Synonym: CELE_Y113G7C.1, Y113G7C.1
Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
---|---|---|---|---|---|---|---|---|---|
WSN | Domain of unknown function | 173-239 | 1.2e-22 | 69.5 | Pfam-A | 2-68 (69) | alignment | ||
Range on Protein: 173-239
Range on HMM: 2-68/69.0
NPADFLNHITVVAHVSNGITLQAGLMNGSIPIVEVVDELLDLGSAKVADLVSFKEDKITALVSKLKE
.....|......|.| |||.|||||.|||||| .|..|||..||.....|.....||. . . ||.|
elqtvleklsiiaRvtngIyLqaglingsipiddviaELLnigssslsqllkidvdklkeklnklse
|
|||||||||
Borrelia_P83 | Borrelia P83/100 protein | 975-1151 | 4.1e-06 | 11.6 | Pfam-A | 194-338 (489) | alignment | ||
Range on Protein: 975-1151
Range on HMM: 194-338/489.0
VNKRKEPVDFptlavviplvamllagvaiggflfrqhkiheKDREEEKKRKTQDfQDQQDADIERAEADEQRRKMNVERAKKDEERAKKDKRDAEERRKK
|..|.. || |.|| ... | .. . ....| . .||....|... ... | .| . .. |... .
velrrdivDl...............................keresqedakraq.vlkeeldkkqkdadkakkkadtaednadkqrkevreklqeaknlp
DEERAKKDKEDAKKAKEDQEKIDKLAAEVKEREEKSLARHEKEEEDEKRRLKEEEDVKQLNKERAMEREEQLIGDMK
.. . .. ||| | |.| . .|.| |.|...|. . .... || |. |.|| . .. | . |.. .|..
epadvsskkedkkvaeekkreiekaqkeikkkdeeakkakdakaedlkkeskaeekeaedkeleakkereevaeDlq
|
|||||||||
subfamily_Cele-PTP-19_pd | Subfamily Cele-PTP-19 | 1148-1444 | 2.3e-170 | 560.1 | In-house | 4-300 (301) | alignment | ||
Range on Protein: 1148-1444
Range on HMM: 4-300/301.0
GDMKVWIISQDHQDADKTARFYNATMDQVYVTTLDKDNMTKSLGYLHKDKHRYDGVPCKPLTAVEVMDNGKRVPIHANWIPTHGHPHRFIATQGPLDNTC
....||||.|..|.||||.|||.|...|.|||.|||..|.|..||.||||||. ||||| |||||...|||||||||||||.|||||||||||||.||.
kkiekwiiskdfkdddktakfynttienvnvttidkdhitesyaylpkdkhryptvPckPstavevivdGkrvPihanwiptsGhphrfiatqgPlknts
EDFWAMCVYHNVDKIAMLCLNVEKNVKKCAVYFASDPPSKLDIGRFQITTQSRQLILRDNVIERKLLVKDTTGKFEPKTVTHYQHVKWPDRDTPKTHVDT
||||||.|...|.||.||. .|||...||. |.......|||||||.|......|||......|.| |.|.||||...||||||...|.||..||.|...
edfwamlvqydvekivmlgqkvekleekceeylpvkisekldigrfkikiknkelilnkkiskrtlevedstgkfatrtvthyqysewtdrgvPkshael
FELMELVKKSENPIVVHCSAGIGRTTAFIGTEYLAREVENDPKIELTEALKHLREHRWKGVQMRSQLYWMTLGAVYRLIREYNFNMRMHTDLMKDFD
|.|||||||||.||||||||||||..|||||||||||||.||.|||||||||||||||.|||..|||||||||.|||||.||.|.|.........||
fdlmelvkksekPivvhcsaGiGrsvafigteylareveadptieltealkhlrehrwngvqtnsqlywmtlGtvyrlikeygfdmkiyeeqlamfd
|
|||||||||
0045450 | (Phosphotyrosine protein) phosphatases II | 1148-1417 | 4.3e-64 | 212.5 | In-house | 9-296 (307) | alignment | ||
Range on Protein: 1148-1417
Range on HMM: 9-296/307.0
GDMKVWIISQDHQDADKTARFYNATMDQVYVTTLDKDNMTKSLGYLHKDKHRYDGVPCKPLTAVEVMDNGKRVP----IHANWI--------PTHGHPHR
|..... . . .| .... . . . ||. . .... .| . .|||.|| ... . | | ... ..... |.|... ... ....
idalkllllvllllldfltgllkefekllsvtvfllgeysiallpenkdknrykdilpydhtRVklssldgsledsdYiNAsyvrvpllllldgydlkrk
FIATQGPLDNTCEDFWAMCVYHNVDKIAMLCLNVEKNVKKCAVYFASDpPSKLDIGRFQITTQSRQLilRDNVIERKLLVKDTTGKFEPKTVTHYQHVKW
||||||||..|.|||| |. ..| | ||. ||.. .||| |. .. ..| .|.|..|. | . |... |.| |.|. |..|. ||||... .|
fIatqgPlpetvedFwrmlweqgvtvivmltelvelgrekcaqywPde.geeltygnftvtllseeh..ldgytvrtlevtdldgtgesrtvthfhytgw
PDRDTPKTHVDTFELMELVKK------SENPIVVHCSAGIGRTTAFIGTEYLAREVENDPK---IELTEALKHLREHRWKGVQMRSQLYWM
|| ..|.. ......|.|.| ...|..||||||.||| .||. .. | .|.... . | ||.|.|||.|...|| .|...
pdhgvppsfeelldfieevrkaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrfl
|
|||||||||
subfamily_Cele-PTP-14_pd | Subfamily Cele-PTP-14 | 1149-1414 | 5.1e-21 | 69.5 | In-house | 13-279 (310) | alignment | ||
Range on Protein: 1149-1414
Range on HMM: 13-279/310.0
DMKVWIISQDHQDADKTARFYNaTMDQVYVTTLDKDNMTKslgYLHKdkHRYDGVPCKPLTAVEVMDNGKR--VPIHANWIPTHGHPHRFIATQGPLDNT
.. .||. .. . .. | .| ..| . ..| |.|| || | |. . | . . | ||||.. | || .||||. |
alenfiiateklgieglvkqyr.kldakqdssltyeaykk...ymhk..nrysdvvcldtsrvklkidksryedyihanyvktnylrstficsqgplqht
CEDFWAMCVYHNVDKIAMLCLNVEKNVKKCAVYFASDPPSKlDIGRFQITTQ---SRQL---ILRDNVIERKLLVKDTTGKFEPKTVTHYQHVKWPDRDT
||| | . | .|| .|. || |. | .. | ..| | .. | . .. | . ... |. . .||||
iidfwrmifqeraesilllckvgeegrpkcvgywpslgvte.tygcirvtnlsesseefeicnlavtfvpdnvpvdeqpanlkelrvslikwpnwpdrgv
PKTHVDTFELMELVKKSENPIVVHCSAGIGRTTAFIGTEYLAREVENDPKIELTEALKHLREHRWKGVQMRSQL
| .. | | . | |||||||..|. . . .. ... |... | .|. .| . .| |
pdekchtvpqrllaqvrhgpcvvhcsagkdrlyvvvalklkidkldrglkvdaeevktellksraiciqtelqy
|
|||||||||
subfamily_PTPRB_pd | Subfamily PTPRB | 1162-1417 | 4.8e-41 | 135.7 | In-house | 21-277 (293) | alignment | ||
Range on Protein: 1162-1417
Range on HMM: 21-277/293.0
ADKTARFYNaTMDQVYVTTLDKdNMTKSLGYLHKDKHRYDGVPCKPLTAVEV---MDNGKRVPIHANWIPTHGHPHRFIATQGPLDNTCEDFWAMCVYHN
|| .|| . .... |. ..... ..| || . . |.. |. . | ||.|| . |. |||||||| .| .||| |. ..
adsdlrfse.eyeelkavgkdq.avkaaelavnraknrytnilpydhsrvkLaalkdesgsDYinanyipgynsprefiatqGPlpetvddfWrmvwekk
VDKIAMLCLNVEKNVKKCAVYFASDPPSKlDIGRFQITTQSRQLilRDNVIERKLLVKDttgKFEPKTVTHYQHVKWPDRDTPKTHVDTFELMELVKK--
. | || ||| .|| |. .| . | ..| .. . .. . |.|... . | ..|..|... ||| . |.. .... |..
ssiivmltqlvekgkvkCeeYWPadeepv.lyGdikvtlvaeee..ledwvirelkiek...ekeerkvrqyhftsWpdhgvPektktlldfvrtvreai
----SENPIVVHCSAGIGRTTAFIGTEYLAREVENDPKIELTEALKHLREHRWKGVQMRSQLYWM
|..|||||||||.||| .|| . | ...|.. .... . .|||.| || .| ..
ektaskrPivvhCsaGvGRtGtfialdrllqaieeedyvdifgivaelReeRnllvqtekqYifi
|
|||||||||
subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 1164-1414 | 3.4e-38 | 126.5 | In-house | 23-272 (305) | alignment | ||
Range on Protein: 1164-1414
Range on HMM: 23-272/305.0
KTARFYNATMDQVYVTTLDKDNMTKSLGYLHkDKHRYDgVPCKPLTAVEVMDngKRVPIHANWIPTHGHPHRFIATQGPLDNTCEDFWAMCVYHNVDKIA
. |.. ... . ..|... |. |. .. .| ||. | .| .. | |... .. . ...|..||||.|| .||| . | | .|
gleaqykslyeeeesidvgkkeankaknrlk.eitlld.ddriiltekesld..dsdyinasyvdgykrkkkyivaqgPlkntvadfWrliveekvstiv
MLCLNVEKNVKKCAVYFASDPPSKLDIGRFQITTQSRQLIlrDNVIERKLLVKDTTGKFEPKTVTHYQHVKWPDRDTPKTHVDTFELMELVKKS----EN
||. || . .|| |.. | ..|.|... .|.. . . ||||| . .. | .||..|| .||| |.. .|.. |.|. ..
mltklveggkdkCrqYWpesktekkefgefsvelksekta..sdyieRklkisiededkesrtvlqyqltdWPdhGvpqfatsllslikrvqkdqkkdkg
-PIVVHCSAGIGRTTAFIGTEYLAREVENDPKIELTEALKHLREHRWKGVQMRSQL
|..||||||.||| .|| . .... ... | ||.||..| | || |
vpllVhCsagvgRtGvfiavdialerlkkEevvdvfevlkqlRskrmkmvqtldqY
|
|||||||||
0039614 | (Phosphotyrosine protein) phosphatases II | 1166-1417 | 2.2e-59 | 196.7 | In-house | 32-281 (297) | alignment | ||
Range on Protein: 1166-1417
Range on HMM: 32-281/297.0
ARFYNATMDQVYVTTldkDnMTKSLGYLHKDKHRYDGVPCKPLTAVEVMDNGK----RVPIHANWIPTHGH-PHRFIATQGPLDNTCEDFWAMCVYHNVD
.... .. . .. | .. .| . .|||.|| ... . . | . .... |.|...... . ...||||||||..|.|||| |. ..|
tllllefeellslkp...d.ysiallpenkdknrykdilpydhsrvklkpedgvdldsdYinAsyvdgydlltrkfIatqgPlpetvedFwrmvweqgvt
KIAMLCLNVEKNVkKCAVYFASDPPsklDIGRFQITTQSRQLilRDNVIERKLLVKDtTGkfEPKTVTHYQHVKWPDRDTPKTHVDTFELMELVKK----
| ||. ||... ||| |. .. |.|..|. . . .|... |.| |.. .| |..||||.|...||| ..| .. . .|..|||..
vivmLtklvelgr.kcaqywpeegg...tygdftvtllkveh..ldgytvrtlevtn.ng..esrtvthfqytgwpdhgvppslellleflelvrealae
--SENPIVVHCSAGIGRTTAFIGTEYLAREVENDPKIELTEALKHLREHRWKGVQMRSQLYWM
...|..||||||.||| .||. .. . .| .. . ||.|.|||.|...||. ||...
lpkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavqtpsqyrfl
|
|||||||||
subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 1169-1416 | 3.4e-33 | 109.9 | In-house | 25-269 (287) | alignment | ||
Range on Protein: 1169-1416
Range on HMM: 25-269/287.0
YNATMDQVyvtTLDKDNMTKSLGYLHKDKHRYDGVPCKPLTAVEVMdNGKRVPIHANWIPTHGHPHRFIATQGPLDNTCEDFWAMCVYHNVDKIAMLCLN
....|| | ..|..| .. ||| |. . . | . . . | | .| .. . ..||....|. || .|| . .|| | ||| .
qftvleqv...tqredevthniasqnkdknRltqilvpdnyrvllk.gehpdyinavfidgykekkafiiaesPmfntarnfWkliddrnvtaivmlcqe
VEKNVKKCAVYFASDPPskLDIGRFQITTQSRQliLRDNVIERKLLVKDTTGKFEPKTVTHYQHVKWPDRD---TPKTHVDTFELME--LVKKSENPIVV
|.. ..| |.... . .| ..|. ... ...||||| || .. . ....|. || .|... .|.| . .| | |... .|||
kendeevcyqyWpeeks..vvlGeyniellnee..vnagyierklevknknkagdkqqvkqyqitnWdstgkvtepqtillvieemyktqrkrgntsivv
HCSAGIGRTTAFIGTEYLAREVENDPKIELTEALKHLREHRWKGVQMRSQLYW
|||...||.. |. . ...... |.. . ||. | . . || .|
hCsdtvGrsamfcaaattinkckteGviDvfqvlksqriqkpgsvqtveqykf
|
|||||||||
subfamily_Sponge-PTP5_pd | Subfamily Sponge-PTP5 | 1171-1417 | 2.9e-29 | 96.9 | In-house | 13-257 (283) | alignment | ||
Range on Protein: 1171-1417
Range on HMM: 13-257/283.0
ATMDQVYVTTLDKDNMTkslGYLHKDKHRYDGVPCKPLTAVEVMDNgKRVPIHANWIP---THGHPHRFIATQGPLDNTCEDFWAMCVYHNVDKIAMLCL
..... | || | . .| | |.. . . ||. . | | | .|| . . ...|..|.|||.| ||| | ... | ||
evlkrlsvpdldadias...adenkrknrnqeivpadqwrvelkse.srdyinavfipvsksykqdkkyiiaqsPldrtvvdfWkmvfdekitaivmltk
NVEKNVKKCAVYFASDppSKLDIGRFQITTQSRqlILRDNVIERKLLVKDTTGKFEPKTVTHYQHVKWpDRDTPKTHVDTF----ELMELVK-KSENPIV
| . .||. |. .. | | | .| . . | ..||.. . . ..||| . | ... .... .. | . . . |||
lqedlrikCsqyWPkr..GsedyGeftvtlrke..ttsnsfiikelllrvnssakstlllahyqvidW.leygeqaiinslvkfnkvislqteskkgPiv
VHCSAGIGRTTAFIGTEYLAREVENDPKIELTEALKHLREHRWKGVQMRSQlYWM
||||.|||||..||. .. . ... . .| .||.| || . | | .
vhCstgiGrtavfiaasasvkdaltesvvdvfavvkimreqrmmavqtldq.ykl
|
|||||||||
0049772 | (Phosphotyrosine protein) phosphatases II | 1171-1409 | 4.3e-26 | 87.8 | In-house | 23-263 (314) | alignment | ||
Range on Protein: 1171-1409
Range on HMM: 23-263/314.0
ATMDQVYVTTLDKDNMTKSLGYLHKDKHRYDGVPCKPlTAVEVmD---NGKRVPIHANWIPTHghpHRFIATQGPLDNTCEDF----------WAMCV--
...... ..| . .... .|..|| || ... . . | . . . |.|... .. .||||||||..|..|| | | .
lvlnrrslsvlpeltilvadlflnrdknryldilpad.nrvil.pglpvsgsdyinasyvdgf...lkfIatqgpleitvvdfreepvlyyngwrmvlrg
YHNVDKIAM---------------------LCLNVEKNvkkcavyfasDPPSKLDIGRFQittqsrqlilrdnvierkllvkDTT--GKFEPKTVTHYQH
.|| | | |. ... . |. |. .. . . ... .... .| .
dlnvrdivmsrdevladelsrLdaAlgKtpllildgng..........neptaadlellk......................eelydpelferlgikylr
VKWPDRDTPkTHVDTFELMELVKK--SENPIVVHCSAGIGRTTAFIGTEYLAREVendpKIELTEALKHLREHRW----KGVQ
. .|| ..| . | |..|.... ..|..|||.||.|||. |. . || . .. | |||...|. | .|
ipvpDgsap.lledfdeflefieeadkggpvlvHCkaGkgRtgtfvvaaylmkll....gvsleealedvrlkRpinpnpgfi
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 1174-1344 | 1.2e-11 | 38.8 | In-house | 22-180 (319) | alignment | ||
Range on Protein: 1174-1344
Range on HMM: 22-180/319.0
DQVYVTTLDKDNMTKSlgylhkdkhrydgVPCKP--LTAVEVMDNGKRVPIHANWIPTHG-HPHRFIATQGPLDNTCEDFWAMCVYHNVDKIAMLCLNVE
|.| ||. ||... .. || . . .. |. | ..|... . | .||.| .|... ||| . . | |. |
devPvtskdksrvinv.............vPlPetrvvlqrigdddkdeyldasyvrGyddapnsyiaaqvsledsssdfwrtvweqqsrvivqltdlse
KNVKKCAVYFASD--PPSKLDIGRFQITTQSRQLilRDNVIERKLLVKDTTGKfEPKTVTHYQHvKWPDRDTPKTH
. .|.|| |. . ... | ...| . |. .|. . ||.| .. | . .||| . ||.. . | .
lGikvcaeylPtketldntslyGdilvtlkgrev..kdryaistlllkrvdke.esrelthywy.kwleaevPaee
|
|||||||||
0040438 | (Phosphotyrosine protein) phosphatases II | 1178-1447 | 6.2e-66 | 218.2 | In-house | 27-293 (317) | alignment | ||
Range on Protein: 1178-1447
Range on HMM: 27-293/317.0
VTTLDKDNMTKSLGYLHKDKHRYDGVPCKPLTAVEVMDNGKRVP---IHANWIPTHGHPHRFIATQGPLDNTCEDFWAMCVYHNVDKIAMLCLNVEKNVK
. .|..|... .. . .|||.|| ... . . | . . |.. . |.|...... ....||||||||.||.|||| |. ..| | ||. .|....
llslkldtysvaelpenkdknrypdilpydhsRVkLsplggdldsdYInAsyvdgpnlkrkfIatqgPlpntvedFwrmvweqgvtvivmLteleelgre
KCAVYFASdpPSKLDIGRFQITTQSRQLilRDNVIERKLLVKDTtGKFEPKTVTHYQHVKWPDRDTPKTHVDTFELMELVKKS----ENPIVVHCSAGIG
||| |. . ..| .|.|..|..| . .... |.| |.|. |. |. ||||... ||| ..|... . ....|.|... ..|..||||||.|
kcaqYwpl..getltygdftvtllseee..lagitlrtlevedl.gdsesrtvthfhytgWpdhgvppspdllldfleavrealedpggpvlVHCsaGvg
RTTAFIGTEYLAREVENDPKIELTEALKHLREHRWKGVQMRSQLYWMtlgavYRLIREYNFNMRMHTDLMKDFDRVV
|| .||. ... . .| .. ..||.|.|||.|...||. .|.... |....|| . . ..... . ...
RtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrfl.....ydalleylkrkltlepaselklkll
|
|||||||||
0043336 | (Phosphotyrosine protein) phosphatases II | 1180-1416 | 1.4e-58 | 193.9 | In-house | 31-268 (278) | alignment | ||
Range on Protein: 1180-1416
Range on HMM: 31-268/278.0
TLDKDNMTKSLGYLHKDKHRYDGVPCKPLTAVEVMDNGKRVP---IHANWIPTHGHPHRFIATQGPLDNTCEDFWAMCVYHNVDKIAMLCLNVEKNVKKC
. ..|... .| . .|||.|| ... . . | . . |.. . |.|...... .|..||||||||..|.|||| |. ..| | ||. ||....||
sfkldtysiallpenkdknrykdilpydhsrvklsllggdldsdYinAsyvdgynvprkfiatqgPlpetvedFwrmvwelgvttivmLtelvelgrvkc
AVYFAsdpPSKLDIGRFQITTQSRQLilRDNVIERKLLVKDtTGKFEPKTVTHYQHVKWPDRDTPKTHVDTFELMELVKK----SENPIVVHCSAGIGRT
| |. . | .|.|..|... . |... |.| |.. .|. |..|||||....||| ..| . . ..... |.. |..|..||||||.|||
aqYwp...ggsltygdftvtllkeeh..lddytvrtlevtn.lgdgesrtvthyhylgwpdhgvpeslsllldflkavrealedsngpvlVHCsaGvgRT
TAFIGTEYLAREVENDPKIELTEALKHLREHRWKGVQMRSQLYW
.||. ..| . .|. .. | ||.|.|||.|.. ||. ||...
GtfialyllleqlekeggvdleeavkelreqRpgavqtpsqyrf
|
|||||||||
subfamily_egg_pd | Subfamily egg | 1180-1446 | 1.1e-18 | 61.9 | In-house | 26-287 (307) | alignment | ||
Range on Protein: 1180-1446
Range on HMM: 26-287/307.0
TLDKDNMTKSLGYLHKDKHRYDGVPCKPLTAVEV-MDNGKRV--PIHANWIPTHGHPHRFIATQGPLDNTCEDFWAMCVYHNVDKIAMLCLNVEKnvKKC
. |. ..|... ...| | |.|| . |.. . .|. . |||| . . || .| || || .||| | .|. | || ..| ..|
svdeislttaasdnnlekarskrvhckdssrvklelrrGqylddfihanrvkGkpllnefilaqaplkntvddfwrmvfqeevqyivmltsrkes..erc
AVYFASDPPSKLDI--GRFQITTQSRQLIlRDNVIE-RKLLVkdTTGKFEPKTVTHYQhvkWPDRDTPKTHvDTFELMELVKKSENPIVVHCSAGIGRTT
|. . | . | ..|.. . | . || . |. | . . |.| . . . . . .... .... .|.||.. |. ...
eyywpkaesdslvtvpGslrienlkvdsk.adplfrvtklkl..vGgddeerflehwq...gdvnnssdvy.splrvlrklrnlskpvvvqdilGvskaa
AFIGTEYLAREVENDP--KIELTEALKHLREHRWKGVQmrSQLYWMTlgaVYRLIRE-YNFNMRMHTDLMKDFDRV
... | .. | | . .| . || .| |. | | .. ||||. . . .| |..|
tlvaieiallsllrGpitkslvlravvflrlrrrlsve..svllylf...vyrlvlfffrdvigsakeldvdyerw
|
|||||||||
subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 1180-1414 | 5.8e-18 | 59.9 | In-house | 19-248 (267) | alignment | ||
Range on Protein: 1180-1414
Range on HMM: 19-248/267.0
TLDKDNMTKSLGYLHKDKHRYDGVPCKPLTAVEVMDNGKRvPIHANWIPTHGHPHRFIATQGPLDNTCEDFWAMCVYHNVDKIAMLCLNVEKNVKKCAvy
. .. ....|.. ....|.| . | | . .. . | | .. .. . ||.||.||.|| ||. . ..| | .| . |...
sdtsstisqsiaeknqernrlddnlpyddtrvilrtkeee.yinasyvegyktknafivtqdplkntitdfltvihdqkvpvivlltkvftdnirlfw..
fasdPPSKLDIGRFQITTQSRQLILRDNVIerKLLVKDTTGKFE-PKTVTHYQHVKWPDRDTPKTHVDT-FELM--ELVKKSENPIVVHCSAGIGRTTAF
|| . ..| | . | .| .... . | | . || | . || | .. | .. . ... ..|.||.||.|.||. .|
....PPkmgqakkyqdltvehslekeendy..qiitlelkfknesahnvtlyyykkwnintnnkpylkplfgilaknqlengnrPlvvacsdGvGrsGtf
IGTEYLAREVENDPKIELTEALKHLREHRWKGVQMRSQL
. . . . .. .. . |...|. | |. . .
lvidsqleraktegvsdifdflrkirsqriglvdtkery
|
|||||||||
0050432 | (Phosphotyrosine protein) phosphatases II | 1181-1418 | 3.9e-62 | 205.7 | In-house | 55-292 (308) | alignment | ||
Range on Protein: 1181-1418
Range on HMM: 55-292/308.0
LDKDNMTKSLGYLHKDKHRYDGVPCKPLTAVEVmdNGKRVPIHANWIPTH--GHPHRFIATQGPLDNTCEDFWAMCVYHNVDKIAMLCLNVEKNVKKCAV
. ... .| .|||.|| ... . | . ... |.|...... ..|..||||||||.||.|||| |. .|| | ||. ||....|||
kplleysvallpenkdkNrykdilpydhsRVkl..degsdYInAsyvdgyssklprkfIatqgPlpntvedFwrmvweqnvrvIvmLtklvengrekcaq
YFASDPP-SKLDIGRFQITTQSRQLilRDNVIERKLLVKDTTGKfEPKTVTHYQHVKWPDRDTPKTHVDTFELMELVKKS--ENPIVVHCSAGIGRTTAF
|. ... . | .|.|..|. | . .|... |.| .... .. | .||||... ||| ..| . ....|||.|| ..|||||||||.||| .|
Ywplelgggsleygkftvtllseev..lddytvrtleltnlgdg.esrtvthfhytnWpdhgvPpspeilldflelvrkslpggpivVHCsaGvGRtGtf
IGTEYLAREVENDPKIELTEALKHLREHRWKGVQMRSQLYWMT
| ..| . .| . .. . ||.|.|||.|. || .|....
ialdllleqlekeggvdvfeavkklReqRpgmvqtpeqylfly
|
|||||||||
subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 1181-1416 | 1.2e-40 | 134.4 | In-house | 33-270 (288) | alignment | ||
Range on Protein: 1181-1416
Range on HMM: 33-270/288.0
LDKDN-MTKSLGYLHKDKHRYDGVPCKPLTAVEVMD---NGKRVPIHANWIPTHGHPHRFIATQGPLDNTCEDFWAMCVYHNVDKIAMLCLNVEKNVKKC
|.|.. |.. ..| || . ..|.. . . . | |..| ... ...||||||| .| .||| . ... |.|| ||.. .||
lektksvtagrlavnakknRyrnilpyDekrvklkkleeeagaDYinasyidgekkkkkyiatqgPladtvndfWelvyenktstivmltelveggktkC
AVYFASDPPSKlDIGRFQITTQSRQLilRDNVIERKLLVKDTTGKFepkTVTHYQHVKWPDRDTPKTHVDTFELMELVKKS--E--NPIVVHCSAGIGRT
|. .. | | ...| .. . .....||||.. ..... ..|.||. ||| . |. . . .||.. || . . .||.||||||.|||
eeYWPdadkpk.nyGsvtvtlveske..ledfvlrklllekkktel...eitqyqylaWpdhgvPeskapllellrqvkvanqadtgpiivhCsaGvGrt
TAFIGTEYLAREVENDPKIELTEALKHLREHRWKGVQMRSQLYW
|| . | .||.. .|........||..| || .| .
gtFialdalidaveeedyiDvagtvaklRkqRallvqtlkqYef
|
|||||||||
0045098 | (Phosphotyrosine protein) phosphatases II | 1182-1418 | 4.2e-55 | 182.4 | In-house | 21-265 (278) | alignment | ||
Range on Protein: 1182-1418
Range on HMM: 21-265/278.0
DKDNMTKSLGYLHKDKHRYDGVPCKPLTAVEvmDngkrvPIHANWIPTHghPHRFIATQGPLDNTCEDFWAMCVYHNVDKIAMLCLNVEKNVKKCAVYFA
. . .| .| ..||.|| ... . . | | |.|..|... |..||||||||..|..||| |. ... | ||. ||....||| |.
ipseitpalylgnldknRykdilpydhsrVk..d.....YINAsyidgy..pkkfIatqgPlpstvadfwrmlwelgitvivmltelvelgrekcaqywp
SdpPSKLDIGRFQITTQSRQLIlrDNVIERKLLVKDT---TGKFEPKTVTHYQHVKWPDRDTPKTH--VDTFELMELVKK-----------------SEN
. . | .|.|..|..| . . |... |.||| .. .|. .|||.. . ||| ..| .. .||.| ... |..
e..ggsltygdftvtllseevl..ddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllsslllldsgg
PIVVHCSAGIGRTTAFIGTEYLAREVenDPKIELTEALKHLREHRWK-GVQMRSQLYWMT
|..||||||.||| .... .. . . .... | ||.|.||..|. ||. .|....
pvlVHCsaGvgRtGtlvaaylmlell..eggvdlleavkelrsqRpglavqnleqyrfly
|
|||||||||
subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 1182-1434 | 1e-38 | 128.2 | In-house | 36-291 (319) | alignment | ||
Range on Protein: 1182-1434
Range on HMM: 36-291/319.0
DKDNMTKSLGYLHKDKHRYDGVPCKPLTAV---EVMDNGKRVPIHANWIPTHGHPHRFIATQGPLDNTCEDFWAMCVYHNVDKIAMLCLNVEKNVKKCAV
..|..... |.| || . | | |. . . | |..| .. . ..|||||.||.|| |||| | ... . ||. ||| |.
vndtfdsaskeenkkknryqnilaydrtrvvlseldgvegsdyinasfidgyqerekfiatqaPlentiedfWrmvWeeessivvmltklveklkvklkk
YFASDPPSklDIGRFQITTQSRQLilRDNVIERKLLVKDTTGKFEPKTVTHYQHVKWPDRDTPKTHVDTFELMELVKKSE-----NPIVVHCSAGIGRTT
|. . . . ||. .| .... ...| ||| .. ... | ..|.|.|. .||| | |.. .|.. ..|| |||||||||.|||
ywpeenfe..eyGrlivtleeeee..ledyiirklklnkkssevetRevkhfqyteWpdhdvPekatslldllkrirksrektqsgPivvhCsaGvGRtG
AFIGTEYLAREVENDPKIELTEALKHLREHRWKGVQMRSQlYWMTLGAVYRLIREYNFNMR
.|| . |... ... . ..|| | || .| | . |. . .. ...
tfivldamlervkeegvlDvfstvsrlRtqRnimvqrpeq.Ykfiyealleaveagdteie
|
|||||||||
0047943 | (Phosphotyrosine protein) phosphatases II | 1183-1417 | 1.1e-60 | 200.8 | In-house | 27-264 (273) | alignment | ||
Range on Protein: 1183-1417
Range on HMM: 27-264/273.0
KDNMTKSLGYLHKDKHRYDGVPCKPLTAVEVmDNGKRVPIHANWIPTHGHPHRFIATQGPLDNTCEDFWAMCVYHNVDKIAMLCLNVEKNVKKCAVYFAS
... .| .|||.|| ... . | . ..|. |.|...... ....||||||||.||.|||| |. .|| | ||. ||.. .||| |. .
lltysvallpenkdknrykdilpydhsrvkl.gdggsdyinAsyvdgynlkrkfiatqgPlpntvedfwrmvweqnvrviVmLtelvelgrekcaqYwpl
DPPS-KLDIGRFQITTQSRQLilRDNVIERKLLVKDTTGKFePKTVTHYQHVKWPDRDTPKTHVDTFELMELVKK------SENPIVVHCSAGIGRTTAF
. . .| |.|..|. | . .|... |.| .... . ..||||... .||| ..| . . .|..|||.| |..|.|||||||.||| .|
eggelsltygkftvtllseet..kddytvrtleltnlgtge.srtvthfhytgwpdhgvppslesllefielvrkalealpsngpvvVHCsaGvgRtgtf
IGTEYLAREVENDPKIELTEALKHLREHRWKGVQMRSQLYWM
| ..| . .| .. . ||.|.||..|. .|| .|....
ialdllldqlekeggvdvleavkllrsqRpgmvqtpeqyrfl
|
|||||||||
0051299 | (Phosphotyrosine protein) phosphatases II | 1184-1417 | 6e-59 | 195.2 | In-house | 39-278 (288) | alignment | ||
Range on Protein: 1184-1417
Range on HMM: 39-278/288.0
DNMTKSLGYLHKDKHRYDGVPCKPLTAVEVMDNGK---RVPIHANWIPTHGHPHRFIATQGPLDNTCEDFWAMCVYHNVDKIAMLCLNVEKNVKKCAVYF
... .| ...|.|| ... . | . . .. |.|..|... ....||||||||.||.|||| |. .|| | ||. ||....||| |.
ltlsaallpenleknRysdilpydhsRVkLsvldgvegsdYinAsyidgynlkrkfIatqgPlpntvedFWrmvweqnvrvIvmltklvelgrekcaqYw
ASdpPSKLDIGRFQITTQSRQLilRDNVIERKLLVKDTT---GKFEPKTVTHYQHVKWPDRDTPKTHVDTFELMELVKKS----ENPIVVHCSAGIGRTT
. ..| .|....|. | . |... |.| |.... |. |..||||... .||| ..| . . .....||.|. ..|.|||||||.|||
pl..ggsltygditvtllseev..lddytvrtlevtnldlldgdgesrtvthfhytnwpdhgvpdspellldflrlvrkalasgggpvvVHCsaGvgRtg
AFIGTEYLAREVENDPKIELTEALKHLREHRWKGVQMRSQLYWM
.|| ..| . .|. .... ||.|.|||.|. ||. .|...
tfialdllleqlekeggvdvleavkrlreqRpgmvqtpeqyrfv
|
|||||||||
0046845 | (Phosphotyrosine protein) phosphatases II | 1184-1419 | 8.2e-59 | 194.6 | In-house | 18-268 (284) | alignment | ||
Range on Protein: 1184-1419
Range on HMM: 18-268/284.0
DNMTKSLGYLHKDKHRYDGVPCKPLTAVEVMDNGKR----VPIHANWIPTH-----GHPHRFIATQGPLDNTCEDFWAMCVYHNVDKIAMLCLNVEKNVK
... .| . ...|.|| ... . | . ... |.|...... ....||||||||.||.|||| |. .|| | ||. ||....
