Synonym: CELE_ZK354.8, CELE_ZK354.8
Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
| Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
|---|---|---|---|---|---|---|---|---|---|
| subfamily_Cele-PTP-18_pd | Subfamily Cele-PTP-18 | 179-461 | 2.2e-59 | 195.7 | In-house | 2-295 (305) | alignment | ||
Range on Protein: 179-461
Range on HMM: 2-295/305.0
KKKRTEVICSWIRLVLQNGVAGLKKEYRDSPNEAPEDIATSFL--GNPTRNRYRNIPCCDITRVKLTD-DPHFYIHANLVSSGPNPRRFICTQAPLNGTI
||.. | ... .|..| |||..|. . .| . .|||... | | |||| || ||||| ||. ||.|||||||||. |
kkqqkkqilkfvkrtlekgpaglraefvamkrfndfekmkafkeaqeagknrykdvgcldnnrvklegpwpheyihanyvstptnpkrfictqaplektc
EEFWKMIIVTGIEYIVMLCELVEKGKPKSAEYFPSQIGQTTK---IGRLCTVTKESRVDID----KTLVMSTMRISKPGDNAVVKIVKHIHWRNWPDHGV
.|| | . .|.| |||.|.||| | .|||.|. ... . |. .| || | .. ... . | . .. |.| || .||| ||
adfwymclqdkveaifmlcnllekgakkcleyfaskdkdvlefeekgqkisvkfessvtlkfrkdakakvtetvlviegpgekarkvthyhwidwpdrgv
PDNFLSPFRLLTVVKNCTKPIVVHCSAGVGRTGTLALILIILESICLPDFIG-VPRLLAKLREERFRAVQTEMQYLYAHRCVLEYLALKKYVQS
| |. . ||. . |||||||||.||||.. .. ||. . . | ..| |.||.| ..||. |||. |. .|.|. || ..
paadlailellekarpskgpivvhcsagigrtgsvvmleyildqllagqiiedtdkilqkireqrnnsiqtdaqylfvhqvilnyfrkkkllde
|
|||||||||
| 0039614 | (Phosphotyrosine protein) phosphatases II | 180-456 | 1.1e-72 | 240.3 | In-house | 13-292 (297) | alignment | ||
Range on Protein: 180-456
Range on HMM: 13-292/297.0
KKRTEVICSWIRLVLQNGVAGLKKEYRDSPNEAPEDIATSFLGNPTRNRYRNIPCCDITRVKLTDDPHF-----YIHANLVSSGPN-PRRFICTQAPLNG
....|. ...| .|. .|..|. . .. |. . . | ..|||..|...| .||||.. ... ||.|..|. .|.||.||.||..
piplsvldlllllekansktllllefeellslkpdysiallpenkdknrykdilpydhsrvklkpedgvdldsdYinAsyvdgydlltrkfIatqgPlpe
TIEEFWKMIIVTGIEYIVMLCELVEKGKpKSAEYFPSQIGqttKIGRLCTVTKESRVdiDKTLVMSTMRISKpgdNAVVKIVKHIHWRNWPDHGVPDNFL
|.| ||.|. |...||||..|||.|. | |.|.|. | . |... ... . .. .. |..... | ...|.|... .|||||||...
tvedFwrmvweqgvtvivmLtklvelgr.kcaqywpeegg...tygdftvtllkveh..ldgytvrtlevtn...ngesrtvthfqytgwpdhgvppsle
SPFRLLTVVKN------CTKPIVVHCSAGVGRTGTLALILIILESICLPDFIGVPRLLAKLREERFRAVQTEMQYLYAHRCVLEYLALK
. ...| |.. .|..||||||||||||.......|| . . |. ...||| | ||||. || . ....||.| |
llleflelvrealaelpkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavqtpsqyrflydallellkrk
|
|||||||||
| subfamily_Cele-PTP-8_pd | Subfamily Cele-PTP-8 | 181-470 | 3.4e-158 | 520.1 | In-house | 1-288 (288) | alignment | ||
Range on Protein: 181-470
Range on HMM: 1-288/288.0
KRTEVICSWIRLVLQNGVAGLKKEYRDSPNEAPEDIATSFLGNPTRNRYRNIPCCDITRVKLTDDPHFYIHANLVSSGPNPRRFICTQAPLNGTIEEFWK
|..|||..|||||||..|.|||||||||||||..||..||..||||.||.|.|.||||||||.|||.|||.||.|||....||.||.||||||||||.||
kkkevinawirlvlqiaveglkkeyrdspneasidiidsfianptrdryenlprcditrvklsddpdfyiaanvvssakykrrlicaqaPlngtieelWk
MIIVTGIEYIVMLCELVEKGKPKSAEYFPSQIGQTTKIGRLCTVTKESRVDIDKTLVMSTMRISKPGDNAVvkIVKHIHWRNWPDHGVPDNFLSPFRLLT
|......|||||||||.||||.||||||||..|....|||||||.|..|.||||....|..||||.|...| |||..|...|.|.|||.|.|||.|||.
mllesdveyivmlcellekGkeksaeyfPsklGekarigrlctvvkkkradidklvkvsllriskegeekv..ivkilhlleWdddgvPenylsplrlle
VVKNCTKPIVVHCSAGVGRTGTLALILIILESICLPDFIGVPRLLAKLREERFRAVQTEMQYLYAHRCVLEYLALKKYVQSREDFAKFAK
|.|...||||||.||||||||||.||||.|||..|.||.|...||||||||||.|.||||||||.||||||.|.||||...||||.|.|.
vlkslqkPivvhssaGvGrtgtlililialeslrlddflgirsllaklreerfkaiqtemqylyvhrcvleelllkkykvlredfvklae
|
|||||||||
| subfamily_Cele-PTP-11_pd | Subfamily Cele-PTP-11 | 181-474 | 2.8e-59 | 195.4 | In-house | 1-298 (312) | alignment | ||
Range on Protein: 181-474
Range on HMM: 1-298/312.0
KRTEVICSWIRLVLQNGVAGLKKEYRDSPNEAPEDIATSFLGNPTRNRYRNIPCCDITRVKLTDDPHFYIHANLVSSGPNPRRFICTQAPLNGTIEEFWK
.|.|.| | |. | |||. | .. |.|| ||| || | | | |. | ||||||.| .| ||.|||.||. |. ||.
qraemikkwasavmmstpqqltkeykavgnivsdsectaflkfkdlnrypniqcwdrgrftlagdenfyihanfvkictkperfvctqgplentcthfwq
MIIVTGIEYIVMLCELVEKGKPKSAEYFPSQIGQTTKIGRlcTVTKESRVDID---KTLVMSTMRISKPGDNAVVK--IVKHIHWRNWPDHGVPDNFLSP
. . | |..|| .|| | |.|.| .| | |. .|. |. | |. | .| . ..| | |||||.|| .
lalslgstsiillcgfvedgsekcakyisdivgfvdledh..rvyteycteieiggkskdkithrvlkvvvkatgqesklnhyqwaswpdhgmpdscdta
FRLLTVVKNCTKPIVVHCSAGVGRTGTLALILIILESICLPDFIGVPRLLAKLREERFRAVQTEMQYLYAHRCVLEYLALKK-YVQSREDFAKFAKDYEQ
.|||. ||. ||.. ||||||||||||||| .. .. | | . || .| |.|.. ||.|| |||||.| | | .. ....|| . | .
lrllsavkkdkkpviahcsagvgrtgtlaliesmiaalrhprkqnvkdsfvllrkdrarsvrvfpqyvyalrcvleflyskglykrneqewtkfketyak
|
|||||||||
| 0045450 | (Phosphotyrosine protein) phosphatases II | 182-453 | 1.1e-73 | 244.0 | In-house | 10-304 (307) | alignment | ||
Range on Protein: 182-453
Range on HMM: 10-304/307.0
RTEVICSWIRLVLQNGVAGLKKEYRDSPNEAP----EDIATSFLGNPTRNRYRNIPCCDITRVKLTD-----DPHFYIHANLV--------SSGPNPRRF
..........| |.....||.||... ... . | ..... | ..|||..|...| |||||.. ... ||.|. | .. ..|.|
dalkllllvllllldfltgllkefekllsvtvfllgeysiallpenkdknrykdilpydhtRVklssldgsledsdYiNAsyvrvpllllldgydlkrkf
ICTQAPLNGTIEEFWKMIIVTGIEYIVMLCELVEKGKPKSAEYFPSQiGQTTKIGRLCTVTKESRVdiDKTLVMSTMRISKPGDNAVVKIVKHIHWRNWP
|.||.||..|.|.||.|. |...||||.||||.|..| |.|.|. |.. .|... ... . .. ... |.... . . . .|.|.|. .||
IatqgPlpetvedFwrmlweqgvtvivmltelvelgrekcaqywPde.geeltygnftvtllseeh..ldgytvrtlevtdldgtgesrtvthfhytgwp
DHGVPDNFLSPFRLLTVVKN------CTKPIVVHCSAGVGRTGTLALILIILESICLPDF---IGVPRLLAKLREERFRAVQTEMQYLYAHRCVLEYL
|||||..| . .... |.. . .|..||||||||||||.......|. . . .. ...||| | |||.. || . ....||.|
dhgvppsfeelldfieevrkaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrflyeallell
|
|||||||||
| subfamily_Cele-PTP-10_pd | Subfamily Cele-PTP-10 | 184-459 | 3.3e-61 | 201.6 | In-house | 9-294 (305) | alignment | ||
Range on Protein: 184-459
Range on HMM: 9-294/305.0
EVICSWIRLVLQNGVAGLKKEYRDSPNEAPEDIATS-FLG------NPTRNRYRNIPCCDITRVKLTD-DPHFYIHANLVSSGPNP-RRFICTQAPLNGT
.. ... |. || |..|.|. . . |.. | . |.|||...|| | . ||| . | ||||| | | .||||.| ||. |
piveqfvlraldvgvdklreefrglakytrpdmtqvafnanqsadiaitknryqdvpcqdqsavkldkpspsdyihanyvgcpmipekrficaqgpldqt
IEEFWKMIIVTGIEYIVMLCELVEKGKPKSAEYFPSQIGQTTKIGRLCTVTKE---SRVDIDKTLVMSTMRISKPGDNAVVkiVKHIHWRNWPDHGVPDN
|.||| |.| .| ||||| || || | |.|.| |. .. . | . .. | . ....... ||. . |.|..| .||| |||
idefwwmviqnkveqivmlcktvelgklkcaqywpaaqgeklelksgivvenvsgskpmerdaeiqitllnltysgdqkms..vrhlqwtewpdrgvppc
FLSPFRLLTVVKNCTKPIVVHCSAGVGRTGTLALILIILESICLPD-FIGVPRLLAKLREERFRAVQTEMQYLYAHRCVLEYLaLKKYV
|. . ||. .. |||||||||.|||||. | ||| |. .| |. ||..| ..|...|||. || .|.|. |.||
kltslellsairgskvpivvhcsagigrtgtivaieyilekiaenkpcppmpelvkalrdqrafsiqndvqylfihrvmlnyf.lekyk
|
|||||||||
| subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 184-459 | 1.3e-54 | 179.8 | In-house | 12-289 (290) | alignment | ||
Range on Protein: 184-459
Range on HMM: 12-289/290.0
EVICSWIRLVLQNGVAGLKKEYRDSPNEA-PE-DIA-TSFLGNP--TRNRYRNIPCCDITRVKLTDD-PHFYIHANLVSsGPNPrRFICTQAPLNGTIEE
|.. . | . .| .| ||| . | . | |. ..|||....| |.||| | | . |.||| | | .. || || .|. |. .
eafekfasdvvkknvdelakeyleklkpylpvqylerkifdkntefkknrykdvvcndktrvilkdGydGdyvhanyvk.Glka.mfiltqGalkdtvid
FWKMIIVTGIEYIVMLCELVEKGKPKSAEYFPSQIGQTTKIGRLcTVTKESRVDIDKTLVMSTMRISKpGDNAVVKIVKHIHWRNWPDHGVPDNFLSPFR
.|.|.. ... .|||||||.|.||.| ..|.| . |.. .| . ||. | |. ... |. . . |. ...||.. . |||. |. |. .|
iwrmvlqekvaaivmlceliedGkakceqyypekeGevltfGei.tvlcseeddkdaniikktlsvrd.kdsGkehklkhlkikswpdksvalstlallr
LLTVVKNCTKPIVVHCSAGVGRTGTLALILIILESICLPDFIGVPRLLAKLREERFRAVQTEMQYLYAHRCVLEYLALKKYV
.| .... . |.|||||||.|||||.. | . |. . . . | ||. | .|| ..||| . .|.. ||.
tlrilrkasGpvvvhcsaGiGrtGtfvaievglqilldGkeldlldlvralrnsrlnsvqvdiqylalveilldlGkdfkyi
|
|||||||||
| 0051299 | (Phosphotyrosine protein) phosphatases II | 185-453 | 2.3e-75 | 249.0 | In-house | 9-286 (288) | alignment | ||
Range on Protein: 185-453
Range on HMM: 9-286/288.0
VICSWIRLVLQNGVAGLKKEYRDSPNEAPE--DIATSFLGNPTRNRYRNIPCCDITRVKLTD----DPHFYIHANLVSSGPNPRRFICTQAPLNGTIEEF
...... .|.||..||..|... .. | |... | ..|||..|...| .||||.. ... ||.|.... ...|.||.||.||..|.|.|
ellklvlkllangltglleefeellsllpdltlsaallpenleknRysdilpydhsRVkLsvldgvegsdYinAsyidgynlkrkfIatqgPlpntvedF
WKMIIVTGIEYIVMLCELVEKGKPKSAEYFPSqiGQTTKIGRLCTVTKESRVdiDKTLVMSTMRISKPG---DNAVVKIVKHIHWRNWPDHGVPDNFLSP
|.|. ....||||..|||.|. |.| |.|. |.....|... ... | ... .. |..... . . ...|.|.|. |||||||||.. .
WrmvweqnvrvIvmltklvelgrekcaqYwpl..ggsltygditvtllseev..lddytvrtlevtnldlldgdgesrtvthfhytnwpdhgvpdspell
FRLLTVVKNC----TKPIVVHCSAGVGRTGTLALILIILESICLPDFIGVPRLLAKLREERFRAVQTEMQYLYAHRCVLEYL
...| |... .|.|||||||||||||.......|| . . |......||| |. .|||..||.. ....||||
ldflrlvrkalasgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlreqRpgmvqtpeqyrfvyealleyl
|
|||||||||
| subfamily_Cele-PTP-6_pd | Subfamily Cele-PTP-6 | 185-476 | 1.2e-63 | 210.0 | In-house | 2-298 (307) | alignment | ||
Range on Protein: 185-476
Range on HMM: 2-298/307.0
VICSWIRLVLQNGVAGLKKEYRDSPNEAPEDIAT-SFLGNPTRNRYRNIPCCDITRVKLTDDP--HFYIHANLVSSGPNPRRFICTQAPLNGTIEEFWKM
|. |.. |. || |. |.| . .|| ... .| |. .|||....| | .|. .. | ||||| . .|..|||.| ||. |. .|| |
vvkpwvqrtldkgvqalvdefrvlakktpegvtveafsantdknryqdvkcqdkgrivvkfdglasdyihanylgiaikpkkficaqgplentqysfwam
IIVTGIEYIVMLCELVEKGKPKSAEYFPSQIGQTTKIGRLC---TVTKE--SRVDIDKT-LVMSTMRISKPGDnavVKIVKHIHWRNWPDHGVPDNFLSP
.| .| ..|||...| .| | .|.| . ||. | .|.. .. |. . ..|... .. . ..|. | ||||.|||. |.
aiqekvesvimlckvielakikceqywpleegqklvfgeapntisvanlgakklapdedlinvttlkvdwaqk...srtiqhlqwenwpdrgvpqinlta
FRLLTVVKNCTKPIVVHCSAGVGRTGTLALILIILESIC-LPDFIGVPRLLAKLREERFRAVQTEMQYLYAHRCVLEYLaLKKYVQSREDFAkFAKDYEQ
|| |. | |.||||||||||.||. | .. . . . . .|. .||..| |.|||.|||| || .|||. |..| .. |.. ..|.||.
inlleavrydtnpvvvhcsaGvGrsGtivaislvqdkmiaGinckdmkklveelrsqrhyaiqteaqylylhrvlleyf.lelyketyeell.ltknyee
AL
ky
|
|||||||||
| 0040438 | (Phosphotyrosine protein) phosphatases II | 186-459 | 1.4e-76 | 253.1 | In-house | 5-280 (317) | alignment | ||
Range on Protein: 186-459
Range on HMM: 5-280/317.0
ICSWIRLVLQNGVAGLKKEYRDSPNEAPEDIA-TSFLGNPTRNRYRNIPCCDITRVKLTDDP----HFYIHANLVSSGPNPRRFICTQAPLNGTIEEFWK
.. .. ..|.... .|..|..| .. .... .... |. .|||..|...| .||||.... . ||.|..|. .|.||.||.||..|.| ||.
lllalldllksdftalleefedllslkldtysvaelpenkdknrypdilpydhsRVkLsplggdldsdYInAsyvdgpnlkrkfIatqgPlpntvedFwr
MIIVTGIEYIVMLCELVEKGKPKSAEYFPSqiGQTTKIGRLCTVTKESRVdiDKTLVMSTMRISKPgDNAVVKIVKHIHWRNWPDHGVPDNFLSPFRLLT
|. |...||||.||.|.|..|.|.|.|. |.|...|... ... . .. .. |..... .. . .|.|.|. .|||||||... . ...|
mvweqgvtvivmLteleelgrekcaqYwpl..getltygdftvtllseee..lagitlrtlevedl.gdsesrtvthfhytgWpdhgvppspdllldfle
VVKNC----TKPIVVHCSAGVGRTGTLALILIILESICLPDFIGVPRLLAKLREERFRAVQTEMQYLYAHRCVLEYLalKKYV
|... .|..||||||||||||.......|| . .. |. ...||| | ||||..|| . ....|||| |...
avrealedpggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrflydalleyl..krkl
|
|||||||||
| subfamily_Cele-PTP-14_pd | Subfamily Cele-PTP-14 | 188-452 | 4.4e-44 | 145.3 | In-house | 16-289 (310) | alignment | ||
Range on Protein: 188-452
Range on HMM: 16-289/310.0
SWIRLVLQNGVAGLKKEYRDSPNEAPE-DIATSFLGNPTRNRYRNIPCCDITRVKLTDDP---HFYIHANLVSSGPNPRRFICTQAPLNGTIEEFWKMII
.| . |. || |.|| . .. . .||| .. | | .||||. | . ||||| | . |||.| ||. || .||.||.
nfiiateklgieglvkqyrkldakqdssltyeaykkymhknrysdvvcldtsrvklkidksryedyihanyvktnylrstficsqgplqhtiidfwrmif
VTGIEYIVMLCELVEKGKPKSAEYFPSqIGQTTKIG--RLCTVTkESR-----VDIDKTLVMSTMRISKPGDNAVVKIVKHIHWRNWPDHGVPDN--FLS
| |..|| .|.|.||. |.|| .| | | |. .. || ... |.| . . . | |. |.| |||| ||||.
