Gene roco9 in Dictyostelium discoideum

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family Myotubularin
Subfamily pats1
Protein sequence
ID Type Fasta BLAST phosphatome Note
DdisP033_AA protein Get Run
DdisP033_AA_803-1492 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_pats1_pd Subfamily pats1 385-468 1.5e-06 18.9 In-house 211-293 (691) alignment 
Range on Protein: 385-468
Range on HMM: 211-293/691.0
LFKQQQQQQQQrESTEVLTLSLSSSTSTLEPEPQPLPLSTSTQRLPQQSSDDNSNNDNNNKNDNDNDNDNDNNNDNNNINNDNG
|| ....| |.  |.  |. || ||.  |. | | .      ..| ..| ..| ||.|||.|.|.|.|.|.|||.||| ||.|.
lfvnkeeqlqs.ssssslstslnsssnnlnkefqqihqqmqqnqlnsssnnnnnnnnnnnsnnnnnnnnnnnnnnnnnnnnnnn
0040695 (Phosphotyrosine protein) phosphatases II 799-1489 7.8e-69 226.2 In-house 2-387 (388) alignment 
Range on Protein: 799-1489
Range on HMM: 2-387/388.0
DYTTNIWDIYSPLIEGQRLKLDLDkDWRVVEFLSR-DTSTIYPKRILIPNLIGDELLQSYVR-KTQSKIPIFSWSNQNNKSMLFRICvynQPFNnkfnsg
 .....| .|..| | .||.|.||  ||.. . .. . .. || ....|. | ||||....|   . .||..|....||...|.|..   ||..      
llleegwslydilrelkrlglgld.lwrisivNenyelcpsYPallvVPksisdellkrvarfrskgriPvlsyrhpnngavllRss...qplv......

gtlaynnnstiinnnsviitnsstigtntsgisnsnhlivgeieppspikkrqqqivdkkdtssplsslrsskgipsksskkdkqgflssstssiipiqt
                                                                                                    
....................................................................................................

tistdtvdvklynlfvnkeeqlqsstssspstslnNSSNNLNKEFQQIHQQMQQNQLnsssnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnNNNNN
                                   . ... ..|........ .                                         |....
...................................glllsrsledeklleailkllp......................................nlskl

KINKRQNEATIVFTNKVGGTSDNHINIISvyeqfkmnsSNIIFLSIPTREQVEACWFDLYQSITSFDGSMDAWKSIEESKWVDSVKLLLEGCVKVSNLLD
 | .  . . ....  .||  .|. . ..          ..|||.||  ..| .....|.. ......|.. ....|||.| | .||.||..| . .|||
livdlrpklnalanralgggvenedaypn.........aeliflnipnihvvreslqklldaclnvpdslnllslleesgwldliklilelavlivklld

EGSSVLLKPPIDsplHTLDLASISSLTMVLSDPFYRTLDGFLILIEKEWIQYGFPFNNINYHKEQNNlnnnngnkensssssssssststtpsitkkssg
 |.|..| . .|   ..   . .|||...| ||.||||.||..||||||...|..| .   | |...                                 
lgnssvlvhcsd...gwdrtsqlssLaqllldPyYRTleGFqvLiekeWlsfghkfadRlghlesei.................................

siskgssgiaslindldkydsnfvlpdtihtesqkkktylfqdqyessilVNRSFSPIFVQFLDAVWQLQRQFPFHFEFNESLLLLLVKESFSGRFGNFL
                                                   . .|||.|..|||.||||.||||..||||| |||.|. ...|.|||.||
..................................................dskefsPvFllFLdcvwqLlrqfPtaFeFnerlLlfLadhlyscrfgtFl

