Synonym: CELE_Y39B6A.18, CELE_Y39B6A.18
Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
| Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
|---|---|---|---|---|---|---|---|---|---|
| WSN | Domain of unknown function | 27-93 | 9.4e-27 | 82.7 | Pfam-A | 2-68 (69) | alignment | ||
Range on Protein: 27-93
Range on HMM: 2-68/69.0
KPTDYLDHITIIAHIANGITLQAGLMNGTIQIDEVVGEMLNLGSANVSDLINYKPDKILELIKKLKE
.....|....|||...|||.|||||.||.| ||.|. |.||.||...|.|.....||. | ..||.|
elqtvleklsiiaRvtngIyLqaglingsipiddviaELLnigssslsqllkidvdklkeklnklse
|
|||||||||
| DUF2763 | Protein of unknown function (DUF2763) | 742-811 | 6.7e-06 | 13.0 | Pfam-A | 19-86 (91) | alignment | ||
Range on Protein: 742-811
Range on HMM: 19-86/91.0
QNVPSAFQSFDNFLQLFFASQQTISVPPPNPQSNSGGVNTGGTGNGNGSGGpsGDTGTGPTGSGTGTGAA
. . | .. .|..||| . . | .. ...| . . ... |.| .| | . |. | | | |
siivdfflgilefislFFrtllspevekarrknssskkkiddgrGgpgapg..Ggrrlgrigggggpsap
|
|||||||||
| MFS_1 | Major Facilitator Superfamily | 805-877 | 5.8e-06 | 11.5 | Pfam-A | 127-189 (352) | alignment | ||
Range on Protein: 805-877
Range on HMM: 127-189/352.0
GTGTGAAAAVGSSTVSTVSdESSDFPILFVVIPVVLILVALviggiVFIWYRKREEKRKEKEAEEENEkliaE
..|....|..| . .. .| .. .|... .|..|.|. .|... .|..........| |
sagfslGailgpllgglla.sslgWravfyilaivsllaav.....lfllllpeepperkrkspkeee....g
|
|||||||||
| TMEM154 | TMEM154 protein family | 811-871 | 2.1e-07 | 22.4 | Pfam-A | 37-99 (146) | alignment | ||
Range on Protein: 811-871
Range on HMM: 37-99/146.0
AAAVGSSTVSTVSDES--SDFpILFVVIP-VVLILVALVIggIVFIWYRKREEKRKE--KEAEEEN
.| |... .. ... .. .| ..|| |||||. ||. .... ..|| ...| .| |.|.
sanvnleegelseksadqael.vlmiiiPsvvLillllvv..vilvikkkrkrrKqeetsedeked
|
|||||||||
| DUF3377 | Domain of unknown function (DUF3377) | 818-857 | 5.6e-06 | 16.1 | Pfam-A | 18-57 (74) | alignment | ||
Range on Protein: 818-857
Range on HMM: 18-57/74.0
TVSTVSDESSDFPILFVVIPVVLILVALVIGGIVFIWYRK
.| .|.|.|. .. ||||.|| | ||. .. ||
ivvevddvsgtvnavaVviPlvLalCiLvlvytivqfkrk
|
|||||||||
| DUF1510 | Protein of unknown function (DUF1510) | 831-943 | 2.5e-06 | 16.3 | Pfam-A | 15-125 (217) | alignment | ||
Range on Protein: 831-943
Range on HMM: 15-125/217.0
ILFVVIPVVLILVALVIGGIVFIWYRKREEKRKEKEAEEENEKLIAERERMRAIKEEEeRVKAEREK-----VKKEEERLKAEEEKVKVEKernkekVKA
.| . | .|..|...| . ... . .......|.|.|..... .| |.. ..|. ....|. |.||.. ..|||| |.|. .
vLniaiaiVvvlivivaaqllvgnskskkasadeeeeeksedeekteeeevkeeekea.akdedkeddsesekkdeeseeeeeeekekkee......ese
EEERLKAEEEKVKIEKEK
|.|. ..|.|. ..|||
edeketeekeesnvekei
|
|||||||||
| 0045450 | (Phosphotyrosine protein) phosphatases II | 1005-1278 | 4.8e-59 | 195.9 | In-house | 7-295 (307) | alignment | ||
Range on Protein: 1005-1278
Range on HMM: 7-295/307.0
KLLKVKKVELWTMSLPNKDDHKPAKFYNttiENVNVTTIDKDHITESYAYLPEDKHRYPTVPCKPSTAVEVIVDGK----RAPIHANWV--------PTP
......| .|. . |. .. .. .| .. . ..||... ....... . ||.||. ... ..| | . . .. |.|..| ...
lfidalkllllvllllldfltgllkefe...kllsvtvfllgeysiallpenkdknrykdilpydhtRVklssldgsledsdYiNAsyvrvpllllldgy
GHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMWpRNDLQVGRFMIKMTNMDFivQKNIMRRSFKVADSTGKFAARTLTHY
....|||||.| . |.|||| |. .. |..|||. . ||..... | | . |. |.| ....... .... .| ..| |. |.. ||.||.
dlkrkfIatqgPlpetvedFwrmlweqgvtvivmltelvelgrekcaqywPde.geeltygnftvtllseeh..ldgytvrtlevtdldgtgesrtvthf
QYSQWAERGVPKSHVETYELMEMVKK------SEKPIVVHCSNGIGRSMAFIGTEYLARQVEADPT---IELTEALKHLHEHRWNGVQTNSQLYW
.| | . |||.| |. ...|.|.| ...|..|||| |.||...||. .. ||.|...| . | ||.|.| |.|...||. .|...
hytgwpdhgvppsfeelldfieevrkaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrf
|
|||||||||
| subfamily_Cele-PTP-19_pd | Subfamily Cele-PTP-19 | 1008-1306 | 1.1e-179 | 590.6 | In-house | 2-300 (301) | alignment | ||
Range on Protein: 1008-1306
Range on HMM: 2-300/301.0
KVKKVELWTMSLPNKDDHKPAKFYNTTIENVNVTTIDKDHITESYAYLPEDKHRYPTVPCKPSTAVEVIVDGKRAPIHANWVPTPGHPHRFIATQSPINA
||||.|.|..| ..|||.|.|||||||||||||||||||||||||||||.||||||||||||||||||||||||.||||||.||.||||||||||.|...
kvkkiekwiiskdfkdddktakfynttienvnvttidkdhitesyaylpkdkhryptvPckPstavevivdGkrvPihanwiptsGhphrfiatqgPlkn
TCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMWPRNDLQVGRFMIKMTNMDFIVQKNIMRRSFKVADSTGKFAARTLTHYQYSQWAERGVPKSHV
|.||||||..||.||.|||.|.|||........|||......|..|||.||..|...|..|.|..|...|.|||||||.||.||||||.|..|||||||.
tsedfwamlvqydvekivmlgqkvekleekceeylpvkisekldigrfkikiknkelilnkkiskrtlevedstgkfatrtvthyqysewtdrgvPksha
ETYELMEMVKKSEKPIVVHCSNGIGRSMAFIGTEYLARQVEADPTIELTEALKHLHEHRWNGVQTNSQLYWMTLGTMYRLIKEYGFDMKIYDQQMAMFN
|...|||.|||||||||||||.|||||.||||||||||.||||||||||||||||.||||||||||||||||||||.||||||||||||||..|.|||.
elfdlmelvkksekPivvhcsaGiGrsvafigteylareveadptieltealkhlrehrwngvqtnsqlywmtlGtvyrlikeygfdmkiyeeqlamfd
|
|||||||||
| subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 1025-1277 | 5.1e-30 | 99.4 | In-house | 16-268 (287) | alignment | ||
Range on Protein: 1025-1277
Range on HMM: 16-268/287.0
HKPAKFYNTTIENVNVTTIDKDHITESYAYLPEDKHRYPTVPCKPSTAVeVIVDGKRAPIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHI
.| . ... .. | ..|..| . | .|| |. . . | .. . . | | .. . . ..||...||. | .|| . . .|. |
akgnegfknqftvleqvtqredevthniasqnkdknRltqilvpdnyrv.llkgehpdyinavfidgykekkafiiaesPmfntarnfWkliddrnvtai
VMVGRKVEYWKNIHNDYlpmWPRND-LQVGRFMIKMTNMDfiVQKNIMRRSFKVADSTGKFAARTLTHYQYSQWAERG-VPKSHVETYELMEMVKKS---
||. .. | ... .| || .. . .| . |...| . |... . | ..| .. . . .... ||. .| ..| |.. . ||.|.
vmlcqekendeevcyqy...WpeeksvvlGeyniellnee..vnagyierklevknknkagdkqqvkqyqitnWdstgkvtepqtillvieemyktqrkr
-EKPIVVHCSNGIGRSMAFIGTEYLARQVEADPTIELTEALKHLHEHRWNGVQTNSQLY
. .||||||...||| |. . .... . .|.. . ||. . . ||| .|
gntsivvhCsdtvGrsamfcaaattinkckteGviDvfqvlksqriqkpgsvqtveqyk
|
|||||||||
| subfamily_Sponge-PTP6_pd | Subfamily Sponge-PTP6 | 1031-1278 | 7.4e-21 | 69.1 | In-house | 22-270 (439) | alignment | ||
Range on Protein: 1031-1278
Range on HMM: 22-270/439.0
YNTTIENVNVTTIDKDHITESYAY-LPEDKHRYPTVPCKPSTAVEV-IVD--GKRAPIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVM
.. |..| | | |. | . | || | | | . . . | ||.. .. .|||| | . |..||| . .. . .|||
fkeifekinstspdyaciaslaaqeydqtknrykdvgafdhtrvtlqeipgvphshyinanyikGyyddklyiatqgpkkettddfwrlviekktvtivm
VGRKVEYWKnihndylpMWPRNDLQV-GRFMIKMTNmdFIVQKNIMRRSFKVADSTGKF-AARTLTHYQYSQWAERGVPKSHVETYELMEMV-----KKS
. || .| || .. . | .... | | . | ||| . . ||. ...| | .. || ... . |.
ltnlvesyk........ywpsdaevcygdiavrvdr..nielpnyvirgfkvfnerdttekertvlqfhyiawpdknvpaqashvldflrainsandkee
EKPIVVHCSNGIGRSMAFIGTEYLARQVEADPTIELTEALKHLHEHRWNGVQTNSQLYW
|.||||| |.||. . | . |. .. ... .| |...| . ||. | .
ygpvvvhcsagvGrtGtiialdialeqlklenkvdikgivkvlrkqrkqmvqalcqyvf
|
|||||||||
| 0040438 | (Phosphotyrosine protein) phosphatases II | 1032-1292 | 1.6e-60 | 200.4 | In-house | 19-276 (317) | alignment | ||
Range on Protein: 1032-1292
Range on HMM: 19-276/317.0
NTTIENVNVTTIDKDHITESYAYLPEDKHRYPTVPCKPSTAVEVIVDGK---RAPIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVG
| .. ....|...... . ||.||| ... ... | . ..|. |.|..|..| ....|||||.| . |.|||| |.... |..|||.
alleefedllslkldtysvaelpenkdknrypdilpydhsRVkLsplggdldsdYInAsyvdgpnlkrkfIatqgPlpntvedFwrmvweqgvtvivmLt
RKVEYWKNIHNDYLPMwpRNDLQVGRFMIKMTNMDFivQKNIMRRSFKVADStGKFAARTLTHYQYSQWAERGVPKSHVETYELMEMVKKS----EKPIV
. .|.... | |. .. |..|.|........ ..| | ..| |. |. ||.||..| | . |||.|. . ...|.|... ..|..
eleelgrekcaqYwpl..getltygdftvtllseee..lagitlrtlevedl.gdsesrtvthfhytgWpdhgvppspdllldfleavrealedpggpvl
VHCSNGIGRSMAFIGTEYLARQVEADPTIELTEALKHLHEHRWNGVQTNSQLYWMtlgtmYRLIKEYG
||||.|.||...||. ... .|.| .. ..||.|.| |.|...||| .|.... |... ||
VHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrfl.....ydalleyl
|
|||||||||
| 0043336 | (Phosphotyrosine protein) phosphatases II | 1034-1278 | 7.8e-53 | 175.1 | In-house | 23-268 (278) | alignment | ||
Range on Protein: 1034-1278
Range on HMM: 23-268/278.0
TIENVNVTTIDKDHITESYAYLPEDKHRYPTVPCKPSTAVEVIVDGKR---APIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRK
| .......|... .. . ||.||. ... ... | . ..|.. |.|..|... .|..||||| | . |.|||| |. .. |..|||. .
llefeellsfkldtysiallpenkdknrykdilpydhsrvklsllggdldsdYinAsyvdgynvprkfiatqgPlpetvedFwrmvwelgvttivmLtel
VEYWKNIHNDYLPmwpRNDLQVGRFMIKMTNMDFivQKNIMRRSFKVADSTGKFAaRTLTHYQYSQWAERGVPKSHVETYELMEMVKK----SEKPIVVH
||.... | | .. |..|.| ....... ......| ..| . .. || |||.| | . ||| | .....|.. |..|..||
velgrvkcaqYwp...ggsltygdftvtllkeeh..lddytvrtlevtnlgdges.rtvthyhylgwpdhgvpeslsllldflkavrealedsngpvlVH
CSNGIGRSMAFIGTEYLARQVEADPTIELTEALKHLHEHRWNGVQTNSQLYW
||.|.||...||. ..| .|.| .. | ||.|.| |.|.. ||| ||...
CsaGvgRTGtfialyllleqlekeggvdleeavkelreqRpgavqtpsqyrf
|
|||||||||
| 0049772 | (Phosphotyrosine protein) phosphatases II | 1034-1279 | 4.9e-20 | 67.9 | In-house | 24-272 (314) | alignment | ||
Range on Protein: 1034-1279
Range on HMM: 24-272/314.0
TIENVNVTTIDKDHITESYAYLPEDKHRYPTVPCKPsTAVEVivD-----GkRAPIHANWVPTPghpHRFIATQSPINATCEDF----------WAMC--
.. ... ... . .|. .. .| || ||. ... . . | . . | . |.|..| .. .||||| | . |..|| | |
vlnrrslsvlpeltilvadlflnrdknryldilpad.nrvil..pglpvsg.sdyinasyvdgf...lkfIatqgpleitvvdfreepvlyyngwrmvlr
MQYEVEHIVM---------------------VGRKVEYWknihndylPMWPRNDLQVGRfmikmtnmdfivqknimrrsfKVADSTgKFAARTLTHYQYS
.. | ||| . .. .... ||. . .. .. .. |. .| .
gdlnvrdivmsrdevladelsrLdaAlgKtpllildgng........neptaadlellk.....................eelydp.elferlgikylri
QWAERGVPkSHVETYELMEMVKK--SEKPIVVHCSNGIGRSMAFIGTEYLARQVeadpTIELTEALKHLHEHRW-----NGVQTNSQLYWM
. ..| . .|..|.... ..|..|||. |.||. |. . || .. . | |||..... | . ... |....
pvpDgsap.lledfdeflefieeadkggpvlvHCkaGkgRtgtfvvaaylmkll....gvsleealedvrlkRpinpnpgfieqleqyefi
|
|||||||||
| subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 1035-1276 | 5.3e-17 | 56.7 | In-house | 12-248 (267) | alignment | ||
Range on Protein: 1035-1276
Range on HMM: 12-248/267.0
IENVNVTTIDKDHITESYAYLPEDKHRYPTVpcKPSTAVEVIVDGKRAP-IHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKveY
|... . .. |. |.| ....|. . | ||. | | | .| . . ||.|| |.. | ||. . ....| ||.. . .
felikkisdtsstisqsiaeknqernrlddn..lpyddtrvilrtkeeeyinasyvegyktknafivtqdplkntitdfltvihdqkvpvivlltkv..f
WKNIHNDYLPM----WPRNDLQVGRFMIKMTNMDFIVQKNImrrSFKvaDStgkfAARTLTHYQYSQWAERGVPKSHVETYE-L--MEMVKKSEKPIVVH
||. . | .|| | . . | | |. .. || . .|. .| | | .| | ... . . ... ..|.||.