qeraesilllckvgeegrpkcvgywps.lgvtetygcirvtnls.esseefeicnlavtfvpdnvpvdeqpanlkelrvslikwpnwpdrgvpdekchtv
PFRLLTVVKNCtkPIVVHCSAGVGRTGTLALILIILESICLPDFIGVPRLLAKLREERFRAVQTEMQYLYAHRCVLEY
| |||. |. | |||||||..|..... . . .. . . . . . ..|. .|. .|||.|||. .| . .
pqrllaqvrhg..pcvvhcsagkdrlyvvvalklkidkldrglkvdaeevktellksraiciqtelqyliidrvriif
|
|||||||||
| subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 189-463 | 9.5e-51 | 167.7 | In-house | 10-291 (318) | alignment | ||
Range on Protein: 189-463
Range on HMM: 10-291/318.0
WIRLVLQNGVAGLKKEYRDS-PNEAPEDIATS-FLGNPTRNRYRNIPCCDITRVKLTDDPH----FYIHANLVSSGPNPRRFICTQAPLNGTIEEFWKMI
.| . ..| |..|| ..|. | | ..||| || | |||||.. || || . . . .| .|||| |||.||.|.
hvrrlresGelllseeyerlsrseetvtslkslepvnkaknryanilaydhtrvkLqmlegeegsDyinanyidGyrrkkayiaaqaPlpetieDfWrmv
IVTGIEYIVMLCELVEKGKPKSAEYFPSQigQTTKIGRLcTVTKESRVDIDKtLVMSTMRISKPGDNAvVKIVKHIHWRNWPDHGVPDNFLSPFRLLTVV
. |||| ...|.|| | . |.||. .....|.| .|. ...|.... .|. ...... . .. ...|. |. .|||.|||.. | |. |
WeqnsavivmltqeeergkakvhryWPsk..gsrsygkl.vvelkeevelsd.yvlrefkvtrteeee.srqvrqyhytsWpdegvpesgaslldlvrqv
KNCT-----KPIVVHCSAGVGRTGTLALILIILESICLPDFIGVPRLLAKLREERFRAVQTEMQYLYAHRCVLEYLAL-KKYVQSRE
.. .||||||||||||||. . |.|| | . | .|||.| |||| || . . .||.|| ...|....
skaqqksgagpivvhCsaGvGrtGvfiavdillerikaealvDvfqtvkqlreqrnlmvqtedqyefiydvllealasgdtevdasd
|
|||||||||
| 0043336 | (Phosphotyrosine protein) phosphatases II | 190-453 | 9.9e-70 | 230.5 | In-house | 11-277 (278) | alignment | ||
Range on Protein: 190-453
Range on HMM: 11-277/278.0
IRLVLQNGVAGLKKEYRDSPNEAPEDIA-TSFLGNPTRNRYRNIPCCDITRVKLTDDP----HFYIHANLVSSGPNPRRFICTQAPLNGTIEEFWKMIIV
.. .| |. ..|..|. . .. .... . .. | ..|||..|...| .||||.... . ||.|..|. . ||.||.||.||..|.| ||.|.
llelllnlktllllefeellsfkldtysiallpenkdknrykdilpydhsrvklsllggdldsdYinAsyvdgynvprkfiatqgPlpetvedFwrmvwe
TGIEYIVMLCELVEKGKPKSAEYFPsqiGQTTKIGRLCTVTKESRVdiDKTLVMSTMRISKPGDNAVvKIVKHIHWRNWPDHGVPDNFLSPFRLLTVVKN
|.. ||||.||||.|..|.|.|.| |.....|.. ... . ... .. |..... ||. . ..| |.|. .|||||||... . ...| .|..
lgvttivmLtelvelgrvkcaqYwp...ggsltygdftvtllkeeh..lddytvrtlevtnlgdges.rtvthyhylgwpdhgvpeslsllldflkavre
----CTKPIVVHCSAGVGRTGTLALILIILESICLPDFIGVPRLLAKLREERFRAVQTEMQYLYAHRCVLEYL
. .|..||||||||||||.......|| . .. .. ...||| |. ||||..|| . ....||||
aledsngpvlVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqRpgavqtpsqyrflyealleyl
|
|||||||||
| subfamily_PTPN9_pd | Subfamily PTPN9 | 190-455 | 7.9e-44 | 144.9 | In-house | 7-292 (297) | alignment | ||
Range on Protein: 190-455
Range on HMM: 7-292/297.0
IRLVLQNGVAGLKKEYRDSPNEAPEDIAT--SFLGNPTRNRYRNIPCCDITRVKLT----DDPHFYIHANLVSSGPNPRRFICTQAPLNGTIEEFWKMII
. | ..| ||.||| . ||..| .. .| ..||| .. | | |||.|. |. ||.|| | ... || || ||. |...||.|.
vayvkekgkrGlskeyaeirnepveGtflasklranleknrytdvlcydetrvvlakvdedeasdyinanfvdGykqkkafiatqGplkktvsdfWrmvW
VTGIEYIVMLCELVEKGKPKSAEYFPSQIGQTTKIGRLCTVTKESRVdiDKTLVMSTMRISKPGDNAvVKIVKHIHWRNWPDHGVPDNFLSPFRLLTVVK
. ||| .||.|. | ..|.|.. ..... | | . | .. . ..... |.. .. . | | |||.|||.. | . .| .|.
eqevlvivmttrvvergrlkcgqyWpleeessaefgdlsvsnvevee..eedykvrvleiknvktee.srkvthfqflsWPdyGvPssaaslldvlekvr
NC-----------------TKPIVVHCSAGVGRTGTLALILIILESICLPDFIGVPRLLAKLREERFRAVQTEMQYLYAHRCVLEYLAL
. |||||||||.|||||.. . | |. . . . | . .||. | ..||. || . . .||||
ekqalavkelgdewkghpsgPPivvhcsaGiGrtGtfitldiclsrleevgtvdvvetvkllrtqrafsiqtpeqyefcylavleyale
|
|||||||||
| subfamily_PTPRK_pd | Subfamily PTPRK | 192-452 | 1.4e-41 | 137.4 | In-house | 15-277 (314) | alignment | ||
Range on Protein: 192-452
Range on HMM: 15-277/314.0
LVLQNGVAGLKKEYRDSPNEapEDIATSfLGNPTRNRYRNIPCCDITRVKLT---DD-PHFYIHANLVSSGPNPRRFICTQAPLNGTIEEFWKMIIVTGI
|. .. |.|.|| .. | | | ..||. .| | .||.|. .| || |.|. | .|. || || ||. |...||... .
llkraegygfkeeyeslfeg..wdaakk.denreknrsgdilaydrsrvflitidgdpssdyinaalidsykrpaafivtqgPlqetvkdfWrlvydenc
EYIVMLCELVEKGKPKSAEYFPSQIGQTTKIgRLCTVtkesRVDIDKTLVMSTMRISK-PGDNAVVKIVKHIHWRNWPDHGVPDNFLSPFRLLTVVKNCT
|||| ||||.|. | .|.| . . .| .. | ...... ||. ..|..| ...|..... .||||.|| . . ..|. ||. .
asivmltelvevgrvkClkyWPedtevygdi.kvelv....etellaelvvrifrveklargqeeirevrqfqflgWpdhdvPvsatgllklvrrvkksq
K----PIVVHCSAGVGRTGTLALILIILESICLPDFIGVPRLLAKLREERFRAVQTEMQYLYAHRCVLE-Y
. .|||||||| ||||| | |.|. | . . | .||... |.|| || . . .||
eeeaGrivvhCsaGaGrtGtfiaidivldmieregvvdvfnavktlrsrkvnmveteeqykfiydvileac
|
|||||||||
| subfamily_PTPRD_pd | Subfamily PTPRD | 194-458 | 1.4e-59 | 197.2 | In-house | 18-286 (564) | alignment | ||
Range on Protein: 194-458
Range on HMM: 18-286/564.0
LQNGVAGLKKEYRDSPNEAPEDIATS-FLGNPTRNRYRNIPCCDITRVKLT----DDPHFYIHANLVSSGPNPRRFICTQAPLNGTIEEFWKMIIVTGIE
.|. . ...||.. .. . . .. | .||| || | .||.|. |. || |. . . ... .| ||.||. |||.||.|. ..
kansdlkfeeeykkieegqqftweaankpaNkaKNRyanivaYdhsRVvLskvegdegsDYINAsfidgyrkrkayIAtqgPlaetiedFWRmvweqnss
YIVMLCELVEKGKPKSAEYFPSQiGqTTKIGRLcTVTKESRVDIDkTLVMSTMRIsKPGDNAVVKIVKHIHWRNWPDHGVPDNFLSPFRLLTVVKNC---
|||| .|.|||| | ..|.|.. | |...|.| ||| |. ... . .. |... | .. .. |.. |. .|||||||.. | .|.. |...
tiVmltkleEkgkvkchkYWPek.g.tetygel.tVtleeeeela.dyeirtfkl.kkkkssesreVrqFhFtsWPdhgvpesatslLdlirkvralnep
-TKPIVVHCSAGVGRTGTLALILIILESICLPDFIGVPRLLAKLREERFRAVQTEMQYLYAHRCVLEYLALKKY
..||||||||||||||| | ..|| | . . . ...||..| |||| || . |. .||.|| .
dagPivVhCSaGVGRTGtfividamlerikeektvDiyqyvkalrkqRnamVqteeQYiFiheailealacgnt
|
|||||||||
| subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 194-456 | 2e-50 | 166.7 | In-house | 18-286 (319) | alignment | ||
Range on Protein: 194-456
Range on HMM: 18-286/319.0
LQNGVAGLKKEYRDSPNEAPEDIATS-FLGNPTRNRYRNIPCCDITRVKLTDDPH----FYIHANLVSSGPNPRRFICTQAPLNGTIEEFWKMIIVTGIE
..| .|.||... . .... .. | ..|||.|| .| |||.|.. . || |. . . . ..|| |||||. |||.||.|. ..
astgetllekefkllkeavndtfdsaskeenkkknryqnilaydrtrvvlseldgvegsdyinasfidgyqerekfiatqaPlentiedfWrmvWeeess
YIVMLCELVEKGKPKSAEYFPSQigQTTKIGRLcTVTKESRVDIDkTLVMSTMRISKPGDNAVVKIVKHIHWRNWPDHGVPDNFLSPFRLLTVVKNCT--
.|||..||||.| | .|.|.. . .. ||| .|| |.. . .... . . | .. . ||| .. .||||.||.. .| || ... .
ivvmltklveklkvklkkywpee..nfeeyGrl.ivtleeeeele.dyiirklklnkkssevetRevkhfqyteWpdhdvPekatslldllkrirksrek
---KPIVVHCSAGVGRTGTLALILIILESICLPDFIGVPRLLAKLREERFRAVQTEMQYLYAHRCVLEYLALK
.||||||||||||||| . ..|| . . . | .|| | ||.. || . . .||..
tqsgPivvhCsaGvGRtGtfivldamlervkeegvlDvfstvsrlRtqRnimvqrpeqYkfiyealleaveag
|
|||||||||
| subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 194-455 | 7.9e-48 | 158.0 | In-house | 10-278 (281) | alignment | ||
Range on Protein: 194-455
Range on HMM: 10-278/281.0
LQNGVAGLKKEYRDSPNEAPE--DIATSFLGNPTRNRYRNIPCCDITRVKLTDDPH----FYIHANLVSSGPNPRRFICTQAPLNGTIEEFWKMIIVTGI
|| ||...||.. . . |. | ..|||.|| | ||||.|.. . || || |.. .....| ||.|. ....||.|.. . .
sqndnaGfieeyeklaaigvdntataskadenvlknrYsnivaYDatrvkvtpneenkntDYinanfvpgykgekeyiatqgPvPaslvafWqmvweqkv
EYIVMLCELVEKGKPKSAEYFPSQIgQTTKIGRLcTVTKESRVdIDKTLVMSTMRISKPGDNAvvKIVKHIHWRNWPDHGVPDNFLSPFRLLTVV-----
. |||. . .|.|| | |.| . ...|.| . ||..... .| . ...... . .. . |..... .|||||||.. . . |
saivmvtreieagklkChrYWPddn.selkygdv.tvkstaee.ekatyierkfkleresget..reveqlaytaWPdhGvPattkellefrkevlklte
KNCTKPIVVHCSAGVGRTGTLALILIILESICL-PDFIGVPRLLAKLREERFRAVQTEMQYLYAHRCVLEYLAL
|. |.|.||||||||||| . ..... . | ..|.||.|| ||| .|| . .. ||..|
kktkaplvihCsaGvGrtGtyialDrlvkaveaeleeldvkavvaelrkernlmvqtvvqyefvykavldaldk
|
|||||||||
| 0036941 | (Phosphotyrosine protein) phosphatases II | 196-465 | 1.2e-79 | 263.1 | In-house | 10-289 (297) | alignment | ||
Range on Protein: 196-465
Range on HMM: 10-289/297.0
NGVAGLKKEYRDSPNEAP--EDIATSFLGNPTRNRYRNIPCCDITRVKLTDDPHFYIHANLVSSGPNPRRFICTQAPLNGTIEEFWKMIIVTGIEYIVML
.. |.|.||... .. . . ......| ..|||..|...| |||||.|... ||.|..|. .|.||.||.||..|.|.||.|. ... ||||
lflalllkefeellpllllgslsvallpenleknRykdilpydhtRVklddegsdYinAsyvdgydlkrkfIatqgPlpntvedFWrmvweqnvtvIvml
CELVEKGKPKSAEYFPSQIGQTTKIGRLCTVTKESRVDIDKTLVMSTMRISKPGDNaVVKIVKHIHWRNWPDHGVPDNFLSPFRLLTVVKN------CTK
.||||.|..| |.|.|. .|.. . |.. ... |..... .. |..... |.. ...|.|.|. .|||||||... | .... |.. .
telvelgrekcaqywpleegesltygdftvtllsvevvllddytlrtlevtdtgng.esrtvthfhytgwpdhgvpespaslldfielvrkvlkllpsgg
PIVVHCSAGVGRTGTLALILIILESIC---LPDFIGVPRLLAKLREERFRAVQTEMQYLYAHRCVLEYLALKKYVQSREDF
|..|||||||||.||.... ..|. .. . .. .. |||| |. ||||..||.. ....||.| |... . ..
pvlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyeallellkkkltkepllkl
|
|||||||||
| 0050432 | (Phosphotyrosine protein) phosphatases II | 196-457 | 3e-78 | 258.6 | In-house | 39-303 (308) | alignment | ||
Range on Protein: 196-457
Range on HMM: 39-303/308.0
NGVAGLKKEYRDSPNEAP--EDIATSFLGNPTRNRYRNIPCCDITRVKLtDDPHFYIHANLVSSG--PNPRRFICTQAPLNGTIEEFWKMIIVTGIEYIV
.. .|..|... .. | | .... | ..|||..|...| .|||| |... ||.|..|. .||.||.||.||..|.| ||.|. ....||
ldlglleeefeellsvkplleysvallpenkdkNrykdilpydhsRVkl.degsdYInAsyvdgyssklprkfIatqgPlpntvedFwrmvweqnvrvIv
MLCELVEKGKPKSAEYFPSQIG-QTTKIGRLCTVTKESRVdiDKTLVMSTMRISKPGDNAVvKIVKHIHWRNWPDHGVPDNFLSPFRLLTVVKNC--TKP
||..|||.|..| |.|.|. .| .....|... ... | ... .. |..... ||. . ..|.|.|. ||||||||... . ...| |... .|
mLtklvengrekcaqYwplelgggsleygkftvtllseev..lddytvrtleltnlgdges.rtvthfhytnWpdhgvPpspeilldflelvrkslpggp
IVVHCSAGVGRTGTLALILIILESICLPDFIGVPRLLAKLREERFRAVQTEMQYLYAHRCVLEYLALKK
||||||||||||||.......|| . . |. ...|||| | .|||..|||. .|..|||| ||.
ivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkklReqRpgmvqtpeqylflyralleylklkl
|
|||||||||
| 0047943 | (Phosphotyrosine protein) phosphatases II | 196-453 | 6.7e-74 | 244.1 | In-house | 9-272 (273) | alignment | ||
Range on Protein: 196-453
Range on HMM: 9-272/273.0
NGVAGLKKEYRDSPNEAPED--IATSFLGNPTRNRYRNIPCCDITRVKLTDDPHFYIHANLVSSGPNPRRFICTQAPLNGTIEEFWKMIIVTGIEYIVML
.|...|..|... .. |. .... | ..|||..|...| .||||.|... ||.|..|. . .|.||.||.||..|.|.||.|. ....||||
lgltllleefelllslkplltysvallpenkdknrykdilpydhsrvklgdggsdyinAsyvdgynlkrkfiatqgPlpntvedfwrmvweqnvrviVmL
CELVEKGKPKSAEYFPSQIGQ-TTKIGRLCTVTKESRVdiDKTLVMSTMRISKPGDNAvVKIVKHIHWRNWPDHGVPDNFLSPFRLLTVVKN------CT
.||||.|..| | |.|. |. ... |... ... . ... .. |..... |.. ...|.|.|. .|||||||... | .... .|..
telvelgrekcaqYwpleggelsltygkftvtllseet..kddytvrtleltnlgtge.srtvthfhytgwpdhgvppslesllefielvrkalealpsn
KPIVVHCSAGVGRTGTLALILIILESICLPDFIGVPRLLAKLREERFRAVQTEMQYLYAHRCVLEYL
.|.|||||||||||||.......|. . . |. ....||. |. .|||. ||.. ....||||
gpvvVHCsaGvgRtgtfialdllldqlekeggvdvleavkllrsqRpgmvqtpeqyrflyealleyl
|
|||||||||
| subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 196-451 | 1.1e-52 | 173.9 | In-house | 18-277 (288) | alignment | ||
Range on Protein: 196-451
Range on HMM: 18-277/288.0
NGVAGLKKEYRDSP--NEAPEDIATSFLGNPTRNRYRNIPCCDITRVKLTD----DPHFYIHANLVSSGPNPRRFICTQAPLNGTIEEFWKMIIVTGIEY
.. .|...||. . .. .. |.. | ..|||||| | .||||.. . || |. . . . ...|.||.|| |...||... . ..
rnrtgfseeynsLaalektksvtagrlavnakknRyrnilpyDekrvklkkleeeagaDYinasyidgekkkkkyiatqgPladtvndfWelvyenktst
IVMLCELVEKGKPKSAEYFPSQiGQTTKIGRLcTVTKESRVDIDKTlVMSTMRISKPGDNavvKIVKHIHWRNWPDHGVPDNFLSPFRLLTVVKNC----
|||| ||||.|| | ||.|.. .. .. | . ||| . . ... |. .. . | ... ... .. |||||||.. . ||. ||.
ivmltelveggktkCeeYWPda.dkpknyGsv.tvtlveskeledf.vlrklllekkkte...leitqyqylaWpdhgvPeskapllellrqvkvanqad
TKPIVVHCSAGVGRTGTLALILIILESICLPDFIGVPRLLAKLREERFRAVQTEMQYLYAHRCVLE
|.||.|||||||||||| . ... . |.| | .||||..|. |||. || . ....|.
