
subfamily_Urchin-PTP-8_pd Subfamily Urchin-PTP-8 6-78 1.6e-07 26.1 In-house 182-253 (284) alignment 
Range on Protein: 6-78
Range on HMM: 182-253/284.0
HSEQQFRSlGMCVVSTFGSGRACTFIGALYAIHQLNNGVEPNIFEIMKTIKQQRPGAIESFPQYSGVYAIVLD
.| .. |.  . |  . |.||. ..|     ......    ....... ..|||.  .... ||  .|. .|.
tskenhra.nivvhcsagvgrtgvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysalle
subfamily_Urchin-PTPRA_pd Subfamily Urchin-PTPRA 6-78 1.8e-07 25.8 In-house 218-289 (319) alignment 
Range on Protein: 6-78
Range on HMM: 218-289/319.0
HSEQQFRSlGMCVVSTFGSGRACTFIGALYAIHQLNNGVEPNIFEIMKTIKQQRPGAIESFPQYSGVYAIVLD
.| .. |   . |  . |.||. ..|     ......    ....... ..|||.  .... ||  .|. .|.
tskenhra.nivvhcsaGvGrtGvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysalle
subfamily_Nvec-PTP-2_pd Subfamily Nvec-PTP-2 7-81 2.4e-09 31.8 In-house 169-243 (250) alignment 
Range on Protein: 7-81
Range on HMM: 169-243/250.0
SEQQFRSLGMCVVSTFGSGRACTFIGALYAIHQLNNGVEPNIFEIMKTIKQQRPGAIESFPQYSGVYAIVLDYIS
|.||  .  . |  . | ||. .||     ...|..    ..|...|.....||.|.||  ||. || |.| .. 
sqqqagnaPvivqCsaGvgrsGafiaidavlerlkkekvvdvfkvikvlrkdrphavesleqyvfvyeiilkald
subfamily_PTPRD_pd Subfamily PTPRD 7-82 1.1e-08 29.2 In-house 208-283 (564) alignment 
Range on Protein: 7-82
Range on HMM: 208-283/564.0
SEQQFRSLGMCVVSTFGSGRACTFIGALYAIHQLNNGVEPNIFEIMKTIKQQRPGAIESFPQYSGVYAIVLDYISR
. ..  .  . |    | ||  |||   . . ....    .|....|....||.  ...  ||. .. ..|.... 
alnepdagPivVhCSaGVGRTGtfividamlerikeektvDiyqyvkalrkqRnamVqteeQYiFiheailealac
subfamily_PTPRK_pd Subfamily PTPRK 7-79 6e-06 20.3 In-house 204-276 (314) alignment 
Range on Protein: 7-79
Range on HMM: 204-276/314.0
SEQQFrSLGMCVV-STFGSGRACTFIGALYAIHQLNNGVEPNIFEIMKTIKQQRPGAIESFPQYSGVYAIVLDY
. |.  . |  ||  . |.||. |||     .  ...    ..|...||......  .|   ||  .| ..|. 
ksqee.eaGrivvhCsaGaGrtGtfiaidivldmieregvvdvfnavktlrsrkvnmveteeqykfiydvilea
subfamily_Anemone-PTP-2_pd Subfamily Anemone-PTP-2 8-81 1.3e-08 29.5 In-house 218-291 (298) alignment 
Range on Protein: 8-81
Range on HMM: 218-291/298.0
EQQFRSLGMCVVSTFGSGRACTFIGALYAIHQLNNGVEPNIFEIMKTIKQQRPGAIESFPQYSGVYAIVLDYIS
.||     . |    | ||. |||     . ....     .|...|.....||||...  ||. .| .||....