tdnirlfwPPkmgqakkyqdltvehslekeendyqiitlel...kfk..ne....sahnvtlyyykkwnintnnkpylkplfgilaknqlengnrPlvva
CSNGIGRSMAFIGTEYLARQVEADPTIELTEALKHLHEHRWNGVQTNSQL
||.|.||| .|. . ... . . .. . |... . | |.| .
csdGvGrsGtflvidsqleraktegvsdifdflrkirsqriglvdtkery
|
|||||||||
| subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 1040-1303 | 7.9e-36 | 118.7 | In-house | 32-298 (319) | alignment | ||
Range on Protein: 1040-1303
Range on HMM: 32-298/319.0
VTTIDKDHITESYAYLPEDKHRYP-TVPCKPSTAVEVIVDGKRA--PIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKN
. . ..|..... ..| ||. ... . | .||. | |... . . ..|||||.|.. | |||| | ..|. .||. . || |
lkeavndtfdsaskeenkkknryqnilaydrtrvvlseldgvegsdyinasfidgyqerekfiatqaPlentiedfWrmvWeeessivvmltklveklkv
IHNDYlpmWPRND-LQVGRFMIKMTNMDfiVQKNIMRRSFKVADSTGKFAARTLTHYQYSQWAERGVPKSHVETYELMEMVKKSE-----KPIVVHCSNG
. | ||... . ||..... . . ..... | .|. ... .|...|.|| .|.. .||.. .|.. ..|| .|||||||.|
klkky...wpeenfeeyGrlivtleeee..eledyiirklklnkkssevetRevkhfqyteWpdhdvPekatslldllkrirksrektqsgPivvhCsaG
IGRSMAFIGTEYLARQVEADPTIELTEALKHLHEHRWNGVQTNSQlYWMTLGTMYRLIKEYGFDMKIYDQQMA
.|| .|| . .|. . .... . ..| | ||...| | . .. .. . .... | ..
vGRtGtfivldamlervkeegvlDvfstvsrlRtqRnimvqrpeq.Ykfiyealleaveagdteievqdlrdr
|
|||||||||
| 0039614 | (Phosphotyrosine protein) phosphatases II | 1041-1279 | 1.6e-53 | 177.5 | In-house | 42-281 (297) | alignment | ||
Range on Protein: 1041-1279
Range on HMM: 42-281/297.0
TTIDKDhITESYAYLPEDKHRYPTVPCKPSTAVEVIVDGK----RAPIHANWVPTPGH-PHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWK
. | ..... . ||.||. ... ... | . . .. |.|..|... . ...||||| | . |.|||| |. .. |..|||. . ||...
lslkpd.ysiallpenkdknrykdilpydhsrvklkpedgvdldsdYinAsyvdgydlltrkfIatqgPlpetvedFwrmvweqgvtvivmLtklvelgr
nIHNDYLPMWPRndlQVGRFMIKMTNMDFivQKNIMRRSFKVADsTGKFaaRTLTHYQYSQWAERGVPKSHVETYELMEMVKK------SEKPIVVHCSN
.| | . |.| ..... . .....| ..| . .|. ||.||.|| | . ||| |. .|..|.|.. ...|..||||.
.kcaqywpeegg...tygdftvtllkveh..ldgytvrtlevtn.nges..rtvthfqytgwpdhgvppslellleflelvrealaelpkggpvlVHCsa
GIGRSMAFIGTEYLARQVEADPTIELTEALKHLHEHRWNGVQTNSQLYWM
|.||. .||. .. .|.| .. . ||.|.| |.|...||| ||...
GvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavqtpsqyrfl
|
|||||||||
| subfamily_PTPN13_pd | Subfamily PTPN13 | 1041-1277 | 3.6e-31 | 103.4 | In-house | 24-259 (273) | alignment | ||
Range on Protein: 1041-1277
Range on HMM: 24-259/273.0
TTIDKDHITESYAylPEDKHRYPTVpcKPSTAVEVIVDGKRAPIHANWVPTP--GHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIH
..|. ..... . .|| || | | . |..... . | |... | . ...||.| |. |..||| | . ..| |.|| ..| |
kpldtcevgkkke..nkdknryrnv..lPydetrvklgdeggyinaslikvpvgkdeyeyiacqGPlPetvkdfwqmvweqkaeviamvtlekekgkvkc
NDYLPMWPRNDLQVGR-FMIKmtNMDFIVQKNIMRRSFKVADSTGKfAARTLTHYQYSQWAERGVPKSHVETYELME---MVKKSEKPIVVHCSNGIGRS
. | | .. |.| . .. ... ... |...| || . ..| ..| .. .| . |||.| .| ... ..... ||||||| |||||
hrywPesknkklkvsnrleve..llkvqkldgfvvralavkdsesg.esrevahlnfvkwPdhgvPssaaellqfvaevrrlqtdagPivvhcsaGiGrs
MAFIGTEYLARQVEADPTIELTEALKHLHEHRWNGVQTNSQLY
..| . . .| | ....| ...| | | |||. |
Gtlitidvvlglierdkefdvkeivrklreqrqgvvqtkdqyi
|
|||||||||
| subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 1041-1281 | 1.2e-25 | 85.6 | In-house | 44-285 (319) | alignment | ||
Range on Protein: 1041-1281
Range on HMM: 44-285/319.0
TTIDKDHITESYAYLPE--DKHRYPTVPCKPSTAVEV-IVDGKR--APIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGrkveywK
. . . . ..| |.. || |. . . | . ..|. | | .| .. ..||.| | . | .||| | .|.. ||.. |
cklgvnladqtfanldqnkdknriinilafdknvvklerliGeefsdyinasfvtGyqrkdkyiaaqGPldntladfWrmiweyncstivllt......k
NIHNDYLPMwpRNDLQVGRFMIKMTNMDFIVQknIMRRSFKVADSTGKFAARTLTHYQYSQWAERGVPKSHVETYELMEMVK------KSEKPIVVHCSN
. .| | . . . .|| .|.. .. . . |...... . . | .| . . | . |||.. .. |.. |. . ...||||||
dkcsqywpl..kivikeerfkvkvdsveetae..yvvrdielsedgkekdirkitqfhflGwpdvGvpdypsdlmrlvkkvrhltskenhranivvhcsa
GIGRSMAFIGTEYLARQVEADPTIELTEALKHLHEHRWNGVQTNSQLYWMTL
|.||. ..| . | ... . ... . .. | . | . || | ...
GvGrtGvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiys
|
|||||||||
| subfamily_egg_pd | Subfamily egg | 1042-1252 | 8.4e-19 | 62.4 | In-house | 26-233 (307) | alignment | ||
Range on Protein: 1042-1252
Range on HMM: 26-233/307.0
TIDKDHITESYAYLPEDKHRYPTVPCKPSTAVEVIV-DGKR--APIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYwkNIH
..|. .|.... .| | . |.|| |. |.. . |. |||| | || .|.|. | .||| | .| ||..|||. ..| .
svdeislttaasdnnlekarskrvhckdssrvklelrrGqylddfihanrvkGkpllnefilaqaplkntvddfwrmvfqeevqyivmltsrkes..erc
NDYlpmWPRNDLQVGRF---MIKMTNMDFIVQKNIMRRSFKVADSTGKFAARTLTHYQYsQWAERGvpKSHVeTYELMEMVKKSEKPIVVHCSNGIGRSM
. | ||. . . .. ....|.. . . . | |. |. | | |.|. .. . . . . .... .... ||.||.. .|. ..
eyy...wpkaesdslvtvpGslrienlkvdskadplfrvtklklvGgddeerflehwqg.dvnnss..dvys.plrvlrklrnlskpvvvqdilGvskaa
AFIGTEYLARQVEADPT
... | .. |.
tlvaieiallsllrGpi
|
|||||||||
| subfamily_PTPRB_pd | Subfamily PTPRB | 1043-1279 | 9.8e-36 | 118.3 | In-house | 37-277 (293) | alignment | ||
Range on Protein: 1043-1279
Range on HMM: 37-277/293.0
IDKD-HITESYAYLPEDKHRYPTVPCKPSTAVEV-IVDG--KRAPIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIH
..|| .. . . ..| || . . |.. ... . | ||..| |. ||||| |. | .||| |... ... |||. . || |
vgkdqavkaaelavnraknrytnilpydhsrvkLaalkdesgsDYinanyipgynsprefiatqGPlpetvddfWrmvwekkssiivmltqlvekgkvkC
NDYlpmWPRN--DLQVGRFMIKMTNMDfiVQKNIMRRSFKVADstgKFAARTLTHYQYSQWAERGVPKSHVETYELMEMVKKS------EKPIVVHCSNG
..| ||.. . . | ..... . .... . |..|. . . |....|.. |.. |||.. .....|... ..||||||| |
eeY...WPadeepvlyGdikvtlvaee..eledwvirelkiek...ekeerkvrqyhftsWpdhgvPektktlldfvrtvreaiektaskrPivvhCsaG
IGRSMAFIGTEYLARQVEADPTIELTEALKHLHEHRWNGVQTNSQLYWM
.||. .|| . | ...| . ..... . .| |.| . |||..| ..
vGRtGtfialdrllqaieeedyvdifgivaelReeRnllvqtekqYifi
|
|||||||||
| 0050432 | (Phosphotyrosine protein) phosphatases II | 1045-1279 | 2.2e-56 | 186.8 | In-house | 57-291 (308) | alignment | ||
Range on Protein: 1045-1279
Range on HMM: 57-291/308.0
KDHITESYAYLPEDKHRYPTVPCKPSTAVEVivDGKRAPIHANWVPTP--GHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYL
.. .. ||.||. ... .. | . |.. |.|..|... ..|..|||||.| . |.|||| |.....|..|||. . ||. .. |
lleysvallpenkdkNrykdilpydhsRVkl..degsdYInAsyvdgyssklprkfIatqgPlpntvedFwrmvweqnvrvIvmLtklvengrekcaqYw
PMWPR-NDLQVGRFMIKMTNMDFivQKNIMRRSFKVADSTGKfAARTLTHYQYSQWAERGVPKSHVETYELMEMVKKS--EKPIVVHCSNGIGRSMAFIG
|. . . |..|.| ....... ......| ... .. .. ||.||..| | . ||| | . ...|.|.|| ..|||||||.|.||...||
plelgggsleygkftvtllseev..lddytvrtleltnlgdg.esrtvthfhytnWpdhgvPpspeilldflelvrkslpggpivVHCsaGvGRtGtfia
TEYLARQVEADPTIELTEALKHLHEHRWNGVQTNSQLYWM
..| .|.|.. .. . ||.|.| |.|.. ||| .|....
ldllleqlekeggvdvfeavkklReqRpgmvqtpeqylfl
|
|||||||||
| DSPc_SM00195 | 1045-1279 | 9.1e-51 | 168.1 | In-house | 16-254 (263) | alignment | |||
Range on Protein: 1045-1279
Range on HMM: 16-254/263.0
KdHITESYAYLPEDKHRYPTVPCKPSTAVEVIVDG---KRAPIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDY
| ..||. ..|.|| ... .| |.. . . |.||.. .. .....|||| | . |.|||| |... .|. |||. . .| |. ..|
k.etteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivmlteeeengkekcdry
LPMWPRNDLQVGRFMIKMTNMDFIVqKNIMRRSFKVADSTGkFAARTLTHYQYSQWAERGVPKSHVETYELMEMVKKSEK----PIVVHCSNGIGRSMAF
| . ..|.. .|... . ..| .| ... . .|..|.||| .| ..|||.|. .. ||...||||.. |||||||.|.||. .|
wpeesggketfgkisvklvevekkk.deiilrtleltkegk.eetrkvtqyqyknWpdhgvpdstksvlellravkkskstssgpivVhCsaGvgRtgtf
IGTEYLARQVEADPTIELTEALKHLHEHRWNGVQTNSQLYWM
. .... ...|.. .... | .|.| ..| . ||| |. ..
vtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfi
|
|||||||||
| PTPc_SM00194 | 1045-1279 | 9.1e-51 | 168.1 | In-house | 16-254 (263) | alignment | |||
Range on Protein: 1045-1279
Range on HMM: 16-254/263.0
KdHITESYAYLPEDKHRYPTVPCKPSTAVEVIVDG---KRAPIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDY
| ..||. ..|.|| ... .| |.. . . |.||.. .. .....|||| | . |.|||| |... .|. |||. . .| |. ..|
k.etteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivmlteeeengkekcdry
LPMWPRNDLQVGRFMIKMTNMDFIVqKNIMRRSFKVADSTGkFAARTLTHYQYSQWAERGVPKSHVETYELMEMVKKSEK----PIVVHCSNGIGRSMAF
| . ..|.. .|... . ..| .| ... . .|..|.||| .| ..|||.|. .. ||...||||.. |||||||.|.||. .|
wpeesggketfgkisvklvevekkk.deiilrtleltkegk.eetrkvtqyqyknWpdhgvpdstksvlellravkkskstssgpivVhCsaGvgRtgtf
IGTEYLARQVEADPTIELTEALKHLHEHRWNGVQTNSQLYWM
. .... ...|.. .... | .|.| ..| . ||| |. ..
vtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfi
|
|||||||||
| 0045098 | (Phosphotyrosine protein) phosphatases II | 1046-1279 | 5.8e-48 | 159.0 | In-house | 23-264 (278) | alignment | ||
Range on Protein: 1046-1279
Range on HMM: 23-264/278.0
DHITESYAYLPEDKHRYPTVPCKPSTAVEvivdgkrAPIHANWVPTPghPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPmw
. ||.. . ||.||. ... ... | |.|...... |..||||| | . |..||| |. .. ...|||. . ||. .. | |
seitpalylgnldknRykdilpydhsrVk.......dYINAsyidgy..pkkfIatqgPlpstvadfwrmlwelgitvivmltelvelgrekcaqywp..