lslsvallpenlsknRykdilpydhsRVklksldgdledsdYinAsyvdgydldltyikkkfIatqgPlpntvedFwrmvweqnvrvIVmltelvengre
KCAVYFASDpPSKLDIGRFQITTQSRQLilRDNVIERKLLVKDTTGKFEPKTVTHYQHVKWPDRDTPKTHVDTFELMELVKKS------ENPIVVHCSAG
||| |. .. ..| .|.|..|. |.. .|... |.| .... . |..||||... .|||...| . | .|...||... ..|||||||||
kcaqYwple.gevltygdftvtllseev..kddytvrtleltnlgytgesrtvthfhytswpdhgvppspedlleflrlvrellenlpgggpivVHCsaG
IGRTTAFIGTEYLAREVENDP---KIELTEALKHLREHRWKGVQMRSQLYWMTL
.||| .|| ..| . .|.. .. . ||.|.|||.|. ||. .|...
vgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvqtleqyrfvye
|
|||||||||
DSPc_SM00195 | 1185-1418 | 9.4e-59 | 194.2 | In-house | 17-255 (263) | alignment | |||
Range on Protein: 1185-1418
Range on HMM: 17-255/263.0
NMTKSLGYLHKDKHRYDGVPCKPLTAVEVMDNG---KRVPIHANWIPTHGHPHRFIATQGPLDNTCEDFWAMCVYHNVDKIAMLCLNVEKNVKKCAVYFA
..|.. |.|.|| ... | |.. .. . |.||.| .. .....|||||||..|.|||| |.. ..| |.||. ..|.. .||. |.
etteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivmlteeeengkekcdrywp
SDPPSKLDIGRFQITTQSRQLILrDNVIERKLLVKDTTGkFEPKTVTHYQHVKWPDRDTPKTHVDTFELMELVKKSEN----PIVVHCSAGIGRTTAFIG
.. .| ..|........ . |..| |.| .. .. |...||.||. .|||...|... ...||.. ||||.. |||||||||.||| .|.
eesggketfgkisvklvevekkk.deiilrtleltkegk.eetrkvtqyqyknWpdhgvpdstksvlellravkkskstssgpivVhCsaGvgRtgtfvt
TEYLAREVENDPKIELTEALKHLREHRWKGVQMRSQLYWMT
.... ...|.. |... | .|.||..| . ||.. |. ..
idiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiy
|
|||||||||
PTPc_SM00194 | 1185-1418 | 9.4e-59 | 194.2 | In-house | 17-255 (263) | alignment | |||
Range on Protein: 1185-1418
Range on HMM: 17-255/263.0
NMTKSLGYLHKDKHRYDGVPCKPLTAVEVMDNG---KRVPIHANWIPTHGHPHRFIATQGPLDNTCEDFWAMCVYHNVDKIAMLCLNVEKNVKKCAVYFA
..|.. |.|.|| ... | |.. .. . |.||.| .. .....|||||||..|.|||| |.. ..| |.||. ..|.. .||. |.
etteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivmlteeeengkekcdrywp
SDPPSKLDIGRFQITTQSRQLILrDNVIERKLLVKDTTGkFEPKTVTHYQHVKWPDRDTPKTHVDTFELMELVKKSEN----PIVVHCSAGIGRTTAFIG
.. .| ..|........ . |..| |.| .. .. |...||.||. .|||...|... ...||.. ||||.. |||||||||.||| .|.
eesggketfgkisvklvevekkk.deiilrtleltkegk.eetrkvtqyqyknWpdhgvpdstksvlellravkkskstssgpivVhCsaGvgRtgtfvt
TEYLAREVENDPKIELTEALKHLREHRWKGVQMRSQLYWMT
.... ...|.. |... | .|.||..| . ||.. |. ..
idiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiy
|
|||||||||
0040439 | (Phosphotyrosine protein) phosphatases II | 1185-1416 | 1.7e-56 | 186.9 | In-house | 2-237 (249) | alignment | ||
Range on Protein: 1185-1416
Range on HMM: 2-237/249.0
NMTKSLGYLHKDKHRYDGVPCKPLTAVEVMDNGKRVP---IHANWIPTHGHPHRFIATQGPLDNTCEDFWAMCVYHNVDKIAMLCLNVEKNVKKCAVYFA
... .| . .|||.|| ... . . | . . ... . |.|..|.. ...|||||||||..|.|||| |. ... | ||. ||.. .||| |.
eysvallpenkdknrypdilpydhsrvklsilpglflsdyinAsyidgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqywp
SdpPSKLDIGRFQITTQSRQLilRDNVIERKLLVKDTtGKFEPKTVTHYQHVKWPDRDTPKTHVDTFELMELVKK------SENPIVVHCSAGIGRTTAF
. . | .|.|..|. | . |... |.| .... .. |. ||.|.|...||| ..|.. |.....|.|.| ...|..||||||.||| .|
l..ggsleygdftvtllsvev..kddytvrtleltnl.ydgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtf
IGTEYLAREVENDPKIELTEALKHLREHRWKGVQMRSQLYW
|. .. . .| .. | ||.|.||..|...||. .|...
iaaylmleqlekelgvdleeavkllrsqRpgavqnpeqyrf
|
|||||||||
0036941 | (Phosphotyrosine protein) phosphatases II | 1186-1436 | 2.6e-66 | 219.3 | In-house | 31-287 (297) | alignment | ||
Range on Protein: 1186-1436
Range on HMM: 31-287/297.0
MTKSLGYLHKDKHRYDGVPCKPLTAVEVmDNGKRVPIHANWIPTHGHPHRFIATQGPLDNTCEDFWAMCVYHNVDKIAMLCLNVEKNVKKCAVYFASDPP
.. .| ...|.|| ... . | | . |... |.|...........||||||||.||.|||| |. .|| | ||. ||.. .||| |. .. .
lsvallpenleknRykdilpydhtRVkl.ddegsdYinAsyvdgydlkrkfIatqgPlpntvedFWrmvweqnvtvIvmltelvelgrekcaqywpleeg
SKLDIGRFQITTQSRQLILRDNVIERKLLVKDTtGKFEPKTVTHYQHVKWPDRDTPKTHVDTFELMELVKK------SENPIVVHCSAGIGRTTAFIGTE
. | |.|..|..| . .| |... |.| |.|| |. |..||||... .||| ..| .. . ....|||.| |..|..||||||.||. .||. .
esltygdftvtllsvevvllddytlrtlevtdt.gngesrtvthfhytgwpdhgvpespaslldfielvrkvlkllpsggpvlVHCsaGvgRsgtfiaad
YLAREVE---NDPKIELTEALKHLREHRWKGVQMRSQLYWMtLGAVYRLIREYNFNMRMH
.. . .| ... . ||.|.|||.|. ||. .|.... |.. |.. ... ...
lmlqqledklkeggvdileavkklReqRpgavqtleqyrfl.yeallellkkkltkepll
|
|||||||||
subfamily_Cele-PTP-6_pd | Subfamily Cele-PTP-6 | 1186-1417 | 3.2e-40 | 133.0 | In-house | 33-269 (307) | alignment | ||
Range on Protein: 1186-1417
Range on HMM: 33-269/307.0
MTKSLGYLHKDKHRYDGVPCKPLTAVEVMDNGKRV-PIHANWIPTHGHPHRFIATQGPLDNTCEDFWAMCVYHNVDKIAMLCLNVEKNVKKCAVYFASDP
.| || ||. |.|. . . | .| ||||.. . .|..||..||||.|| .||||.. ..|. . ||| .| || |. .
vtveafsantdknryqdvkcqdkgrivvkfdglasdyihanylgiaikpkkficaqgplentqysfwamaiqekvesvimlckvielakikceqywplee
PSKLDIGRFQITTQSR-----QLILRDNVIERKLLVKDTTGKfePKTVTHYQHVKWPDRDTPKTHVDTFELMELVKKSENPIVVHCSAGIGRTTAFIGTE
|| | | .| ...|. | | ..| .|..|.| .|||| .|.. . . .|.| |. .||.|||||||.||. . ..
gqklvfgeapntisvanlgakklapdedlinvttlkvdwaqk..srtiqhlqwenwpdrgvpqinltainlleavrydtnpvvvhcsaGvGrsGtivais
YLARE-VENDPKIELTEALKHLREHRWKGVQMRSQLYWM
.. .. .. . .. ||..| .| | ..
lvqdkmiaGinckdmkklveelrsqrhyaiqteaqylyl
|
|||||||||
subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 1186-1418 | 2e-36 | 120.6 | In-house | 38-272 (318) | alignment | ||
Range on Protein: 1186-1418
Range on HMM: 38-272/318.0
MTKSLGYLHKDKHRYDGVPCKPLTAVEVMDNGKRV---PIHANWIPTHGHPHRFIATQGPLDNTCEDFWAMCVYHNVDKIAMLCLNVEKNVKKCAVYFAS
.||| | | || . | |.. . . . | ||.|. . . . .||.|.|| .|.|||| | | | || .|. .|.. |. |
slkslepvnkaknryanilaydhtrvkLqmlegeegsDyinanyidGyrrkkayiaaqaPlpetieDfWrmvWeqnsavivmltqeeergkakvhryWPs
DPPSKldIGRFQITTQSRQliLRDNVIERKLLVKDtTGKFEPKTVTHYQHVKWPDRDTPKTHVDTFELMELVKKSE-----NPIVVHCSAGIGRTTAFIG
. . . .|. ... ... .. . |.. |. |.. | ..| |.. .|||...|. .. .|. |.| . .|||||||||.||| ||
kgsrs..ygklvvelkeev..elsdyvlrefkvtr.teeeesrqvrqyhytsWpdegvpesgaslldlvrqvskaqqksgagpivvhCsaGvGrtGvfia
TEYLAREVENDPKIELTEALKHLREHRWKGVQMRSQlYWMT
. | . .... ... . |.|||.| || ..| | .
vdillerikaealvDvfqtvkqlreqrnlmvqtedq.yefi
|
|||||||||
0037934 | (Phosphotyrosine protein) phosphatases II | 1187-1416 | 2.7e-50 | 166.5 | In-house | 3-233 (243) | alignment | ||
Range on Protein: 1187-1416
Range on HMM: 3-233/243.0
TKSLGYLHKDKHRYDGVPCKPLTAVEVmdNGkRVPIHANWIPTHGhphRFIATQGPLDNTCED----FWAMCVYHNVDKIAMLCLNVEKNVKKCAVYFAs
. .| . ...|.|| .... . . | . .| |.||.|. . |.|||||||..|.|| || |. .... | ||. ||....||| |.
siallpenlsknrysdilpydhsrvkl..eg.sdyinanliyvtp...rliatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqywp.
dpPSKlDIGRFQITTQSRQLilRDNVIERKLLVKDTTGKFEPKTVTHYQHVKWPDRDTPKTHVDTFELMELVK------------KSENPIVVHCSAGIG
.. .|.|..|. | . |... |.||.. . . ....|.||... ||| ..| .. | .... |. .|..|..||||||.|
..gev.tygdftvtllseeh..lddytvrtlllenldlddltrlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvg
RTTAFIGTEYLAREVendpKIELTEALKHLREHRWK-GVQMRSQLYW
|| ..| .. . . .. | ||.|.|||.|. .|| .||...
RtGtliaaylmllll....gvdleeavkllreqRpgkavqtpsqyrf
|
|||||||||
subfamily_Cele-PTP-16_pd | Subfamily Cele-PTP-16 | 1188-1429 | 8.7e-10 | 32.7 | In-house | 41-278 (303) | alignment | ||
Range on Protein: 1188-1429
Range on HMM: 41-278/303.0
KSLGYLHKDKHRYDGVPCKPLTAVEVMDNGKrvpIHANWIPTHGHpHRFIATQGPLDNTCEDFWAMCVYHNVDKIAMLCLNVEKNVKKCAVYFASDPPSK
| || |. | | . |.. | |||... . . .. | || || |. ||| | . .| . .| . | . . | .
knqfvknmdknrfvdvicldhskvklsdssy...ihasyleldss.kkailtqlplshtaadfwqmiieqkvkcvlllltdseydklggdsvfprnqdfl
LDIGRFQITTQSRQLILRDNVIERKLLVKDTTGkfepKTVTHYQHV-KWPDRDTPKT-----HVDTFELMELVKKS--ENPIVVHCSAGIGRTTAFI--G
|. . ... | | . | | . . |. | .| .|| . | . ..| ...| .| | .| ||. .|
kfeersirvgefkrvelgdgwvlkvlsvsngdy....ksflhvhhykawphnsipsdgspkfvkqiwqlqsvlrkysdstptvymslsgcgragtfalfe
TEYLAREVEnDPKIELTEALKHLREHRWKGVQMRSQLywmtlGAVYRLIREY
| .|. | .. ..| |. .|. | . || ||. || |. |.
tahlslhse.qasldlvkclenvrngrlhavqnlsqf.....svvytllaeh
|
|||||||||
0042113 | (Phosphotyrosine protein) phosphatases II | 1192-1417 | 5e-56 | 185.2 | In-house | 7-235 (245) | alignment | ||
Range on Protein: 1192-1417
Range on HMM: 7-235/245.0
YLHKDKHRYDGVPCKPLTAVEVMDNGKRV---PIHANWIPTHGHPHRFIATQGPLDNTCEDFWAMCVYHNVDKIAMLCLNVEKNVKKCAVYFASdpPSKL
. .|||.|| ... . | | ... | . .|.|...... ....||||||||..|.|||| |. ... | ||. .|.. .||| |. . ..|
penkdknrysdilpydhtrvklspdggdldsdyinasyvdgyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywpl..gesl
DIGRFQITTQSRQLilRDNVIERKLLVKDtTGKFEPKTVTHYQHVKWPDRDTPKTHVDTFELMELVKK-----SENPIVVHCSAGIGRTTAFIGTEYLAR
.|.|..|. | . |... |.| |.. .|..|...|.||... ||| ..| .. . ....|.|.| |..|..||||||.||| .||. ....
tygdftvtllseeh..lddytvrtlevtn.lgddesrevihyhylpwpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylmle
EVENDPKIELTEALKHLREHRWKGVQMRSQLYWM
.| .. | ||.|.||..|.. ||. ||....
qlekelgvsleeavkelrsqRpgavqtpsqyrfl
|
|||||||||
subfamily_PTPN13_pd | Subfamily PTPN13 | 1192-1416 | 1.7e-39 | 130.8 | In-house | 35-260 (273) | alignment | ||
Range on Protein: 1192-1416
Range on HMM: 35-260/273.0
YLHKDKHRYDGVPCKPLTAVEVMDNGKrvPIHANWI--PTHGHPHRFIATQGPLDNTCEDFWAMCVYHNVDKIAMLCLNVEKNVKKCAVYFASDPPSKLD
.||| || | | |.. |.| | |..| | . ...||.|||| .|..||| | ... |||. |..||. || |. . .||
kenkdknryrnvlPydetrvklgdegg..yinaslikvpvgkdeyeyiacqGPlPetvkdfwqmvweqkaeviamvtlekekgkvkchrywPesknkklk
IG-RFQITTQsrQLILRDNVIERKLLVKDTTGKfEPKTVTHYQHVKWPDRDTPKTHVDTFEL---MELVKKSENPIVVHCSAGIGRTTAFIGTEYLAREV
. |.... .. .|. |.| |||. . | . |.| . ||||| ..|.. .. .. . ..... ||||||||||||. ..| . . .
vsnrlevell..kvqkldgfvvralavkdsesg.esrevahlnfvkwPdhgvPssaaellqfvaevrrlqtdagPivvhcsaGiGrsGtlitidvvlgli
ENDPKIELTEALKHLREHRWKGVQMRSQLYW
|.| .....| ...||| | || . | .
erdkefdvkeivrklreqrqgvvqtkdqyif
|
|||||||||
subfamily_Cele-PTP-10_pd | Subfamily Cele-PTP-10 | 1193-1417 | 1.7e-40 | 133.5 | In-house | 54-281 (305) | alignment | ||
Range on Protein: 1193-1417
Range on HMM: 54-281/305.0
LHKDKHRYDGVPCKPLTAVEVMDNGKRVPIHANWIPTHGHP-HRFIATQGPLDNTCEDFWAMCVYHNVDKIAMLCLNVEKNVKKCAVYFASDPPSKLDIG
. . | ||. |||. ..|| . . ||||.. | .|||..|||||.| ..|| | . ..|..| ||| || ||| |. ||..
iaitknryqdvpcqdqsavkldkpspsdyihanyvgcpmipekrficaqgpldqtidefwwmviqnkveqivmlcktvelgklkcaqywpaaqgeklelk
RFQI--TTQSRQLILRDNVIERKLLVKDTTGKfEPKTVTHYQHVKWPDRDTPKTHVDTFELMELVKKSENPIVVHCSAGIGRTTAFIGTEYLA-REVEND
. . . ||. |. || .|. . .| | | .|||| | .. ..||. .. |. ||||||||||||| . . ||. . ||
sgivvenvsgskpmerdaeiqitllnltysgd.qkmsvrhlqwtewpdrgvppckltslellsairgskvpivvhcsagigrtgtivaieyilekiaenk
PKIELTEALKHLREHRWKGVQMRSQLYWM
| . | .| ||..| .| | ..