tgpiivhCsaGvGrtgtFialdalidaveeedyiDvagtvaklRkqRallvqtlkqYefiyevlls
|
|||||||||
| subfamily_PTPRG_pd | Subfamily PTPRG | 196-461 | 3.5e-42 | 139.4 | In-house | 16-295 (563) | alignment | ||
Range on Protein: 196-461
Range on HMM: 16-295/563.0
NGVAGLKKEYRDSPNEA-PEDIATSF---LGNPTRNRYRNIPCCDITRVKLTDDPH-----FYIHANLVSSGPNPRRFICTQAPLNGTIEEFWKMIIVTG
.| |...|. . .| ..|. ... | .||| || | .||||.. | || || . . || || ||. |.. ||.||
dgdigfseefealqsetiskdldaehsqkpenkrKnRylnivaydrsRvklsplpgkkkklDYinAnyidGyqkskafiatqgplkdtfddFWrmiWeqn
IEYIVMLCELVEKGKPKSAEYFPSqiGQTTKIGRLCTVTKESR---VDIDKTLVMSTMRISKPGDNAVVKIVKHIHWRNWPDHGVPDNFLspFRLLTVVK
. |||. .|||.|. | |.|. .. ..| | .|. . .|||. ... | . .| |.. |. .|||||||. | . | |.|
vaiivmitnlvergrrkcdvYWPk..desetygalqvtlieeevlalytvrtlviknlklkkkkqcdteklvrqyhytkWPdhgvPehsl..pvLifvkk
NC------TKPIVVHCSAGVGRTGTLALILIILESICLPDFIGVPRLLAKLREERFRAVQTEMQYLYAHRCVLEYLALKKYVQS
. . |||||||||||||||. . .|. | . . | ..| ..| .| |||| ||.. | .|| .| |. .
ssaankaeaGPivvHcsaGvgrtGtyivldtllkqiqqenavnvfgflkhiraqRnflvqteEqYiflhdalleaiasketell
|
|||||||||
| subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 196-468 | 4.5e-38 | 126.3 | In-house | 31-306 (319) | alignment | ||
Range on Protein: 196-468
Range on HMM: 31-306/319.0
NGVAGLKKEYRDSPNEAPEDIATSFL---GNPTRNRYRNIPCCDITRVKLTD----DPHFYIHANLVSSGPNPRRFICTQAPLNGTIEEFWKMIIVTGIE
. . |. |.| .. ... .| | .||. || | ..||| . || | |. .. ..| .| ||. |...||.|| .
ddltklevefrracklgvnladqtfanldqnkdknriinilafdknvvklerliGeefsdyinasfvtGyqrkdkyiaaqGPldntladfWrmiweyncs
YIVMLCelvekgKPKSAEYFPSQIGQTTKIGRLCTvtkeSRVDIDKTLVMSTMRISKPGDNAVVKIVKHIHWRNWPDHGVPDNFLSPFRLLTV------V
||.| | | ..|.| .| .. . . . . |. . |. ...|. | . .. .. |.. |||.|||| .||.
tivllt......kdkcsqywplkivikeerfkvkv....dsveetaeyvvrdielsedgkekdirkitqfhflGwpdvGvpdypsdlmrlvkkvrhltsk
KNCTKPIVVHCSAGVGRTGTLALILIILESICLPDFIGVPRLLAKLREERFRAVQTEMQYLYAHRCVLEYLALKKYVQSREDFAKF
.| ..|||||||||||||. . ..|. . . . | ... ||..| . || .|| . . .|| . . . || .
enhranivvhcsaGvGrtGvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysalleehlfghsdvampdfpay
|
|||||||||
| subfamily_Cele-PTP-4_pd | Subfamily Cele-PTP-4 | 198-459 | 2.8e-25 | 83.4 | In-house | 25-289 (302) | alignment | ||
Range on Protein: 198-459
Range on HMM: 25-289/302.0
VAGLKKEYRDSPNE-APEDIATSFLGNPTRNRYRNIPCCDITRVKLTDDPHFYIHANLVSSGPNPRRFICTQAPLNGTI---EEFWKMIIVTGIEYIVML
| .|||. . .. . ..| |. .|. ..|. | ..|||. | .|..| |. | | .| | .. ||||.|. | .|.|
taevkkefkkidtmkvdlekCkafkknlkknqsedvpildsnlvkleaepdsyvnaskvevPeltrsiilaQlpkvdsedsveeFWrmvfqekivsvvil
CELVEKGKpKSAEYFPSQIGQTTKIGRLCTVTKESRVDIDKTlVMSTMRI-SKPGDNAVVKIVKHIHwrNWPDHGVPDNFLSPFRLLTVV----KNCTKP
| | |.|| . |. .. |.. .. ... . .. . . |.|. |.... ||... ||... . . . | .....
vgeeelkk.tlselfpkksgdykeygkmfvNnrkVekaeeek.tryviEvlPegcsnsvlanvyvlt..nWkqkkvpvkyaeliktaakvfakkikaden
IVVHCSAGVGRTGTLALILIILESICLPDFIGVPRLLAKLREERFRAVQTEMQYLYAHRCVLEYLalKKYV
.|. |.|| |.. . .|.. . . .....|..| |||.. || ....| |. || |
tvivSknGaGRagafltlavaveklqkgkepnikeivksiRsqRpravdslkQyvslyialllyi..kkkv
|
|||||||||
| subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 199-453 | 2.2e-38 | 127.0 | In-house | 24-279 (315) | alignment | ||
Range on Protein: 199-453
Range on HMM: 24-279/315.0
AGLKKEYRDSPNE--APEDIATSfLGNPTRNRYRNIPCCDITRVKL---TDDPH-FYIHANLVSSGPNPRRFICTQAPLNGTIEEFWKMIIVTGIEYIVM
|.|..| | | |.| | .||| || | .||.| ||| |. ||.. .||.|..|.|. ....||... | |||
ngfkqdyesipggqlhpldvakk.ienkqknryiniiaydksrvqlpllendphsdyvnanfidGynkkrryiaaqgpnvasvkdfwrlvfeedigkivm
LCELVEKGKPKSAEYFPSQigqTTKIGRLcTVTKESRVDIDKtLVMSTMRISKpGDNavVKIVKHIHWRNWPDHGVPDNFLSPFRLLTVVK----NCTKP
| .|||. | |. .|.| . |.. |||. | .. . . |. . ||| .. | .|. ||| ||| .. | || | .
ltnlvegekrkaekywpdk...kviyGki.tvtrkseevnte.ytvrtlsvvf.gdn..irevvqlhytswpdmgvpkytiplmnlirtvkqhhtnsvga
IVVHCSAGVGRTGTLALILIILESICLPDFIGVPRLLAKLREERFRAVQTEMQYLYAHRCVLEYL
||||||||||||||. . .|. . . | | ... ..|. | ..||. || . . .|| .
ivvhcsaGvGrtGtfitldavldqaeaenaidvynfitgvrqnrikmvqvaeqyqfiydalletf
|
|||||||||
| subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 200-454 | 1.5e-49 | 163.9 | In-house | 28-291 (298) | alignment | ||
Range on Protein: 200-454
Range on HMM: 28-291/298.0
GLKKEYRDSPNEAP-----EDIATSFLGNPTRNRYRNIPCCDITRVKLTD----DPHFYIHANLVSSGPNPRRFICTQAPLNGTIEEFWKMIIVTGIEYI
|...|.. . | ... | .||| .| | .|| |.. . || | ... . || |||||. |.|.||.|.. |. |
gyalefqrlnsvsseieeeekevarkpenkkkNRyadiialdssRvvLekedadeesdYiNAsflhaykgrnafiatqaPltetvedFWrmvteedigti
VMLCELVEKGKPKSAEYFPSQigQTTKIGRLcTVTKESRVDiDKTLVMSTMRISKPGDNaVVKIVKHIHWRNWPDHGVPDNFLSPFRLLTVVKN----CT
||| .|.|..| | .|.|.. .... |.. ||. |. . |.. .. .|| . . |...|. .|||.||| | | . ||. |. .
VmltnleeldktkyhkywPde..gketygei.tvsllskee.fadlivrklkvskkkee.kerevrqlhftsWpdkgvpenatsvldllrkvrasqqqag
-KPIVVHCSAGVGRTGTLALILIILESICLPDFIGVPRLLAKLREERFRAVQTEMQYLYAHRCVLEYLA
||..|.|||||||.|| | .|| . . | . . ||..| ||||| || . . |||.|.
nkpvivqCsaGvgRsGtfiaidsvlervkkeqvvDvfqvvkvlRkkrpgavqteeqYvfiyeavleald
|
|||||||||
| subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 200-454 | 4e-47 | 155.9 | In-house | 23-284 (305) | alignment | ||
Range on Protein: 200-454
Range on HMM: 23-284/305.0
GLKKEYRDSPNE-APEDIATSfLGNPTRNRYRNIPCCDITRVKLTDDPHF----YIHANLVSSGPNPRRFICTQAPLNGTIEEFWKMIIVTGIEYIVMLC
||...|. ..| . |. .. | ..||...| | |..|| ... || |. | . . ..| .|.||. |...||..|. . .. ||||.
gleaqykslyeeeesidvgkk.eankaknrlkeitlldddriiltekeslddsdyinasyvdgykrkkkyivaqgPlkntvadfWrliveekvstivmlt
ELVEKGKPKSAEYFPSQIGQTTKIGRLcTVTKESRVDIdKTLVMSTMRISKPGDNAVVKIVKHIHWRNWPDHGVPDNFLSPFRLLTVVKNCT-----KPI
.||| || | |.| ........|.. .|. .|. . . ... ..||. .. . | . . .|||||||. | .|. |.. .|.
klveggkdkCrqYWpesktekkefgef.svelksekta.sdyieRklkisiededkesrtvlqyqltdWPdhGvpqfatsllslikrvqkdqkkdkgvpl
VVHCSAGVGRTGTLALILIILESICLPDFIGVPRLLAKLREERFRAVQTEMQYLYAHRCVLEYLA
.|||||||||||. . | || . . . | ..| .||..| .||| || . | . |..
lVhCsagvgRtGvfiavdialerlkkEevvdvfevlkqlRskrmkmvqtldqYvflhdaldelit
|
|||||||||
| subfamily_Cele-PTP-13_pd | Subfamily Cele-PTP-13 | 200-457 | 4.6e-44 | 145.2 | In-house | 12-273 (281) | alignment | ||
Range on Protein: 200-457
Range on HMM: 12-273/281.0
GLKKEYRDSPNEAPEDIATSFL--GNPTRNRYRNIPCCDITRVKLTD-----DPHFYIHANLVSSGPNPRRFICTQAPLNGTIEEFWKMIIVTGIEYIVM
.|.|. . | . | |..| | | .||| |||| ||.||.| . ||||| . | | .| || | . | .||.|| |||
dfkqefsnlpgdppsdlctvfnqpvnnkknrylnipcldisrvqlkvkmpnknstdyihanyirspflkrgyiltqgpkketradfwrmiwqenttaivm
LCELVEKGKPKSAEYFPSQIGQTTKIGRLCTVTKESRVdiDKTLVMSTMRISKPGDNavvKIVKHIHWRNWPDHGVPDNFLSPFRLLTVVKNCTKPIVVH
||...| . | ||||| . .. .| ..| | .|.|| . . .| |. ... | |..||| ||. ...| .. . | |.|
lcqfletnrekcaeyfprnahcclqfdklsvsyedstv..nkslvttrlnlsyeget...rlithwlwkewpdwqvpessevmlkilrkirarstppvih
CSAGVGRTGTLALILIILESIC----LPDfigVPRLLAKLRE-ERFRAVQTEMQYLYAHRCVLEYLALKK
|||||||.||| . | |.|| ||| . .....|| | .||| ||. . .|.. |
csagvgrsgtlmaveialqsihshftlpd...ikqivshlrvtgraasvqtlqqymliwkvlldfgvayk
|
|||||||||
| subfamily_Ptp69D_pd | Subfamily Ptp69D | 200-473 | 3.9e-42 | 139.4 | In-house | 23-303 (307) | alignment | ||
Range on Protein: 200-473
Range on HMM: 23-303/307.0
GLKKEYRDSP-NEAPEDIATSF-LGNPTRNRYRNIPCCDITRVKLT----DDPHFYIHANLVSSGPNPRRFICTQAPLNGTIEEFWKMIIVTGIEYIVML
||.|||. . .| . . .| | .||| .| | |||||. .. || |. . . . ..||. |.|...||..||.|| .. ||||
glakeyekLeareidkstkvsekkenalknRyedikafDktRvkLkkingkedsdYinasfikgykekkkfiaaqdPveatigDfWRmiaeqevtlivml
CELVEKGKPKSAEYFP-SQIGQTTKIGRLCTVTKESRVDIDKTLVMSTMRISKPGDNAVVKIVKHiHWRNWPDHGVPDNFLSPFRLLTVV----KNCTKP
.| || . | | |.| .. | .| . ... | ..| .|.. . . .. |.|.. |. .|.| ||. . ..|.. | |. |
snlteknrkkcakYWpiedevqygdilvklvseekhsdyiiReldvskkkeesgevedsrkvvqy.hytgWkDskvPevargllklieqvrelyklnrsP
IVVHCSAGVGRTGTLALILIILESICLPDFIGVPRLLAKLREERFRAVQTEMQYLYAHRCVLEYLAlkkYVQSREDFAKFAKDYE
|||||||||||.|.. . ..|. . . | . . .||..| || || . .| .|.| | .. || .... .|
ivvhCsaGvgrsgifvaldsllqqlkaedkvdifetvkdLrsqRnllvqsleqYvflyralldyss...ygdtdedvddledaie
|
|||||||||
| subfamily_PTPN5_RR_pd | Subfamily PTPN5_RR | 200-454 | 2e-41 | 136.9 | In-house | 6-269 (274) | alignment | ||
Range on Protein: 200-454
Range on HMM: 6-269/274.0
GLKKEYRDSPNEApEDIATSFLGNPTRNRYRNIPCCDITRVKL-----TDDPHFYIHANLVSS-GPNPRRFICTQAPLNGTIEEFWKMIIVTGIEYIVML
|.||. . | . . .. |. |.|||..| . .|| | .|. || || . . . . .. || || |...||.|| . .. ||||
dlekeflelPlnf.dqeeldvfgsqtknryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntvadfWrmiyqeevqvivml
CELVEKGKPKSAEYFPSQIGQ--TTKIGRlCTVTKESRVDIDKTLVmSTMRISKPGDnavVKIVKHIHWRNWPDHGVPDNFLSPFRLLTVVKNC------
.| |. . | |.||| ... . . | .. |. |. .. | .. ... . . |||. . .|||| .||. . ..|.. |..
tklkeaneqkCavyfPdaedyeiserygd.veikvekiverndysv.rklvlkyler...ersvkhywytdWPdhksPddantlldlvleveesreeena
-TKPIVVHCSAGVGRTGTLALILIILESICLPDFIGVPRLLAKLREERFRAVQTEMQYLYAHRCVLEYLA
. |.|||||||.|||| |.| . . .. | .. ..|| .| |||. || . || . .||
klapvvvhCsaGiGrtGcfiaisiavrqlreeivvdvlkivcnlrldrGGmvqtseqyelihralclylk
|
|||||||||
| 0046845 | (Phosphotyrosine protein) phosphatases II | 201-457 | 2.3e-73 | 242.4 | In-house | 2-278 (284) | alignment | ||
Range on Protein: 201-457
Range on HMM: 2-278/284.0
LKKEYRDSPNEAPE----DIATSFLGNPTRNRYRNIPCCDITRVKLTD-----DPHFYIHANLVSSG-----PNPRRFICTQAPLNGTIEEFWKMIIVTG
|..|.. .. . .. .. | ..|||..|.. | .||||. . . ||.|..|. ....||.||.||..|.|.||.|. .
leeefeellsltvklllslsvallpenlsknRykdilpydhsRVklksldgdledsdYinAsyvdgydldltyikkkfIatqgPlpntvedFwrmvweqn
IEYIVMLCELVEKGKPKSAEYFPSQiGQTTKIGRLCTVTKESRVdiDKTLVMSTMRISKPGDNAVVKIVKHIHWRNWPDHGVPDNFLSPFRLLTVVKNC-
...||||.||||.|. | | |.|. |.. ..|... ... | ... .. |..... | . ...|.|.|. .|||||||... . ...| |...
vrvIVmltelvengrekcaqYwple.gevltygdftvtllseev..kddytvrtleltnlgytgesrtvthfhytswpdhgvppspedlleflrlvrell
-----TKPIVVHCSAGVGRTGTLALILIILESICLPD---FIGVPRLLAKLREERFRAVQTEMQYLYAHRCVLEYLALKK
.|||||||||||||||.... ..|| . . . |. ....||| |. .|||..||.. ....|||| ||.
enlpgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvqtleqyrfvyealleylklkl
|
|||||||||
| subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 201-457 | 3.9e-43 | 142.3 | In-house | 20-280 (515) | alignment | ||
Range on Protein: 201-457
Range on HMM: 20-280/515.0
LKKEYRD--SPNEAPEDIATSFLgNPTRNRYRNIPCCDITRVKL---TDDPHF-YIHANLVSSGPNPRRFICTQAPLNGTIEEFWKMIIVTGIEYIVMLC
. .|..| || |. .| . | ..|||.|| | .|||| |.|| |. | . | | . .|..|.|.. ....||.... . |.|.
fseefhdlpgpniypqtvaqeei.nfkknryknilPydsvrvklevindnPhsdyfnasyipsfdndkayiasqgPnkasvddfWrlvlqenvttiamvt
ELVEKGKPKSAEYFPSQIGQTTKIGRLCTVTKeSrVDIDKTLVMSTMRISKPGDnavVKIVKHIHWRNWPDHGVPDNFLSPFRLLTVVKN----CTKPIV
.| | | | ..|.| . |.. | | . . | .. . . .... | | .. | |. .|||.||| . | ..|. || | |..
klkegdkikcgkyWPdkpgdsvkfGsikvelv.s.leactggikrkltvlkgdd...srtvtqfhfteWPdkGvpkhtssllklikevkadhgqythpli
VHCSAGVGRTGTLALILIILESICLPDFIGVPRLLAKLREERFRAVQTEMQYLYAHRCVLEYLALKK
.|||||||||| . | .. . . . | ... ..|..| |||. || . . |||.| ..
ihcsaGvGrtGvvisidsvvahakttrmvdvfnfvtnirqkrpylvqtqeqyafiygavledllwrn
|
|||||||||
| subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 202-467 | 2.8e-42 | 139.7 | In-house | 22-291 (315) | alignment | ||
Range on Protein: 202-467
Range on HMM: 22-291/315.0
KKEYRDSPNEAPED-IATSFLGNPTRNRYRNIPCCDITRVKL---TDDPH-FYIHANLVSSGPNPRRFICTQAPLNGTIEEFWKMIIVTGIEYIVMLCEL
.|..| |. . .. | ..|||.|| | .|||| |.|. || | . | . . .|..|.||. ....||.|.. . . |||. ..
seefhdlpdPdiyrqrvaretinfkknryknilPldsarvkleviddsPdsdyinasyiksvdddkayiasqgPlkasvddfwrmvlqekvttivmvtkk
VEKGKPKSAEYFPSQIGQTTKIGRLCTVTKESRVDIDKTlvMSTMrISKPGDNavVKIVKHIHWRNWPDHGVPDNFLSPFRLLTVVKN----CTKPIVVH
| | | . |.| . ..... | . . . | | . . . . . ... . | ....|||.||. . | ..|. || . ...||
qegdkikcrqywPdrkadsvefGsikvellsleadtdgv..arkl.vtrksee..srtvtqfqftewPdkGvdkqtssllklikevkadngkkefsllvh
CSAGVGRTGTLALILIILESICLPDFIGVPRLLAKLREERFRAVQTEMQYLYAHRCVLEYLALKKYVQSREDFAK
||||||||| . | ... | . . | ... .||..| |||| .| . . |||.| .. . |.
csaGvGrtGvvisidevvaqikrtrsvdvfnfvknlrakrpylvqteeeyafiydavledllwrntlilvihftd
|
|||||||||
| subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 202-453 | 8.4e-32 | 105.6 | In-house | 26-288 (325) | alignment | ||
Range on Protein: 202-453
Range on HMM: 26-288/325.0
KKEYRDSPNEAPEDIATS-FLGNPTRNRYRNIPCCDITRVKL---TDDPHF-YIHANLVSSGPNPRRFICTQAPLNGTIEEFWKMIIVTGIEYIVMLCEL
.|. |.. . .. | .||..|. | .|| | |||. || |. . . . |. .|||| ||...|.... .|.| ||
ahefgllpsddgiakkvamkpenkaknrfknvvaldksrvvletkkddpssdyinasylrddkkkdvflaaqaPltatindlWrlvldWrcsvvvvlnel
vEKGKPKSAEYFPSQIGQTTKIGRLcTVTKESRVDIdKTLVMSTMRISKPGDnAVVKIVKHIHWRNWPDHGVPDN---FLSPFRLLTVVKNC-------T
..|| . | |.| ..|.. . | | | . .| |. . . .. . . || ... |.| ||. ..| .|. |... .
