Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
---|---|---|---|---|---|---|---|---|---|
0050432 | (Phosphotyrosine protein) phosphatases II | 74-476 | 2.2e-88 | 291.9 | In-house | 21-303 (308) | alignment | ||
Range on Protein: 74-476
Range on HMM: 21-303/308.0
LVDEERIKSSIYNLKNHIKCIHKIKEEFRLLEESVGPSETSEGDKKHNTSKNRYTNILPVNHTRVQLkkiqdKEGSDYINANYIDGA---YPKQFICTQG
.... .. .| .. .......|||. | . . |.| . .. | .||||..||| |.|| | .||||||||.|.|| .|..||.|||
vsslklsvldllkllekaldlglleeefeellsvkplleysvallpenkdkNrykdilpydhsRVkl.....degsdYInAsyvdgyssklprkfIatqg
PLPNTIADFWRMVWENRCRIIVMLSRESENCRIKCDRYWPEQIGGeqfsiygnGNEVFGTYSVELVEVIQdpEREIITRNIRLTF--EGETRDITQYQYE
|||||..||||||||...|.|||| .. || |.||..|||. .|| | ...| ..|.|... . . ....|...||. .||.| .|...|
PlpntvedFwrmvweqnvrvIvmLtklvengrekcaqYwplelgg........gsleygkftvtllseev..lddytvrtleltnlgdgesrtvthfhyt
GWPDHNIPDHTQPFRQLLHSITNRQnqiipssdRNVPIIVHCSAGVGRTGTFCTAVIMMKKLDHyfkqldatpidqvvdpfthlpiteyqsdnldlkglg
.||||..|...... ..|. . ... .. ||.|||||||||||||... ... |..
nWpdhgvPpspeilldflelvrksl........pggpivVHCsaGvGRtGtfialdllleqlek....................................
yhfkssiynsnginnnnnnnlnnnnninnnsngsnntpqtepnneeddddaaesdlkyaimdkynsRIDFNLFSIVLKLREQRPGMVQQLEQYLFCYKTI
...|..| ||||||||||| .|||||.|...
..................................................................eggvdvfeavkklReqRpgmvqtpeqylflyral
LDEIYHRL
|. .. .|
leylklkl
|
|||||||||
subfamily_ptpA1_pd | Subfamily ptpA1 | 75-492 | 4.6e-308 | 1015.5 | In-house | 1-418 (418) | alignment | ||
Range on Protein: 75-492
Range on HMM: 1-418/418.0
VDEERIKSSIYNLKNHIKCIHKIKEEFRLLEESVGPSETSEGDKKHNTSKNRYTNILPVNHTRVQLKKIQDKEGSDYINANYIDGAYPKQFICTQGPLPN
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
vdeerikssiynlknhikcihkikeefrlleesvgpsetsegdkkhntsknrytnilpvnhtrvqlkkiqdkegsdyinanyidgaypkqfictqgplpn
TIADFWRMVWENRCRIIVMLSRESENCRIKCDRYWPEQIGGEQFSIYGNGNEVFGTYSVELVEVIQDPEREIITRNIRLTFEGETRDITQYQYEGWPDHN
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
tiadfwrmvwenrcriivmlsresencrikcdrywpeqiggeqfsiygngnevfgtysvelveviqdpereiitrnirltfegetrditqyqyegwpdhn
IPDHTQPFRQLLHSITNRQNQIIPSSDRNVPIIVHCSAGVGRTGTFCTAVIMMKKLDHYFKQLDATPIDQVVDPFTHLPITEYQSDNLDLKGLGYHFKSS
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
ipdhtqpfrqllhsitnrqnqiipssdrnvpiivhcsagvgrtgtfctavimmkkldhyfkqldatpidqvvdpfthlpiteyqsdnldlkglgyhfkss
IYNSNGINNNNNNNLNNNNNINNNSNGSNNTPQTEPNNEEDDDDAAESDLKYAIMDKYNSRIDFNLFSIVLKLREQRPGMVQQLEQYLFCYKTILDEIYH
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
iynsnginnnnnnnlnnnnninnnsngsnntpqtepnneeddddaaesdlkyaimdkynsridfnlfsivlklreqrpgmvqqleqylfcyktildeiyh
RLNCKLGFSLPHVNNINN
||||||||||||||||||
rlncklgfslphvnninn
|
|||||||||
subfamily_PTPN6_pd | Subfamily PTPN6 | 80-332 | 5.2e-66 | 217.7 | In-house | 9-256 (306) | alignment | ||
Range on Protein: 80-332
Range on HMM: 9-256/306.0
IKSSIYNLKNHIKCIH--KIKEEFRLL--EESVGPSETSEGDKKHNTSKNRYTNILPVNHTRVQLKkIQDKEGSDYINANYIDGAYP---KQFICTQGPL
|.. . .|... . .. ..||| | ||. . .||.|..|..|||| ||||..|||| || .. ||||||||||... . |..| ||| |
ieqrvselekeeeslekagfeeefeelqqeeakkllsrkegakpenkeknryknilPfDhtrvilk.epsvpgsdyinanyikkevkgsdksyiatqgcl
PNTIADFWRMVWENRCRIIVMLSRESENCRIKCDRYWPEQiggeqfsiygNGNEVFGTYSVELVEViqDPEREIITRNIRL---TFEGETRDITQYQYEG
..|..|||||||.. .|.|||. .| | . || ||||.. . .| .|..||. |. . .. | |.... ....|.|.. ||...
ettvsdFWrmvwqensrvivmttkevErgkekCarYWPde..........eekeeyGkisvtnvse..ksladYilRelsvskkkkkkeerevfqyhfks
WPDHNIPDHTQPFRQLLHSITNRQNQIIPSsdRNVPIIVHCSAGVGRTGTFCTAVIMMKKLDH
||||..| ... . ..|. ....|... . .. ||.||||||.|||||| |..|.. .
WPdhgvpkdpgavLdfledvnrkqeeleea..eagpivvhCsaGiGRtGtfiviDillkliek
|
|||||||||
subfamily_eak_pd | Subfamily eak | 83-328 | 4.2e-16 | 53.2 | In-house | 20-261 (332) | alignment | ||
Range on Protein: 83-328
Range on HMM: 20-261/332.0
SIYN-LKNHIKCIHKIKEEFRLLEESvgpsetsEGDKKHNTSKNrYTNILPVNHTRVQLKKIQdKEGSDYINANYIDGA-YPKQFICTQGPLPNTIADFW
|.| ....|. .... . ||| .| |... . .| .|.| .. |.| | .. |||| .. . ...| | . . . ||
hiwnrinqrinivadlddyqrllsis.......etarleavnrn.vvkivpydrylvrltssq.lnrlGyinaslaefsevGrkyiltGiasedkvfafw
RMVWENRCRIIVMLSRESENCRIKCDRYWPEQiGGEQFSiygngnevFGTYSVELVEVIQDpeREIITRNIRLTFEGETRDITQYQYEGWPDHNIPDHTQ
.|| |.. ||.| . |. | |.|.|.. . |... || . || | .. . ||.. |. || . |.. || . ..| .
qmvleqkspaivqlledvelkleksdkyfpdk.treelk........fGildverkefvkr..niletrllelskGnethrvlhykvfGwtettlpkyed
--PFRQLLHS-----ITNRQNQIIPSSDR--------NVPIIvHCSAGVGRTGTFCTAVIMMK
.|. . . . ..... | . . ||| .. | |.|.| ....
flalrkvmkevGvlllivmksallsstlkkyihtppsfapii.qsarGsaraGvfvvidllir
|
|||||||||
subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 84-331 | 2.4e-69 | 228.8 | In-house | 11-241 (318) | alignment | ||
Range on Protein: 84-331
Range on HMM: 11-241/318.0
IYNLKNhiKCIHKIKEEFRLLEESVGPSETSEGDKKHNTSKNRYTNILPVNHTRVQLKKIQDKEGSDYINANYIDGAY-PKQFICTQGPLPNTIADFWRM
. .|.. . ...||. |. | . . . .. | ||||.|||. .||||.|......||||||||||||| |..| .|.|||.|| |||||
vrrlre..sGelllseeyerlsrseetvtslkslepvnkaknryanilaydhtrvkLqmlegeegsDyinanyidGyrrkkayiaaqaPlpetieDfWrm
VWENRCRIIVMLSRESENCRIKCDRYWPEQiggeqfsiygnGNEVFGTYSVELVEVIQDPEREIITRNIRLTFEGETRDITQYQYEGWPDHNIPDHTqpf
||| ...||||..|.|....|..||||.. | . .|. ||| | .. . . . ... | | |.|.. ||.| |||...|...
vWeqnsavivmltqeeergkakvhryWPsk...........gsrsygklvvelkeevelsdyvlrefkvtrteeeesrqvrqyhytsWpdegvpesg...
RQLLHSItnRQNQIIPSSDRNVPIIVHCSAGVGRTGTFCTAVIMMKKLD
.||. . || . . . . ||.|||||||||||.|.. |.....
aslldlv..rqvskaqqksgagpivvhCsaGvGrtGvfiavdillerik
|
|||||||||
0036941 | (Phosphotyrosine protein) phosphatases II | 85-478 | 5.2e-85 | 280.6 | In-house | 3-283 (297) | alignment | ||
Range on Protein: 85-478
Range on HMM: 3-283/297.0
YNLKNHIKCIHKIKEEFRLLEESVGPSETSEGDKKHNTSKNRYTNILPVNHTRVQLkkiqDKEGSDYINANYIDGAY-PKQFICTQGPLPNTIADFWRMV
..|............||. | . . ..| . .. | .||||..||| .||||.| |.||||||||.|.|| . ...||.||||||||..||||||
lkllekllflalllkefeellpllllgslsvallpenleknRykdilpydhtRVkl....ddegsdYinAsyvdgydlkrkfIatqgPlpntvedFWrmv
WENRCRIIVMLSRESENCRIKCDRYWPEQIGGEQFSiygngnevfGTYSVELVEVIQDPEREIITRNIRLTF--EGETRDITQYQYEGWPDHNIPDHTQP
||.....||||... |. |.||..|||. .|... | ..|.|..| .... ....|....|. .||.| .|...| |||||..|.....
weqnvtvIvmltelvelgrekcaqywpleegeslty.........gdftvtllsvevvllddytlrtlevtdtgngesrtvthfhytgwpdhgvpespas
FRQLLHSITNRQNQIipssDRNVPIIVHCSAGVGRTGTFCTAVIMMKKLDH--YFKQLDatpidqvvdpfthlpiteyqsdnldlkglgyhfkssiynsn
. .... . ...... .. |..|||||||||.|||..| .|. |.. . ...|
lldfielvrkvlkll....psggpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvd.........................................
ginnnnnnnlnnnnninnnsngsnntpqtepnneeddddaaesdlkyaimdkynsridfnLFSIVLKLREQRPGMVQQLEQYLFCYKTILDEIYHRLNC
....|.||||||||.||.||||.|.| ..|. ....|..
............................................................ileavkklReqRpgavqtleqyrflyeallellkkkltk
|
|||||||||
0039614 | (Phosphotyrosine protein) phosphatases II | 85-473 | 4.7e-83 | 274.4 | In-house | 22-290 (297) | alignment | ||
Range on Protein: 85-473
Range on HMM: 22-290/297.0
YNLKNHIKCIHKIKEEFRLLEESVGPseTSEGDKKHNTSKNRYTNILPVNHTRVQLKKIQDK-EGSDYINANYIDGAY--PKQFICTQGPLPNTIADFWR
..|... ........|| | . . . .|.. .. | .||||..||| .|.||.|| . . ..||||||.|.|| . ...||.||||||.|..||||
llllekansktllllefeellslkpd..ysiallpenkdknrykdilpydhsrvklkpedgvdldsdYinAsyvdgydlltrkfIatqgPlpetvedFwr
MVWENRCRIIVMLSRESENCRiKCDRYWPEQIGgeqfsiygngneVFGTYSVELVEVIQdpEREIITRNIRLTFEGETRDITQYQYEGWPDHNIPDHTQP
||||.....|||| .. |. | ||..|||| | ..|...|.|..|.. . ...|....| .||.| .|..|| |||||..|....
mvweqgvtvivmLtklvelgr.kcaqywpeegg............tygdftvtllkveh..ldgytvrtlevtnngesrtvthfqytgwpdhgvppslel
FRQLLHSITNRQNQIipssDRNVPIIVHCSAGVGRTGTFCTAVIMMKKLDhyfkqldatpidqvvdpfthlpiteyqsdnldlkglgyhfkssiynsngi
. ..|. . ..... ... |..|||||||||||||..| .|. |.
lleflelvrealael....pkggpvlVHCsaGvgRtGtfiaaylmleqle..................................................
nnnnnnnlnnnnninnnsngsnntpqtepnneeddddaaesdlkyaimdkynSRIDFNLFSIVLKLREQRPGMVQQLEQYLFCYKTILDEIY
.. .......| .|||||||.|| ..|| |.|. .|. .
....................................................keggvdvleavkelreqRpgavqtpsqyrflydallellk
|
|||||||||
0045450 | (Phosphotyrosine protein) phosphatases II | 85-470 | 1.4e-78 | 260.1 | In-house | 17-302 (307) | alignment | ||
Range on Protein: 85-470
Range on HMM: 17-302/307.0
YNLKNHIKCIHKIKEEFRLLEESVG--PSETSEGDKKHNTSKNRYTNILPVNHTRVQLKKIQDK-EGSDYINANYI--------DGA-YPKQFICTQGPL
. |............||. | . . |.|.. ...| .||||..||| .||||.|. .... |.||||||.|. || ...||.|||||
lvllllldfltgllkefekllsvtvfllgeysiallpenkdknrykdilpydhtRVklssldgsledsdYiNAsyvrvpllllldgydlkrkfIatqgPl
PNTIADFWRMVWENRCRIIVMLSRESENCRIKCDRYWPEQiggEQFSIYGNgnevfgtYSVELVEVIQdpEREIITRNIRLT---FEGETRDITQYQYEG
|.|..|||||.||.....||||... |. |.||..|||. ... ||| . |.|... . . ... |....| ..||.| .|...| |
petvedFwrmlweqgvtvivmltelvelgrekcaqywPde...geeltygn.......ftvtllseeh..ldgytvrtlevtdldgtgesrtvthfhytg
WPDHNIPDHTQPFRQLLHSITNRQNQIipssDRNVPIIVHCSAGVGRTGTFCTAVIMMKKLDHYfkqldatpidqvvdpfthlpiteyqsdnldlkglgy
||||..|...... .... . . ... ... |..|||||||||||||..| .|.. |..
wpdhgvppsfeelldfieevrkaleel....pkggpvlVHCsaGvgRtGtfiaaylmlrqleke....................................
hfkssiynsnginnnnnnnlnnnnninnnsngsnntpqtepnneeddddaaesdlkyaimdkynsrI---DFNLFSIVLKLREQRPGMVQQLEQYLFCYK
|..|...| .|||||||.|| .||| |.|.
..................................................................gtlldvdlleavkllreqRpgavqnpeqyrflye
TILD
.|.
alle
|
|||||||||
subfamily_PTPRD_pd | Subfamily PTPRD | 85-332 | 2.8e-78 | 259.0 | In-house | 8-243 (564) | alignment | ||
Range on Protein: 85-332
Range on HMM: 8-243/564.0
YNLKNHIKCIH-----KIKEEFRLLEESvGPSETSEGDKKHNTSKNRYTNILPVNHTRVQLKKIQDKEGSDYINANYIDG-AYPKQFICTQGPLPNTIAD
..||.|.. .. |..||.. .||. ..... .|..| .|||| ||.. .|.|| |.|.. .||||||||..||| .|..| |||||..||.|
aelkehvaklkansdlkfeeeykkieeg.qqftweaankpaNkaKNRyanivaYdhsRVvLskvegdegsDYINAsfidgyrkrkayIAtqgPlaetied
FWRMVWENRCRIIVMLSRESENCRIKCDRYWPEQiGGeqfsiygngnEVFGTYSVELVEVIQDPEREIITRNIRLTFEGETRDITQYQYEGWPDHNIPDH
|||||||.....||||.. .|. . ||..||||. | | .| . |.|.| . . || | ... . . |.| ..|... ||||..|..
FWRmvweqnsstiVmltkleEkgkvkchkYWPek.gt..........etygeltVtleeeeeladyeirtfklkkkkssesreVrqFhFtsWPdhgvpes
TQPFRQLLHSITNRQnQiipssDRNVPIIVHCSAGVGRTGTFCTAVIMMKKLDH
.... .|.. ... . . . . ||.|||||||||||||.. .|.... .
atslLdlirkvraln.e.....pdagPivVhCSaGVGRTGtfividamlerike
|
|||||||||
0047943 | (Phosphotyrosine protein) phosphatases II | 86-470 | 3.7e-83 | 274.4 | In-house | 3-270 (273) | alignment | ||
Range on Protein: 86-470
Range on HMM: 3-270/273.0
NLKNHIKCIHKIKEEFRLLEESVGPSETSEGDKKHNTSKNRYTNILPVNHTRVQLkkiqDKEGSDYINANYIDG-AYPKQFICTQGPLPNTIADFWRMVW
.| .. .......|||.|| . . ..| . ...| .||||..|||..|.|| | . .|||||||.|.|| ....||.||||||||..|||||||
lllekllgltllleefelllslkplltysvallpenkdknrykdilpydhsrvkl....gdggsdyinAsyvdgynlkrkfiatqgPlpntvedfwrmvw
ENRCRIIVMLSRESENCRIKCDRYWPEQiggeqfsiyGN-GNEVFGTYSVELVEVIQdpEREIITRNIRLTF--EGETRDITQYQYEGWPDHNIPDHTQP
|...|.|||| .. |. |.||..|||. |. ...| ..|.|... . . ...|...||. ||.| .|...| |||||..|.....
eqnvrviVmLtelvelgrekcaqYwple.........ggelsltygkftvtllseet..kddytvrtleltnlgtgesrtvthfhytgwpdhgvppsles
FRQLLHSITNRQNQIIPSsdrnVPIIVHCSAGVGRTGTFCTAVIMMKKLDHyfkqldatpidqvvdpfthlpiteyqsdnldlkglgyhfkssiynsngi
. .... . . ..... . |..|||||||||||||... ... | .
llefielvrkalealpsn....gpvvVHCsaGvgRtgtfialdllldqlek.................................................
nnnnnnnlnnnnninnnsngsnntpqtepnneeddddaaesdlkyaimdkynsRIDFNLFSIVLKLREQRPGMVQQLEQYLFCYKTILD
. ......| .||.||||||| .|||.|.|...|.