YSEALRDSERKFLKRSPSIWTFINQNKSTFINLLYKHSAnssssssstnklpspisprqsfifkqedfNEMIKPSCDNDQIILWSSFFTEFIN
.    .  | .. .|  |.|......|| |.|.||..|                              .|...||... ...||.... ....
fnsekerlelsvsertlslwsyllsrkseflnplYdpss.............................levllpslsvldlllWleyylrwlp
subfamily_Dicty-MTMR1-like_pd Subfamily Dicty-MTMR1-like 799-881 1.3e-10 33.0 In-house 10-94 (404) alignment 
Range on Protein: 799-881
Range on HMM: 10-94/404.0
DYTTNIWDIYSPLIEGQRLKLDLDKDWRVVEFLSR-DTSTIYPKRILIPNLIGDELLQSYV-RKTQSKIPIFSWSNQNNKSMLFR
 . .. | ||..  | .||..  . .||. .  |  . .  ||| . .|. | || |.. .  ... .||. || .....| . |
svledgwliydaeeEykRlgikseseWriskinsdyelcetYPkllvvPesisDeelkkvasfRskgRiPvlswrhrsknstitR
subfamily_pats1_pd Subfamily pats1 800-1490 0.0 1417.2 In-house 1-691 (691) alignment 
Range on Protein: 800-1490
Range on HMM: 1-691/691.0
YTTNIWDIYSPLIEGQRLKLDLDKDWRVVEFLSRDTSTIYPKRILIPNLIGDELLQSYVRKTQSKIPIFSWSNQNNKSMLFRICVYNQPFNNKFNSGGTL
|||.|.||||.||||||||||||||||||||||||.|.|||||||.|.|..||||.|||||..||||..|||||||||.|||||||||||||||||||||
ytteifdiyslliegqrlkldldkdwrvveflsrdlseiyPkrilvPklvsdellvsyvrkrsskiPvlswsnqnnksslfricvynqpfnnkfnsggtl

AYNNNSTIINNNSVIITNSSTIGTNTSGISNSNHLIVGEIEPPSPIKKRQQQIVDKKDTSSPLSSLRSSKGIPSKSSKKDKQGFLSSSTSSIIPIQTTIS
|||||||||||||||||.||.|..||||||.||.|.||||||.|||||||||||||||||||||||||||||||||||||||||||||||||||||||||
aynnnstiinnnsviitrsssiedntsGisssnyllvgeiePnsPikkrqqqivdkkdtssplsslrsskgipsksskkdkqgflssstssiipiqttis

TDTVDVKLYNLFVNKEEQLQSSTSSSPSTSLNNSSNNLNKEFQQIHQQMQQNQLNSSSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNKIN
||||||||||||||||||||||.|||.|||||.||||||||||||||||||||||||||||||||||||.||||||||||||||||||||||||.|.|||
tdtvdvklynlfvnkeeqlqsssssslstslnsssnnlnkefqqihqqmqqnqlnsssnnnnnnnnnnnsnnnnnnnnnnnnnnnnnnnnnnnnsnskin

KRQNEATIVFTNKVGGTSDNHINIISVYEQFKMNSSNIIFLSIPTREQVEACWFDLYQSITSFDGSMDAWKSIEESKWVDSVKLLLEGCVKVSNLLDEGS
||.||||||.|.||.|||||..|..||||.|||.||||||||.||||.||...|||.|||.|.|||.|.||.|||||||||||||||..|||||||||||
krdneativltkkvsgtsdnslnllsvyesfkmissniiflslPtrekveerffdllqsilsldgsddewkeieeskwvdsvkllleaavkvsnlldeGs

SVLLKPPIDSPLHTLDLASISSLTMVLSDPFYRTLDGFLILIEKEWIQYGFPFNNINYHKEQNNLNNNNGNKENSSSSSSSSSSTSTTPSITKKSSGSIS
|||||..|||||..|||||||||..|||||||||||||..||||||..|||||..||||||...||||||||||||||||||||||||||||||||||||
svllknsidsPlieldlasisslaqvlsdPfyrtldGfkvliekewlsyGfPfskinyhkesddlnnnngnkensssssssssststtpsitkkssgsis

KGSSGIASLINDLDKYDSNFVLPDTIHTESQKKKTYLFQDQYESSILVNRSFSPIFVQFLDAVWQLQRQFPFHFEFNESLLLLLVKESFSGRFGNFLYSE
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||.|||||..|||||||||||||||||||||.|||||||||
kgssgiaslindldkydsnfvlpdtihtesqkkktylfqdqyessilvnrsfsPifvqfldlvwqlqkefPfhfefneslllllvkesfssrfGnflyse

