Gene DDB_G0283851 in Dictyostelium discoideum

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family DSP
Subfamily DdisDSP-sf1
Protein sequence
ID Type Fasta BLAST phosphatome Note
DdisP002_AA protein Get Run
DdisP002_AA_106-234 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_Dicty-DSP-Subfam1_pd Subfamily Dicty-DSP-Subfam1 107-234 3.8e-84 271.8 In-house 1-128 (128) alignment 
Range on Protein: 107-234
Range on HMM: 1-128/128.0
QTFFNANPQFGEFGTNVTLGDLWDPNFLPEHDVKSWALNLSDWQHDNLPYRIPFYRNILNSENDLPLVLYIHCECGCDRTGEVFASYAMKYLGYSFKEAM
||||||||||||||||||||||.|||.|||.|.|..||.||||..|.|||||..|||||.||..||||||.||||||||||||.|||.|||.||..|.|.
qtffnanpqfgefgtnvtlgdlidpnllpeddlkeyaltlsdwsadklpyrirdyrnillserelplvlyvhcecgcdrtgevlasyvmkykgydlkkal

EWDYSIAGRRIMINHQFAAQWYCYYLQV
||||.||||.|.|...|||||||.||||
ewdyaiagrdinisnrfaaqwyclylqv
0049772 (Phosphotyrosine protein) phosphatases II 107-231 4.5e-16 54.9 In-house 167-272 (314) alignment 
Range on Protein: 107-231
Range on HMM: 167-272/314.0
QtffnanpqfgefgtnvtlGDLWDPNFLPEHDVKSWALNLSDWQHDNLPYRIPFYRNILNSenDLPLVLYIHCECGCDRTGE-VFASYAMKYLGYSFKEA
.                  . |.||...... .| . ....|.. . | .   |.. |..   | . ....||  |..|||  |.| | ||.||.|..||
k..................eelydpelferlgikylripvpDgsaplledfdeflefieea..dkggpvlvHCkaGkgRtgtfvvaaylmkllgvsleea

MEWDYSIAGrrIMINHQFAAQ--WYCYY
.|.  ..    | .|. |  |   |...
ledvrlkRp..inpnpgfieqleqyefi
subfamily_Dicty-DSP19-1_pd Subfamily Dicty-DSP19-1 108-235 1e-83 270.4 In-house 1-128 (128) alignment 
Range on Protein: 108-235
Range on HMM: 1-128/128.0
TFFNANPQFGEFGTNVTLGDLWDPNFLPEHDVKSWALNLSDWQHDNLPYRIPFYRNILNSENDLPLVLYIHCECGCDRTGEVFASYAMKYLGYSFKEAME
|||||||||||||||||||||.|||.|||.|.|..||.||||..|.|||||..|||||.||..||||||.||||||||||||.|||.|||.||..|.|.|
tffnanpqfgefgtnvtlgdlidpnllpeddlkeyaltlsdwsadklpyrirdyrnillserelplvlyvhcecgcdrtgevlasyvmkykgydlkkale

WDYSIAGRRIMINHQFAAQWYCYYLQVA
|||.||||.|.|...|||||||.||||.
wdyaiagrdinisnrfaaqwyclylqvv
0048179 (Phosphotyrosine protein) phosphatases II 122-214 5.2e-12 41.2 In-house 33-125 (144) alignment 
Range on Protein: 122-214
Range on HMM: 33-125/144.0
NVTLGDLWDPNFLPEHDVKSWALNLSDWQHDNLPYRIPFYRNILNSENDLPLVLYIHCECGCDRTGEVFASYAMKYLGYSFKEAMEWDYSIAG
 ..| . ..|.||  . .. . |.. |..  .|.  ..   .....  . . . ..|| .|..||| . | | ||.||.|..||...  |.  
vinlteeyepefleregiqylhlpwpDhgvpdllellleflefieealeeggpvlVHCsaGvgRtgtlvaaylmkklglsleealalvrsrrp
0041856 (Phosphotyrosine protein) phosphatases II 123-233 3.9e-12 41.6 In-house 65-170 (182) alignment 
Range on Protein: 123-233
Range on HMM: 65-170/182.0
VTlGDLWDPNFLPEHDVKSWALNLSDWQHDNLPYRIPFYRNILNsendLPLVLYIHCECGCDRTGEVFASYAMKYLGYSFKEAMEWDYSIAGRRIMINHQ
.| ..| .|..|. . .. . |.  |.   .|.  . | . .|.     . . ..|| .|..||| . | | ||.||.|. ||...  |     . . .|
lt.eelywpellerlgiqylylpwpDhgvpdldelldfieevle....eggpvlVHCsaGvgRtgtlvaaylmkklgvsleeavklvrsrRpgmvitpnq