.....................................................eggvdvleavkllrsqRpgmvqtpeqyrflyealle
|
|||||||||
subfamily_PTPRN_pd | Subfamily PTPRN | 87-344 | 9.2e-47 | 154.2 | In-house | 21-266 (297) | alignment | ||
Range on Protein: 87-344
Range on HMM: 21-266/297.0
LKNHIKCIHKIKEEFRLLEES-VGPSETSEGDKKHNTSKNRYTNILPVNHTRVQLKKIQDKEGSDYINANYIDGAYPKQ--FICTQGPLPNTIADFWRMV
|..|.| .....|. | . || .. .....| .|||....|| .|.||.||. ...| |||||| | |.. .| |||||..|.||||.||
ledhlknkdrlekewealcayeaepstkevakaeknvkknrskavlpydhsrvklkeeasaeksdyinasaildhdprapayiatqgplastvadfwqmv
WENRCRIIVMLSRESENCRIKCDRYWPEQiggeqfsiygnGNEVFGTYSVELVE-VIQDPEREIITRNIRLTFEGETRDITQYQYEGWPDHNIPDHTQPF
||. . .||.|.| .|. .|.||||.. |.||.. | |.|| | . . . .. ||| .||. . ||....| ....
weqGvvvivnltrleeegvkqckrywpde...........GsevyhiyevhlvsehiwcddylvrsfylknlqtsetrtvtqfhflswpeegvPasaksl
RQLlhsiTNRQNQIIPSsdRNVPIIVHCSAGVGRTGTFCTAVIMMKKLDHYFKQLDAT-PIDQ
.. . |. | ||.||||.|.||||... .....| . |..| . ..
lef....rrkvnksyrG..rscpivvhcsdGaGrtGvyilidlvlnrllkGvkeidiaatleh
|
|||||||||
subfamily_Sponge-PTP3_pd | Subfamily Sponge-PTP3 | 87-169 | 9.7e-10 | 32.5 | In-house | 15-94 (95) | alignment | ||
Range on Protein: 87-169
Range on HMM: 15-94/95.0
LKNHIKCIHKIKEEFRLLEESVGPSETSeGDKKHNTSKNRYTNILPVNHTRVQLKKiqdKEGSDYINANYIDGAYPKQ-FICTQ
|. | . ... .||. . . | . | | . | |||. ||.| . ||| | | |||||| ..|| |. .|..|
lemhsnsdqefdnefksismtsgapytv.gsseanipknrflnifpydatrvvltt...krdsdyinacfvdgyarkncyiaaq
|
|||||||||
0051299 | (Phosphotyrosine protein) phosphatases II | 88-470 | 3.4e-86 | 284.5 | In-house | 16-284 (288) | alignment | ||
Range on Protein: 88-470
Range on HMM: 16-284/288.0
KNHIKCIHKIKEEFRLLEESVGPSETSEGDKKHNTSKNRYTNILPVNHTRVQLKKIQDKEGSDYINANYIDG-AYPKQFICTQGPLPNTIADFWRMVWEN
| . .......|||. | . . ..| . ...| .||||..||| .|.||.|. ... ||||||||.|||| ....||.||||||||..||||||||.
kllangltglleefeellsllpdltlsaallpenleknRysdilpydhsRVkLsvldgvegsdYinAsyidgynlkrkfIatqgPlpntvedFWrmvweq
RCRIIVMLSRESENCRIKCDRYWPEqiggEQFSIYGNgnevfgtYSVELVEVIQdpEREIITRNIRLT------FEGETRDITQYQYEGWPDHNIPDHTQ
..|.|||| .. |. |.||..|||. ... .||. ..|.|... . . ....|....| ..||.| .|...| .||||..||...
nvrvIvmltklvelgrekcaqYwpl....ggsltygd.......itvtllseev..lddytvrtlevtnldlldgdgesrtvthfhytnwpdhgvpdspe
PFRQLLHSITNRQNqiipssDRNVPIIVHCSAGVGRTGTFCTAVIMMKKLDhyfkqldatpidqvvdpfthlpiteyqsdnldlkglgyhfkssiynsng
.. ..|. . . .. ... |..|||||||||||||... ... |.
llldflrlvrkala......sgggpvvVHCsaGvgRtgtfialdllleqle.................................................
innnnnnnlnnnnninnnsngsnntpqtepnneeddddaaesdlkyaimdkynSRIDFNLFSIVLKLREQRPGMVQQLEQYLFCYKTILD
. ......| .|||||||||| .|||.|.|...|.
.....................................................keggvdvleavkrlreqRpgmvqtpeqyrfvyealle
|
|||||||||
subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 88-330 | 2.7e-55 | 182.7 | In-house | 15-243 (305) | alignment | ||
Range on Protein: 88-330
Range on HMM: 15-243/305.0
KNHIKCIHKIKEEFRLLEESvgPSETSEGDKKHNTSKNRYTNILPVNHTRVQLKKIQDKEGSDYINANYIDGAY-PKQFICTQGPLPNTIADFWRMVWEN
..... .........| | .. . | |..|..|||...| . .. |..|.. .... ||||||.|.|| |..| .||||.||.|||||...|
earvysdkgleaqykslyee..eesidvgkkeankaknrlkeitlldddriiltekeslddsdyinasyvdgykrkkkyivaqgPlkntvadfWrlivee
RCRIIVMLSRESENCRIKCDRYWPEQIGGeqfsiygngNEVFGTYSVELVEVIQDPerEIITRNIRLTF---EGETRDITQYQYEGWPDHNIPDHTQPFR
. . ||||.. |. . || .||||... .. || .|||| . . . . |.|...... . |.| ..||| |||| .|. . .
kvstivmltklveggkdkCrqYWpeskte.........kkefgefsvelksektas..dyieRklkisiededkesrtvlqyqltdWPdhGvpqfatsll
QLLHSITNRQNQiipssDRNVPIIVHCSAGVGRTGTFCTAVIMMKKL
.|.. ....|.. |..||..|||||||||||.|.. |.. .|
slikrvqkdqkk.....dkgvpllVhCsagvgRtGvfiavdialerl
|
|||||||||
subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 88-329 | 1.1e-47 | 157.3 | In-house | 13-242 (290) | alignment | ||
Range on Protein: 88-329
Range on HMM: 13-242/290.0
KNHIKCIHKIKEEFRLLEESVGPSETSEGDKKHNTSKNRYTNILPVNHTRVQLKKIQDKEG--SDYINANYIDG-AYPKQFICTQGPLPNTIADFWRMVW
..|.| .. ...| |. . . .. | . | .||..||.. . |. |..|.... .|||| ||.| ||.| ||||..||..|||...|
nghakgnegfrnqfkmldsgesehtvtvgltssnkllnRfanivvyddnritLrpisghkDCtneyinAcyikgykekkqyiatqgpvsntlvdFWkliw
ENRCRIIVMLSRESENCRIKCDRYWPEQigGeqfsiygngNEVFGTYSVELVEVIQDPerEIITRNIRLTFE---GETRDITQYQYEGWPDHNIPDHTQP
.... ||||| . |. . || |||.. . .. .| .|..|.. . |.|.|..... . |... .|||| |... ..|
qekvtiivmltniieegkvkCqqYWpds..d.........tkaygefsikllneetln..eyierklevknknsagakqsvtqyqitnwdstgkvtnpqt
FRQLLHSITNRQNQiipssDRNVPIIVHCSAGVGRTGTFCTAVIMMKK
.... ... | . . | .|.||||..|||...||.| . ..|
illvieemyktqrk.....rgntsivvHCSdtvgrsavfcaaattink
|
|||||||||
subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 88-329 | 1.6e-46 | 153.6 | In-house | 13-237 (287) | alignment | ||
Range on Protein: 88-329
Range on HMM: 13-237/287.0
KNHIKCIHKIKEEFRLLEE-SVGPSETSEGDKKHNTSKNRYTNILPVNHTRVQLKkiqdKEGSDYINANYIDGAY-PKQFICTQGPLPNTIADFWRMVWE
|.| | |. | .||. . . | . ..| |||.|.||. . || || .| ||||| .||| |.|| ...|. ||. .||.....
kghakgnegfknqftvleqvtqredevthniasqnkdknRltqilvpdnyrvllk....gehpdyinavfidgykekkafiiaesPmfntarnfWklidd
NRCRIIVMLSRESENCRIKCDRYWPEQiggeqfsiygnGNEVFGTYSVELVEviQDPEREIITRNIRLTFEG---ETRDITQYQYEGWPDHN-IPDHTQP
.. .||||..| || . .| .||||. . |.| |..||.. .. . . | |..... .. ... ..|||. |... ....
rnvtaivmlcqekendeevcyqyWpee...........ksvvlGeynielln..eevnagyierklevknknkagdkqqvkqyqitnWdstgkvtepqti
FRQLlHSITNRQNQiipssDRNVPIIVHCSAGVGRTGTFCTAVIMMKK
. .. . | . | .|.||||..|||...|| | . ..|
llvi.eemyktqrk.....rgntsivvhCsdtvGrsamfcaaattink
|
|||||||||
0043336 | (Phosphotyrosine protein) phosphatases II | 89-333 | 3.9e-72 | 238.3 | In-house | 14-240 (278) | alignment | ||
Range on Protein: 89-333
Range on HMM: 14-240/278.0
NHIKCIHKIKEEFRLLEESVGpSETSEGDKKHNTSKNRYTNILPVNHTRVQLKKIQDKEGSDYINANYIDGAY-PKQFICTQGPLPNTIADFWRMVWENR
. .. .....|| | . ..| . ...| .||||..||| .|.||.|. .. ..||||||.|.|| |..||.||||||.|..||||||||..
lllnlktllllefeellsfkl.dtysiallpenkdknrykdilpydhsrvklsllggdldsdYinAsyvdgynvprkfiatqgPlpetvedFwrmvwelg
CRIIVMLSRESENCRIKCDRYWPeqiggeqfsiygNGNEVFGTYSVELVEVIQdpEREIITRNIRLT--FEGETRDITQYQYEGWPDHNIPDHTQPFRQL
...|||| .. |. |.||..||| .| ...|...|.|..... . ...|....| .||.| .|.|.| |||||..|...... ..
vttivmLtelvelgrvkcaqYwp............ggsltygdftvtllkeeh..lddytvrtlevtnlgdgesrtvthyhylgwpdhgvpeslsllldf
LHSITNRQNqiipssDRNVPIIVHCSAGVGRTGTFCTAVIMMKKLDHY
|. . .... |.| |..|||||||||||||... ... |...
lkavreale......dsngpvlVHCsaGvgRTGtfialyllleqleke
|
|||||||||
subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 89-330 | 1.4e-66 | 219.8 | In-house | 12-243 (319) | alignment | ||
Range on Protein: 89-330
Range on HMM: 12-243/319.0
NHI-----KCIHKIKEEFRLLEESVGPsETSEGDKKHNTSKNRYTNILPVNHTRVQLKKIQDKEGSDYINANYIDGAY-PKQFICTQGPLPNTIADFWRM
... . .....||.||.|.| .... .|..| .||||.|||....|||.|......||||||||..||| ..|| ||.|| ||| |||||
erlkalastgetllekefkllkeavnd.tfdsaskeenkkknryqnilaydrtrvvlseldgvegsdyinasfidgyqerekfiatqaPlentiedfWrm
VWENRCRIIVMLSRESENCRIKCDRYWPEQiggeQFSIYgngnevfGTYSVELVEVIQdpEREIITRNIR---LTFEGETRDITQYQYEGWPDHNIPDHT
|||... |.|||.. .|. ..|. .||||. .| | | . |.| | . ..| |.. .. | |||.....||. ||||..|...
vWeeessivvmltklveklkvklkkywpee....nfeey.......Grlivtleeeee..ledyiirklklnkkssevetRevkhfqyteWpdhdvPeka
QPFRQLLHSITNRQNQiipssDRNVPIIVHCSAGVGRTGTFCTAVIMMKKL
. .||. | . ... . ||.|||||||||||||.. .|. ..
tslldllkrirksrek.....tqsgPivvhCsaGvGRtGtfivldamlerv
|
|||||||||
subfamily_PTPRK_pd | Subfamily PTPRK | 89-329 | 2.3e-56 | 185.9 | In-house | 11-236 (314) | alignment | ||
Range on Protein: 89-329
Range on HMM: 11-236/314.0
NHIKCIHK-----IKEEFRLLEESvgpseTSEGDKKHNTSKNRYTNILPVNHTRVQLKKIQDKEGSDYINANYIDGA-YPKQFICTQGPLPNTIADFWRM
..|..... .|||. | | |..| .|||...||. ...||.|. |.. ||||||..||. |..|| |||||..|..||||.
qsiallkraegygfkeeyeslfeg.....wdaakkdenreknrsgdilaydrsrvflitidgdpssdyinaalidsykrpaafivtqgPlqetvkdfWrl
VWENRCRIIVMLSRESENCRIKCDRYWPEQiggeqfsiygngNEVFGTYSVELVEViqDPEREIITRNIRLTF----EGETRDITQYQYEGWPDHNIPDH
|....| ||||. |. |.|| .||||. ||.| |||||. ... |...| |.. |.| . |.|. |||||..| .
vydencasivmltelvevgrvkClkyWPed............tevygdikvelvet..ellaelvvrifrveklargqeeirevrqfqflgWpdhdvPvs
TQPFRQLLHSITNRQNQiipssdRNVPIIVHCSAGVGRTGTFCTAVIMMKK
. . .|.. . . |.. .. .|.|||||| ||||||.. |..
atgllklvrrvkksqee......eaGrivvhCsaGaGrtGtfiaidivldm
|
|||||||||
0040438 | (Phosphotyrosine protein) phosphatases II | 92-486 | 1e-83 | 276.6 | In-house | 15-290 (317) | alignment | ||
Range on Protein: 92-486
Range on HMM: 15-290/317.0
KCIHKIKEEFRLLEESVGPsETSEGDKKHNTSKNRYTNILPVNHTRVQLKKIQDKEGSDYINANYIDGAY-PKQFICTQGPLPNTIADFWRMVWENRCRI
. ....|||. | . . ..|.. .. | .||||..||| |.||.|. .. ..||||||.|.|| . ...||.||||||||..||||||||.....
sdftalleefedllslkld.tysvaelpenkdknrypdilpydhsRVkLsplggdldsdYInAsyvdgpnlkrkfIatqgPlpntvedFwrmvweqgvtv
IVMLSRESENCRIKCDRYWPEqiggEQFSIYgngnevfGTYSVELVEVIQdpEREIITRNIRLT--FEGETRDITQYQYEGWPDHNIPDHTQPFRQLLHS
|||| .. |. |.||..|||. ... | |...|.|..... . .|. |..... ..|.| .|...| |||||..|...... ..|.
ivmLteleelgrekcaqYwpl....getlty.......gdftvtllseee..lagitlrtlevedlgdsesrtvthfhytgWpdhgvppspdllldflea
ITNRQNqiipssDRNVPIIVHCSAGVGRTGTFCTAVIMMKKLDhyfkqldatpidqvvdpfthlpiteyqsdnldlkglgyhfkssiynsnginnnnnnn
. . .. |.. |..|||||||||||||..| .|. |.
vreale......dpggpvlVHCsaGvgRtGtfiaaylmleqle.........................................................
lnnnnninnnsngsnntpqtepnneeddddaaesdlkyaimdkynSRIDFNLFSIVLKLREQRPGMVQQLEQYLFCYKTILDEIYHRLNCKLGFSLPH
. .......| .|||||||.|| .||| |.|. .|. ....|... .|..