PRNDLQVGRFMIKMTNMDFIvqKNIMRRSFKVADS---TGKFAARTLTHYQYSQWAERGVPKSH--VETYELMEMVKK-----------------SEKPI
... |. |.| ....... . ... | ..| . . |..||..| | . ||| .. ||.|.... |..|.
eggsltygdftvtllseevl..ddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllsslllldsggpv
VVHCSNGIGRSMAFIGTEYLARQVeaDPTIELTEALKHLHEHRWN-GVQTNSQLYWM
.|||| |.||. .... .. ... .... | ||.|.| ..|.. ||. .|....
lVHCsaGvgRtGtlvaaylmlell..eggvdlleavkelrsqRpglavqnleqyrfl
|
|||||||||
| subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 1046-1277 | 4e-23 | 77.1 | In-house | 36-278 (325) | alignment | ||
Range on Protein: 1046-1277
Range on HMM: 36-278/325.0
DHITESYAYLPE--DKHRYPTV-PCKPSTAVEVI--VDGKRAPIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEvEHIVMVGRKVEYWKNIHND
| |. | .|| .| |.. | . . | .| . |.. | |... . . |.|.|.| || .|.| . .... .|.| ... |.
dgiakkvamkpenkaknrfknvvaldksrvvletkkddpssdyinasylrddkkkdvflaaqaPltatindlWrlvldWr.csvvvvlneldlgkdrcav
YLPMWPRNDLQVGRFMIKMTNMDFIvqKNIMRRSFKVADSTGkFAARTLTHYQYSQWAERGVPKSHVETYELMEM-------VK---KSEKPIVVHCSNG
| | . . | . .|. .. | . . | ..| . . .|.. .|. | . ||.| .... |. |. ||.||||.|
ywpkemgksktfGglevklrtieei..sdyvhrvldvkqvkk.GetrsvkqfqlqswddmGvqkrpatlisilqlvkavservtantkastpilvhcsaG
IGRSMAFIGTEYLARQVEADPTIELTEALKHLHEHRWNGVQTNSQLY
.||. .|| .. .| . ... . .|.| ..| . |.| |
vGrtGvfislysalakvieesrvdifgfvkklrkdrpsmvetvdqyi
|
|||||||||
| subfamily_Cele-PTP-16_pd | Subfamily Cele-PTP-16 | 1047-1291 | 9.7e-10 | 32.5 | In-house | 38-278 (303) | alignment | ||
Range on Protein: 1047-1291
Range on HMM: 38-278/303.0
HITESYAYLPEDKHRYPTVPCKPSTAVEViVDgkRAPIHANWVPTPGHpHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKnIHNDYlpMWP
... || |. | | . |.. | . |||... . .. | || |.. |. ||| | .. | .... || | . |. ..|
svsknqfvknmdknrfvdvicldhskvkl.sd..ssyihasyleldss.kkailtqlplshtaadfwqmiieqkvkcvlllltdseydk.lggds..vfp
RND--LQVGRFMIKMTNMdfiVQKNIMRR-SFKV-ADSTGKFAARTLThYQYSQWAERGVPKS-----HVETYELMEMVKKS--EKPIVVHCSNGIGRSM
||. |. .|.. .. . ... ..|| . | |.. . ..| .| .| . ..| ...| .| | | ||.
rnqdflkfeersirvgef...krvelgdgwvlkvlsvsngdyksflhv.hhykawphnsipsdgspkfvkqiwqlqsvlrkysdstptvymslsgcgrag
AF--IGTEYLARQVEaDPTIELTEALKHLHEHRWNGVQTNSQLYWmtlgtMYRLIKEY
.| . | .|. . | .....| |. . . | || ||. .| |. |.
tfalfetahlslhse.qasldlvkclenvrngrlhavqnlsqfsv.....vytllaeh
|
|||||||||
| 0046845 | (Phosphotyrosine protein) phosphatases II | 1048-1279 | 1.6e-53 | 177.3 | In-house | 20-266 (284) | alignment | ||
Range on Protein: 1048-1279
Range on HMM: 20-266/284.0
ITESYAYLPEDKHRYPTVPCKPSTAVEVIVDGK----RAPIHANWVPTP-----GHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIH
.. .... .|.||. ... .. | . . .. |.|..|... ....||||| | . |.|||| |.....|..|||. . ||. .. .
lsvallpenlsknRykdilpydhsRVklksldgdledsdYinAsyvdgydldltyikkkfIatqgPlpntvedFwrmvweqnvrvIVmltelvengrekc
NDYLPMWpRNDLQVGRFMIKMTNMDFivQKNIMRRSFKVADSTGKFAARTLTHYQYSQWAERGVPKSHVETYELMEMVKKS------EKPIVVHCSNGIG
| |.. . |. |.|........ ......| ... . . ||.||..| .| ..||| | |....|... ..|||||||.|.|
aqYwple.gevltygdftvtllseev..kddytvrtleltnlgytgesrtvthfhytswpdhgvppspedlleflrlvrellenlpgggpivVHCsaGvg
RSMAFIGTEYLARQVEADP---TIELTEALKHLHEHRWNGVQTNSQLYWM
|...|| ..| .|.|.. .. . ||.|.| |.|.. ||| .|...
RtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvqtleqyrfv
|
|||||||||
| 0051299 | (Phosphotyrosine protein) phosphatases II | 1048-1279 | 1.6e-52 | 174.1 | In-house | 41-278 (288) | alignment | ||
Range on Protein: 1048-1279
Range on HMM: 41-278/288.0
ITESYAYLPEDKHRYPTVPCKPSTAVEVIVDGK---RAPIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPM
.. .. .|.||. ... .. | . | .. |.|...... ....||||| | . |.|||| |.....|..|||. . ||. .. | |.
lsaallpenleknRysdilpydhsRVkLsvldgvegsdYinAsyidgynlkrkfIatqgPlpntvedFWrmvweqnvrvIvmltklvelgrekcaqYwpl
wpRNDLQVGRFMIKMTNMDFivQKNIMRRSFKVADST---GKFAARTLTHYQYSQWAERGVPKSHVETYELMEMVKKS----EKPIVVHCSNGIGRSMAF
.. |..|.......... ..... | ..| . . |. || ||..| .| . ||| | . .....|.|. ..|.|||||.|.||...|
..ggsltygditvtllseev..lddytvrtlevtnldlldgdgesrtvthfhytnwpdhgvpdspellldflrlvrkalasgggpvvVHCsaGvgRtgtf
IGTEYLARQVEADPTIELTEALKHLHEHRWNGVQTNSQLYWM
| ..| .|.|. .... ||.|.| |.|.. ||| .|...
ialdllleqlekeggvdvleavkrlreqRpgmvqtpeqyrfv
|
|||||||||
| 0040439 | (Phosphotyrosine protein) phosphatases II | 1049-1278 | 2.7e-51 | 170.0 | In-house | 4-237 (249) | alignment | ||
Range on Protein: 1049-1278
Range on HMM: 4-237/249.0
TESYAYLPEDKHRYPTVPCKPSTAVEVIVDGKRAP---IHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMw
.... . ||.||| ... ... | . . ... . |.|...... ...|||||| | . |.|||| |. .. ...|||. . ||.... | |.
svallpenkdknrypdilpydhsrvklsilpglflsdyinAsyidgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqywpl.
pRNDLQVGRFMIKMTNMDFivQKNIMRRSFKVADStGKFAARTLTHYQYSQWAERGVPKSHVETYELMEMVKK------SEKPIVVHCSNGIGRSMAFIG
.. |..|.|........ .....| ... .. .. || .|.|| | . |||.| .. ...|.|.| ...|..||||.|.||. .||.
.ggsleygdftvtllsvev..kddytvrtleltnl.ydgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtfia
TEYLARQVEADPTIELTEALKHLHEHRWNGVQTNSQLYW
.. .|.| .. | ||.|.| ..|...||. .|...
aylmleqlekelgvdleeavkllrsqRpgavqnpeqyrf
|
|||||||||
| subfamily_Cele-PTP-11_pd | Subfamily Cele-PTP-11 | 1052-1314 | 4.3e-25 | 83.1 | In-house | 38-301 (312) | alignment | ||
Range on Protein: 1052-1314
Range on HMM: 38-301/312.0
YAYLP-EDKHRYPTVPCKPSTAVEVIVDgKRAPIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLP-MWPRND
|.| | ||| . | . | . ||||.| .| ||..||.|.. || || ... |... || . |. . |
taflkfkdlnrypniqcwdrgrftlagd.enfyihanfvkictkperfvctqgplentcthfwqlalslgstsiillcgfvedgsekcakyisdivgfvd
LQVGRFMIK---MTNMDFIVQKNIMRRSFKVA-DSTGKfaARTLTHYQYSQWAERGVPKSHVETYELMEMVKKSEKPIVVHCSNGIGRSMAFIGTEYLAR
|. | . .. . .| | .|| .||. | |||.. | . |.| | .. |. ||| ||.. ||| |.||. ... | .
ledhrvyteycteieiggkskdkithrvlkvvvkatgq..esklnhyqwaswpdhgmpdscdtalrllsavkkdkkpviahcsagvgrtgtlaliesmia
QVEADPTIELTEALKHLHEHRWNGVQTNSQlYWMTLGTMYRLIKEYGFdMKIYDQQMAMFNDVVKRLEA
. .. ... | | |.. | | ..| .. .. |. .| .|... |... ...|
alrhprkqnvkdsfvllrkdrarsvrvfpq.yvyalrcvleflyskgl.ykrneqewtkfketyakika
|
|||||||||
| subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 1053-1279 | 5.6e-36 | 119.1 | In-house | 38-268 (281) | alignment | ||
Range on Protein: 1053-1279
Range on HMM: 38-268/281.0
AYLPEDKHRYPTVPCKPSTAVEVIVDG---KRAPIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPmWPRND
| |.|| . | |.| . . | ||.||. ....||||.|. |....|| | ....|. |||| |..| | | | ....
adenvlknrYsnivaYDatrvkvtpneenkntDYinanfvpgykgekeyiatqgPvPaslvafWqmvweqkvsaivmvtreieagklkChrYWP.ddnse
LQVGRFMIKMTNMDfiVQKNIMRRSFKVADSTGKfaARTLTHYQYSQWAERGVPKSHVETYELMEMV-----KKSEKPIVVHCSNGIGRSMAFIGTEYLA
|..| ...|.|. ... ..| ||. ..|. .|.... .| .| . |||.. | | . | ||.. |.|.||| |.||. ..|. . |.
lkygdvtvkstaee..ekatyierkfkleresge..treveqlaytaWPdhGvPattkellefrkevlkltekktkaplvihCsaGvGrtGtyialDrlv
RQVEAD-PTIELTEALKHLHEHRWNGVQTNSQLYWM
..|||. ....... ...| ..| ||| | ..
kaveaeleeldvkavvaelrkernlmvqtvvqyefv
|
|||||||||
| 0037934 | (Phosphotyrosine protein) phosphatases II | 1054-1278 | 1.1e-42 | 141.7 | In-house | 8-233 (243) | alignment | ||
Range on Protein: 1054-1278
Range on HMM: 8-233/243.0
YLPEDKHRYPTVPCKPSTAVEVivDGkRAPIHANWVPTPGhphRFIATQSPINATCED----FWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPmwprND
. .|.||..... . . | . .| |.||... .. |.|||| | . |.|| || |. .. ...|||. . ||.... | | ..
penlsknrysdilpydhsrvkl..eg.sdyinanliyvtp...rliatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqywp....ge
LQVGRFMIKMTNMDFivQKNIMRRSFKVADSTGKFAARTLTHYQYSQWAERGVPKSHVETYELMEMVK------------KSEKPIVVHCSNGIGRSMAF
. |.|....... .... | ... . |. .||.| | . ||| |. ......|. .|..|..|||| |.||. ..
vtygdftvtllseeh..lddytvrtlllenldlddltrlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgRtGtl
IGTEYLARQVeadpTIELTEALKHLHEHRWN-GVQTNSQLYW
| .. ... .. | ||.|.| |.|.. .||| ||...
iaaylmllll....gvdleeavkllreqRpgkavqtpsqyrf
|
|||||||||
| 0047943 | (Phosphotyrosine protein) phosphatases II | 1055-1279 | 8.4e-54 | 178.2 | In-house | 37-264 (273) | alignment | ||
Range on Protein: 1055-1279
Range on HMM: 37-264/273.0
LPEDKHRYPTVPCKPSTAVEViVDGKRAPIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMWPRN-DLQVG
||.||. ... .. | . ||. |.|..|... ....||||| | . |.|||| |.... |..|||. . || ... . | |.. . |..|
enkdknrykdilpydhsrvkl.gdggsdyinAsyvdgynlkrkfiatqgPlpntvedfwrmvweqnvrviVmLtelvelgrekcaqYwpleggelsltyg
RFMIKMTNMDFivQKNIMRRSFKVADSTGKFaARTLTHYQYSQWAERGVPKSHVETYELMEMVKK------SEKPIVVHCSNGIGRSMAFIGTEYLARQV
.| ....... .... | ... .. . || ||..| | . ||| | . |..|.|.| |..|.|||||.|.||...|| ..| .|.
kftvtllseet..kddytvrtleltnlgtge.srtvthfhytgwpdhgvppslesllefielvrkalealpsngpvvVHCsaGvgRtgtfialdllldql
EADPTIELTEALKHLHEHRWNGVQTNSQLYWM
|. .. . ||.|.| ..|...||| .|....
ekeggvdvleavkllrsqRpgmvqtpeqyrfl
|
|||||||||
| subfamily_Cele-PTP-10_pd | Subfamily Cele-PTP-10 | 1055-1280 | 1.1e-34 | 114.5 | In-house | 54-282 (305) | alignment | ||
Range on Protein: 1055-1280
Range on HMM: 54-282/305.0
LPEDKHRYPTVPCKPSTAVEVIVDGKRAPIHANWVPTPGHPH-RFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMWPRNDL--Q
. . | || |||. .|| . ||||.| | |. |||..| |.. | ..|| | .| ||.|||. . || | .| |. . | .
iaitknryqdvpcqdqsavkldkpspsdyihanyvgcpmipekrficaqgpldqtidefwwmviqnkveqivmlcktvelgklkcaqywpaaqgeklelk
VGRFMIKMTNMDFIV-QKNIMRRSFKVADSTGKfaARTLTHYQYSQWAERGVPKSHVETYELMEMVKKSEKPIVVHCSNGIGRSMAFIGTEYLA-RQVEA
| . ... . . .| .... | .. .. | |...| .|||| .. . ||. .. |. ||||||| ||||. . . ||. . |
sgivvenvsgskpmerdaeiqitllnltysgdq..kmsvrhlqwtewpdrgvppckltslellsairgskvpivvhcsagigrtgtivaieyilekiaen
DPTIELTEALKHLHEHRWNGVQTNSQLYWMT
| . | .| | ..| .|.. | ..
kpcppmpelvkalrdqrafsiqndvqylfih
|
|||||||||
| 0042113 | (Phosphotyrosine protein) phosphatases II | 1056-1279 | 9.5e-50 | 164.6 | In-house | 9-235 (245) | alignment | ||
Range on Protein: 1056-1279
Range on HMM: 9-235/245.0
PEDKHRYPTVPCKPSTAVEVIVDGKRA---PIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMwpRNDLQV
||.||. ... ..| | . .|| . .|.|..|... ....||||| | . |.|||| |. .. ...|||. . .|.... | |. .. |..
nkdknrysdilpydhtrvklspdggdldsdyinasyvdgyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywpl..geslty
GRFMIKMTNMDFivQKNIMRRSFKVADsTGKFAARTLTHYQYSQWAERGVPKSHVETYELMEMVKK-----SEKPIVVHCSNGIGRSMAFIGTEYLARQV
|.|........ .....| ..| . .|.. |. .||.| | . ||| .. ...|.|.| |..|..|||| |.||...||. ....|.
gdftvtllseeh..lddytvrtlevtn.lgddesrevihyhylpwpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylmleql
EADPTIELTEALKHLHEHRWNGVQTNSQLYWM
|. .. | ||.|.| ..|.. ||| ||....
ekelgvsleeavkelrsqRpgavqtpsqyrfl
|
|||||||||
| subfamily_Cele-PTP-6_pd | Subfamily Cele-PTP-6 | 1056-1279 | 1.6e-35 | 117.6 | In-house | 41-269 (307) | alignment | ||
Range on Protein: 1056-1279
Range on HMM: 41-269/307.0
PEDKHRYPTVPCKPSTAVEVIVDGKRA-PIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMWPRNDLQVGR
|| || |.|. . . | .|| . ||||.. . .|..||..| | ..| .||||..| .|| ..|. . .| | ..| |. . | |
ntdknryqdvkcqdkgrivvkfdglasdyihanylgiaikpkkficaqgplentqysfwamaiqekvesvimlckvielakikceqywpleegqklvfge
FMIKMTNMDFIVQKNIM-RRSFKVADSTGKF--AARTLTHYQYSQWAERGVPKSHVETYELMEMVKKSEKPIVVHCSNGIGRSMAFIGTEYLAR-QVEAD
.. .. ..| .|.. .. .||..|.|...| .||||. . . .|.| |. . |.||||| |.||| . .. .. ..
apntisvanlgakklapdedlinvttlkvdwaqksrtiqhlqwenwpdrgvpqinltainlleavrydtnpvvvhcsaGvGrsGtivaislvqdkmiaGi
PTIELTEALKHLHEHRWNGVQTNSQLYWM
.. . .. | ..| .||. | ..
nckdmkklveelrsqrhyaiqteaqylyl
|
|||||||||
| subfamily_PTPN6_pd | Subfamily PTPN6 | 1056-1278 | 2.1e-25 | 84.3 | In-house | 96-288 (306) | alignment | ||
Range on Protein: 1056-1278
Range on HMM: 96-288/306.0
PedkhryptvpckpstavevivdgkrapihanwvptpghPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMWPRNDLqVGRf
...|||| ...| .||| | .| . . |||. ..|| |. | | ... |.
s......................................dksyiatqgclettvsdFWrmvwqensrvivmttkevErgkekCarYWPdeeekee.yGk.
mIKMTNMDFIVQKNIMRRSFKVADSTGKFAARTLTHYQYSQWAERGVPKSHVETYELMEMVKKS--------EKPIVVHCSNGIGRSMAFIGTEYLARQV
|..||.. ... . |...|. . | .|.. .|.. .| . ||||. ...| |.. . |||||||.|||| .|| .. | ...