ALRDSERKFLKRSPSIWTFINQNKSTFINLLYKHSANSSSSSSSTNKLPSPISPRQSFIFKQEDFNEMIKPSCDNDQIILWSSFFTEFINS
|.||||||.||||.|||.|||||||.||||||||||.|||||||..||.||||.|.||..|.||||||||||||||||||||.||||||||
akrdserkvlkrsksiwsfinqnksrfinllykhsassssssssssklsspissrvsflkkledfnemikpscdndqiilwsefftefins
subfamily_MTMR1_pd Subfamily MTMR1 801-887 2.7e-09 28.8 In-house 3-91 (389) alignment 
Range on Protein: 801-887
Range on HMM: 3-91/389.0
TTNIWDIYSPLIEGQRLKLDLDKDWRVVEFLSR-DTSTIYPKRILIPNLIGDELLQSYVR-KTQSKIPIFSWSNQNNKSMLFRICVYNQ
... |..|.|  | .|| |  .| ||...  .. . .  ||. . .|. . || |.   . . ....|. || |..|.... | .  ..
kedGWkvydpeaelerlgllneklWritklnkkyelcdtYpavlvvpkvvsdedlkkvaafrskgRlPvlswlnkenqavilrasqplv
Myotub-related Myotubularin-like phosphatase domain 803-1398 3.7e-48 157.0 Pfam-A 19-345 (353) alignment
Myotub-related Myotubularin-like phosphatase domain 803-1398 3.7e-48 157.0 In-house 19-345 (353) alignment
subfamily_Dicty-MTMR1-like_pd Subfamily Dicty-MTMR1-like 1015-1486 1.2e-38 125.3 In-house 121-401 (404) alignment 
Range on Protein: 1015-1486
Range on HMM: 121-401/404.0
EEQLQsstssspstslnnssnnlnkefqQIHQQMQQNQLNSSSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNKINKRQNEativftnkvg
..||.                       ..  . .. ..|...|... ..... ....| ...  | .| .. ... .. .. .|  ...          
ktqle.......................tlyildarpkanavansakgagyedisryenceieflnienihelreslkklkkavnsiiek..........

gtsdnhiniisvyeqfkmnssniiflsiptreqveacwfdlyqsitsfdgsMDAW-KSIEESKWVDSVKLLLEGCVKVSNLLD-EGSSVLLKpPIDSPLH
                                                    . | . .|.|.|.| .||||||  ....|.. |.||||..  .|    
...................................................eknwlselessrWldhiklllegskriveliekekssvlvh.csdgwDr

TldlASISSLTMVLSDPFYRTLDGFLILIEKEWIQYGFPFNNINYHkeqnnlnnnngnkensssssssssststtpsitkkssgsiskgssgiaslindl
|   . .|||...| ||.|||. || .||||||...|  |.. . .                                                      
t...sqlsslsqllldpyyrtiegFivliekewlsfGhkfaqRigq......................................................

dkydsnfvlpdtihtesqkkktylfqdqyeSSILVNRSFSPIFVQFLDAVWQLQRQFPFHFEFNESLLLLLVKESFSGRFGNFLYSEALRDSERKFLKRS
                              ..   .  .||||.||.|.|.|| .||| .|||||..|. ..... |.|||.|||      ....  |  
..............................ttekssdersPiflqFidcvyqltkqfptsFeFnekflikildalyscrfgtFLydsekeRqqnnlaket