qqqagnkpvivqCsaGvgRsGtfiaidsvlervkkeqvvDvfqvvkvlRkkrpgavqteeqYvfiyeavleald
0040438 (Phosphotyrosine protein) phosphatases II 9-116 1.2e-18 62.9 In-house 205-310 (317) alignment 
Range on Protein: 9-116
Range on HMM: 205-310/317.0
QQFRSLGMCVVSTFGSGRACTFIGALYAIHQLNNGVEPNIFEIMKTIKQQRPGAIESFPQYSGVYAIVLDYIsrKRGGKSDPVNKYINRFLADLTEILPA
.. ..  ..| .. | ||..|||.|.....||. . .....|..|....|||||.... ||  .| ..|.|.  ||.... |........|  |... . 
ledpggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrflydalleyl..krkltlepaselklkllklliplald

CSTLPVMN
 ..|....
dvklkeke
subfamily_PTPN5_RR_pd Subfamily PTPN5_RR 9-82 2.7e-08 28.2 In-house 197-270 (274) alignment 
Range on Protein: 9-82
Range on HMM: 197-270/274.0
QQFRSLGMCVVSTFGSGRACTFIGALYAIHQLNNGVEPNIFEIMKTIKQQRPGAIESFPQYSGVYAIVLDYISR
.. .   . |  . | ||.  ||... |..||..    ....|.  ....| | ...  ||  .. ..  | .|
enaklapvvvhCsaGiGrtGcfiaisiavrqlreeivvdvlkivcnlrldrGGmvqtseqyelihralclylkr
subfamily_Anemone-PTP-5_pd Subfamily Anemone-PTP-5 9-81 1.7e-07 25.6 In-house 212-284 (319) alignment 
Range on Protein: 9-81
Range on HMM: 212-284/319.0
QQFRSLGMCVVSTFGSGRACTFIGALYAIHQLNNGVEPNIFEIMKTIKQQRPGAIESFPQYSGVYAIVLDYIS
..  |  . |    |.||  |||    .. ....    ..|....... ||.  ..   ||. .| ..|....
ektqsgPivvhCsaGvGRtGtfivldamlervkeegvlDvfstvsrlRtqRnimvqrpeqYkfiyealleave
0046845 (Phosphotyrosine protein) phosphatases II 11-84 1.4e-16 56.1 In-house 202-278 (284) alignment 
Range on Protein: 11-84
Range on HMM: 202-278/284.0
FRSLGMCVVSTFGSGRACTFIGALYAIHQLNNGV---EPNIFEIMKTIKQQRPGAIESFPQYSGVYAIVLDYISRKR
 ..  ..| .  | ||..||| . ....||...    .....|..| ...||||..... ||  || ..|.|...|.
pgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvqtleqyrfvyealleylklkl
0050432 (Phosphotyrosine protein) phosphatases II 12-83 3.6e-17 58.1 In-house 231-302 (308) alignment 
Range on Protein: 12-83
Range on HMM: 231-302/308.0
RSLGMCVVSTFGSGRACTFIGALYAIHQLNNGVEPNIFEIMKTIKQQRPGAIESFPQYSGVYAIVLDYISRK
..  ..| .  | ||..||| ......||. . ....||..|....||||..... ||  .| ..|.|...|
pggpivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkklReqRpgmvqtpeqylflyralleylklk
0039614 (Phosphotyrosine protein) phosphatases II 12-84 1.4e-15 53.0 In-house 221-293 (297) alignment 
Range on Protein: 12-84
Range on HMM: 221-293/297.0
RSLGMCVVSTFGSGRACTFIGALYAIHQLNNGVEPNIFEIMKTIKQQRPGAIESFPQYSGVYAIVLDYISRKR
..  ..| .. | ||..|||.|.....||. . .....|..|....|||||.... ||  .| ..|....||.
kggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavqtpsqyrflydallellkrkl
0045450 (Phosphotyrosine protein) phosphatases II 12-82 3.1e-15 52.2 In-house 233-306 (307) alignment 
Range on Protein: 12-82
Range on HMM: 233-306/307.0
RSLGMCVVSTFGSGRACTFIGALYAIHQLNNGVE---PNIFEIMKTIKQQRPGAIESFPQYSGVYAIVLDYISR
..  ..| .. | ||..|||.|.....||... .   ....|..|....|||||.... ||  .| ..|... .
kggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrflyeallelllk
0040439 (Phosphotyrosine protein) phosphatases II 12-81 2.7e-14 48.9 In-house 178-247 (249) alignment 
Range on Protein: 12-81
Range on HMM: 178-247/249.0
RSLGMCVVSTFGSGRACTFIGALYAIHQLNNGVEPNIFEIMKTIKQQRPGAIESFPQYSGVYAIVLDYIS
..  ..| .. | ||..|||.|.....||.   . ...|..|....|||||.... ||  .| ..|... 
kggpvlVHCsaGvgRtGtfiaaylmleqlekelgvdleeavkllrsqRpgavqnpeqyrflyeallelll
0041856 (Phosphotyrosine protein) phosphatases II 12-81 3.6e-08 28.7 In-house 108-172 (182) alignment 
Range on Protein: 12-81
Range on HMM: 108-172/182.0
RSLGMCVVSTFGSGRACTFIGALYAIHQlnngvEPNIFEIMKTIKQQRPGAIESFPQYSGVYAIVLDYIS
..    |  . | ||..|...| . ...     . ...|..|.....|||....  ||  .. ..|... 
eggpvlVHCsaGvgRtgtlvaaylmkkl.....gvsleeavklvrsrRpgmvitpnqyfflqlallelll
subfamily_Choan-PTP-2_pd Subfamily Choan-PTP-2 12-83 9e-07 23.1 In-house 196-267 (270) alignment 
Range on Protein: 12-83
Range on HMM: 196-267/270.0
RSLGMCVVSTFGSGRACTFIGALYAIHQLNNGVEPNIFEIMKTIKQQRPGAIESFPQYSGVYAIVLDYISRK
..  . |  . | ||. |.|   .|.. |.. .. .. .|.. ....|.  ..   ||  .|. |. |..|.
kaePllvHcsaGvgRtGtlialDiavrlLeetkkvdvlaiieelRkdRmalvqhpeqyeflykavveyaerr
subfamily_PTPN6_pd Subfamily PTPN6 12-84 2.2e-06 21.9 In-house 226-301 (306) alignment 
Range on Protein: 12-84
Range on HMM: 226-301/306.0
RSLGMCVVSTFGSGRACTFIGA---LYAIHQLNNGVEPNIFEIMKTIKQQRPGAIESFPQYSGVYAIVLDYISRKR
..  ..|  . | ||  |||     |  |..  . .. .| ...|....|| | .    ||  || ..  || .|.
eagpivvhCsaGiGRtGtfiviDillkliekkgldadidiqklvksvreqrsglvqteqqykfvykaikkyietkk
0042113 (Phosphotyrosine protein) phosphatases II 13-81 3.7e-14 48.2 In-house 176-244 (245) alignment 
Range on Protein: 13-81
Range on HMM: 176-244/245.0
SLGMCVVSTFGSGRACTFIGALYAIHQLNNGVEPNIFEIMKTIKQQRPGAIESFPQYSGVYAIVLDYIS
.  ..| .. | ||..|||.|.....||.   . ...|..| ...|||||.... ||  .| ..|....
ngpvlVHCsaGvgRtGtfiaaylmleqlekelgvsleeavkelrsqRpgavqtpsqyrflyeallellk
subfamily_Choan-PTP-1_pd Subfamily Choan-PTP-1 13-83 1.1e-06 23.0 In-house 208-279 (281) alignment 
Range on Protein: 13-83
Range on HMM: 208-279/281.0
SLGMCVVSTFGSGRACTFIGALYAIHQLNNG-VEPNIFEIMKTIKQQRPGAIESFPQYSGVYAIVLDYISRK
   ...    | ||. |.|.   .......   | .. .... ....|   . .  ||. || .|||.....