FAAQWYCYYLQ
.    ..... 
yfflqlallel
0038934 (Phosphotyrosine protein) phosphatases II 126-234 1.5e-09 33.3 In-house 67-176 (194) alignment 
Range on Protein: 126-234
Range on HMM: 67-176/194.0
GDLWDPNFLPEHDVKSWALNLSDW-Q---HDNLPYRIPFYRNILNSenDLPLVLYIHCECGCDRTGEVFASYAMKYLGYSFKEAMEWDYSIAGRRImINH
. ..||. .......   |   |       ..|   . .   .||   | . | ..||  |  ||| . |.| ...||.| .||...  .. .  | .| 
eryYdpeefekagieylklpfpddgtvPsleillrfldlvdeflne..dpggvvaVHCkaGlgRtGtlvaaYLiyrlgmsaeeAialfrekRpgai.pnq

QFAAQWYCYYLQV
..  ... .| ..
dyleallkrykel
0048076 (Phosphotyrosine protein) phosphatases II 128-231 2.2e-12 42.4 In-house 37-137 (145) alignment 
Range on Protein: 128-231
Range on HMM: 37-137/145.0
LWDPNFLPEHDVKSWALNLSDWQHDNLPYRIPFYRNILNSENDLPLVLYIHCECGCDRTGEVFASYAMKYLGYSFKEAMEWdysIAGRRIMINHQFAAQW
  ....| ..... . |.. |..  .|.  ..   .....  . . . ..||  |..||| . | | |..||.|. ||.|.   .  .| ...  .  . 
tselellerlgiqylylpwpDhgvpdllellleflefieealkeggpvlVHCsaGvgRtgtlvaaylmlllgvsleealel...vrsqrpgavpnpgqlr

YCYY
..|.
flye
0044763 (Phosphotyrosine protein) phosphatases II 128-232 3.8e-12 41.7 In-house 58-168 (178) alignment 
Range on Protein: 128-232
Range on HMM: 58-168/178.0
LW-------DPNFLPEHDVKSWALNLSDWQHDNLPYRIPFYRNILNSEN-DLPLVLYIHCECGCDRTGEVFASYAMKYLGYSFKEAMEWDYSIAGrrIMI
         || .. |....   ....|.   .|.  ..   .....   . . . ..|| .| .|.| . | | ||.||.|. ||.|.  .     |..
elelgflkcdpywpeeagiqylhipipDhgvpdllehflefvefieealdekggpvlVHCsaGvgRsgtlvaaylmkklglsleeaielvrerRp..ivp

NHQFAAQWYCYYL
|  .  | | ..|
npgqlrqLyefel
0051082 (Phosphotyrosine protein) phosphatases II 129-231 9.4e-15 50.0 In-house 48-150 (151) alignment 
Range on Protein: 129-231
Range on HMM: 48-150/151.0
WDPNFLPEHDVKSWALNLSDWQHDNLPYRIPFYRNILNSENDL-PLVLYIHCECGCDRTGEVFASYAMKyLGYSFKEAMEWDYSIAGRRIMINHQFAAQW
..|..|||.... . . . ||.  .||  .......|.  .|  . ....||  |..||| . | | |. ||.|. ||.|.  .. .  .  | ||  | 
ycpeylpelgievlhipildwpdpglplsfdavleflellldkkngpvlvHCsaGkgRTGtlvalylml.lgvsleealeeyrlkrpgvvqpnqqflfql