PSIWTFINQNKSTFINLLYKHSANSSSSSSSTNKLP--SpisprqsfifkqedfnemikpscDNDQIILWSSFFTE
.|.|. ...|||...| || .. . .... ....    .                       |  .| |||... .
vslWalleankseylnplyilekkeqkenitssessssa.......................dikliklWseyylr
subfamily_MTMR5_pd Subfamily MTMR5 1019-1259 1.2e-23 75.7 In-house 129-354 (483) alignment 
Range on Protein: 1019-1259
Range on HMM: 129-354/483.0
QSSTSSSPSTSLNNSSnnlnkefQQIHQQMqqNQLNSSSNNNNNNNNNN-NNNNNNNNNNNNNNNNNNNNNNNNNNNNNKINKRQNEATIVFTNKVGgTS
. . .. ...|  ...       .... ..  ..|.|||....... .. .|. . ..... ..... .  ..|| ...| .. .. |  |. .|     
kavvnevsklsalaln.......sslevsl..svlasssssdkraalsteknaldisksdkasqggkgatlkennakeskklrarkaaLYvlgeksq.lk

DNHINIISVYEQFKMNSSNIIFLSIPTREQVEACWFDLyqsiTSFDGSMD-AWKSIEESKWVDSVKLLLEGCVKVSNLLD-EGSSVLLKppIDSPLH-Tl
. .... |  |   ... .|  .    .  . ||  .     .. . ..    ||.|.| |.  .. ||.  . |..||| .|||||.   ..     | 
nvksevdskaefipvelveirqvkasfkkllraClpst....aveeaesqsFlksvedseWlqqissllqlsgavvdlldlqgssvlvs..lEdGwdvt.

dlASISSLTMVLSDPFYRTLDGFLILIEKEWIQYGFPFNNINYHK
  | .|||. .|.||.||||.|| .|.||||. .|  |..   ..
..aqvsslaqllldpyYRtleGFkvLveKEWLafGHrFtkrsnqt
subfamily_MTMR3_pd Subfamily MTMR3 1053-1263 1.6e-17 56.4 In-house 134-330 (442) alignment 
Range on Protein: 1053-1263
Range on HMM: 134-330/442.0
LNSSSNNNNNNNNNnNNNNNNNNNNNNNNNNNNNNNNNNNNNNNKINKRQNEATIVFTNKVGGTSdnhinIISVYeqfkmNSSNIIFLSIPTREQVEACW
 . ....   |... .... ... ... . .....  .....   .. |   |..    | ||           |     ......||...    |   .
gekakgeklsngka.kkkdvsdaldaeadaseeeslaeekkkllivdarsytaafanrakgGGce.....leeyy.....pncevvflglanihavrksf

FDLYQSITSFDGSMDAWKSIEESKWVDSVKLLLEGCVKVSNLLDE-GSSVLLKpPIDSPLHTldlASISSLTMVLSDPFYRTLDGFLILIEKEWIQYGFP
  | . ...   ... . ..|. ||.  .  ||. .|||.. .|. | .||.    |    |   . | .|. .| ||.||||.|| .|.|.||...|  
nslrallsqspdesnwlsalektkWlqnlsvllkaavkvveavdkegrpvlvh.CsdGWdrt...tqivalakllldpyyrtleGfkvlvereWldfGhk

FNNINYHKEQNN
|..   |.|. .
fadrcghgenvd
subfamily_MTMR1_pd Subfamily MTMR1 1102-1266 1.2e-21 69.5 In-house 114-276 (389) alignment 
Range on Protein: 1102-1266
Range on HMM: 114-276/389.0
QNEATIVFTNKVGGTSDNHINIISVYE-QFKMNSSNIIFLSIPTREQVEACWFDLYQSITSFDGSMDAWKSIEESKWVDSVKLLLEGCVKVSNLLDEGSS
| |  ......   .. .  .    || . . .  ..||| |.. . | . .  | . . .   . .  ...|..||.. .||.|.|.||. . ... ..
qsekllildarssvnavankakgkgyeseeaYknaelifldihnihvvReslkklkelvlpnvddkkwlsalestkWlehiklilagavkivekvetekt