.isvtnvseksladYilRelsvskkkkkkeerevfqyhfksWPdhgvpkdpgavLdfledvnrkqeeleeaeagpivvhCsaGiGRtGtfiviDillkli
E---ADPTIELTEALKHLHEHRWNGVQTNSQLYW
| | |.. .. | ..|.| |||..| .
ekkgldadidiqklvksvreqrsglvqteqqykf
|
|||||||||
| subfamily_Cele-PTP-13_pd | Subfamily Cele-PTP-13 | 1056-1275 | 6.8e-21 | 69.2 | In-house | 37-257 (281) | alignment | ||
Range on Protein: 1056-1275
Range on HMM: 37-257/281.0
PEDKHRYPTVPCKPSTAVEVIV--DG--KRAPIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMWPRNDLQ
. | || .|| . |.. | ||||.. .| . .| || | . | ||| | | . |||. . .| .. .|.| . ||
nnkknrylnipcldisrvqlkvkmpnknstdyihanyirspflkrgyiltqgpkketradfwrmiwqenttaivmlcqfletnrekcaeyfprnahcclq
VGRFMIKMtnMDFIVQKNIMRRSFKVADStGkfAARTLTHYQYSQWAERGVPKSHVETYELMEMVKKSEKPIVVHCSNGIGRSMAFIGTEYLARQVEADP
. .. .. | |.| .. .... | .| .||. . .| . ||.| ... .. | |.||| |.||| ... | . . .
fdklsvsy..edstvnkslvttrlnlsye.g..etrlithwlwkewpdwqvpessevmlkilrkirarstppvihcsagvgrsgtlmaveialqsihshf
TI-ELTEALKHLHE-HRWNGVQTNSQ
|. .. . . ||. | ||| |
tlpdikqivshlrvtgraasvqtlqq
|
|||||||||
| subfamily_PTPN9_pd | Subfamily PTPN9 | 1057-1278 | 3.4e-30 | 100.1 | In-house | 43-281 (297) | alignment | ||
Range on Protein: 1057-1278
Range on HMM: 43-281/297.0
EDKHRYPTVPCKPSTAVEVI-VDGKR--APIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYlpmWPRNDLQVG
| || | | .| | . ||.. |.||.| ... ||||| |.. |..||| | . || |||. | || . . | || .. ..
leknrytdvlcydetrvvlakvdedeasdyinanfvdGykqkkafiatqGplkktvsdfWrmvWeqevlvivmttrvvergrlkcgqy...Wpleeessa
RF-MIKMTNMDFIVQKNIMRRSFKVADSTGKfAARTLTHYQYSQWAERGVPKSHVETYELMEMVKK-----------------SEKPIVVHCSNGIGRSM
.| ....|.. .... . |.... ... . |..||.|. | . |||.| . ...|.|.. |. ||||||| ||||.
efgdlsvsnveveeeedykvrvleiknvkte.esrkvthfqflsWPdyGvPssaaslldvlekvrekqalavkelgdewkghpsgPPivvhcsaGiGrtG
AFIGTEYLARQVEADPTIELTEALKHLHEHRWNGVQTNSQLYW
.|| .. ..| |....|..|.| . | .||. | ..
tfitldiclsrleevgtvdvvetvkllrtqrafsiqtpeqyef
|
|||||||||
| subfamily_PTPN5_RR_pd | Subfamily PTPN5_RR | 1057-1277 | 1e-27 | 92.0 | In-house | 29-258 (274) | alignment | ||
Range on Protein: 1057-1277
Range on HMM: 29-258/274.0
EDKHRYPTVPCKPSTAVEVIVDGKRAP----IHANWVPTPGH-PHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMWPRNDLQ
. | || |. . . | . . ... | ||.. ... . ..||| |. | .||| | | ||. |||. . | .. . | | ...
qtknryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntvadfWrmiyqeevqvivmltklkeaneqkCavyfPdaedyeis
VGRFMIKMTNMDFIVQKNIMRRSFKVADSTGkfaARTLTHYQYSQWAERGVPKSHVETYELMEMVKKSE-------KPIVVHCSNGIGRSMAFIGTEYLA
..... . . ... |.. . .. |...|| |..| .. .|.. . .|.. |..|. |.||||| |||| .||...
erygdveikvekiverndysvrklvlkyler...ersvkhywytdWPdhksPddantlldlvleveesreeenaklapvvvhCsaGiGrtGcfiaisiav
RQVEADPTIELTEALKHLHEHRWNGVQTNSQLY
||.... .... . .| .| |||..|
rqlreeivvdvlkivcnlrldrGGmvqtseqye
|
|||||||||
| subfamily_Cele-PTP-15_pd | Subfamily Cele-PTP-15 | 1057-1290 | 7.3e-26 | 85.8 | In-house | 36-273 (285) | alignment | ||
Range on Protein: 1057-1290
Range on HMM: 36-273/285.0
EDKHRYPTVPCKPSTAVeVIVDGKRAPIHANWVPTPGHPH-RFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMWPRNDLQVGRF
| || | | | | |. . | |||.|. ||. . .|.|| |. | ||| | | .. ...|. .| . | | . ...|..
pdlnryadvrcieetrv.vlknhdrdyihaswmrmpgkdqstyittqgplpetlsdfwhmiyqekiayvlmlctlfeggvekcalyypeklgevvkfgky
MIKMTNMDFIVQKNIMRRSFKVADSTGK-FAARTLTHYQYSQWAERGVPKSH---VETYELMEMVKKSEKPIVVHCSNGIGRSMAFIGTEYLARQVEADP
| .|. . .. | .. . | | | .. |. .| |. .. |. ||||.|||| |.||. .|.| .| . .. .|
eitlteckeeaiagtilnaltvintedasseplymnhvqvpwwpdqlapedarpmielykwvkkvnpkekpicvhcsagvgrtatfvgidyatirimenp
TIELTEALKHLHEHRWNGVQTNSQLYWMTLGTMYRLIKE
||. . .. .. |.. ||. |. .. . | .| |
niemldivremramrfqavqshmqflflyvvlmeyfige
|
|||||||||
| subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 1057-1278 | 2.8e-23 | 77.1 | In-house | 39-268 (287) | alignment | ||
Range on Protein: 1057-1278
Range on HMM: 39-268/287.0
EDKHRYPTVPCKPSTAVEVIVDGKR--APIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMWpRNDLQVGR
| || | | | . .|. . | ||.|.. . ..|||.|.|| || ||| . .. .. .... |.|| .. | | . ..||
vkknryadvlPiddtrvllsaegelGsdyinanyvasytddeafiaaqgPiaatvrdfwravletrsasvitmtreveearlkcykywPer.evPmrvGG
FMIKMTNMDFIvQKNIMRRSFKVADSTGKfAARTLTHYQYSQWAERGVPKSHVETY-------ELMEMVKKSE--KPIVVHCSNGIGRSMAFIGTEYLAR
. . . . | . . |.....| .. || . ... .| ..... . | . .|. .... |.|||.. ||||| .. | | .
ysvvlldydik.ePeygvralrlidletr.earvvkqldllswPdkvlaPtavglirfvldvkqhielardasevGPlvvhddvGiGrsGillatlvlvs
QVEADPTIELTEALKHLHEHRWNGVQTNSQLYW
. | .. . .. .| |.| ||. ||
rledlGrvdvaavvirlreyraalvqavvqlrl
|
|||||||||
| 0036941 | (Phosphotyrosine protein) phosphatases II | 1058-1306 | 3.7e-62 | 205.6 | In-house | 41-295 (297) | alignment | ||
Range on Protein: 1058-1306
Range on HMM: 41-295/297.0
DKHRYPTVPCKPSTAVEViVDGKRAPIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMWPRNDLQVGRFMI
.|.||. ... ..| | . |.. |.|..|........||||| | . |.|||| |.... |..|||. . ||.... | |.. .. |..|.|..
eknRykdilpydhtRVkl.ddegsdYinAsyvdgydlkrkfIatqgPlpntvedFWrmvweqnvtvIvmltelvelgrekcaqywpleegesltygdftv
KMTNMDFIVQKNIMRRSFKVADStGKFAARTLTHYQYSQWAERGVPKSHVETYELMEMVKK------SEKPIVVHCSNGIGRSMAFIGTEYLARQVE---
...... . ... .| ..| | |. ||.||..| | . ||| |. . ...|.|.| |..|..||||.|.|||..||. ... .|.|
tllsvevvllddytlrtlevtdt.gngesrtvthfhytgwpdhgvpespaslldfielvrkvlkllpsggpvlVHCsaGvgRsgtfiaadlmlqqledkl
ADPTIELTEALKHLHEHRWNGVQTNSQLYWMtLGTMYRLIKEYGFDMKIYDQQMAMFN
... . ||.|.| |.|.. ||| .|.... ... |.| . ... .... .....
keggvdileavkklReqRpgavqtleqyrfl.yeallellkkkltkepllklvlllls
|
|||||||||
| Y_phosphatase | Protein-tyrosine phosphatase | 1058-1279 | 1.7e-51 | 170.3 | Pfam-A | 3-229 (235) | alignment | ||
Range on Protein: 1058-1279
Range on HMM: 3-229/235.0
DKHRYPTVPCKPSTAVEV-IVDGKRAPIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMWPRNDLQVGRFM
.|.||..... .| |.. .|. |.||.| . ....||||| |.. |.||||.|..|..|. |||. . .| .. ..| | .. |. |..
kknRykdilpydktrvklkgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeesltygdik
IKMTNMDFIVQKNIMRRSFKVADSTGKFAARTLTHYQYSQWAERGVPKSHVETYELMEMVKKSE----KPIVVHCSNGIGRSMAFIGTEYLARQVEADPT
..... .|... | ... ..... . |......| .| ..|||.| . .|...|.||. .|.|||||.|.||.. |. ..| .|.||. .
velkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldilleqleaeee
IELTEALKHLHEHRWNGVQTNSQLYWM
... ...|.| ..| . ||. .|....
vdvlqivkelRkqRpgmvqsleqYifl
|
|||||||||
| Y_phosphatase | Protein-tyrosine phosphatase | 1058-1279 | 1.7e-51 | 170.3 | In-house | 3-229 (235) | alignment | ||
Range on Protein: 1058-1279
Range on HMM: 3-229/235.0
DKHRYPTVPCKPSTAVEV-IVDGKRAPIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMWPRNDLQVGRFM
.|.||..... .| |.. .|. |.||.| . ....||||| |.. |.||||.|..|..|. |||. . .| .. ..| | .. |. |..
kknRykdilpydktrvklkgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeesltygdik
IKMTNMDFIVQKNIMRRSFKVADSTGKFAARTLTHYQYSQWAERGVPKSHVETYELMEMVKKSE----KPIVVHCSNGIGRSMAFIGTEYLARQVEADPT
..... .|... | ... ..... . |......| .| ..|||.| . .|...|.||. .|.|||||.|.||.. |. ..| .|.||. .
velkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldilleqleaeee
IELTEALKHLHEHRWNGVQTNSQLYWM
... ...|.| ..| . ||. .|....
vdvlqivkelRkqRpgmvqsleqYifl
|
|||||||||
| subfamily_Cele-PTP-18_pd | Subfamily Cele-PTP-18 | 1058-1280 | 7.2e-39 | 128.3 | In-house | 50-280 (305) | alignment | ||
Range on Protein: 1058-1280
Range on HMM: 50-280/305.0
DKHRYPTVPCKPSTAVEVIVDGKRAPIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMWPRNDLQVG----
.| || | | | . ||||.| || |.||| ||.|.. || ||| ||.| || | |. .| . .|.. .. |.
gknrykdvgcldnnrvklegpwpheyihanyvstptnpkrfictqaplektcadfwymclqdkveaifmlcnllekgakkcleyfaskdkdvlefeekgq
RFMIKMT---NMDFIVQKN-IMRRSFKVADSTGKfAARTLTHYQYSQWAERGVPKSHVETYELMEMVKKSEKPIVVHCSNGIGRSMAFIGTEYLARQVEA
. ..|. ...| . . .... | . .|. || ||| . .| .|||| . . ||.| . | ||||||| ||||. . . ||. |. |
kisvkfessvtlkfrkdakakvtetvlviegpge.karkvthyhwidwpdrgvpaadlailellekarpskgpivvhcsagigrtgsvvmleyildqlla
DPTIELTEA-LKHLHEHRWNGVQTNSQLYWMT
|| |. |... | | | .||. | ..
gqiiedtdkilqkireqrnnsiqtdaqylfvh
|
|||||||||
| subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 1058-1279 | 1.7e-35 | 117.4 | In-house | 49-271 (288) | alignment | ||
Range on Protein: 1058-1279
Range on HMM: 49-271/288.0
DKHRYPTVPCKPSTAVEVIV---DGKRAPIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYlpmWPRNDL--QV
.| ||. . ..|.. . | |... .. ...||||.|. .| .||| . ..... |||. || |. ..| || .| .
kknRyrnilpyDekrvklkkleeeagaDYinasyidgekkkkkyiatqgPladtvndfWelvyenktstivmltelveggktkCeeY...WPdadkpkny
GRFMIKMTNMDfiVQKNIMRRSFKVAdstGKFAARTLTHYQYSQWAERGVPKSHVETYELMEMVKKS---E-KPIVVHCSNGIGRSMAFIGTEYLARQVE
| . ..... ..... |.. . | ...|.||| |.. |||.|. . ||...|| . . .||.||||.|.||. || . | .||
Gsvtvtlvesk..eledfvlrkllle...kkkteleitqyqylaWpdhgvPeskapllellrqvkvanqadtgpiivhCsaGvGrtgtFialdalidave
ADPTIELTEALKHLHEHRWNGVQTNSQLYWM
.. .|........| ..| . ||| .| ..
eedyiDvagtvaklRkqRallvqtlkqYefi
|
|||||||||
| subfamily_PTPN3_pd | Subfamily PTPN3 | 1058-1278 | 4.1e-33 | 109.5 | In-house | 43-266 (280) | alignment | ||
Range on Protein: 1058-1278
Range on HMM: 43-266/280.0
DKHRYPTVPCKPSTAVEViVDGKRAPIHANWV----PTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMwPRNDLQVG
.| || . .| |.. .... | ||.| |. | |.|||| |.. |..||| | . ... |||. || . | | . . |. |
sknryrdilpydatrvkl.kesetdyinanyvnmeipstglvnryiatqGPlaktatdfWqmvweqksslivmlttlverGrvkChqyWPe.tedeleyg
RFMIKMTNMDfiVQKNIMRRSFKVADSTGKfAARTLTHYQYSQWAERGVPKSHVETYELMEMVKKS----EKPIVVHCSNGIGRSMAFIGTEYLARQVEA
.|..|... | .|... | . . |.. | |.... || .|.. |||... . |..| |.| |.|.||||| ||||. .| | .||
efsvkceked..etksyvlrelvlkdketk.eerkilqlqylaWpdhgvPddsadflefvervrklrsgkeePvvvhCsaGigrtGvlilletalaliea
DPTIELTEALKHLHEHRWNGVQTNSQLYW
. . .... . | . |||.|| .
aepvypldivrtmrdqramlvqtasqykf
|
|||||||||
| 0041856 | (Phosphotyrosine protein) phosphatases II | 1058-1281 | 7.4e-33 | 109.0 | In-house | 3-165 (182) | alignment | ||
Range on Protein: 1058-1281
Range on HMM: 3-165/182.0
DKHRYPTVPCKPSTAvevivdgKRAPIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGrKVEYWKnihndylpmwprndlqvgrfmi
||.||. ... . . |.||.. . .. |||||| | . |..||. | .. . .||.. . ||
dknrysdilpydhsr.......dldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlt.eelywp......................
