Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
---|---|---|---|---|---|---|---|---|---|
Myotub-related | Myotubularin-like phosphatase domain | 527-866 | 9.3e-118 | 386.0 | Pfam-A | 2-351 (353) | alignment | ||
Range on Protein: 527-866
Range on HMM: 2-351/353.0
LFAFKYSPNKSQLQD---GWRILNDFGEWLRQGILSETAgynmkWRYSEKNIEY-INPTYPKWLVVPHNISDEEVGICMNFRSKGRIPALSWIS-RDGVP
|.||.|...||.|.| ...| . |. |.|. |..| || |. | .| . ..||. |.||..|||||. .||||.|.|.||... . |.
lyafsykakkselkdkkdslkiedlekeykrlglssska.....wriskvNenYelcesYPaklivPksisdeelkkvakfrskkRlPvlsyrhkengav
LARSSQPMVGITRQKSVVDEKLV-DSI--RMACPSGKSLFLLDARPKANAIANVAKGMGYE--LNY-NCDIEFLGIANIHSMRDSINKLEQFC---QSNN
|.|||||.||.. ..| ||||. ..| . . . |.|. .|||.|.||.|| ||| |.| || .... ||||.|||..|.|..|| . | ....
lvRssqplvgllnkrskedeklleaaisaekskkekkkllivDarkklnalankakgggveseenysqaelvflgienihvvreslkklreackeanees
DENWLSGLNETRWLDHIRTLLLGVARAVSLI-NKGHPVLLHCSDGWDRTSQLSSLTMIIQDPYFRTIEGFQVLIEKEWLSFGHCFMNRVRHGDRNWYSDS
...|| |....|| ||..|| ..| |.|. .....||.|||||||||.|..|| ... |||.|||||||||.||||||||| | .||.| .| |..
eskflsslesskWLkhisslLkasalvvklveseessVlvhcsdGwDrtaqvvslaqllldpyyRtieGfqvLvekeWlsfGhkFaeRvghlkenkkssk
QRSPVFLQFIDCVYQLMNQYHDYFQFNENYLITILDALYSCQFGTFLCNSEKERQ
..|||||||.||||||..|. . |.|||..||.... ||||||||||.||||||.
esspvFlqFlDcvyqllrqfptaFeFneefLiklvehlyscqfgtFLlnsekere
|
|||||||||
Myotub-related | Myotubularin-like phosphatase domain | 527-866 | 9.3e-118 | 386.0 | In-house | 2-351 (353) | alignment | ||
Range on Protein: 527-866
Range on HMM: 2-351/353.0
LFAFKYSPNKSQLQD---GWRILNDFGEWLRQGILSETAgynmkWRYSEKNIEY-INPTYPKWLVVPHNISDEEVGICMNFRSKGRIPALSWIS-RDGVP
|.||.|...||.|.| ...| . |. |.|. |..| || |. | .| . ..||. |.||..|||||. .||||.|.|.||... . |.
lyafsykakkselkdkkdslkiedlekeykrlglssska.....wriskvNenYelcesYPaklivPksisdeelkkvakfrskkRlPvlsyrhkengav
LARSSQPMVGITRQKSVVDEKLV-DSI--RMACPSGKSLFLLDARPKANAIANVAKGMGYE--LNY-NCDIEFLGIANIHSMRDSINKLEQFC---QSNN
|.|||||.||.. ..| ||||. ..| . . . |.|. .|||.|.||.|| ||| |.| || .... ||||.|||..|.|..|| . | ....
lvRssqplvgllnkrskedeklleaaisaekskkekkkllivDarkklnalankakgggveseenysqaelvflgienihvvreslkklreackeanees
DENWLSGLNETRWLDHIRTLLLGVARAVSLI-NKGHPVLLHCSDGWDRTSQLSSLTMIIQDPYFRTIEGFQVLIEKEWLSFGHCFMNRVRHGDRNWYSDS
...|| |....|| ||..|| ..| |.|. .....||.|||||||||.|..|| ... |||.|||||||||.||||||||| | .||.| .| |..
eskflsslesskWLkhisslLkasalvvklveseessVlvhcsdGwDrtaqvvslaqllldpyyRtieGfqvLvekeWlsfGhkFaeRvghlkenkkssk
QRSPVFLQFIDCVYQLMNQYHDYFQFNENYLITILDALYSCQFGTFLCNSEKERQ
..|||||||.||||||..|. . |.|||..||.... ||||||||||.||||||.