.............................................keggvdveeavkelreqRpgavqtpeqyrflydalleylkrkltlepaselkl
|
|||||||||
subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 92-330 | 1.7e-55 | 183.3 | In-house | 24-250 (298) | alignment | ||
Range on Protein: 92-330
Range on HMM: 24-250/298.0
KCIHKIKEEFRLLEESV---GPSETSEGDKKHNTSKNRYTNILPVNHTRVQLKKIQDKEGSDYINANYIDGAYP-KQFICTQGPLPNTIADFWRMVWENR
| . . ..||. |.. |.. . |..| .||||..|......|| |.|....| |||||| ..... . || ||.||..|..||||||.|.
kkltgyalefqrlnsvsseieeeekevarkpenkkkNRyadiialdssRvvLekedadeesdYiNAsflhaykgrnafiatqaPltetvedFWrmvteed
CRIIVMLSRESENCRIKCDRYWPEQiggeqfsiygnGNEVFGTYSVELVEVIQDPEREIITRNIRLTFEGETRDITQYQYEGWPDHNIPDHTQPFRQLLH
|||| | ..|. .|||.. |.| .|. .|.| . . . .. . .. . | ..| . | .. |||. .| ... .||.
igtiVmltnleeldktkyhkywPde...........gketygeitvsllskeefadlivrklkvskkkeekerevrqlhftsWpdkgvpenatsvldllr
SITNRQNQiipssDRNVPIIVHCSAGVGRTGTFCTAVIMMKKL
. |.| |.|.||.|||||||.|||. .. ..
kvrasqqq.....agnkpvivqCsaGvgRsGtfiaidsvlerv
|
|||||||||
subfamily_Cele-PTP-6_pd | Subfamily Cele-PTP-6 | 92-330 | 1e-45 | 151.1 | In-house | 13-236 (307) | alignment | ||
Range on Protein: 92-330
Range on HMM: 13-236/307.0
KCIHKIKEEFRLLEESVgPSETSEGDKKHNTSKNRYTNILPVNHTRVQLKkiQDKEGSDYINANYIDGA-YPKQFICTQGPLPNTIADFWRMVWENRCRI
| ......||| | . | . . || ||||... ....|. .| | |||| |||. | ||.|||.|||| ||. .|| |. ...
kgvqalvdefrvlakkt.pegvtveafsantdknryqdvkcqdkgrivvk..fdglasdyihanylgiaikpkkficaqgplentqysfwamaiqekves
IVMLSRESENCRIKCDRYWPEQIGgeQFSIYGNGNEVFGTYSVELVEVIQDpEREIITRNIRLTFEGETRDITQYQYEGWPDHNIPDHTQPFRQLLHSIT
..|| . | ..|||..||| . | | ..|. .. . .. | | | .... . ...| |...|.| |||. .|. ||...
vimlckvielakikceqywpleeg..qklvfgeapntisvanlgakklapd.edlinvttlkvdwaqksrtiqhlqwenwpdrgvpqinltainlleavr
NRQNqiipssdrnvPIIVHCSAGVGRTGTFCTAVIMMKKL
.| |..|||||||||.|| . ... |.
ydtn..........pvvvhcsaGvGrsGtivaislvqdkm
|
|||||||||
subfamily_Cele-PTP-10_pd | Subfamily Cele-PTP-10 | 93-331 | 3.4e-34 | 112.9 | In-house | 22-249 (305) | alignment | ||
Range on Protein: 93-331
Range on HMM: 22-249/305.0
CIHKIKEEFRLLEESVGPSETSE-----GDKKHNTSKNRYTNILPVNHTRVQLKKIQdkeGSDYINANYIDGAY--PKQFICTQGPLPNTIADFWRMVWE
..|..|||| | | | . . .||||... ... |.|.| . |||| |||. |.|||.|||| .|| .|| || .
gvdklreefrglakytrpdmtqvafnanqsadiaitknryqdvpcqdqsavkldkps...psdyihanyvgcpmipekrficaqgpldqtidefwwmviq
NRCRIIVMLSRESENCRIKCDRYWPEQIGgEQFSIYGN--GNEVFGTYSVElveviQDPEREIITrnIRLTFE-GETRDITQYQYEGWPDHNIPDHTQPF
|. |||| . | ..|| .||| | |. .. . ..| |. .| .|.| .| . ..||. ... . . |. ||| .|
nkveqivmlcktvelgklkcaqywpaaqg.eklelksgivvenvsgskpme.....rdaeiqitl..lnltysgdqkmsvrhlqwtewpdrgvppcklts
RQLLHSITNrqnqiipsSdrNVPIIVHCSAGVGRTGTFCTAVIMMKKLD
.|| .| | .|||.||||||.||||| . ...|.
lellsairg........s..kvpivvhcsagigrtgtivaieyilekia
|
|||||||||
subfamily_egg_pd | Subfamily egg | 93-327 | 1e-25 | 85.1 | In-house | 12-225 (307) | alignment | ||
Range on Protein: 93-327
Range on HMM: 12-225/307.0
CIHKIKEEFRLLEESVGPSETSEGDKKHNTSKNRYTNILPVNHTRVQLKKIQDKEGSDYINANYIDGA-YPKQFICTQGPLPNTIADFWRMVWENRCRII
. ... . .||||| . .. | | | . . .||.|. . . |.| ||...| .||..| || || ||||||...... |
ivqelerrlevleesvdeislttaasdnnlekarskrvhckdssrvklelrrGqylddfihanrvkGkpllnefilaqaplkntvddfwrmvfqeevqyi
VMLSRESENcrIKCDRYWPEQIGGEQfsiygngNEVFGTYSVELVEVIQDPEREIITRNIRLtfEGETRDITQYQYEGWPDHNIPDHTQPFRQLlHSItn
|||. |. .|. ||| | |.. .| ..| . .. ...| | .. .. . .| | |.| | .
vmltsrkes..erceyywpkaesdsl.......vtvpGslrienlkvdskadplfrvtklkl..vGgddeerflehwqgdvnnssdvysplrvl.rkl..
RQNqiipssdrNVPIIVHCSAGVGRTGTFCTAVIMM
|. |..|.. || ...|. .. | .
rnl........skpvvvqdilGvskaatlvaieial
|
|||||||||
subfamily_PTPRG_pd | Subfamily PTPRG | 94-332 | 1.5e-58 | 193.4 | In-house | 18-249 (563) | alignment | ||
Range on Protein: 94-332
Range on HMM: 18-249/563.0
IHKIKEEFRLLEESVGPS--ETSEGDKKHNTSKNRYTNILPVNHTRVQLKKIQDKEGS-DYINANYIDGAY-PKQFICTQGPLPNTIADFWRMVWENRCR
....||| |.. . .. ... .|..| ||||.||......||.|... .|... |||||||||| . |.|| |||||..|. |||||.||..
digfseefealqsetiskdldaehsqkpenkrKnRylnivaydrsRvklsplpgkkkklDYinAnyidGyqkskafiatqgplkdtfddFWrmiWeqnva
IIVMLSRESENCRIKCDRYWPE--QIGGEQFSIYGNGNEVFGTYSVElveviqdperEIITRNIRLTFEG---ETRDITQYQYEGWPDHNIPDHTQPfrq
||||.. |. | |||.|||. . ..... .||. .|.|. ... .|..| . . . ..||.| ||||. |.|. |
iivmitnlvergrrkcdvYWPkdesetygalqvtlieeevlalytvr..........tlviknlklkkkkqcdteklvrqyhytkWPdhgvPehslp...
LLHSITNRqnqIIPSSDRNVPIIVHCSAGVGRTGTFCTAVIMMKKLDH
| . . . ||.||||||||||||.. ..|.. .
vLifvkks...saankaeaGPivvHcsaGvgrtGtyivldtllkqiqq
|
|||||||||
subfamily_PTPRA_pd | Subfamily PTPRA | 94-330 | 4.7e-53 | 175.2 | In-house | 31-255 (330) | alignment | ||
Range on Protein: 94-330
Range on HMM: 31-255/330.0
IHKIKEEFRLLEESVGPSETSEGDKKHNTSKNRYTNILPVNHTRVQLKKIQDKEGSDYINANYIDGAYPK-QFICTQGPLPNTIADFWRMVWENRCRIIV
....||| | . . .|. | |||. |||| ...|| | ... .| |||||| .||| | .|| .|||. .|. |||||.|| . ||
nklfreefnalPagpiqatlelaskeenkeknrvvnilPydfsrvilsvkeGveesdyinasfidGykekdkfiaaqGPkeetvedfwrmiweqksativ
MLSRESENCRIKCDRYWPEQigGeqFSIYGNGnevfgTYSVELVEVIQDP-EREII-TRNIRLTFEGETRDITQYQYEGWPDHNIPDHTQPFRQLLHSIT
||. | . || .|||.. | ||| . .|| ..|..| |... .. | | ..| ..|. ...||| .| ... .||. .
mltelkerkeekcaqywPde..G..lvtyGni.....rvevedetvlvdytvrkflvqqlpdatrekksrlvrqfhftswPdvGvPfepiGmlkllkkvk
NRQNQiipssDRNvPIIVHCSAGVGRTGTFCTAVIMMKKL
. ..| . ||.|||||||||||||.. .....
klnqq.....sag.pivvhcsaGvGrtGtfivldavlerv
|
|||||||||
subfamily_Sponge-PTP9_pd | Subfamily Sponge-PTP9 | 94-325 | 4.6e-40 | 132.2 | In-house | 14-248 (301) | alignment | ||
Range on Protein: 94-325
Range on HMM: 14-248/301.0
IHKIKEEFRLLEESVgPSETSEGDKKHNTSKNRYTNILPVNHTRVQLKKIQ--DKEGSDYINANYIDGAYP-KQFICTQGPLPNTIADFWRMVWENRCRI
.|..|... |.| . ... | ...|. ||. || .... |. ||. . |. .||||.|||| |.|| .|||. .|..||||..|...
snkfeeqykelkege.dksctvglseenkalnrfknitvyddnriilkpkpnldlcqreyinasyidgysekkkfiaaqgpmkktlvdfWrliwqekpvs
IVMLSRESENCRIKCDRYWPEQI----GGEQFSIYGNGNEVFGTYSVELVEV-IQDPER-EIITRNIRLTFEGETRDITQYQYEGWPDHNIPDHTQPFRQ
|||. . |. . || .|||. .|.. . . |. . . . | ||| | |... . . ...|..|.| ||.. . . |
ivmvtnlkegtkskceqywpnseaeseefgpftvtlvneqvyPdfvirqlnvkiqdgsnngyierkfkvksdksswdvlqlqvtdWpqdGvvreprtvLq
LLHSITNRQNQIipssdRNVPIIVHCSAGVGRTGTFCTAVI
.. . ||..| |..||||..|.|.|..|. |
viddvihrqqki.....gggpvvVHCSdtVsrsGvYcsvsi
|
|||||||||
subfamily_Cele-PTP-14_pd | Subfamily Cele-PTP-14 | 94-333 | 1.6e-32 | 107.3 | In-house | 26-253 (310) | alignment | ||
Range on Protein: 94-333
Range on HMM: 26-253/310.0
IHKIKEEFRLLEESVGPSETSEGDKKhNTSKNRYTNILPVNHTRVQLKkIQDKEGSDYINANYIDGAYPK-QFICTQGPLPNTIADFWRMVWENRCRIIV
|. . ..| |. .| | | || . ||||.... . .||.|| |. ||| |||. | . |||.|||| || |||||....|. |.
ieglvkqyrkldakqdssltyeaykk.ymhknrysdvvcldtsrvklk.idksryedyihanyvktnylrstficsqgplqhtiidfwrmifqeraesil
MLSRESENCRIKCDRYWPEQIGGEQFSIYGNGN--EVFGTYSVELVEVIQDPEREIITRNiRLTFegETRDITQYQYEGWPDHNIPDHTqpfrqlLHSIT
.| . .|. | || ||| | . | | . . . | |. . . . . .. .. ||| .|| |..
llckvgeegrpkcvgywpslgvtetygcirvtnlsesseefeicnlavtfvpdnvpvdeq.panl..kelrvslikwpnwpdrgvpdek......chtvp
NRqnqiIPSSDRNVPIIVHCSAGVGRTGTFCTAVIMMKKLDHY
.| . . | | .||||||..|... .. . ..|||.
qr....llaqvrhgpcvvhcsagkdrlyvvvalklkidkldrg
|
|||||||||
subfamily_PTPRB_pd | Subfamily PTPRB | 95-332 | 7.7e-72 | 236.8 | In-house | 25-247 (293) | alignment | ||
Range on Protein: 95-332
Range on HMM: 25-247/293.0
HKIKEEFRLLEESVGPSETSEGDKKHNTSKNRYTNILPVNHTRVQLKKIQDKEGSDYINANYIDGA-YPKQFICTQGPLPNTIADFWRMVWENRCRIIVM
....||. |.. ... ... |..||||||||| .|.||.|....|..||||||||||.| |..|| ||||||.|. ||||||||....||||
lrfseeyeelkavgkdqavkaaelavnraknrytnilpydhsrvkLaalkdesgsDYinanyipgynsprefiatqGPlpetvddfWrmvwekkssiivm
LSRESENCRIKCDRYWPEQiggeqfsiygNGNEVFGTYSVELVEVIQdpEREIITRNIRLTFEGETRDITQYQYEGWPDHNIPDHTQPFRQLLHSITNRQ
| . |. ..||..|||.. . . ..| .|.||. . .. ..|..... | |.|...||.. ||||..|..|... .... . ...
ltqlvekgkvkCeeYWPad..........eepvlyGdikvtlvaeee..ledwvirelkiekekeerkvrqyhftsWpdhgvPektktlldfvrtvreai
NQiipsSDRNVPIIVHCSAGVGRTGTFCTAVIMMKKLDH
.. . .. ||.||||||||||||| . .......
ek....taskrPivvhCsaGvGRtGtfialdrllqaiee
|
|||||||||
subfamily_PTPN9_pd | Subfamily PTPN9 | 95-333 | 1.1e-61 | 203.5 | In-house | 16-253 (297) | alignment | ||
Range on Protein: 95-333
Range on HMM: 16-253/297.0
HKIKEEFRLLEESVGPSETSEGDKKHNTSKNRYTNILPVNHTRVQLKKIQDKEGSDYINANYIDGA-YPKQFICTQGPLPNTIADFWRMVWENRCRIIVM
. ...|. . . . .. | .|||||..| ...|||.|.|....| |||||||..|| .| || |||||..|. ||||||||.....|||
rGlskeyaeirnepveGtflasklranleknrytdvlcydetrvvlakvdedeasdyinanfvdGykqkkafiatqGplkktvsdfWrmvWeqevlvivm
LSRESENCRIKCDRYWPEQIggeqfsiygNGNEVFGTYSVELVEVIQDPEREIITRNIRLTFEGETRDITQYQYEGWPDHNIPDHTQPFRQLLHSITNRQ
| |. |.|| .|||.. . . || .||. ||| . . .. . .|. . ..|.| .| .|. .|||. .|. .. . ..|. . ..|
ttrvvergrlkcgqyWplee.........essaefgdlsvsnveveeeedykvrvleiknvkteesrkvthfqflsWPdyGvPssaaslldvlekvrekq
NQIIPS-------SDRNVPIIVHCSAGVGRTGTFCTAVIMMKKLDHY
... . .. ||.||||||.||||||.| | ...|..
alavkelgdewkghpsgPPivvhcsaGiGrtGtfitldiclsrleev
|
|||||||||
subfamily_Ptp69D_pd | Subfamily Ptp69D | 95-331 | 1.9e-59 | 196.3 | In-house | 22-247 (307) | alignment | ||
Range on Protein: 95-331
Range on HMM: 22-247/307.0
HKIKEEFRLLEESVGPSETSEGDKKHNTSKNRYTNILPVNHTRVQLKKIQDKEGSDYINANYIDGA-YPKQFICTQGPLPNTIADFWRMVWENRCRIIVM
. ...|.. ||.. . .|. ..|| |. |||| .| . ..|||.||||. || ||||||..| | |.||. |.|. .|| |||||..| .|||
fglakeyekLeareidkstkvsekkenalknRyedikafDktRvkLkkingkedsdYinasfikgykekkkfiaaqdPveatigDfWRmiaeqevtlivm
LSRESENCRIKCDRYWPEQiggeQFSIYGngnevfgTYSVELVEviQDPEREIITRNIRLTFEG-------ETRDITQYQYEGWPDHNIPDHTQPFRQLL
|| ..| | ||..|||.. . || |.||. .. . | |.. .. . ..| ..||.| ||.| ..|.... .|.
lsnlteknrkkcakYWpie....devqyg.......dilvklvs..eekhsdyiiReldvskkkeesgevedsrkvvqyhytgWkDskvPevargllkli
HSITNRQNQIipssdrNVPIIVHCSAGVGRTGTFCTAVIMMKKLD
. . . ... . ||.|||||||||.|.| . .....|
eqvrelykln......rsPivvhCsaGvgrsgifvaldsllqqlk
|
|||||||||
DSPc_SM00195 | 96-472 | 5.1e-116 | 382.0 | In-house | 1-262 (263) | alignment | |||
Range on Protein: 96-472
Range on HMM: 1-262/263.0
KIKEEFRLLEESVGPSETSEGDKKHNTSKNRYTNILPVNHTRVQLKKIQDKEGSDYINANYIDGA-YPKQFICTQGPLPNTIADFWRMVWENRCRIIVML
|.||||. |||| |.||.|..||.|.|||||.||||..||||.|||...||||||||||||.|| ..|..|.||||||.|..||||||||....|||||
klkeefekleestspketteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivml
SRESENCRIKCDRYWPEQIggeqfsiygNGNEVFGTYSVELVEVIQDPeREIITRNIRLTFEG--ETRDITQYQYEGWPDHNIPDHTQPFRQLLHSITNR
..|.||...||||||||.. .|.|.||..||.||||.... .|||.|...||.|| |||..|||||..||||..||.|.....||......
teeeengkekcdrywpees.........ggketfgkisvklvevekkk.deiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkks
QNQIipssdrNVPIIVHCSAGVGRTGTFCTAVIMMKKLDHYFKqldatpidqvvdpfthlpiteyqsdnldlkglgyhfkssiynsnginnnnnnnlnnn
.... ..||.|||||||||||||.|. |...||....|
ksts......sgpivVhCsaGvgRtgtfvtidiilskleeekk.........................................................