kmtnmdfivqknimrrsfkvadstgKFAARTLTHYQYSQWAERGVPKsHVETYELMEMVKKSEKPIVVHCSNGIGRSMAFIGTEYLARQveadpTIELTE
.. |. ..|.| .| ||| |.....|.|.....|..|||| |.||. .... .. .. . |.|
.........................ellerlgiqylylpwpDhgvpd.ldelldfieevleeggpvlVHCsaGvgRtgtlvaaylmkkl.....gvslee
ALKHLHEHRWNGVQTNSQLYWMTL
|.|.. ..|...|.| .|... |
avklvrsrRpgmvitpnqyfflql
|
|||||||||
| subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 1058-1296 | 3.9e-31 | 102.8 | In-house | 58-287 (290) | alignment | ||
Range on Protein: 1058-1296
Range on HMM: 58-287/290.0
DKHRYPTVPCKPSTAVeVIVDGK-RAPIHANWVPtpGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMWPRNDLQVGRFM
| || |.| | | .. || .|||.| | || || ....| |.| | .| .| |||. .| | ..| | . | | .
kknrykdvvcndktrv.ilkdGydGdyvhanyvk..GlkamfiltqGalkdtvidiwrmvlqekvaaivmlceliedGkakceqyypekeGevltfGeit
IKMTNMDfIVQKNIMRRSFKVADST-GKfaARTLTHYQYSQWAERGVPKSHVETYELMEMVKKSEKPIVVHCSNGIGRSMAFIGTEYLARQVEADPTIEL
. .. | ..||... . | | || | |.. | .. |..| . .. ...| |.||||| ||||. .|. | .. . ..|
vlcseed.dkdaniikktlsvrdkdsGk..ehklkhlkikswpdksvalstlallrtlrilrkasGpvvvhcsaGiGrtGtfvaievglqilldGkeldl
TEALKHLHEHRWNGVQTNSQlYWMTLgtmyRLIKEYGFDMK
. . | . | | || . | | . . ... ..| |.|
ldlvralrnsrlnsvqvdiq.ylalv....eilldlGkdfk
|
|||||||||
| subfamily_Cele-PTP-14_pd | Subfamily Cele-PTP-14 | 1058-1279 | 9.3e-18 | 58.8 | In-house | 54-282 (310) | alignment | ||
Range on Protein: 1058-1279
Range on HMM: 54-282/310.0
DKHRYPTVPCKPSTAVEVIVDGKRA--PIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYlpmWPRNDLQVGRF
| || | |. .. | . .| | ||||.| | || .| |.. | ||| | .| | |... . .| . | || .
hknrysdvvcldtsrvklkidksryedyihanyvktnylrstficsqgplqhtiidfwrmifqeraesilllckvgeegrpkcvgy...wpslgvtetyg
MIKMTNMDFIVQK--------NIMRRSFKVADSTGKFAARTLTHYQYSQWAERGVPKSHVETYELMEMVKKSEKPIVVHCSNGIGRSMAFIGTEYLARQV
|..||. .. .. | . .. .. .. .| .|||| .. | . . | ||||| |..| . . .. ..
cirvtnlsesseefeicnlavtfvpdnvpvdeqpanlkelrvslikwpnwpdrgvpdekchtvpqrllaqvrhgpcvvhcsagkdrlyvvvalklkidkl
EADPTIELTEALKHLHEHRWNGVQTNSQLYWM
. ... | .|. .| .||. | ..
drglkvdaeevktellksraiciqtelqylii
|
|||||||||
| subfamily_Cele-PTP-8_pd | Subfamily Cele-PTP-8 | 1059-1291 | 2.9e-32 | 106.9 | In-house | 46-276 (288) | alignment | ||
Range on Protein: 1059-1291
Range on HMM: 46-276/288.0
KHRYPTVPCKPSTAVEVIvDGKRAPIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMWPRNDLQVGRFMIK
. || .|. | | . | |.|| |.. ...|.| .|.|.|.| | .| | .. .||.|||. . .| |. ..|.|. . ..||.
rdryenlprcditrvkls.ddpdfyiaanvvssakykrrlicaqaPlngtieelWkmllesdveyivmlcellekGkeksaeyfPsklGekarigrlctv
MTNMDFIVQKNIMRRSFKVADSTGKFAarTLTHYQYSQWAERGVPKSHVETYELMEMVKKSEKPIVVHCSNGIGRSMAFIGTEYLARQVEADPTIELTEA
. . ..| . ... . . . . . .| . |||.... |.|..|. .||||||.|.|.||....| . .... | . . .
vkkkradidklvkvsllriskegeekv..ivkilhlleWdddgvPenylsplrllevlkslqkPivvhssaGvGrtgtlililialeslrlddflgirsl
LKHLHEHRWNGVQTNSQ-LYWMTLGTMYRLIKEY
|..| |.| . .||. | || . . |.| |
laklreerfkaiqtemqylyvhrcvleelllkky
|
|||||||||
| subfamily_PTPN1_pd | Subfamily PTPN1 | 1059-1279 | 8.7e-26 | 85.3 | In-house | 35-263 (290) | alignment | ||
Range on Protein: 1059-1279
Range on HMM: 35-263/290.0
KHRYPTVPCKPSTAVEvIVDGKRAPIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMWPR-NDLQVGRFMI
. || | . .. . ... | |. | . ...| || |. |.. || | . . .||. . || .. .| |. . . |.. .
lnryrdvspydhsrik.leradndyinaslveleeakrsyiltqGPlpntvdhfWqmvWeqkskavvmlnkvvekeqikcaqywPqgeeekellledtkl
KMTNMDFIVQKNIMRRSFKVADSTGKfAARTLTHYQYSQWAERGVPKSHVETYELMEMVKKS------EKPIVVHCSNGIGRSMAFIGTEYLARQVEADP
|.. . .... ..| ... . . . .|...|. | .|.. |||.| ... |..| | |.||| ||||| .|. . . ..|.
kvkliseerksyytvrllelenlktq.etreilhfhyttwpdfgvpespaaflkflfkvresGslssdvGpavihcsaGiGrsGtfclvdtclvliekkd
T---IELTEALKHLHEHRWNGVQTNSQLYWM
... . | .| ..| .|| || .
dlssvdikkvllelrkyrlGliqtadqlrfs
|
|||||||||
| subfamily_Urchin-PTP-4_pd | Subfamily Urchin-PTP-4 | 1059-1278 | 5.8e-16 | 52.9 | In-house | 48-227 (392) | alignment | ||
Range on Protein: 1059-1278
Range on HMM: 48-227/392.0
KHRYPTVPCKPSTA--VEVIVDG-KRAPIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWknihndylpmwprndlqvgrf
| || . |. .||| | .. . | ..|. . .||.|.| |. .||| | .| .| |.|| . |
knryknilpydsarvkleviddipdsdylnasyipsfdnekayiasqgpnaaslddfwrmvfqenvttiamvtklkegd.....................
mikmtnmdfivqknimrrsfkvadsTGKfAARTLTHYQYSQWAERGVPKSHVETYELMEMVKKS----EKPIVVHCSNGIGRSMAFIGTEYLARQVEADP
|. ||| . .....| ...||| .... || .|...||| |.||. | . . . .
.........................kgd.dartvaqfhftewPdkdvpkhtssllkfikevkadfGqythpliihcsagvgrtgvvisidsvvahakktr
TIELTEALKHLHEHRWNGVQTNSQLYW
... . . ....| |||. | .
mvdvfnfvtnirrkrpymvqtkeqyaf
|
|||||||||
| subfamily_CG42327_pd | Subfamily CG42327 | 1060-1208 | 2.2e-08 | 28.1 | In-house | 32-182 (319) | alignment | ||
Range on Protein: 1060-1208
Range on HMM: 32-182/319.0
HRYPT-VPCKPST--AVEVIVDGKRAPIHANWVPTPGHP-HRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMWPRNDLQVGRF
|. || .. .. | | ..|..| . .||.| . . . ||| . . || . | . .||| | .
srvinvvPlPetrvvlqrigdddkdeyldasyvrGyddapnsyiaaqvsledsssdfwrtvweqqsrvivqltdlselGikvcaeylPtketldntslyG
MIKMTNMDFIVQKNiMRRSFKVADSTGKFAARTLTHYQYsQWAERGVPKSHVE
|..| . |... | . | .| |||| | .| | .|| ..
dilvtlkgrevkdr.yaistlllkrvdkeesrelthywy.kwleaevPaeeaa
|
|||||||||
| subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 1061-1279 | 2.4e-30 | 100.4 | In-house | 25-256 (270) | alignment | ||
Range on Protein: 1061-1279
Range on HMM: 25-256/270.0
RYPTVPCKPSTAVEV---IVDGKRAPIHANWVP-TPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMWPRNDLQVGRFM
|| . .| | | . | . | | ||.|. |.....||...| ..| ..|| | .. .|. |||. .| .. . | | | . ... .
RyadiLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpaepkekvkledgk
IKMTNMDFIVQKNIMRRSFKVAdSTGKfaARTLTHYQYSQWAERGVPKSHV---ETYELMEMVKKS-------E--KPIVVHCSNGIGRSMAFIGTEYLA
||.... .. ... .. ..|. | |.|..| .| ..|||... .| .|..|... . .|..||||.|.||. .| ...
ikvlalseekeegyiltrlrle.ekge..errlvHfwyntWpdhgvpreedsslstdqllkmlravrrsekeldkaePllvHcsaGvgRtGtlialDiav
RQVEADPTIELTEALKHLHEHRWNGVQTNSQLYWM
| .| . ..... ...| ..| . ||. | ..
rlLeetkkvdvlaiieelRkdRmalvqhpeqyefl
|
|||||||||
| subfamily_PTPRK_pd | Subfamily PTPRK | 1077-1277 | 7.9e-31 | 102.0 | In-house | 65-267 (314) | alignment | ||
Range on Protein: 1077-1277
Range on HMM: 65-267/314.0
VDGK--RAPIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYlpmWPRNDLQVGRFMIKMTNMDfiVQKNIMRRS
.|| | |... . .|. ||.|| |.. | .||| . ... |||. || . | || . . | . ... ... ...... |
idgdpssdyinaalidsykrpaafivtqgPlqetvkdfWrlvydencasivmltelvevgrvkClky...WPedtevygdikvelvete..llaelvvri
FKVAD-STGKFAARTLTHYQYSQWAERGVPKSHVETYELMEMVKKSE----KPIVVHCSNGIGRSMAFIGTEYLARQVEADPTIELTEALKHLHEHRWNG
|.| . |. . |.. ..|. .|.. .||.| .|. ||||. .||||||.| ||. .|| . . .| . .... .| | | ... |
frveklargqeeirevrqfqflgWpdhdvPvsatgllklvrrvkksqeeeaGrivvhCsaGaGrtGtfiaidivldmieregvvdvfnavktlrsrkvnm
VQTNSQLY
|.|. |
veteeqyk
|
|||||||||
| subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 1078-1276 | 1.1e-27 | 91.8 | In-house | 74-268 (315) | alignment | ||
Range on Protein: 1078-1276
Range on HMM: 74-268/315.0
DGKRAPIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYlpmWPRNDLQVGRFMIkmTNMDFIVQKNIMRRSFkv
| . . ||... ...|.||.|.| |. .||| . ..... .|||. || |. . | || ... |.. . | .. |.... |..
dphsdyvnanfidGynkkrryiaaqgpnvasvkdfwrlvfeedigkivmltnlvegekrkaeky...wpdkkviyGkitv..trkseevnteytvrtl..
aDSTGKFAARTLTHYQYSQWAERGVPKSHVETYELMEMVKK----SEKPIVVHCSNGIGRSMAFIGTEYLARQVEADPTIELTEALKHLHEHRWNGVQTN
. . |.. ..|. | . ||||. . .|. ||. | .||||||.|.||. .|| . . |.||. |.. .... . . | . ||.
.svvfgdnirevvqlhytswpdmgvpkytiplmnlirtvkqhhtnsvgaivvhcsaGvGrtGtfitldavldqaeaenaidvynfitgvrqnrikmvqva
SQL
|
eqy
|
|||||||||
| subfamily_PTPRG_pd | Subfamily PTPRG | 1078-1279 | 4.5e-27 | 89.5 | In-house | 70-279 (563) | alignment | ||
Range on Protein: 1078-1279
Range on HMM: 70-279/563.0
DG---KRAPIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMwpRNDLQVGRFMIKMTNMDFIVQK---NIM
| | | ||.. . . ||||| |.. |..||| | . .|. |||. || .. . | | . ...| . ..... . .. ...
pgkkkklDYinAnyidGyqkskafiatqgplkdtfddFWrmiWeqnvaiivmitnlvergrrkcdvYWPk..desetygalqvtlieeevlalytvrtlv
RRSFKVADSTGKFAARTLTHYQYSQWAERGVPKSHVetYELMEMVKKSE------KPIVVHCSNGIGRSMAFIGTEYLARQVEADPTIELTEALKHLHEH
. .|. . . .. ..|.|..| . |||.. . ..|. ..|.| |||||||.|.||. .| . | .|.... .... . |||.. .
iknlklkkkkqcdteklvrqyhytkWPdhgvPehsl..pvLifvkkssaankaeaGPivvHcsaGvgrtGtyivldtllkqiqqenavnvfgflkhiraq
RWNGVQTNSQLYWM
| . |||. | ...
RnflvqteEqYifl
|
|||||||||
| subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 1079-1204 | 1.4e-12 | 42.1 | In-house | 57-181 (297) | alignment | ||
Range on Protein: 1079-1204
Range on HMM: 57-181/297.0
GKRAPIHANWVPTPG--HPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMWPRNDLQVGRFMIKMTNMDFI-VQKNIMrRSF
.| | |..| | .. ..| .| |..|| .||| . .. .| |||| . | .. | | . |. | .... .. |. .
terdyinadyvvfpdeeadlkyilaqGplsatvddfwtlvaeqdvrvivmvaklqedGrdkcapywpsvvqerlkagdvvveflsstsdefdrvil.tel
KVADStgkFAARTLTHYQYSQWAERGVPK
.. | ..| |. | . |||
qliyr...sesrvvrhvqflswpdhGvps
|
|||||||||
| subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 1080-1276 | 3.1e-33 | 110.2 | In-house | 73-272 (305) | alignment | ||
Range on Protein: 1080-1276
Range on HMM: 73-272/305.0
KRAPIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMWPRNDLQVGRFMIKMTNMDfiVQKNIMRRSFKVAD
.. | |..| . . ...|..|.|.. | .||| . ... |..|||. . || |. . | | ... . |.|...... .. . | .|..
dsdyinasyvdgykrkkkyivaqgPlkntvadfWrliveekvstivmltklveggkdkCrqYWpesktekkefgefsvelksek..tasdyieRklkisi
STGKFAARTLTHYQYSQWAERGVPKSHVETYELMEMVKK----S-EKPIVVHCSNGIGRSMAFIGTEYLARQVEADPTIELTEALKHLHEHRWNGVQTNS
.. ||...|| .| . |||.. .|.. |.| . ..|..||||.|.||. .|| . ..... .... | ||.| ..| . |||
ededkesrtvlqyqltdWPdhGvpqfatsllslikrvqkdqkkdkgvpllVhCsagvgRtGvfiavdialerlkkEevvdvfevlkqlRskrmkmvqtld
QL
|
qY
|
|||||||||
| subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 1080-1277 | 8e-26 | 85.6 | In-house | 71-267 (315) | alignment | ||
Range on Protein: 1080-1277
Range on HMM: 71-267/315.0
KRAPIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMWPRNDLQVGRfmIKMTNMDFIVQKNIMRRSFKVAD
.. | | ... . . .||.| | .|. .||| | .|..| |||| | | | . | | . . | ||.. .. . . . | . . .
dsdyinasyiksvdddkayiasqgPlkasvddfwrmvlqekvttivmvtkkqegdkikcrqywPdrkadsvefGs..ikvellsleadtdgvarklvtrk
STgkfAARTLTHYQYSQWAERGVPKSHVETYELMEMVKKS----EKPIVVHCSNGIGRSMAFIGTEYLARQVEADPTIELTEALKHLHEHRWNGVQTNSQ
| . ||.| .|. .| ..||.| .|. || . | ...|||| |.||. .| . |.. .... . .| | ..| |||. .
se...esrtvtqfqftewPdkGvdkqtssllklikevkadngkkefsllvhcsaGvGrtGvvisidevvaqikrtrsvdvfnfvknlrakrpylvqteee
LY
ya
|
|||||||||
| 0044763 | (Phosphotyrosine protein) phosphatases II | 1081-1280 | 4.5e-20 | 67.5 | In-house | 18-164 (178) | alignment | ||
Range on Protein: 1081-1280
Range on HMM: 18-164/178.0
RAPIHANWVPtpghPHRFIATQSPinatcEDFWAMCMQYEVEHIVMVGRKVEYWkniHNDYLPMWP---Rndlqvgrfmikmtnmdfivqknimrrsfkv
.|.|... |. ..... | .|.... .. . |||.. .|.. .....| ||
sdyinaseil....pglylgslpp.....addlellkelgithivnlteelelg...flkcdpywpeeag..............................
adstgkfaartlTHYQYSQWAERGVPKSHVETYELMEMVK----KSEKPIVVHCSNGIGRSMAFIGTEYLARQveadpTIELTEALKHLHEHRWnGVQTN
.|.. . ||| . ..|..|... ....|..|||| |.||| ... .. .. . | ||.....|.|. .|..