esspvFlqFlDcvyqllrqfptaFeFneefLiklvehlyscqfgtFLlnsekere
|
|||||||||
subfamily_MTMR6_pd | Subfamily MTMR6 | 527-923 | 7.9e-112 | 366.4 | In-house | 1-395 (397) | alignment | ||
Range on Protein: 527-923
Range on HMM: 1-395/397.0
LFAFKYSPNKSQ--LQDGWRILNDFGEWLRQGILsetagyNMKWRYSEKNIEY-INPTYPKWLVVPHNISDEEVGICMNFRSKGRIPALSWIS-RDGVPL
|.||.|.|.|.. ..||. |. |. |.|. | || .. | .| . |||. |.||.... | . ||||||.| ||.. .. .
lyafsykpkkdkeekvsGwklldlkaeytrmgvp......nekwtltdlnkdyelcdtyprelyvPksatkevlvgsskfrskgrlPvlsylhkeneaai
ARSSQPMVGITRqKSVVDEKLVDSIRMACPSGKSLFLLDARPKANAIANVAKGMGYEL--NY-NCDIEFLGIANIHSMRDSINKLEQFC--QSNNDENWL
|.|||. |... ... ||||.. || | |. ..|...|.||| ||.|| |.| ||| || |. ..|.|| ||| ||.|..|| . . .|.. ...|
crcsqplsgfsa.rcledeklleairkanpnsellyvvdtrpklnalankaagkGyenednysnikfqfvgienihvmreslqkllevvelksksvsefl
SGLNETRWLDHIRTLLL-GVARAVSLINKGHPVLLHCSDGWDRTSQLSSLTMIIQDPYFRTIEGFQVLIEKEWLSFGHCFMNRVRHGDRnwySDSQRSPV
|||... || ||...| .. | .. ..|. ||.|||||||||.| ||. .. |||.|||.||.|||||||||||| | .|. . | . . ||.
sglessgwlkhikavldasifiakavaeegasvlvhcsdGwdrtaqvcslasllldpyyrtikGflvliekewlsfGhkfsercGllde...dskevsPi
FLQFIDCVYQLMNQYHDYFQFNENYLITILDALYSCQFGTFLCNSEKERQT--IKKDTVSLWSYINSNpLTPYLNPFYISYEHEtsrAFHLPEWRSEHIT
|.||..||.||..|. |.|||..|... | .|||||||||.|.||.|. .|. | |||.|. .. . ||||.| . ... . |. .. ...
ftqflecvwqlleqfpkafefnerfllelhdhvyscqfGtflgncekdrrdlklkertkslwayller.kddylnplykaetek...evlkpdtapaalk
LWKGYYLRY
||.. | |.
lwralynrf
|
|||||||||
subfamily_Dicty-MTMR1-like_pd | Subfamily Dicty-MTMR1-like | 528-924 | 9.1e-175 | 573.6 | In-house | 1-403 (404) | alignment | ||
Range on Protein: 528-924
Range on HMM: 1-403/404.0
FAFKYSPNKSQLQDGWRILNDFGEWLRQGILSETagynmKWRYSEKNIEY-INPTYPKWLVVPHNISDEEVGICMNFRSKGRIPALSWISR-DGVPLARS
|||.||..||.|.|||.|... |. |.|| ||. .||.|. |..| ...||||.||||..|||||. ...||||||||.|||..| ... ..||
fafsysekksvledgwliydaeeEykRlgikses.....eWriskinsdyelcetYPkllvvPesisDeelkkvasfRskgRiPvlswrhrsknstitRs
SQPMVGITRQKSVVDEKLVDSIRMACPSGKSLFLLDARPKANAIANVAKGMGYEL---NYNCDIEFLGIANIHSMRDSINKLEQFCQSNNDE--NWLSGL
|||.||.|...| ||||..|||.|......|..|||||||||.|| |||.||| ..||.||||.|.|||..|.|..||.....|.... |||| |
sqplvGltksrseedEklinsirkaktqletlyildarpkanavansakgagyedisryenceieflnienihelreslkklkkavnsiiekeknwlsel
NETRWLDHIRTLLLGVARAVSLIN-KGHPVLLHCSDGWDRTSQLSSLTMIIQDPYFRTIEGFQVLIEKEWLSFGHCFMNRVRHgdRNWYSDSQRSPVFLQ
...||||||..|| |..|.|.||. ....||.|||||||||||||||.....|||.||||||.||||||||||||.|..|... ....|...|||.|||
essrWldhiklllegskriveliekekssvlvhcsdgwDrtsqlsslsqllldpyyrtiegFivliekewlsfGhkfaqRigq..ttekssdersPiflq
FIDCVYQLMNQYHDYFQFNENYLITILDALYSCQFGTFLCNSEKERQ--TIKKDTVSLWSYINSNPlTPYLNPFYISYEHETSRAFHLPEWRSEH----I
||||||||..|....|.|||..||.||||||||.|||||..|||||| ...|.|||||.....| ..||||.||....|...... |..|.. |
FidcvyqltkqfptsFeFnekflikildalyscrfgtFLydsekeRqqnnlaketvslWalleank.seylnplyilekkeqkenitssessssadikli
TLWKGYYLRYW
.||. ||||..