YCYY
....
fall
0036282 (Phosphotyrosine protein) phosphatases II 130-231 8.1e-09 30.9 In-house 61-164 (174) alignment 
Range on Protein: 130-231
Range on HMM: 61-164/174.0
DPNFLPEHDVKSWALNLSDWQHDNLPYRIPFYRNILNSEND-LPLVLYIHCECGCDRTGEVFASYAMKYLGY-SFKEAMEWDYSIAGRRIMINHQFAAQW
....| ..... . |.  | .  .|.  . |.. . .  ..    ....||  |..||| . | | |..... |. .|... ...   | ..   .    
lredlerlgiqylylpwpDhgvpdlsillefvkfveealsedpggpvlVHCsaGvgRtGtlvaaylmlrglleslvdaldlvrelRlqrpgmvqtpsQyr

YCYY
..||
flyy
0043147 (Phosphotyrosine protein) phosphatases II 131-209 1.2e-07 27.1 In-house 58-136 (172) alignment 
Range on Protein: 131-209
Range on HMM: 58-136/172.0
PNFLPEHDVKSWALNLSDWQHDNLPYRIPFYRNILN-SENDLPLVLYIHCECGCDRTGEVFASYAMKyLGYSFKEAMEWD
| .| ..... . |.  |    .| . . |.. | .   ..   . ..||  |..||| . | | |. ||.|. ||... 
pellerlgiqylylpwpDhgvpllellleflefidellalspggpvlVHCsaGvgRtgtlvaaylml.lglsleeavalv
0046846 (Phosphotyrosine protein) phosphatases II 135-232 6.5e-08 28.0 In-house 73-170 (176) alignment 
Range on Protein: 135-232
Range on HMM: 73-170/176.0
PEHDVKSWALNLSDWQHDNLPYRIPFYRNILNSENDlPLVLYIHCECGCDRTGEVFASYAMKY-LGYSFKEAMEWDYSIAGRRIMINHQFAAQWYCYYL
 ..... . |.  | .  .| . . ... | .  ..   . ..||  |. ||| . | | ...  |.|  ||...  ..  ...  . ..  . | ..|
eklgiqylhlpwpDhgvpdlelllellefirealke.ggpvlVHCsaGigRtgtlvaayllelekglsveealalvreqRplgavqtpeQyrflyefel
0040439 (Phosphotyrosine protein) phosphatases II 141-209 6.7e-09 31.2 In-house 142-221 (249) alignment 
Range on Protein: 141-209
Range on HMM: 142-221/249.0
SWALNLSDWQHDNLPYRIPFYRNILNSEND------LPLVLYIHCECGCDRTGEVFASYAM-----KYLGYSFKEAMEWD
 . ..  || ....|  ..   ....  ..       . ....||  |..||| . | | |     |.||....||... 
vlhiqytdwpdhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtfiaaylmleqlekelgvdleeavkll
0040438 (Phosphotyrosine protein) phosphatases II 142-218 7.5e-08 27.5 In-house 159-260 (317) alignment 
Range on Protein: 142-218
Range on HMM: 159-260/317.0
WALNLS----------------DWQHDNLPYRIPFYRNILNSENDL----PLVLYIHCECGCDRTGEVFASYAM-----KYLGYSFKEAMEWDYSIAGRR
. | ..                .| ....|. .    ..|.  ..     . .. .||  |..||| . | | |     |. |....||...  .  .  
rtlevedlgdsesrtvthfhytgWpdhgvppspdllldfleavrealedpggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpga

IM
. 
vq
0047943 (Phosphotyrosine protein) phosphatases II 143-209 7.6e-06 21.0 In-house 154-247 (273) alignment 
Range on Protein: 143-209
Range on HMM: 154-247/273.0
ALNLS----------------DWQHDNLPYRIPFYRNILNSEND------LPLVLYIHCECGCDRTGEVFASYAM-----KYLGYSFKEAMEWD
 | |.                .|  .. |  .    ....  ..       . . ..||  |. ||| . | . .     |. | ...||. . 
tleltnlgtgesrtvthfhytgwpdhgvppslesllefielvrkalealpsngpvvVHCsaGvgRtgtfialdllldqlekeggvdvleavkll
0051429 (Phosphotyrosine protein) phosphatases II 144-233 1e-07 27.4 In-house 125-223 (272) alignment 
Range on Protein: 144-233
Range on HMM: 125-223/272.0
LNLSDWQHDNLPYRIpfYRNILNSENDlPLVLYIHCECGCDRTGEVFASYAMKyLGYS--------------FKEAMEWDYSIAgRRIMINHQFAAQWYC
|   ||  .. |.    ....|.  .| .  ...||  |.|||| | | . .  || |                ||.|.  ..  . .  . .. .. | 
lhytdwpdhgvpqea..llellellld.ggpvlvHCsaGkdRTGtvvalllll.lgvsletivddYlltnlyleeaveelraqr.pgavqteeqylflye