pcppmpelvkalrdqrafsiqndvqylfi
|
|||||||||
subfamily_Cele-PTP-15_pd | Subfamily Cele-PTP-15 | 1193-1418 | 6.5e-37 | 122.0 | In-house | 34-263 (285) | alignment | ||
Range on Protein: 1193-1418
Range on HMM: 34-263/285.0
LHKDKHRYDGVPCKPLTAVeVMDNGKRVPIHANWIPTHGHP-HRFIATQGPLDNTCEDFWAMCVYHNVDKIAMLCLNVEKNVKKCAVYFASDPPSKLDIG
| || | | | | |. | | |||.|. |. .|.||||| .| ||| | .. . ||| .| |.|||.|. . .|
anpdlnryadvrcieetrv.vlknhdrdyihaswmrmpgkdqstyittqgplpetlsdfwhmiyqekiayvlmlctlfeggvekcalyypeklgevvkfg
RFQIT-TQSRQLILRDNVIERKLLVKDTTGKFEPKTVTHYQHVKWPDRDTPKTHVDTFELMELVKK---SENPIVVHCSAGIGRTTAFIGTEYLAREVEN
...|| |. .. . ... ... || . | | |||. .|. || . ||| |.||.||||||.|||..|.| .| . . .
kyeitlteckeeaiagtilnaltvintedasseplymnhvqvpwwpdqlapedarpmielykwvkkvnpkekpicvhcsagvgrtatfvgidyatirime
DPKIELTEALKHLREHRWKGVQMRSQLYWMT
.|.||. . .. .| |.. || . |. ..
npniemldivremramrfqavqshmqflfly
|
|||||||||
subfamily_PTPN1_pd | Subfamily PTPN1 | 1193-1417 | 5.9e-28 | 92.4 | In-house | 31-263 (290) | alignment | ||
Range on Protein: 1193-1417
Range on HMM: 31-263/290.0
LHKDKHRYDGVPCKPLTAVEvMDNGKRVPIHANWIPTHGHPHRFIATQGPLDNTCEDFWAMCVYHNVDKIAMLCLNVEKNVKKCAVYFASDPP-SKLDIG
... || | . .. ..... | |. . . ...| ||||| ||.. || | .. . || |||. ||| |. .. ..| .
enrnlnryrdvspydhsrik.leradndyinaslveleeakrsyiltqGPlpntvdhfWqmvWeqkskavvmlnkvvekeqikcaqywPqgeeekellle
--RFQITTQSRQliLRDNVIERKLLVKDTTGKfEPKTVTHYQHVKWPDRDTPKTHVDTFELMELVKKS------ENPIVVHCSAGIGRTTAFIGTEYLAR
..... |.. ... . |.| ... . . | ....|. ...||| |.. .... |..| | |.||||||||. .|. . .
dtklkvklisee..rksyytvrllelenlktq.etreilhfhyttwpdfgvpespaaflkflfkvresGslssdvGpavihcsaGiGrsGtfclvdtclv
EVENDPK---IELTEALKHLREHRWKGVQMRSQLYWM
..|. . ... . | .||..| .| || .
liekkddlssvdikkvllelrkyrlGliqtadqlrfs
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 1194-1417 | 5.5e-57 | 188.2 | Pfam-A | 1-229 (235) | alignment | ||
Range on Protein: 1194-1417
Range on HMM: 1-229/235.0
HKDKHRYDGVPCKPLTAVEV-MDNGKRVPIHANWIPTHGHPHRFIATQGPLDNTCEDFWAMCVYHNVDKIAMLCLNVEKNVKKCAVYFASDPPSKLDIGR
.|.|.|| ... | |.. ..|. |.||.. .. ....||||||||..|.||||.|.. ..| |.||. ..||. .||| |. .. .| |.
nkkknRykdilpydktrvklkgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeesltygd
FQITTQSRQLILRDNVIERKLLVKDTTGKFEPKTVTHYQHVKWPDRDTPKTHVDTFELMELVKKSE----NPIVVHCSAGIGRTTAFIGTEYLAREVEND
......... .... ||| .|..... |...|..... .|||...|.. . ..|.. |.||. .|.|||||||.||| |. ..| ...|..
ikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldilleqleae
PKIELTEALKHLREHRWKGVQMRSQLYWM
.... ...|.||..| . || .|....
eevdvlqivkelRkqRpgmvqsleqYifl
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 1194-1417 | 5.5e-57 | 188.2 | In-house | 1-229 (235) | alignment | ||
Range on Protein: 1194-1417
Range on HMM: 1-229/235.0
HKDKHRYDGVPCKPLTAVEV-MDNGKRVPIHANWIPTHGHPHRFIATQGPLDNTCEDFWAMCVYHNVDKIAMLCLNVEKNVKKCAVYFASDPPSKLDIGR
.|.|.|| ... | |.. ..|. |.||.. .. ....||||||||..|.||||.|.. ..| |.||. ..||. .||| |. .. .| |.
nkkknRykdilpydktrvklkgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeesltygd
FQITTQSRQLILRDNVIERKLLVKDTTGKFEPKTVTHYQHVKWPDRDTPKTHVDTFELMELVKKSE----NPIVVHCSAGIGRTTAFIGTEYLAREVEND
......... .... ||| .|..... |...|..... .|||...|.. . ..|.. |.||. .|.|||||||.||| |. ..| ...|..
ikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldilleqleae
PKIELTEALKHLREHRWKGVQMRSQLYWM
.... ...|.||..| . || .|....
eevdvlqivkelRkqRpgmvqsleqYifl
|
|||||||||
subfamily_Cele-PTP-18_pd | Subfamily Cele-PTP-18 | 1194-1416 | 7.5e-44 | 144.7 | In-house | 48-278 (305) | alignment | ||
Range on Protein: 1194-1416
Range on HMM: 48-278/305.0
HKDKHRYDGVPCKPLTAVEVMDNGKRVPIHANWIPTHGHPHRFIATQGPLDNTCEDFWAMCVYHNVDKIAMLCLNVEKNVKKCAVYFASDPPSKLDIG--
...| || | | | . ||||.. | |.||| || ||..|| ||| ||. ..|..| ||| .|| |||. ||||. .|..
eagknrykdvgcldnnrvklegpwpheyihanyvstptnpkrfictqaplektcadfwymclqdkveaifmlcnllekgakkcleyfaskdkdvlefeek
RFQITT---QSRQLILRDN---VIERKLLVKDTTGKFEpKTVTHYQHVKWPDRDTPKTHVDTFELMELVKKSENPIVVHCSAGIGRTTAFIGTEYLAREV
.|. | .| .|.. .... || . .|. . |||| . |||| | . . .||.| . | ||||||||||||| . . ||. ..
gqkisvkfessvtlkfrkdakakvtetvlviegpgeka.rkvthyhwidwpdrgvpaadlailellekarpskgpivvhcsagigrtgsvvmleyildql
ENDPKIELTEA-LKHLREHRWKGVQMRSQLYW
. .|| |. |...|| | . .| | .
lagqiiedtdkilqkireqrnnsiqtdaqylf
|
|||||||||
subfamily_Cele-PTP-11_pd | Subfamily Cele-PTP-11 | 1194-1438 | 3.9e-30 | 99.6 | In-house | 43-288 (312) | alignment | ||
Range on Protein: 1194-1438
Range on HMM: 43-288/312.0
HKDKHRYDGVPCKPLTAVEVMdNGKRVPIHANWIPTHGHPHRFIATQGPLDNTCEDFWAMCVYHNVDKIAMLCLNVEKNVKKCAVYFaSDPPSKLDIGRF
|| || . | . . ||||.. .| ||..|||||.||| || ... | .|| || .||| | || . .|.
fkdlnrypniqcwdrgrftla.gdenfyihanfvkictkperfvctqgplentcthfwqlalslgstsiillcgfvedgsekcakyi.sdivgfvdledh
QITTQSRQLI-----LRDNVIERKLLVK-DTTGKfEPKtVTHYQHVKWPDRDTPKTHVDTFELMELVKKSENPIVVHCSAGIGRTTAFIGTEYLAREVEN
.. |.. | .|.. | | | .||. | | . ||| ||| | . .. |. ||| .|.. |||||.||| ... | . .
rvyteycteieiggkskdkithrvlkvvvkatgq.esk.lnhyqwaswpdhgmpdscdtalrllsavkkdkkpviahcsagvgrtgtlaliesmiaalrh
DPKIELTEALKHLREHRWKGVQMRSQlYWMTLGAVYRLIREYNFNMRMHTD
| .. ... || | . |.. | | ..| .| .. . | . .
prkqnvkdsfvllrkdrarsvrvfpq.yvyalrcvleflyskglykrneqe
|
|||||||||
subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 1195-1417 | 1.3e-40 | 134.3 | In-house | 42-268 (281) | alignment | ||
Range on Protein: 1195-1417
Range on HMM: 42-268/281.0
KDKHRYDGVPCKPLTAVEVMDNG---KRVPIHANWIPTHGHPHRFIATQGPLDNTCEDFWAMCVYHNVDKIAMLCLNVEKNVKKCAVYFAsDPPSKLDIG
. |.|| . | |.| .| . | ||..|. ....||||||. .....|| | . ..|..|.|. ..|.. || |. |. |.| .|
vlknrYsnivaYDatrvkvtpneenkntDYinanfvpgykgekeyiatqgPvPaslvafWqmvweqkvsaivmvtreieagklkChrYWP.ddnselkyg
RFQITTQSRQLilRDNVIERKLLVKDTTGkfEPKTVTHYQHVKWPDRDTPKTHVDTFELMELV-----KKSENPIVVHCSAGIGRTTAFIGTEYLAREVE
......... . . ||||. .. ..| |...|.. ....||| |.| . .| . | ||.. |.|.|||||.||| ..|. . |...||
dvtvkstaeee..katyierkfkleresg..etreveqlaytaWPdhGvPattkellefrkevlkltekktkaplvihCsaGvGrtGtyialDrlvkave
ND-PKIELTEALKHLREHRWKGVQMRSQLYWM
.. ....... ...||..| || | ..
aeleeldvkavvaelrkernlmvqtvvqyefv
|
|||||||||
subfamily_PTPN3_pd | Subfamily PTPN3 | 1195-1417 | 5.3e-39 | 128.8 | In-house | 42-267 (280) | alignment | ||
Range on Protein: 1195-1417
Range on HMM: 42-267/280.0
KDKHRYDGVPCKPLTAVEVMDNGKrVPIHANW----IPTHGHPHRFIATQGPLDNTCEDFWAMCVYHNVDKIAMLCLNVEKNVKKCAVYFASdPPSKLDI
.| || . | |.. .. . | ||. ||..| |.|||||||..|..||| | ... | || .||. .|| |. . . .|.
lsknryrdilpydatrvklkeset.dyinanyvnmeipstglvnryiatqGPlaktatdfWqmvweqksslivmlttlverGrvkChqyWPe.tedeley
GRFQITTQSRqlILRDNVIERKLLVKDTTGKfEPKTVTHYQHVKWPDRDTPKTHVDTFELMELVKKS----ENPIVVHCSAGIGRTTAFIGTEYLAREVE
|.|... ... . ... |.|..||.. | | ..... |.. ||| . |. . | .|..| |.| |.|.||||||||||| .| | .|
gefsvkceke..detksyvlrelvlkdketk.eerkilqlqylaWpdhgvPddsadflefvervrklrsgkeePvvvhCsaGigrtGvlilletalalie
NDPKIELTEALKHLREHRWKGVQMRSQLYWM
. .. . ....|. | || || ..
aaepvypldivrtmrdqramlvqtasqykfv
|
|||||||||
0041856 | (Phosphotyrosine protein) phosphatases II | 1195-1421 | 4.7e-38 | 126.0 | In-house | 2-167 (182) | alignment | ||
Range on Protein: 1195-1421
Range on HMM: 2-167/182.0
KDKHRYDGVPCKPLTAvevmdngKRVPIHANWIPTHGHPHRFIATQGPLDNTCEDFWAMCVYHNVDKIAMLClnveknvkkCAVYFAsdppskldigrfq
.||.|| ... . . |.||.. .. |||||||||..|..||. | ... | .|. . |..
ldknrysdilpydhsr.......dldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlt.........eelywp.............
ittqsrqlilrdnvierkllvkdttgKFEPKTVTHYQHVKWPDRDTPKtHVDTFELMELVKKSENPIVVHCSAGIGRTTAFIGTEYLAREvendpKIELT
.........|... ||| ..| ......| |.....|..||||||.||| .... .. . .. |.
..........................ellerlgiqylylpwpDhgvpd.ldelldfieevleeggpvlVHCsaGvgRtgtlvaaylmkkl.....gvsle
EALKHLREHRWKGVQMRSQLYWMTLGA
||.|..|..|...|.. .|... | .
eavklvrsrRpgmvitpnqyfflqlal
|
|||||||||
subfamily_PTPN5_RR_pd | Subfamily PTPN5_RR | 1195-1415 | 2.3e-36 | 120.3 | In-house | 29-258 (274) | alignment | ||
Range on Protein: 1195-1415
Range on HMM: 29-258/274.0
KDKHRYDGVPCKPLTAVEVMDNGK----RVPIHANWIPTH-GHPHRFIATQGPLDNTCEDFWAMCVYHNVDKIAMLCLNVEKNVKKCAVYFASDPPSKLD
. | || . . . | . . | ||.| .. . ..|||||| || .||| | ...|..| || |.| .|||||| . ...
qtknryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntvadfWrmiyqeevqvivmltklkeaneqkCavyfPdaedyeis
IGRFQITTQSRQLILRDNVIERKLLVKDTTGkfePKTVTHYQHVKWPDRDTPKTHVDTFELMELVKKSE-------NPIVVHCSAGIGRTTAFIGTEYLA
.. . .. . |.. |||..| .. ...|.|| . .|||...|. ..|.. |..|. |.||||||||||| .||...
erygdveikvekiverndysvrklvlkyler...ersvkhywytdWPdhksPddantlldlvleveesreeenaklapvvvhCsaGiGrtGcfiaisiav
REVENDPKIELTEALKHLREHRWKGVQMRSQLY
|..... .... . .|| .| || ..|
rqlreeivvdvlkivcnlrldrGGmvqtseqye
|
|||||||||
subfamily_PTPN9_pd | Subfamily PTPN9 | 1195-1417 | 6.4e-34 | 112.3 | In-house | 43-282 (297) | alignment | ||
Range on Protein: 1195-1417
Range on HMM: 43-282/297.0
KDKHRYDGVPCKPLTAVEVMD---NGKRVPIHANWIPTHGHPHRFIATQGPLDNTCEDFWAMCVYHNVDKIAMLCLNVEKNVKKCAVYFASDPPSKLDIG
| || | | | | . . . |.||.. . ... ||||||||..|..||| | ..| | | ||. ||. |. .. | . |
leknrytdvlcydetrvvlakvdedeasdyinanfvdGykqkkafiatqGplkktvsdfWrmvWeqevlvivmttrvvergrlkcgqyWpleeessaefg
RFQITTQSRQliLRDNVIERKLLVKDTTgKFEPKTVTHYQHVKWPDRDTPKTHVDTFELMELVKK-----------------SENPIVVHCSAGIGRTTA
..... . . ... .|.| .|... . | ..|||.| . ||| .|.. . ....| |.. |. ||||||||||||| .
dlsvsnveve..eeedykvrvleiknvk.teesrkvthfqflsWPdyGvPssaaslldvlekvrekqalavkelgdewkghpsgPPivvhcsaGiGrtGt
FIGTEYLAREVENDPKIELTEALKHLREHRWKGVQMRSQLYWM
|| .. ..|. .....|..|.||. | .|. | ..
fitldiclsrleevgtvdvvetvkllrtqrafsiqtpeqyefc
|
|||||||||
subfamily_Cele-PTP-13_pd | Subfamily Cele-PTP-13 | 1195-1387 | 3.9e-24 | 79.8 | In-house | 38-229 (281) | alignment | ||
Range on Protein: 1195-1387
Range on HMM: 38-229/281.0
KDKHRYDGVPCKPLTAVEV---MDNGKR-VPIHANWIPTHGHPHRFIATQGPLDNTCEDFWAMCVYHNVDKIAMLCLNVEKNVKKCAVYFASDPPSKLDI
. | || .|| .. |.. | | . ||||.| . . .| |||| .| ||| | | | ||| .| | .||| || . |..
nkknrylnipcldisrvqlkvkmpnknstdyihanyirspflkrgyiltqgpkketradfwrmiwqenttaivmlcqfletnrekcaeyfprnahcclqf
GRFQITTQSRQlILRDNVIERKLLVKDTtgkfEPKTVTHYQHVKWPDRDTPKTHVDTFELMELVKKSENPIVVHCSAGIGRTTAFIGTEYLAREVEN
.. .. . . . | | | . | . .||. .||| . |.. .... .. | |.|||||.||. ... | . . .
dklsvsyedst.vnkslvttrlnlsyeg....etrlithwlwkewpdwqvpessevmlkilrkirarstppvihcsagvgrsgtlmaveialqsihs
|
|||||||||
subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 1196-1419 | 4.4e-40 | 132.2 | In-house | 58-276 (290) | alignment | ||
Range on Protein: 1196-1419
Range on HMM: 58-276/290.0
DKHRYDGVPCKPLTAVEVMDNGKRVPIHANWIptHGHPHRFIATQGPLDNTCEDFWAMCVYHNVDKIAMLCLNVEKNVKKCAVYFASDPPSKLDIGRFQI
| || |.| | | . | .. .|||.. .| || |||.| .| |.| | . ..| | ||| .|. ||. |. | .| . .