klWseyylrwr
|
|||||||||
subfamily_MTMR9_pd | Subfamily MTMR9 | 530-923 | 8.3e-85 | 277.2 | In-house | 2-392 (393) | alignment | ||
Range on Protein: 530-923
Range on HMM: 2-392/393.0
FKYSPNKSQLQDGWRILNDFGEWLRQGIlsetagYNMKWRYSEKNIEY-INPTYPKWLVVPHNISDEEVGICMNFRSKGRIPALSWIS-RDGVPLARSSQ
| | . ..|.||. . |. .. .|| |. | .. . ..||. ..||..|.|||... .||..||.| ||.. ... .| ||||
ffyrsvatiledgysafdrenefaklis......asdewRissvNknfkvcasypesvivPkaiddeelkasaafreggrfPvLsylhketkavllrssq
PMVGITRQKSVVDEKLVDSIRMACpsgKSLFLLDARPKANAIANVAKGMGYELN--Y-NCDIEFLGIANIHSMRDSINKLEQFCQS--NNDENWLSGLNE
|..| . .. ||||.... . | . .| | | | .. .|| | | . | . . .....|. ||. || . |. . ...|| |..
plcgssgkrckedekllnlvlkkl...kkGlivdtrsksaaenarskgggietevkysqwkkasrslesvasiqdslaklleacsdaglstdkflsrlek
TRWLDHIRTLLLGVARAVSLINK-GHPVLLHCSDGWDRTSQLSSLTMIIQDPYFRTIEGFQVLIEKEWLSFGHCFMNRVRHGDRNWYSDSQRSPVFLQFI
. ||.... || .. .. .... | ||..| ..| | | |..||...| ||..||..||. |||.||. || | .|... .. .. ...|||| |.
sgwlsqvadlleaalvvaqcldeegapvvvhgeeGlDatlqvtsLaqlildpdaRtvrgfealiereWiqaGHPFasRaskvaaketkkklsgpvfllFL
DCVYQLMNQYHDYFQFNENYLITILDALYSCQFGTFLCNSEKER--QTIKKDTVSLWSYINSNP-LTPYLNPFYISyehetSRAFHLPEWRSEHITLWKG
|||||...|. | |||..||.. ||.|||||||..|.|| . .||.|||||||.|.. | .|||.| . | . ..||..
DcvyqilsqfpasFEFneelLillfehsyssqfgtflcdneaerkelklkkktvslwsyvnrpeklkqflnplyea.....naeviwpsvapqslelWse
YYLRY
|||.
lylrw
|
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subfamily_Ank-MTMR1_pd | Subfamily Ank-MTMR1 | 536-923 | 3.4e-94 | 307.9 | In-house | 9-404 (405) | alignment | ||
Range on Protein: 536-923
Range on HMM: 9-404/405.0
KSQLQDGWRILNDFGEWLRQGILSETA-GYNMKWRYSEKNIEY-INPTYPKWLVVPHNISDEEVGICMNFRSKGRIPALSWISRD-GVPLARSSQPMVGI
... |||.. |. |.|| | . |. |.... | || . .|. ||| . | .. . ||||||||.||| . ..| |||.|||
stssidgwevynqkkeylrfniyideenssncywkvtsinkeykmcssyssslvvlskaldkdlekifsfrskgripslswkdpssnasisrcsqplvgi
TRQKSVVDEKLVDSIRMACPSgKSLFLLDARPKANAIANVAKGMGYEL--NY-NCDIEFLGIANIHSMRDSINKLEQFCQSN---------NDENWLSGL
| . || . |. ...|| |.|.|.||||| ||||| |.| |.| || || . |. | ||| .| |..|| .| | . .