.dlgkdrcavywpkemgksktfGgl.evklrtieei.sdyvhrvldvkqvkk.GetrsvkqfqlqswddmGvqkrpatlisilqlvkavservtantkas
KPIVVHCSAGVGRTGTLALILIILESICLPDFIGVPRLLAKLREERFRAVQTEMQYLYAHRCVLEYL
||.|||||||||||... . .|. . . . . |||..| |.| || . .. |..
tpilvhcsaGvGrtGvfislysalakvieesrvdifgfvkklrkdrpsmvetvdqyiliyealveay
|
|||||||||
| DSPc_SM00195 | 204-453 | 3.1e-71 | 235.1 | In-house | 5-262 (263) | alignment | |||
Range on Protein: 204-453
Range on HMM: 5-262/263.0
EYRDSPNEAP--EDIATSFLGNPTRNRYRNIPCCDITRVKLTDDP----HFYIHANLVSSGPNPRRFICTQAPLNGTIEEFWKMIIVTGIEYIVMLCELV
|.... .... | . . | ..|||.||...| |||||.... . ||.|| .. .....|.||.||. |.|.||.|.. .....||||.| .
efekleestspketteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivmlteee
EKGKPKSAEYFPSQIGQTTKIGrLCTVTKESRVDIDKTLVMSTMRISKPGDnAVVKIVKHIHWRNWPDHGVPDNFLSPFRLLTVVKNCTK----PIVVHC
|.|| | ..|.|...|.....| .|. . .. ... |....| |. . |......|||||||||. | ..|| .||.... ||||||
engkekcdrywpeesggketfg.kisvklvevekkkdeiilrtleltkegk.eetrkvtqyqyknWpdhgvpdstksvlellravkkskstssgpivVhC
SAGVGRTGTLALILIILESICLPDFIGVPRLLAKLREERFRAVQTEMQYLYAHRCVLEYL
|||||||||...| |||.... . . . .. .||..|...|||..|||......|||.
saGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaileyi
|
|||||||||
| PTPc_SM00194 | 204-453 | 3.1e-71 | 235.1 | In-house | 5-262 (263) | alignment | |||
Range on Protein: 204-453
Range on HMM: 5-262/263.0
EYRDSPNEAP--EDIATSFLGNPTRNRYRNIPCCDITRVKLTDDP----HFYIHANLVSSGPNPRRFICTQAPLNGTIEEFWKMIIVTGIEYIVMLCELV
|.... .... | . . | ..|||.||...| |||||.... . ||.|| .. .....|.||.||. |.|.||.|.. .....||||.| .
efekleestspketteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivmlteee
EKGKPKSAEYFPSQIGQTTKIGrLCTVTKESRVDIDKTLVMSTMRISKPGDnAVVKIVKHIHWRNWPDHGVPDNFLSPFRLLTVVKNCTK----PIVVHC
|.|| | ..|.|...|.....| .|. . .. ... |....| |. . |......|||||||||. | ..|| .||.... ||||||
engkekcdrywpeesggketfg.kisvklvevekkkdeiilrtleltkegk.eetrkvtqyqyknWpdhgvpdstksvlellravkkskstssgpivVhC
SAGVGRTGTLALILIILESICLPDFIGVPRLLAKLREERFRAVQTEMQYLYAHRCVLEYL
|||||||||...| |||.... . . . .. .||..|...|||..|||......|||.
saGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaileyi
|
|||||||||
| subfamily_Urchin-PTP-4_pd | Subfamily Urchin-PTP-4 | 204-457 | 1.3e-27 | 91.2 | In-house | 25-240 (392) | alignment | ||
Range on Protein: 204-457
Range on HMM: 25-240/392.0
EYRDSPN--EAPEDIATSfLGNPTRNRYRNIPCCDITRVKL---TDDPH-FYIHANLVSSGPNPRRFICTQAPLNGTIEEFWKMIIVTGIEYIVMLCELV
|..| |. |. .| | .|||.|| | .|||| | |. |. | . | | . .|..|.| ....||.|. . |.|. .|
efhdlpgpdiypqtvaqk.einlkknryknilpydsarvkleviddipdsdylnasyipsfdnekayiasqgpnaaslddfwrmvfqenvttiamvtklk
EKGkpksaeyfpsqigqttkigrlctvtkesrvdidktlvmstmriskPGDNavVKIVKHIHWRNWPDHGVPDNFLSPFRLLTVVK----NCTKPIVVHC
| ||. .. | |. .|||..|| | .... || . |.|...||
egd.............................................kgdd..artvaqfhftewPdkdvpkhtssllkfikevkadfGqythpliihc
SAGVGRTGTLALILIILESICLPDFIGVPRLLAKLREERFRAVQTEMQYLYAHRCVLEYLALKK
|||||||| . | .. .. | .....|..| |||. || . . .||| | ..
sagvgrtgvvisidsvvahakktrmvdvfnfvtnirrkrpymvqtkeqyafiygavledllwrn
|
|||||||||
| subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 210-455 | 1.8e-34 | 114.1 | In-house | 37-280 (287) | alignment | ||
Range on Protein: 210-455
Range on HMM: 37-280/287.0
NEAPEDIATSflgNPTRNRYRNIPCCDITRVKLTDDPHFYIHANLVSSGPNPRRFICTQAPLNGTIEEFWKMIIVTGIEYIVMLCELVEKGKPKSAEYFP
.| .||.. | .||...| | || | . . || | . . . ..|| ...|. |. .|||.| .. |||||.. |. . . .|.|
devthniasq...nkdknRltqilvpdnyrvllkgehpdyinavfidgykekkafiiaesPmfntarnfWkliddrnvtaivmlcqekendeevcyqyWp
SQigQTTKIGRLCTVTKESRvdIDKTLVMSTMRISKPGDNAVVKIVKHIHWRNWPDHG-VPDNFLSPFR----LLTVVKNCTKPIVVHCSAGVGRTGTLA
.. ... .| . . . .. .... . . .. . || . ||...| |.. . . | |. .||||||..|||....
ee..ksvvlGeyniellnee..vnagyierklevknknkagdkqqvkqyqitnWdstgkvtepqtillvieemyktqrkrgntsivvhCsdtvGrsamfc
LILIILESICLPDFIGVPRLLAKLREERFRAVQTEMQYLYAHRCVLEYLAL
. . .. | | ..| . | . .||| || . |||||
aaattinkckteGviDvfqvlksqriqkpgsvqtveqykfindivleylds
|
|||||||||
| subfamily_Cele-PTP-15_pd | Subfamily Cele-PTP-15 | 213-457 | 7.7e-39 | 128.4 | In-house | 25-274 (285) | alignment | ||
Range on Protein: 213-457
Range on HMM: 25-274/285.0
PEDIATSFLGNPTRNRYRNIPCCDITRVKLTDDPHFYIHANLVS-SGPNPRRFICTQAPLNGTIEEFWKMIIVTGIEYIVMLCELVEKGKPKSAEYFPSQ
|. |.. || ||| .. | . ||| | . . ||||. . | . .| || || |. .||.|| | |..||| |.| | | | |.| .
pnctytayeanpdlnryadvrcieetrvvlknhdrdyihaswmrmpgkdqstyittqgplpetlsdfwhmiyqekiayvlmlctlfeggvekcalyypek
IGQTTKIGRLCTVTKESRV-DIDKTLVmSTMRISKPGDN-AVVKIVKHIHWRNWPDHGVPDNFLSPFRLLTVVK---NCTKPIVVHCSAGVGRTGTLALI
.|. |.|. | . | |.. .. . . | . ..|.. |||. |.. | || |||.|||||||||| |. |
lgevvkfgkyeitlteckeeaiagtil.naltvintedasseplymnhvqvpwwpdqlapedarpmielykwvkkvnpkekpicvhcsagvgrtatfvgi
LIILESICLPDFIGVPRLLAKLREERFRAVQTEMQYLYAHRCVLEYLALKK
| | . .. ..| ||.|||. ||.|. . ..||. .
dyatirimenpniemldivremramrfqavqshmqflflyvvlmeyfigeg
|
|||||||||
| subfamily_Sponge-PTP5_pd | Subfamily Sponge-PTP5 | 213-452 | 3.1e-32 | 106.6 | In-house | 24-265 (283) | alignment | ||
Range on Protein: 213-452
Range on HMM: 24-265/283.0
PEDIATSfLGNPTRNRYRNIPCCDITRVKLTDDPHFYIHANLVS---SGPNPRRFICTQAPLNGTIEEFWKMIIVTGIEYIVMLCELVEKGKPKSAEYFP
. |||.. |.. ||...| | ||.| ... || | . | . ...| .|.||. |. .||||. | |||| .| | . | . |.|
dadiasa.denkrknrnqeivpadqwrvelksesrdyinavfipvsksykqdkkyiiaqsPldrtvvdfWkmvfdekitaivmltklqedlrikCsqyWP
SQigQTTKIGRLC-TVTKESRvDIDKTLVMSTMRISKPGDNAVVkiVKHIHWRNWPDH--GVPDNFLSPFRLLTVV--KNCTKPIVVHCSAGVGRTGTLA
.. . . | . |. || . ..| . .... . | .| . . . | | | .. .. |||||||.|.|||...
kr..GsedyGeftvtlrkett.snsfiikelllrvnssakstll..lahyqvidWleygeqaiinslvkfnkvislqteskkgPivvhCstgiGrtavfi
LILIILESICLPDFIGVPRLLAKLREERFRAVQTEMQYLYAHRCVLEY
. .. . . |. . .||.| |||| || | |||
aasasvkdaltesvvdvfavvkimreqrmmavqtldqyklvhelvleq
|
|||||||||
| subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 215-346 | 8.1e-13 | 42.8 | In-house | 38-187 (350) | alignment | ||
Range on Protein: 215-346
Range on HMM: 38-187/350.0
D-IATSFLGNPTRNRYRNIPCCDITRVKLT------------DDPHFYIHANLVSSG-----PNPR-RFICTQAPLNGTIEEFWKMIIVTGIEYIVMLCE
| | .. . ..|||.|| . .|||| . || || .. || ..| ||||| |...|.|.|. ... |..| .
DvilseGvelfaknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilslts
LVEKGKPKSAEYFPSQIGQT--TKIgrlcTVTKESRVDIDK-TLVMSTMRISKP
.|| . | .|.. . |. . ..|. ..|.. .| . ... .
dvelnlekcyrYWqegsydditvkl....askwenimgindsslysadvkkeas
|
|||||||||
| subfamily_PTPRN_pd | Subfamily PTPRN | 217-451 | 6.6e-27 | 89.0 | In-house | 50-290 (297) | alignment | ||
Range on Protein: 217-451
Range on HMM: 50-290/297.0
ATSFLGNPTRNRYRNIPCCDITRVKLTD----DPHFYIHANLV-SSGPNPRRFICTQAPLNGTIEEFWKMIIVTGIEYIVMLCELVEKGKPKSAEYFPSQ
... | ..||.... | .||||.. . ..|| | . . | .| ||.||. |. .||.|. |. ||.|..| |.| . ..|.| .
vakaeknvkknrskavlpydhsrvklkeeasaeksdyinasaildhdprapayiatqgplastvadfwqmvweqGvvvivnltrleeegvkqckrywpde
IGQTTKIGRLCTVTKesRVDIDKTLVMSTMriSKPGDNAVVKIVKHIHWRNWPDHGVPDNFLSPFRLLTVVKNC----TKPIVVHCSAGVGRTGTLALIL
.. .| . |.. . | || | | .. . | |. ||..||| . | . . | . . |||||||.|.||||. ||
Gsevyhiyevhlvse..hiwcddylvrsfy..lknlqtsetrtvtqfhflswpeegvPasaksllefrrkvnksyrGrscpivvhcsdGaGrtGvyilid
IILESICLP-DFIGVPRLLAKLREERFRAVQTEMQYLYAHRCVLE
..|. . | . | .||..| |.|. |. .| .| |
lvlnrllkGvkeidiaatlehlrdqrpglvktkdqfefaltavae
|
|||||||||
| 0040439 | (Phosphotyrosine protein) phosphatases II | 218-453 | 2.6e-65 | 215.8 | In-house | 6-246 (249) | alignment | ||
Range on Protein: 218-453
Range on HMM: 6-246/249.0
TSFLGNPTRNRYRNIPCCDITRVKLTD----DPHFYIHANLVSSGPNPRRFICTQAPLNGTIEEFWKMIIVTGIEYIVMLCELVEKGKPKSAEYFPSqiG
.... |. .|||..|...| .||||.. .. ||.|.... .||||.||.||..|.| ||.|. ||..||||..|||.|. | |.|.|. |
allpenkdknrypdilpydhsrvklsilpglflsdyinAsyidgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqywpl..g
QTTKIGRLCTVTKESRVdiDKTLVMSTMRISKPgDNAVVKIVKHIHWRNWPDHGVPDNFLSPFRLLTVVKN------CTKPIVVHCSAGVGRTGTLALIL
.....|.. ... | . ... |..... . . |.||.. .|||||||..| . .... |.. . .|..||||||||||||.....
gsleygdftvtllsvev..kddytvrtleltnl.ydgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtfiaay
IILESICLPDFIGVPRLLAKLREERFRAVQTEMQYLYAHRCVLEYL
..|| . . .. ...||. |. |||.. || . ....||.|
lmleqlekelgvdleeavkllrsqRpgavqnpeqyrflyeallell
|
|||||||||
| 0045098 | (Phosphotyrosine protein) phosphatases II | 218-455 | 8.7e-64 | 210.9 | In-house | 28-274 (278) | alignment | ||
Range on Protein: 218-455
Range on HMM: 28-274/278.0
TSFLGNPTRNRYRNIPCCDITRVKltdDphfYIHANLVSSGpnPRRFICTQAPLNGTIEEFWKMIIVTGIEYIVMLCELVEKGKPKSAEYFPSqiGQTTK
.||| .|||..|...| .||| | ||.|..... |..||.||.||. |.. ||.|. ||..||||.||||.|. | |.|.|. |..
alylgnldknRykdilpydhsrVk...d...YINAsyidgy..pkkfIatqgPlpstvadfwrmlwelgitvivmltelvelgrekcaqywpe..ggslt
IGRLCTVTKESRVDidKTLVMSTMRISKP---GDNAVVKIVKHIHWRNWPDHGVPDNF--LSPFRLLTVVKN-----------------CTKPIVVHCSA
.|... ... | .. .. |... . |.|.|. .|||||||.. | ..|| ... .|..|||||
ygdftvtllseevl..ddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllsslllldsggpvlVHCsa
GVGRTGTLALILIILESIclPDFIGVPRLLAKLREERFR-AVQTEMQYLYAHRCVLEYLAL
||||||||... ..|| . .. . .. ...||. | |||...|| . ....||.|
GvgRtGtlvaaylmlell..eggvdlleavkelrsqRpglavqnleqyrflyefllelllr
|
|||||||||
| subfamily_Cele-PTP-16_pd | Subfamily Cele-PTP-16 | 218-451 | 2.5e-20 | 67.3 | In-house | 42-277 (303) | alignment | ||
Range on Protein: 218-451
Range on HMM: 42-277/303.0
TSFLGNPTRNRYRNIPCCDITRVKLTDDphFYIHANLVSSGPNpRRFICTQAPLNGTIEEFWKMIIVTGIEYIVMLCELVEKGKPKSAEYFPSQIGQTTK
|. | .||. .. | | ..|||.| ||||. . . .. | || ||. | .||.||| . ...| | | || .
nqfvknmdknrfvdvicldhskvklsds..syihasyleldss.kkailtqlplshtaadfwqmiieqkvkcvlllltdseydklggdsvfprnqdflkf
IGRLCTVTKESRVDIDKTLVMSTMRISKPGDNAVVKIvkhIHWRNWPDHGVPDN----FLS-PFRLLTVVKNCT--KPIVVHCSAGVGRTGTLALILIIL
| | . ||.. . |. . .|. .. ... |...|| .| . |. ..| .|... . .| | .|.||.||.||.
eersirvgefkrvelgdgwvlkvlsvsngdyksflhv...hhykawphnsipsdgspkfvkqiwqlqsvlrkysdstptvymslsgcgragtfalfetah
ESICL-PDFIGVPRLLAKLREERFRAVQTEMQYLYAHRCVLE
|. . . . | ..|. |. ||| |. . . . |
lslhseqasldlvkclenvrngrlhavqnlsqfsvvytllae
|
|||||||||
| 0042113 | (Phosphotyrosine protein) phosphatases II | 219-453 | 6e-64 | 211.1 | In-house | 5-243 (245) | alignment | ||
Range on Protein: 219-453
Range on HMM: 5-243/245.0
SFLGNPTRNRYRNIPCCDITRVKLTDDP----HFYIHANLVSSGPNPRRFICTQAPLNGTIEEFWKMIIVTGIEYIVMLCELVEKGKPKSAEYFPSqiGQ
... |...|||..|...| |||||..|. . ||.|..|. ...||.||.||..|.| ||.|. ||..||||.|..|.|..|.|.|.|. |.
llpenkdknrysdilpydhtrvklspdggdldsdyinasyvdgyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywpl..ge
TTKIGRLCTVTKESRVdiDKTLVMSTMRISKPgDNAVVKIVKHIHWRNWPDHGVPDNFLSPFRLLTVVKN-----CTKPIVVHCSAGVGRTGTLALILII
....|... ... . ...... |..... . .. | |.|. .||||||||. . ...| |.. .|..||||||||||||.......
