Gene dupA in Dictyostelium discoideum

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family DSP
Subfamily DSP-unclassified
Protein sequence
ID Type Fasta BLAST phosphatome Note
DdisP015_AA protein Get Run
DdisP015_AA_2128-2273 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
OmpH Outer membrane protein (OmpH-like) 260-302 6.5e-07 17.4 Pfam-A 60-102 (158) alignment
Range on Protein: 260-302
Range on HMM: 60-102/158.0
QQQKQNSQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQK
|....| |....|. ...........|...|. |...|| |..
qkeqknlqseraqlsaeeekakeeelqakeqelqayaqqlqae

Pkinase Protein kinase domain 1731-2026 3.3e-31 98.3 Pfam-A 2-257 (260) alignment
Range on Protein: 1731-2026
Range on HMM: 2-257/260.0
KDLKRVAKGAYGTVYKGTLGNDEGlEIAVKLMPVPKTIHDRCVL--YdiftEILIMDTFrSDSRGCHMFDYGVDGENYWIVMKSYKC-SLKEWrLKQTLP
. |... .|..|.|||..  ...  ..||| .  ... ..           |. |. .. . .  ......  . .....|.. ... .| .. ||.  .
elleklGsGsfGkVykakekktgk.kvAvKilkkeeekskkektalr....Elkilkkl.nHpnivkllevfeekdelylvleyveggdlfdl.lkkkgk

FleLLPLLLNIFTNVLQSVQFLGDHKINHFDIKCDNFLVHplKKGTIeedfwnqptndpnfavCLADWGEAKVYtQDVEGYTTRNRGTEFIKSPEMLTia
.      . .|....|.....| ...| | |.| .|.|..  .||..                ..||.| ||.. .  .. .|   ||.   .||.|   
l..seeeikkialqilegleylHsngiiHrDLKpeNiLld..ekgel................kiaDFGlakkl.eksseklttlvgtreYmAPEvll..

yasqktrenfdrrKKVGSNTASDVWSLGCLFYELLTGDFLFYDDDWVKFFIRVTQPGQELITPERKSKVANIPAILDYLDYVFIRDPFYRPTLRDLLTK
             |. .  ...||||||...||||||...|....  .   .. .  .. .  .....  . . . | .. .. .||  |.|....|..
.............kakeytkkvDvWslGvilyelltgklpfsgeseedqlelirkilkkkleedepkssskseelkdlikkllekdpakRltaeeilkh

Pkinase_Tyr Protein tyrosine kinase 1734-2023 1.8e-15 46.7 Pfam-A 5-255 (259) alignment
Range on Protein: 1734-2023
Range on HMM: 5-255/259.0
KRVAKGAYGTVYKGTLG---NDEGLEIAVKLMpvpKTIHDRCVLYDIFTEILIMDTFrSDSRGCHMFDYGVDGENYWIVMKSYKCS-LKEwRLKQT-LPF
|....||.|.|..|||    ... ...||| .   |  ...    ....|. || .. . ..  ..    ...|...||..  .   |..  |...  . 
kklGeGafGeVvegtlkgekekkevkVavKtl...keeaeeeekeefleeakimkkl.khenivkllgvctkeepllivteyvegGdLlk.fLrkkekek

LELLPlLLNIFTNVLQSVQFLGDHKINHFDIKCDNFLVHPlkkgtieedfwnqptndpNFAVCLADWGEAKVYTQDvEGYTTRNRGTEFIK--SPEMLTI
|.|   ||.. ... . ...| ..|. | |. . | |..                   |  | ..| | |.  ..| . |.......  .|  .||.|. 
ltled.llsfalqiAkGmeyLeskklvHrdLaarNvLlee..................nkvvkisDfGLardiekd.dyykkkekaklpvkWmapEslke

AYasqktrenfdrrkkvgSNTASDVWSLGCLFYELLTGDFLFYDDDWVKFFIRVTQPGQELITPERKSKvanipAILDYLDYVFIRDPFYRPTLRDL
                   ...||||| | | .|..|     | .   . ...  . |..| .||  ..      . . .   . ..|  |||...|
kk................ftsksDvWsfGvllwEiftlgespypglsneevleklkegkrlekpencpe.....elyelmkqCweeepekRptfkel

0044763 (Phosphotyrosine protein) phosphatases II 2125-2272 1.8e-29 98.0 In-house 17-173 (178) alignment
Range on Protein: 2125-2272
Range on HMM: 17-173/178.0
RFYMDRPSKVASFMYISSFNPSMNKNMLiNEYQITHIINCTGS--------PNAFPDH--FEYLHLQLHDQPHQDITQSLSLAFDFIRDAI-VHHGKVLI
|...  .|..  ..|..|..|......|  |. ||||.|.|.         .  .|.   ..|||. ..| . .|... .  ...||..|.  ..|.||.
rsdyinaseilpglylgslppaddlell.kelgithivnlteelelgflkcdpywpeeagiqylhipipDhgvpdllehflefvefieealdekggpvlV

CSDKGVSRSSALAIGYFMDSRSISYFEAFILVRDCRYiISPNTGFVEQLCRWGKQRRNF
.   ||.|| .|.. | | ....|..||. ||| .|  |.|| |...||... .. .. 
HCsaGvgRsgtlvaaylmkklglsleeaielvrerRp.ivpnpgqlrqLyefelrllke

0045098 (Phosphotyrosine protein) phosphatases II 2127-2267 8.1e-18 60.2 In-house 18-269 (278) alignment
Range on Protein: 2127-2267
Range on HMM: 18-269/278.0
YMDRPSKVASFMYISSFN-----------------------------------------PSMNKNMLInEYQITHIINC---------------------
 .  ||..  ..|.....                                          . . .||  |..||.|...                     
llgipseitpalylgnldknRykdilpydhsrVkdYINAsyidgypkkfIatqgPlpstvadfwrmlw.elgitvivmltelvelgrekcaqywpeggsl

--------------------------------TGSPNAFPDHFEYLHLQLHDQPHQDITQSLSLAFDFIRDAIV--------------HHGKVLICSDKG
                                .. ....  |. ||.   |. |...|..|.  ...|||.|.               ..|.||.    |
tygdftvtllseevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllsslllldsggpvlVHCsaG

VSRSSALAIGYFMDSR---SISYFEAFILVRDCRYI-ISPNTGFVEQLCRWGK
|.|. .|.. | | ..    ....||.  .| .| . . .| .. ..|...  
vgRtGtlvaaylmlelleggvdlleavkelrsqRpglavqnleqyrflyefll

subfamily_Slingshot_pd Subfamily Slingshot 2128-2264 1.2e-23 77.4 In-house 16-152 (169) alignment
Range on Protein: 2128-2264
Range on HMM: 16-152/169.0
MDRPSKVASFMYISSFNPSMNKNMLiNEYQITHIINCTGS-PNAFPDHFEYLHLQLHDQPHQDITQSLSLAFDFIRDAIVHHGKVLICSDKGVSRSSALA
.|..||.  ..|. |   . | . | .| ....|.| |    | ||..||||.....|....|. .    ...||. |  .. |||.   .|||||..  
ldsaskifdhvylGsewnasnleel.kengveyilnvtkeidnffpekfeylnirvydeeetdllkywnetykfiekakkkgskvlvhckmGvsrsastv

IGYFMDSRSISYFEAFILVRDCRYIISPNTGFVEQLCR
| | | . ..|. ||.  |.. | .| ||.||..||  
iayamkeyglsleealeyvkerrsvikPnkgflkqlee

subfamily_DSP6_pd Subfamily DSP6 2128-2268 3.4e-23 75.9 In-house 11-153 (158) alignment
Range on Protein: 2128-2268
Range on HMM: 11-153/158.0
MDRPSKVASFMYISSFNPSMNKNMLiNEYQITHIINCTGS-PNAFPD--HFEYLHLQLHDQPHQDITQSLSLAFDFIRDAIVHHGKVLICSDKGVSRSSA
   | .. ...|. | . . | ..| ....| ...| |   ||.| .  ...||.. ..|. .|.... .  |..|| .|  .. |||.    |.||| .
aefpveilpllylGsakdasnlevl.kklkikyvlnvtsnlpnkfeesgelkylqipiedhlsqnlakffPeaiefidearskkskvlvhClaGisrsvt

LAIGYFMDSRSISYFEAFILVRDCRYIISPNTGFVEQLCRWGKQ
... |.| .. .|  .|. ||.. .  ||||  |..||  . ..
vtlaylmkklalslndaydlvkkrksnisPnfnfmgqlldfers

subfamily_Dicty-DSP19-like_pd Subfamily Dicty-DSP19-like 2129-2271 2.7e-75 244.9 In-house 1-154 (154) alignment
Range on Protein: 2129-2271
Range on HMM: 1-154/154.0
DRPSKVASFMYISSFNPSMNKnMLINEYQITHIINC-TGSPNAFPDH---------FEYLHLQLHDQPHQDITQSLSLAFDFIRDAI--VHHGKVLICSD
||.||.|.|.|||||....|| .......|..|.|. .|..|.|.|.         .|||.|.|.|....||...|..||.||.|||  |...|||..||
drnskeaiflyissfdaalnk.ldlqlkniksilnvgiGinnlftdensdindgfiieylnlelfddvnfdiiekldkafefiddaiggvennkvlvhsd

KGVSRSSALAIGYFMDSRSISYFEAFILVRDCRYIISPNTGFVEQLCRWGKQRRN
||||||.||.|.|.||...||...|..|..|.||||.||.||..||....|....
kGvsrsaallisylmdklkislslalellkdsryiikPnqGflkqleifekellf

subfamily_DSP1_pd Subfamily DSP1 2129-2269 3.3e-36 118.8 In-house 16-156 (163) alignment
Range on Protein: 2129-2269
Range on HMM: 16-156/163.0
DrPSK-VASFMYISSFNPSMNKNMLINeYQITHIINCTG-SPNAFPDHFEYLHLQLHDQPHQDITQSLSLAFDFIRDAIVHHGKVLICSDKGVSRSSALA
| |.. .  |.|. | . . |...| .  .||.|.|...  .|.|.|.||| .|.|.|.|..||.. .. . .|| ... ..|||||  . |.||||.| 
d.PvekildfLylGsetvasnleiLks.lgitailnvskeldnvfedlfeYkklkleDspkadislvfeeviefidevkkknGkvlihCqaGisRsstlc

IGYFMDSRSISYFEAFILVRDCRYIISPNTGFVEQLCRWGKQR
. |.| .. .|. ||| .|.. |.|||||.||| || .. |. 
laylmktkrvsleeafdfvkqrRsiisPnagFvlqLlnyekkl

0041856 (Phosphotyrosine protein) phosphatases II 2130-2270 1.4e-22 75.6 In-house 18-173 (182) alignment
Range on Protein: 2130-2270
Range on HMM: 18-173/182.0
RPSKVASFMYISSFNP--------------SMNKNMLINEyQITHIINCTgSPNAFPDHF-----EYLHLQLHDQPHQDitqsLSLAFDFIRDAIVHHGK
 ....    |..|. .               .. .|| .. .||.|.|.| ... .|...     .||.|.  | .  |    |. ..|||.... ..|.
dldyInanlylgslpatrfiatqgpllstvadflrmlkel.gittivnlt.eelywpellerlgiqylylpwpDhgvpd....ldelldfieevleeggp

VLICSDKGVSRSSALAIGYFMDSRSISYFEAFILVRDCRY--IISPNTGFVEQLCRWGKQRR
||.    ||.|. .|.. |.| ....|..||. ||| .|   .|.|| .|..||. . ....
vlVHCsaGvgRtgtlvaaylmkklgvsleeavklvrsrRpgmvitpnqyfflqlallellll

subfamily_DSP8_pd Subfamily DSP8 2130-2268 5.3e-20 65.6 In-house 14-153 (159) alignment
Range on Protein: 2130-2268
Range on HMM: 14-153/159.0
RPSKVASFMYISSFNPSMNKNMLiNEYQITHIINCTGSPN--AFPDHFEYLHLQLHDQPHQDITQSLSLAFDFIRDAIVHHGKVLICSDKGVSRSSALAI
.| ..  ..|. | . ......| ... |....|   |     .  . ..|.. ..|. . .. . .  ...||  |  ..|.||.    | |||...||
gptrilknlylGsqkdvlseell.sklgisyvlnasnscpkleelkeskflrvPvkDkydekllpwfdksvefidkaksengrvlvhvlaGisrsatvai