VLLKPPIDSPLHTldlASISSLTMVLSDPFYRTLDGFLILIEKEWIQYGFPFNNINYHKEQNNLNN
  |    |    |   | . ||.|.| |..|||..|| .||||||...| .|..   | ..|. ..
svlvhcsdGWDRt...aqltsLamlllDsyyRtieGfevliekeWlsfGHkfkeRlghgdknssda
subfamily_MTMR9_pd Subfamily MTMR9 1116-1258 2.4e-16 51.8 In-house 138-273 (393) alignment 
Range on Protein: 1116-1258
Range on HMM: 138-273/393.0
TSDNHINIISVYEQFKMNSSNIiflsiPTREQVEACWFDLYQSITSFDGSMDAWK-SIEESKWVDSVKLLLEGCVKVSNLLDE-GSSVLLKPpidspLHT
. . .|.  . | |.|..| ..        ....     | ....    |.| .   .|.|.|...|. |||  ..|...||| |..|...       . 
skgggietevkysqwkkasrsl.....esvasiqdslaklleacsdaglstdkflsrleksgwlsqvadlleaalvvaqcldeegapvvvhg.....eeG

LDLA-SISSLTMVLSDPFYRTLDGFLILIEKEWIQYGFPFNNINYH
|| .  ..||.... || .||..||  |||.|||| | ||.. . .
lDatlqvtsLaqlildpdaRtvrgfealiereWiqaGHPFasRask
subfamily_Ank-MTMR1_pd Subfamily Ank-MTMR1 1165-1258 1.3e-15 49.1 In-house 200-289 (405) alignment 
Range on Protein: 1165-1258
Range on HMM: 200-289/405.0
SMDAWKSIEESKWVDSVKLLLEGCVKVSNLLDEGSSVLLKPpIDSPLHTldlASISSLTMVLSDPFYRTLDGFLILIEKEWIQYGFPFNNINYH
 |  |  |||. |.  .| .|| .   ..|.  | |.|..   |   .|     |.||| .| ||.|||. || .||||||. .|  |     |
dmrfwgyieetgwishiksileaatfsaelilkgnsilvhc.sdgwdrt...pqitsltqilldpyyrtivgfqvliekewlsfghkfslrlgh
subfamily_MTMR6_pd Subfamily MTMR6 1165-1256 3.4e-15 48.2 In-house 189-277 (397) alignment 
Range on Protein: 1165-1256
Range on HMM: 189-277/397.0
SMDAWKSIEESKWVDSVKLLLEGCVKVSNLL-DEGSSVLLKPpIDSPLHTldlASISSLTMVLSDPFYRTLDGFLILIEKEWIQYGFPFNNIN
  . ....|.|.|.  .| .|. .. ... . .|| |||.    |    |   | . ||. .| ||.|||..|||.||||||. .|  |.. .
vseflsglessgwlkhikavldasifiakavaeegasvlvhc.sdGwdrt...aqvcslasllldpyyrtikGflvliekewlsfGhkfserc
subfamily_MTMR10_pd Subfamily MTMR10 1167-1484 1.9e-25 81.5 In-house 153-374 (380) alignment 
Range on Protein: 1167-1484
Range on HMM: 153-374/380.0
DAWK-SIEESKWVDSVKLLLEGCVKVSNLL-DEGSSVLLKPPIDSPLHTLdlasISSLTMVLSDPFYRTLDGFLILIEKEWIQYGFPFNN-INYHKEQNN
| |  |.|...| ..|.|.|.  ....... ... ||.|.   .. |  .    ..||. ...||.|||..||  ||.|||.  |.|| . .. .|....
dkwlssLektrWLayvrlclstasdavktvvekkrsvilqesegrDlscv....vaSLaqlmldphyrtisGfqsliqkewvaaghpfldrlghikpsek

LNNnngnkensssssssssststtpsitkkssgsiskgssgiaslindldkydsnfvlpdtihtesqkkktylfqdqyessilvnrsfsPIFVQFLDAVW
 ..                                                                                      |.|. ||| |.
ses......................................................................................pvfllFldcvd

QLQRQFPFHFEFNESLLLLLVKESFSGRFGNFLYSEAlRDSERKFLKRSPSIWT--FINQNKSTFINLLYKHSANSSSsSSSTNKLPSPISPRQSfifkq
|| .|||. |||.|..|. |.  |.|| |..||  .. .  ...  ..|| . .  . ..|.. . .| |... .  .   | ..| .  | ..|     
qlleqfpseFeFtetfLialwdsshsgifltflfnse.eqrlkavvsssplliakselkendllkdeldyrqglyaei.iksirrlaaaksylrs.....