sltygdftvtllseeh..lddytvrtlevtnl.gddesrevihyhylpwpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylm
LESICLPDFIGVPRLLAKLREERFRAVQTEMQYLYAHRCVLEYL
|| . . .. ...||. | ||||. || . ....||.|
leqlekelgvsleeavkelrsqRpgavqtpsqyrflyeallell
|
|||||||||
| 0037934 | (Phosphotyrosine protein) phosphatases II | 219-453 | 2.4e-60 | 199.4 | In-house | 6-242 (243) | alignment | ||
Range on Protein: 219-453
Range on HMM: 6-242/243.0
SFLGNPTRNRYRNIPCCDITRVKLtDDpHFYIHANLVSSGPnprRFICTQAPLNGTIEE----FWKMIIVTGIEYIVMLCELVEKGKPKSAEYFPsqiGQ
... | ..|||..|...| .|||| .. . ||.|||. | |.|.||.||..|.|. ||.|. ||..||||.||||.|. | |.|.| |.
llpenlsknrysdilpydhsrvkl.eg.sdyinanliyvtp...rliatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqywp...ge
TtKIGRLCTVTKESRVdiDKTLVMSTMRISKPGDNAVVKIVKHIHWRNWPDHGVPDNFLSPFRLLTVVK------------NCTKPIVVHCSAGVGRTGT
. .|... ...... . .. |.... .. . ... | |.|. .||||||||.. . ..| |. . .|..||||||||||||
v.tygdftvtllseeh..lddytvrtlllenldlddltrlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgRtGt
LALILIILESIclpDfIGVPRLLAKLREERFR-AVQTEMQYLYAHRCVLEYL
|......|. . . ... ...||| |. ||||. || . ....||.|
liaaylmllll...g.vdleeavkllreqRpgkavqtpsqyrflyeallell
|
|||||||||
| subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 219-454 | 6.6e-43 | 141.6 | In-house | 16-265 (270) | alignment | ||
Range on Protein: 219-454
Range on HMM: 16-265/270.0
SFLGNPTRNRYRNIPCCDITRVKLT----DDPHFYIHANLVS-SGPNPRRFICTQAPLNGTIEEFWKMIIVTGIEYIVMLCELVEKGKPKSAEYFPSQIG
.. ... |||..| |||.| |. || || | .....|....||. |...||.||. . . |||. .|.|||. | . |.|.. .
eaargkklnRyadiLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpaepk
QTTKIGRLCTVTKESRVDIDKTLVMSTMRISKPGDNavVKIVkHIHWRNWPDHGVPD---NFLSPFRLLTVVKNC---------TKPIVVHCSAGVGRTG
...|. . . .. .. .|. . |.. ..| | .. .||||||| . ||. ||..... ..|..|||||||||||
ekvkledgkikvlalseekeegyiltrlrleekgee..rrlv.HfwyntWpdhgvpreedsslstdqllkmlravrrsekeldkaePllvHcsaGvgRtG
TLALILIILESICLPDFIGVPRLLAKLREERFRAVQTEMQYLYAHRCVLEYLA
|| .. |... . . | .....||..| ||. || .... |.||
tlialDiavrlLeetkkvdvlaiieelRkdRmalvqhpeqyeflykavveyae
|
|||||||||
| subfamily_PTPRA_pd | Subfamily PTPRA | 219-453 | 2.7e-41 | 136.5 | In-house | 54-295 (330) | alignment | ||
Range on Protein: 219-453
Range on HMM: 54-295/330.0
SFLGNPTRNRYRNIPCCDITRVKLTD----DPHFYIHANLVSSGPNPRRFICTQAPLNGTIEEFWKMIIVTGIEYIVMLCELVEKGKPKSAEYFPSQiGQ
| | .||. || | .|| |. . || | . . .|| .| |.. |.|.||.|| |||| || |. . | | |.|.. |
skeenkeknrvvnilPydfsrvilsvkeGveesdyinasfidGykekdkfiaaqGPkeetvedfwrmiweqksativmltelkerkeekcaqywPde.Gl
TTkIGRLCTVTKESRVDIDKTLVMSTMR-ISKPGDNAVVKIVKHIHWRNWPDHGVPDNFLSPFRLLTVVKNCT----KPIVVHCSAGVGRTGTLALILII
| | . ... | .| |. .. ... .. ...|. .|.. ||| ||| . ..|| ||.. |||||||||||||||. . .
vt.yGnirvevedetvlvdytvrkflvqqlpdatrekksrlvrqfhftswPdvGvPfepiGmlkllkkvkklnqqsagpivvhcsaGvGrtGtfivldav
LESICLPDFIGVPRLLAKLREERFRAVQTEMQYLYAHRCVLEYL
|| . . | . . .|| | . |||..|| . .. .|||
lervkaerkvdvfefvkrlrlqrpqmvqtdeqyefiykvlleyy
|
|||||||||
| subfamily_PTPN1_pd | Subfamily PTPN1 | 219-452 | 3.2e-39 | 129.4 | In-house | 28-270 (290) | alignment | ||
Range on Protein: 219-452
Range on HMM: 28-270/290.0
SFLGNPTRNRYRNIPCCDITRVKLTDDPHFYIHANLVSSGPNPRRFICTQAPLNGTIEEFWKMIIVTGIEYIVMLCELVEKGKPKSAEYFPSQIG-QTTK
. | ..||||.. | .|.|| .. || |.|| |..| || || |.. ||.|. .||| ..|||.. | |.|.|.. .. .
klpenrnlnryrdvspydhsrikleradndyinaslveleeakrsyiltqGPlpntvdhfWqmvWeqkskavvmlnkvvekeqikcaqywPqgeeekell
IGRLCTVTKESRVDIDKTLVMSTMRISKPGDnAVVKIVKHIHWRNWPDHGVPD------NFLSPFRLLTVVKNCTKPIVVHCSAGVGRTGTLALILIILE
. | . .. .. ....... . . . | |. ||| |||. .|| | .... | |.|||||.||.||..|. .|
ledtklkvkliseerksyytvrllelenlkt.qetreilhfhyttwpdfgvpespaaflkflfkvresGslssdvGpavihcsaGiGrsGtfclvdtclv
SICL---PDFIGVPRLLAKLREERFRAVQTEMQYLYAHRCVLEY
| . . . . | .||. |. .|| | ... .||
liekkddlssvdikkvllelrkyrlGliqtadqlrfsylaileG
|
|||||||||
| subfamily_PTPN14_pd | Subfamily PTPN14 | 219-454 | 1.7e-36 | 120.8 | In-house | 45-297 (300) | alignment | ||
Range on Protein: 219-454
Range on HMM: 45-297/300.0
SFLGNPTRNRYRNIPCCDITRVKLT---DDPHFYIHANLVS--SGPNPRRFICTQAPLNGTIEEFWKMIIVTGIEYIVMLCELVEKGKPKSAEYFPSQ--
. | .||.... . .||.|. .. . || | .. | . | .| .|.||. |...||.|. .|.. |||| | |.|| || .|||..
klpenaeknrfkdvlPyednrvelsptkenstgyinassikvsvggkersyivaqgPleltvqdfWqmvWeqgvqlivmlteeeedgkeksfkyfPkles
IGQTTKIGRLCTVTKeSRVDIDkTLVMSTMRISKPGDnAVVKIVKHIHWRNWPDHGVPDN---FLSPFRLLTVVK----------NCTKPIVVHCSAGVG
.| . |. .|| . | | ... ..... . | |. . .|||||||.. ||| . . |. . |..||||||||
kkktvefgkfkvttk.fsedsd.svittglklkhlps.keertvwhlqytDWpdhgvPeDvkgflsyLeevqsvrrktnseveskeskPPvlvhCsaGvG
RTGTLALILIILESICLPDFIGVPRLLAKLREERFRAVQTEMQYLYAHRCVLEYLA
||| | | ...... . | ... ||.||| | ||| || . .. ...||
rtGvlilsdlliatlehneeidikkvlarLreqrmllvqtlaqYkfvYkvlikylk
|
|||||||||
| 0049772 | (Phosphotyrosine protein) phosphatases II | 219-455 | 2.2e-33 | 111.7 | In-house | 42-282 (314) | alignment | ||
Range on Protein: 219-455
Range on HMM: 42-282/314.0
SFLGNPTRNRYRNIPCCDiTRVKLtD----DPHFYIHANLVSSGpnpRRFICTQAPLNGTIEEF----------WKMII--VTGIEYIVM----------
... |...||| .|.. | .||.| . . . ||.|. |.. ..||.||.||. |.. | |.|.. . .|||
dlflnrdknryldilpad.nrvil.pglpvsgsdyinasyvdgf...lkfIatqgpleitvvdfreepvlyyngwrmvlrgdlnvrdivmsrdevladel
-----------LCELVEKGkpksAEYFPSQIGQTTkigrlctvtkesrvdidktlvmstmrisKPG--DNAVVKIVKHIHWRNWPDHGVPdNFLSPFRLL
|..| ..| .|. .. . . . .. . . . . .. ..||...| . ..|
srLdaAlgKtpllildgng....neptaadlellk............................eelydpelferlgikylripvpDgsap.lledfdefl
TVVKN--CTKPIVVHCSAGVGRTGT--LALILIILESICLPDFIGVPRLLAKlREERFRAVQTEMQYLYAHRCVLEYLAL
.... .|..|||.||.||||| .| .|..| ..| . . || ....... .||.. ....||||
efieeadkggpvlvHCkaGkgRtgtfvvaaylmkllgvsleealedvrlkRp.inpnpgfieqleqyefilealleylkf
|
|||||||||
| subfamily_egg_pd | Subfamily egg | 219-453 | 7.5e-32 | 105.2 | In-house | 35-270 (307) | alignment | ||
Range on Protein: 219-453
Range on HMM: 35-270/307.0
SFLG-NPTRNRYRNIPCCDITRVKLTDDPH-F---YIHANLVSSGPNPRRFICTQAPLNGTIEEFWKMIIVTGIEYIVMLCELVEKgkPKSAEYFPSQIG
.. | .. | . ..| | .|||| . .|||| |. .| ||..|||| | ..||.|. ..||||| .| . |.|
aasdnnlekarskrvhckdssrvklelrrGqylddfihanrvkGkpllnefilaqaplkntvddfwrmvfqeevqyivmltsrkes..erceyywpkaes
QTTKI--GRLCTVTKESRVDIDKTLVMSTMRIskPGDNAVVKIVKHIHWrnwpDHGVPDNFLSPFRLLTVVKNCTKPIVVHCSAGVGRTGTLALILIILE
.. .. | | . . | . .. ... | . . ..| . | . ||.|.| ..| .||.||.. || ...|| | | |
dslvtvpGslrienlkvdskadplfrvtklkl..vGgddeerflehwqg....dvnnssdvysplrvlrklrnlskpvvvqdilGvskaatlvaieiall
SICLPDF--IGVPRLLAKLREERFRAVQTEMQYLYAHRCVLEYL
|. | | || .| .|.. ..||. .| || ..
sllrGpitkslvlravvflrlrrrlsvesvllylfvyrlvlfff
|
|||||||||
| subfamily_PTPN23_pd | Subfamily PTPN23 | 220-452 | 7.6e-46 | 151.2 | In-house | 40-279 (288) | alignment | ||
Range on Protein: 220-452
Range on HMM: 40-279/288.0
FLGNPTRNRYRNIPCCDITRVKLTDDPHFYIHANLVSS-GPNPRRFICTQAPLNGTIEEFWKMIIVTGIEYIVMLCELVEKGKPKSAEYFPSQIGQTTKI
....||.|.| | .|||| . || | | . | ||.|||||..|. .||.|. . |||| . |.|||| ..|.|.. |.|.|
aklyseknrsrdilPyDhnRvklrgskDDYinAsfvkdlspgcPdfiatqaPlqstlnDFWlmvyeqkssviVmllskeelgkpkvdrYwPedkgetvkf
GRLcTVTKESRVDIDkTLVMSTMRISKPGDNaVVKIVKHIHWRNWPDHGVPDNFLSPFRLLTVVKN--------CTKPIVVHCSAGVGRTGTLALILIIL
| | .|| .| . . | | ..... . . || |.|... .||..|||. . ...| .|.. . .|.||||||||||||..||. ..
gdl.svtlksvrete.thvervlkletldad.avksvshlqltsWpelGvPasPetllqfldevesayeavqrksktPlvvhCsaGvgRtgvfalvyaav
ESIC-LPDFIGVPRLLAKLREERFRAVQTEMQYLYAHRCVLEY
. . . . ..... .|||.| ||.. |. . |||.
relekgnglldiiqvvsrlreqRrfmvqekeqlkfsyeavlea
|
|||||||||
| subfamily_PTPN3_pd | Subfamily PTPN3 | 220-451 | 1e-45 | 150.9 | In-house | 38-273 (280) | alignment | ||
Range on Protein: 220-451
Range on HMM: 38-273/280.0
FLGNPTRNRYRNIPCCDITRVKLTDDPHFYIHANLVSSGPNP----RRFICTQAPLNGTIEEFWKMIIVTGIEYIVMLCELVEKGKPKSAEYFPSqIGQT
| ..||||.| |.|||||.. . || || |. . |.| || ||. | ..||.|. .. |||| .|||.|. | .|.|. ...
kpenlsknryrdilpydatrvklkesetdyinanyvnmeipstglvnryiatqGPlaktatdfWqmvweqksslivmlttlverGrvkChqyWPe.tede
TKIGRLCtVTKESRvDIDKTLVMSTMRISKPGDNaVVKIVKHIHWRNWPDHGVPDNFLSPFRLLTVVKNCT----KPIVVHCSAGVGRTGTLALILIILE
.. |.. |. |.. | .|. |. . ... . . . .. . .||||||||. . ..... |... .|.|||||||.|||| | |. . |
leygefs.vkceke.detksyvlrelvlkdketk.eerkilqlqylaWpdhgvPddsadflefvervrklrsgkeePvvvhCsaGigrtGvlilletala
SICLPDFIGVPRLLAKLREERFRAVQTEMQYLYAHRCVLE
| . . .. .. ..|. | |||. || . ..|.
lieaaepvypldivrtmrdqramlvqtasqykfvCeailk
|
|||||||||
| subfamily_PTPRB_pd | Subfamily PTPRB | 221-456 | 7.8e-57 | 187.5 | In-house | 49-288 (293) | alignment | ||
Range on Protein: 221-456
Range on HMM: 49-288/293.0
LGNPTRNRYRNIPCCDITRVKL----TDDPHFYIHANLVSSGPNPRRFICTQAPLNGTIEEFWKMIIVTGIEYIVMLCELVEKGKPKSAEYFPSQIgQTT
| ..|||.|| | .|||| ... || || .. || || || || .|...||.|. . . |||| .|||||| | ||.|.. ...
avnraknrytnilpydhsrvkLaalkdesgsDYinanyipgynsprefiatqGPlpetvddfWrmvwekkssiivmltqlvekgkvkCeeYWPade.epv
KIGRLcTVTKESRVDIDkTLVMSTMRISKpgdNAVVKIVKHIHWRNWPDHGVPDNFLSPFRLLTVVKNCT------KPIVVHCSAGVGRTGTLALILIIL
| . .|| . . . |. ...|.| . . |.. |. |||||||.. . ... |.. . .|||||||||||||||. . .|
lyGdi.kvtlvaeeele.dwvirelkiek...ekeerkvrqyhftsWpdhgvPektktlldfvrtvreaiektaskrPivvhCsaGvGRtGtfialdrll
ESICLPDFIGVPRLLAKLREERFRAVQTEMQYLYAHRCVLEYLALK
..| |.. . ..|.|||||. |||| ||.. |.|||..| |
qaieeedyvdifgivaelReeRnllvqtekqYifihqcvldllrkk
|
|||||||||
| subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 222-455 | 6.1e-45 | 148.4 | In-house | 8-244 (250) | alignment | ||
Range on Protein: 222-455
Range on HMM: 8-244/250.0
GNPTRNRYRNIPCCDITRVKLTDD----PHFYIHANLVSSGPNPRRFICTQAPLNGTIEEFWKMIIVTGIEYIVMLCELVEKGKPkSAEYFPSQigQTTK
| .||| .| | .|| | . || | . . . . || ||.||. |||.||.|.. .. |||| .|.|..| .|.| . ...|
qnkeknryadiialdssrvvLekekgdkesdyinasflhgyderkafiatqgPlqatiedfWrmvleeksgtivmLtnLkesekt.yhqywPve..kaek
IGRLcTVTKESRvDIDKTLVMSTMRISKPGDnAVVKIVKHIHWRNWPDHGVPDNFLSPFRLLTVVKNC-----TKPIVVHCSAGVGRTGTLALILIILES
| . ||. |. .. ... .. .|| | .||...|. .||| |||.. . . ||. |. ..|..|.|||||||.|. | .||
yGdv.tvsllsk.eefadytkrklklskakk.aderivrqlhfvvWPdkgvPevatavLellkkvqasqqqagnaPvivqCsaGvgrsGafiaidavler
ICLPDFIGVPRLLAKLREERFRAVQTEMQYLYAHRCVLEYLAL
. . | ... .||..| .||... || . .. .|..|
lkkekvvdvfkvikvlrkdrphavesleqyvfvyeiilkalds
|
|||||||||
| subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 222-468 | 3.8e-37 | 123.3 | In-house | 24-270 (284) | alignment | ||
Range on Protein: 222-468
Range on HMM: 24-270/284.0
GNPTRNRYRNIPCCDITRVKLTD----DPHFYIHANLVSSGPNPRRFICTQAPLNGTIEEFWKMIIVTGIEYIVMLCelvekgKPKSAEYFPSQIGQTTK
| .||. .| | ..||| . || | .. .. ..| || ||. |...||.|| . ||.| | | ..|.| .| .. .
qnkdknrighilafdknvvklerliGeefsdyinasfitGyqrkdkyiatqGPldntladfWrmiweyncstivllt......kdkcsqywplkivikee
IGRLCTvtkeSRVDIDKTLVMSTMRISKPGDNAVVKIVKHIHWRNWPDHGVPDNFLSPFRLLTV------VKNCTKPIVVHCSAGVGRTGTLALILIILE
... . |. . |. ...|. | . .. .. |.. |||.|||| .||. .| ..|||||||||||||. . ..|.
rfkvkv....dsveeseeyvvrdielsedgkekdirkirqfhflgwpdvgvpdypsdlmrlvkkvrhltskenhranivvhcsagvgrtgvyivldvlld
SICLPDFIGVPRLLAKLREERFRAVQTEMQYLYAHRCVLEYLALKKYVQSREDFAKF
. . . | ... .||..| . || .|| . . .|| . . . ||. .
rmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysalleehlfghsdvalpdfpay
|
|||||||||
| subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 222-454 | 7.6e-35 | 115.2 | In-house | 45-284 (290) | alignment | ||
Range on Protein: 222-454
Range on HMM: 45-284/290.0
GNPTRNRYRNIPCCDITRVKLT------DDPHFYIHANLVSSGPNPRRFICTQAPLNGTIEEFWKMIIVTGIEYIVMLCELVEKGKPKSAEYFPSQigQT
| ..||..|| | |. | | .. ||.| . . ...| ||.|.. |. .|||.| . ||||.. .|.|| | |.|.. .|
snkllnRfanivvyddnritLrpisghkDCtneyinAcyikgykekkqyiatqgpvsntlvdFWkliwqekvtiivmltniieegkvkCqqYWpds..dt
TKIGRLC-TVTKESRVDidkTLVMSTMRISKPGDNAVVKIVKHIHWRNWPDHG-VPDNF--LSPFRLL--TVVKNCTKPIVVHCSAGVGRTGTLALILII
...| ....|. .. . . .... . .. ..|.. . ||...| |... |. .. | |. ..||||||..|||.... . .
kaygefsikllneetln...eyierklevknknsagakqsvtqyqitnwdstgkvtnpqtillvieemyktqrkrgntsivvHCSdtvgrsavfcaaatt
LESICLPDFIGVPRLLAKLREERFRAVQTEMQYLYAHRCVLEYLA
.. | | .| ..| . |||. || . .. ||.||
inkcktegvidvfqvlksqRiqkpgsvqtvqqyqgifqivltyld
|
|||||||||
| subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 222-453 | 5.7e-32 | 105.6 | In-house | 37-277 (287) | alignment | ||
Range on Protein: 222-453
Range on HMM: 37-277/287.0
GNPTRNRYRNIPCCDITRVKLTDDPHF---YIHANLVSSGPNPRRFICTQAPLNGTIEEFWKMIIVTGIEYIVMLCELVEKGKPKSAEYFPSQiGQTTKI
. .||| .. | ||| |. .... || || |.| . .||..|.|. |. .||.... | .... ||... | .|.| . . ..
aavkknryadvlPiddtrvllsaegelGsdyinanyvasytddeafiaaqgPiaatvrdfwravletrsasvitmtreveearlkcykywPer.evPmrv
GrLCTVTKESRVDIDKTLVMSTMRISKPgDNAVVKIVKHIHWRNWPDHGVPDNFLSPFRLLTVV---------KNCTKPIVVHCSAGVGRTGTLALILII
| .|. .. . . ..|. . . ..|| ... .|||.... .. |. | . . |.|||...|.||.|.| .|..