kaplvihCsaGvGrtGtyialDrlvkaveaeleeldvkavvaelrkernlmvqtvvqyefvykavldaldke
subfamily_Urchin-PTPRB-like_pd Subfamily Urchin-PTPRB-like 13-81 2.2e-06 21.9 In-house 212-280 (288) alignment 
Range on Protein: 13-81
Range on HMM: 212-280/288.0
SLGMCVVSTFGSGRACTFIGALYAIHQLNNGVEPNIFEIMKTIKQQRPGAIESFPQYSGVYAIVLDYIS
.  . |. . | ||. ||| .  .|.....    ....... ...||.  ..   ||  .| ..|. |.
tgpiivhCsaGvGrtgtFialdalidaveeedyiDvagtvaklRkqRallvqtlkqYefiyevllslie
subfamily_Urchin-PTP-6_pd Subfamily Urchin-PTP-6 14-81 6.3e-07 22.8 In-house 210-277 (515) alignment 
Range on Protein: 14-81
Range on HMM: 210-277/515.0
LGMCVVSTFGSGRACTFIGALYAIHQLNNGVEPNIFEIMKTIKQQRPGAIESFPQYSGVYAIVLDYIS
  . .  . | ||.  .| .   . . ...   ..|.... |.|.||  .    ||. .| .||... 
hpliihcsaGvGrtGvvisidsvvahakttrmvdvfnfvtnirqkrpylvqtqeqyafiygavledll
0036941 (Phosphotyrosine protein) phosphatases II 15-85 8.9e-17 56.8 In-house 209-282 (297) alignment 
Range on Protein: 15-85
Range on HMM: 209-282/297.0
GMCVVSTFGSGRACTFIGALYAIHQLN---NGVEPNIFEIMKTIKQQRPGAIESFPQYSGVYAIVLDYISRKRG
 ..| .  | ||..|||.| ....||.      ...|.|..|....|||||.... ||  .| ..|... .|. 
pvlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyeallellkkklt
0047943 (Phosphotyrosine protein) phosphatases II 15-80 1e-14 50.1 In-house 207-272 (273) alignment 
Range on Protein: 15-80
Range on HMM: 207-272/273.0
GMCVVSTFGSGRACTFIGALYAIHQLNNGVEPNIFEIMKTIKQQRPGAIESFPQYSGVYAIVLDYI
 ..| .  | ||..||| ......||. . .....|..| ...||||..... ||  .| ..|.|.
pvvVHCsaGvgRtgtfialdllldqlekeggvdvleavkllrsqRpgmvqtpeqyrflyealleyl
subfamily_CG7180_pd Subfamily CG7180 15-80 1.3e-11 38.7 In-house 225-290 (296) alignment 
Range on Protein: 15-80
Range on HMM: 225-290/296.0
GMCVVSTFGSGRACTFIGALYAIHQLNNGVEPNIFEIMKTIKQQRPGAIESFPQYSGVYAIVLDYI
 ..|||. |..|.  ....  .. ....  | ..|| .||....||. .|.  .|  .| ..|...
PvvvvssdGasRsGvylaidanlelvekeeevdvFeavktlrrsRpqLvenveeYkyiYdvlleav
subfamily_Sponge-PTP10_pd Subfamily Sponge-PTP10 15-81 6.8e-09 30.1 In-house 213-279 (287) alignment 
Range on Protein: 15-81
Range on HMM: 213-279/287.0
GMCVVSTFGSGRACTFIGALYAIHQLNNGVEPNIFEIMKTIKQQRPGAIESFPQYSGVYAIVLDYIS
 . |  . . ||. .|. |  .|.. ..    ..|...|  ..|.||..    || ... ||| |..
sivvhCsdtvGrsamfcaaattinkckteGviDvfqvlksqriqkpgsvqtveqykfindivleyld
subfamily_Sponge-PTP8_pd Subfamily Sponge-PTP8 15-81 8.9e-09 29.9 In-house 218-284 (305) alignment 
Range on Protein: 15-81
Range on HMM: 218-284/305.0
GMCVVSTFGSGRACTFIGALYAIHQLNNGVEPNIFEIMKTIKQQRPGAIESFPQYSGVYAIVLDYIS
 . |.   | ||. .||    |. .|..  . ..||..|.....|......  ||  .. .. ..| 
pllVhCsagvgRtGvfiavdialerlkkEevvdvfevlkqlRskrmkmvqtldqYvflhdaldelit
subfamily_Urchin-PTP-3_pd Subfamily Urchin-PTP-3 15-95 6.8e-08 27.0 In-house 223-301 (325) alignment 
Range on Protein: 15-95
Range on HMM: 223-301/325.0
GMCVVSTFGSGRACTFIGALYAIHQLNNGVEPNIFEIMKTIKQQRPGAIESFPQYSGVYAIVLDYISRkrGGKSDPVNKYI
 . |  . | ||. .||    |. .. .  . .||. .| ....||  .|.  ||. .|  . ...    |    ||. . 