GYFMDSRSISYFEAFILVRDCRYIISPNTGFVEQLCRWGKQ
.| |   ..|. ||.  |.. |  ||||  |..||  . |.
ayimktlemsldeayrfvkekrptispnlnflgqLleyeke

subfamily_DSP10_pd Subfamily DSP10 2131-2268 9.4e-29 94.3 In-house 14-152 (159) alignment
Range on Protein: 2131-2268
Range on HMM: 14-152/159.0
PSKVASFMYISSFNPSMNKNMlINEYQITHIINCTG-SPNAFPD-HFEYLHLQLHDQPHQDITQSLSLAFDFIRDAIVHHGKVLICSDKGVSRSSALAIG
 |.| .|... | . . .... .....||...| |  .|| | . ...| .....|. .|.. |    |..|| .|  .  .||.    |.|||....|.
asqvlpfLflGsekdaadlda.ldrlnitavlnvttsvPnefeeealkYkripvsDtskqnlkqyfeealefieearkkgsrvLvhCqaGisrsatvvia

YFMDSRSISYFEAFILVRDCRYIISPNTGFVEQLCRWGKQ
| |  ...|  .|. .|...| ||||| .|. || .. |.
YlmkhlnlslndaykfvkekrpiisPnLnfmGqLlefeke

PTPc_motif_SM00404 2131-2267 9.9e-28 91.8 In-house 2-139 (140) alignment
Range on Protein: 2131-2267
Range on HMM: 2-139/140.0
PSKVASFMYISSFNPSMnKNMLINEYQITHIINCTGSPN--AFPDHFEYLHLQLHDQPHQDITQSLSLAFDFIRDAIVHHGKVLICSDKGVSRSSALAIG
||..   .|..| . .. .  |.....|||.||.| . .      .|..|...|.|.  ..... |. . |||..|.  .||||.    ||||| .|.| 
psrilphlylgskskaq.npallkklgithvinvteevsltkensgfqilqiplddnekdklskyldkvldfienaekkggkvlVHCqaGvSRSatliia

YFMDSRSISYFEAFILVRDCRYIISPNTGFVEQLCRWGK
| |..|..|. ||. .|.. | |||||..||.||. . |
YlmryrqlslaeayefvkerRpiispnlnfvrqLieyek

0048076 (Phosphotyrosine protein) phosphatases II 2131-2268 8.7e-24 79.3 In-house 4-141 (145) alignment
Range on Protein: 2131-2268
Range on HMM: 4-141/145.0
PSKVASFMYISSFNPSMNKNMLiNEYQITHIINC-TGSPNAFPDHFEYLHLQLHDQPHQDITQSLSLAFDFIRDAIVHHGKVLICSDKGVSRSSALAIGY
||..   .|..|.   ..  .|  ...||...|. .  .. .. ...||.| . | . .|... |  ...||..|. ..|.||..   ||.|. .|.. |
pseilpglylgslptaldlell.kdlgittvlnltselellerlgiqylylpwpDhgvpdllellleflefieealkeggpvlVHCsaGvgRtgtlvaay

FMDSRSISYFEAFILVRDCRYIISPNTGFVEQLCRWGKQ
 | ....|..||. ||| .| .. || |....|... ..
lmlllgvsleealelvrsqrpgavpnpgqlrflyefele

0048179 (Phosphotyrosine protein) phosphatases II 2131-2267 4.8e-23 76.9 In-house 4-142 (144) alignment
Range on Protein: 2131-2267
Range on HMM: 4-142/144.0
PSKVASFMYISSFNPSMNKNMLiNEYQITHIINCTGSPNAFPDH---FEYLHLQLHDQPHQDITQSLSLAFDFIRDAIVHHGKVLICSDKGVSRSSALAI
||.. . .|..|.  ...  .|  ...||..||.| .          ..|||| ..| .  |... |  ...||..|. ..|.||..   ||.|. .|..
pseilpglylgslptaldlell.kklgittvinlteeyepefleregiqylhlpwpDhgvpdllellleflefieealeeggpvlVHCsaGvgRtgtlva

GYFMDSRSISYFEAFILVRDCRYIISPNTGFVEQLCRWGK
 | |  . .|..||. ||| .|... || |....|....|
aylmkklglsleealalvrsrrpgavpnpgqlrfLleyek

subfamily_LRR-DSP_pd Subfamily LRR-DSP 2131-2267 3.2e-22 72.9 In-house 120-256 (263) alignment
Range on Protein: 2131-2267
Range on HMM: 120-256/263.0
PSKVASFMYISSFNPSMNKNMLiNEYQITHI-INCTGSPNAFPDHFEYLHL-QLHDQPHQDITQSLSLAFDFIRDAiVHHGKVLICSDKGVSRSSALAIG
|...   ... . . ..||..| .. ..||| .  .     ||. | || . ...| .. || | .     || .   ..| ||.    ||||||.| | 
PdeiidklflGgldsannksil.kdlgvthillavadfePlfPklfkylsiddiedvdeadisqhfeetnafieeG.rkkGGvlvhcraGvsrsstlvis

YFMDSRSISYFEAFILVRDCRYIISPNTGFVEQLCRWGK
|.|  ... . ||. ||   |  | ||.||..|| .. |
ylmkkqrlkfkealdlvikkrpriqPnpGfkdqlkkyek

subfamily_DSP14_pd Subfamily DSP14 2132-2271 9.8e-28 91.1 In-house 8-146 (157) alignment
Range on Protein: 2132-2271
Range on HMM: 8-146/157.0
SKVASFMYISsfNPSMNKNMLINEYQITHIINCT-GSPNAFPDHFEYLHLQLHDQPHQDITQSLSLAFDFIRDAIVHHGKVLICSDKGVSRSSALAIGYF
|.... ...|    . ... |.....||.|||.|   ||   ...|.......|.|...... .  . | |...  ..||.|.    ||||| .|.. | 
sqitpsLfls..gvaalskellkkkkitliinvtvelpntklkdiervkvpveDnpeaklakhfdevadkieevkkkggktlvhCvaGvSRSAslclayl

MDSRSISYFEAFILVRDCRYIISPNTGFVEQLCRWGKQRRN
|  ...|  ||. ||...| ||.||.|| .|| .. |. ..
mkyeklsLreayklvksaRpiirPNvGFwkqlidyEkklkg

subfamily_DSP15_pd Subfamily DSP15 2132-2269 3e-25 83.1 In-house 3-139 (151) alignment
Range on Protein: 2132-2269
Range on HMM: 3-139/151.0
SKVASFMYISSFNPSMNKNMLiNEYQITHIINCTGSPNAFPDHFEYLHLQLHDQPHQDITQSLSLAFDFIRDAIVHHGKVLICSDKGVSRSSALAIGYFM
|||   .|.. |. | ....| .| .||||..   ... . ...||. ... | |...... .. . .|| .. .. ..||.    |||||  |.. |.|
skvlpglylgnfrdskdeelL.keknithilsvhdnakkllkdieYkciaasDtpsaklskffkesvefihkcRlkeenvlvhClaGvsRsvtlvvaYlm