nninnnsngsnntpqtepnneeddddaaesdlkyaimdkynsridFNLFSIVLKLREQRPGMVQQLEQYLFCYKTILDEI
...|.|| .||.|||||||.||||||.|..||. |
.............................................vdifeivkelRkqRpgmvqtleqYlfiyeaileyi
|
|||||||||
PTPc_SM00194 | 96-472 | 5.1e-116 | 382.0 | In-house | 1-262 (263) | alignment | |||
Range on Protein: 96-472
Range on HMM: 1-262/263.0
KIKEEFRLLEESVGPSETSEGDKKHNTSKNRYTNILPVNHTRVQLKKIQDKEGSDYINANYIDGA-YPKQFICTQGPLPNTIADFWRMVWENRCRIIVML
|.||||. |||| |.||.|..||.|.|||||.||||..||||.|||...||||||||||||.|| ..|..|.||||||.|..||||||||....|||||
klkeefekleestspketteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivml
SRESENCRIKCDRYWPEQIggeqfsiygNGNEVFGTYSVELVEVIQDPeREIITRNIRLTFEG--ETRDITQYQYEGWPDHNIPDHTQPFRQLLHSITNR
..|.||...||||||||.. .|.|.||..||.||||.... .|||.|...||.|| |||..|||||..||||..||.|.....||......
teeeengkekcdrywpees.........ggketfgkisvklvevekkk.deiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkks
QNQIipssdrNVPIIVHCSAGVGRTGTFCTAVIMMKKLDHYFKqldatpidqvvdpfthlpiteyqsdnldlkglgyhfkssiynsnginnnnnnnlnnn
.... ..||.|||||||||||||.|. |...||....|
ksts......sgpivVhCsaGvgRtgtfvtidiilskleeekk.........................................................
nninnnsngsnntpqtepnneeddddaaesdlkyaimdkynsridFNLFSIVLKLREQRPGMVQQLEQYLFCYKTILDEI
...|.|| .||.|||||||.||||||.|..||. |
.............................................vdifeivkelRkqRpgmvqtleqYlfiyeaileyi
|
|||||||||
subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 96-332 | 1e-63 | 210.1 | In-house | 22-241 (288) | alignment | ||
Range on Protein: 96-332
Range on HMM: 22-241/288.0
KIKEEFRLLEESVGPSETSEGDKKHNTSKNRYTNILPVNHTRVQLKKIQDKEGSDYINANYIDGAY-PKQFICTQGPLPNTIADFWRMVWENRCRIIVML
..||.. | . .... | . .| .|||| ||||....||.||| ....|.|||||.|||| |..|.|||||..|. |||..|.||. ||||
gfseeynsLaalektksvtagrlavnakknRyrnilpyDekrvklkkleeeagaDYinasyidgekkkkkyiatqgPladtvndfWelvyenktstivml
SRESENCRIKCDRYWPEQiggeqfsiygNGNEVFGTYSVELVEVIQdpEREIITRNIRLTFEGETRDITQYQYEGWPDHNIPDHTQPFRQLLHSITNRQN
. |. . ||..|||.. . .. .| |.|||. . . ....|.. | ... ..|||||| .||||..|. ..|. .||. . . ..
telveggktkCeeYWPda..........dkpknyGsvtvtlveske..ledfvlrklllekkkteleitqyqylaWpdhgvPeskapllellrqvkvanq
QIipssdrNVPIIVHCSAGVGRTGTFCTAVIMMKKLDH
. |||||||||||||||| .. .......
ad......tgpiivhCsaGvGrtgtFialdalidavee
|
|||||||||
subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 96-333 | 3.2e-55 | 182.7 | In-house | 35-254 (319) | alignment | ||
Range on Protein: 96-333
Range on HMM: 35-254/319.0
KIKEEFRLL-EESVGPSETSEGDKKHNTSKNRYTNILPVNHTRVQLKKIQDKEGSDYINANYIDGAY-PKQFICTQGPLPNTIADFWRMVWENRCRIIVM
|.. ||| . . .| .. . . ..| |||..|||. ....|.|.... .|.|||||| ...| ....| .||||.||.||||||.|| .| ||.
klevefrracklgvnladqtfanldqnkdknriinilafdknvvklerliGeefsdyinasfvtGyqrkdkyiaaqGPldntladfWrmiweyncstivl
LSresencRIKCDRYWPEQIGGEqfsiYGNGNevfgtYSVELVEVIQDpereIITRNIRLTF---EGETRDITQYQYEGWPDHNIPDHTQPFRQLLHSIt
|. . || .||| .| . ..... .|..|| .. . |.|.|. | . |.|||. . ||||. ||.. .. .|.. .
lt......kdkcsqywplkivik....eerfk.....vkvdsveetae....yvvrdielsedgkekdirkitqfhflGwpdvGvpdypsdlmrlvkkv.
nrqNQIIPSSDRNVPIIVHCSAGVGRTGTFCTAVIMMKKLDHY
. . . . .|.|||||||||||.. . ........
...rhltskenhranivvhcsaGvGrtGvyivldvlldrmkee
|
|||||||||
subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 96-331 | 2e-47 | 156.4 | In-house | 11-238 (287) | alignment | ||
Range on Protein: 96-331
Range on HMM: 11-238/287.0
KIKEEF-RLLEESVGPSE-TSEGDKKHNTSKNRYTNILPVNHTRVQLKKiQDKEGSDYINANYIDGA-YPKQFICTQGPLPNTIADFWRMVWENRCRIIV
....|. .| |.| . . . .. ...||||...||...||| | . . . |||||||||. . ..||..|||.. |. ||||.|.|.| ..
dvdkevdalkedsesstatfkaaeelaavkknryadvlPiddtrvllsa.egelGsdyinanyvasytddeafiaaqgPiaatvrdfwravletrsasvi
MLSRESENCRIKCDRYWPEQiggEQFSiygngneVFGTYSVELVE-VIQDPEreIITRNIRLTfEGETRD---ITQYQYEGWPDHNIPDHTQPFRQLLHS
...|| |..| || .||||. |. | ||| |.. |..|| .| .|| . |||. . |... |||. .. . . .. .
tmtreveearlkcykywPer...evPm.......rvGGysvvlldydikePe..ygvralrli.dletrearvvkqldllswPdkvlaPtavglirfvld
ITNRqNQIIPSSDRNVPIIVHCSAGVGRTGTFCTAVIMMKKLD
. .. .. ... |..||...|.||.|.. . ......|
vkqh.ielardasevGPlvvhddvGiGrsGillatlvlvsrle
|
|||||||||
subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 96-330 | 1.6e-32 | 107.6 | In-house | 7-219 (267) | alignment | ||
Range on Protein: 96-330
Range on HMM: 7-219/267.0
KIKEEFRLLEESVGPSET-SEGDKKHNTSKNRYTNILPVNHTRVQLKKIQDKegsdYINANYIDGAYPK-QFICTQGPLPNTIADFWRMVWENRCRIIVM
.|..|| |... | | | ..| .||. . || ..||| |.. .. |||| |..| . | .|| ||.|| |||.||. .. .... .||.
eiekefelikkisdtsstisqsiaeknqernrlddnlpyddtrvilrtkeee....yinasyvegyktknafivtqdplkntitdfltvihdqkvpvivl
LSRESENcRIKcdRYWPEQIGgeQFSIYgngNEVFGTYSVElvevIQDPEREIITRNIRLTFEGeTRDITQYQYEGWpdhNIPDHTQPFRQLLHSITNRq
| . .. |. ..|| ..| | | ... .|.| .. . .||| .... | ....| | |. | || .|. . | | .
ltkvftd.nir..lfwPPkmg..qakky...qdltvehsle....keendyqiitlelkfknes.ahnvtlyyykkw...nintnnkpylkplfgilak.
NQIipsSDRNVPIIVHCSAGVGRTGTFCTAVIMMKKL
||. . | |..|.||.||||.||| .. .....
nql...engnrPlvvacsdGvGrsGtflvidsqlera
|
|||||||||
0046845 | (Phosphotyrosine protein) phosphatases II | 97-475 | 3.5e-83 | 274.6 | In-house | 2-277 (284) | alignment | ||
Range on Protein: 97-475
Range on HMM: 2-277/284.0
IKEEFRLLEESVGPS--ETSEGDKKHNTSKNRYTNILPVNHTRVQLKKIQDK-EGSDYINANYIDG------AYPKQFICTQGPLPNTIADFWRMVWENR
..|||. | . . ..| . ...| |||||..||| .|.|| || .... |.||||||.|.|| ..|.||.||||||||..||||||||..
leeefeellsltvklllslsvallpenlsknRykdilpydhsRVklksldgdledsdYinAsyvdgydldltyikkkfIatqgPlpntvedFwrmvweqn
CRIIVMLSRESENCRIKCDRYWPEQiGGEQFSiygngnevfGTYSVELVEVIQdpEREIITRNIRLTF---EGETRDITQYQYEGWPDHNIPDHTQPFRQ
.|.|||| .. || |.||..|||. |. . | ..|.|... . . ...|...||. .||.| .|...| .||||..|...... .
vrvIVmltelvengrekcaqYwple.gevlty.........gdftvtllseev..kddytvrtleltnlgytgesrtvthfhytswpdhgvppspedlle
LLHSITNRQNQiipsSDRNVPIIVHCSAGVGRTGTFCTAVIMMKKLDHYfkqldatpidqvvdpfthlpiteyqsdnldlkglgyhfkssiynsnginnn
.|. . . ... .... ||.|||||||||||||... .... |..
flrlvrellen....lpgggpivVHCsaGvgRtGtfialdllleqleke...................................................
nnnnlnnnnninnnsngsnntpqtepnneeddddaaesdlkyaimdkyNSRIDFNLFSIVLKLREQRPGMVQQLEQYLFCYKTILDEIYHR
. . ......| .||||||||||.||||.|.|...|. ....
................................................glllgvdvleavkrlreqRpgmvqtleqyrfvyealleylklk
|
|||||||||
0045098 | (Phosphotyrosine protein) phosphatases II | 97-335 | 3.7e-69 | 228.5 | In-house | 9-238 (278) | alignment | ||
Range on Protein: 97-335
Range on HMM: 9-238/278.0
IKEEFRLLEESVGPSETSEGDKKHNTSKNRYTNILPVNHTRVQlkkiqdkegsDYINANYIDGAyPKQFICTQGPLPNTIADFWRMVWENRCRIIVMLSR
.. || | ||| ... . | .||||..|||..|.|| |||||.|||| ||.||.||||||.|.||||||.||.....|||| .
lllefefllllgipseitpalylgnldknRykdilpydhsrVk..........dYINAsyidgy.pkkfIatqgPlpstvadfwrmlwelgitvivmlte
ESENCRIKCDRYWPEqiggEQFSIYgngnevfGTYSVELVEVIQDPEREIITRNIRLT----FEGETRDITQYQYEGWPDHNIPDHT--QPFRQLLHSIT
. |. |.||..|||| ... .| | ..|.|... . .. ..| ... . ..|.| .|...| .||||..|... ..| .|| |
lvelgrekcaqywpe....ggslty.......gdftvtllseevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefir
NRQNQIIPS-------SDRNVPIIVHCSAGVGRTGTFCTAVIMMKKLDHYFK
........ |.. |..||||||||||||.. | .|.. |.. .
ealkllaslllsslllldsggpvlVHCsaGvgRtGtlvaaylmlelleggvd
|
|||||||||
subfamily_PTPN23_pd | Subfamily PTPN23 | 97-477 | 4e-58 | 191.5 | In-house | 17-285 (288) | alignment | ||
Range on Protein: 97-477
Range on HMM: 17-285/288.0
IKEEFRLLEESVG--PSETSEGDKKHNTSKNRYTNILPVNHTRVQLKKIQDkegsDYINANYIDGAYPK--QFICTQGPLPNTIADFWRMVWENRCRIIV
....|..||.. ..| | ...|||...||| .|.||.|.. .| ||||| .. . | .||.||.||..|..|||.||.|.. ..||
ldkkfkeleqkqdkearkrsiaiaklyseknrsrdilPyDhnRvklrgskD....DYinAsfvkdlspgcPdfiatqaPlqstlnDFWlmvyeqkssviV
MLSRESENCRIKCDRYWPEQIGGEQfsIYGNgnevfgtYSVELVEVIQDPerEIITRNIRLTFEG--ETRDITQYQYEGWPDHNIPDHTQPFRQLLHSIT
|| ..| . |.||||||. | . .|. .|| | .| . . . . |...|.... ...... |.. ||.. .|. . . |.|. .
mllskeelgkpkvdrYwPedkgetv..kfgd.......lsvtlksvrete..thvervlkletldadavksvshlqltsWpelGvPasPetllqfldeve
NRQNQIIPSSDRnvPIIVHCSAGVGRTGTFCTAVIMMKKLdHYFKQLDatpidqvvdpfthlpiteyqsdnldlkglgyhfkssiynsnginnnnnnnln
. .. |. |..|||||||||||.|. . ...| . . |
sayeavqrkskt..PlvvhCsaGvgRtgvfalvyaavrel.ekgngll....................................................
nnnninnnsngsnntpqtepnneeddddaaesdlkyaimdkynsridfNLFSIVLKLREQRPGMVQQLEQYLFCYKTILDEIYHRLN
.. .| .||||| |||. ||. |.|. .| .. . |.
................................................diiqvvsrlreqRrfmvqekeqlkfsyeavleaarrvld
|
|||||||||
subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 97-329 | 1.2e-54 | 180.3 | In-house | 21-236 (315) | alignment | ||
Range on Protein: 97-329
Range on HMM: 21-236/315.0
IKEEFRLLEESvGPSETSEGDKKHNTSKNRYTNILPVNHTRVQLKKIQDKEGSDYINANYIDGAYP-KQFICTQGPLPNTIADFWRMVWENRCRIIVMLS
. |||. | . .... . .. | .|||| ||||....||.|. |.|. |||||| || . | .|..||||. .. ||||||.... |||..
fseefhdlpdP.diyrqrvaretinfkknryknilPldsarvkleviddsPdsdyinasyiksvdddkayiasqgPlkasvddfwrmvlqekvttivmvt
RESENCRIKCDRYWPEQIGGeqfSIygngneVFGTYSVELVEViqDPEREIITRNIRLTFEGETRDITQYQYEGWPDHNIPDHTQPFRQLLHSITNRqnq
.|. .||| .|||.. . |. ||...|||... .. . ..|.. . |.| .||.|...|||. .. .| . .|.. .
kkqegdkikcrqywPdrkad...sv......efGsikvellsl..eadtdgvarklvtrkseesrtvtqfqftewPdkGvdkqtssllklikevkad...
iipSSDRNVPIIVHCSAGVGRTGTFCTAVIMMKK
.. ...||||||||||| .... ....
...ngkkefsllvhcsaGvGrtGvvisidevvaq
|
|||||||||
subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 97-324 | 2.7e-50 | 166.2 | In-house | 28-238 (297) | alignment | ||
Range on Protein: 97-324
Range on HMM: 28-238/297.0
IKEEFRLLEESVGPSETsEGDKKHNTSKNRYTNILPVNHTRVQLKKIQDKEGSDYINANYIDGAYPkQFICTQGPLPNTIADFWRMVWENRCRIIVMLSR
.|||. | |. ..| .|| | .|.||.||||.. ||.|. ..|. |||.|| .. | ..|.|| | ..|.||||.||.... .||||.
fseeflclpeaniqpqt.vaekkvnfeksRYkniLPydssRvkLaivnddpdsDyvnasfvkgnkh.rlittqmPmkatvadfWamvldeqvstivmlnd
ESENCRiKCDRYWPEQiggeqfsiygnGNEVFGTYSVELVEVIQdpEREIITRNIRLTFEG--ETRDITQYQYEGWPDHNIPDHTQpFRQLLHSITNRQN
..|. . || |||... | ||. ||.| | . . | |.. .| . .| . |||. |||.... . . ..||. |.. ..
dnerdk.kcaryWsdk...........gvttfGdvsvvllsvse..reGfikrelevtkgkakarrvvkqyqfveWPdkaverkds.assllklisevrk
QIIPSSDRnvPIIVHCSAGVGRTGTFCTAV
. .. |..|||.||||||| ..|
dfsqnaeg..PllvhclaGvGrtgvlltid
|
|||||||||
subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 97-329 | 2e-46 | 153.6 | In-house | 25-247 (325) | alignment | ||
Range on Protein: 97-329
Range on HMM: 25-247/325.0
IKEEFRLLEeSVGPSETSEGDKKHNTSKNRYTNILPVNHTRVQLKKIQDKEGSDYINANYIDGAYPK-QFICTQGPLPNTIADFWRMVWENRCRIIVMLS
. || || |... | .| .|||. |.......|| |. .|. ||||||.|. | |. .| ||..|| |.||.| . || ..|.|
fahefgllp.sddgiakkvamkpenkaknrfknvvaldksrvvletkkddpssdyinasylrddkkkdvflaaqaPltatindlWrlvldWrcsvvvvln
rESENCRIKCDRYWPEQIGGeqfsiygngNEVFGTYSVELVEVIQDPEREIITRNIRLTFEGETRDITQYQYEGWPDHNIPDHTQPFRQLLHSITNRQNQ
| .. .| |||...| ||. |.|. . . . ... . .|||| . |.|. .|.| . . . .|. . . ...