pilvhcsaGvGrtGvfislysalakvieesrvdifgfvkklrkdrpsmvetvdqyiliyealveayms..gntdvpvssfe
subfamily_Urchin-PTP-5_pd Subfamily Urchin-PTP-5 15-81 1.6e-07 25.7 In-house 219-285 (297) alignment 
Range on Protein: 15-81
Range on HMM: 219-285/297.0
GMCVVSTFGSGRACTFIGALYAIHQLNNGVEPNIFEIMKTIKQQRPGAIESFPQYSGVYAIVLDYIS
 . |  . | ||.  ..  .  . . ..  | .||...| ..|.||  .    ||. || .||....
PllvhclaGvGrtgvlltidsvvaeakrekevdifglvkklrqerpylvqtkeqykfvyvavleall
subfamily_Cele-PTP-15_pd Subfamily Cele-PTP-15 15-80 1.7e-06 22.3 In-house 205-270 (285) alignment 
Range on Protein: 15-80
Range on HMM: 205-270/285.0
GMCVVSTFGSGRACTFIGALYAIHQLNNGVEPNIFEIMKTIKQQRPGAIESFPQYSGVYAIVLDYI
 .||  . | ||..||.|  ||  .. .  . ....|.. ..  |  |..|. |.  .| ....|.
picvhcsagvgrtatfvgidyatirimenpniemldivremramrfqavqshmqflflyvvlmeyf
subfamily_Cele-PTP-4_pd Subfamily Cele-PTP-4 16-83 6.6e-21 69.0 In-house 221-288 (302) alignment 
Range on Protein: 16-83
Range on HMM: 221-288/302.0
MCVVSTFGSGRACTFIGALYAIHQLNNGVEPNIFEIMKTIKQQRPGAIESFPQYSGVYAIVLDYISRK
. .||. |.||| .|. .  |...|..| |||| ||.|.|..||| |..|. ||  .| ..| || .|
tvivSknGaGRagafltlavaveklqkgkepnikeivksiRsqRpravdslkQyvslyialllyikkk
subfamily_PTPN9_pd Subfamily PTPN9 16-83 8.4e-08 26.6 In-house 226-293 (297) alignment 
Range on Protein: 16-83
Range on HMM: 226-293/297.0
MCVVSTFGSGRACTFIGALYAIHQLNNGVEPNIFEIMKTIKQQRPGAIESFPQYSGVYAIVLDYISRK
. |  . | ||. |||   ... .|..    ...| .|....||  .|    ||   |  ||.|  ..