erarcpedelycsslalsaps.ktlylidarpklnaiantangagfenihnypncklvfmnipnihvirksleklvlamkssardkdhtestdmrfwgyi
NETRWLDHIRTLLLGVARAVSLINKGHPVLLHCSDGWDRTSQLSSLTMIIQDPYFRTIEGFQVLIEKEWLSFGHCFMNRVRHGDRNwysDSQRSPVFLQF
.|| |. ||...| . . || || .|.||||||||| |..||| |. |||.||| ||||||||||||||| | |. | | . .|||.| ||
eetgwishiksileaatfsaelilkgnsilvhcsdgwdrtpqitsltqilldpyyrtivgfqvliekewlsfghkfslrlghlpgn...eeerspifqqf
IDCVYQLMNQYHDYFQFNENYLITILDALYSCQFGTFLCNSEKER--QTIKKDTVSLWSYINSNpLTPYLNPFYISYEHETSRafhlPEWRSEHITLWKG
.||..||..|. |.| . |. | | ..||..|||| | ||.| . .| |.|.|| .| | . .|||.| . .. . | | . |||
ldccfqllsqfpllfeftpslllfisdnihsckygtflnncekdrvqdqvktktisiwsevnln.vnkflnpyynpqdiqsik....pklysrclelwka
YYLRY
|.|.
cymrv
|
|||||||||
subfamily_MTMR1_pd | Subfamily MTMR1 | 540-923 | 2.3e-132 | 433.9 | In-house | 4-386 (389) | alignment | ||
Range on Protein: 540-923
Range on HMM: 4-386/389.0
QDGWRILNDFGEWLRQGILSETagynmKWRYSEKNIEY-INPTYPKWLVVPHNISDEEVGICMNFRSKGRIPALSWISRD-GVPLARSSQPMVGITRQKS
.|||.. . | |.|.|.| .|| .. | .| . .|||. ||||...|||.. .||||||.| |||... . ..|.|||.||.. ..|
edGWkvydpeaelerlgllnek.....lWritklnkkyelcdtYpavlvvpkvvsdedlkkvaafrskgRlPvlswlnkenqavilrasqplvGlsgkrs
VVDEKLVDSIRMACPSGKSLFLLDARPKANAIANVAKGMGYE---LNYNCDIEFLGIANIHSMRDSINKLEQFCQSN-NDENWLSGLNETRWLDHIRTLL
|||... |. | . . |..||||...||.|| ||| ||| .|... || |.|||..|.|..||.. ...| .|..||| |..|.||.||...|
kedekylqaileanaqsekllildarssvnavankakgkgyeseeaYknaelifldihnihvvReslkklkelvlpnvddkkwlsalestkWlehiklil
LGVARAVSLINKG-HPVLLHCSDGWDRTSQLSSLTMIIQDPYFRTIEGFQVLIEKEWLSFGHCFMNRVRHGDRNwYSDSQRSPVFLQFIDCVYQLMNQYH
| . |. ... . ||.|||||||||.|| ||.|.. |.|.||||||.|||||||||||| | .|. |||.| .||..||||||||||||.||..|.
agavkivekvetektsvlvhcsdGWDRtaqltsLamlllDsyyRtieGfevliekeWlsfGHkfkeRlghgdkn.ssdaersPvFlqfiDcvwqltrqfp
DYFQFNENYLITILDALYSCQFGTFLCNSEKERQ--TIKKDTVSLWSYINSNpLTPYLNPFYISYEHetsRAFHLPEWRSEHITLWKGYYLRY
|.|||..|||.|| |||| |||||.||||||. ..|. |||||||.||. . . ||.| .. . . |.. ... ||| ||||.