.eldlgkdrcavywpkemgk.........sktfGglevklrtieeisdyvhrvldvkqvkkGetrsvkqfqlqswddmGvqkrpatlisilqlvkavser
IIPSSDRNVPIIVHCSAGVGRTGTFCTAVIMMKK
. . ||.|||||||||||.| . ...|
vtantkastpilvhcsaGvGrtGvfislysalak
|
|||||||||
subfamily_Cele-PTP-13_pd | Subfamily Cele-PTP-13 | 97-346 | 2.8e-39 | 129.4 | In-house | 13-240 (281) | alignment | ||
Range on Protein: 97-346
Range on HMM: 13-240/281.0
IKEEFRLLEESVgPSE-TSEGDKKHNTSKNRYTNILPVNHTRVQLKK-IQDKEGSDYINANYIDGAYPK-QFICTQGPLPNTIADFWRMVWENRCRIIVM
.|.|| | ||. . .. | ||||.|| .. .||||| . .|. .||| |||| . | .| |||| .| ||||||.|.. |||
fkqefsnlpgdp.psdlctvfnqpvnnkknrylnipcldisrvqlkvkmpnknstdyihanyirspflkrgyiltqgpkketradfwrmiwqenttaivm
LSRESENCRIKCDRYWPEQIggeqfsiygNGNEVFGTYSVELVEVIQdpEREIITRNIRLTFEGETRDITQYQYEGWPDHNIPDHTQPFRQLLHSITNRq
| . | | || |.| . | .||. . .. ..| . |..||||| ||.. .. ||| ..|. .. . ..|. | |
lcqfletnrekcaeyfprna.........hcclqfdklsvsyedstv..nkslvttrlnlsyegetrlithwlwkewpdwqvpessevmlkilrkirar.
nqiipssdrNVPIIVHCSAGVGRTGTFCTAVIMMKKLDHYFKQLDatpIDQVV
| ..||||||||.||. . | .. . .| | | |.|
.........stppvihcsagvgrsgtlmaveialqsihshftlpd...ikqiv
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 97-291 | 7.1e-31 | 102.0 | In-house | 7-192 (319) | alignment | ||
Range on Protein: 97-291
Range on HMM: 7-192/319.0
IKEEFRLLEESVGPSEtseGDKKHNTSKNRYTNILPVNHTRVQLKKIQDKEGSDYINANYIDGA--YPKQFICTQGPLPNTIADFWRMVWENRCRIIVML
. |||| | . .. |.|. |..|. .||| |..| |.. . |..|.|. | | ..|..| .| .. .||||.|||.. |.|| |
vaeefrdlPqliarad...evPvtskdksrvinvvPlPetrvvlqrigdddkdeyldasyvrGyddapnsyiaaqvsledsssdfwrtvweqqsrvivql
SRESENCRIKCDRYWPEQIGGEQFSIYGNgnevfgtYSVELVEVIQDPEREIITRNIRLTFEGETRDITQYQYeGWPDHNIPDHTQPFRQLLHSITN
. ||. .| .|.| . .... | ||. . | | . . . | | .. . |.|..| | | |.. ..| . ... .| . .
tdlselGikvcaeylPtketldntslyGd.......ilvtlkgrevkdryaistlllkrvdkeesrelthywy.kwleaevPaeeaaliamllevrs
|
|||||||||
subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 98-339 | 1.4e-61 | 203.0 | In-house | 18-244 (281) | alignment | ||
Range on Protein: 98-339
Range on HMM: 18-244/281.0
KEEFRLLEEsVGPSETSEGDK-KHNTSKNRYTNILPVNHTRVQLKKIQDKEGSDYINANYIDG-AYPKQFICTQGPLPNTIADFWRMVWENRCRIIVMLS
.||.. |.. .| ..|.. | ..|. ||||.|| ..|||.... .... .||||||...| .|..| ||||.|.....||.||||.. ..|||.
ieeyeklaa.igvdntataskadenvlknrYsnivaYDatrvkvtpneenkntDYinanfvpgykgekeyiatqgPvPaslvafWqmvweqkvsaivmvt
RESENCRIKCDRYWPEQIGgeqfsiygngNEVFGTYSVELVEviQDPEREIITRNIRL-TFEGETRDITQYQYEGWPDHNIPDHTQPFRQLLHSITNRQN
|| |. ..|| ||||.. . .|.. |. .. . ... |.|...| . .||||...| .| |||| .|. |. . . . ... ..
reieagklkChrYWPddns..........elkygdvtvksta..eeekatyierkfkleresgetreveqlaytaWPdhGvPattkellefrkevlklte
qiipsSDRNVPIIVHCSAGVGRTGTFCTAVIMMKKLDHYFKQLDA
.....|...|||||||||||. . ..|.... ..||
.....kktkaplvihCsaGvGrtGtyialDrlvkaveaeleeldv
|
|||||||||
subfamily_PTPN13_pd | Subfamily PTPN13 | 98-329 | 4e-53 | 175.4 | In-house | 14-228 (273) | alignment | ||
Range on Protein: 98-329
Range on HMM: 14-228/273.0
KEEFRLLEESVGPSETSEGDKKHNTSKNRYTNILPVNHTRVQLKkiqdKEGSdYINANYIDG---AYPKQFICTQGPLPNTIADFWRMVWENRCRIIVML
.|||. |.| ....| ||.|..|||| |.||...|||.|. .||. ||||..| ..| .|||||.|..|||.|||| ....|.|.
aeefkelrelkpldtcevgkkkenkdknryrnvlPydetrvklg....degg.yinaslikvpvgkdeyeyiacqGPlPetvkdfwqmvweqkaeviamv
SRESENCRIKCDRYWPEQIGgEQFsiygngnEVFGTYSVELVEVIQDPEREIITRNIRLTFEGETRDITQYQYEGWPDHNIPDHTQPFRQLLHSITNRQN
. | |. ..||.|||||. . .. | . . |||..| . . . . ... . ||.|.... .. ||||..| ..... |.. . . |.
tlekekgkvkchrywPeskn.kkl.......kvsnrlevellkvqkldgfvvralavkdsesgesrevahlnfvkwPdhgvPssaaellqfvaevrrlqt
qiipssdRNVPIIVHCSAGVGRTGTFCTAVIMMKK
. ||.||||||.||.||. | ...
.......dagPivvhcsaGiGrsGtlitidvvlgl
|
|||||||||
subfamily_Sponge-PTP4_pd | Subfamily Sponge-PTP4 | 98-160 | 1.4e-10 | 35.2 | In-house | 16-77 (244) | alignment | ||
Range on Protein: 98-160
Range on HMM: 16-77/244.0
KEEFRLLEESVGPSETSEGDKKHNTSKNRYTNILPVNHTRVQLKKiQDKEGSDYINANYIDGA
|||| | . . .. |..|||| ||||...||| | ||||||||||||.|.
keefvglsdhtreflqtnavlsanatknryinilpfdetrvilss.skkegsdyinanyiqgs
|
|||||||||
subfamily_Urchin-PTP-4_pd | Subfamily Urchin-PTP-4 | 99-320 | 9.9e-37 | 121.2 | In-house | 24-186 (392) | alignment | ||
Range on Protein: 99-320
Range on HMM: 24-186/392.0
EEFRLLEESVGpSETSEGDKKHNTSKNRYTNILPVNHTRVQLKKIQDKEGSDYINANYIDGAYP-KQFICTQGPLPNTIADFWRMVWENRCRIIVMLSRE
|||. | . .... . |. | |||| |||| . .||.|. |.| |||.|| ||.. | .|..||| . .. ||||||.... |.|...
eefhdlpgpdi.ypqtvaqkeinlkknryknilpydsarvkleviddipdsdylnasyipsfdnekayiasqgpnaaslddfwrmvfqenvttiamvtkl
SENCrikcdrywpeqiggeqfsiygngnevfgtysvelveviqdpereiitrnirltfE-GETRDITQYQYEGWPDHNIPDHTQPFRQLLHSITNRQNQI
| ..| ..|... |||...| || . .... . |
kegd......................................................kgddartvaqfhftewPdkdvpkhtssllkfikevkadfGqy
ipssdrNVPIIVHCSAGVGRTGTF
|.|.||||||||||
......thpliihcsagvgrtgvv
|
|||||||||
subfamily_Sponge-PTP6_pd | Subfamily Sponge-PTP6 | 99-332 | 2.1e-36 | 120.3 | In-house | 24-241 (439) | alignment | ||
Range on Protein: 99-332
Range on HMM: 24-241/439.0
EEFRLLEeSVGPS---ETSEGDKKHNTSKNRYTNILPVNHTRVQLKKIQDKEGSDYINANYIDGAY-PKQFICTQGPLPNTIADFWRMVWENRCRIIVML
|.| .. |. | ..| .... .|||| .. . .|||| |..| | |||||||.| | .| .| |||| .| ||||.|.|... ||||
eifekin.stspdyaciaslaaqeydqtknrykdvgafdhtrvtlqeipgvphshyinanyikGyyddklyiatqgpkkettddfwrlviekktvtivml
SRESENCRikcdrYWPEQiggeQFSIYGNGnEVFGTYSVELVEVIQdpeREIITRNIRLTFEGEtRDITQYQYEGWPDHNIPDHTQPFRQLLHSITNRQN
. | . ||| . . .||. | .|| . . | . | | | | | | . |..| |||.|.| .. ..|..| ..
tnlvesyk.....ywpsd....aevcygdi.avrvdrnielpnyvi...rgfkvfnerdtteke.rtvlqfhyiawpdknvpaqashvldflrainsand
qiipsSDRNVPIIVHCSAGVGRTGTFCTAVIMMKKLDH
.. |..|||||||||||| . | ...|
.....keeygpvvvhcsagvGrtGtiialdialeqlkl
|
|||||||||
subfamily_PTPN3_pd | Subfamily PTPN3 | 101-328 | 6.3e-53 | 174.5 | In-house | 21-233 (280) | alignment | ||
Range on Protein: 101-328
Range on HMM: 21-233/280.0
FRLLEESVGPSETSEGDKKHNTSKNRYTNILPVNHTRVQLKKIQDkegsDYINANYIDGAYPK-----QFICTQGPLPNTIADFWRMVWENRCRIIVMLS
| | ..|. | .| ||||| .||| ..|||.||. . |||||||.. | ..| |||||..| .|||.||||.....||||
feqlyrkkpglaisaarkpenlsknryrdilpydatrvklkeset....dyinanyvnmeipstglvnryiatqGPlaktatdfWqmvweqksslivmlt
RESENCRIKCDRYWPEQIGGEQfsiygngnevFGTYSVELVEViqDPEREIITRNIRLTFEG--ETRDITQYQYEGWPDHNIPDHTQPFRQLLHSITNRQ
|. |.|| .||||. . .|..||.. . | ......|.. |. . | | |.| || ||||..||... | ...... . .
tlverGrvkChqyWPetedele..........ygefsvkceke..detksyvlrelvlkdketkeerkilqlqylaWpdhgvPddsadflefvervrklr
nqiipsSDRNVPIIVHCSAGVGRTGTFCTAVIMMK
| .. |..||||||.|||| . . . .
......sgkeePvvvhCsaGigrtGvlilletala
|
|||||||||
subfamily_PTPN14_pd | Subfamily PTPN14 | 104-332 | 2.5e-51 | 169.5 | In-house | 32-258 (300) | alignment | ||
Range on Protein: 104-332
Range on HMM: 32-258/300.0
LEESVGPSETSEGDKKHNTSKNRYTNILPVNHTRVQLKKIQDKeGSDYINANYID---GAYPKQFICTQGPLPNTIADFWRMVWENRCRIIVMLSRESEN
. . ...| . . |..|||. ..|| ...||.|. ... ..|||| | |. ...| .||||..|. |||.||||. ..|||| .| |.
ipkkredallstaklpenaeknrfkdvlPyednrvelsptken.stgyinassikvsvggkersyivaqgPleltvqdfWqmvWeqgvqlivmlteeeed
CRIKCDRYWPEQIGGEQfsiygngNEVFGTYSVElVEVIQDPeREIITRNIRLTF--EGETRDITQYQYEGWPDHNIPDHTQPFRQLL---HSITNRQNQ
. |. .|.|.. .. . || . | . .| .||. ..| . .| |.. || ||||..|. ..| . | .|. .. |.
gkeksfkyfPkleskkk.......tvefgkfkvt.tkfseds.dsvittglklkhlpskeertvwhlqytDWpdhgvPeDvkgflsyLeevqsvrrktns
IIPSSDRNVPIIVHCSAGVGRTGTFCTAVIMMKKLDH
..| ... |..||||||||||| .. .... |.|
eveskeskPPvlvhCsaGvGrtGvlilsdlliatleh
|
|||||||||
subfamily_Sponge-PTP5_pd | Subfamily Sponge-PTP5 | 106-329 | 6.9e-38 | 125.1 | In-house | 18-225 (283) | alignment | ||
Range on Protein: 106-329
Range on HMM: 18-225/283.0
ESVGPSETSEGDKKHNTSKNRYTNILPVNHTRVQLKKIQDkegsDYINANYID----GAYPKQFICTQGPLPNTIADFWRMVWENRCRIIVMLSRESENC
|| . .. ..| |||. .|.|.. ||.|| ||||| .| |..| .|.|| .|. |||.||.... ||||.. |.
lsvpdldadiasadenkrknrnqeivpadqwrvelksesr....dyinavfipvsksykqdkkyiiaqsPldrtvvdfWkmvfdekitaivmltklqedl
RIKCDRYWPEQiggeqfsiygnGNEVFGTYSVELVEVIQdpEREIITRNIRLTFE---GETRDITQYQYEGWpdhnipD---HTQPFRQLLhsitnRQNQ
|||| .|||.. | | .| . | | . .. | ... | . .| .. ||...| . |. . |.
rikCsqyWPkr...........GsedyGeftvtlrkett..snsfiikelllrvnssakstlllahyqvidW......leygeqaiinslv.....kfnk
IIP--SSDRNVPIIVHCSAGVGRTGTFCTAVIMMKK
.| .. ||.||||.|.|||..|..|. .|.
vislqteskkgPivvhCstgiGrtavfiaasasvkd
|
|||||||||
subfamily_CG7180_pd | Subfamily CG7180 | 108-331 | 1.7e-40 | 133.5 | In-house | 29-251 (296) | alignment | ||
Range on Protein: 108-331
Range on HMM: 29-251/296.0
VGPSETSEGDKKHNTSKNRYTNILPVNHTRVQLKKIQDKEGSDYINANYIDGA-YPKQFICTQGPLPNTIADFWRMVWENRCRIIVMLSRESENCRiKCD
. . | .|.| |||. ...| ...|| |.|.. .| |||||| |.|. .|..| |..| .|. .|||.|... . .|.|... . . ..
leigdCagglrkenreknrdvkvvPyDynRvvLekldGeeksdYinavyvdsflkkkeyivteapkketvdefWrlvydeeisavvvLtktfdfak.myp
RYWPEQIgGEQFSIYG---NGNEVFGTYSVELVEVIQDperEIITRNIRLTFEGETRDITQYQYEGWPD-HNIPDHTQPFRQLLHSITNRQNQIiPSSDR
|||.. ||. .. . . . . . . . . . ||| ....|. |. ...| |. . .|.. . .... . .
sywpnks.keqygeifveiveekqyanlkirtfkltkk...ivalteqekqvkaetRivklfqlteWeledkvPlstnalielrrrvrlwrekv.dedpe
NVPIIVHCSAGVGRTGTFCTAVIMMKKLD
. |..|..| |..|.| .... . . ...
egPvvvvssdGasRsGvylaidanlelve
|
|||||||||
subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 108-327 | 5.8e-36 | 118.6 | In-house | 43-240 (290) | alignment | ||
Range on Protein: 108-327
Range on HMM: 43-240/290.0
VGPSETSEGDKKHNTSKNRYTNILPVNHTRVQLKkiqDKEGSDYINANYIDGAYPkQFICTQGPLPNTIADFWRMVWENRCRIIVMLSRESENCRIKCDR
|.. | . || . |||| .. . ||| || | ||. |||..| . || |||.| .|. |.|||| ... |||| |. . ||..
vqylerkifdkntefkknrykdvvcndktrvilk...dGydGdyvhanyvkGlka.mfiltqGalkdtvidiwrmvlqekvaaivmlceliedGkakceq
YWPEQIGgEQFsiygngneVFGTYSVELVeVIQDPEREIITRNI--RLTFEGETRDITQYQYEGWPDHNIPDHTQPFRQLLHSITNRqnqiipssdrNVP
|.||. | | . || ..| .|.. .|| . . | .| . .. |||. .. | . ..|... . . |
yypekeG.evl........tfGeitvlcs.eeddkdaniikktlsvrdkdsGkehklkhlkikswpdksvalstlallrtlrilrka..........sGp
IIVHCSAGVGRTGTFCTAVIMM
..||||||.|||||| . . .
vvvhcsaGiGrtGtfvaievgl
|
|||||||||
subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 109-330 | 1.8e-41 | 137.0 | In-house | 21-255 (297) | alignment | ||
Range on Protein: 109-330
Range on HMM: 21-255/297.0
GPSETSEGDKKHNTSKNRYTNILPVNHTRVQLKKIQdkEGSDYINANYI---DGAYPKQFICTQGPLPNTIADFWRMVWENRCRIIVMLSRESENCRIKC
. . | .. ||||..|| .. |||.|.. ..|||||.|. | . ..|..|||| .|. |||..|.|. |.|||... |. | ||
rgesfssakrnsslrknryrdilatddtrvkllrvi..terdyinadyvvfpdeeadlkyilaqGplsatvddfwtlvaeqdvrvivmvaklqedGrdkc
DRYWPEQIGGEQFSiygngnevfGTYSVELVEVIQDPEREIITRNIRLTFEGETRDITQYQYEGWPDHNIP---DHTQPFR----------QLLHSITN-
|||. .. . . | . || . | .| ...| . |.| .. |. .|||| .| . . |. .. .. .