DSRSISYFEAFILVRDCRYIISPNTGFVEQLCRWGKQR
   .... .|.  .. .| .  ||.|| .||  . |..
tvtelnwrdalevikaaRsvanPnfGfkrqlkeyektk

subfamily_DSP19_pd Subfamily DSP19 2133-2268 1.2e-33 110.7 In-house 14-149 (152) alignment
Range on Protein: 2133-2268
Range on HMM: 14-149/152.0
KVASFMYISSFNPSMNKNMLiNEYQITHIINCT-GSPNAFPDHFEYLHLQLHDQPHQDITQSLSLAFDFIRDAIVHHGKVLICSDKGVSRSSALAIGYFM
.|   .|..| .  ..|..| .| .||||.| . | ||.||..|.||.... |.| .|... |. |.|||..|  ..| ||.  . |||||....|.|.|
eveprlylgsqdvaadkeil.kekkitHilnvatgvpnvfpkdftylsieilDlpetdllsylkealdFieearskdgavlvHCnAGvSRsasvviaylm

DSRSISYFEAFILVRDCRYIISPNTGFVEQLCRWGKQ
 ....|. ||. |||. |  |.||.||..||... ..
kkeelsleealelvrearpcikPneGFikqLkeyeae

subfamily_DSP12_pd Subfamily DSP12 2133-2268 3.4e-23 76.7 In-house 4-142 (155) alignment
Range on Protein: 2133-2268
Range on HMM: 4-142/155.0
KVASFMYISSFNPSMNKnMLINEYQITHIINCTGSP----NAFPDHFEYLHLQLHDQPHQDITQSLSLAFDFIRDAIVHHGKVLICSDKGVSRSSALAIG
..   .|... .. ...  | .|..|||..  .  .    .. . . .....|. |.|..|| . |  |.||| .|. ..|.||.    |||||... | 
rilpglylggleavqee.ellkelkithvlsvikeelpehklkkgkvstkfiqilDepeediLshldeavdFieealeeegavlvHCqagvSRSvtiviA

YFMDSRSISYFEAFILVRDCRYIISPNTGFVEQLCRWGKQ
|.| .  .|  .|. ||.. .  |.||.||.|||  . | 
YlmkkeklslekAlklvkekkpeiepNegFleQLklfekm

subfamily_DSP3_pd Subfamily DSP3 2133-2268 1.9e-22 73.6 In-house 13-156 (162) alignment
Range on Protein: 2133-2268
Range on HMM: 13-156/162.0
KVASFMYISSFNPSMNKNMLiNEYQITHIINCTGS--------PNAFPD-HFEYLHLQLHDQPHQDITQSLSLAFDFIRDAIVH-HGKVLICSDKGVSRS
 |   .|..  . ...|. | ..  |||..|.. .        .. . | ...|| |...|.|. |. .  . |..||..|. . .||||. . .|||||
evypklyvgdeavakdkskL.kklGithvlnaaegrfskvdtgaefykdleikylGlevdDvpefdlskyFetaakfidealsqkegkvlvhcvvGvsRs

SALAIGYFMDSRSISYFEAFILVRDCRYIiSPNTGFVEQLCRWGKQ
..|.. | | .|...  ||   ||. | |  ||.||..||.   ..
atlvlayLmirrkmtlveairtvrkkRei.lPneGFlkqLaeldee

0051082 (Phosphotyrosine protein) phosphatases II 2133-2262 6.1e-13 44.1 In-house 10-146 (151) alignment
Range on Protein: 2133-2262
Range on HMM: 10-146/151.0
KVASFMYISSFNPSMNKNMLiNEYQITHIINCTG------SPNAFPD-HFEYLHLQLHDQPHQDITQSLSLAFDFIRDAIVH-HGKVLICSDKGVSRSSA
 | ...|.|..  . . ..|  |..|..|.|...       |. .|.  .|.||....| | ... .|.  . .|.. .. . .|.||.    |..|. .
yvtgglyrsggpladflell.kelgiktivnlrseeergycpeylpelgievlhipildwpdpglplsfdavleflellldkkngpvlvHCsaGkgRTGt

LAIGYFMDsRSISYFEAFILVRDCRY-IISPNTGFVEQL
|.. | |  . .|..||.  .| .|  .. ||..|. ||
lvalylml.lgvsleealeeyrlkrpgvvqpnqqflfql

subfamily_STYXL1_pd Subfamily STYXL1 2134-2268 1.1e-21 70.7 In-house 15-152 (157) alignment
Range on Protein: 2134-2268
Range on HMM: 15-152/157.0
VASFMYISSFNPSMNKNmLINEYQITHIINCTGS----PNAFPDHFEYLHLQLHDQPHQDITQSLSLAFDFIRDAIVHHGKVLICSDKGVSRSSALAIGY
. ...|.  .. ..|.. . .. ..   .| .       .. .|  . ||....|... |. . |. | .|| .   .   ||. |.||.||| |..|.|
lPgklylGnykqaqnpa.ikkdlkvkahvnvsmdadkliagvadvakllhiavedeneadllerlkeavqfiekhkkegevvlvfsnkGisrsaaviiay

FMDSRSISYFEAFILVRDCRYIISPNTGFVEQLCRWGKQ
.| |. |.. .|.  ...|.  . || .||||| .| ||
lmyskkitlkkaykylkkCkenvkPnrafveqlseWekq

0043147 (Phosphotyrosine protein) phosphatases II 2134-2273 3.5e-19 64.6 In-house 22-164 (172) alignment
Range on Protein: 2134-2273
Range on HMM: 22-164/172.0
VASFMYISSFNPSMNKNMLiNEYQITHIINCTG----SPNAFPDHFEYLHLQLHDQPHQdITQSLSLAFDFIRD--AIVHHGKVLICSDKGVSRSSALAI
.  . .  ... ... .||  |..||||.|.|.     .. ..  ..||.|   |.. . ... |  ...||..  |.  .|.||.    ||.|. .|..
fiatqgplrntladfwrml.kelgithivnltellydpellerlgiqylylpwpDhgvp.llellleflefidellalspggpvlVHCsaGvgRtgtlva