YYLQ
..|.
alle
0036941 (Phosphotyrosine protein) phosphatases II 144-212 3.3e-06 22.1 In-house 157-255 (297) alignment 
Range on Protein: 144-212
Range on HMM: 157-255/297.0
LN----------------LSDWQHDNLPYRIPFYRNILNSEND------LPLVLYIHCECGCDRTGEVFASYAM--------KYLGYSFKEAMEWDYSI
|                   .| ....|  .  . ....  ..       . . ..||  |. |.| . | . |        |. |....||. .  . 
levtdtgngesrtvthfhytgwpdhgvpespaslldfielvrkvlkllpsggpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReq
0045450 (Phosphotyrosine protein) phosphatases II 145-208 1.1e-07 27.4 In-house 201-278 (307) alignment 
Range on Protein: 145-208
Range on HMM: 201-278/307.0
NLSDWQHDNLPYRIPFYRNILNSEND------LPLVLYIHCECGCDRTGEVFASYAMKYLG--------YSFKEAMEW
   .| ....|  .    ....  ..       . . ..||  |..||| . | | |....        ... ||...
hytgwpdhgvppsfeelldfieevrkaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkl
0039614 (Phosphotyrosine protein) phosphatases II 146-211 8.6e-08 27.5 In-house 190-266 (297) alignment 
Range on Protein: 146-211
Range on HMM: 190-266/297.0
LSDWQHDNLPYRIPFYRNILNSEND------LPLVLYIHCECGCDRTGEVFASYAM-----KYLGYSFKEAMEWDYS
  .| ... |  .    ..|.  ..       . . ..||  |..||| . | | |     |. |....||...  .
ytgwpdhgvppslellleflelvrealaelpkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelre
0043336 (Phosphotyrosine protein) phosphatases II 147-209 1.5e-07 26.6 In-house 181-252 (278) alignment 
Range on Protein: 147-209
Range on HMM: 181-252/278.0
SDWQHDNLPYRIPFYRNILNSEND----LPLVLYIHCECGCDRTGEVFASYAM-----KYLGYSFKEAMEWD
 .| ....|. .  . ..|.  ..     . ....||  |..||| . | | .     |..|... ||... 
lgwpdhgvpeslsllldflkavrealedsngpvlVHCsaGvgRTGtfialyllleqlekeggvdleeavkel
0042113 (Phosphotyrosine protein) phosphatases II 148-230 7.1e-09 30.9 In-house 150-238 (245) alignment 
Range on Protein: 148-230
Range on HMM: 150-238/245.0
DWQHDN-LPYRIPFYRNILNSEN-DLPLVLYIHCECGCDRTGEVFASYAM-----KYLGYSFKEAMEWDYSIAgRRIMINHQFAAQWYCY
| .  . | . . |.. ...  . | . ....||  |..||| . | | |     |.||.|. ||...  |   . .  . ..  . | .
dhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylmleqlekelgvsleeavkelrsqR.pgavqtpsqyrflyea
0037934 (Phosphotyrosine protein) phosphatases II 151-215 5.2e-08 28.2 In-house 152-222 (243) alignment 
Range on Protein: 151-215
Range on HMM: 152-222/243.0
HDNLPYRIPFYRNILNS-----ENDLPLVLYIHCECGCDRTGEVFASYAMKYL-GYSFKEAMEWDYSIAGR
...|   . . |.....      .|   ....||  |..||| . | | |..| |... ||...  .  . 
pedlldfldevrefieellsllaldsggpvlVHCsaGvgRtGtliaaylmllllgvdleeavkllreqRpg
DSPc Dual specificity phosphatase, catalytic domain 153-230 4.9e-09 31.2 Pfam-A 54-130 (133) alignment 
Range on Protein: 153-230
Range on HMM: 54-130/133.0