tAFefneefLitlldhlysclfGtflfnsekervkekvkektvslwsyvnss.keeftnplyaeele...kkvlypkaslrrlelWkeyylrw
|
|||||||||
0040695 | (Phosphotyrosine protein) phosphatases II | 540-924 | 4.1e-119 | 391.6 | In-house | 5-386 (388) | alignment | ||
Range on Protein: 540-924
Range on HMM: 5-386/388.0
QDGWRILNDFGEWLRQGILSEtagynmKWRYSEKNIEY-INPTYPKWLVVPHNISDEEVGICMNFRSKGRIPALSWISR-DGVPLARSSQPMVGITRQKS
..|| ... . |. |.|. . ||.| | .| . |.|| .|||| ||||.. ...||||||||.||.. . .| | |||||.||.. ..|
eegwslydilrelkrlglgld......lwrisivNenyelcpsYPallvVPksisdellkrvarfrskgriPvlsyrhpnngavllRssqplvglllsrs
VVDEKLVDSIRMACPSGKSLFLLDARPKANAIANVAKGMGYEL---NYNCDIEFLGIANIHSMRDSINKLEQFCQSN-NDENWLSGLNETRWLDHIRTLL
. ||||...|. ..|. . |...|.|||.||.||.|.|.|.| .|... ||.| ||| .|.| .|| ..| .. .. |.|| |.|..|||.|...|
ledeklleailkllpnlskllivdlrpklnalanralgggvenedaypnaeliflnipnihvvreslqklldaclnvpdslnllslleesgwldliklil
LGVARAVSLINKGHP-VLLHCSDGWDRTSQLSSLTMIIQDPYFRTIEGFQVLIEKEWLSFGHCFMNRVRHgDRNWYSDSQRSPVFLQFIDCVYQLMNQYH
.. .|.|...|. ||.|||||||||||||||.... |||.||.||||||||||||||||.|..|. | ........|||||.|.|||.||..|.
elavlivklldlgnssvlvhcsdgwdrtsqlssLaqllldPyYRTleGFqvLiekeWlsfghkfadRlgh.leseidskefsPvFllFLdcvwqLlrqfP
DYFQFNENYLITILDALYSCQFGTFLCNSEKER--QTIKKDTVSLWSYINSNPLTpYLNPFYISYEHEtsraFHLPEWRSEHITLWKGYYLRYW
|.|||..|....| ||||.|||||.|||||| .. . |.|||||..|. .|||.| ....| ..|| .. ...|| .||||..
taFeFnerlLlfLadhlyscrfgtFlfnsekerlelsvsertlslwsyllsrkse.flnplYdpssle....vllpslsvldlllWleyylrwl
|
|||||||||
subfamily_MTMR5_pd | Subfamily MTMR5 | 551-634 | 1.8e-09 | 28.9 | In-house | 13-103 (483) | alignment | ||
Range on Protein: 551-634
Range on HMM: 13-103/483.0
EWLRQGILSE-TAGYNMKWRYSEKNIEY-INPTYPKWLVVPHNISDEEVGICMNFRSKGRIPALSWISR-DGVPLARSSQP----MVGITR
.. | |. .. .| . |.| || | .| . .|| .|||...||... . ..|.|. | .. . | ||... .||. .
dykRlGlgalngaskrgkfrisevNkkytvcrsYPalivvPsevsddsiarvakcfrqnRlPvvtWrhernkalLiRsggfeskgvvgllk
|
|||||||||
subfamily_MTMR3_pd | Subfamily MTMR3 | 562-653 | 1.7e-18 | 59.6 | In-house | 36-131 (442) | alignment | ||
Range on Protein: 562-653
Range on HMM: 36-131/442.0
AGYN--MKWRYSEKNIEY-INPTYPKWLVVPHNISDEEVGICMNFRSKGRIPALSWIS-RDGVPLARSSQPMVGITRQKSVVDEKLVDSIRMACPS
|.. .|| |. | .. . ..||| |.||. |.|... . .||| .|.||. | ..| |||.||| ||. .. ||||...| || .