G.GysvvlldydikePeygvralrlidl.etrearvvkqldllswPdkvlaPtavglirfvldvkqhielardasevGPlvvhddvGiGrsGillatlvl
LESICLPDFIGVPRLLAKLREERFRAVQTEMQYLYAHRCVLEYL
.. . | . ...||| | ||. .|. . . |
vsrledlGrvdvaavvirlreyraalvqavvqlrllyealvtyy
|
|||||||||
| Y_phosphatase | Protein-tyrosine phosphatase | 223-451 | 2e-68 | 225.7 | Pfam-A | 1-235 (235) | alignment | ||
Range on Protein: 223-451
Range on HMM: 1-235/235.0
NPTRNRYRNIPCCDITRVKL--TDDPHFYIHANLVSSGPNPRRFICTQAPLNGTIEEFWKMIIVTGIEYIVMLCELVEKGKPKSAEYFPSQIGQTTKIGR
| ..|||..|...| ||||| ...|. ||.|| |.. .....||.||.||. |||.||.|.. ...||||..|.|||. | |.|.|.. ..... |.
nkkknRykdilpydktrvklkgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeesltygd
LCTVTKESRVDIDKTLVMSTMRISKPGDNAVVKIVKHIHWRNWPDHGVPDNFLSPFRLLTVVKNCT----KPIVVHCSAGVGRTGTLALILIILESICLP
.. .||. ...| ........| ... ..||..|. ||||||||.. | ..|.. |.. . .|.|||||||||||||.... |.||..
ikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldilleqleae
DFIGVPRLLAKLREERFRAVQTEMQYLYAHRCVLE
. . | .. .||..|. .||.. || . ....||
eevdvlqivkelRkqRpgmvqsleqYiflykaile
|
|||||||||
| Y_phosphatase | Protein-tyrosine phosphatase | 223-451 | 2e-68 | 225.7 | In-house | 1-235 (235) | alignment | ||
Range on Protein: 223-451
Range on HMM: 1-235/235.0
NPTRNRYRNIPCCDITRVKL--TDDPHFYIHANLVSSGPNPRRFICTQAPLNGTIEEFWKMIIVTGIEYIVMLCELVEKGKPKSAEYFPSQIGQTTKIGR
| ..|||..|...| ||||| ...|. ||.|| |.. .....||.||.||. |||.||.|.. ...||||..|.|||. | |.|.|.. ..... |.
nkkknRykdilpydktrvklkgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeesltygd
LCTVTKESRVDIDKTLVMSTMRISKPGDNAVVKIVKHIHWRNWPDHGVPDNFLSPFRLLTVVKNCT----KPIVVHCSAGVGRTGTLALILIILESICLP
.. .||. ...| ........| ... ..||..|. ||||||||.. | ..|.. |.. . .|.|||||||||||||.... |.||..
ikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldilleqleae
DFIGVPRLLAKLREERFRAVQTEMQYLYAHRCVLE
. . | .. .||..|. .||.. || . ....||
eevdvlqivkelRkqRpgmvqsleqYiflykaile
|
|||||||||
| subfamily_PTPN12_pd | Subfamily PTPN12 | 223-454 | 1.5e-52 | 173.3 | In-house | 40-278 (290) | alignment | ||
Range on Protein: 223-454
Range on HMM: 40-278/290.0
NPTRNRYRNIPCCDITRVKLTDD----PHFYIHANLVSSGPNPRRFICTQAPLNGTIEEFWKMIIVTGIEYIVMLCELVEKGKPKSAEYFPSQIGQTTKI
| ..|||..| | .||.|. . || ||.. . .. ..| .|.|| |...||.||. . .| .||.|..|| || | . |.|.. ......
nvkknrykDilPydksrvelskieeeegsdYinanfikgvegkleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkkCerYWpeegeeelef
GRLCtVTKESRVDIDKTLVMSTMRISKPgdnAVVKIVKHIHWRNWPDHGVPDNFLSPFRLLTVVKNCT----KPIVVHCSAGVGRTGTLALILII---LE
| .. ||.|. .|. ... |... . ..|. .|...||||||| .. | ..|.. |.. .|.|||||||||||||. | .. |.
gefe.vtleeekavdddflirtLkveaq...kesrkvyqfhYtaWPDhgvPssaksllelielvrelqesedaPlvvhCsaGvGrtGtiiaidyvrellk
SICLPDFIGVPRLLAKLREERFRAVQTEMQYLYAHRCVLEYLA
. .|. . | |...||..| .|||. || . ...|.|..
aekipeeldvfdlvlelrkqraalvqtkeqyelvykavaelvq
|
|||||||||
| subfamily_PTPN13_pd | Subfamily PTPN13 | 223-454 | 1.3e-47 | 157.3 | In-house | 37-270 (273) | alignment | ||
Range on Protein: 223-454
Range on HMM: 37-270/273.0
NPTRNRYRNIPCCDITRVKLTDDPHfYIHANLVS--SGPNPRRFICTQAPLNGTIEEFWKMIIVTGIEYIVMLCELVEKGKPKSAEYFPSQIGQTTKIGR
| ..|||||. .| ||||| |. || |.|. | . ..| .| || |...||.|. | |.|. .|||| | |.|.. ....|.
nkdknryrnvlPydetrvklgdegg.yinaslikvpvgkdeyeyiacqGPlPetvkdfwqmvweqkaeviamvtlekekgkvkchrywPesknkklkvsn
LCTVTKESRVDIDkTLVMSTMRISKPGDNAVvKIVKHIHWRNWPDHGVPDNFLSPFRLLTVVKNCTK---PIVVHCSAGVGRTGTLALILIILESICLPD
.|... .. | ..|.... ... ... . | |... .||||||| . .. .... |.. . |||||||||.||.||| | ..|. |
rlevellkvqkld.gfvvralavkdsesges.revahlnfvkwPdhgvPssaaellqfvaevrrlqtdagPivvhcsaGiGrsGtlitidvvlglierdk
FIGVPRLLAKLREERFRAVQTEMQYLYAHRCVLEYLA
. | .. |||| | |||. ||.. .. .|| |
efdvkeivrklreqrqgvvqtkdqyifvykailevlk
|
|||||||||
| 0041856 | (Phosphotyrosine protein) phosphatases II | 223-459 | 1.2e-44 | 147.4 | In-house | 1-177 (182) | alignment | ||
Range on Protein: 223-459
Range on HMM: 1-177/182.0
NPTRNRYRNIPCCDITRvkltddPHFYIHANLVSSGPNPRRFICTQAPLNGTIEEFWKMIIVTGIEYIVMLCelvekgkpkSAEYFPsqigqttkigrlc
| ..|||..|...| .| . ||.|||. .. ..|||.||.||..|...|..|. || .||.|. . |.|
nldknrysdilpydhsr......dldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlt.........eelywp.............
tvtkesrvdidktlvmstmriskpgdNAVVKIVKHIHWRNWPDHGVPDnFLSPFRLLTVVKNCTKPIVVHCSAGVGRTGTLALILIILESiclpdFIGVP
. . . . .... .|||||||| . . .... |.. .|..|||||||||||||... .... ....
..........................ellerlgiqylylpwpDhgvpd.ldelldfieevleeggpvlVHCsaGvgRtgtlvaaylmkkl.....gvsle
RLLAKLREERFRAVQTEMQYLYAHRCVLEYLALKKYV
.. .|. |. .|.|. || . ....||.| |||..
eavklvrsrRpgmvitpnqyfflqlallellllkktr
|
|||||||||
| subfamily_PTPN6_pd | Subfamily PTPN6 | 223-459 | 9.4e-44 | 144.6 | In-house | 54-303 (306) | alignment | ||
Range on Protein: 223-459
Range on HMM: 54-303/306.0
NPTRNRYRNIPCCDITRVKLTDDPH---FYIHANLVS---SGPNpRRFICTQAPLNGTIEEFWKMIIVTGIEYIVMLCELVEKGKPKSAEYFPSQIGQTT
| ..|||.|| | |||.|... || || .. | . ...| || |. |...||.|. . |||. . ||.|| | | |.|.. ...
nkeknryknilPfDhtrvilkepsvpgsdyinanyikkevkgsd.ksyiatqgclettvsdFWrmvwqensrvivmttkevErgkekCarYWPdeeekee
kIGRLcTVTKESRvDIDKTLVMSTMRISKPGDNAVVKIVKHIHWRNWPDHGVPDNFLSPFRLLTVVKN---C-----TKPIVVHCSAGVGRTGTLALILI
|.. .||. | . .. .. ....|| .. . | . |...||||||| . .|. |.. . |||||||||.|||||. .| |
.yGki.svtnvse.ksladYilRelsvskkkkkkeerevfqyhfksWPdhgvpkdpgavLdfledvnrkqeeleeaeagpivvhCsaGiGRtGtfiviDi
ILESICLPD---FIGVPRLLAKLREERFRAVQTEMQYLYAHRCVLEYLALKKYV
.|. | | . .| ..|| | |||| || . .. . .|. || .
llkliekkgldadidiqklvksvreqrsglvqteqqykfvykaikkyietkkkl
|
|||||||||
| subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 223-457 | 1.8e-35 | 117.5 | In-house | 51-288 (297) | alignment | ||
Range on Protein: 223-457
Range on HMM: 51-288/297.0
NPTRNRYRNIPCCDITRVKLT---DDP-HFYIHANLVSSGPNprRFICTQAPLNGTIEEFWKMIIVTGIEYIVMLCELVEKGKpKSAEYFPSQiGQTTkI
| ..||.|| | |||| ||| |. | | . . |.|.|| | . |...||.|.. . |||| .. |. | | | |.. . | ||
nfeksRYkniLPydssRvkLaivnddpdsDyvnasfvkgnkh..rlittqmPmkatvadfWamvldeqvstivmlnddnerdk.kcaryWsdk.gvtt.f
GRLCtVTKESrVDIDKTLVMSTMRISKpGDNAVVKIVKHIHWRNWPDHGVPD--NFLSPFRLLTVVKN-----CTKPIVVHCSAGVGRTGTLALILIILE
| . |. .| |. . . .. ..| |.. . ..|| .. .|||. |. . | |.. |.. |..|||.||||||| | |. ..
Gdvs.vvlls.vsereGfikrelevtk.gkakarrvvkqyqfveWPdkaverkdsassllklisevrkdfsqnaegPllvhclaGvGrtgvlltidsvva
SICLPDFIGVPRLLAKLREERFRAVQTEMQYLYAHRCVLEYLALKK
. . . . |. |||.|| |||. || . . |||.| ..
eakrekevdifglvkklrqerpylvqtkeqykfvyvavleallsed
|
|||||||||
| subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 223-451 | 5.8e-28 | 92.7 | In-house | 7-238 (239) | alignment | ||
Range on Protein: 223-451
Range on HMM: 7-238/239.0
NPTRNRYRNIPCCDITRV---KLTDDPHF-YIHANLV-SSGPNPRRFICTQAPLNGTIEEFWKMIIVTGIEYIVMLCELVEKGKPKSAEYFPSQigqTTK
| ..||| || | .|| ||..||| || |. . .|. .|.|| .. . .||.|. |||| |.| | | .|.| |.|
nkaknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpds...tsk
IGRLCTVTKESRVDIDktLVMSTMRISKPGDNAvVKIVKHIHWRNWPDHGVPDNFLSPFRLLTV-VK---NCTKPIVVHCSAGVGRTGTLALILIILESI
| ... | | .. |. .|. |. . | . |. |||.|||. . . | | ..| |.||||||||||.. .| .|
ycnlrvtlrktevfad..yiirtfvmsqvgqte.eryvyqyhftvwpdkgvpqyatavlglrrkitkdslpgarpwvihcsagvgrtgaflvidamlrqa
CLPDFIGVPRLLAKLREERFRAVQTEMQYLYAHRCVLE
. . . .||.| . ||| ||.. | .|||
kkqktvdifnyvkairedrphmvqtseqyvfihlavle
|
|||||||||
| subfamily_Sponge-PTP9_pd | Subfamily Sponge-PTP9 | 223-457 | 6.6e-28 | 92.3 | In-house | 40-297 (301) | alignment | ||
Range on Protein: 223-457
Range on HMM: 40-297/301.0
NPTRNRYRNIPCCDITRVKLTDDPH------FYIHANLVSSGPNPRRFICTQAPLNGTIEEFWKMIIVTGIEYIVMLCELVEKGKPKSAEYFPSQIGQTT
| . ||..|| | |. |. |. || |. ... . ..|| .|.|.. |. .||..|. |||...| |. | |. .|.|. ...
nkalnrfknitvyddnriilkpkpnldlcqreyinasyidgysekkkfiaaqgpmkktlvdfWrliwqekpvsivmvtnlkegtkskceqywpnseaese
KIGRLCTVTKESRVDIDKTLVMSTMRISKPGDNAVVKIVK------------HIHWRNWPDHGVPDNFLSPFRLL-----TVVKNCTKPIVVHCSAGVGR
. | . . ... | | .. ...| . .|. .. .. .||..|| . . . . | |.|||||..|.|
efgpftvtlvneqvyPdfvirqlnvkiqdgsnngyierkfkvksdksswdvlqlqvtdWpqdGvvreprtvLqviddvihrqqkigggpvvVHCSdtVsr
TGTLALILIILESICLPDFIGVPRLLAKLREERFRAVQTEMQYLYAHRCVLEYLALKK
.|. . | || . | . .| . ||.| || . . .||.|..
sGvYcsvsiglEQckaegVVdvfqvtkavrrskpgaVtTLeqytsiydvidmylqlns
|
|||||||||
| subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 223-451 | 7.4e-28 | 92.3 | In-house | 8-239 (239) | alignment | ||
Range on Protein: 223-451
Range on HMM: 8-239/239.0
NPTRNRYRNIPCCDITRV---KLTDDPHF-YIHANLV-SSGPNPRRFICTQAPLNGTIEEFWKMIIVTGIEYIVMLCELVEKGKPKSAEYFPSQigqTTK
| ..||| || | .|| ||..||| || |. . .|. .|.|| .. . .||.|. |||| |.| | | .|.| |.|
nkaknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpds...tsk
IGRLCTVTKESRVDIDktLVMSTMRISKPGDNAvVKIVKHIHWRNWPDHGVPDNFLSPFRLLTV-VK---NCTKPIVVHCSAGVGRTGTLALILIILESI
| ... | | .. |. .|. |. . | . |. |||.|||. . . | | ..| |.||||||||||.. .| .|
ycnlrvtlrktevfad..yiirtfvmsqvgqte.eryvyqyhftvwpdkgvpqyatavlglrrkitkdslpgarpwvihcsagvgrtgaflvidamlrqa
CLPDFIGVPRLLAKLREERFRAVQTEMQYLYAHRCVLE
. . . .||.| . ||| ||.. | .|||
kkqktvdifnyvkairedrphmvqtseqyvfihlavle
|
|||||||||
| subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 223-452 | 6.2e-27 | 89.3 | In-house | 33-258 (267) | alignment | ||
Range on Protein: 223-452
Range on HMM: 33-258/267.0
NPTRNRYRNIPCCDITRVKLTDDPHFYIHANLVSSGPNPRRFICTQAPLNGTIEEFWKMIIVTGIEYIVMLCELVEKgkpKSAEYFPSQIGQTTKIGRLC
| |||. . | ||| | . . || | | . . || || ||. || .|...|. .. ||.| . . ..| ..||. | |
nqernrlddnlpyddtrvilrtkeeeyinasyvegyktknafivtqdplkntitdfltvihdqkvpvivlltkvftd...nirlfwPPkmgqakkyqdlt
TVTKESRVDIDKTLVMSTMRISkpgdNAVVKIVKHIHWRNWPDHGVPDNFLSPF-RLLT--VVKNCTKPIVVHCSAGVGRTGTLALILIILESICLPDFI
. . | .. ... | . | ....| .| |. .|. ..| .|.||.||.||||.||. | || . .
vehslekeendyqiitlelkfk....nesahnvtlyyykkwnintnnkpylkplfgilaknqlengnrPlvvacsdGvGrsGtflvidsqleraktegvs
GVPRLLAKLREERFRAVQTEMQYLYAHRCVLEY
. .| |.|. | |.| .|.| |. . ||
difdflrkirsqriglvdtkeryiyihellaey
|
|||||||||
| subfamily_ptpA1_pd | Subfamily ptpA1 | 223-411 | 5.5e-25 | 83.0 | In-house | 47-254 (418) | alignment | ||
Range on Protein: 223-411
Range on HMM: 47-254/418.0
NPTRNRYRNIPCCDITRVKLTD----DPHFYIHANLVSsGPNPRRFICTQAPLNGTIEEFWKMIIVTGIEYIVMLCELVEKGKPKSAEYFPSQIGQT--T
| ..||| || . |||.| . || || . | |..||||| || || .||.|. |||| |. . | |.| ||| .
ntsknrytnilpvnhtrvqlkkiqdkegsdyinanyid.gaypkqfictqgplpntiadfwrmvwenrcriivmlsresencrikcdrywpeqiggeqfs
KIGRLC-------TVTKESRVDIDKTLVMSTMRISKPGDNavvKIVKHIHWRNWPDHGVPDNfLSPFR-LLTVVKNC----------TKPIVVHCSAGVG
| | | .. .. .|.. |. . . . .. |||| .|| ||| || . | ||.||||||||
iygngnevfgtysvelveviqdpereiitrnirltfeget...rditqyqyegwpdhnipdh.tqpfrqllhsitnrqnqiipssdrnvpiivhcsagvg
RTGTLALILIILE
||||.. .|...