NLPYRIPFYRNILNSENDLPLVLYIHCECGCDRTGEVFASYAMKYLGYSFKEAMEWDYSIAgRRIMINHQFAAQWYCY
..   ..   .....  .     ..||..|  |.. . . | ||. ..| .||.|  .. .  .|. | .| .| . |
kiskeleeavefiekaeqkgkkvlVHCqaGisRSatliiaYlmktknlslneAyefvkerr.skispnagflrqLley
DSPc Dual specificity phosphatase, catalytic domain 153-230 4.9e-09 31.2 In-house 54-130 (133) alignment 
Range on Protein: 153-230
Range on HMM: 54-130/133.0
NLPYRIPFYRNILNSENDLPLVLYIHCECGCDRTGEVFASYAMKYLGYSFKEAMEWDYSIAgRRIMINHQFAAQWYCY
..   ..   .....  .     ..||..|  |.. . . | ||. ..| .||.|  .. .  .|. | .| .| . |
kiskeleeavefiekaeqkgkkvlVHCqaGisRSatliiaYlmktknlslneAyefvkerr.skispnagflrqLley
0045098 (Phosphotyrosine protein) phosphatases II 157-232 3.6e-07 25.3 In-house 178-269 (278) alignment 
Range on Protein: 157-232
Range on HMM: 178-269/278.0
RIPFYRNILNSE-------------NDLPLVLYIHCECGCDRTGEVFASYAMKYL---GYSFKEAMEWDYSIAGRRIMINHQFAAQWYCYYL
 . ... |..               .| . . ..||  |..||| . | | |..|   |... || ..  |  . ..  | ..  . | . |
flellefirealkllaslllsslllldsggpvlVHCsaGvgRtGtlvaaylmlelleggvdlleavkelrsqRpglavqnleqyrflyefll
0048567 (Phosphotyrosine protein) phosphatases II 161-231 7.5e-07 23.7 In-house 63-135 (157) alignment 
Range on Protein: 161-231
Range on HMM: 63-135/157.0
YRNILNSENDLPLVLYIHCECGC---DRTGEVFASYAMKYLGYSFKEAMEWDySIAGRRIMINHQFAAQWYCYY
  ..|.. .  . ....||  |     ||. . ..|....||..  ||...  .|.   ... ..    .. |.
lnkflkilelagkaiavhckaglkkrgrtatLigcYlilhlgftpeeaiapl.rivrpgsvpfrdasyllslyn
PTPc_motif_SM00404 163-230 9.8e-09 30.2 In-house 72-137 (140) alignment 
Range on Protein: 163-230
Range on HMM: 72-137/140.0
NILNSENDLPLVlYIHCECGCDRTGEVFASYAMKYLGYSFKEAMEWDYSIAgRRIMINHQFAAQWYCY
 | |.|..   | ..|| .|  |.. . . | |.| ..| .||.|   . .  .|. | .| .| . |
fienaekkggkv.lVHCqaGvSRSatliiaYlmryrqlslaeayefvkerR.piispnlnfvrqLiey
0049260 (Phosphotyrosine protein) phosphatases II 168-212 2.1e-07 26.3 In-house 85-128 (152) alignment 
Range on Protein: 168-212
Range on HMM: 85-128/152.0
ENDLPLVLYIHCECGCDRTGEVFASYAMKyLGYSFKEAMEWDYSI
  |   . ..||  |..||| . | | |. ||.|..||...  . 
aldkggpvlVHCsaGvgRtgtlvaaylml.lgvsleeavalvrek
subfamily_MSG5_pd Subfamily MSG5 174-208 3.5e-06 20.2 In-house 101-135 (165) alignment 
Range on Protein: 174-208
Range on HMM: 101-135/165.0
VLYIHCECGCDRTGEVFASYAMKYLGYSFKEAMEW
 . .||.||  |.  .  .| ||| . |...| . 
kilvhcqcglsrsaslivayimkyynlslrdaydk
subfamily_DSP12_pd Subfamily DSP12 175-231 9.3e-07 23.4 In-house 85-140 (155) alignment 
Range on Protein: 175-231
Range on HMM: 85-140/155.0
LYIHCECGCDRTGEVFASYAMKYLGYSFKEAMEWdYSIAGRRIMINHQFAAQWYCYY
...||. |  |   . . | ||. . |...|..   . . ..|  |. | .|   ..
vlvHCqagvSRSvtiviAYlmkkeklslekAlkl.vkekkpeiepNegFleQLklfe