kknrykdvvcndktrvilkdGydGdyvhanyv..kGlkamfiltqGalkdtvidiwrmvlqekvaaivmlceliedGkakceqyypekeGevltfGeitv
TTQSRQlILRDNVIERKLLVKDTTGKFePKTVTHYQHVKWPDRDTPKTHVDTFELMELVKKSENPIVVHCSAGIGRTTAFIGTEYLAREVENDPKIELTE
. . .|.| . | |.| . . |.. . |||. ... . . .. ..| |.||||||||||| .|. | .. . . ...| .
lcseed.dkdaniikktlsvrdkdsGk.ehklkhlkikswpdksvalstlallrtlrilrkasGpvvvhcsaGiGrtGtfvaievglqilldGkeldlld
ALKHLREHRWKGVQMRSQlYWMTL
. ||. | . ||. | | . .
lvralrnsrlnsvqvdiq.ylalv
|
|||||||||
subfamily_Cele-PTP-8_pd | Subfamily Cele-PTP-8 | 1197-1434 | 2.1e-35 | 117.2 | In-house | 46-281 (288) | alignment | ||
Range on Protein: 1197-1434
Range on HMM: 46-281/288.0
KHRYDGVPCKPLTAVEVMDNGKrVPIHANWIPTHGHPHRFIATQGPLDNTCEDFWAMCVYHNVDKIAMLCLNVEKNVKKCAVYFASDPPSKLDIGRFQIT
. ||. .|. .| | . |. . |.|| .... ...|.| .| ||. | | .| | . .|. | ||| .|| .| |.|| | | |||.
rdryenlprcditrvklsddpd.fyiaanvvssakykrrlicaqaPlngtieelWkmllesdveyivmlcellekGkeksaeyfPsklGekarigrlctv
TQSRQlILRDNVIERKLLVKDTTGKfEPKTVTHYQHVKWPDRDTPKTHVDTFELMELVKKSENPIVVHCSAGIGRTTAFIGTEYLAREVENDPKIELTEA
.. .. | ... || .|. |.. | . .|.| |. .. . |.| .|. ..|||||.|||.|||...| . .. . | . . .
vkkkr.adidklvkvsllriskege.ekvivkilhlleWdddgvPenylsplrllevlkslqkPivvhssaGvGrtgtlililialeslrlddflgirsl
LKHLREHRWKGVQMRSQ-LYWMTLGAVYRLIREYNFNMR
|..|||.| | .| | || . . |.. |. .
laklreerfkaiqtemqylyvhrcvleelllkkykvlre
|
|||||||||
subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 1198-1417 | 6.6e-37 | 121.9 | In-house | 24-256 (270) | alignment | ||
Range on Protein: 1198-1417
Range on HMM: 24-256/270.0
HRYDGVPCKPLTAVEVM---DNGKRVPIHANWIP-THGHPHRFIATQGPLDNTCEDFWAMCVYHNVDKIAMLCLNVEKNVKKCAVYFASDPPSKLDIGRF
|| .. .| | | . .. . | ||... .|.....||..|||..| ..|| | . ..| |.|. .||. |||..|....| .|...
nRyadiLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpaepkekvkledg
QITTQSRQLILRDNVIERKLLVKdTTGKFepKTVTHYQHVKWPDRDTPKTHV---DTFELMELVKKS---------ENPIVVHCSAGIGRTTAFIGTEYL
.|.. . . .. | ..| .. ..|. . ..|.....|||. |... .| .|...... ..|..||||||.||| .| ...
kikvlalseekeegyiltrlrle.ekgee..rrlvHfwyntWpdhgvpreedsslstdqllkmlravrrsekeldkaePllvHcsaGvgRtGtlialDia
AREVENDPKIELTEALKHLREHRWKGVQMRSQLYWM
| .|.. |..... ...||..| . || | ..
vrlLeetkkvdvlaiieelRkdRmalvqhpeqyefl
|
|||||||||
subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 1198-1417 | 1.5e-25 | 84.6 | In-house | 42-269 (287) | alignment | ||
Range on Protein: 1198-1417
Range on HMM: 42-269/287.0
HRYDGVPCKPLTAVEVMDNGKR--VPIHANWIPTHGHPHRFIATQGPLDNTCEDFWAMCVYHNVDKIAMLCLNVEKNVKKCAVYFASDpPSKLDIGRFQI
|| | | | . .|. | ||..... . ..|||.|||. | ||| . . ... .... .||. .|| |. . .| . .
nryadvlPiddtrvllsaegelGsdyinanyvasytddeafiaaqgPiaatvrdfwravletrsasvitmtreveearlkcykywPer.evPmrvGGysv
TTQSRQLILRDnVIERKLLVKDTTGKfEPKTVTHYQHVKWPDRDTPKTHVD-------TFELMELVKKSE--NPIVVHCSAGIGRTTAFIGTEYLAREVE
. ... . | | . | .. | . | .. ..|||. . | | . .|| .... |.|||...||||. .. | | . |
vlldydikePe.ygvralrlidletr.earvvkqldllswPdkvlaPtavglirfvldvkqhielardasevGPlvvhddvGiGrsGillatlvlvsrle
NDPKIELTEALKHLREHRWKGVQMRSQLYWM
. ... . .. .|||.| || || .
dlGrvdvaavvirlreyraalvqavvqlrll
|
|||||||||
subfamily_Cele-PTP-1_pd | Subfamily Cele-PTP-1 | 1203-1434 | 2e-28 | 94.3 | In-house | 27-268 (290) | alignment | ||
Range on Protein: 1203-1434
Range on HMM: 27-268/290.0
VPCKPLTAVEVMDNGKRVP---IHANWIpTHGHPHRFIATQGPLDNT-------CEDFWAMCVYHNVDKIAMLCLNVEKNVK----KCAVYFASDPPSKL
|| | | . ||| |||| . | . |.|.|| |. .. |.|| | .|... ||| . ||. . || |. .|
vpLveatrvvLkgygkrfnddyiHAnrv.tcpnglrliltqsPqekitekrnStiekfwwmakqEkvkqvVmlcefeeksantslfaCakYvpesvgeel
DIGRFQITTqsRQLILRDNVIERKLLVKdtTGKFEPKTVTHYQHVKWPDRDTPKTHVDTFELMELVKKSENPIVVHCSAGIGRTTAFIGTEYLAREVE-N
.. ... . . |.|..|.|.|| .. |. ||||.. . | .. ..... .|.. ||.|. |..||| || | |. . .
kfkgltvkC..kskekeddvetRelvvk..fddeeeftvtHsllkgWnklnvqedtktllsliqkvkasktpvivHcvdGiSrsAalaaiilgyQkiaet
DPKIELTEALKHLREHRWKGVQMRSQLYWMTLGAVYRLIREYNFNMR
...|...|| ||..| . .. .| .. |.| ..|.... ..
sgsvkledvlkalrkqralaitsalelafvdagivllaievldqfae
|
|||||||||
subfamily_Sponge-PTP9_pd | Subfamily Sponge-PTP9 | 1207-1379 | 3e-19 | 63.8 | In-house | 58-247 (301) | alignment | ||
Range on Protein: 1207-1379
Range on HMM: 58-247/301.0
PLTAVEVMDNGKRVPIHANWIPTHGHPHRFIATQGPLDNTCEDFWAMCVYHNVDKIAMLCLNVEKNVKKCAVYFASDPPSKLDIGRFQITTQSRQ----L
|. . .| .| | |..| . ..|||.|||...| ||| . . . . .| |.. |. .|| |. . .. . | |..| .. |
ilkpkpnldlcqreyinasyidgysekkkfiaaqgpmkktlvdfWrliwqekpvsivmvtnlkegtkskceqywpnseaeseefgpftvtlvneqvyPdf
ILR-----------DNVIERKLLVKDTTgkfEPKTVTHYQHVKWPDRDT---PKTHVDTFE--LMELVKKSENPIVVHCSAGIGRTTAFIGTE
..| .. ||||. || . ....|. .| ..||. |.| . . .. | . |.|||||....|. .. .
virqlnvkiqdgsnngyierkfkvksdk...sswdvlqlqvtdWpqdGvvreprtvLqviddvihrqqkigggpvvVHCSdtVsrsGvYcsvs
|
|||||||||
subfamily_PTPN6_pd | Subfamily PTPN6 | 1208-1429 | 1.8e-31 | 104.2 | In-house | 68-296 (306) | alignment | ||
Range on Protein: 1208-1429
Range on HMM: 68-296/306.0
LTAVEVMDNGKRV--PIHANWIP--THGHPHRFIATQGPLDNTCEDFWAMCVYHNVDKIAMLCLNVEKNVKKCAVYFASDPPSKLdIGRFQITTQSRQli
| | . ... | || | ..|. ...||||| |..| .||| | . | | |. .||.. .||| |. . .. |. ..|. | .
htrvilkepsvpgsdyinanyikkevkgsdksyiatqgclettvsdFWrmvwqensrvivmttkevErgkekCarYWPdeeekee.yGkisvtnvsek..
LRDNVIERKLLVKDTTGKFEPKTVTHYQHVKWPDRDTPKTHVDTFELMELVKKS--------ENPIVVHCSAGIGRTTAFIGTEYLAREVE---NDPKIE
.. | |.|.|. .. | | ..| .|.. .||| ..|| ...| |.. . ||||||||||||| .|| .. | . .| .| .|.
sladYilRelsvskkkkkkeerevfqyhfksWPdhgvpkdpgavLdfledvnrkqeeleeaeagpivvhCsaGiGRtGtfiviDillkliekkgldadid
LTEALKHLREHRWKGVQMRSQlYWMtlgaVYRLIREY
. .. | .||.| ||. .| | . ||. |..|
iqklvksvreqrsglvqteqq.ykf....vykaikky
|
|||||||||
subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 1211-1444 | 8e-30 | 98.7 | In-house | 63-297 (315) | alignment | ||
Range on Protein: 1211-1444
Range on HMM: 63-297/315.0
VEVMDN-GKRVPIHANWIPTHGHPHRFIATQGPLDNTCEDFWAMCVYHNVDKIAMLCLNVEKNVKKCAVYFASDPPSKLDIGRFQITTQSRQLilRDNVI
.||.|. .. | | |.. . . .||.||||. . .||| | . ..| |.|. | . ||. |. . | ..... | . . .
leviddsPdsdyinasyiksvdddkayiasqgPlkasvddfwrmvlqekvttivmvtkkqegdkikcrqywPdrkadsvefGsikvellslea..dtdgv
ERKLLVKDTTgkfEPKTVTHYQHVKWPDRDTPKTHVDTFELMELVKKS----ENPIVVHCSAGIGRTTAFIGTEYLAREVENDPKIELTEALKHLREHRW
||| .... | .||| .| .|||. ..| ..|. || . | ...||||||.||| .| . .... ... . .| ||..|
arklvtrkse...esrtvtqfqftewPdkGvdkqtssllklikevkadngkkefsllvhcsaGvGrtGvvisidevvaqikrtrsvdvfnfvknlrakrp
KGVQMRSQlYWMTLGAVYRLI--REYNFNMRMHTDLMKDFD
. || . . | . .|| . |. . || ..|.
ylvqteee.yafiydavledllwrntlilvihftdhlqdlh
|
|||||||||
subfamily_Urchin-PTP-4_pd | Subfamily Urchin-PTP-4 | 1211-1424 | 4.8e-19 | 63.0 | In-house | 64-234 (392) | alignment | ||
Range on Protein: 1211-1424
Range on HMM: 64-234/392.0
VEVMD-NGKRVPIHANWIPTHGHPHRFIATQGPLDNTCEDFWAMCVYHNVDKIAMLCLNVEKNvkkcavyfasdppskldigrfqittqsrqlilrdnvi
.||.| .. . | .||. . .||.||| . .||| | .|| |||. | .
leviddipdsdylnasyipsfdnekayiasqgpnaaslddfwrmvfqenvttiamvtklkegd.....................................
erkllvkdtTGKfEPKTVTHYQHVKWPDRDTPKTHVDTFELMELVKKS----ENPIVVHCSAGIGRTTAFIGTEYLAREVENDPKIELTEALKHLREHRW
|. . .||. .. ..|||.| || ..... || |...|||||.||| | . . .. ... . . .|..|
.........kgd.dartvaqfhftewPdkdvpkhtssllkfikevkadfGqythpliihcsagvgrtgvvisidsvvahakktrmvdvfnfvtnirrkrp
KGVQMRSQlYWMTLGAVYR
|| . | | . |||
ymvqtkeq.yafiygavle
|
|||||||||
subfamily_PTPRK_pd | Subfamily PTPRK | 1212-1415 | 2.3e-29 | 97.2 | In-house | 63-267 (314) | alignment | ||
Range on Protein: 1212-1415
Range on HMM: 63-267/314.0
EVMDNG-KRVPIHANWIPTHGHPHRFIATQGPLDNTCEDFWAMCVYHNVDKIAMLCLNVEKNVKKCAVYFASDPPSkldIGRFQITTQSRQLilRDNVIE
..|. . | |..| .. .|. ||.|||||..| .||| . .| | || ||. || |. | | .... . .| ...
itidgdpssdyinaalidsykrpaafivtqgPlqetvkdfWrlvydencasivmltelvevgrvkClkyWPedtev...ygdikvelvetel..laelvv
RKLLVKD-TTGKFEPKTVTHYQHVKWPDRDTPKTHVDTFELMELVKKS----ENPIVVHCSAGIGRTTAFIGTEYLAREVENDPKIELTEALKHLREHRW
| . |. . |. | ..| ..|...||| |.|. ..|. |||| . .|||||||| ||| .|| . . .|.. ... .| | ||...
rifrveklargqeeirevrqfqflgWpdhdvPvsatgllklvrrvkksqeeeaGrivvhCsaGaGrtGtfiaidivldmieregvvdvfnavktlrsrkv
KGVQMRSQLY
|. |
nmveteeqyk
|
|||||||||
subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 1212-1423 | 3.6e-29 | 96.2 | In-house | 63-273 (515) | alignment | ||
Range on Protein: 1212-1423
Range on HMM: 63-273/515.0
EVM-DNGKRVPIHANWIPTHGHPHRFIATQGPLDNTCEDFWAMCVYHNVDKIAMLCLNVEKNVKKCAVYFASDPPSKLDIGRFQITTQSRQLilRDNVIE
||. || . . | ||. . .||.|||.. . .||| . . .|| |||. | . ||. |. | . | ... . | . . |
evindnPhsdyfnasyipsfdndkayiasqgPnkasvddfWrlvlqenvttiamvtklkegdkikcgkyWPdkpgdsvkfGsikvelvslea..ctggik
RKLLVKDTTGkfePKTVTHYQHVKWPDRDTPKTHVDTFELMELVKKSEN----PIVVHCSAGIGRTTAFIGTEYLAREVENDPKIELTEALKHLREHRWK
||| | .||| .. .|||. .|| . |. || ... |...|||||.||| .| . .... ... . .. .|..| .
rkltvlkgdd...srtvtqfhfteWPdkGvpkhtssllklikevkadhgqythpliihcsaGvGrtGvvisidsvvahakttrmvdvfnfvtnirqkrpy
GVQMRSQlYWMTLGAVY
|| . | | . |||
lvqtqeq.yafiygavl
|
|||||||||
0044763 | (Phosphotyrosine protein) phosphatases II | 1212-1418 | 1.4e-24 | 82.1 | In-house | 11-164 (178) | alignment | ||
Range on Protein: 1212-1418
Range on HMM: 11-164/178.0
EVMDNGKRVPIHANWIPthghPHRFIATQGPldntcEDFWAMCVYHNVDKIAMLCLNVEKNVKKCAVYFASDPPskldigrfqittqsrqlilrdnvier
.... .|.|..| |. ......| .|.... .... | .|. ..| . || |. ..
nleglersdyinaseil....pglylgslpp.....addlellkelgithivnlteelelgflkcdpywpeeag..........................
kllvkdttgkfepktvTHYQHVKWPDRDTPKTHVDTFELMELVK----KSENPIVVHCSAGIGRTTAFIGTEYLAREvendpKIELTEALKHLREHRWkG
.|.|. .|| ..| ..|..|... ....|..||||||.||..... .. . .. | ||....||.|. .