rtgtfctavimmk
|
|||||||||
| subfamily_eak_pd | Subfamily eak | 223-369 | 4.2e-10 | 33.5 | In-house | 52-195 (332) | alignment | ||
Range on Protein: 223-369
Range on HMM: 52-195/332.0
NPTRNRYRNIPcCDITRVKLTD---DPHFYIHANLVSSGPNPRRFICTQAPLNGTIEEFWKMIIVTGIEYIVMLCELVEKGKPKSAEYFPSQIGQTTKIG
. || .. .| | |.|| .. || | |. |..| | .. . . ||.|.. ||.| | ||.. || ||| . . | |
avnrnvvkivp.ydrylvrltssqlnrlGyinaslaefsevGrkyiltGiasedkvfafwqmvleqkspaivqlledvelkleksdkyfpdktreelkfG
RLCTVTKESrVDIdKTLVMSTMRISKpGDNAvvKIVKHIHWRNWPDHGVP
| .|| | . | . . .|| |... . |.| . | . .|
ildverkef.vkr.niletrllelsk.Gnet..hrvlhykvfGwtettlp
|
|||||||||
| subfamily_Sponge-PTP6_pd | Subfamily Sponge-PTP6 | 224-465 | 1.2e-31 | 104.6 | In-house | 49-291 (439) | alignment | ||
Range on Protein: 224-465
Range on HMM: 49-291/439.0
PTRNRYRNIPCCDITRVKLTDD---PH-FYIHANLVSSGPNPRRFICTQAPLNGTIEEFWKMIIVTGIEYIVMLCELVEKGKpksaeYFPSQigQTTKIG
|.|||... | ||| | . || || || . ... .| ||.| . | ..||...| ||||..||| | |.||. . . |
qtknrykdvgafdhtrvtlqeipgvphshyinanyikGyyddklyiatqgpkkettddfwrlviekktvtivmltnlvesyk.....ywpsd..aevcyg
RLcTVTKESRVDIDKTLVMSTMRISKPGDNAVVKIVKHIHWRNWPDHGVPD--NFLSPF-RLLTVV--KNCTKPIVVHCSAGVGRTGTLALILIILESIC
. .| . ... . . . . . . | ..|. |||. || ... | | . |. . |.|||||||||||||. . | || .
di.avrvdrnielpnyvirgfkvfnerdttekertvlqfhyiawpdknvpaqashvldflrainsandkeeygpvvvhcsagvGrtGtiialdialeqlk
LPDFIGVPRLLAKLREERFRAVQTEMQYLYAHRCVLEYLALKKYVQSREDF
| . . . .. ||..| . ||. ||.. . .||| . . . ..|
lenkvdikgivkvlrkqrkqmvqalcqyvfiynavledivyGdiavtidef
|
|||||||||
| subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 224-451 | 1.1e-28 | 95.0 | In-house | 4-237 (237) | alignment | ||
Range on Protein: 224-451
Range on HMM: 4-237/237.0
PTRNRYRNIPCCDITRVKLTD--DPHFYIHANLVSS-GPNPRRFICTQAPLNGTIEEFWKMIIVTGIEYIVMLCELVEKGKPKSAEYFPSQiGQTTKIGR
.||| || . | .|| | || |. . . |...|..| ||. . ..||.|. |||| |.|. . | .|.|| | . |
kiknrygnivaydhsrvvlkgagsgsdyinatylkgfdgtpkkyiaaqgplesscddfwqmvwqekcsvivmltgliegnelkchkywpst.dqpaaygv
LCTVTKESRVDIDKTlVmSTMRISKPGDNAVVKIVKHIHWRNWPDHGVPDNFLSPFRLLTV-VKN-----CTKPIVVHCSAGVGRTGTLALILIILESIC
| | | | | .. .|| . |.... .. |||.|||.. . .|. ... . | ..|||||||||| . .| .|
ltvslkkkeefsdyt.v.rslllskrltlkevrlihqyqftswpdrgvpqqtaallrfrkniinrsphvsesgpwiihcsagvgrtgiflvidamlrqak
LPDFIGVPRLLAKLREERFRAVQTEMQYLYAHRCVLE
. . . . |.| .||. ||.. |. .||
ekkvvdiynyvysieedrpyiiqtkdqyvfihqtile
|
|||||||||
| subfamily_Cele-PTP-19_pd | Subfamily Cele-PTP-19 | 225-444 | 7.5e-49 | 161.1 | In-house | 52-272 (301) | alignment | ||
Range on Protein: 225-444
Range on HMM: 52-272/301.0
TRNRYRNIPCCDITRVKLTDDP-HFYIHANLVSSGPNPRRFICTQAPLNGTIEEFWKMIIVTGIEYIVMLCELVEKGKPKSAEYFPSQIGQTTKIGRLCT
..|| ..|| | |.. .| |||| ... .|.|||.||.||. | |.|| |.. .| ||||.. ||| . | .||.|..|... .|||
dkhryptvPckPstavevivdGkrvPihanwiptsGhphrfiatqgPlkntsedfwamlvqydvekivmlgqkvekleekceeylpvkisekldigrfki
VTKESRVDIDKTLVMSTMRISKPGDNAVVKIVKHIHWRNWPDHGVPDNFLSPFRLLTVVKNCTKPIVVHCSAGVGRTGTLALILIILESICLPDFIGVPR
.|.. . ..| .. |... .. . | | . .|.|.||| | |. .||. ||||||||||.||. .. .. . | . .
kiknkelilnkkiskrtlevedstgkfatrtvthyqysewtdrgvPkshaelfdlmelvkksekPivvhcsaGiGrsvafigteylareveadptielte
LLAKLREERFRAVQTEMQYLY
|..|||.|...|||. | .
alkhlrehrwngvqtnsqlyw
|
|||||||||
| subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 225-380 | 8.8e-26 | 85.4 | In-house | 35-191 (297) | alignment | ||
Range on Protein: 225-380
Range on HMM: 35-191/297.0
TRNRYRNIPCCDITRVKLTDDP--HFYIHANLVS--SGPNPRRFICTQAPLNGTIEEFWKMIIVTGIEYIVMLCELVEKGKPKSAEYFPSQIGQTTKIGR
.||||.| | ||||| . . || |. | ... ..|..| ||. |...||... .. |||...| | |. | | |.|| .. | |
rknryrdilatddtrvkllrviterdyinadyvvfpdeeadlkyilaqGplsatvddfwtlvaeqdvrvivmvaklqedGrdkcapywpsvvqerlkagd
LCTVTKESRVDIDKTLVMSTMRISKPgdnAVVKIVKHIHWRNWPDHGVPDNFLSPFRLLT
. | | ...... ... . . |.|. . .||||||| .. |. .
vvveflsstsdefdrviltelqliyr...sesrvvrhvqflswpdhGvpsdledlvrfqa
|
|||||||||
| subfamily_CG7180_pd | Subfamily CG7180 | 226-453 | 1.3e-24 | 81.3 | In-house | 45-290 (296) | alignment | ||
Range on Protein: 226-453
Range on HMM: 45-290/296.0
RNRYRNIPCCDITRVKLT----DDPHFYIHANLVSSGPNPRRFICTQAPLNGTIEEFWKMIIVTGIEYIVMLCELVEKGKpKSAEYFPSQIgqTTKIGRL
.||. .. | .|| |. .. || | | | .. .| |.|| . |..|||... .|. .|.|.. . | . .|.| . .. | .
knrdvkvvPyDynRvvLekldGeeksdYinavyvdsflkkkeyivteapkketvdefWrlvydeeisavvvLtktfdfak.mypsywpnks..keqygei
C--TVTKESRVDIDKTLVMSTMR-----ISKPGDNAVVKIVKHIHWRNWPD-HGVPDN---FLSPFRLLTVV-KNC-----TKPIVVHCSAGVGRTGTLA
.|.... .. . . | . . . .| ..|||..... |. . || .. | .. .. ..|.||..| |..|.|
fveiveekqyanlkirtfkltkkivalteqekqvkaetRivklfqlteWeledkvPlstnalielrrrvrlwrekvdedpeegPvvvvssdGasRsGvyl
LILIILESICLPDFIGVPRLLAKLREERFRAVQTEMQYLYAHRCVLEYL
| . || . . . | . . .||..| . |.. .| | .||..
aidanlelvekeeevdvFeavktlrrsRpqLvenveeYkyiYdvlleav
|
|||||||||
| subfamily_CG42327_pd | Subfamily CG42327 | 226-377 | 9.4e-15 | 49.1 | In-house | 31-185 (319) | alignment | ||
Range on Protein: 226-377
Range on HMM: 31-185/319.0
RNRYRN---IPCCDITRVKLTD-DPHFYIHANLVSSG-PNPRRFICTQAPLNGTIEEFWKMIIVTGIEYIVMLCELVEKGKPKSAEYFPSQIGQ-TT-KI
..|. | .| .. . .| | .|..|. | | .|..|..|. . .||... || |..| |.| . |||.|.. . |
ksrvinvvPlPetrvvlqrigdddkdeyldasyvrGyddapnsyiaaqvsledsssdfwrtvweqqsrvivqltdlselGikvcaeylPtketldntsly
GRLcTVTKESRVDiDKTLVMSTMRISKpGDNAVVKIVKHIHWrNWPDHGVPDNFLSPFR
| . || | .. ..||. . . |. . . | . .|.. .|| . . .
Gdi.lvtlkgrev.kdryaistlllkr.vdkeesrelthywy.kwleaevPaeeaalia
|
|||||||||
| subfamily_Cele-PTP-17_pd | Subfamily Cele-PTP-17 | 235-296 | 2.2e-08 | 28.0 | In-house | 58-119 (347) | alignment | ||
Range on Protein: 235-296
Range on HMM: 58-119/347.0
CDITRVKLTDDPHFYIHANLVSSGPNPRRFICTQAPLNGTIEEFWKMIIVTGIEYIVMLCEL
. .. .||.. || | . . .| || || |. .||||. || . .| . |
peksknsraddvetyinashikfdnaskeyiltqyplpdtvrdfwkmvsvtkvtqvvtifep
|
|||||||||
| subfamily_Sponge-PTP-4_pd | Subfamily Sponge-PTP-4 | 238-310 | 6.2e-06 | 20.5 | In-house | 8-71 (130) | alignment | ||
Range on Protein: 238-310
Range on HMM: 8-71/130.0
TRVKltddPHFYIHANLVSSGPNPRRFICTQAPLNGTIEEFWKMIIVTGIEYIVMLCELVEKgkpksAEYFPS
.|.. . ||.|..| . . .. ||.|| | .||||.. .. .|.| . |. ||.|
srlq....gntyinasfvGllgrtaeylltqhpladtsmdfwkmmleryvnvlvvlgsveee.....deywpd
|
|||||||||
| 0046846 | (Phosphotyrosine protein) phosphatases II | 240-453 | 6.7e-38 | 125.5 | In-house | 5-173 (176) | alignment | ||
Range on Protein: 240-453
Range on HMM: 5-173/176.0
VKLTDDPHFYIHANLVSSGpnprRFICTQAPLNGTIEEFWKMIIVTGIEYIVMLCELVEKGKPKSAEYFPSQIGQTTkigrlctvtkesrvdidktlvms
. | . ||.|||. .. |.|.||.||..|...|..|. ||...|.|.|.||.|. | . |.| .
llgldldldyinanlilgs....rpiatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpeleklgi.......................
tmriskpgdnavvkivkHIHWRNWPDHGVPDNfLSPFRLLTVVKNCT---KPIVVHCSAGVGRTGTLALILIILEsiclPDFIGVPRLLAKLREERF-RA
.... .|||||||| ..|| .... .|..||||||.||||||...... .. | ||..|| |. .|
.................qylhlpwpDhgvpdl.elllellefirealkeggpvlVHCsaGigRtgtlvaayllel....ekglsveealalvreqRplga
VQTEMQYLYAHRCVLEYL
|||. || . ....|..|
vqtpeQyrflyefellll
|
|||||||||
| 0044763 | (Phosphotyrosine protein) phosphatases II | 241-456 | 2.6e-27 | 91.0 | In-house | 8-174 (178) | alignment | ||
Range on Protein: 241-456
Range on HMM: 8-174/178.0
KLTDDPH----FYIHANLVSSGpnprRFICTQAPlngtiEEFWKMIIVTGIEYIVMLCELVEKGKPKSAEYFPSQIGqttkigrlctvtkesrvdidktl
.|. .. .||.|. . | ..... | ....... || .||.|.| .| |..|. .|.|.. |
llsnleglersdyinaseilpg....lylgslpp.....addlellkelgithivnlteelelgflkcdpywpeeag.......................
vmstmriskpgdnavvkivKHIHWRNWPDHGVPDNFLSPFRLLTVVK----NCTKPIVVHCSAGVGRTGTLALILIILESiclpdFIGVPRLLAKLREER
. .. ..||||||| . .... .. .. .|..|||||||||.|||... .... . .. .. .|| |
...................iqylhipipDhgvpdllehflefvefieealdekggpvlVHCsaGvgRsgtlvaaylmkkl.....glsleeaielvrerR
FrAVQTEMQYLYAHRCVLEYLALK
. .|... |. . ... |..|. .
p.ivpnpgqlrqLyefelrllkes
|
|||||||||
| subfamily_Cele-PTP-1_pd | Subfamily Cele-PTP-1 | 243-469 | 1.7e-26 | 88.0 | In-house | 45-275 (290) | alignment | ||
Range on Protein: 243-469
Range on HMM: 45-275/290.0
TDDphfYIHANLVSSgPNPRRFICTQAPL-------NGTIEEFWKMIIVTGIEYIVMLCELVEKGKPKSA----EYFPSQIGQTTKIGRLcTVTKESRVD
.|| ||||| |. || |.| ||.|. | |||.|| |. .. .||||| || . .| .|.| ..|. |.. | || |..
ndd...yiHAnrvtc.pnglrliltqsPqekitekrnStiekfwwmakqEkvkqvVmlcefeeksantslfaCakYvpesvgeelkfkgl.tvkCkskek
iDKTLVMSTMRISKpgDNAVVKIVKHIHWRNWPDHGVPDNFLSPFRLLTVVKNCTKPIVVHCSAGVGRTGTLALILIILESIC-LPDFIGVPRLLAKLRE
.. . . .. . |. . |.| ..| . |... .. |. ||. . |..||| |. | .|| | . | . . . . .| .||.
.eddvetRelvvkf..ddeeeftvtHsllkgWnklnvqedtktllsliqkvkasktpvivHcvdGiSrsAalaaiilgyQkiaetsgsvkledvlkalrk
ERFRAVQTEMQYLYAHRCVLEYLALKKYVQSREDFAKFA
.| |....... .. .. .. . ..|.. | |
qralaitsalelafvdagivllaievldqfaeeetekka
|
|||||||||
| 0043147 | (Phosphotyrosine protein) phosphatases II | 244-446 | 2.8e-36 | 120.2 | In-house | 2-154 (172) | alignment | ||
Range on Protein: 244-446
Range on HMM: 2-154/172.0
DDPHFYIHANLVSSGPNPRRFICTQAPLNGTIEEFWKMIIVTGIEYIVMLCELvekgkpksaeyfpsqigqttkigrlctvtkesrvdidktlvmstmri
|... ||.|.... |.|||.||.||. |...||.|. || .||.|.||
degsdyinasyldlyyipdrfiatqgplrntladfwrmlkelgithivnltel...............................................
sKPGDNAVVKIVKHIHWRNWPDHGVPdNFLSPFRLLTVVKN-----CTKPIVVHCSAGVGRTGTLALILIILesiclpDFIGVPRLLAKLREERFRAVQT
... . .... .||||||| .. ..| ... .|..|||||||||||||......| . . .| .|| |. |||.
.lydpellerlgiqylylpwpDhgvp.llellleflefidellalspggpvlVHCsaGvgRtgtlvaaylml......lglsleeavalvrekRpgavqn
EMQYLYAH
. || . .
psqyrfly
|
|||||||||
| 0036282 | (Phosphotyrosine protein) phosphatases II | 248-446 | 4.7e-36 | 119.5 | In-house | 3-163 (174) | alignment | ||
Range on Protein: 248-446
Range on HMM: 3-163/174.0
FYIHANLVSSGPNPRRFICTQAPLNgtieeFWKMIIVTGIEYIVMLCELVEKGKPKSAEYFPSqigqttkigrlctvtkesrvdidktlvmstmriskpG
||.|. .. ..|.|..|.||. ||.|. ||...|||.|..|.|. | |.|.
dyinaspldlsyitprliagqgpla.....fwemlkelgittvvmlleekelglykcinywpe....................................l
DNAVVKIVKHIHWRNWPDHGVPDNFLsPFRLLTVVKNC-----TKPIVVHCSAGVGRTGTLALILIILESIClPDFIGVPRLLAKLREERFRAVQTEMQY
. .. . .... .|||||||| .... |... .|..|||||||||||||......| .. .... . .|...|| | ..|||. ||
redlerlgiqylylpwpDhgvpdlsi.llefvkfveealsedpggpvlVHCsaGvgRtGtlvaaylmlrgll.eslvdaldlvrelRlqrpgmvqtpsQy
LYAH
. .
rfly
|
|||||||||
| 0051429 | (Phosphotyrosine protein) phosphatases II | 249-469 | 2e-42 | 141.1 | In-house | 6-239 (272) | alignment | ||
Range on Protein: 249-469
Range on HMM: 6-239/272.0
YIHANLVSSGPN---PRRFICTQAPLNGTIEEFWKMiIVTGIEYIVMLCELVEKGKPKSAEYFP----------SQIGQTTKIGRLCTVTKESRVDIDKT
||.|. |. . |.|......||. |...||.. || .||.|....|.|. | | | . .| .|.|. . . . | .
yiNardvggygrvvkpgrlyrsggplpltaadfwrl.kelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseellldyi
LVMSTMRISKPGDNAvvKIVKHIHWRNWPDHGVPDNFlsPFRLLTVVKNcTKPIVVHCSAGVGRTGTLALILIILESICLPDFIG--------VPRLLAK
| . .... . ..| | |.|...|||||||.. .|| .. . .|..||||||..||||....|..|. ..| . . . . ...
lrellltlllsagea..revmhlhytdwpdhgvpqea..llellellld.ggpvlvHCsaGkdRTGtvvallllllgvsletivddYlltnlyleeavee
LREERFRAVQTEMQYLYAHRCVLEYlaLKKYVQSREDFAKFA
||. | |||||.|||. ....||. |... ..|... . |
lraqrpgavqteeqylflyeallel..lrsllsvraeyllaa
|
|||||||||
| 0051082 | (Phosphotyrosine protein) phosphatases II | 249-450 | 4.3e-28 | 93.2 | In-house | 5-150 (151) | alignment | ||
Range on Protein: 249-450
Range on HMM: 5-150/151.0
YIHANLVSSGpnprrFICTQAPLNgtieEFWKMIIVTGIEYIVMLCELVEKGkpKSAEYFPSQIgqttkigrlctvtkesrvdidktlvmstmriskpgd
||... | .| ......||. .|.... || .||.|....| | . .||.|..
yinfsyvtgg.....lyrsggpla....dflellkelgiktivnlrseeerg..ycpeylpelg....................................
navvKIVKHIHWRNWPDHGVPDNFLSPFRLLTVVKNC-TKPIVVHCSAGVGRTGTLALILIILESiclpdfIGVPRLLAKLREERFRAVQTEMQYLYAHR
|.||.. .|||.|.|..| . ..| .. .. .|..||||||.||||||......|. . . |. .|. |. .||...|.|. ..