ivvhcsaGiGrtGtfitldiclsrleevgtvdvvetvkllrtqrafsiqtpeqyefcylavleyalel
0043147 (Phosphotyrosine protein) phosphatases II 16-73 3.6e-07 25.6 In-house 103-154 (172) alignment 
Range on Protein: 16-73
Range on HMM: 103-154/172.0
MCVVSTFGSGRACTFIGALYAIhqlnNGVepNIFEIMKTIKQQRPGAIESFPQYSGVY
..|  . | ||..|.. |.. .     |.  ...|........||||.... ||  .|
vlVHCsaGvgRtgtlvaaylml....lgl..sleeavalvrekRpgavqnpsqyrfly
0036282 (Phosphotyrosine protein) phosphatases II 16-73 3.4e-06 22.4 In-house 107-163 (174) alignment 
Range on Protein: 16-73
Range on HMM: 107-163/174.0
MCVVSTFGSGRACTFIGALYAIHQLNngvePN---IFEIMKTIKQQRPGAIESFPQYSGVY
. |  . | ||. |...|.. ...|     ..   ..........||||..... ||  .|
vlVHCsaGvgRtGtlvaaylmlrgll....eslvdaldlvrelRlqrpgmvqtpsQyrfly
subfamily_Urchin-PTP-7_pd Subfamily Urchin-PTP-7 16-98 4.6e-06 20.8 In-house 215-295 (315) alignment 
Range on Protein: 16-98
Range on HMM: 215-295/315.0
MCVVSTFGSGRACTFIGALYAIHQLNNGVEPNIFEIMKTIKQQRPGAIESFPQYSGVYAIVLDYISrkRGGKSDPVNKYINRF
. |    | ||. |||     ..|..     ....... ..|.| .....  ||  .| ..|. .    |  |   . |..|.
ivvhcsaGvGrtGtfitldavldqaeaenaidvynfitgvrqnrikmvqvaeqyqfiydalletfv..cgdtsiaqdlylqry
0045098 (Phosphotyrosine protein) phosphatases II 17-83 2.1e-10 35.9 In-house 210-275 (278) alignment 
Range on Protein: 17-83
Range on HMM: 210-275/278.0
CVVSTFGSGRACTFIGALYAIHQLnnGVEPNIFEIMKTIKQQRPG-AIESFPQYSGVYAIVLDYISRK
 |    | ||..|...| . ...|  .   ...|. |....|||| |.... ||  .|  .|....|.
lVHCsaGvgRtGtlvaaylmlell..eggvdlleavkelrsqRpglavqnleqyrflyefllelllrg
subfamily_PTPRG_pd Subfamily PTPRG 17-83 2.6e-07 24.3 In-house 224-290 (563) alignment 
Range on Protein: 17-83
Range on HMM: 224-290/563.0
CVVSTFGSGRACTFIGALYAIHQLNNGVEPNIFEIMKTIKQQRPGAIESFPQYSGVYAIVLDYISRK
 |    | ||. |.|     ..|...    |.|...|.|. ||.  ...  ||  .. ..|. |. |
vvHcsaGvgrtGtyivldtllkqiqqenavnvfgflkhiraqRnflvqteEqYiflhdalleaiask
subfamily_PTPN14_pd Subfamily PTPN14 17-84 5.1e-07 24.0 In-house 233-300 (300) alignment 
Range on Protein: 17-84
Range on HMM: 233-300/300.0
CVVSTFGSGRACTFIGALYAIHQLNNGVEPNIFEIMKTIKQQRPGAIESFPQYSGVYAIVLDYISRKR
 |  . | ||.   | .   |. |... | .| ........||   .... ||  || ... |. . |
lvhCsaGvGrtGvlilsdlliatlehneeidikkvlarLreqrmllvqtlaqYkfvYkvlikylknsr
subfamily_Sponge-PTP1_pd Subfamily Sponge-PTP1 17-80 3.5e-06 21.2 In-house 196-259 (267) alignment 
Range on Protein: 17-80
Range on HMM: 196-259/267.0
CVVSTFGSGRACTFIGALYAIHQLNNGVEPNIFEIMKTIKQQRPGAIESFPQYSGVYAIVLDYI
 |  . | ||. ||. .   .... .    .||. .. |..||.| ...  .|  .. .. .| 
vvacsdGvGrsGtflvidsqleraktegvsdifdflrkirsqriglvdtkeryiyihellaeya
0048076 (Phosphotyrosine protein) phosphatases II 17-77 5.5e-06 21.7 In-house 85-140 (145) alignment 
Range on Protein: 17-77
Range on HMM: 85-140/145.0
CVVSTFGSGRACTFIGALYAIHqlnngVEPNIFEIMKTIKQQRPGAIESFPQYSGVYAIVL
 |  . | ||..|...|   ..        ...|... ...|||||.... |.  .|  .|
lVHCsaGvgRtgtlvaaylmll.....lgvsleealelvrsqrpgavpnpgqlrflyefel
0049772 (Phosphotyrosine protein) phosphatases II 19-84 4.9e-09 31.8 In-house 218-284 (314) alignment 
Range on Protein: 19-84
Range on HMM: 218-284/314.0
VSTFGSGRACTFIGALYAIHQLnnGVepNIFEIMKTIKQQRP-----GAIESFPQYSGVYAIVLDYISRKR
  . | ||..||. | | ...|  ||  .. |... ....||     |.||.. ||  .. ..|.|.....