................iqylhipipDhgvpdllehflefvefieealdekggpvlVHCsaGvgRsgtlvaaylmkkl.....glsleeaielvrerRp.i
VQMRSQLYWMT
|. ..||...
vpnpgqlrqLy
|
|||||||||
subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 1214-1414 | 1.8e-24 | 81.5 | In-house | 71-277 (325) | alignment | ||
Range on Protein: 1214-1414
Range on HMM: 71-277/325.0
MDNGKRVPIHANWIPTHGHPHRFIATQGPLDNTCEDFWAMCVYHNVDKIaMLCLNVEKNVKKCAVYFASDPPSKLDIGRFQITTQSRQLIlRDNViERKL
|... | |... .. . |.|.| || .| .|.| . . . . .. .... ..||||. . | ... .. . | | | |.|
kddpssdyinasylrddkkkdvflaaqaPltatindlWrlvldWrcsvv.vvlneldlgkdrcavywpkemgksktfGglevklrtieei.sdyv.hrvl
LVKDTTgKFEPKTVTHYQHVKWPDRDTPK---THVDTFELMELV-------KKSENPIVVHCSAGIGRTTAFIGTEYLAREVENDPKIELTEALKHLREH
||.. | | ..| .|. |.| ..| | . .|.. | |. ||.||||||.||| .|| .. .| .. .... . .|.||..
dvkqvk.kGetrsvkqfqlqswddmGvqkrpatlisilqlvkavservtantkastpilvhcsaGvGrtGvfislysalakvieesrvdifgfvkklrkd
RWKGVQMRSQL
| . |. |
rpsmvetvdqy
|
|||||||||
subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 1218-1416 | 1.1e-32 | 108.5 | In-house | 83-281 (298) | alignment | ||
Range on Protein: 1218-1416
Range on HMM: 83-281/298.0
KRVPIHANWIPTHGHPHRFIATQGPLDNTCEDFWAMCVYHNVDKIAMLCLNVEKNVKKCAVYFASDPPSKldIGRFQITTQSRQLilRDNVIERKLLVKD
. | | .. .. . . |||||.|| .| |||| | . ... | || .|.. |. |. .. . |..... .|.. ..| ||| |..
esdYiNAsflhaykgrnafiatqaPltetvedFWrmvteedigtiVmltnleeldktkyhkywPdegket..ygeitvsllskee..fadlivrklkvsk
TTGKfEPKTVTHYQHVKWPDRDTPKTHVDTFELMELVKKS-----ENPIVVHCSAGIGRTTAFIGTEYLAREVENDPKIELTEALKHLREHRWKGVQMRS
.. . . ..| . ....|||...|... ..|.. |..| ..|..|.||||.||. .|| . . |... .... ...| ||..| . || ..
kkee.kerevrqlhftsWpdkgvpenatsvldllrkvrasqqqagnkpvivqCsaGvgRsGtfiaidsvlervkkeqvvDvfqvvkvlRkkrpgavqtee
QLYW
| .
qYvf
|
|||||||||
0046846 | (Phosphotyrosine protein) phosphatases II | 1218-1416 | 1.2e-29 | 98.8 | In-house | 11-164 (176) | alignment | ||
Range on Protein: 1218-1416
Range on HMM: 11-164/176.0
KRVPIHANWIPTHghphRFIATQGPLDNTCEDFWAMCVYHNVDKIAMLCLNVEKNVKKCAVYFASDPPSKLdigrfqittqsrqlilrdnvierkllvkd
. |.||.| .. |.||||||| .|..||..| .... . .|. ||.. ||. |. ..
dldyinanlilgs....rpiatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpeleklgi.............................
ttgkfepktvtHYQHVKWPDRDTPKThVDTFELMELVKKSE---NPIVVHCSAGIGRTTAFIGTEYLARevenDPKIELTEALKHLREHRW-KGVQMRSQ
.|.|. ||| ..| . .||.|.... .|..|||||||||| ... | . . . . |||...||.|. . || ..|
...........qylhlpwpDhgvpdl.elllellefirealkeggpvlVHCsaGigRtgtlvaayllel....ekglsveealalvreqRplgavqtpeQ
LYW
...
yrf
|
|||||||||
subfamily_Sponge-PTP6_pd | Subfamily Sponge-PTP6 | 1218-1417 | 1.8e-21 | 71.1 | In-house | 71-271 (439) | alignment | ||
Range on Protein: 1218-1417
Range on HMM: 71-271/439.0
KRV----PIHANWIPTHGHPHRFIATQGPLDNTCEDFWAMCVYHNVDKIAMLClNVEKNVKkcavYFASDPPSKldIGRFQITtQSRQLILRDNVIER-K
| | ||.| . .. .|||||| ..|..||| . . ... .| ||. |. . | |. || | . |.. | . || |
pgvphshyinanyikGyyddklyiatqgpkkettddfwrlviekktvtivmlt.nlvesyk....ywpsdaevc..ygdiavr.vdrnielpnyvirgfk
LLVKDTTGKFEpKTVTHYQHVKWPDRDTPKTHVDTFELMELV-----KKSENPIVVHCSAGIGRTTAFIGTEYLAREVENDPKIELTEALKHLREHRWKG
.. . |.. | .|| ..... |||.. | ... . |. |.|||||||.||| . | . .. . |... .| ||..| .
vfnerdtteke.rtvlqfhyiawpdknvpaqashvldflrainsandkeeygpvvvhcsagvGrtGtiialdialeqlklenkvdikgivkvlrkqrkqm
VQMRSQLYWM
|| | ..
vqalcqyvfi
|
|||||||||
subfamily_PTPN12_pd | Subfamily PTPN12 | 1220-1427 | 4.9e-41 | 135.5 | In-house | 69-278 (290) | alignment | ||
Range on Protein: 1220-1427
Range on HMM: 69-278/290.0
VPIHANWIPTHGHPHRFIATQGPLDNTCEDFWAMCVYHNVDKIAMLCLNVEKNVKKCAVYFASDPPSKLDIGRFQITTQSRQLILRDnVIERKLLVKDTt
| ||.| ....||.|||| .| .||| | ..|| . |.| .|| . |||. |... ..| .| |..|... . . | . | | |.
dYinanfikgvegkleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkkCerYWpeegeeelefgefevtleeekavddd.flirtLkveaq.
gkFEPKTVTHYQHVKWPDRDTPKTHVDTFELMELVKK----SENPIVVHCSAGIGRTTAFIGTEYLAREVEN---DPKIELTEALKHLREHRWKGVQMRS
| ..|. ... .|||...|... . .||.|||.. ...|.|||||||.||| . | .| . ... ...... . . .||..| || .
..kesrkvyqfhYtaWPDhgvPssaksllelielvrelqesedaPlvvhCsaGvGrtGtiiaidyvrellkaekipeeldvfdlvlelrkqraalvqtke
QlYWMTLGAVYRLIR
| | . || |..
q.yelvykavaelvq
|
|||||||||
subfamily_ptpA1_pd | Subfamily ptpA1 | 1220-1379 | 6.6e-17 | 56.3 | In-house | 76-250 (418) | alignment | ||
Range on Protein: 1220-1379
Range on HMM: 76-250/418.0
VPIHANWIPThGHPHRFIATQGPLDNTCEDFWAMCVYHNVDKIAMLCLNVEKNVKKCAVYFASD----PPSKLDIGRFQITTQSRQLILRDNVIERKLLV
| ||.| .|..||.||||| || ||| | . | || . |. || |. . | | . | | .|. . ||...
dyinanyidg.aypkqfictqgplpntiadfwrmvwenrcriivmlsresencrikcdrywpeqiggeqfsiygngnevfgtysvelveviqdpereiit
KDTTGKFEPKT--VTHYQHVKWPDRDTPKtHVDTF-ELMELV--------KKS--ENPIVVHCSAGIGRTTAFIGTE
.. || .| .|.||. |||.. | | . | .|. . | . ||.||||||.||| .| .
rnirltfegetrditqyqyegwpdhnipd.htqpfrqllhsitnrqnqiipssdrnvpiivhcsagvgrtgtfctav
|
|||||||||
0043147 | (Phosphotyrosine protein) phosphatases II | 1221-1417 | 2.9e-36 | 120.1 | In-house | 7-153 (172) | alignment | ||
Range on Protein: 1221-1417
Range on HMM: 7-153/172.0
PIHANWIPTHGHPHRFIATQGPLDNTCEDFWAMCVYHNVDKIAMLClNVeknvkkcavyfasdppskldigrfqittqsrqlilrdnvierkllvkDTTG
|.|...... .|.|||||||||.||..|||.|. .... | .|. . ...
yinasyldlyyipdrfiatqgplrntladfwrmlkelgithivnlt.el...............................................lydp
KFEPKTVTHYQHVKWPDRDTPkTHVDTFELMELVKK-----SENPIVVHCSAGIGRTTAFIGTEYLArevendPKIELTEALKHLREHRWKGVQMRSQLY
... ... .|... ||| ..| . |..|.... ...|..||||||.||| ... .. .. | ||....||.|...|| ||..
ellerlgiqylylpwpDhgvp.llellleflefidellalspggpvlVHCsaGvgRtgtlvaaylml......lglsleeavalvrekRpgavqnpsqyr
WM
.
fl
|
|||||||||
subfamily_PTPRG_pd | Subfamily PTPRG | 1221-1432 | 8.8e-35 | 114.9 | In-house | 78-293 (563) | alignment | ||
Range on Protein: 1221-1432
Range on HMM: 78-293/563.0
PIHANWIPTHGHPHRFIATQGPLDNTCEDFWAMCVYHNVDKIAMLCLNVEKNVKKCAVYFASDPPSklDIGRFQITTQSRQLILRDNVieRKLLVKDTTG
| ||.| . . . |||||||| .|..||| | .|| | |. ||.. .|| ||. .| . ..| .|.| .... . .| |.| .|..
YinAnyidGyqkskafiatqgplkdtfddFWrmiWeqnvaiivmitnlvergrrkcdvYWPkdese..tygalqvtlieeevlalytv..rtlviknlkl
K-----FEPKTVTHYQHVKWPDRDTPKTHvdTFELMELVKKSE------NPIVVHCSAGIGRTTAFIGTEYLAREVENDPKIELTEALKHLREHRWKGVQ
| . |.|..|. |||| ..|. ...|. .|.| |||||||||.||| .| . | ...... .... . |||.| .| ||
kkkkqcdteklvrqyhytkWPdhgvPehs..lpvLifvkkssaankaeaGPivvHcsaGvgrtGtyivldtllkqiqqenavnvfgflkhiraqRnflvq
MRSQLYWMtLGAVYRLIREYNFN
. | ... |. .|. . .
teEqYifl.hdalleaiaskete
|
|||||||||
subfamily_Ptp69D_pd | Subfamily Ptp69D | 1221-1430 | 1.6e-32 | 107.8 | In-house | 78-286 (307) | alignment | ||
Range on Protein: 1221-1430
Range on HMM: 78-286/307.0
PIHANWIPTHGHPHRFIATQGPLDNTCEDFWAMCVYHNVDKIAMLCLNVEKNVKKCAVYFASDppSKLDIGrfQITTQSRQLILRDNVIERKLLVKDTTG
| |..| .. . ..||| |.|...| .||| | .| | || ||| |||| |.. . . | .| . . .. |.|.| | .
YinasfikgykekkkfiaaqdPveatigDfWRmiaeqevtlivmlsnlteknrkkcakYWpie..devqyg..dilvklvseekhsdyiiReldvskkke
K----FEPKTVTHYQHVKWPDRDTPKTHVDTFELMELV----KKSENPIVVHCSAGIGRTTAFIGTEYLAREVENDPKIELTEALKHLREHRWKGVQMRS
. . . |. |.. |.| |.. ..|.| | |... ||||||||| ||.. |. . | ..... |... | |.||..| ||
esgevedsrkvvqyhytgWkDskvPevargllklieqvrelyklnrsPivvhCsaGvgrsgifvaldsllqqlkaedkvdifetvkdLrsqRnllvqsle
QLYWmtlgaVYRLIREYN
| . .|| . .|.
qYvf.....lyralldys
|
|||||||||
subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 1221-1414 | 4.9e-30 | 99.5 | In-house | 79-268 (315) | alignment | ||
Range on Protein: 1221-1414
Range on HMM: 79-268/315.0
PIHANWIPTHGHPHRFIATQGPLDNTCEDFWAMCVYHNVDKIAMLCLNVEKNVKKCAVYFASDppsKLDIGRFQITTQSRQLilRDNVIERKLlvkDTTG
. ||.|. . ...|.||.|||. .. .||| . ... || || ||.. .|. |. . |. |.. .| .| . ... | | ..
yvnanfidGynkkrryiaaqgpnvasvkdfwrlvfeedigkivmltnlvegekrkaekywpdk...kviyGkitvtrkseev..nteytvrtl...svvf
KFEPKTVTHYQHVKWPDRDTPKTHVDTFELMELVKK----SENPIVVHCSAGIGRTTAFIGTEYLAREVENDPKIELTEALKHLREHRWKGVQMRSQL
. . ..| ... ||| . || . .|. ||. | .||||||||.||| .|| . . ..| . |.. .... .|. | | ||. |
gdnirevvqlhytswpdmgvpkytiplmnlirtvkqhhtnsvgaivvhcsaGvGrtGtfitldavldqaeaenaidvynfitgvrqnrikmvqvaeqy
|
|||||||||
subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 1221-1419 | 2.9e-28 | 94.1 | In-house | 91-285 (319) | alignment | ||
Range on Protein: 1221-1419
Range on HMM: 91-285/319.0
PIHANWIPTHGHPHRFIATQGPLDNTCEDFWAMCVYHNVDKIAMLClnveknVKKCAVYFASDPPSKldIGRFQITTQSRQLIlrDNVIERKLLVKDTTG
| | .. . .. ..||.||||||| .||| | .|. | .| .||. |. . | .||.. .| . .. . |.. . . .
yinasfvtGyqrkdkyiaaqGPldntladfWrmiweyncstivllt......kdkcsqywplkivik..eerfkvkvdsveet..aeyvvrdielsedgk
KFEPKTVTHYQHVKWPDRDTPKTHVDTFELMELV----K--KSENPIVVHCSAGIGRTTAFIGTEYLAREVENDPKIELTEALKHLREHRWKGVQMRSQL
. . . .| . ||| |. .| . |.. | . . ...||||||||.||| ..| . | .... .... . .. ||. | . || |
ekdirkitqfhflGwpdvGvpdypsdlmrlvkkvrhltskenhranivvhcsaGvGrtGvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqy
YWMTL
...
kfiys
|
|||||||||
0051082 | (Phosphotyrosine protein) phosphatases II | 1221-1416 | 3.6e-21 | 70.8 | In-house | 5-144 (151) | alignment | ||
Range on Protein: 1221-1416
Range on HMM: 5-144/151.0
PIHANWIPTHghphrFIATQGPLDntceDFWAMCVYHNVDKIAMLCLNVEKNvkKCAVYFASDPpskldigrfqittqsrqlilrdnvierkllvkdttg
.|..... . .....|||. ||... .... | .|. .| . .|. |. .
yinfsyvtgg.....lyrsggpla....dflellkelgiktivnlrseeerg..ycpeylpelg....................................
kfepKTVTHYQHVKWPDRDTPKTHVDTFELMELVKKS-ENPIVVHCSAGIGRTTAFIGTEYLAREvendpkIELTEALKHLREHRWKGVQMRSQLYW
.|.|.. . ||| ..| . |..||. . ..|..||||||.||| .... ... . | |||...|..|. || | .
....ievlhipildwpdpglplsfdavleflellldkkngpvlvHCsaGkgRTGtlvalylmllg......vsleealeeyrlkrpgvvqpnqqflf
|
|||||||||
subfamily_PTPRD_pd | Subfamily PTPRD | 1222-1435 | 1.3e-44 | 147.8 | In-house | 79-290 (564) | alignment | ||
Range on Protein: 1222-1435
Range on HMM: 79-290/564.0
IHANWIPTHGHPHRFIATQGPLDNTCEDFWAMCVYHNVDKIAMLCLNVEKNVKKCAVYFASDpPsKLDIGRFQITTQSRQLIlrDNVIERKLLVkDTTGK
| |..| .. ... .||||||| .|.|||| |. .|. | || .||. .||. |. .. . .|....| .. . . ... |.. . .. .