GYFMDsRSISYFEAFILVRDCRYIISPNTGFVEQLCRWGKQRRNFK
 | |  ...|..||. |||..| ....| ..  .|. . |.....|
aylml.lglsleeavalvrekRpgavqnpsqyrflyyfeklllllk

0040438 (Phosphotyrosine protein) phosphatases II 2134-2265 1.2e-15 53.0 In-house 31-271 (317) alignment
Range on Protein: 2134-2265
Range on HMM: 31-271/317.0
VASFMYISSFNPSMNKNML--------------------------------------------------------INEYQITHIINCTGSPNA-------
  . . ....  ...||                                                          . |...|.|.. | .          
kldtysvaelpenkdknrypdilpydhsRVkLsplggdldsdYInAsyvdgpnlkrkfIatqgPlpntvedFwrmvweqgvtvivmLteleelgrekcaq

---------------------FPDHFEYLHLQLHDQ----------------PHQDITQSLSLAFDFIRDAIVH----HGKVLICSDKGVSRSSALAIGY
                       .......|.. |                 |.... .|..| .||.. .  .    .|.||. .  ||.|. .... |
YwplgetltygdftvtllseeelagitlrtlevedlgdsesrtvthfhytgWpdhgvppspdllldfleavrealedpggpvlVHCsaGvgRtGtfiaay

FM-----DSRSISYFEAFILVRDCRYIISPNTGFVEQLCRW
 |       . ....||.  .| .|. . .. .. ..|...
lmleqlekeggvdveeavkelreqRpgavqtpeqyrflyda

subfamily_Choan-DSP_MKP-1_pd Subfamily Choan-DSP_MKP-1 2135-2268 9.3e-23 74.4 In-house 12-146 (148) alignment
Range on Protein: 2135-2268
Range on HMM: 12-146/148.0
ASFMYISSFNPSMNKNMlINEYQITHIINCTGS-PNAFPDH-FEYLHLQLHDQPHQDITQSLSLAFDFIRDAIVHHGKVLICSDKGVSRSSALAIGYFMD
 .|... | .  .. .. ...  .|.|.|.| . .||. ..  ||||..|.|.|..|. .    . .|.| |  . ..||.    |||||||||. ...|
dafLFlGskksaadlea.lkalgvtrivnatkerdnaldqrgieYlhvaldDkpkedlsaiFediiafvrkakdeGrrvLvhlqmGvsrssalallwlid

SRSISYFEAFILVRDCRYIISPNTGFVEQLCRWGKQ
 . .|  ||. ||.. |  . || ||..||  . ..
fkrvslkealalvkskrryvdpnlgfLkqLaeleqa

0036282 (Phosphotyrosine protein) phosphatases II 2135-2267 9.1e-13 43.7 In-house 16-167 (174) alignment
Range on Protein: 2135-2267
Range on HMM: 16-167/174.0
ASFMYISSFNPSmnKNMLINEYQITHIINCTGSPN----------------AFPDHFEYLHLQLHDQPHQDITQsLSLAFDFIRDAIVH--HGKVLICSD
 .  .....  .     .. |..||...... .                    . ...||.|   |    |... |  ...|...|. .  .|.||.   
tprliagqgpla..fwemlkelgittvvmlleekelglykcinywpelredlerlgiqylylpwpDhgvpdlsi.llefvkfveealsedpggpvlVHCs

KGVSRSSALAIGYFMDSRSI-SYFEAFILVRDCR---YIISPNTGFVEQLCRWGK
 ||.|. .|.. | |  . . |. .|. ||| .|     . .. .. ..|  ..|
aGvgRtGtlvaaylmlrglleslvdaldlvrelRlqrpgmvqtpsQyrflyyfek

0043336 (Phosphotyrosine protein) phosphatases II 2136-2264 2.4e-11 39.1 In-house 35-271 (278) alignment
Range on Protein: 2136-2264
Range on HMM: 35-271/278.0
SFMYISSFNPSMNKNML--------------------------------------------------------INEYQITHIINCTGSPN----------
  ..|. .  ...||                                                          . |...|.|.. |.             
dtysiallpenkdknrykdilpydhsrvklsllggdldsdYinAsyvdgynvprkfiatqgPlpetvedFwrmvwelgvttivmLtelvelgrvkcaqYw

---------------------------------AFPDHFEYLHLQLHDQPHQDITQSLSLAFDFIRDAIV----HHGKVLICSDKGVSRSSALAIGYFM-
                                   .  .. .|.. .. |....  |||| .||.....      .|.||. .  ||.|. .... | . 
pggsltygdftvtllkeehlddytvrtlevtnlgdgesrtvthyhylgwpdhgvpeslsllldflkavrealedsngpvlVHCsaGvgRTGtfialylll

----DSRSISYFEAFILVRDCRYIISPNTGFVEQLCR
    . . ....||.  .| .|. . ..  . ..|..
eqlekeggvdleeavkelreqRpgavqtpsqyrflye

subfamily_MKPLT_pd Subfamily MKPLT 2139-2266 4e-24 79.0 In-house 30-157 (164) alignment
Range on Protein: 2139-2266
Range on HMM: 30-157/164.0
YISSFNPSMNKNMlINEYQITHIINCT-GSPNAFPDHFEYLHLQLHDQPHQDITQSLSLAFDFIRDAIVHHGKVLICSDKGVSRSSALAIGYFMDSRSIS
|    . . |... ... .||||.| . .  .|||  .||| ....|.... ... |  | .|. |||   |.||.   .|.||||. .. . . |.   
ylGnakhatnekv.lkdlkithivnvsqekkdafpksveYlqvkvedesdeqlssfleraakfladaidsGGrvlvhcvqGksrsssvtvafLikskgwt

YFEAFILVRDCRYIISPNTGFVEQLCRWG
. ||.  ... | |..|| ||. ||... 
lkeayeylkerrsivapnrGflkqlakfe

subfamily_MKPLV_pd Subfamily MKPLV 2139-2266 4e-24 79.0 In-house 30-157 (164) alignment
Range on Protein: 2139-2266
Range on HMM: 30-157/164.0
YISSFNPSMNKNMlINEYQITHIINCT-GSPNAFPDHFEYLHLQLHDQPHQDITQSLSLAFDFIRDAIVHHGKVLICSDKGVSRSSALAIGYFMDSRSIS
|    . . |... ... .||||.| . .  .|||  .||| ....|.... ... |  | .|. |||   |.||.   .|.||||. .. . . |.   
ylGnakhatnekv.lkdlkithivnvsqekkdafpksveYlqvkvedesdeqlssfleraakfladaidsGGrvlvhcvqGksrsssvtvafLikskgwt