edfnEMIKPSCDNDQIILWSSFF
    |.|.|     .| ||.  .
....eiirPllqipdiqlWdeCY
subfamily_MTMR6_pd Subfamily MTMR6 1348-1439 3.6e-24 77.8 In-house 284-375 (397) alignment 
Range on Protein: 1348-1439
Range on HMM: 284-375/397.0
NRSFSPIFVQFLDAVWQLQRQFPFHFEFNESLLLLLVKESFSGRFGNFLYSEALRDSERKFLKRSPSIWTFINQNKSTFINLLYKHSANSSS
.. .|||| |||..||||..|||  |||||. || | .  .| .||.||        . |. .|. |.|... ..|. ..| |||...... 
skevsPiftqflecvwqlleqfpkafefnerfllelhdhvyscqfGtflgncekdrrdlklkertkslwayllerkddylnplykaetekev
subfamily_MTMR5_pd Subfamily MTMR5 1348-1434 1.4e-13 42.5 In-house 359-458 (483) alignment 
Range on Protein: 1348-1434
Range on HMM: 359-458/483.0
NRSFSPIFVQFLDAVWQLQRQFPFHFEFNESLLLLLVKESFSGRFGNFLYSEALRDSERKFlkrS-------------PSIWTFINQN---KSTFINLLY
. .|.|.|.||||.|.|..||||  ||||.  | .|   | | ||  ||.   .. .|                     |.| .|...    . | | ||
ssgfaPvFlqFLDcvhqvsrqfPlafefndfylkflayhsvsnrfrtfllDseyerlesgl...lyeekaekrakkagksvwdyidrqhkrspifynfly

KHS
. .
spd
subfamily_MTMR9_pd Subfamily MTMR9 1349-1436 1e-22 72.8 In-house 282-371 (393) alignment 
Range on Protein: 1349-1436
Range on HMM: 282-371/393.0
RSFSPIFVQFLDAVWQLQRQFPFHFEFNESLLLLLVKESFSGRFGNFLYSEALRDSERKFLKRSPSIWTFINQN--KSTFINLLYKHSAN
.  .|.|. |||.|.|. .|||  |||||.|| || ..|.| .||.||.... . .| |  |.  |.|...|..   ..|.|.||.. |.
klsgpvfllFLDcvyqilsqfpasFEFneelLillfehsyssqfgtflcdneaerkelklkkktvslwsyvnrpeklkqflnplyeanae
subfamily_MTMR1_pd Subfamily MTMR1 1351-1436 1.2e-25 82.7 In-house 278-363 (389) alignment 
Range on Protein: 1351-1436
Range on HMM: 278-363/389.0
FSPIFVQFLDAVWQLQRQFPFHFEFNESLLLLLVKESFSGRFGNFLYSEALRDSERKFLKRSPSIWTFINQNKSTFINLLYKHSAN
 ||.|.||.|.||||.||||. |||||..|. |. .. |..||.||.    .  ..|  ..  |.|...|..|..|.| ||... .
rsPvFlqfiDcvwqltrqfptAFefneefLitlldhlysclfGtflfnsekervkekvkektvslwsyvnsskeeftnplyaeele
subfamily_Ank-MTMR1_pd Subfamily Ank-MTMR1 1351-1433 5.5e-13 40.4 In-house 297-379 (405) alignment 
Range on Protein: 1351-1433
Range on HMM: 297-379/405.0
FSPIFVQFLDAVWQLQRQFPFHFEFNESLLLLLVKESFSGRFGNFLYSEALRDSERKFLKRSPSIWTFINQNKSTFINLLYKH
 |||| ||||...||  |||. |||  ||||..  .  | ..| ||        . .   .. |||. .| |   |.|  |. 
rspifqqfldccfqllsqfpllfeftpslllfisdnihsckygtflnncekdrvqdqvktktisiwsevnlnvnkflnpyynp
subfamily_MTMR3_pd Subfamily MTMR3 1352-1436 4e-21 68.3 In-house 336-420 (442) alignment 
Range on Protein: 1352-1436
Range on HMM: 336-420/442.0
SPIFVQFLDAVWQLQRQFPFHFEFNESLLLLLVKESFSGRFGNFLYSEALRDSERKFLKRSPSIWTFINQNKSTFINLLYKHSAN
.|.|.|.|||| |||||||  |||||. |. ||. ..|. || ||   .   .|.|  .|  |.|....... .. |||||....
cPvflqwldavhqlqrqfPtsfefneaflvklvqhtysclfGtflansekereeekvkertlsvWsllrakekeyrnllykekte
Pkinase_Tyr Protein tyrosine kinase 3013-3262 9.7e-47 149.1 Pfam-A 6-259 (259) alignment 
Range on Protein: 3013-3262
Range on HMM: 6-259/259.0
PIGEGGTATVYKGKWR------QSDVAIKLLKTDVVGSDfskvFAEYRREIFCLSSFIHDNILDLKGFCL--EPLAIITEFQSGGNLYDYIHDL-KNPLD
 .|||  ..|..|...      . .||.| || .   ..     .|  .|. ..... |.||. | |.|.  ||| |.||. .||.|......  |..|.
klGeGafGeVvegtlkgekekkevkVavKtlkeeaeeee....keefleeakimkklkhenivkllgvctkeepllivteyvegGdLlkfLrkkekeklt