INAsfidgyrkrkayIAtqgPlaetiedFWRmvweqnsstiVmltkleEkgkvkchkYWPek.g.tetygeltVtleeeeel..adyeirtfkl.kkkks
FEPKTVTHYQHVKWPDRDTPKTHVDTFELMELVKKS----ENPIVVHCSAGIGRTTAFIGTEYLAREVENDPKIELTEALKHLREHRWKGVQMRSQlYWM
| ..|.......|||.. |.. . .|.. |... . |||||||||.||| .|| ... . .... .... . .|.||..| || ..| |
sesreVrqFhFtsWPdhgvpesatslLdlirkvralnepdagPivVhCSaGVGRTGtfividamlerikeektvDiyqyvkalrkqRnamVqteeQ.YiF
TLGAVYRLIREYNFNMRM
|.. . .| ....
iheailealacgnteves
|
|||||||||
subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 1222-1415 | 1.4e-34 | 114.3 | In-house | 79-273 (290) | alignment | ||
Range on Protein: 1222-1415
Range on HMM: 79-273/290.0
IHANWIPTHGHPHRFIATQGPLDNTCEDFWAMCVYHNVDKIAMLCLNVEKNVKKCAVYFASDpPSKLdIGRFQITTQSRQLILrdNVIERKLLVKDTTGK
|.| .| . . ...||||||. || ||| . . ..| | ||. .|.. .|| |... ..| .| |.|. .. . . . ||||| ||... .
inAcyikgykekkqyiatqgpvsntlvdFWkliwqekvtiivmltniieegkvkCqqYWpds.dtka.ygefsikllneetln..eyierklevknknsa
FEPKTVTHYQHVKWPDRD---TPKTHVDTFELMEL--VKKSENPIVVHCSAGIGRTTAFIGTEYLAREVENDPKIELTEALKHLREHRWKGVQMRSQLY
....||.|| |.. . |.| . ..| |. |. ...||||||...||. |. .. .. . |.. . ||..| . . || |.
gakqsvtqyqitnwdstgkvtnpqtillvieemyktqrkrgntsivvHCSdtvgrsavfcaaattinkcktegvidvfqvlksqRiqkpgsvqtvqqyq
|
|||||||||
0051429 | (Phosphotyrosine protein) phosphatases II | 1222-1422 | 1.4e-33 | 112.1 | In-house | 7-222 (272) | alignment | ||
Range on Protein: 1222-1422
Range on HMM: 7-222/272.0
IHANWIPTHGH---PHRFIATQGPLDNTCEDFWAMcVYHNVDKIAMLCLNVEKNVKKCAVYFA----------SDPPSKLDIGRFQITTQSRQliLRDNV
|.|..... |. |.|.....|||..|..|||.. .... | .|. .|.. || | . .| . .|.. .|..| . | ...
iNardvggygrvvkpgrlyrsggplpltaadfwrl.kelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllsee..llldy
IERKLLVKDTTGKFEPKTVTHYQHVKWPDRDTPKTHvdTFELMELVKKsENPIVVHCSAGIGRTTAFIGTEYLAREVENDPKIE--------LTEALKHL
| |.||.. . . |. .|.|... |||. .|. ||.||. . ..|..||||||..|| .. .|.. |. . .. | ||...|
ilrellltlllsagearevmhlhytdwpdhgvpqea..llellellld.ggpvlvHCsaGkdRTGtvvallllllgvsletivddYlltnlyleeaveel
REHRWKGVQMRSQLYWMTLGAV
|..| . || |... ..
raqrpgavqteeqylflyeall
|
|||||||||
subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 1222-1430 | 2.4e-31 | 104.0 | In-house | 82-284 (297) | alignment | ||
Range on Protein: 1222-1430
Range on HMM: 82-284/297.0
IHANWIPTHGHphRFIATQGPLDNTCEDFWAMCVYHNVDKIAMLClNVEKNVKKCAVYFASDPPSKldIGRFQITTQSRQliLRDNVIERKLLVKDTTGK
. | .... | |.|.|| | ..| .||||| . ..| |.|| . ... |||| |.. . .. | ....| . | |.|.| |. |
vnasfvkgnkh..rlittqmPmkatvadfWamvldeqvstivmln.ddnerdkkcaryWsdkgvtt..fGdvsvvllsvs..ereGfikrelevtkgkak
FEpKTVTHYQHVKWPDRDTPK--THVDTFELMELVKK-----SENPIVVHCSAGIGRTTAFIGTEYLAREVENDPKIELTEALKHLREHRWKGVQMRSQL
. . | ||.|.|||.. .. . .|.. |.| .|.|..|||.||.|||. .. . |.... .... . .|.||..| . || . |
ar.rvvkqyqfveWPdkaverkdsassllklisevrkdfsqnaegPllvhclaGvGrtgvlltidsvvaeakrekevdifglvkklrqerpylvqtkeqy
YWmtlgaVYRLIREYN
. || .. |.
kf.....vyvavleal
|
|||||||||
subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 1222-1416 | 2.8e-31 | 103.6 | In-house | 40-233 (250) | alignment | ||
Range on Protein: 1222-1416
Range on HMM: 40-233/250.0
IHANWIPTHGHPHRFIATQGPLDNTCEDFWAMCVYHNVDKIAMLClNVEKNVKKCAVYFASDPPSKldIGRFQITTQSRQLIlrDNVIERKLLVKDTTgK
| | .. .. . |||||||| .| |||| | . .... | || |.. . |.. |. . . | | ... |.. ... ||| . .. |
inasflhgyderkafiatqgPlqatiedfWrmvleeksgtivmLt.nLkesektyhqywPvekaek..yGdvtvsllskeef..adytkrklklskak.k
FEPKTVTHYQHVKWPDRDTPKTHVDTFELMELVKKSE-----NPIVVHCSAGIGRTTAFIGTEYLAREVENDPKIELTEALKHLREHRWKGVQMRSQLYW
. ..| ....| |||. |.. .||.. |..|. .|..|.||||.||. ||| . . .... .... . .| ||..| . |. ..| .
aderivrqlhfvvWPdkgvPevatavLellkkvqasqqqagnaPvivqCsaGvgrsGafiaidavlerlkkekvvdvfkvikvlrkdrphavesleqyvf
|
|||||||||
0036282 | (Phosphotyrosine protein) phosphatases II | 1222-1416 | 1.1e-30 | 101.9 | In-house | 5-161 (174) | alignment | ||
Range on Protein: 1222-1416
Range on HMM: 5-161/174.0
IHANWIPTHGHPHRFIATQGPLDntcedFWAMCVYHNVDKIAMLCLNVEKNVKKCAVYFASdppskldigrfqittqsrqlilrdnvierkllvkdtTGK
|.|... . . |.||.||||. ||.|. ... . ||. .|.. || |. . . .
inaspldlsyitprliagqgpla.....fwemlkelgittvvmlleekelglykcinywpe....................................lre
FEPKTVTHYQHVKWPDRDTPKTHVdTFELMELVKKS-----ENPIVVHCSAGIGRTTAFIGTEYLAREVEnDPKIELTEALKHLREHRWKGVQMRSQLYW
.. ... .|... |||. .| ... .|....|.. ..|..||||||.||| .... .. | . . .. . .. || .| ..||. ||...
dlerlgiqylylpwpDhgvpdlsi.llefvkfveealsedpggpvlVHCsaGvgRtGtlvaaylmlrgll.eslvdaldlvrelRlqrpgmvqtpsQyrf
|
|||||||||
subfamily_PTPRA_pd | Subfamily PTPRA | 1222-1431 | 3.3e-30 | 100.1 | In-house | 89-296 (330) | alignment | ||
Range on Protein: 1222-1431
Range on HMM: 89-296/330.0
IHANWIPTHGHPHRFIATQGPLDNTCEDFWAMCVYHNVDKIAMLCLNVEKNVKKCAVYFASDppSKLDIGRFQITTQSRQLIlRDNVIeRKLLVK---DT
| | .| . . ..|||.|||...| |||| | .. | || |.. .||| |. .. . | ... . ... | . ||.||. |.
inasfidGykekdkfiaaqGPkeetvedfwrmiweqksativmltelkerkeekcaqywPde..GlvtyGnirvevedetvl.vdytv.rkflvqqlpda
TGKFEPKTVTHYQHVKWPDRDTPKTHVDTFELMELVKKS----ENPIVVHCSAGIGRTTAFIGTEYLAREVENDPKIELTEALKHLREHRWKGVQMRSQL
| . ... |. . ||| | . . ..|.. ||| .|||||||||.||| .|| . . |. . |... |..|.|| | . || |
trekksrlvrqfhftswPdvGvPfepiGmlkllkkvkklnqqsagpivvhcsaGvGrtGtfivldavlervkaerkvdvfefvkrlrlqrpqmvqtdeqy
YWmtlgaVYRLIREYNF
. .|. ..|| .
ef.....iykvlleyyl
|
|||||||||
subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 1222-1420 | 3.7e-28 | 93.8 | In-house | 56-250 (284) | alignment | ||
Range on Protein: 1222-1420
Range on HMM: 56-250/284.0
IHANWIPTHGHPHRFIATQGPLDNTCEDFWAMCVYHNVDKIAMLClnveknVKKCAVYFASDPPSKldIGRFQITTQSRQLilRDNVIERKLLVKDTTGK
| | .| . .....|||||||||| .||| | .|. | .| .||. |. . | .||.. .| . .. . |.. . . . .
inasfitGyqrkdkyiatqGPldntladfWrmiweyncstivllt......kdkcsqywplkivik..eerfkvkvdsvee..seeyvvrdielsedgke
FEPKTVTHYQHVKWPDRDTPKTHVDTFELMELVK------KSENPIVVHCSAGIGRTTAFIGTEYLAREVENDPKIELTEALKHLREHRWKGVQMRSQLY
. .... . ||| |. .| . |.. |. . ...||||||||.||| ..| . | .... .... . .. ||. | . || | .
kdirkirqfhflgwpdvgvpdypsdlmrlvkkvrhltskenhranivvhcsagvgrtgvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqyk
WMTLG
..
fiysa
|
|||||||||
subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 1222-1415 | 4.8e-23 | 76.6 | In-house | 32-229 (237) | alignment | ||
Range on Protein: 1222-1415
Range on HMM: 32-229/237.0
IHANWIPT-HGHPHRFIATQGPLDNTCEDFWAMCVYHNVDKIAMLCLNVEKNVKKCAVYFASDPPSKlDIGRFQITTQSRQlILRDNVIERKLLVKDTTG
| |... | |...||.||||...|.||| | . | || .|.| .|| |. | . | . .. . .. . | . ||.| .|
inatylkgfdgtpkkyiaaqgplesscddfwqmvwqekcsvivmltgliegnelkchkywpstdqpa.aygvltvslkkke.efsdytvrslllskrltl
KfEPKTVTHYQHVKWPDRDTPKTHVDTFELM-ELVKKSEN-----PIVVHCSAGIGRTTAFIGTEYLAREVENDPKIELTEALKHLREHRWKGVQMRSQL
| | . . || |||| |. . . .....|. | ..|||||.||| |. . . |. .. ... . .. . | | .| . |
k.evrlihqyqftswpdrgvpqqtaallrfrkniinrsphvsesgpwiihcsagvgrtgiflvidamlrqakekkvvdiynyvysieedrpyiiqtkdqy
Y
v
|
|||||||||
subfamily_CG7180_pd | Subfamily CG7180 | 1222-1414 | 3.1e-17 | 57.2 | In-house | 73-279 (296) | alignment | ||
Range on Protein: 1222-1414
Range on HMM: 73-279/296.0
IHANWIPTHGHPHRFIATQGPLDNTCEDFWAMCVYHNVDKIAMLCLNVEKNVkKCAVYFASDPpsKLDIGRFQITTQSR----QLILRDNVIERK---LL
| | .. .. ... .| |..| ..| ..|| . .... . .|. . . . .. |. . | . | . . . . .| | . .| |
inavyvdsflkkkeyivteapkketvdefWrlvydeeisavvvLtktfdfak.mypsywpnks..keqygeifveiveekqyanlkirtfkltkkivalt
VKDTTGKFEPKTVTHYQHVKWPD-RDTPKTHVDTFELM---ELVKK-S-----ENPIVVHCSAGIGRTTAFIGTEYLAREVENDPKIELTEALKHLREHR
... | | ..|...| .|. | ||. .|... |.|.||..| | .|. .... . ||.. .... ||.| ||..|
eqekqvkaetRivklfqlteWeledkvPlstnalielrrrvrlwrekvdedpeegPvvvvssdGasRsGvylaidanlelvekeeevdvFeavktlrrsR
WKGVQMRSQL
. |.. .
pqLvenveeY
|
|||||||||
subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 1222-1347 | 2.5e-14 | 47.8 | In-house | 62-188 (297) | alignment | ||
Range on Protein: 1222-1347
Range on HMM: 62-188/297.0
IHANWI--PTHGHPHRFIATQGPLDNTCEDFWAMCVYHNVDKIAMLCLNVEKNVKKCAVYFASDPPSKLDIGRFQITTQSRQLILRDNVIERKLLVKDTt
| |... | .. ..| .||||..| .||| . . ..| |.|.. | .||| |. | .| | . . |. |.|| .| .
inadyvvfpdeeadlkyilaqGplsatvddfwtlvaeqdvrvivmvaklqedGrdkcapywpsvvqerlkagdvvveflsstsdefdrviltelqliyr.
gkFEPKTVTHYQHVKWPDRDTPKT--HVDT
| . |.| |.. ||| | ..
..sesrvvrhvqflswpdhGvpsdledlvr
|
|||||||||
0049260 | (Phosphotyrosine protein) phosphatases II | 1227-1417 | 4e-33 | 109.6 | In-house | 2-142 (152) | alignment | ||
Range on Protein: 1227-1417
Range on HMM: 2-142/152.0
IPTHGHPHRFIATQGPLDNTCEDFWAMCVYHNVDKIAMLCLNVEKNVKKCAVYFasdppskldigrfqittqsrqlilrdnvierkllvkdttgkfepkt
|. ...|..|||||||..||..||| | .... | ||. .|.. ||. |.
idgyampfefiatqgpgpntladfwrmlkelgittivmltellelgklkceqyi..............................................
vtHYQHVKWPDRDTPKTHVDTFELMELV----KKSENPIVVHCSAGIGRTTAFIGTEYLArevendPKIELTEALKHLREHRWKGVQMRSQLYWM
.|.|. ||| .|. . .|.... .....|..||||||.||| ... .. ...| ||....||.|...|. .||..
..qylhlpwpDhgvpdlsqlllflllfieklaldkggpvlVHCsaGvgRtgtlvaaylml......lgvsleeavalvrekRpgavpnpgqlrfl
|
|||||||||
subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 1230-1419 | 1.1e-21 | 72.1 | In-house | 47-234 (239) | alignment | ||
Range on Protein: 1230-1419
Range on HMM: 47-234/239.0
HGHPHRFIATQGPLDNTCEDFWAMCVYHNVDKIAMLCLNVEKNVKKCAVYFAsDPPSKLdiGRFQITTQsRQLILRDNVIerKLLVKDTTGKFEPKTVTH
| |. .||||| . .. ||| | | || .| ||| |. | || ...| . . .. | .| . .| |. | . | .
dgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywp.dstsky..cnlrvtlr.ktevfadyii..rtfvmsqvgqteeryvyq
YQHVKWPDRDTPKTHVDTFELMELVKKS----ENPIVVHCSAGIGRTTAFIGTEYLAREVENDPKIELTEALKHLREHRWKGVQMRSQLYWMTL
|. |||. |. . | . | | |.|||||.||| ||. . . |. ... ... . .| .|| | . || | .. |
yhftvwpdkgvpqyatavlglrrkitkdslpgarpwvihcsagvgrtgaflvidamlrqakkqktvdifnyvkairedrphmvqtseqyvfihl
|
|||||||||
subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 1230-1419 | 1.2e-21 | 71.9 | In-house | 48-235 (239) | alignment | ||
Range on Protein: 1230-1419
Range on HMM: 48-235/239.0
HGHPHRFIATQGPLDNTCEDFWAMCVYHNVDKIAMLCLNVEKNVKKCAVYFAsDPPSKLdiGRFQITTQsRQLILRDNVIerKLLVKDTTGKFEPKTVTH
| |. .||||| . .. ||| | | || .| ||| |. | || ...| . . .. | .| . .| |. | . | .
dgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywp.dstsky..cnlrvtlr.ktevfadyii..rtfvmsqvgqteeryvyq
YQHVKWPDRDTPKTHVDTFELMELVKKS----ENPIVVHCSAGIGRTTAFIGTEYLAREVENDPKIELTEALKHLREHRWKGVQMRSQLYWMTL
|. |||. |. . | . | | |.|||||.||| ||. . . |. ... ... . .| .|| | . || | .. |
yhftvwpdkgvpqyatavlglrrkitkdslpgarpwvihcsagvgrtgaflvidamlrqakkqktvdifnyvkairedrphmvqtseqyvfihl
|
|||||||||
subfamily_PTPN14_pd | Subfamily PTPN14 | 1231-1414 | 2.2e-27 | 90.9 | In-house | 90-285 (300) | alignment | ||
Range on Protein: 1231-1414
Range on HMM: 90-285/300.0
GHPHRFIATQGPLDNTCEDFWAMCVYHNVDKIAMLCLNVEKNVKKCAVYFASD--PPSKLDIGRFQITTQSRQLilRDNVIERKLLVKDTTGKfEPKTVT
|. . .|..||||..|..||| | ..|. |.|| . |. .|. || .. .... |.|..||. .. | || ..| .| | | .||
gkersyivaqgPleltvqdfWqmvWeqgvqlivmlteeeedgkeksfkyfPkleskkktvefgkfkvttkfsed..sdsvittglklkhlpsk.eertvw
HYQHVKWPDRDTPKTHVDTFELMELVK-------------KSENPIVVHCSAGIGRTTAFIGTEYLAREVENDPKIELTEALKHLREHRWKGVQMRSQL
| |.. |||.. |. . .. .| |. .|. |..||||||.||| | .. | .|.. .|.. ..|..||| | || .|
hlqytDWpdhgvPeDvkgflsyLeevqsvrrktnseveskeskPPvlvhCsaGvGrtGvlilsdlliatlehneeidikkvlarLreqrmllvqtlaqY
|
|||||||||
subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 1232-1282 | 1.5e-06 | 21.8 | In-house | 105-155 (349) | alignment | ||
Range on Protein: 1232-1282
Range on HMM: 105-155/349.0
HPHRFIATQGPLDNTCEDFWAMCVYHNVDKIAMLCLNVEKNVKKCAVYFAS
...|||| || | .||. . . .| . | . |....|| .|.