apywpsvvqerlka.........gdvvveflsstsdefdrviltelqliyrsesrvvrhvqflswpdhGvpsdledlvrfqaqvcscciavpmmlalvem
-------RQNQIIPSSDRNVPIIVHCSAGVGRTGTFCTAVIMMKKL
. . . ||....|||||||||.| . ....||
ftamvflqleslraemprnayllvhcsaGvGrsGvvvlsdvilakl
|
|||||||||
subfamily_Cele-PTP-17_pd | Subfamily Cele-PTP-17 | 109-193 | 2.4e-10 | 34.5 | In-house | 25-115 (347) | alignment | ||
Range on Protein: 109-193
Range on HMM: 25-115/347.0
GPSETSEGDKKHNTSKNRYTNILPVNHTRVQLKKIQDKEG-----SDYINANYIDG-AYPKQFICTQGPLPNTIADFWRMVWENRCRIIVM
||. . . ... |||| . .. ||| | . | . |||| .| |..| || |||.|. |||.|| . .|
spskftsvewekslsknrskdvklidatrvvlspeksknsraddvetyinashikfdnaskeyiltqyplpdtvrdfwkmvsvtkvtqvvt
|
|||||||||
subfamily_PTPN1_pd | Subfamily PTPN1 | 110-333 | 2.2e-49 | 162.8 | In-house | 21-231 (290) | alignment | ||
Range on Protein: 110-333
Range on HMM: 21-231/290.0
PSETSEGDKKHNTSKNRYTNILPVNHTRVQLKKIQDkegsDYINANYIDGA-YPKQFICTQGPLPNTIADFWRMVWENRCRIIVMLSRESENCRIKCDRY
.|.| ....| ..||| .. | .|.|..|.. . |||||. .. ...| ||||||||.. ||.||||.... .||| . |. .||| .|
dfptreaklpenrnlnryrdvspydhsrikleradn....dyinaslveleeakrsyiltqGPlpntvdhfWqmvWeqkskavvmlnkvvekeqikcaqy
WPEQIGgeqfsiygNGNEVFG--TYSVELVEviQDPEREIITRNIRLTF--EGETRDITQYQYEGWPDHNIPDHTQPFRQLLHSItnRQNQIIpsSDRNV
||.. . . .. ...|.|.. .. ... . | ..|. |||.|... | ||| .|. . | ..|. . |. . |.
wPqgee........ekellledtklkvklis..eerksyytvrllelenlktqetreilhfhyttwpdfgvpespaaflkflfkv..resGsl..ssdvG
PIIVHCSAGVGRTGTFCTAVIMMKKLDHY
| ..|||||.||.|||| . .. .....
pavihcsaGiGrsGtfclvdtclvliekk
|
|||||||||
subfamily_PTPN12_pd | Subfamily PTPN12 | 111-331 | 1.4e-66 | 219.3 | In-house | 30-235 (290) | alignment | ||
Range on Protein: 111-331
Range on HMM: 30-235/290.0
SETSEGDKKHNTSKNRYTNILPVNHTRVQLKKIQDKEGSDYINANYIDGAY-PKQFICTQGPLPNTIADFWRMVWENRCRIIVMLSRESENCRIKCDRYW
.|..|.|..|. |||| .||| ...||.|.||...|||||||||.| |.. ....| .|||||.|. |||||.|| . .|.||. || |. ..||.|||
ysteagekeenvkknrykDilPydksrvelskieeeegsdYinanfikgvegkleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkkCerYW
PEQiggeqfsiyGNGNEVFGTYSVELVEViQDPEREIITRNIRLTFEGETRDITQYQYEGWPDHNIPDHTQPFRQLLHSITNRQNqiipssDRNVPIIVH
||. |. . ||...|.| | . . ... | .......|.| ..|..|. ||||..| ... .|.... ..|. . ..|..||
pee.........geeelefgefevtleee.kavdddflirtLkveaqkesrkvyqfhYtaWPDhgvPssaksllelielvrelqe......sedaPlvvh
CSAGVGRTGTFCTAVIMMKKLD
|||||||||| .. .. . |
CsaGvGrtGtiiaidyvrellk
|
|||||||||
0040439 | (Phosphotyrosine protein) phosphatases II | 113-333 | 1.2e-68 | 226.8 | In-house | 3-209 (249) | alignment | ||
Range on Protein: 113-333
Range on HMM: 3-209/249.0
TSEGDKKHNTSKNRYTNILPVNHTRVQLKKIQDKEGSDYINANYIDGAY-PKQFICTQGPLPNTIADFWRMVWENRCRIIVMLSRESENCRIKCDRYWPE
.|.. .. | .||||..||| .|.||.|. ... ..||||||.|||| | ...||.||||||.|..|||||.||.....||||... |. |.||..|||.
ysvallpenkdknrypdilpydhsrvklsilpglflsdyinAsyidgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqywpl
qiggEQFSIYgngnevfGTYSVELVEVIQdpEREIITRNIRLT--FEGETRDITQYQYEGWPDHNIPDHTQPFRQLLHSITNRQNQIipssDRNVPIIVH
... | |...|.|..|.. . ....|...|| .||.| ....|| .||||..|...... .... . . .... ... |..||
....ggsley.......gdftvtllsvev..kddytvrtleltnlydgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleel....pkggpvlVH
CSAGVGRTGTFCTAVIMMKKLDHY
|||||||||||..| .|. |...
CsaGvgRtGtfiaaylmleqleke
|
|||||||||
subfamily_Cele-PTP-16_pd | Subfamily Cele-PTP-16 | 113-321 | 1.1e-18 | 61.9 | In-house | 39-229 (303) | alignment | ||
Range on Protein: 113-321
Range on HMM: 39-229/303.0
TSEGDKKHNTSKNRYTNILPVNHTRVQLKkiqDkegSDYINANYIDGAYPKQFICTQGPLPNTIADFWRMVWENRCRIIVMLSRESENCRIKCDRYWPEQ
| . .| |||..... ..|..|.| | | || |.|.. |. | || ||. | ||||.|. |.. . ...| .|| .. | .|..
vsknqfvknmdknrfvdvicldhskvkls...d...ssyihasyleldsskkailtqlplshtaadfwqmiieqkvkcvlllltdseydklggdsvfprn
iggEQFSIYGNGNEVFGTYsvELVEVIQDPEREIITrnirLTfEGETR-DITQYQYEGWPDHNIPDHTQPfrQLLHSITNRQNQIIPSSDRNVPIIVhCS
..| . . | . ||. . ... .. .|. . . ..|. || .|| .. | .... | . | . || . .. .
...qdflkfeersirvgef..krvelgdgwvlkvls....vs.ngdyksflhvhhykawphnsipsdgsp..kfvkqiwqlqsvlrkysdstptvym.sl
AGVGRTGTFC
.|.||.|||.
sgcgragtfa
|
|||||||||
subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 116-331 | 8.2e-48 | 157.8 | In-house | 4-203 (250) | alignment | ||
Range on Protein: 116-331
Range on HMM: 4-203/250.0
GDKKHNTSKNRYTNILPVNHTRVQLKKIQDKEGSDYINANYIDGAYP-KQFICTQGPLPNTIADFWRMVWENRCRIIVMLSRESENCRIkCDRYWPEqig
. | .| ||||..|......|| |.| . . |||||| ...| | || |||||..|| ||||||.|. ||||. .|. . . .|||
akkpqnkeknryadiialdssrvvLekekgdkesdyinasflhgyderkafiatqgPlqatiedfWrmvleeksgtivmLtnLkesekt.yhqywPv...
gEQFSIYGNgnevfgtYSVELVEviQDPEREIITRNIRLTFEGETRD--ITQYQYEGWPDHNIPDHTQPFRQLLHSITNRQNQIipssdRNVPIIVHCSA
|. .||. |.| . .. ....|.. |. . .. . . |... ||| .|.... .||. . |.|. | |.||.|||
.ekaekyGd.......vtvslls..keefadytkrklklskakkaderivrqlhfvvWPdkgvPevatavLellkkvqasqqqa.....gnaPvivqCsa
GVGRTGTFCTAVIMMKKLD
||||.|.|.. ....|
GvgrsGafiaidavlerlk
|
|||||||||
0049772 | (Phosphotyrosine protein) phosphatases II | 116-331 | 6.5e-44 | 146.3 | In-house | 41-240 (314) | alignment | ||
Range on Protein: 116-331
Range on HMM: 41-240/314.0
GDKKHNTSKNRYTNILPVNhTRVQLkKIQDKEGSDYINANYIDGAypKQFICTQGPLPNTIADF----------WRMV--WENRCRIIVM----------
.|. | .||||..|||.. .||.| . .. .|||||||.|.|| ..||.|||||..|. || |||| .....|.|||
adlflnrdknryldilpad.nrvil.pglpvsgsdyinasyvdgf..lkfIatqgpleitvvdfreepvlyyngwrmvlrgdlnvrdivmsrdevladel
-----------LSRESENCRIKCDRYWPEQIggeqfsiygngnevfgtysvelvEVIQDPEREiitrnirltfegeTRDITQYQYEGWPDHNIPdHTQPF
| . ..| . . ..... |.. |||. .| . .| . .||.. | .. |
srLdaAlgKtpllildgngneptaadlellk.......................eelydpelf.............erlgikylripvpDgsap.lledf
RQLLHSITNRqnqiipssDRNVPIIVHCSAGVGRTGTFCTAVIMMKKLD
...|. | . |.. |..|||.||.||||||..| ..||.|.
deflefieea........dkggpvlvHCkaGkgRtgtfvvaaylmkllg
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 116-159 | 6.7e-08 | 26.3 | In-house | 42-85 (440) | alignment | ||
Range on Protein: 116-159
Range on HMM: 42-85/440.0
GDKKHNTSKNRYTNILPVNHTRVQLKKIQDKEGSDYINANYIDG
| |||| ||| .|.|| |.... |||||| ||.|
aslpnnkvknryrnilaydhsrvmleevkgvpdsdyinasying
|
|||||||||
0042113 | (Phosphotyrosine protein) phosphatases II | 117-469 | 6.8e-75 | 246.9 | In-house | 5-240 (245) | alignment | ||
Range on Protein: 117-469
Range on HMM: 5-240/245.0
DKKHNTSKNRYTNILPVNHTRVQLKKIQDKEGSDYINANYIDGAY-PKQFICTQGPLPNTIADFWRMVWENRCRIIVMLSRESENCRIKCDRYWPEqigg
...| .||||..||| .||||.|. .. ..||||||.|.|| . ...||.||||||.|..|||||.||.....||||..| |. |.||..|||.
llpenkdknrysdilpydhtrvklspdggdldsdyinasyvdgyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywpl....
EQFSIYGNgnevfgtYSVELVEVIQdpEREIITRNIRLT--FEGETRDITQYQYEGWPDHNIPDHTQPFRQLLHSITNRQNQiipssDRNVPIIVHCSAG
... ||. ..|.|... . . ....|....| ..|.| ...|.| .||||..||... . ..|. . . ... |.| |..||||||
gesltygd.......ftvtllseeh..lddytvrtlevtnlgddesrevihyhylpwpdhgvpdllellldflefvrkalae.....dsngpvlVHCsaG
VGRTGTFCTAVIMMKKLDHyfkqldatpidqvvdpfthlpiteyqsdnldlkglgyhfkssiynsnginnnnnnnlnnnnninnnsngsnntpqtepnne
|||||||..| .|. |..
vgRtGtfiaaylmleqlek.................................................................................
eddddaaesdlkyaimdkynsRIDFNLFSIVLKLREQRPGMVQQLEQYLFCYKTIL
. ...|...| .||.||||.|| ..|| |.|. .|
.....................elgvsleeavkelrsqRpgavqtpsqyrflyeall
|
|||||||||
0037934 | (Phosphotyrosine protein) phosphatases II | 117-469 | 1.7e-68 | 226.1 | In-house | 6-239 (243) | alignment | ||
Range on Protein: 117-469
Range on HMM: 6-239/243.0
DKKHNTSKNRYTNILPVNHTRVQLkkiqdkEGSDYINANYIDGAypKQFICTQGPLPNTIAD----FWRMVWENRCRIIVMLSRESENCRIKCDRYWPeq
.. | |||||..||| .|.|| | |||||||||.|.. ...|.||||||.|..| ||||.||.....|||| .. |. |.||..|||
llpenlsknrysdilpydhsrvkl......egsdyinanliyvt..prliatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqywp..
iggeqfsiygnGNEVFGTYSVELVEVIQDPEreIITRNIRLTF---EGETRDITQYQYEGWPDHNIPDHTQPFRQLLHSITNRQNQIIP--SSDRNVPII
|....|...|.|... . .. .. |...|. ...|| ...|.| .||||..||..... ..|. ... ...... |.. |..
...........gevtygdftvtllseehldd..ytvrtlllenldlddltrlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvl
VHCSAGVGRTGTFCTAVIMMKKL--Dhyfkqldatpidqvvdpfthlpiteyqsdnldlkglgyhfkssiynsnginnnnnnnlnnnnninnnsngsnnt
||||||||||||...| .|...| |
VHCsaGvgRtGtliaaylmllllgvd..........................................................................
pqtepnneeddddaaesdlkyaimdkynsridfnLFSIVLKLREQRPG-MVQQLEQYLFCYKTIL
|...| .||||||| .|| ..|| |.|. .|
..................................leeavkllreqRpgkavqtpsqyrflyeall
|
|||||||||
subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 117-333 | 2.1e-55 | 182.6 | In-house | 16-227 (270) | alignment | ||
Range on Protein: 117-333
Range on HMM: 16-227/270.0
DKKHNTSKNRYTNILPVNHTRVQLKKIQDKEGSDYINANYIDGA--YPKQFICTQGPLPNTIADFWRMVWENRCRIIVMLSRESENCRIKCDRYWPEqig
. ... |||..||| .|||.|....... . ||||||. |. .|..|...||||.|. .||||.||.. . |||.. |. | ||.||||.
eaargkklnRyadiLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpa...
geqfsiYGNGNEVFGTYSVELVEVIQDPEREIITRNIRLTFEGETRDITQYQYEGWPDHNIPDHTQ---PFRQLLHSITNRQNQIIPSSDRNvPIIVHCS
. . . . .. . . . |. |....||. .||.| .. ..|. |||| .| ... .|||. . . ... .. . |..||||
......epkekvkledgkikvlalseekeegyiltrlrleekgeerrlvHfwyntWpdhgvpreedsslstdqllkmlravrrsekeldkae.PllvHcs
AGVGRTGTFCTAVIMMKKLDHY
||||||||. . |... |..
aGvgRtGtlialDiavrlLeet
|
|||||||||
subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 117-333 | 1.9e-54 | 180.1 | In-house | 21-218 (284) | alignment | ||
Range on Protein: 117-333
Range on HMM: 21-218/284.0
DKKHNTSKNRYTNILPVNHTRVQLKKIQDKEGSDYINANYIDGAY-PKQFICTQGPLPNTIADFWRMVWENRCRIIVMLSresencRIKCDRYWPEQIGG
. ..| |||...||. ....|.|.... .|.|||||| .| | ....| |||||.||.||||||.|| .| ||.|. . || .||| .|
nldqnkdknrighilafdknvvklerliGeefsdyinasfitGyqrkdkyiatqGPldntladfWrmiweyncstivllt......kdkcsqywplkivi
EqfsiYGNGNevfgtYSVELVEVIQDpereIITRNIRLTF---EGETRDITQYQYEGWPDHNIPDHTQPFRQLLHSItnrqNQIIPSSDRNVPIIVHCSA
. ..... .|..|| .. . |.|.|. | . |.|.|. . ||||. ||.. .. .|.. . . . . . .|.|||||
k....eerfk.....vkvdsveesee....yvvrdielsedgkekdirkirqfhflgwpdvgvpdypsdlmrlvkkv....rhltskenhranivvhcsa
GVGRTGTFCTAVIMMKKLDHY
||||||.. . ........
gvgrtgvyivldvlldrmkee
|
|||||||||
subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 117-325 | 8.6e-54 | 177.5 | In-house | 39-231 (515) | alignment | ||
Range on Protein: 117-325
Range on HMM: 39-231/515.0
DKKHNTSKNRYTNILPVNHTRVQLKKIQDKEGSDYINANYIDGAYP-KQFICTQGPLPNTIADFWRMVWENRCRIIVMLSRESENCRIKCDRYWPEQIGG
... | .|||| |||| . .||.|. |.|. |||.|| || . | .|..|||.. .. ||||.|.... |.|... .|. .||| .|||.. |
qeeinfkknryknilPydsvrvklevindnPhsdyfnasyipsfdndkayiasqgPnkasvddfWrlvlqenvttiamvtklkegdkikcgkyWPdkpgd
eqfSIygngneVFGTYSVELVEVIQDpeREIITRNIRLTFEGETRDITQYQYEGWPDHNIPDHTQPFRQLLHSITNRQNQIipssdrNVPIIVHCSAGVG
|. ||...|||| . . . | |..... . ..| .||.....|||. .| ||. . .|.. . ..|. . |.|.|||||||
...sv......kfGsikvelvsleac..tggikrkltvlkgddsrtvtqfhfteWPdkGvpkhtssllklikevkadhgqy......thpliihcsaGvG
RTGTFCTAVI
||| ....
rtGvvisids
|
|||||||||
subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 117-329 | 8.4e-36 | 118.3 | In-house | 4-200 (239) | alignment | ||
Range on Protein: 117-329
Range on HMM: 4-200/239.0
DKKHNTSKNRYTNILPVNHTRVQLKKIQDKEGSDYINANYIDG--AYPKQFICTQGPLPNTIADFWRMVWENRCRIIVMLSRESENCRIKCDRYWPEQIg
|. | .||||.||. .|.|| |.|. . ||||||.|. || .|.||| . . |||||.|..| .||||. | . || .|||.
kkrvnkaknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpdst.