....ievlhipildwpdpglplsfdavleflellldkkngpvlvHCsaGkgRTGtlvalylmllg......vsleealeeyrlkrpgvvqpnqqflfqlf
CVL
..|
all
|
|||||||||
| subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 249-308 | 1.6e-07 | 25.0 | In-house | 92-153 (349) | alignment | ||
Range on Protein: 249-308
Range on HMM: 92-153/349.0
YIHANLVSSG--PNPRRFICTQAPLNGTIEEFWKMIIVTGIEYIVMLCELVEKGKPKSAEYF
|| || .. ...|.||||| |...|.|.|. |.. .. | . |.. | |.
yinanylkltrisvekkyiatqaPlPstvddfykvillngvklvlsLnddkelslekcdiyw
|
|||||||||
| 0049260 | (Phosphotyrosine protein) phosphatases II | 260-446 | 2.8e-33 | 110.1 | In-house | 7-143 (152) | alignment | ||
Range on Protein: 260-446
Range on HMM: 7-143/152.0
NPRRFICTQAPLNGTIEEFWKMIIVTGIEYIVMLCELVEKGKPKSAEYFpsqigqttkigrlctvtkesrvdidktlvmstmriskpgdnavvkivkHIH
.|..||.||.|.. |...||.|. || .||||.||.|.||.| ..|. ...
mpfefiatqgpgpntladfwrmlkelgittivmltellelgklkceqyi................................................qyl
WRNWPDHGVPDNFLSPFRLLTVV----KNCTKPIVVHCSAGVGRTGTLALILIILesiclpDFIGVPRLLAKLREERFRAVQTEMQYLYAH
. .||||||||. || .. .. .|..|||||||||||||......| . . .| .|| | ||... |. . .
hlpwpDhgvpdlsqlllflllfieklaldkggpvlVHCsaGvgRtgtlvaaylml......lgvsleeavalvrekRpgavpnpgqlrfly
|
|||||||||
| subfamily_Nvec-PTP-3_pd | Subfamily Nvec-PTP-3 | 262-405 | 2.7e-12 | 41.3 | In-house | 4-153 (198) | alignment | ||
Range on Protein: 262-405
Range on HMM: 4-153/198.0
RRFICTQAPLNGTIEEFWKMIIVTGIEYIVMLCELVEKGKPKSAEYFPSQIGQTTKIGRLCTVTKESRVDIDKTLVMSTMRiSKPGDNAVVKIVKHIHWR
||.|.|| || |. .||.|. || .|||. . . . . |.|. |.| | |. .|| . | |.. . .. . . | .
rryiatqhplretladfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitalilt.nnttappstreishyqft
NWPDHGVPDNFL-----SPFRLLTVV--KNCTKPIVVHCSAGVGRTGTLAL
| .. |. | | .. .. |..|||| | | || .
swkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfva
|
|||||||||
| subfamily_Anemone-PTP-3_pd | Subfamily Anemone-PTP-3 | 262-405 | 2.9e-12 | 41.2 | In-house | 5-154 (199) | alignment | ||
Range on Protein: 262-405
Range on HMM: 5-154/199.0
RRFICTQAPLNGTIEEFWKMIIVTGIEYIVMLCELVEKGKPKSAEYFPSQIGQTTKIGRLCTVTKESRVDIDKTLVMSTMRiSKPGDNAVVKIVKHIHWR
||.|.|| || |. .||.|. || .|||. . . . . |.|. |.| | |. .|| . | |.. . .. . . | .
rryiatqhplretmadfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitalilt.nnttappstreishyqft
NWPDHGVPDNFL-----SPFRLLTVV--KNCTKPIVVHCSAGVGRTGTLAL
| .. |. | | .. .. |..|||| | | || .
swkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfva
|
|||||||||
| subfamily_Cele-PTP-7_pd | Subfamily Cele-PTP-7 | 269-461 | 7.1e-28 | 91.9 | In-house | 98-296 (302) | alignment | ||
Range on Protein: 269-461
Range on HMM: 98-296/302.0
APLNGTIEEFWKMIIVTGIEYIVMLCELVEKGKPKSAEYFPSQIGQTTKIGRLCTVTKESRVDID-----KTLVMSTMRISKPGD-NAVVKIVKHIHWRN
| . |.| .| .| . .| ||..||... | |||. ..|.. | || . |.. . |.. |.... |. | ..| | |. ...
vpkkstlekhwalieqynvaivvqlcsfvedeekkcaeyysdkvggelkfgrytvktvsvktdleeftdkksfklytveiknekkkkkvkktvdilafsa
WPDHGVPDNFLSPFRLLTVVKNCTKPIVVHCSAGVGRTGTLALILIILESICLPDFIGVPRLLAKLREERFRAVQTEMQYLYAHRCVLEYLALKKYVQS
||||| |.. . . .| . | ..||||||||||||| | .. . . .. .|. |. |||.| | .| || | |. |
wpdhGapkeaytaldilkfcesykknvlvhcsaGvGrtGtlvaikyGiqlcskkkvtdllsivlpvrqcryGavqdeqqliylllcvtkglmekagvly
|
|||||||||
| subfamily_hpo-7_pd | Subfamily hpo-7 | 272-478 | 6.7e-25 | 82.5 | In-house | 44-253 (263) | alignment | ||
Range on Protein: 272-478
Range on HMM: 44-253/263.0
NGTIEEFWKMIIVTGIEYIVMLCELVEKGKPKSAEYFPSQIGQTTKIGRLCTVTKESRVdidKTLVMSTMRISKPGDNAVVKIVKHIHWRNWPDHGVPDN
||..|...| |. | .||||. |.|. | .||| . . |. . .| .. ..|. . .| |. .. ||| .. |... | .
vqtidkfyqtivqtktevvvmLcDfneegvekcssyfPlekdekqklanvnvcttkvqs...dvllktlellstlgeKkkthtvkhysykgWiekndpel
FLSPFRLLTVVKNCtKPIVVHCSAGVGRTGTLALILIILE----SICLPDFIG--VPRLLAKLREERFRAVQTEMQYLYAHRCVLEYLALKKYVQSRE-D
. . ...| |..| |..|||||.|.||. ... .. |. . .. .|| .||..| ||..| || .. ||... . |
areilnilkvarns.kslvvhcstGiGrsaafsvaElvyqkmirsldttstveldylsLleelrssrkraihtPmqLafsilmvLdfvlnnfakgeleak
FAKFAKDYEQALAM
. . | | .| |
yqeirksylharqm
|
|||||||||
| subfamily_Cele-PTP-9_pd | Subfamily Cele-PTP-9 | 274-481 | 4.1e-26 | 86.6 | In-house | 40-247 (255) | alignment | ||
Range on Protein: 274-481
Range on HMM: 40-247/255.0
TIEEFWKMIIVTGIEYIVMLCELVEKGKPKSAEYFPSQIGQTTKIGRLCTVTKEsrvDIDKTLVMSTMRISKPGDNAVVKIVKHIHWRNWPDHGVPDNFL
|...|...|. |. | .||||.. |.|. | .||| . . |. . .| . . . .. .|. |. . ||| ... |... |..
tvdkfyqtivqtktevvvmlcdfaeegvekcssyfplekdeklkladvnvtttk...ssadvvlrtleitstlgekkkthtvkhysykGWieknaPelar
SPFRLLTVVKNCtKPIVVHCSAGVGRTGTLALILIILE----SICLPDFI--GVPRLLAKLREERFRAVQTEMQYLYAHRCVLEYLALKKyvQSREDFAK
.| ||.. |..|||||.|.||. ...|. .. |. . . .|| .||..| ||..| .| .. ||... |. . ... .
eilnilkvvrds.ksvvvhCstGiGrsaafvlaelvyqkmirsldttetveldylslleelrskrkraihtPlqlafsilmvldlvfpkg..eleakyqe
FAKDYEQALAMCPK
| | .| | |
irksylharqmmhk
|
|||||||||
| 0048076 | (Phosphotyrosine protein) phosphatases II | 345-452 | 1.2e-20 | 69.1 | In-house | 37-142 (145) | alignment | ||
Range on Protein: 345-452
Range on HMM: 37-142/145.0
KPGDNAVVKIVKHIHWRNWPDHGVPDNFLSPFRLLTVVKNC---TKPIVVHCSAGVGRTGTLALILIILEsiclpDFIGVPRLLAKLREERFRAVQTEMQ
. . ... . .... .|||||||| . ..| .... .|..|||||||||||||... ..|. . .. |...|. |. ||... |
tselellerlgiqylylpwpDhgvpdllellleflefieealkeggpvlVHCsaGvgRtgtlvaaylmll.....lgvsleealelvrsqrpgavpnpgq
YLYAHRCVLEY
. . ....||.
lrflyefelel
|
|||||||||
| 0048179 | (Phosphotyrosine protein) phosphatases II | 346-447 | 9.2e-20 | 66.3 | In-house | 48-139 (144) | alignment | ||
Range on Protein: 346-447
Range on HMM: 48-139/144.0
PgdnavvkiVKHIHWRNWPDHGVPDNFLSPFRLLTVVKNC---TKPIVVHCSAGVGRTGTLALILIILesicLPDfIGVPRLLAKLREERFRAVQTEMQY
. . .... .|||||||| . ..| .... .|..|||||||||||||... ... . . . . || .|. |. ||... |.
e........giqylhlpwpDhgvpdllellleflefieealeeggpvlVHCsaGvgRtgtlvaaylmk....klg.lsleealalvrsrrpgavpnpgql
LYAHR
. ..
rfLle
|
|||||||||
| subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 353-461 | 9.1e-14 | 45.6 | In-house | 89-202 (440) | alignment | ||
Range on Protein: 353-461
Range on HMM: 89-202/440.0
KIVKHIHWRNWPDHGVPDNFLSPFRLLTVV-----KNCTKPIVVHCSAGVGRTGTLALILIILESICLPDFIGVPRLLAKLREERFRAVQTEMQYLYAHR
. .|. |.. |||.||| .... | | |..||||||.|||| . . || | | . .. .|..| . ||| || . |
rtlkqyhyqgwpdkgvpkfagpvlkmiqdvnesqekagngpllvhcsagagrtgviiavdsilreakrsdqidifsfinsmrnnrpqmvqtpeqyafvhe
CVLEYLALKKYVQS
.||| | .
avlegllcgdtlil
|
|||||||||
| 0038934 | (Phosphotyrosine protein) phosphatases II | 354-409 | 1.2e-08 | 30.4 | In-house | 78-138 (194) | alignment | ||
Range on Protein: 354-409
Range on HMM: 78-138/194.0
IVKHIHWRNWPDHGVPDNFLSPFRLLTVV-----KNCTKPIVVHCSAGVGRTGTLALILII
... .||.|.. .. .| | .| .. . ..||| ||.||||||. .|
agieylklpfpddgtvPsleillrfldlvdeflnedpggvvaVHCkaGlgRtGtlvaaYLi
|
|||||||||
| PTPc_DSPc_SM00012 | 355-451 | 4.3e-29 | 96.2 | In-house | 2-105 (105) | alignment | |||
Range on Protein: 355-451
Range on HMM: 2-105/105.0
VKHIHWRNWPDHGVPDNFLSPFRLLTVVKNCTK------PIVVHCSAGVGRTGTLALILIILESICLP-DFIGVPRLLAKLREERFRAVQTEMQYLYAHR
|||.|. .|||||||.. | ..|| ||.... |.|||||||||||||.... |.|.... ... . ... .||..| ..||||.|||. .|
vkhyhytgwpdhgvPeesdsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgmvqteeqylflyr
CVLE
..||
alle
|
|||||||||
| 0048567 | (Phosphotyrosine protein) phosphatases II | 358-404 | 4.8e-06 | 21.0 | In-house | 40-95 (157) | alignment | ||
Range on Protein: 358-404
Range on HMM: 40-95/157.0
IHWRNWPDHGvPDNFLSPFRLLT-------VVKNCTKPIVVHCSAGV---GRTGTLA
... . |.| | | .|. . ..... |.|.|||.|| |||.||.
vyedfffdfG.PlnlailyrFilklnkflkilelagkaiavhckaglkkrgrtatLi
|
|||||||||
| PTEN_1 | 359-405 | 1.3e-07 | 26.6 | In-house | 98-149 (196) | alignment | |||
Range on Protein: 359-405
Range on HMM: 98-149/196.0
HWRNWPDHGVPDNFLSPFRLLTVVKNC-----TKPIVVHCSAGVGRTGTLAL
. . ..|||.|. . . . . ..||| ||.||.||..
lhfpieDhgapslselfdicksfiewllsdpngnvVlVHCkaGlgRsGtvva
|
|||||||||
| subfamily_CDKN3_pd | Subfamily CDKN3 | 359-447 | 6.6e-06 | 19.8 | In-house | 103-190 (202) | alignment | ||
Range on Protein: 359-447
Range on HMM: 103-190/202.0
HWRNWPDHGVPDN--FLSPFRLLTVVKNCTKPIVVHCSAGVGRTGTLALILIIlesiCLPDFIGVPRLLAKLREER-FRAVQTEMQYLYAHR
| .| .||| | . |.. . . .||| |.||. .. |.. | |.| ..|||. . ||.|| || | .
hhypiadglvpdiasclkileelrinlkayrktlvhcygglgrsslviaclll....ylddtiepkdaidklrdlkgsraiqtvkqynylse
|
|||||||||
| subfamily_PTPDC1_pd | Subfamily PTPDC1 | 362-443 | 3.3e-06 | 21.7 | In-house | 89-166 (182) | alignment | ||
Range on Protein: 362-443
Range on HMM: 89-166/182.0
NWPDHGVP--DNFLSPFRLLTVVKNCTkPIVVHCSAGVGRTGTLALILIILESIclpdfIGVPRLLAKLREERFRAVQTEMQYL
|.|.||. .. | .... . . . ||| || |||| | .. . . . . ..|..| ...|| |
gwkDygvasleriLdivkvvafalqeg.kvavhChaGlGrtGvliacylvyakr.....ltaekaiklvrskrpksiqtreqve
|
|||||||||
| subfamily_CDC14_pd | Subfamily CDC14 | 377-408 | 1.3e-06 | 22.5 | In-house | 254-285 (328) | alignment | ||
Range on Protein: 377-408
Range on HMM: 254-285/328.0
RLLTVVKNCTKPIVVHCSAGVGRTGTLALILI
..|....... |.||| ||.|||||| .
kfleiaekaeGaiavhCkaGLGrtGtLiacyl
|
|||||||||
| subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 384-457 | 1.8e-07 | 25.2 | In-house | 260-348 (350) | alignment | ||
Range on Protein: 384-457
Range on HMM: 260-348/350.0
NCTKPIVVHCSAGVGRTGTLALILIILESI-----CLPDF----------IGVPRLLAKLREERFRAVQTEMQYLYAHRCVLEYLALKK
. ..||.||||||||||||| . .|. . .. . .. .||. | . ||. |... . ..| | ||.|
arsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaaktrDlisiivnelrkqrismvqnldqfifiYeallfyfaLrk
|
|||||||||
| subfamily_CG42327_pd | Subfamily CG42327 | 385-453 | 1.9e-11 | 38.2 | In-house | 246-315 (319) | alignment | ||
Range on Protein: 385-453
Range on HMM: 246-315/319.0
CTKPIVVHCSAGVGRTGTLALILIILESICLP-DFIGVPRLLAKLREERFRAVQTEMQYLYAHRCVLEYL
|.||||| ||||||.. | ..|. . . .|.|. .|..| .||.| || . .. . ||
sqGPlvvhcsdGvGrtGlviasdiairsleeskrsvdiPqlvssvrrdrasavltkeqyefiykvlseya
|
|||||||||
| subfamily_Cele-PTP-17_pd | Subfamily Cele-PTP-17 | 385-457 | 8.5e-07 | 22.8 | In-house | 270-342 (347) | alignment | ||
Range on Protein: 385-457
Range on HMM: 270-342/347.0
CTKPIVVHCSAGVGRTGTLALILIILESICLPDFIGVPRLLAKLREERFRAVQTEMQYLYAHRCVLEYLALKK
|.|| | |. |. |. | ||.| . . |. |.|..| . | || |. | || ||
klapvvvmcdlgldrsatvvltsiiieqvldgktpdcddlfkkmrdqragvftmsifytyairaalfylklkl
|
|||||||||
| subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 385-457 | 7e-06 | 19.6 | In-house | 264-348 (349) | alignment | ||
Range on Protein: 385-457
Range on HMM: 264-348/349.0
CTKPIVVHCSAGVGRTGTLALILIILE--SICLPDF--IGVPR--------LLAKLREERFRAVQTEMQYLYAHRCVLEYLALKK
. ...|||||| ||||.| . ..|. . .. | .. . .|| |. || |. . ..|.|.||||
qlstllvhcsaGcGrtGvlvtldlllsileplqnesnkiklqallkDlisiivnelrkqrismvqnlaqfiaiyealLkyfalkk
|
|||||||||
| subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 387-451 | 1.5e-09 | 32.2 | In-house | 229-293 (297) | alignment | ||
Range on Protein: 387-451
Range on HMM: 229-293/297.0
KPIVVHCSAGVGRTGTLALILIILESICLPDFIGVPRLLAKLREERFRAVQTEMQYLYAHRCVLE
...|||||||||.| . | .||. . | .| .|||.| | ||| |. . . ||.
ayllvhcsaGvGrsGvvvlsdvilaklrkkripdvaailsilreqrarlvqtleqfellydavlk
|
|||||||||
| subfamily_Sponge-PTP-7_pd | Subfamily Sponge-PTP-7 | 389-457 | 2.9e-07 | 24.8 | In-house | 1-69 (69) | alignment | ||
Range on Protein: 389-457
Range on HMM: 1-69/69.0
IVVHCSAGVGRTGTLALILIILESICLPDFIGVPRLLAKLREERFRAVQTEMQYLYAHRCVLEYLALKK
.|||||.| |||||. |.. . | .. . . .| | | |..|.. | . | | | |
mvvhcssgtgrtgtfiaimvemarikseklvdifnnvqymrkcrpmmvmneieyifihdalvealklGk
|
|||||||||
| subfamily_Sponge-PTP7_pd | Subfamily Sponge-PTP7 | 390-457 | 1.4e-06 | 22.6 | In-house | 1-68 (69) | alignment | ||
Range on Protein: 390-457
Range on HMM: 1-68/69.0
VVHCSAGVGRTGTLALILIILESICLPDFIGVPRLLAKLREERFRAVQTEMQYLYAHRCVLEYLALKK
|||||.| |||||. |.. . | .. . . .| | | | .|.. | . | | | |
vvhcssGtGrtGtfiaimvemarikseklvdifnnvqymrkcrpmmvmneneymfihdalvealklGk
|
|||||||||