............iqylhipipDhgvpdllehflefvefieealdekggpvlVHCsaGvgRsgtlvaaylmkkl.....glsleeaielvrerRp.ivpnp
SQLYWMT
.||...
gqlrqLy
|
|||||||||
| subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 1082-1278 | 7.6e-32 | 105.7 | In-house | 85-281 (298) | alignment | ||
Range on Protein: 1082-1278
Range on HMM: 85-281/298.0
APIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYlpmWPR-NDLQVGRFMIKMTNMDfiVQKNIMRRSFKVADS
| | .. . . . ||||| |...| |||| | ...... |||. .| | . | || . . |.. ... . . .. ... | .||...
dYiNAsflhaykgrnafiatqaPltetvedFWrmvteedigtiVmltnleeldktkyhky...wPdegketygeitvsllske..efadlivrklkvskk
TGKfAARTLTHYQYSQWAERGVPKSHVETYELMEMVKKS-----EKPIVVHCSNGIGRSMAFIGTEYLARQVEADPTIELTEALKHLHEHRWNGVQTNSQ
. . |.. . ....|...|||. . .|.. |..| .||..|.||.|.||| .|| . . .|... .... ...| | ..| . |||..|
kee.kerevrqlhftsWpdkgvpenatsvldllrkvrasqqqagnkpvivqCsaGvgRsGtfiaidsvlervkkeqvvDvfqvvkvlRkkrpgavqteeq
LYW
.
Yvf
|
|||||||||
| subfamily_Ptp69D_pd | Subfamily Ptp69D | 1082-1310 | 6.7e-31 | 102.5 | In-house | 77-303 (307) | alignment | ||
Range on Protein: 1082-1310
Range on HMM: 77-303/307.0
APIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYlpmWP-RNDLQVGRFMIKMTNMDFivQKNIMRRSFKVADS
| |... . . ..||| | |..|| .||| | .. ||. |||. |. .. . | || . | | ..|. . .. ... ..|...|.
dYinasfikgykekkkfiaaqdPveatigDfWRmiaeqevtlivmlsnlteknrkkcakY...Wpiedevqygdilvklvseek..hsdyiiReldvskk
TGK----FAARTLTHYQYSQWAERGVPKSHVETYELMEMV----KKSEKPIVVHCSNGIGRSMAFIGTEYLARQVEADPTIELTEALKHLHEHRWNGVQT
. . | .. |.| .| . ||.. .|.|.| |... |||||||.| ||| |. . | |..|. .... | |.|...| ||
keesgevedsrkvvqyhytgWkDskvPevargllklieqvrelyklnrsPivvhCsaGvgrsgifvaldsllqqlkaedkvdifetvkdLrsqRnllvqs
NSQLYWmtlgtMYRLIKEYGFDmKIYDQQMAMFNDVVK
| . .|| . .| |... ..| ..
leqYvf.....lyralldyssy.gdtdedvddledaie
|
|||||||||
| 0043147 | (Phosphotyrosine protein) phosphatases II | 1082-1279 | 1.1e-30 | 102.0 | In-house | 6-153 (172) | alignment | ||
Range on Protein: 1082-1279
Range on HMM: 6-153/172.0
APIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKveywknihndylpmwprndlqvgrfmikmtnmdfivqknimrrsfkvaDST
|.|...... .|.|||||| | . |..|||.|. .. . |||.. . .
dyinasyldlyyipdrfiatqgplrntladfwrmlkelgithivnltel................................................lyd
GKFAARTLTHYQYSQWAERGVPkSHVETYELMEMVKK-----SEKPIVVHCSNGIGRSMAFIGTEYLArqveadPTIELTEALKHLHEHRWNGVQTNSQL
... |. .|.| | ||| . .|..| ... ...|..|||| |.||. ... .. . | ||.... |.|...||. ||.
pellerlgiqylylpwpDhgvp.llellleflefidellalspggpvlVHCsaGvgRtgtlvaaylml......lglsleeavalvrekRpgavqnpsqy
YWM
..
rfl
|
|||||||||
| 0046846 | (Phosphotyrosine protein) phosphatases II | 1082-1278 | 9.5e-24 | 79.5 | In-house | 13-164 (176) | alignment | ||
Range on Protein: 1082-1278
Range on HMM: 13-164/176.0
APIHANWVPTPghphRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMWPRNDLqvgrfmikmtnmdfivqknimrrsfkvadst
|.||.. .. |.|||| |.. |..||..| .. ....|.. ||. . .| | . ....
dyinanlilgs....rpiatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpeleklgi...............................
gkfaartltHYQYSQWAERGVPKShVETYELMEMVKKSE---KPIVVHCSNGIGRSMAFIGTEylarQVEADPTIELTEALKHLHEHRW-NGVQTNSQLY
.|.. | . ||| . .||.|.... .|..|||| ||||. ... .| . . . |||... |.|. . ||| .|..
.........qylhlpwpDhgvpdl.elllellefirealkeggpvlVHCsaGigRtgtlvaay....llelekglsveealalvreqRplgavqtpeQyr
W
.
f
|
|||||||||
| subfamily_Sponge-PTP9_pd | Subfamily Sponge-PTP9 | 1082-1277 | 2.4e-21 | 70.7 | In-house | 71-283 (301) | alignment | ||
Range on Protein: 1082-1277
Range on HMM: 71-283/301.0
APIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMWPRNDLQVGRFMIKMTN----MDFIVQK---------
| |... . ..|||.|.|.. | ||| . .|. . .|||| . | |. . | | .. ..| | ....| ||....
eyinasyidgysekkkfiaaqgpmkktlvdfWrliwqekpvsivmvtnlkegtkskceqywpnseaeseefgpftvtlvneqvyPdfvirqlnvkiqdgs
--NIMRRSFKVADSTgkfAARTLTHYQYSQWAERGV---PKSHVETY--ELMEMVKKSEKPIVVHCSNGIGRSMAFIGTEYLARQVEADPTIELTEALKH
. . |.||| . ...... .| .| . || |. .. .. | . |.|||||....|| .. . |. |. ... . |
nngyierkfkvksdk...sswdvlqlqvtdWpqdGvvreprtvLqviddvihrqqkigggpvvVHCSdtVsrsGvYcsvsiglEQckaegVVdvfqvtka
LHEHRWNGVQTNSQLY
. . |.| |
vrrskpgaVtTLeqyt
|
|||||||||
| subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 1083-1280 | 2.3e-34 | 113.9 | In-house | 76-272 (318) | alignment | ||
Range on Protein: 1083-1280
Range on HMM: 76-272/318.0
PIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYlpmWP-RNDLQVGRFMIKMTNmDFIVQKNIMrRSFKVADsT
| ||... . . .||.|.|. |.|||| | . . |||. ...| |. . | || .. . |. ...... .. ... .. |.||| |
yinanyidGyrrkkayiaaqaPlpetieDfWrmvWeqnsavivmltqeeergkakvhry...WPskgsrsygklvvelke.evelsdyvl.refkvtr.t
GKFAARTLTHYQYSQWAERGVPKSHVETYELMEMVKKSE-----KPIVVHCSNGIGRSMAFIGTEYLARQVEADPTIELTEALKHLHEHRWNGVQTNSQl
.. . |. |.| .|...|||.| .. .|. |.| . .||||||| |.|| || . | ....|. .... . |.| |.| |||..|
eeeesrqvrqyhytsWpdegvpesgaslldlvrqvskaqqksgagpivvhCsaGvGrtGvfiavdillerikaealvDvfqtvkqlreqrnlmvqtedq.
YWMT
| .
yefi
|
|||||||||
| subfamily_PTPN12_pd | Subfamily PTPN12 | 1083-1277 | 1.3e-32 | 107.9 | In-house | 70-267 (290) | alignment | ||
Range on Protein: 1083-1277
Range on HMM: 70-267/290.0
PIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMWPRNDLQVGRFMIKMTNMDFIvQKNIMRRSFKVADStg
| ||.. . ....||.|.|. .| .||| | ....|| .||. |.|| |. . | | ..|..| | ..... . . ..... |..|| .
YinanfikgvegkleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkkCerYWpeegeeelefgefevtleeekav.dddflirtLkveaq..
kFAARTLTHYQYSQWAERGVPKSHVETYELMEMVKK----SEKPIVVHCSNGIGRSMAFIGTEYLARQVEAD---PTIELTEALKHLHEHRWNGVQTNSQ
. |... ..| .| ..|||.|. . ||.|.|.. ...|.||||| |.|| . | .| ....|. ..... . . .| ..| |||. |
.kesrkvyqfhYtaWPDhgvPssaksllelielvrelqesedaPlvvhCsaGvGrtGtiiaidyvrellkaekipeeldvfdlvlelrkqraalvqtkeq
LY
ye
|
|||||||||
| subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 1083-1277 | 2.9e-29 | 96.9 | In-house | 78-273 (290) | alignment | ||
Range on Protein: 1083-1277
Range on HMM: 78-273/290.0
PIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMWPRNDlqVGRFMIKMTNMDfIVQkNIMRRSFKVADSTG
|.| .. . ...||||.|.. | ||| . .| .| |||. .| |. . | | . .. .| | ||..| ... ....| ..| ...
yinAcyikgykekkqyiatqgpvsntlvdFWkliwqekvtiivmltniieegkvkCqqYWpdsdtka..ygefsikllnee.tln.eyierklevknkns
KFAARTLTHYQYSQWAERG-VPKSHVETYELMEMVK----KSEKPIVVHCSNGIGRSMAFIGTEYLARQVEADPTIELTEALKHLHEHRWNGVQTNSQLY
. |....|.|| . | . | |.. . . . ||.| . ...||||||...||| |. .. ... . |.. . ||.. . . |||. |.
agakqsvtqyqitnwdstgkvtnpqtillvieemyktqrkrgntsivvHCSdtvgrsavfcaaattinkcktegvidvfqvlksqRiqkpgsvqtvqqyq
|
|||||||||
| subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 1083-1276 | 7.8e-27 | 88.5 | In-house | 73-265 (515) | alignment | ||
Range on Protein: 1083-1276
Range on HMM: 73-265/515.0
PIHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMWPRNDLQVGRFMIKMTNMDfiVQKNIMRRSFKVADSTG
. | .|. . .||.| | .|. .||| . .|..| |.|| .. | | | | | . .. | . ... .. . ..| ..| .
yfnasyipsfdndkayiasqgPnkasvddfWrlvlqenvttiamvtklkegdkikcgkyWPdkpgdsvkfGsikvelvsle..actggikrkltvlkgdd
kfaARTLTHYQYSQWAERGVPKSHVETYELMEMVKKS----EKPIVVHCSNGIGRSMAFIGTEYLARQVEADPTIELTEALKHLHEHRWNGVQTNSQL
.||.| ... .| ..|||| |. || . . |...||| |.|| .| . ... .... . .. . ..| |||. |
...srtvtqfhfteWPdkGvpkhtssllklikevkadhgqythpliihcsaGvGrtGvvisidsvvahakttrmvdvfnfvtnirqkrpylvqtqeqy
|
|||||||||
| 0051082 | (Phosphotyrosine protein) phosphatases II | 1083-1278 | 4e-20 | 67.4 | In-house | 5-144 (151) | alignment | ||
Range on Protein: 1083-1278
Range on HMM: 5-144/151.0
PIHANWVPTPghphrFIATQSPinatCEDFWAMCMQYEVEHIVMVGRKVEYWknihnDYLPMWPRNDlqvgrfmikmtnmdfivqknimrrsfkvadstg
.|....| ..... | .||... .. . .||.. ..|. . .|...
yinfsyvtgg.....lyrsggp....ladflellkelgiktivnlrseeerg.....ycpeylpelg.................................
kfaaRTLTHYQYSQWAERGVPKSHVETYELMEMVKKS-EKPIVVHCSNGIGRSMAFIGTEYLARQveadptIELTEALKHLHEHRWNGVQTNSQLYW
....|... | . |.| | . |..|.. . ..|..|||| |.||. .... .... . | |||......|.. ||.| | .
....ievlhipildwpdpglplsfdavleflellldkkngpvlvHCsaGkgRTGtlvalylmllg......vsleealeeyrlkrpgvvqpnqqflf
|
|||||||||
| subfamily_PTPRD_pd | Subfamily PTPRD | 1084-1291 | 4.2e-39 | 129.6 | In-house | 79-280 (564) | alignment | ||
Range on Protein: 1084-1291
Range on HMM: 79-280/564.0
IHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMWpRnDLQVGRFMIKMTNMDfiVQKNIMRRSFKVaDSTGK
| |... . ... .|||| |.. |.|||| |....... |||. . .| |. ..| | . ..|........ .... |.||. . .
INAsfidgyrkrkayIAtqgPlaetiedFWRmvweqnsstiVmltkleEkgkvkchkYWPek.g.tetygeltVtleeee..eladyeirtfkl.kkkks
FAARTLTHYQYSQWAERGVPKSHVETYELMEMVKKS----EKPIVVHCSNGIGRSMAFIGTEYLARQVEADPTIELTEALKHLHEHRWNGVQTNSQlYWM
.|. ..... .| ..|||.| . .|.. |... ..|||||||.|.||. .|| ... ...... |... . .|.| ..| |||..| |
sesreVrqFhFtsWPdhgvpesatslLdlirkvralnepdagPivVhCSaGVGRTGtfividamlerikeektvDiyqyvkalrkqRnamVqteeQ.YiF
tlgtMYRLIKEY
... | |.
....iheailea
|
|||||||||
| 0051429 | (Phosphotyrosine protein) phosphatases II | 1084-1288 | 5.2e-33 | 110.2 | In-house | 7-226 (272) | alignment | ||
Range on Protein: 1084-1288
Range on HMM: 7-226/272.0
IHANWVPTPGH---PHRFIATQSPINATCEDFWAMcMQYEVEHIVMVGRK--------VEYWKNIHNDYLPMWPRNDLQVGRFMIKMTNMDFIVQKNIMR
|.|..|...|. |.|..... | ..|..|||.. .. . .||.. . || .|. .||.... . .. ... .|.. .... ...
iNardvggygrvvkpgrlyrsggplpltaadfwrl.kelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseellldyil
RSFKVADSTGKFAARTLTHYQYSQWAERGVPKSHveTYELMEMVKKsEKPIVVHCSNGIGRSMAFIGTEYLARQVEADPTIE--------LTEALKHLHE
| . . . .||...|..| .| .|||.. ||.|.. . ..|..|||| |..|. .. .|...|... .. | ||...| .
rellltlllsagearevmhlhytdwpdhgvpqea..llellellld.ggpvlvHCsaGkdRTGtvvallllllgvsletivddYlltnlyleeaveelra
HRWNGVQTNSQLYWMTLGTMYRLI
.| . ||| |... . |
qrpgavqteeqylflyeallellr
|
|||||||||
| subfamily_Cele-PTP-1_pd | Subfamily Cele-PTP-1 | 1084-1293 | 1.7e-30 | 101.1 | In-house | 49-265 (290) | alignment | ||
Range on Protein: 1084-1293
Range on HMM: 49-265/290.0
IHANWVPTPgHPHRFIATQSPI-------NATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHN----DYLPMWPRNDLQVGRFMIKMTNMdfIVQKNIMR
|||| | | . |.|.|||| |.| |.|| | .| .|...||.. | .| .. | |. ..|... . .| ... . .... .
iHAnrvtcp.nglrliltqsPqekitekrnStiekfwwmakqEkvkqvVmlcefeeksantslfaCakYvpesvgeelkfkgltvkCksk..ekeddvet
RSFKVAdsTGKFAARTLTHYQYSQWAERGVPKSHVETYELMEMVKKSEKPIVVHCSNGIGRSMAFIGTEyLARQVE--ADPTIELTEALKHLHEHRWNGV
| | .. |.||.....| .. |.... .|...||.|. |..||| .|| || |. . |. | ..|...|| | ..| . .