vekkyiatqaPlPstvddfykvillngvklvlsLnddkelslekcdiywqe
|
|||||||||
subfamily_Anemone-PTP-3_pd | Subfamily Anemone-PTP-3 | 1234-1404 | 5.6e-14 | 46.8 | In-house | 5-183 (199) | alignment | ||
Range on Protein: 1234-1404
Range on HMM: 5-183/199.0
HRFIATQGPLDNTCEDFWAMCVYHNVDKIAMLCLNvEKNVK-KCAVYFASDPPSKLDIGRFQITTQSRQlILRDNVIERKLLVKDTTGKFEPKTVTHYQH
.|.|||| || .| ||| | .| |. . .|| . ..|... . | . .||.. | .| .|...|| . ..|||
rryiatqhplretmadfwqmvwetgsghivmvndd.qknkeadypfywpttesgtgkygslsvttktit.tkpdytitaliltnnttappstreishyqf
VKWPDRDTPKTHVD-TF--ELMELVKKSE----NPIVVHCSAGIGRTTAFIGTEYLAREVEND--PKIELTEALKHLREHR
| .. ||. . | |. || | |..|||| | | | |. . | |. ..| | | ||. |
tswkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqar
|
|||||||||
subfamily_Nvec-PTP-3_pd | Subfamily Nvec-PTP-3 | 1234-1404 | 7.2e-14 | 46.4 | In-house | 4-182 (198) | alignment | ||
Range on Protein: 1234-1404
Range on HMM: 4-182/198.0
HRFIATQGPLDNTCEDFWAMCVYHNVDKIAMLCLNvEKNVK-KCAVYFASDPPSKLDIGRFQITTQSRQlILRDNVIERKLLVKDTTGKFEPKTVTHYQH
.|.|||| || .| ||| | .| |. . .|| . ..|... . | . .||.. | .| .|...|| . ..|||
rryiatqhplretladfwqmvwetgsghivmvndd.qknkeadypfywpttesgtgkygslsvttktit.tkpdytitaliltnnttappstreishyqf
VKWPDRDTPKTHVD-TF--ELMELVKKSE----NPIVVHCSAGIGRTTAFIGTEYLAREVEND--PKIELTEALKHLREHR
| .. ||. . | |. || | |..|||| | | | |. . | |. ..| | | ||. |
tswkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqar
|
|||||||||
subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 1234-1282 | 1.3e-10 | 35.6 | In-house | 104-152 (350) | alignment | ||
Range on Protein: 1234-1282
Range on HMM: 104-152/350.0
HRFIATQGPLDNTCEDFWAMCVYHNVDKIAMLCLNVEKNVKKCAVYFAS
...||||.|| .| .||. ... .| | .| .|| |..|| |.
fkYiatqaPlpstvddfykvillnkvkvilsltsdvelnlekcyrYWqe
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 1234-1295 | 8.1e-06 | 19.4 | In-house | 236-293 (440) | alignment | ||
Range on Protein: 1234-1295
Range on HMM: 236-293/440.0
HRFIATQGPLDNTCEDFWAMCVYHNVDKIAMLclNvEKNVKKCAVYFASDPPSkLDIGRFQI
||||| ||| | ||| . ... | || | . | | |..|. . | . .| | .
nafiatqmpldstvldfwrlvhdyristiiml..n.qlndktcsiywpvntrs.vtfgpftv
|
|||||||||
subfamily_PTPN23_pd | Subfamily PTPN23 | 1235-1416 | 3.2e-27 | 90.1 | In-house | 84-271 (288) | alignment | ||
Range on Protein: 1235-1416
Range on HMM: 84-271/288.0
RFIATQGPLDNTCEDFWAMCVYHNVDKIAMLCLNVEKNVKKCAVYFASDPPSKLDIGRFQITTQSRQLilRDNVIERKLLVKdTTGKFEPKTVTHYQHVK
|||||.||..| ||| | . . | || . |.. .|.. |. .| | ...| .| . ....||.| .. | .. . |.|.| | .
dfiatqaPlqstlnDFWlmvyeqkssviVmllskeelgkpkvdrYwPedkgetvkfgdlsvtlksvre..tethvervlkle.tldadavksvshlqlts
WPDRDTPKTHVDTFELMELVKK--------SENPIVVHCSAGIGRTTAFIGTEYLAREVENDPKI-ELTEALKHLREHRWKGVQMRSQLYW
||. |.. . ..... |.. |. |.|||||||.||| .| .||.|... . .. . ...||| | || ..||
WpelGvPasPetllqfldevesayeavqrksktPlvvhCsaGvgRtgvfalvyaavrelekgnglldiiqvvsrlreqRrfmvqekeqlkf
|
|||||||||
subfamily_PTPRN_pd | Subfamily PTPRN | 1235-1422 | 4.2e-22 | 73.2 | In-house | 101-288 (297) | alignment | ||
Range on Protein: 1235-1422
Range on HMM: 101-288/297.0
RFIATQGPLDNTCEDFWAMCVYHNVDKIAMLCLNVEKNVKKCAVYFASDPPSKLDIgrFQITTQSRQlILRDNVIERKLLVKDTTGKfEPKTVTHYQHVK
.||||||| .| ||| | . | | .|. |..||.|. |. . . .| ... | | |. . | . .|. . | .||| . ..
ayiatqgplastvadfwqmvweqGvvvivnltrleeegvkqckrywpdeGsevyhi..yevhlvseh.iwcddylvrsfylknlqts.etrtvtqfhfls
WPDRDTPKTHVDTFELMELVKKS----ENPIVVHCSAGIGRTTAFIGTEYLAREV-ENDPKIELTEALKHLREHRWKGVQMRSQLYwMTLGAV
||....| . .|. | || |||||||.| ||| ..| . . . .|... .|.|||. | . |. ..|. ..|.||
wpeegvPasaksllefrrkvnksyrGrscpivvhcsdGaGrtGvyilidlvlnrllkGvkeidiaatlehlrdqrpglvktkdqfe.faltav
|
|||||||||
subfamily_eak_pd | Subfamily eak | 1235-1363 | 8.9e-10 | 32.5 | In-house | 94-216 (332) | alignment | ||
Range on Protein: 1235-1363
Range on HMM: 94-216/332.0
RFIATQGPLDNTCEDFWAMCVYHNVDKIAMLCLNVEKNVKKCAVYFASDPPSKLDIGRFQITTQSRqlILRDNVIERKLLVKDTTgkfEPKTVTHYQHVK
..| | . .. || | . . | .| .||....| || . .|. | ....... . |... |.| .. | . | ||.
kyiltGiasedkvfafwqmvleqkspaivqlledvelkleksdkyfpdktreelkfGildverkef..vkrniletrllelskGn...ethrvlhykvfG
WPDRDTPKTHvDTFELMELVKKSENPIVV
| . ..|| . | . | . .|. . ..
wtettlpkye.dflalrkvmkevGvllli
|
|||||||||
subfamily_Cele-PTP-7_pd | Subfamily Cele-PTP-7 | 1241-1419 | 1.1e-21 | 71.5 | In-house | 98-282 (302) | alignment | ||
Range on Protein: 1241-1419
Range on HMM: 98-282/302.0
GPLDNTCEDFWAMCVYHNVDKIAMLCLNVEKNVKKCAVYFASDPPSKLDIGRFQITTQSRQLILRDNVIERKLLV------KDTTGKFEPKTVTHYQHVK
| .|.| .||. .|| .. || ||.. |||| |.. . .| ||. ..| | . | . ... . . . | .||| ..
vpkkstlekhwalieqynvaivvqlcsfvedeekkcaeyysdkvggelkfgrytvktvsvktdleeftdkksfklytveiknekkkkkvkktvdilafsa
WPDRDTPKTHVDTFELMELVKKSENPIVVHCSAGIGRTTAFIGTEYLAREVENDPKIELTEALKHLREHRWKGVQMRSQLYWMTL
||| .|| ..... . . ..||||||.||| ... | .. .| . .. .|. |. || .|| .. |
wpdhGapkeaytaldilkfcesykknvlvhcsaGvGrtGtlvaikyGiqlcskkkvtdllsivlpvrqcryGavqdeqqliylll
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subfamily_hpo-7_pd | Subfamily hpo-7 | 1245-1404 | 1.4e-23 | 78.2 | In-house | 45-206 (263) | alignment | ||
Range on Protein: 1245-1404
Range on HMM: 45-206/263.0
NTCEDFWAMCVYHNVDKIAMLCLNVEKNVKKCAVYFASDPPSKLDIGRFQITTQSRQLilrDNVIERKLLVKDTTGKFEPKTVTHYQHVKWPDRDTPKTH
.| . |. . | . ....||| |..|.|| || . |. . ...| | | .. . |.. | . .||.||... |... |.
qtidkfyqtivqtktevvvmLcDfneegvekcssyfPlekdekqklanvnvcttkvqs...dvllktlellstlgeKkkthtvkhysykgWiekndpela
VDTFELMELVKKSeNPIVVHCSAGIGRTTAFIGTEYLAR----EVENDP--KIELTEALKHLREHR
. .........| ..|||||.||||. || .| . . ... . ... . |..||..|
reilnilkvarns.kslvvhcstGiGrsaafsvaElvyqkmirsldttstveldylsLleelrssr
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subfamily_Cele-PTP-9_pd | Subfamily Cele-PTP-9 | 1246-1406 | 7e-25 | 82.5 | In-house | 40-202 (255) | alignment | ||
Range on Protein: 1246-1406
Range on HMM: 40-202/255.0
TCEDFWAMCVYHNVDKIAMLCLNVEKNVKKCAVYFASDPPSKLDIGRFQITTQSrqlILRDNVIeRKLLVKDTTG-KFEPKTVTHYQHVKWPDRDTPKTH
| . |. . | . ....||| |..|.|| || . || . ..|| | |. | | . | | | . .||.||.. |... .|.
tvdkfyqtivqtktevvvmlcdfaeegvekcssyfplekdeklkladvnvtttk...ssadvvl.rtleitstlgekkkthtvkhysykGWieknaPela
VDTFELMELVKKSeNPIVVHCSAGIGRTTAFIGTEYLAR----EVENDP--KIELTEALKHLREHRWK
. ... .|..| ..|||||.||||..||. .|.. . ... . ... . |..||..| .
reilnilkvvrds.ksvvvhCstGiGrsaafvlaelvyqkmirsldttetveldylslleelrskrkr
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0048076 | (Phosphotyrosine protein) phosphatases II | 1317-1418 | 4.2e-20 | 67.3 | In-house | 37-136 (145) | alignment | ||
Range on Protein: 1317-1418
Range on HMM: 37-136/145.0
DTTGKFEPKTVTHYQHVKWPDRDTPKTHVDTFELMELVKKS---ENPIVVHCSAGIGRTTAFIGTEYLARevendPKIELTEALKHLREHRWKGVQMRSQ
.. ... .....|... |||...| . . |..|.... ..|..||||||.|||..... . . .. | |||...|..|...|. .|
tselellerlgiqylylpwpDhgvpdllellleflefieealkeggpvlVHCsaGvgRtgtlvaaylmll.....lgvsleealelvrsqrpgavpnpgq
LYWMT
|...
lrfly
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0048179 | (Phosphotyrosine protein) phosphatases II | 1318-1417 | 1.3e-18 | 62.6 | In-house | 40-137 (144) | alignment | ||
Range on Protein: 1318-1417
Range on HMM: 40-137/144.0
TTGKFEPKTVTHYQHVKWPDRDTPKTHVDTFELMELVKKS---ENPIVVHCSAGIGRTTAFIGTEYLArevenDPKIELTEALKHLREHRWKGVQMRSQL
|. .....|.|. |||...| . |..|.... ..|..||||||.|||.... . .. | |||...|..|. .|. ..||
yepefleregiqylhlpwpDhgvpdllellleflefieealeeggpvlVHCsaGvgRtgtlvaaylmk.....klglsleealalvrsrrpgavpnpgql
YWM
...
rfL
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subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 1322-1416 | 1.9e-09 | 31.4 | In-house | 86-185 (440) | alignment | ||
Range on Protein: 1322-1416
Range on HMM: 86-185/440.0
FEPKTVTHYQHVKWPDRDTPKTHVDTFELMELVKKS-----ENPIVVHCSAGIGRTTAFIGTEYLAREVENDPKIELTEALKHLREHRWKGVQMRSQLYW
| .|. .|.. |||. || ..... |..| . |..|||||| ||| | . . ||.. .|.. .. .|. | . || | .
iesrtlkqyhyqgwpdkgvpkfagpvlkmiqdvnesqekagngpllvhcsagagrtgviiavdsilreakrsdqidifsfinsmrnnrpqmvqtpeqyaf
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subfamily_PTPDC1_pd | Subfamily PTPDC1 | 1322-1415 | 6.5e-07 | 24.0 | In-house | 78-166 (182) | alignment | ||
Range on Protein: 1322-1415
Range on HMM: 78-166/182.0
FEPKTVTHYQhVKWPDRDT--PKTHVDTFELMELVKKSEnPIVVHCSAGIGRTTAFIGTeYLAREVendpKIELTEALKHLREHRWKGVQMRSQLY
. . ...|. . |.| .. .. .| ... . . . . ||| || ||| | . || ... .|.| .|..| | .| |.|.
lmeqgiyvyn.fgwkDygvasleriLdivkvvafalqeg.kvavhChaGlGrtGvliac.ylvyak....rltaekaiklvrskrpksiqtreqve
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PTPc_DSPc_SM00012 | 1326-1414 | 2.7e-20 | 67.9 | In-house | 1-96 (105) | alignment | |||
Range on Protein: 1326-1414
Range on HMM: 1-96/105.0
TVTHYQHVKWPDRDTPKTHVDTFELMELVKKSEN------PIVVHCSAGIGRTTAFIGTEYLAREVEND-PKIELTEALKHLREHRWKGVQMRSQL
||.||.. .||| .|.. . .||.. |||..| |.|||||||.||| |. ..| . .|. .... . .|.||..| . ||. |
tvkhyhytgwpdhgvPeesdsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgmvqteeqy
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0038934 | (Phosphotyrosine protein) phosphatases II | 1326-1419 | 1.3e-08 | 30.2 | In-house | 78-169 (194) | alignment | ||
Range on Protein: 1326-1419
Range on HMM: 78-169/194.0
TVTHYQHVKWPDRDTPKTHVDTFELMELV-----KKSENPIVVHCSAGIGRTTAFIGTeYLAREVendpKIELTEALKHLREHRWKGVqmRSQLYWMTL
.| . .||. |. . ... ..|| ..... ..||| ||.||| ... || .. . ||....|| | ... ..| |. |
agieylklpfpddgtvPsleillrfldlvdeflnedpggvvaVHCkaGlgRtGtlvaa.YLiyrl....gmsaeeAialfrekRpgai..pnqdyleal
|
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PTEN_1 | 1329-1416 | 4.8e-09 | 31.3 | In-house | 96-184 (196) | alignment | |||
Range on Protein: 1329-1416
Range on HMM: 96-184/196.0
HYQHVKWPDRDTPKTHVDTFELMELVKK-----SENPIVVHCSAGIGRTtAFIGTEYLAREVEndpkIELTEALKHLREHRWKGV-QMRSQLYW
| |. ..| .| . .. .. ..| ..||| ||.||. ... || . |||...||.|..| ...|| .
eylhfpieDhgapslselfdicksfiewllsdpngnvVlVHCkaGlgRs.GtvvaayLmykgk....ltadeAlelvrekRppgapnspsqerl
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PTPc_motif_SM00404 | 1346-1410 | 6e-06 | 21.2 | In-house | 68-126 (140) | alignment | |||
Range on Protein: 1346-1410
Range on HMM: 68-126/140.0
DTFELMELVKKSENPIVVHCSAGIGRTTAFIGTEYLAREvendpKIELTEALKHLREHRwKGVQM
. . .| ..|.. ..||| ||. |. ..| ... .. ...| ||.. ..| | . ..
kvldfienaekkggkvlVHCqaGvSRSatliiaYlmryr.....qlslaeayefvkerR.piisp
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subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 1353-1386 | 1.2e-06 | 22.5 | In-house | 257-290 (350) | alignment | ||
Range on Protein: 1353-1386
Range on HMM: 257-290/350.0
LVKKSENPIVVHCSAGIGRTTAFIGTEYLAREVE
| .. .||.||||||.||| .. ..| ..|
ldnarsspilvhCsaGvGrtGtlvtlDsllsdfe
|
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subfamily_PTEN_pd | Subfamily PTEN | 1354-1416 | 4.6e-06 | 21.7 | In-house | 110-171 (184) | alignment | ||
Range on Protein: 1354-1416
Range on HMM: 110-171/184.0
VKKSENPIVVHCSAGIGRTTAFIGTeYLAREVENDPKIELTEALKHLREHRWKGVQMRSQLYW
....| .|||| || ||| | . || . . . | .| .. | . |||.. ||. .
eedkknvvvvHCkaGkGRtGvliva.yllkslllekaeealelfaeaRtknkkgvtiPsqrRY
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subfamily_CG42327_pd | Subfamily CG42327 | 1355-1416 | 3.4e-07 | 24.2 | In-house | 244-306 (319) | alignment | ||
Range on Protein: 1355-1416
Range on HMM: 244-306/319.0
KKSENPIVVHCSAGIGRTTAFIGTEYLAREVEND-PKIELTEALKHLREHRWKGVQMRSQLYW
..| |.||||| |.||| | .. |..|. ... . . ..|. | . |. . | .
resqGPlvvhcsdGvGrtGlviasdiairsleeskrsvdiPqlvssvrrdrasavltkeqyef
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subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 1358-1414 | 3.1e-06 | 21.3 | In-house | 228-284 (297) | alignment | ||
Range on Protein: 1358-1414
Range on HMM: 228-284/297.0
ENPIVVHCSAGIGRTTAFIGTEYLAREVENDPKIELTEALKHLREHRWKGVQMRSQL
. ...||||||.||. . .. .. . .. . . |..||| | . || |
nayllvhcsaGvGrsGvvvlsdvilaklrkkripdvaailsilreqrarlvqtleqf
|