lGfdlkeawrisdvnsdfklCssyPkklivPksitdddlkkvasfrslkrlPavvwrhkkngavlarcsqPevgwlgWrnaedekllkaiakacal
|
|||||||||
subfamily_MTMR10_pd | Subfamily MTMR10 | 565-890 | 7e-51 | 165.1 | In-house | 23-311 (380) | alignment | ||
Range on Protein: 565-890
Range on HMM: 23-311/380.0
NMKWRYSEKN-IEYINPTYPKWLVVPHNISDEEVGICMNFRSKGRIPALSWISRDGVPLARSSQPMVgiTRQKSVVDEKLVDSIRMACPSGKSLFLLDAR
..... . || .. .|.|. .|||. .||..| .. ..| | ..| .| | | |. . .. .|. . .| ... . |.|
sdaivvllknelfaaaqtlPqyfvvpnslsdsdverlsrhykesRfplwvwshakgaallrlsalqe..aesadkekeekmlelvrkchpandvklvdls
PKANAIANVAKGmgyelnYNcdieflgiaNIHSMRdSINKLEQFCQsnNDENWLSGLNETRWLDHIRTLLLGVARAVSLI-NKGHPVLLHCSDGWDRTSQ
... |..| |. |. ..... |. |.|.. |..||| |..||||. .|..| . || .. .|...|.| |.| |
delpsiqdvqka......yl.........klreLc.vidtseefvt..lddkwlssLektrWLayvrlclstasdavktvvekkrsvilqesegrDlscv
LSSLTMIIQDPYFRTIEGFQVLIEKEWLSFGHCFMNRVRHGDRNWYSDSqrsPVFLQFIDCVYQLMNQYHDYFQFNENYLITILDALYSCQFGTFLCNSE
..||. .. ||..|||.||| ||.||| . ||.|..|. |.... |.| |||| | |||.||..|. . |.|.| .||...| .|. |.|||.|||
vaSLaqlmldphyrtisGfqsliqkewvaaghpfldrlghikpsekses...pvfllFldcvdqlleqfpseFeFtetfLialwdsshsgifltflfnse
KERQTIKKDTVslwsyinsnpltpylnP
..|.. ... |
eqrlkavvsss................p
|
|||||||||
subfamily_MTMR3_pd | Subfamily MTMR3 | 655-921 | 1.5e-86 | 283.9 | In-house | 173-440 (442) | alignment | ||
Range on Protein: 655-921
Range on HMM: 173-440/442.0
KSLFLLDARPKANAIANVAKGMGYELN---YNCDIEFLGIANIHSMRDSINKLEQFCQSNNDE-NWLSGLNETRWLDHIRTLLLGVARAVSLINK-GHPV
|.|...||| . |.|| ||| |.||. ||...|||.||||..| | |.| ..... .|| |||| |..|.|| .. .|| .. |. ..| |.||
kkllivdarsytaafanrakgGGceleeyypncevvflglanihavrksfnslrallsqspdesnwlsalektkWlqnlsvllkaavkvveavdkegrpv
LLHCSDGWDRTSQLSSLTMIIQDPYFRTIEGFQVLIEKEWLSFGHCFMNRVRHGDrNWYSDSQRSPVFLQFIDCVYQLMNQYHDYFQFNENYLITILDAL
|.|||||||||.|. .|. .. |||.||.|||.||.|.|||.||| |..|. ||. |. .|.|||||..|.|.|| .|. |.||| .|. ..
lvhCsdGWdrttqivalakllldpyyrtleGfkvlvereWldfGhkfadrcghge.nvddanercPvflqwldavhqlqrqfPtsfefneaflvklvqht
YSCQFGTFLCNSEKERQ--TIKKDTVSLWSYINSNPlTPYLNPFYisyEHEtSRAFHLPEWRSEHITLWKGYYL
||| |||||.||||||. ..|. |.|.||..... . | | | ... . | || . ...||. ||
ysclfGtflansekereeekvkertlsvWsllrake.keyrnlly...kek.teavllpavsvrelklwsevyl
|
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subfamily_MTMR5_pd | Subfamily MTMR5 | 673-917 | 1.4e-51 | 167.8 | In-house | 217-476 (483) | alignment | ||
Range on Protein: 673-917
Range on HMM: 217-476/483.0
AKGMGYELNYNCDIEFLGIANIHSMRDSINKLEQFCQSNND----E--NWLSGLNETRWLDHIRTLLLGVARAVSLIN-KGHPVLLHCSDGWDRTSQLSS
.|.. | . .... . . .| .. |..|| . | .... | .|. ... || |..|| . .| |.. .| ||. |||| |.|.||
lknvksevdskaefipvelveirqvkasfkkllraClpstaveeaesqsFlksvedseWlqqissllqlsgavvdlldlqgssvlvslEdGwdvtaqvss
LTMIIQDPYFRTIEGFQVLIEKEWLSFGHCFMNRVRHGDRNwySDSQRSPVFLQFIDCVYQLMNQYHDYFQFNENYLITILDALYSCQFGTFLCNSEKER
|. ...|||.||.|||.||.|||||.||| | .| . . . | .||||||.|||.|...|. | ||. || .. |..| ||| .||.||
laqllldpyYRtleGFkvLveKEWLafGHrFtkrsnqtlsa..qssgfaPvFlqFLDcvhqvsrqfPlafefndfylkflayhsvsnrfrtfllDseyer
QTI------------KKDTVSLWSYINS-NPLTPYLnpFYISYEHETSRAFHlPEWRSEHITLWK
|| ..|.| ||. .. .| . |. . | ... |. . ....|.