YFEAFILVRDCRYIISPNTGFVEQLCRWG
. ||.  ... | |..|| ||. ||... 
lkeayeylkerrsivapnrGflkqlakfe

0045450 (Phosphotyrosine protein) phosphatases II 2142-2265 1.3e-17 59.9 In-house 51-299 (307) alignment
Range on Protein: 2142-2265
Range on HMM: 51-299/307.0
SFNPSMNKNM-----------------------------------------------------------------LINEYQITHIINCTGSPNA------
..  ...||                                                                  .. |...|.|...|..         
llpenkdknrykdilpydhtRVklssldgsledsdYiNAsyvrvpllllldgydlkrkfIatqgPlpetvedFwrmlweqgvtvivmltelvelgrekca

-----------------------FPDHFEYLHLQLHDQ-----------------PHQDITQSLSLAFDFIRDAIV------HHGKVLICSDKGVSRSSA
                         |.. ...| ..|                  |.... .|.. ..|||. .         .|.||. .  ||.|. .
qywPdegeeltygnftvtllseehldgytvrtlevtdldgtgesrtvthfhytgwpdhgvppsfeelldfieevrkaleelpkggpvlVHCsaGvgRtGt

LAIGYFMDSRS--------ISYFEAFILVRDCRYIISPNTGFVEQLCRW
... | | ..         ....||. |.|..|. . .| .. ..|...
fiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrflyea

0049260 (Phosphotyrosine protein) phosphatases II 2145-2268 1.8e-16 55.6 In-house 22-148 (152) alignment
Range on Protein: 2145-2268
Range on HMM: 22-148/152.0
PSMNKNMLiNEYQITHIINCTGSPN----AFPDHFEYLHLQLHDQPHQDITQSLSLAFDFIRD-AIVHHGKVLICSDKGVSRSSALAIGYFMDsRSISYF
 . ...||  |..||.|...|         .. ...||||.  | . .|..| |  ...||.  |.  .|.||.    ||.|. .|.. | |  . .|..
ladfwrml.kelgittivmltellelgklkceqyiqylhlpwpDhgvpdlsqlllflllfieklaldkggpvlVHCsaGvgRtgtlvaaylml.lgvsle

EAFILVRDCRYIISPNTGFVEQLCRWGKQ
||. ||| .| .. || |. ..|  . |.
eavalvrekRpgavpnpgqlrflyefekl

0046846 (Phosphotyrosine protein) phosphatases II 2146-2267 1.2e-17 59.7 In-house 36-170 (176) alignment
Range on Protein: 2146-2267
Range on HMM: 36-170/176.0
SMNKNMLINEYQITHIINCTGS--------PNAFPD----HFEYLHLQLHDQPHQDItQSLSLAFDFIRDAIVHHGKVLICSDKGVSRSSALAIGYFMDS
 ..   .. |..||...|.|          || .|.    ...||||   |    |. . |  ...|||.|. ..|.||.    |..|. .|.. | . .
ladflemlkelgitavvnlteevelgrlkcpnywpeleklgiqylhlpwpDhgvpdl.elllellefirealkeggpvlVHCsaGigRtgtlvaayllel

-RSISYFEAFILVRDCRY-IISPNTGFVEQLCRWGK
 . .|..||. |||..|   . .. .....| .. .
ekglsveealalvreqRplgavqtpeQyrflyefel

DSPc Dual specificity phosphatase, catalytic domain 2147-2267 6.2e-26 85.8 Pfam-A 10-132 (133) alignment
Range on Protein: 2147-2267
Range on HMM: 10-132/133.0
MnkNMLINEYQITHIINCT-GSPN---AFPDHFEYLHLQLHDQPHQDITQSLSLAFDFIRDAIVHHGKVLICSDKGVSRSSALAIGYFMDSRSISYFEAF
.    |.....||..||.|   ||     . ..|||.....|.  ..|.. |. | .||..|.  ..|||.    |.||| .|.| | |.....|. ||.
s..lalleklgitlvinvtkevpnnnaikkseieylripvedetetkiskeleeavefiekaeqkgkkvlVHCqaGisRSatliiaYlmktknlslneAy

ILVRDCRYIISPNTGFVEQLCRWGK
 .|.. | .||||.||. ||. . .
efvkerrskispnagflrqLleyer

DSPc Dual specificity phosphatase, catalytic domain 2147-2267 6.2e-26 85.8 In-house 10-132 (133) alignment
Range on Protein: 2147-2267
Range on HMM: 10-132/133.0
MnkNMLINEYQITHIINCT-GSPN---AFPDHFEYLHLQLHDQPHQDITQSLSLAFDFIRDAIVHHGKVLICSDKGVSRSSALAIGYFMDSRSISYFEAF
.    |.....||..||.|   ||     . ..|||.....|.  ..|.. |. | .||..|.  ..|||.    |.||| .|.| | |.....|. ||.
s..lalleklgitlvinvtkevpnnnaikkseieylripvedetetkiskeleeavefiekaeqkgkkvlVHCqaGisRSatliiaYlmktknlslneAy

ILVRDCRYIISPNTGFVEQLCRWGK
 .|.. | .||||.||. ||. . .
efvkerrskispnagflrqLleyer

PTEN_1 2148-2264 8.1e-12 40.4 In-house 56-186 (196) alignment
Range on Protein: 2148-2264
Range on HMM: 56-186/196.0
NKNMLINEYQ--ITHIINCTGSPN----------AFPDHFEYLHLQLHDQPHQDITQSLSLAFDFIRDAI--VHHGKVLICSDKGVSRSSALAIGYFMDS
. ..| | ..  ||...| .  ..          .|  ..||||.   | . ... . .  . .||  ..   ....||.    |..||  ... | | .
vaadldnlkedgitlvvnlseeeelsgrsydleeffksgveylhfpieDhgapslselfdicksfiewllsdpngnvVlVHCkaGlgRsGtvvaayLmyk