WQLRIKIAKGIAASLQTLHDSRpsVVHRDLKSPNILLSSkdslTMECHLCDFSLSGFS-----TTVANRSVQNPVWLAPEVINNELCSDKSDVYAYGVIL
 . ....|  ||  .. |.. .  .||||| . |.||..    .. . ..|| |.        ... ...  .  |.|||..... .. ||||...||.|
ledllsfalqiAkGmeyLeskk..lvHrdLaarNvLlee....nkvvkisDfGLardiekddyykkkekaklpvkWmapEslkekkftsksDvWsfGvll

FELLSRTRFFSNITFMSEVEGLITEGVRPSLPSHNLPEYDSLLNICWAQDPTCRPSFIEITKKL
.|...  .   .    .||   ..|| | . |..  .|  .|.. ||...|. ||.| |...||
wEiftlgespypglsneevleklkegkrlekpencpeelyelmkqCweeepekRptfkelvekl
Pkinase Protein kinase domain 3013-3260 3.2e-42 134.4 Pfam-A 6-256 (260) alignment 
Range on Protein: 3013-3260
Range on HMM: 6-256/260.0
PIGEGGTATVYKGKWRQSD--VAIKLLKTDVVGSDFSKVFAEyrrEIFCLSSFIHDNILDLKGFCL--EPLAIITEFQSGGNLYDYIHdLKNPLDWQLRI
 .|.|. ..|||.|....   ||.| ||..   |. .|  .    |.  | .. |.||. | ...   . | ...|.  ||.|.|...  |..|...   
klGsGsfGkVykakekktgkkvAvKilkkeeekskkektalr...ElkilkklnHpnivkllevfeekdelylvleyveggdlfdllk.kkgklseeeik

KIAKGIAASLQTLHDSrpSVVHRDLKSPNILLSSKDSLtmecHLCDFSLSG---FSTTVANRSVQNPVWLAPEVIN-NELCSDKSDVYAYGVILFELLSR
|||. |. .|. ||.   ...|||||. ||||..|..|    ...|| |.     | . ..  |  . ..||||.. ..  . |.||...||||.|||..
kialqilegleylHsn..giiHrDLKpeNiLldekgel....kiaDFGlakkleksseklttlvgtreYmAPEvllkakeytkkvDvWslGvilyelltg

TRFFSNI---TFMSEVEGLITEGVRPSLPSHNL--PEYDSLLNICWAQDPTCRPSFIEITK
.  ||.    . .. ..   .. .. . |...   .|  .|.. ....||. |... || |
klpfsgeseedqlelirkilkkkleedepkssskseelkdlikkllekdpakRltaeeilk