lesgllyeekaekrakkagksvwdyidrqhkrspif..ynflyspdesevlr.PssnvsslkvWd
|
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subfamily_pats1_pd | Subfamily pats1 | 683-806 | 3.8e-28 | 90.3 | In-house | 335-463 (691) | alignment | ||
Range on Protein: 683-806
Range on HMM: 335-463/691.0
NCDIEFLGIANIHSMRDSINKLEQ--FCQSNNDENWlSGLNETRWLDHIRTLLLGVARAVSLINKGHPVLLH-CSDGWDRTSQL---SSLTMIIQDPYFR
..|.|| . . ... ..| | ..|..| . . | |.| .. || .. . |...|. |||. .|. . . .| |||.... ||..|
ssniiflslPtrekveerffdllqsilsldgsddew.keieeskwvdsvkllleaavkvsnlldeGssvllknsidsPlieldlasisslaqvlsdPfyr
TIEGFQVLIEKEWLSFGHCFMNRVRHGDRN
|..||.|||||||||.|. | .. | ...
tldGfkvliekewlsyGfPfskinyhkesd
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0051429 | (Phosphotyrosine protein) phosphatases II | 708-775 | 5.8e-08 | 28.2 | In-house | 113-179 (272) | alignment | ||
Range on Protein: 708-775
Range on HMM: 113-179/272.0
CQSNNDENWLSGLNETRWLDHIRTLLLgVARAVSLINKGHPVLLHCSDGWDRTSQLSSLTMIIQDPYF
. |... .. | |.|.|| . ....|...|.||| ||| |.||| .. | .....
llsagearevmhlhytdwpdhgvpqea.llellellldggpvlvHCsaGkdRTGtvvallllllgvsl
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PTPc_DSPc_SM00012 | 727-845 | 1.5e-10 | 36.6 | In-house | 20-100 (105) | alignment | |||
Range on Protein: 727-845
Range on HMM: 20-100/105.0
DHIRTLLLGVARAVSLINKGHPVLLHCSDGWDRTSQLSSLTMIIQDPYFRTiegfqvliekewlsfghcfmnrvrhgdrnwysdsqrspVFLQFIDCVYQ
|.| .|| | . . .....||..|||.|..|| .. | ...|. . .| .... ..| .
dsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleket......................................kevdifqivke
LMNQYHDYFQFNENYLITI
|..| . ..|..|.||. .
lrkqRpgmvqteeqylfly
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0051082 | (Phosphotyrosine protein) phosphatases II | 734-773 | 2.9e-06 | 22.5 | In-house | 78-119 (151) | alignment | ||
Range on Protein: 734-773
Range on HMM: 78-119/151.0
LGVARAVSLIN--KGHPVLLHCSDGWDRTSQLSSLTMIIQDP
|.....|.. |..||| ||| |..|| | | .....
davleflellldkkngpvlvHCsaGkgRTGtlvalylmllgv
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subfamily_pats1_pd | Subfamily pats1 | 813-892 | 1.8e-20 | 64.9 | In-house | 552-632 (691) | alignment | ||
Range on Protein: 813-892
Range on HMM: 552-632/691.0
RSPVFLQFIDCVYQLMNQYHDYFQFNENYLITILDALYSCQFGTFLCNSEKERQ--TIKKDTVSLWSYINSNPLTpYLNPFY
||.|.||.| |.|| .. .|.||| .|..... .| .||.||.. |.. . | . |.||.|| | . ..| .|
fsPifvqfldlvwqlqkefPfhfefneslllllvkesfssrfGnflyseakrdserkvlkrsksiwsfinqnksr.finlly
|