Relvvk..fddeeeftvtHsllkgWnklnvqedtktllsliqkvkasktpvivHcvdGiSrsAalaaii.lgyQkiaetsgsvkledvlkalrkqralai
QTNSQLYWMTLGTMYRLIKEYGF
... .| .. | . ..|...
tsalelafvdagivllaievldq
|
|||||||||
| subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 1084-1281 | 9.2e-26 | 86.0 | In-house | 56-249 (284) | alignment | ||
Range on Protein: 1084-1281
Range on HMM: 56-249/284.0
IHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGrkveywKNIHNDYLPMwpRNDLQVGRFMIKMTNMDFIVQknIMRRSFKVADSTGK
| | .. .....|||| | . | .||| | .|.. ||.. |. .| | . . . .|| .|.. .. . . |...... . .
inasfitGyqrkdkyiatqGPldntladfWrmiweyncstivllt......kdkcsqywpl..kivikeerfkvkvdsveesee..yvvrdielsedgke
FAARTLTHYQYSQWAERGVPKSHVETYELMEMVK------KSEKPIVVHCSNGIGRSMAFIGTEYLARQVEADPTIELTEALKHLHEHRWNGVQTNSQLY
|... . . | . |||.. .. |.. |. . ...|||||| |.||. ..| . | ... . ... . .. | . | . || | .
kdirkirqfhflgwpdvgvpdypsdlmrlvkkvrhltskenhranivvhcsagvgrtgvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqyk
WMTL
..
fiys
|
|||||||||
| subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 1084-1278 | 2.8e-25 | 84.1 | In-house | 82-275 (297) | alignment | ||
Range on Protein: 1084-1278
Range on HMM: 82-275/297.0
IHANWVPtpGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIhNDYlpmWPRNDLQ-VGRFMIKMtnMDFIVQKNIMRRSFKVADSTG
. | .|. | ||.|.|| | .|| .||||| ....| |||. . | |. | |. . . | ... . .. ..|...|. .
vnasfvk..gnkhrlittqmPmkatvadfWamvldeqvstivmlnddnerdkkc.ary...WsdkgvttfGdvsvvl..lsvsereGfikrelevtkgka
KfAARTLTHYQYSQWAERGVPK--SHVETYELMEMVKK-----SEKPIVVHCSNGIGRSMAFIGTEYLARQVEADPTIELTEALKHLHEHRWNGVQTNSQ
| | | . ||. .| .. |.. | .|.. |.| .| |..|||..|.|| .. . ... . .... . .|.| ..| . |||. |
k.arrvvkqyqfveWPdkaverkdsassllklisevrkdfsqnaegPllvhclaGvGrtgvlltidsvvaeakrekevdifglvkklrqerpylvqtkeq
LYW
.
ykf
|
|||||||||
| 0036282 | (Phosphotyrosine protein) phosphatases II | 1084-1278 | 2e-24 | 81.6 | In-house | 5-161 (174) | alignment | ||
Range on Protein: 1084-1278
Range on HMM: 5-161/174.0
IHANWVPTPGHPHRFIATQSPINatcedFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMwprndlqvgrfmikmtnmdfivqknimrrsfkvadsTGK
|.|... . |.||.| | . ||.|. .. ....||. . .| . .| |. . .
inaspldlsyitprliagqgpla.....fwemlkelgittvvmlleekelglykcinywpe....................................lre
FAARTLTHYQYSQWAERGVPKSHVeTYELMEMVKKS-----EKPIVVHCSNGIGRSMAFIGTEYLARQVEaDPTIELTEALKHLHEHRWNGVQTNSQLYW
. |. .|.| | .||| ... .|... |.. ..|..|||| |.||. .... .. |. . .... . .. |. .| ..||| ||...
dlerlgiqylylpwpDhgvpdlsi.llefvkfveealsedpggpvlVHCsaGvgRtGtlvaaylmlrgll.eslvdaldlvrelRlqrpgmvqtpsQyrf
|
|||||||||
| subfamily_CG7180_pd | Subfamily CG7180 | 1084-1275 | 3.1e-21 | 70.3 | In-house | 73-278 (296) | alignment | ||
Range on Protein: 1084-1275
Range on HMM: 73-278/296.0
IHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKnIHNDYLPMWPrnDLQVGRFMIKMTNMDFIvqKNIMRRSFKVADS---
| | .| . ... .| |. | . | ..|| . . |.. .|.. .. .. | ..|.| | | ......... |. | ||.
inavyvdsflkkkeyivteapkketvdefWrlvydeeisavvvLtktfdfak.mypsywpnks..keqygeifveiveekqy..anlkirtfkltkkiva
------TGKFAARTLTHYQYSQWAE-RGVPKSHVETYELMEMVK----K-----SEKPIVVHCSNGIGRSMAFIGTEYLARQVEADPTIELTEALKHLHE
| |.....|. .| || | ||...|. | |.|.||..|.| .|| .... . .|| . ... ||.| | .
lteqekqvkaetRivklfqlteWeledkvPlstnalielrrrvrlwrekvdedpeegPvvvvssdGasRsGvylaidanlelvekeeevdvFeavktlrr
HRWNGVQTNSQ
.| . |.. .
sRpqLvenvee
|
|||||||||
| subfamily_ptpA1_pd | Subfamily ptpA1 | 1084-1241 | 1e-11 | 39.2 | In-house | 78-250 (418) | alignment | ||
Range on Protein: 1084-1241
Range on HMM: 78-250/418.0
IHANWVPTpGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVE--------YWK-NIHNDYLPMWPRNDLQVGRFMIKMTNMDFIVQKNIMRRS
| ||.. .|..||.|| |. | ||| | . . |||. |. | || .| . . .. . .| . ... .. ...|. |
inanyidg.aypkqfictqgplpntiadfwrmvwenrcriivmlsresencrikcdrywpeqiggeqfsiygngnevfgtysvelveviqdpereiitrn
FKVadsTGKFAARTLTHYQYSQWAERGVPKSHVETYELME--------MVKKSE--KPIVVHCSNGIGRSMAFIGTE
.. | . .| .|.||| | .. .| .|. .. |. ||.|||| |.||. .| .
irl...tfegetrditqyqyegwpdhnipdhtqpfrqllhsitnrqnqiipssdrnvpiivhcsagvgrtgtfctav
|
|||||||||
| subfamily_Sponge-PTP4_pd | Subfamily Sponge-PTP4 | 1084-1203 | 1.9e-06 | 21.7 | In-house | 125-237 (244) | alignment | ||
Range on Protein: 1084-1203
Range on HMM: 125-237/244.0
IHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRkVEYWKNIHNDYLPM-WPRNDLQVgrfmiKMTNMDfiVQKNIMRRSFKVaDSTG
| | .| | .| || |. | ||| | .. |. .|..| || . | |. | .|. | .|. | ||| ... .|
inasfvgclgrtaeyiltqhpladtsmdfwkmmlerhvnvlvvlgs.veeedeywpdseplewyeeditv.....tltdrd..efknikasnlei.esdm
KFAARTLTHYQYSQWAERGV-P
. . ..|| .| |.| | |
neshqaltmfqisnwpsdgttp
|
|||||||||
| subfamily_Sponge-PTP-4_pd | Subfamily Sponge-PTP-4 | 1084-1201 | 2.8e-06 | 21.7 | In-house | 16-125 (130) | alignment | ||
Range on Protein: 1084-1201
Range on HMM: 16-125/130.0
IHANWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRkVEYWKNIHNDYLPM-WPRNDLQVGrfMIKMTNMdfivqKNIMRRSFKVADSTg
|.|..| |. .. || |. .|. ||| | .. |. .|..| || . | |. | .|. | . . .. ||| ... .
inasfvGllgrtaeylltqhpladtsmdfwkmmleryvnvlvvlgs.veeedeywpdsePlewyeediivt..ltdrdef.....knikasnleiesdl.
KFAARTLTHYQYSQWAERG
. . ..|| .| |.| |
neshqaltmfqisnwpsdg
|
|||||||||
| subfamily_Sponge-PTP5_pd | Subfamily Sponge-PTP5 | 1085-1276 | 3e-25 | 83.7 | In-house | 61-255 (283) | alignment | ||
Range on Protein: 1085-1276
Range on HMM: 61-255/283.0
HANWVP---TPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMwpRNDLQVGRFMIKMTNMdfIVQKNIMRRSFKVADST
| ..| . ...|..|||.. | ||| | . .. |||. . | . | | | . | | . . . .. ... . . ..
navfipvsksykqdkkyiiaqsPldrtvvdfWkmvfdekitaivmltklqedlrikCsqyWPk..rGsedyGeftvtlrke..ttsnsfiikelllrvns
GKFAARTLTHYQYSQWAERGvPKSHVETY---ELM-EMV-KKSEKPIVVHCSNGIGRSMAFIGTEYLARQVEADPTIELTEALKHLHEHRWNGVQTNSQL
.. |.|||. .| | | ... ... ... .. . |||||||.||||. .||. .. .. ... . .| . |.| ||| |
sakstlllahyqvidWleyg.eqaiinslvkfnkvislqteskkgPivvhCstgiGrtavfiaasasvkdaltesvvdvfavvkimreqrmmavqtldqy
|
|||||||||
| subfamily_PTPRA_pd | Subfamily PTPRA | 1087-1291 | 4.2e-25 | 83.3 | In-house | 92-294 (330) | alignment | ||
Range on Protein: 1087-1291
Range on HMM: 92-294/330.0
NWVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYlpmWPRND-LQVGRFMIKMTNMDFIVQKNImrRSFKV---ADSTG
.. . ..|||.| | . | |||| | ... |||. | .. . | || . . | ... .. .|. . | | | .|.|
sfidGykekdkfiaaqGPkeetvedfwrmiweqksativmltelkerkeekcaqy...wPdeGlvtyGnirvevedetvlvdytv..rkflvqqlpdatr
KFAARTLTHYQYSQWAERGVPKSHVETYELMEMVKKSE----KPIVVHCSNGIGRSMAFIGTEYLARQVEADPTIELTEALKHLHEHRWNGVQTNSQLYW
. ..| .. . . | . ||| . .|.. ||| . ||||||| |.||. .|| . . .|.|. ... |..|.| | . |||. | .
ekksrlvrqfhftswPdvGvPfepiGmlkllkkvkklnqqsagpivvhcsaGvGrtGtfivldavlervkaerkvdvfefvkrlrlqrpqmvqtdeqyef
mtlgtMYRLIKEY
.|. ..||
.....iykvlley
|
|||||||||
| subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 1088-1278 | 6.8e-30 | 99.1 | In-house | 44-233 (250) | alignment | ||
Range on Protein: 1088-1278
Range on HMM: 44-233/250.0
WVPTPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNiHNDYLPMwpRNDLQVGRFMIKMTNMDfiVQKNIMRRSFKVADSTgKFAAR
.. . . |||||.|..|| |||| | ...... |||. .| |. ..|.|. . . | .... . . . ... | .|.. . | |
flhgyderkafiatqgPlqatiedfWrmvleeksgtivmLtnLkesekt.yhqywPv..ekaekyGdvtvsllske..efadytkrklklskak.kader
TLTHYQYSQWAERGVPKSHVETYELMEMVKKSE-----KPIVVHCSNGIGRSMAFIGTEYLARQVEADPTIELTEALKHLHEHRWNGVQTNSQLYW
.. .... .| ..|||. ||.. |..|. .|..|.||.|.||| ||| . . ... . .... . .| | ..| . |....| .
ivrqlhfvvWPdkgvPevatavLellkkvqasqqqagnaPvivqCsaGvgrsGafiaidavlerlkkekvvdvfkvikvlrkdrphavesleqyvf
|
|||||||||
| 0049260 | (Phosphotyrosine protein) phosphatases II | 1091-1279 | 7e-27 | 89.4 | In-house | 4-142 (152) | alignment | ||
Range on Protein: 1091-1279
Range on HMM: 4-142/152.0
TPGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLpmwprndlqvgrfmikmtnmdfivqknimrrsfkvadstgkfaartlt
..|..||||| | . |..||| | .. . .|||. . .| .| .. |
gyampfefiatqgpgpntladfwrmlkelgittivmltellelgklkceqyi................................................
HYQYSQWAERGVPKSHVETYELMEMV----KKSEKPIVVHCSNGIGRSMAFIGTEYLArqveadPTIELTEALKHLHEHRWNGVQTNSQLYWM
.|.. .| |||... ..|.... .....|..|||| |.||. ... .. ..| ||.... |.|...|.. .||..
qylhlpwpDhgvpdlsqlllflllfieklaldkggpvlVHCsaGvgRtgtlvaaylml......lgvsleeavalvrekRpgavpnpgqlrfl
|
|||||||||
| subfamily_PTPN23_pd | Subfamily PTPN23 | 1091-1277 | 1.4e-26 | 87.9 | In-house | 79-270 (288) | alignment | ||
Range on Protein: 1091-1277
Range on HMM: 79-270/288.0
TPGHPhRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMWPRNDLQVGRfmIKMTNMDFIVQKNIMRRSFKVADsTGKFAARTLT
.|| | |||||.|.. | ||| | .. .. |||. | | |. . | | . . | ...| . .. ..| .|. .. | ....
spgcP.dfiatqaPlqstlnDFWlmvyeqkssviVmllskeelgkpkvdrYwPedkgetvkfgd..lsvtlksvretethvervlklet.ldadavksvs
HYQYSQWAERGVPKSHVETYELMEMVKK--------SEKPIVVHCSNGIGRSMAFIGTEYLARQVEADPTI-ELTEALKHLHEHRWNGVQTNSQLY
| |. .|.| |||.| . .... |.. |..|.||||| |.||. .| .|..|... . .. . ...| | | . ||...||
hlqltsWpelGvPasPetllqfldevesayeavqrksktPlvvhCsaGvgRtgvfalvyaavrelekgnglldiiqvvsrlreqRrfmvqekeqlk
|
|||||||||
| subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 1092-1278 | 1.4e-20 | 68.5 | In-house | 41-230 (237) | alignment | ||
Range on Protein: 1092-1278
Range on HMM: 41-230/237.0
PGHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMWPRnDLQVGRFMIKMTNMDFIVQknIMRRSFKVADSTGKFAARTLTH
| |...||.| |....|.||| | | |||. .| . .| | . | . . .. . . . ||. .. . . | .
dgtpkkyiaaqgplesscddfwqmvwqekcsvivmltgliegnelkchkywpstdq.paaygvltvslkkkeefsd..ytvrslllskrltlkevrlihq
YQYSQWAERGVPKSHVETYELM-EMVKKSEK-----PIVVHCSNGIGRSMAFIGTEYLARQVEADPTIELTEALKHLHEHRWNGVQTNSQLYW
||.. | .||||. . .....|.. | ..||| |.||. |. . . || . ... . .. . | | .||. | .