HCkaGkgRtgtfvvaaylmkll..gv..sleealedvrlkRpinpnpgfieqleqyefilealleylkflk
subfamily_Sponge-PTP5_pd Subfamily Sponge-PTP5 20-78 2.8e-06 21.5 In-house 206-264 (283) alignment 
Range on Protein: 20-78
Range on HMM: 206-264/283.0
STFGSGRACTFIGALYAIHQLNNGVEPNIFEIMKTIKQQRPGAIESFPQYSGVYAIVLD
 . | ||. .||.|  .....      ..|...| ...||..|. .  ||  |. .||.
CstgiGrtavfiaasasvkdaltesvvdvfavvkimreqrmmavqtldqyklvhelvle
0051429 (Phosphotyrosine protein) phosphatases II 21-82 2.8e-07 26.0 In-house 158-227 (272) alignment 
Range on Protein: 21-82
Range on HMM: 158-227/272.0
TFGSGRACTFIGALYAIHQLNNGVEPN--------IFEIMKTIKQQRPGAIESFPQYSGVYAIVLDYISR
. | .|  |.. .|. .....  .  .        ..|... ...|||||...  ||  .| ..|... .
saGkdRTGtvvallllllgvsletivddYlltnlyleeaveelraqrpgavqteeqylflyeallellrs
0049260 (Phosphotyrosine protein) phosphatases II 21-73 1.9e-06 23.2 In-house 97-143 (152) alignment 
Range on Protein: 21-73
Range on HMM: 97-143/152.0
TFGSGRACTFIGALYAIhqlnngVEPNIFEIMKTIKQQRPGAIESFPQYSGVY
. | ||. |.. |.. .         ...|... ....||||.... |.  .|
saGvgRtgtlvaaylml......lgvsleeavalvrekRpgavpnpgqlrfly
0046846 (Phosphotyrosine protein) phosphatases II 22-79 8.5e-07 24.4 In-house 118-172 (176) alignment 
Range on Protein: 22-79
Range on HMM: 118-172/176.0
FGSGRACTFIGALYAIHqlnnGVEPNIFEIMKTIKQQRP-GAIESFPQYSGVYAIVLDY
 | ||..|.. |.  ..    .   ...|.......||| ||.... ||  .|  .| .
aGigRtgtlvaayllel....ekglsveealalvreqRplgavqtpeQyrflyefelll
subfamily_Sponge-PTP11_pd Subfamily Sponge-PTP11 24-82 4.2e-10 34.0 In-house 227-285 (290) alignment 
Range on Protein: 24-82
Range on HMM: 227-285/290.0
SGRACTFIGALYAIHQLNNGVEPNIFEIMKTIKQQRPGAIESFPQYSGVYAIVLDYISR
 ||. .|. |  .| . .     ..|...|. ..|.|| ...  || |.. ||| |...
vgrsavfcaaattinkcktegvidvfqvlksqRiqkpgsvqtvqqyqgifqivltylds
subfamily_Sponge-PTP9_pd Subfamily Sponge-PTP9 35-81 9.8e-06 19.5 In-house 248-294 (301) alignment 
Range on Protein: 35-81
Range on HMM: 248-294/301.0
YAIHQLNNGVEPNIFEIMKTIKQQRPGAIESFPQYSGVYAIVLDYIS
 .. |       ..|.. |......|||.    ||. .| ..  |..
iglEQckaegVVdvfqvtkavrrskpgaVtTLeqytsiydvidmylq