RSISYFEAFILVRDCRYIISPNTGFVEQLCR
.  .. ||. |||..|  ..||... |.| .
gkltadeAlelvrekRppgapnspsqerlle

subfamily_STYX_pd Subfamily STYX 2149-2265 3.2e-22 72.4 In-house 31-153 (166) alignment
Range on Protein: 2149-2265
Range on HMM: 31-153/166.0
KNMLINEYQITHIINCTGSPNA------FPDHFEYLHLQLHDQPHQDITQSLSLAFDFIRDAIVHHGKVLICSDKGVSRSSALAIGYFMDSRSISYFEAF
|   ...  ||||.    ...|      |||.| || |.. |.. ..| . |    .|| |.. . ||||.  . |.|||.|| |.|.|..  . | |||
klevlkkhgithivcirqnieanlikpnfpdrfrylvldvadntveniirylptvkefiddslqkggkvlvhgnagisrsaalviayimetyglkyreaf

ILVRDCRYIISPNTGFVEQLCRW
  |.. |. |.|| |||.||  .
ayvqerrfcinpnegfvsqlkey

0037934 (Phosphotyrosine protein) phosphatases II 2149-2265 1.4e-14 49.7 In-house 64-237 (243) alignment
Range on Protein: 2149-2265
Range on HMM: 64-237/243.0
KNMLINEYQITHIINCTG----------------------------------------------SPNAFPDHFEYLHLQLHD----QPHQDITQSLSLAF
   .. |..||.|...|                                                .. .  .. |..|   |    . ..|. . |. . 
fwrmlwelgitvivmltelvElgrekcaqywpgevtygdftvtllseehlddytvrtlllenldlddltrlvihyhylpwpdhgvPdspedlldfldevr

DFIRD-----AIVHHGKVLICSDKGVSRSSALAIGYFMDSR-SISYFEAFILVRDCRYI-ISPNTGFVEQLCRW
.||..     |. ..|.||.    ||.|. .|.. | | .. .....||. |.|..|   . .. .. ..| ..
efieellsllaldsggpvlVHCsaGvgRtGtliaaylmllllgvdleeavkllreqRpgkavqtpsqyrflyea

0049772 (Phosphotyrosine protein) phosphatases II 2151-2269 3.7e-21 71.6 In-house 165-273 (314) alignment
Range on Protein: 2151-2269
Range on HMM: 165-273/314.0
MLIneyqithiiNCTGSPNAFPDH-FEYLHLQLHDqPHQDITQSLSLAFDFIRDAiVHHGKVLICSDKGVSRSS-ALAIGYFMDSRSISYFEAFILVRDC
.|          ... .|. |... ..||.. . | ....... .  ...||..|   .|.||..   |..|.  .....| |  . .|. ||.  || .
llk.........eelydpelferlgikylripvpD.gsaplledfdeflefieea.dkggpvlvHCkaGkgRtgtfvvaaylmkllgvsleealedvrlk

RYiISPNTGFVEQLCRWGKQR
|. |.|| ||.|||... .. 
Rp.inpnpgfieqleqyefil

0039614 (Phosphotyrosine protein) phosphatases II 2151-2265 8.8e-12 40.5 In-house 119-284 (297) alignment
Range on Protein: 2151-2265
Range on HMM: 119-284/297.0
MLINEYQITHIINCTGSPNA-------FPD---------------------------------HFEYLHLQLHDQPHQDITQSLSLAFDFIRDAIV----
 .. |...|.|.. |            .|.                                  ... |.| .. |. .. .||.| ..|.. .      
rmvweqgvtvivmLtklvelgrkcaqywpeeggtygdftvtllkvehldgytvrtlevtnngesrtvthfqytgwpdhgvppslellleflelvrealae

--HHGKVLICSDKGVSRSSALAIGYFM-----DSRSISYFEAFILVRDCRYIISPNTGFVEQLCRW
   .|.||. .  ||.|. .... | |       . ....||.  .| .|. . .. .. ..|...
lpkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavqtpsqyrflyda

0040439 (Phosphotyrosine protein) phosphatases II 2152-2265 1.7e-18 62.6 In-house 73-241 (249) alignment
Range on Protein: 2152-2265
Range on HMM: 73-241/249.0
LINEYQITHIINCTGSPN--------------------------------------------AFPDHFEYLHLQLHDQPHQDITQSLSLAFDFIRDAIV-
.. |..||.|...|                                                 .......||.| .| |.... .|.. ..|||. .   
mlwelgitvivmLtslvelgrekcaqywplggsleygdftvtllsvevkddytvrtleltnlydgesrtvlhiqytdwpdhgvppsfedlldfieavrka

-----HHGKVLICSDKGVSRSSALAIGYFM-----DSRSISYFEAFILVRDCRYIISPNTGFVEQLCRW
      .|.||. .  ||.|. .... | |       . ....||. |.|..|. . .| .. ..|...
leelpkggpvlVHCsaGvgRtGtfiaaylmleqlekelgvdleeavkllrsqRpgavqnpeqyrflyea

0036941 (Phosphotyrosine protein) phosphatases II 2152-2265 3.6e-14 48.2 In-house 97-272 (297) alignment
Range on Protein: 2152-2265
Range on HMM: 97-272/297.0
LINEYQITHIINCTGSPNA------------------------------------------------FPDHFEYLHLQLHDQPHQDITQSLSLAFDFIRD
.. |...|.|.. |                                                      .....  |.. .. |. .. .| .  .|||. 
mvweqnvtvIvmltelvelgrekcaqywpleegesltygdftvtllsvevvllddytlrtlevtdtgngesrtvthfhytgwpdhgvpespaslldfiel

AIV------HHGKVLICSDKGVSRSSALAIGYFM--------DSRSISYFEAFILVRDCRYIISPNTGFVEQLCRW
.         .|.||. .  ||.|| .... . |          . ....||.  .|..|. . .. .. ..|...
vrkvlkllpsggpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyea

0042113 (Phosphotyrosine protein) phosphatases II 2152-2265 2.1e-12 42.5 In-house 71-238 (245) alignment
Range on Protein: 2152-2265
Range on HMM: 71-238/245.0
LINEYQITHIINCTGSPN--------------------------------------------AFPDHFEYLHLQLHDQPHQDITQSLSLAF---DFIRDA
.. |..||.|...|                                                  . ..| .|.. .. |..... .|.| .   .|.|.|
mlwelgittivmLteeeelgrvkcaqywplgesltygdftvtllseehlddytvrtlevtnlgddesrevihyhylpwpdhgvpdllellldflefvrka