yqftswpdrgvpqqtaallrfrkniinrsphvsesgpwiihcsagvgrtgiflvidamlrqakekkvvdiynyvysieedrpyiiqtkdqyvf
|
|||||||||
| subfamily_PTPN14_pd | Subfamily PTPN14 | 1093-1276 | 5.4e-23 | 76.4 | In-house | 90-285 (300) | alignment | ||
Range on Protein: 1093-1276
Range on HMM: 90-285/300.0
GHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMW--PRNDLQVGRFMIKMTNMDfiVQKNIMRRSFKVADSTGKfAARTLT
|. . .|..|.|.. |..||| | . .|. |||. .. | |. |.| .. .. |.| . . . .. ...|. | ||.
gkersyivaqgPleltvqdfWqmvWeqgvqlivmlteeeedgkeksfkyfPkleskkktvefgkfkvttkfse..dsdsvittglklkhlpsk.eertvw
HYQYSQWAERGVPKSHVETYELMEMVK-------------KSEKPIVVHCSNGIGRSMAFIGTEYLARQVEADPTIELTEALKHLHEHRWNGVQTNSQL
| || |...|||. . . .|.|. .|. |..||||.|.||. | .. | .| . .|.. ..|..| | | ||| .|
hlqytDWpdhgvPeDvkgflsyLeevqsvrrktnseveskeskPPvlvhCsaGvGrtGvlilsdlliatlehneeidikkvlarLreqrmllvqtlaqY
|
|||||||||
| subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 1093-1281 | 5.7e-20 | 66.5 | In-house | 49-235 (239) | alignment | ||
Range on Protein: 1093-1281
Range on HMM: 49-235/239.0
GHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYlpmWPRNDLQVGRFMIKMTNMDfiVQKNIMRRSFkVADSTGKFAARTLTHY
| |. .|||| ..... ||| | | |||. .| |. .| || . . . . . . . | . . |.| | |. | . .|
gspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqy...wpdstskycnlrvtlrkte..vfadyiirtf.vmsqvgqteeryvyqy
QYSQWAERGVPKSHVETYELMEMVKKS----EKPIVVHCSNGIGRSMAFIGTEYLARQVEADPTIELTEALKHLHEHRWNGVQTNSQLYWMTL
... | ..|||. | . | .| |.||| |.||. ||. . . || . . |... . .| ..| | |||. | .. |
hftvwpdkgvpqyatavlglrrkitkdslpgarpwvihcsagvgrtgaflvidamlrqakkqktvdifnyvkairedrphmvqtseqyvfihl
|
|||||||||
| subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 1093-1281 | 5.7e-20 | 66.5 | In-house | 48-234 (239) | alignment | ||
Range on Protein: 1093-1281
Range on HMM: 48-234/239.0
GHPHRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYlpmWPRNDLQVGRFMIKMTNMDfiVQKNIMRRSFkVADSTGKFAARTLTHY
| |. .|||| ..... ||| | | |||. .| |. .| || . . . . . . . | . . |.| | |. | . .|
gspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqy...wpdstskycnlrvtlrkte..vfadyiirtf.vmsqvgqteeryvyqy
QYSQWAERGVPKSHVETYELMEMVKKS----EKPIVVHCSNGIGRSMAFIGTEYLARQVEADPTIELTEALKHLHEHRWNGVQTNSQLYWMTL
... | ..|||. | . | .| |.||| |.||. ||. . . || . . |... . .| ..| | |||. | .. |
hftvwpdkgvpqyatavlglrrkitkdslpgarpwvihcsagvgrtgaflvidamlrqakkqktvdifnyvkairedrphmvqtseqyvfihl
|
|||||||||
| subfamily_Nvec-PTP-3_pd | Subfamily Nvec-PTP-3 | 1096-1266 | 4.5e-16 | 53.6 | In-house | 4-182 (198) | alignment | ||
Range on Protein: 1096-1266
Range on HMM: 4-182/198.0
HRFIATQSPINATCEDFWAMCMQYEVEHIVMVGrkvEYWKNIHNDYLPMWPRNDLQVGRFMIKMTNMDFIVQKNI--MRRSFKVADSTGKFAARTLTHYQ
.|.|||| |. | ||| | . ||||| . || || .|| . .|.. |. | . . ..| ..| ..|||
rryiatqhplretladfwqmvwetgsghivmvn...ddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyq
YSQWAERGVPKSHVETY---ELMEMVKKSE----KPIVVHCSNGIGRSMAFIGTEYLARQVEADPT--IELTEALKHLHEHR
.. | |. |. . |. || | |..||||.| | . |. . | | | ..| | | | . |
ftswkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqar
|
|||||||||
| subfamily_Anemone-PTP-3_pd | Subfamily Anemone-PTP-3 | 1096-1266 | 4.9e-16 | 53.5 | In-house | 5-183 (199) | alignment | ||
Range on Protein: 1096-1266
Range on HMM: 5-183/199.0
HRFIATQSPINATCEDFWAMCMQYEVEHIVMVGrkvEYWKNIHNDYLPMWPRNDLQVGRFMIKMTNMDFIVQKNI--MRRSFKVADSTGKFAARTLTHYQ
.|.|||| |. | ||| | . ||||| . || || .|| . .|.. |. | . . ..| ..| ..|||
rryiatqhplretmadfwqmvwetgsghivmvn...ddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyq
YSQWAERGVPKSHVETY---ELMEMVKKSE----KPIVVHCSNGIGRSMAFIGTEYLARQVEADPT--IELTEALKHLHEHR
.. | |. |. . |. || | |..||||.| | . |. . | | | ..| | | | . |
ftswkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqar
|
|||||||||
| subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 1096-1162 | 3.9e-09 | 30.7 | In-house | 104-165 (350) | alignment | ||
Range on Protein: 1096-1162
Range on HMM: 104-165/350.0
HRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYlpmWPRndLQVGRFMIKMTNM
...||||.|. | .||. .... .|. |... .||. . . | |.. ... . .|....
fkYiatqaPlpstvddfykvillnkvkvilsltsdvelnlekcyrY...Wqe..gsydditvklask
|
|||||||||
| subfamily_eak_pd | Subfamily eak | 1096-1231 | 2.2e-08 | 27.9 | In-house | 93-222 (332) | alignment | ||
Range on Protein: 1096-1231
Range on HMM: 93-222/332.0
HRFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMWPRNDLQVGRFMIkmTNMDFIVQKNIMRRSFKVadSTGKFAaRTLTHYQYS
...| | . . || | .. ||.. .|| . .. |.| |. |. | . . . .|. .... | ... | | . . ||..
rkyiltGiasedkvfafwqmvleqkspaivqlledvelkleksdkyfpdktreelkfGildv..erkefvkrniletrllel..skGnet.hrvlhykvf
QWAERGVPKSHvETYELMEMVKKSEKPIVVHCSNGI
|.| .|| . . | ...|. . .. . .
Gwtettlpkye.dflalrkvmkevGvlllivmksal
|
|||||||||
| subfamily_PTPRN_pd | Subfamily PTPRN | 1097-1277 | 7.7e-19 | 62.5 | In-house | 101-282 (297) | alignment | ||
Range on Protein: 1097-1277
Range on HMM: 101-282/297.0
RFIATQSPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYlpmWPRNDLQVGR-FMIKMTnMDFIVQKNIMRRSFKVADSTGKfAARTLTHYQYS
.||||.|...| ||| | . | ||.. | | . . | || . .| . ... . | .. . ||| . . . .||.| . .
ayiatqgplastvadfwqmvweqGvvvivnltrleeegvkqckry...wpdeGsevyhiyevhlv.sehiwcddylvrsfylknlqts.etrtvtqfhfl
QWAERGVPKSHVETYELMEMVKKSE----KPIVVHCSNGIGRSMAFIGTEYL-ARQVEADPTIELTEALKHLHEHRWNGVQTNSQLY
| |.||| | |. | || |||||||.| ||. ..| . . .| . |... .|.|| . | . |.|..|.
swpeegvPasaksllefrrkvnksyrGrscpivvhcsdGaGrtGvyilidlvlnrllkGvkeidiaatlehlrdqrpglvktkdqfe
|
|||||||||
| subfamily_Cele-PTP-7_pd | Subfamily Cele-PTP-7 | 1103-1283 | 2.4e-16 | 54.1 | In-house | 98-284 (302) | alignment | ||
Range on Protein: 1103-1283
Range on HMM: 98-284/302.0
SPINATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMWPRNDLQVGRFMIKMTNMDFIVQKNIMRRSFKVA------DSTGKFAARTLTHYQYSQ
| . |.| .||. ||.| .| . || .. .| .. |. ||. .| ... ... ..|||. . . | .|. ..|
vpkkstlekhwalieqynvaivvqlcsfvedeekkcaeyysdkvggelkfgrytvktvsvktdleeftdkksfklytveiknekkkkkvkktvdilafsa
WAERGVPKSHVETYELMEMVKKSEKPIVVHCSNGIGRSMAFIGTEYLARQVEADPTIELTEALKHLHEHRWNGVQTNSQLYWMTLGT
| . | || . ... . | ..||||.|.||. ... | . . .| . .. . . |. ||...|| .. |
wpdhGapkeaytaldilkfcesykknvlvhcsaGvGrtGtlvaikyGiqlcskkkvtdllsivlpvrqcryGavqdeqqliylllcv
|
|||||||||
| subfamily_Cele-PTP-9_pd | Subfamily Cele-PTP-9 | 1106-1276 | 5.5e-22 | 73.1 | In-house | 38-210 (255) | alignment | ||
Range on Protein: 1106-1276
Range on HMM: 38-210/255.0
NATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMWPRNDLQVGRFMIKMTNmdfiVQKNIMRRSFKVADSTG-KFAARTLTHYQYSQWAERGVPK
| . |. . .| . | .||.. | .. . |.|. . |.. . |. ... | .. | | ..|..||.| | |. |.
sltvdkfyqtivqtktevvvmlcdfaeegvekcssyfplekdeklkladvnvtttk....ssadvvlrtleitstlgekkkthtvkhysykGWieknaPe
SHVETYELMEMVKKSeKPIVVHCSNGIGRSMAFIGTEYLAR----QVEADPTIEL--TEALKHLHEHRWNGVQTNSQL
| ... .|..| |..|||||.||||| ||. .|.. . ... .|.|| . |..| ..| ..| ||
lareilnilkvvrds.ksvvvhCstGiGrsaafvlaelvyqkmirsldttetveldylslleelrskrkraihtPlql
|
|||||||||
| subfamily_hpo-7_pd | Subfamily hpo-7 | 1107-1276 | 3.3e-19 | 63.8 | In-house | 45-216 (263) | alignment | ||
Range on Protein: 1107-1276
Range on HMM: 45-216/263.0
ATCEDFWAMCMQYEVEHIVMVGRKVEYWKNIHNDYLPMWPRNDLQVGRFMIKMTNMDFivqkNIMRRSFKVADSTG-KFAARTLTHYQYSQWAERGVPKS
| . |. . | . | .||.. | .. . |.|. . ... . |.. ... .. .. | | .|..||.| | |. |.
qtidkfyqtivqtktevvvmLcDfneegvekcssyfPlekdekqklanvnvcttkvqs....dvllktlellstlgeKkkthtvkhysykgWiekndpel
HVETYELMEMVKKSeKPIVVHCSNGIGRSMAFIGTEYLAR----QVEADPTIEL--TEALKHLHEHRWNGVQTNSQL
| .........| |..|||||.||||| || .| . . ... .|.|| . |..| ..| ..| ||
areilnilkvarns.kslvvhcstGiGrsaafsvaElvyqkmirsldttstveldylsLleelrssrkraihtPmqL
|
|||||||||
| 0048076 | (Phosphotyrosine protein) phosphatases II | 1161-1280 | 3.7e-16 | 54.6 | In-house | 21-136 (145) | alignment | ||
Range on Protein: 1161-1280
Range on HMM: 21-136/145.0
NMDFIVQKNIMR-RSFkvaDSTGKFAARTLTHYQYSQWAERGVPKSHVETYELMEMV---KKSEKPIVVHCSNGIGRSMAFIGTeYLARQveadPTIELT
..... . .| . .. |. .. |. ..|.| | .||| .. .|..|.. |...|..|||| |.||. .... || .. . |
dlellkdlgittvlnl...tselellerlgiqylylpwpDhgvpdllellleflefieealkeggpvlVHCsaGvgRtgtlvaa.ylmll....lgvsle
EALKHLHEHRWNGVQTNSQLYWMT
|||......|...|.. .||...
ealelvrsqrpgavpnpgqlrfly
|
|||||||||
| 0048179 | (Phosphotyrosine protein) phosphatases II | 1177-1279 | 4.7e-15 | 51.1 | In-house | 37-137 (144) | alignment | ||
Range on Protein: 1177-1279
Range on HMM: 37-137/144.0
VADSTGKFAARTLTHYQYSQWAERGVPKSHVETYELMEMVKKS---EKPIVVHCSNGIGRSMAFIGTEYLArqveaDPTIELTEALKHLHEHRWNGVQTN
. . | |. ..|.. | .||| . .|..|.... ..|..|||| |.||. ... . . | |||......|...|..
teeyepefleregiqylhlpwpDhgvpdllellleflefieealeeggpvlVHCsaGvgRtgtlvaaylmk.....klglsleealalvrsrrpgavpnp
SQLYWM
.||...
gqlrfL
|
|||||||||
| subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 1184-1280 | 3e-09 | 30.7 | In-house | 86-187 (440) | alignment | ||
Range on Protein: 1184-1280
Range on HMM: 86-187/440.0
FAARTLTHYQYSQWAERGVPKSHVETYELMEMVKKS-----EKPIVVHCSNGIGRSMAFIGTEYLARQVEADPTIELTEALKHLHEHRWNGVQTNSQLYW
.||| .|.| | ..|||| .... |..| . |..|||| | ||. | . . |... |.. .. ... | . ||| | .
iesrtlkqyhyqgwpdkgvpkfagpvlkmiqdvnesqekagngpllvhcsagagrtgviiavdsilreakrsdqidifsfinsmrnnrpqmvqtpeqyaf
MT
.
vh
|
|||||||||
| PTPc_DSPc_SM00012 | 1189-1276 | 2.6e-19 | 64.7 | In-house | 2-96 (105) | alignment | |||
Range on Protein: 1189-1276
Range on HMM: 2-96/105.0
LTHYQYSQWAERGVPKSHVETYELMEMVKKSEK------PIVVHCSNGIGRSMAFIGTEYLARQVEAD-PTIELTEALKHLHEHRWNGVQTNSQL
..||.|..| . |||.. . ||.. |||... |.|||||.|.||. |. ..| .|.|. .... . .|.| ..| . |||. |
vkhyhytgwpdhgvPeesdsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgmvqteeqy
|
|||||||||
| PTPc_motif_SM00404 | 1191-1274 | 8.8e-07 | 23.9 | In-house | 51-128 (140) | alignment | |||
Range on Protein: 1191-1274
Range on HMM: 51-128/140.0
HYQYSQWAERGVPKSHVETYELMEMVKKSEKPIVVHCSNGIGRSMAFIGTEYLARQveadpTIELTEALKHLHEHRwNGVQTNS
... .. . . | .... .| ..|... ..||| |. || ..| ... .. ..| ||.. ..| | . .. |
qiplddnekdklskyldkvldfienaekkggkvlVHCqaGvSRSatliiaYlmryr.....qlslaeayefvkerR.piispnl
|
|||||||||
| subfamily_CG42327_pd | Subfamily CG42327 | 1217-1278 | 2.2e-06 | 21.6 | In-house | 244-306 (319) | alignment | ||
Range on Protein: 1217-1278
Range on HMM: 244-306/319.0
KKSEKPIVVHCSNGIGRSMAFIGTEYLARQVEAD-PTIELTEALKHLHEHRWNGVQTNSQLYW
..| |.|||||.|.||. | .. |..| .... . . .. . | . |.| | .
resqGPlvvhcsdGvGrtGlviasdiairsleeskrsvdiPqlvssvrrdrasavltkeqyef
|
|||||||||