geqfSIYGNGNEvfgtySVELVEVIQDpeREIITRNIRLTFEGETRDITQYQYEGWPDHNIPDHTQPFRQLLHSITNrqnQIIPSSdrnVPIIVHCSAGV
| | | .. ||. | | | . . | | . ||.. |||. .|... | . ||. . .| . | ..||||||
....skycnlrv.....tlrktevfad..yiirtfvmsqvgqteeryvyqyhftvwpdkgvpqyatavlglrrkitk...dslpga...rpwvihcsagv
GRTGTFCTAVIMMKK
||||.| |...
grtgaflvidamlrq
|
|||||||||
subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 117-329 | 9.5e-36 | 118.1 | In-house | 3-199 (239) | alignment | ||
Range on Protein: 117-329
Range on HMM: 3-199/239.0
DKKHNTSKNRYTNILPVNHTRVQLKKIQDKEGSDYINANYIDG--AYPKQFICTQGPLPNTIADFWRMVWENRCRIIVMLSRESENCRIKCDRYWPEQIg
|. | .||||.||. .|.|| |.|. . ||||||.|. || .|.||| . . |||||.|..| .||||. | . || .|||.
kkrvnkaknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpdst.
geqfSIYGNGNEvfgtySVELVEVIQDpeREIITRNIRLTFEGETRDITQYQYEGWPDHNIPDHTQPFRQLLHSITNrqnQIIPSSdrnVPIIVHCSAGV
| | | .. ||. | | | . . | | . ||.. |||. .|... | . ||. . .| . | ..||||||
....skycnlrv.....tlrktevfad..yiirtfvmsqvgqteeryvyqyhftvwpdkgvpqyatavlglrrkitk...dslpga...rpwvihcsagv
GRTGTFCTAVIMMKK
||||.| |...
grtgaflvidamlrq
|
|||||||||
subfamily_Cele-PTP-15_pd | Subfamily Cele-PTP-15 | 117-322 | 3.5e-25 | 83.5 | In-house | 31-222 (285) | alignment | ||
Range on Protein: 117-322
Range on HMM: 31-222/285.0
DKKHNTSKNRYTNILPVNHTRVQLKKiQDKegsDYINANYI--DGAYPKQFICTQGPLPNTIADFWRMVWENRCRIIVMLSRESENCRIKCDRYWPEQIG
. | |||... .. ||| ||. .|. ||| |... | .| ||||||.|..|||.|..... ..|| | || |.||..|
ayeanpdlnryadvrcieetrvvlkn.hdr...dyihaswmrmpgkdqstyittqgplpetlsdfwhmiyqekiayvlmlctlfeggvekcalyypeklg
gEQFsiygngneVFGTYSVELVEVIQDPEREIITRNIRLTFE----GETRDITQYQYEGWPDHNIPDHTQPFRQLLHSITNrqnqIIPssdRNVPIIVHC
| || | . | |. .. | .. .. | . . | |||. |. ..|. .| . . . . | .. || |||
.evv........kfgkyeitlteckeeaiagtilnaltvintedasseplymnhvqvpwwpdqlapedarpmielykwvkk....vnp...kekpicvhc
SAGVGRTGTFCT
||||||| ||
sagvgrtatfvg
|
|||||||||
subfamily_PTPN5_RR_pd | Subfamily PTPN5_RR | 118-469 | 3.3e-64 | 211.6 | In-house | 25-265 (274) | alignment | ||
Range on Protein: 118-469
Range on HMM: 25-265/274.0
KKHNTSKNRYTNILPVNHTRVQL-KKIQDKEGSDYINANYIDGA--YPKQFICTQGPLPNTIADFWRMVWENRCRIIVMLSRESENCRIKCDRYWPEQIG
...||||..||| ...|| | .. ...| |.||||||| | | .. ||||||||.||||||........|||| . .|. . || .|.|....
vfgsqtknryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntvadfWrmiyqeevqvivmltklkeaneqkCavyfPdaed
GEQFSIYGNGNevfgtysVELVEVIQDPEREIitRNIRLTFEGETRDITQYQYEGWPDHNIPDHTQPFRQLLHSITNRQNQiipSSDRNVPIIVHCSAGV
| ||. . .. ..... . .. |.. | ..|... | | ||||. ||..... .|.. . . ... .. . |..||||||.
yeiserygdve.......ikvekiverndysv..rklvlkylerersvkhywytdWPdhksPddantlldlvleveesree...enaklapvvvhCsaGi
GRTGTFCTAVIMMKKLDHyfkqldatpidqvvdpfthlpiteyqsdnldlkglgyhfkssiynsnginnnnnnnlnnnnninnnsngsnntpqtepnnee
|||| | .. | ...|..
GrtGcfiaisiavrqlre..................................................................................
ddddaaesdlkyaimdkynsRIDFNLFSIVLKLREQRPGMVQQLEQYLFCYKTIL
.| ....|| .|| .| ||||. ||| . ....
....................eivvdvlkivcnlrldrGGmvqtseqyelihralc
|
|||||||||
subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 118-331 | 1.8e-52 | 173.3 | In-house | 46-240 (315) | alignment | ||
Range on Protein: 118-331
Range on HMM: 46-240/315.0
KKHNTSKNRYTNILPVNHTRVQLKKIQDKEGSDYINANYIDG-AYPKQFICTQGPLPNTIADFWRMVWENRCRIIVMLSRESENCRIKCDRYWPEQigge
| .| |||| ||.. ...|||| .. ...|||.|||.||| ......|..|||..... ||||.|.|. . ||||. |. . |...|||..
kienkqknryiniiaydksrvqlpllendphsdyvnanfidGynkkrryiaaqgpnvasvkdfwrlvfeedigkivmltnlvegekrkaekywpdk....
qfsiygngNEVFGTYSVELVEviQDPEREIITRNIRLTFEGETRDITQYQYEGWPDHNIPDHTQPFRQLLHSITNRQNQIIpssdrnVPIIVHCSAGVGR
. ..| ..| ... .. . |. | . .|. . |.. |..| ||| ..| .| |. .| . ... . .|.|||||||||
........kviyGkitvtrks..eevnteytvrtlsvvfgdnirevvqlhytswpdmgvpkytiplmnlirtvkqhhtnsv......gaivvhcsaGvGr
TGTFCTAVIMMKKLD
||||.| ......
tGtfitldavldqae
|
|||||||||
subfamily_Cele-PTP-18_pd | Subfamily Cele-PTP-18 | 119-330 | 7.7e-31 | 101.9 | In-house | 46-246 (305) | alignment | ||
Range on Protein: 119-330
Range on HMM: 46-246/305.0
KHNTSKNRYTNILPVNHTRVQLkkiQDKEGSDYINANYID-GAYPKQFICTQGPLPNTIADFWRMVWENRCRIIVMLSRESENCRIKCDRYWPEQIgGEQ
.. |||| .. ... ||.| . .|| |||. . ||.||||| || .| |||| | .... | || | || |.. . ...
aqeagknrykdvgcldnnrvkl...egpwpheyihanyvstptnpkrfictqaplektcadfwymclqdkveaifmlcnllekgakkcleyfaskd.kdv
FSIYGNGNEVFGTYSVEL-VEVIQDPEREIITRNirLTFEG---ETRDITQYQYEGWPDHNIPDHTQPFRQLLHSItnRqnqiiPSsdrNVPIIVHCSAG
... .|. . . .. .| . .. |. || ..| .|.| . ||| .| . .||. | || ||.||||||
lefeekgqkisvkfessvtlkfrkdakakvtetv..lviegpgekarkvthyhwidwpdrgvpaadlailelleka..r.....ps...kgpivvhcsag
VGRTGTFCTAVIMMKKL
.||||. ....|
igrtgsvvmleyildql
|
|||||||||
subfamily_Cele-PTP-8_pd | Subfamily Cele-PTP-8 | 119-329 | 7.6e-30 | 98.9 | In-house | 41-230 (288) | alignment | ||
Range on Protein: 119-329
Range on HMM: 41-230/288.0
KHNTSKNRYTNILPVNHTRVQLKkiqdKEGSDYINANYID-GAYPKQFICTQGPLPNTIADFWRMVWENRCRIIVMLSRESENCRIKCDRYWPEQIGgEQ
|....||.|. . |||.|. . ||.|| . . |....||.| || || .|.|. |. . ||||.. | . | . |.| ..| |.
ianptrdryenlprcditrvkls....ddpdfyiaanvvssakykrrlicaqaPlngtieelWkmllesdveyivmlcellekGkeksaeyfPsklG.ek
FSIYGNgnevfgT------YsvelveviQDPEREIITRNIRLTFEGETRD-ITQYQYEGWPDHNIPDHTQPFRQLLHSItnrqnqiipsSDRNVPIIVHC
| . . .| .. . .| . |||.. . . . |.|. .|. ... .||. . . . ||.||.
arigrl......ctvvkkkr........adidklvkvsllriskegeekvivkilhlleWdddgvPenylsplrllevl..........kslqkPivvhs
SAGVGRTGTFCTAVIMMKK
|||||||||. .|...
saGvGrtgtlililiales
|
|||||||||
subfamily_Cele-PTP-1_pd | Subfamily Cele-PTP-1 | 119-331 | 2.4e-23 | 77.7 | In-house | 18-219 (290) | alignment | ||
Range on Protein: 119-331
Range on HMM: 18-219/290.0
KHNtSKNRYTNILpVNHTRVQLKKIQDKEGSDYINANYIDGAYPKQFICTQGPLPNT-------IADFWRMVWENRCRIIVMLSRESENCRI----KCDR
||. ..|... | |..||| || . .||| ||.. . ..| || |. .. | .|| |. . . . .||| .|... | .
khe.mdqRlevpL.veatrvvLkgygkrfnddyiHAnrvtcpnglrliltqsPqekitekrnStiekfwwmakqEkvkqvVmlcefeeksantslfaCak
YWPEQIGGEqFsiygngneVFGTYSVELVEVIQDpeREIITRNIRLTFEGET-RDITQYQYEGWPDHNIPDHTQPFRQLLHSITNRqnqiipssdrNVPI
| ||..|.| |. .|. . ... ...||.. ..|..| .| ....|| . |....|. . .|.. . .. . |.
Yvpesvgee.l........kfkgltvkCkskeke..ddvetRelvvkfddeeeftvtHsllkgWnklnvqedtktllsliqkvkas..........ktpv
IVHCSAGVGRTGTFCTAVIMMKKLD
|||| |. | .. . . . |.
ivHcvdGiSrsAalaaiilgyQkia
|
|||||||||
subfamily_Sponge-PTP-2_pd | Subfamily Sponge-PTP-2 | 119-212 | 2.8e-10 | 33.4 | In-house | 25-87 (169) | alignment | ||
Range on Protein: 119-212
Range on HMM: 25-87/169.0
KHNTSKNRYTNILPVNHTRVQLKKIQDKEGSDYINAnyidgaypkqfictqgplpntiadfwRMVWENRCRIIVMLSRESENcrikcDRYWPEQ
| .||| . | .||||.|... .. ||||||| ||.|| .||.| . . .|||.
tcnetknrpagplapshtrvklqrvmedlgsdyina..........................rmiwetnasvivvlgdtddk.....nnfwpek
|
|||||||||
subfamily_Cele-PTP-4_pd | Subfamily Cele-PTP-4 | 119-222 | 7.4e-08 | 26.1 | In-house | 49-149 (302) | alignment | ||
Range on Protein: 119-222
Range on HMM: 49-149/302.0
KHNTSKNRYTNILPVNHTRVQLKKIQDkegsDYINANYIDGA-YPKQFICTQGPLPNTI---ADFWRMVWENRCRIIVMLSRESENCRiKCDRYWPEQIg
|.|..||. ... .....|.|.. .| .|.|| .. .. | .| | .. ..|||||..... .|.| .| | . . ..|..
kknlkknqsedvpildsnlvkleaepd....syvnaskvevPeltrsiilaQlpkvdsedsveeFWrmvfqekivsvvilvgeeelkk.tlselfpkks.
gEQFSIYG
.... ||
.gdykeyg
|
|||||||||
subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 120-329 | 7.7e-43 | 141.4 | In-house | 2-198 (237) | alignment | ||
Range on Protein: 120-329
Range on HMM: 2-198/237.0
HNTSKNRYTNILPVNHTRVQLKKIQDKegSDYINANYIDG--AYPKQFICTQGPLPNTIADFWRMVWENRCRIIVMLSRESENCRIKCDRYWPEQiggEQ
.| |||| || .|.|| || . ||||||.|..| ||..|..|||| .. |||.|||...| .||||. |. ..|| .|||. .|
enkiknrygnivaydhsrvvlkgagsg..sdyinatylkgfdgtpkkyiaaqgplesscddfwqmvwqekcsvivmltgliegnelkchkywpst...dq
FSIYGNgnevfGTYSVELVEVIQDPEREIITRNIRLTFEgETRDITQYQYEGWPDHNIPDHTQPFRQLLHSITNRQNQIipssDRNVPIIVHCSAGVGRT
. || | |. | . | .. ||| . | | | |||. |||. .|..| . .. . | || . . . | |.|||||||||
paaygv.....ltvslkkkeefsdytvrslllskrltlk.evrlihqyqftswpdrgvpqqtaallrfrkniinrsphv....sesgpwiihcsagvgrt
GTFCTAVIMMKK
| | |...
giflvidamlrq
|
|||||||||
subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 120-211 | 3.4e-26 | 86.8 | In-house | 46-152 (350) | alignment | ||
Range on Protein: 120-211
Range on HMM: 46-152/350.0
HNTSKNRYTNILPVNHTRVQLK--------KIQDKEGSDYINANYIDGAY-----PKQ--FICTQGPLPNTIADFWRMVWENRCRIIVMLSRESENCRIK
. .||||.|||| .|.||.|| | ...|||||||. . . .| ||.|||.|. ||.... .| ..|..|. . |. . |
elfaknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvelnlek
CDRYWPE
|.|||.|
cyrYWqe
|
|||||||||
subfamily_Sponge-PTP2_pd | Subfamily Sponge-PTP2 | 120-212 | 3.5e-10 | 32.9 | In-house | 25-86 (169) | alignment | ||
Range on Protein: 120-212
Range on HMM: 25-86/169.0
HNTSKNRYTNILPVNHTRVQLKKIQDKEGSDYINAnyidgaypkqfictqgplpntiadfwRMVWENRCRIIVMLSRESENcrikcDRYWPEQ
| .||| . | .||||.|... .. ||||||| ||.|| .||.| . . .|||.
cnetknrpagplapshtrvklqrvmedlgsdyina..........................rmiwetnasvivvlGdtddk.....nnfwpek
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 121-332 | 7.1e-66 | 217.3 | Pfam-A | 1-199 (235) | alignment | ||
Range on Protein: 121-332
Range on HMM: 1-199/235.0
NTSKNRYTNILPVNHTRVQLkkiQDKEG-SDYINANYIDGAY-PKQFICTQGPLPNTIADFWRMVWENRCRIIVMLSRESENCRIKCDRYWPeqiggeqf
| .||||..||| ..|||.| ...|| ||||||||..| .|.||.|||||..||.|||||||......|||| .. |. | ||..|||
nkkknRykdilpydktrvkl...kgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwp........
sIYGNGNEVFGTYSVELVEVIQDPEREIITRNIRLTFEGET---RDITQYQYEGWPDHNIPDHTQPFRQLLHSITNRQnqiipsSDRNVPIIVHCSAGVG
.. . .|...|||.| ... | |...|...|. ..| | ..|..|..||||..|...... .|.... ... .... |..||||||||
.eeeeesltygdikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkveksk......eaksgpvvVhCsaGvg
RTGTFCTAVIMMKKLDH
|||||... |....|..
Rtgtfvaldilleqlea
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 121-332 | 7.1e-66 | 217.3 | In-house | 1-199 (235) | alignment | ||
Range on Protein: 121-332
Range on HMM: 1-199/235.0
NTSKNRYTNILPVNHTRVQLkkiQDKEG-SDYINANYIDGAY-PKQFICTQGPLPNTIADFWRMVWENRCRIIVMLSRESENCRIKCDRYWPeqiggeqf
| .||||..||| ..|||.| ...|| ||||||||..| .|.||.|||||..||.|||||||......|||| .. |. | ||..|||
nkkknRykdilpydktrvkl...kgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwp........
sIYGNGNEVFGTYSVELVEVIQDPEREIITRNIRLTFEGET---RDITQYQYEGWPDHNIPDHTQPFRQLLHSITNRQnqiipsSDRNVPIIVHCSAGVG
.. . .|...|||.| ... | |...|...|. ..| | ..|..|..||||..|...... .|.... ... .... |..||||||||
.eeeeesltygdikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkveksk......eaksgpvvVhCsaGvg
RTGTFCTAVIMMKKLDH
|||||... |....|..
Rtgtfvaldilleqlea
|
|||||||||
0041856 | (Phosphotyrosine protein) phosphatases II | 121-475 | 2e-50 | 166.3 | In-house | 1-174 (182) | alignment | ||
Range on Protein: 121-475
Range on HMM: 1-174/182.0
NTSKNRYTNILPVNHTRvqlkkiqdkeGSDYINANYIDGAYPK-QFICTQGPLPNTIADFWRMVWENRCRIIVMLSresencrikCDRYWPeqiggeqfs
| .||||..|||..|.| ..||||||...|..| .||.|||||..|.|||.||..|.....||.|. ...|||
nldknrysdilpydhsr..........dldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlt.........eelywp.........
iygngnevfgtysvelveviqdpereiitrnirltfEGETRDITQYQYEGWPDHNIPDhTQPFRQLLHSITNrqnqiipssdRNVPIIVHCSAGVGRTGT
| ..| ..||.| .||||..|| .. . .... . . .. |..||||||||||||
....................................ellerlgiqylylpwpDhgvpd.ldelldfieevle..........eggpvlVHCsaGvgRtgt
FCTAVIMMKKldhyfkQLDatpidqvvdpfthlpiteyqsdnldlkglgyhfkssiynsnginnnnnnnlnnnnninnnsngsnntpqtepnneedddda
.. | .|.|. ...
lvaaylmkkl......gvs.................................................................................
aesdlkyaimdkynsridfnLFSIVLKLREQRPGMVQQLEQYLFCYKTILDEIYHR
|...| .|..|||||....|| |.. .|......