IV--HHGKVLICSDKGVSRSSALAIGYFM-----DSRSISYFEAFILVRDCRYIISPNTGFVEQLCRW
.    .|.||. .  ||.|. .... | |       . .| .||.  .|..|. . .. .. ..| ..
laedsngpvlVHCsaGvgRtGtfiaaylmleqlekelgvsleeavkelrsqRpgavqtpsqyrflyea

subfamily_Sponge-DSP-Subfam1_pd Subfamily Sponge-DSP-Subfam1 2152-2270 8.8e-07 22.1 In-house 19-142 (145) alignment
Range on Protein: 2152-2270
Range on HMM: 19-142/145.0
LINEYQITHIINCT-----GSPNAFPDHFEYLHLQLHDQPHQDITQSLSLAFDFIRDAIVHHGKVLICSDKGVSRSSALAIGYFMDSRSISYFEAFILVR
...|  |. |.| .      | ..  ...| | .  .|    |..| .    |||         |..    ||||| .... ..|   ...  ||   ||
tlqelgisrivnmaagslvasqelksesieillitaedlesydlsqhfdevtdfidkgkeegagvfvhcmagvsrsvtvsvaflmkycnmtlseaarqvr

DCRYIISPNTGFVEQLCRWGKQRR
  |    ||  |. .| .  || .
snrllaypnvtflknllnlekqlk

0047943 (Phosphotyrosine protein) phosphatases II 2153-2263 1.9e-10 36.1 In-house 97-265 (273) alignment
Range on Protein: 2153-2263
Range on HMM: 97-265/273.0
INEYQITHIINCTGSPN-----------------------------------------------AFPDHFEYLHLQLHDQPHQDITQSLSLAFDFIRDAI
. |.....|.  |   .                                                ... ... |.. .. | ... .||.  ..||... 
vweqnvrviVmLtelvelgrekcaqYwpleggelsltygkftvtllseetkddytvrtleltnlgtgesrtvthfhytgwpdhgvppslesllefielvr

V------HHGKVLICSDKGVSRSSALAIGYFM-----DSRSISYFEAFILVRDCRYIISPNTGFVEQLC
       ..|.|.. .  ||.|. .... . .       . ....||. |.|..|. . ..  . ..|.
kalealpsngpvvVHCsaGvgRtgtfialdllldqlekeggvdvleavkllrsqRpgmvqtpeqyrfly

0051299 (Phosphotyrosine protein) phosphatases II 2153-2255 4.7e-09 31.6 In-house 112-271 (288) alignment
Range on Protein: 2153-2255
Range on HMM: 112-271/288.0
INEYQITHIINCTGS------------------------------------------------PNAFPDHFEYLHLQLHDQPHQDITQSLSLAFDFIRDA
. |.....|.  |.                                                 ..    .... |.. .. |.... .|..| .||.|..
vweqnvrvIvmltklvelgrekcaqYwplggsltygditvtllseevlddytvrtlevtnldlldgdgesrtvthfhytnwpdhgvpdspellldflrlv

IVH----HGKVLICSDKGVSRSSALAIGYFM-----DSRSISYFEAFILVRDCRYIISPN
. .    .| |.. .  ||.|. .... . .       . ....||.  .| .|. . ..
rkalasgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlreqRpgmvqt

subfamily_PTPMT1_pd Subfamily PTPMT1 2153-2264 4.5e-07 24.5 In-house 54-163 (171) alignment
Range on Protein: 2153-2264
Range on HMM: 54-163/171.0
INEYQITHIINCTGSPNAFpdHFEYLHLQLHDQPHQDITQSLSLAFDFIRDAIVHHGKVLICSDKGVSRSSALAIGYFMDSRSISYFEAFILVRDCRYII
 .||..... |.| . .      |.|.|.  |  ..  ...|. . .||.. . .  .| .    | .||..|.. | | .. .|  ||   ....| ||
neeyelkalansteewkkl..gveqlqlatvDfteapdleklekgvefiekvaskgkrvYvHCkaGrgRsatlvacylmkkeklspeeAlkalkkkRkii

SPNTGFVEQLCR
  ..  ...| .
rlakkqwkalqe

0046845 (Phosphotyrosine protein) phosphatases II 2155-2251 5.5e-07 24.7 In-house 99-255 (284) alignment
Range on Protein: 2155-2251
Range on HMM: 99-255/284.0
EYQITHIINCTGSPNA----------------------------------------------FPDHFEYLHLQLHDQPHQDITQSLSLAFDFIRDAIVH-
|.....|.  |.  .                                                  ...  |.. .. |.... .|..  ..|.|..  . 
eqnvrvIVmltelvengrekcaqYwplegevltygdftvtllseevkddytvrtleltnlgytgesrtvthfhytswpdhgvppspedlleflrlvrell

-----HGKVLICSDKGVSRSSALAIGYFMDSR--------SISYFEAFILVRDCRYI
     .|.... .  ||.|. .... . . ..         ....||.  .|..|. 
enlpgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpg

0038934 (Phosphotyrosine protein) phosphatases II 2156-2269 7.6e-07 24.5 In-house 55-176 (194) alignment
Range on Protein: 2156-2269
Range on HMM: 55-176/194.0
YQITHIINCTG-SPNAFPDHFEYLHLQLHDQPHQDIT--QSLSLAFDFIRDAIVHH-----GKVLICSDKGVSRSSALAIGYFMDSRSISYFEAFILVRD
......|. |  ..   |..|| . .. .. |  |     ||.. ..|.. . ...     |.|..    |..|.  |.. | . .. .|. ||  |.|.
vklglvidltnteryYdpeefekagieylklpfpddgtvPsleillrfldlvdeflnedpggvvaVHCkaGlgRtGtlvaaYLiyrlgmsaeeAialfre

CRYIISPNTGFVEQLCRWGKQR
.|  . || ...|.|... |. 
kRpgaipnqdyleallkrykel

subfamily_MSG5_pd Subfamily MSG5 2175-2267 2.3e-09 30.6 In-house 68-158 (165) alignment
Range on Protein: 2175-2267
Range on HMM: 68-158/165.0
FEYLHLQLHDQphQDITQSLSLAFDFIRDAIVHHGKVLICSDKGVSRSSALAIGYFMDSRSISYFEAFILVRDCRYIISPNTGFVEQLCRWGK
 .| |.. . .    |.. ||     |  |  .. |.|.  . |.|||..| . | |   ..|  .|. ...     |||. |.. ||  |. 
vkyyhiewehd..skivkdlsrltriihaatskrkkilvhcqcglsrsaslivayimkyynlslrdaydklksvaddispsiglifqlmewev