....................leeavklvrsrRpgmvitpnqyfflqlallellllk
|
|||||||||
subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 121-211 | 7.2e-19 | 62.3 | In-house | 48-155 (349) | alignment | ||
Range on Protein: 121-211
Range on HMM: 48-155/349.0
NTSKNRYTNILPVNHTRVQLKKIQD-KE-------------GSDYINANYIDGA---YPKQFICTQGPLPNTIADFWRMVWENRCRIIVMLSRESENCRI
.|||| .||| .|.||.||| . |||||||. . |..|.|| ||| |. ||.... |. .... |. . |.
lfaknrykdilPyehsrvklkkslksskvikastsesdsgklddyinanylkltrisvekkyiatqaPlPstvddfykvillngvklvlsLnddkelsle
KCDRYWPE
|||.|| |
kcdiywqe
|
|||||||||
subfamily_Cele-PTP-12_pd | Subfamily Cele-PTP-12 | 121-203 | 1.1e-06 | 22.4 | In-house | 34-116 (332) | alignment | ||
Range on Protein: 121-203
Range on HMM: 34-116/332.0
NTSKNRYTNILPVNHTRVQLKKIQDKEgsDYINANYIDGAYPK-QFICTQGPLPN-TIADFWRMVWENRCRIIVMLSRESENCRI
| || . ..|.||.| . |. |. ||...|| | .| .| |. . | ||||| | . .|... |. .
nmdmnriphlycfdhsrvelapqdgkd..dfynaswvdgyskksayifaqapfndhteyvfwrmvserkpsmilvfgdidekqkr
|
|||||||||
subfamily_Cele-PTP-19_pd | Subfamily Cele-PTP-19 | 122-328 | 4.6e-28 | 92.8 | In-house | 51-239 (301) | alignment | ||
Range on Protein: 122-328
Range on HMM: 51-239/301.0
TSKNRYTNIlPVNHTrVQLKKIQDKEGsDYINANYIDG-AYPKQFICTQGPLPNTIADFWRMVWENRCRIIVMLSRESENCRIKCDRYWPEQIGgeqfsi
|.|| .. | . . .. |.| . | ||.|. |..||.|||||.|| ||| |. ||||... |. ||. | | .|.
kdkhryptv.PckPs.tavevivdGkr.vPihanwiptsGhphrfiatqgPlkntsedfwamlvqydvekivmlgqkvekleekceeylpvkis......
ygnGNEVFGTYSVELVEVIQDPEREIITRNIRL---TFEGETRDITQYQYEGWPDHNIPD-HTQPFrQLLhsitnrqnQIIPSSDRnvPIIVHCSAGVGR
. | ....... . . .|. |.... | . .|| .| |||. |.|...| |.. | .|. ... |.. ||.||||||.||
...ekldigrfkikiknkelilnkkiskrtlevedstgkfatrtvthyqysewtdrgvPkshaelf.dlm........elvkksek..PivvhcsaGiGr
TGTFCTAVIMMK
. .| .. .. .
svafigteylar
|
|||||||||
subfamily_Cele-PTP-11_pd | Subfamily Cele-PTP-11 | 123-336 | 4.6e-25 | 83.0 | In-house | 45-242 (312) | alignment | ||
Range on Protein: 123-336
Range on HMM: 45-242/312.0
SKNRYTNILPVNHTRVQLKKiqDKegSDYINANYID-GAYPKQFICTQGPLPNTIADFWRMVWENRCRIIVMLSRESENCRIKCDRYWPEQIGgeqFsIY
||| || . | | |. || ||.. . |..|.|||||| ||.. ||... . |..|. |. || .| . .| | .
dlnrypniqcwdrgrftlag..de..nfyihanfvkictkperfvctqgplentcthfwqlalslgstsiillcgfvedgsekcakyisdivg...f.vd
GNGNEVFGTYSVElVEVIQDPEREIITRNIRLTF--EGETRDITQYQYEGWPDHNIPDHTQPFRQLLHSITNrqnqiipssDrNVPIIVHCSAGVGRTGT
. |. | | .|. | | ... |. . .||. |||| .|| . .|| .. . | . |.| |||||||||||
ledhrvyteycte.ieiggkskdkithrvlkvvvkatgqesklnhyqwaswpdhgmpdscdtalrllsavkk.........d.kkpviahcsagvgrtgt
FCTAVIMMKKLDHYFKQ
.. |. | | ||
laliesmiaalrhprkq
|
|||||||||
0044763 | (Phosphotyrosine protein) phosphatases II | 132-466 | 1.8e-37 | 124.1 | In-house | 1-165 (178) | alignment | ||
Range on Protein: 132-466
Range on HMM: 1-165/178.0
PVNHTRVQLKKIQDKEGSDYINANYIDgayPKQFICTQGPlpntiADFWRMVWENRCRIIVMLSRESENCRIKCDRYWPEQIGgeqfsiygngnevfgty
|. .||| | .... |.||||||..|. | ......| ||......|. .. ||.|. | |. ..|||.||||. |
pldrtrvllsnleglersdyinaseil...pglylgslpp.....addlellkelgithivnlteelelgflkcdpywpeeag.................
svelveviqdpereiitrnirltfegetrdiTQYQYEGWPDHNIPDHTQPFRQLLHSITNRQnqiipsSDRNVPIIVHCSAGVGRTGTFCTAVIMMKKlD
||.. ..|||. || .. |..... | . . .... |..|||||||||.||.. | .|.| .
...............................iqylhipipDhgvpdllehflefvefieeal......dekggpvlVHCsaGvgRsgtlvaaylmkkl.g
hyfkqldatpidqvvdpfthlpiteyqsdnldlkglgyhfkssiynsnginnnnnnnlnnnnninnnsngsnntpqtepnneeddddaaesdlkyaimdk
....................................................................................................
ynsridFNLFSIVLKLREQRPgMVQQLEQYLFCYK
..|.... .||.|| .|. .|. ..|.
......lsleeaielvrerRp.ivpnpgqlrqLye
|
|||||||||
subfamily_Sponge-PTP-4_pd | Subfamily Sponge-PTP-4 | 138-212 | 2.2e-07 | 25.2 | In-house | 10-72 (130) | alignment | ||
Range on Protein: 138-212
Range on HMM: 10-72/130.0
VQlkkiqdkeGSDYINANYIDGA-YPKQFICTQGPLPNTIADFWRMVWENRCRIIVMLSRESENcrikcDRYWPEQ
.| | .||||... .... || || .| |||.|. | ..|.| |. | |||.
lq........gntyinasfvGllgrtaeylltqhpladtsmdfwkmmleryvnvlvvlgsveee.....deywpds
|
|||||||||
0046846 | (Phosphotyrosine protein) phosphatases II | 143-328 | 1.2e-37 | 124.6 | In-house | 6-134 (176) | alignment | ||
Range on Protein: 143-328
Range on HMM: 6-134/176.0
IQDKEGSDYINANYIDGAYpkqFICTQGPLPNTIADFWRMVWENRCRIIVMLSRESENCRIKCDRYWPEqigGEQ--Fsiygngnevfgtysvelveviq
. . ...||||||.|.|.. .|.||||||.|.|||..|..|......|.| | | |.||..|||| |. .
lgldldldyinanlilgsr...piatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpe...leklgi......................
dpereiitrnirltfegetrditQYQYEGWPDHNIPDHtQPFRQLLHSITNRQNQiipssdrNVPIIVHCSAGVGRTGTFCTAVIMMK
||.. .||||..||. . . .|| | ..... . |..||||||.|||||.. | ....
.......................qylhlpwpDhgvpdl.elllellefirealke.......ggpvlVHCsaGigRtgtlvaayllel
|
|||||||||
0043147 | (Phosphotyrosine protein) phosphatases II | 147-331 | 2.5e-37 | 123.6 | In-house | 3-128 (172) | alignment | ||
Range on Protein: 147-331
Range on HMM: 3-128/172.0
EGSDYINANYIDGAYP-KQFICTQGPLPNTIADFWRMVWENRCRIIVMLSREsencrikcdrywpeqiggeqfsiygngnevfgtysvelveviqdpere
||||||||.|.|. | ..||.|||||.||.||||||..|. ...||.| ..
egsdyinasyldlyyipdrfiatqgplrntladfwrmlkelgithivnltel................................................
iitrniRLTFEGETRDITQYQYEGWPDHNIPdHTQPFRQLLHSITNRQnqiipSSDRNVPIIVHCSAGVGRTGTFCTAVIMMKKLD
.. |...| . ||.| .||||. | ... ....|. | ... ... |..||||||||||||.. | .|...|.
......lydpellerlgiqylylpwpDhgvp.llellleflefidell.....alspggpvlVHCsaGvgRtgtlvaaylmllgls
|
|||||||||
0051429 | (Phosphotyrosine protein) phosphatases II | 148-491 | 3.9e-49 | 163.0 | In-house | 3-244 (272) | alignment | ||
Range on Protein: 148-491
Range on HMM: 3-244/272.0
GSDYINANYIDGAYP----KQFICTQGPLPNTIADFWRMvWENRCRIIVMLSRESENCRIKCDRYWpEQIGGEQFSIYGNGNEVFGTYSVELVEVIQDPE
|.||||....| . . .....||||.|.|||||. .|.... ||.| .|.| | |||||| ..| ...|.... . . . . .
lsgyiNardvggygrvvkpgrlyrsggplpltaadfwrl.kelgiktivdLrseeErgrlkcdryw.pgirylhlpilddsaptilygalrvtllseell
REIITRNIRLT---FEGETRDITQYQYEGWPDHNIPDHTqpFRQLLHSITNrqnqiipssdrNVPIIVHCSAGVGRTGTFCTAVIMMKKldhyfkqldat
.| |...|| ||.| .....| .||||..|... ...||. . . . |..||||||..||||.. .....
ldyilrellltlllsagearevmhlhytdwpdhgvpqea..llellellld...........ggpvlvHCsaGkdRTGtvvallllllg...........
pidqvvdpfthlpiteyqsdnldlkglgyhfkssiynsnginnnnnnnlnnnnninnnsngsnntpqtepnneeddddaaesdlkyaimdkynsridFN-
..
.................................................................................................vsl
-------------LFSIVLKLREQRPGMVQQLEQYLFCYKTILDEIYHRLNCKLGFSLPHVNNIN
|. .| .||.||||.|| |||||.|. .|. .. |... . | ... |.
etivddYlltnlyleeaveelraqrpgavqteeqylflyeallellrsllsvraeyllaaldaid
|
|||||||||
0036282 | (Phosphotyrosine protein) phosphatases II | 148-331 | 3e-39 | 129.8 | In-house | 1-132 (174) | alignment | ||
Range on Protein: 148-331
Range on HMM: 1-132/174.0
GSDYINANYIDGAYP-KQFICTQGPLPntiadFWRMVWENRCRIIVMLSRESENCRIKCDRYWPEqiggeqfsiygngnevfgtysvelveviqdperei
|||||||...|. | . .|..||||. ||.|..|......||| .| |. . || .||||
gsdyinaspldlsyitprliagqgpla.....fwemlkelgittvvmlleekelglykcinywpe...................................
itrnirlTFEGETRDITQYQYEGWPDHNIPDHTQpFRQLLHSITNRQNQiipssDRNVPIIVHCSAGVGRTGTFCTAVIMMKKLD
. | ..| . ||.| .||||. || .. ..... . . ... |.. |..||||||||||||.. | .|.. |
.......lredlerlgiqylylpwpDhgvpdlsi.llefvkfveealse.....dpggpvlVHCsaGvgRtGtlvaaylmlrgll
|
|||||||||
0051082 | (Phosphotyrosine protein) phosphatases II | 148-331 | 5.9e-31 | 102.5 | In-house | 2-120 (151) | alignment | ||
Range on Protein: 148-331
Range on HMM: 2-120/151.0
GSDYINANYIDGAypkqFICTQGPLPntiaDFWRMVWENRCRIIVMLSRESENCriKCDRYWPEQIggeqfsiygngnevfgtysvelveviqdpereii
|||||..|..| .....|||. ||.....|. .. ||.| | |. .| .|.||.
lsdyinfsyvtgg....lyrsggpla....dflellkelgiktivnlrseeerg..ycpeylpelg..................................
trnirltfegetRDITQYQYEGWPDHNIPDHTQPFRQLLHSITNrqnqiipssDRNVPIIVHCSAGVGRTGTFCTAVIMMKKLD
..........|||...|.... ....|. . . ..| |..||||||.|||||.. ...|. ...
............ievlhipildwpdpglplsfdavleflellld.........kkngpvlvHCsaGkgRTGtlvalylmllgvs
|
|||||||||
0049260 | (Phosphotyrosine protein) phosphatases II | 161-331 | 1e-34 | 114.8 | In-house | 7-117 (152) | alignment | ||
Range on Protein: 161-331
Range on HMM: 7-117/152.0
YPKQFICTQGPLPNTIADFWRMVWENRCRIIVMLSRESENCRIKCDRYWpeqiggeqfsiygngnevfgtysvelveviqdpereiitrnirltfegetr
.|..||.||||.|||.||||||..|. ...|||| ...|. ..||..|.
mpfefiatqgpgpntladfwrmlkelgittivmltellelgklkceqyi...................................................
ditQYQYEGWPDHNIPDHTQPFRQLLHSITNRqnqiipSSDRNVPIIVHCSAGVGRTGTFCTAVIMMKKLD
||.. ||||. ||..| ...||. | . |.. |..||||||||||||.. | .|.....
...qylhlpwpDhgvpdlsqlllflllfiekl......aldkggpvlVHCsaGvgRtgtlvaaylmllgvs
|
|||||||||
subfamily_Anemone-PTP-3_pd | Subfamily Anemone-PTP-3 | 163-325 | 5.9e-19 | 63.0 | In-house | 5-157 (199) | alignment | ||
Range on Protein: 163-325
Range on HMM: 5-157/199.0
KQFICTQGPLPNTIADFWRMVWENRCRIIVMLSRESENCRIKCDRYWPEQIGgeqfsiygnGNEVFGTYSVELVEVIQDPEREIITRN--IRLTFEGETR
...|.|| || .|.||||.|||| |||. . | ||| | .|. || . |. | . | ||
rryiatqhplretmadfwqmvwetgsghivmvnddqknkeadypfywpttes.........gtgkygslsvttktittkpdytitaliltnnttappstr
DITQYQYEGWPDHNIPDHTQpFRQLlhSITNRQNQIIPSSDRNVPIIVHCSAGVGRTGTFCTAVI
.|..||. | .. |. . | . .. |. ... |.||||| | | || | . |
eishyqftswkekttpnval.fvgf..vvasrevskkyeqekdapvivhcsdgqgftgvfvaldi
|
|||||||||
subfamily_Nvec-PTP-3_pd | Subfamily Nvec-PTP-3 | 163-325 | 5.9e-19 | 63.0 | In-house | 4-156 (198) | alignment | ||
Range on Protein: 163-325
Range on HMM: 4-156/198.0
KQFICTQGPLPNTIADFWRMVWENRCRIIVMLSRESENCRIKCDRYWPEQIGgeqfsiygnGNEVFGTYSVELVEVIQDPEREIITRN--IRLTFEGETR
...|.|| || .|.||||.|||| |||. . | ||| | .|. || . |. | . | ||
rryiatqhplretladfwqmvwetgsghivmvnddqknkeadypfywpttes.........gtgkygslsvttktittkpdytitaliltnnttappstr
DITQYQYEGWPDHNIPDHTQpFRQLlhSITNRQNQIIPSSDRNVPIIVHCSAGVGRTGTFCTAVI
.|..||. | .. |. . | . .. |. ... |.||||| | | || | . |
eishyqftswkekttpnval.fvgf..vvasrevskkyeqekdapvivhcsdgqgftgvfvaldi
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 164-213 | 1.9e-07 | 24.8 | In-house | 237-283 (440) | alignment | ||
Range on Protein: 164-213
Range on HMM: 237-283/440.0
QFICTQGPLPNTIADFWRMVWENRCRIIVMLSRESENcriKCDRYWPEQI
||.|| || |. ||||.| . | |.|| . .. | ||| .
afiatqmpldstvldfwrlvhdyristiimlnqlndk...tcsiywpvnt
|
|||||||||
subfamily_Sponge-PTP4_pd | Subfamily Sponge-PTP4 | 164-212 | 8.6e-06 | 19.5 | In-house | 138-181 (244) | alignment | ||
Range on Protein: 164-212
Range on HMM: 138-181/244.0
QFICTQGPLPNTIADFWRMVWENRCRIIVMLSRESENcrikcDRYWPEQ
..| || || .| |||.|. | ..|.| |. | |||.
eyiltqhpladtsmdfwkmmlerhvnvlvvlgsveee.....deywpds
|
|||||||||
subfamily_Cele-PTP-9_pd | Subfamily Cele-PTP-9 | 165-332 | 1.6e-18 | 61.7 | In-house | 39-177 (255) | alignment | ||
Range on Protein: 165-332
Range on HMM: 39-177/255.0
FictqgplpnTIADFWRMVWENRCRIIVMLSRESENCRIKCDRYWPEQIGGEQfsIYGNGNeVFGTYsvelveVIQDPEreIITRNIRLTFE--GETRDI
. |.. |.... .. .|||. |. . ||..|.| . . . .. . | | | ..|. . |..| .|. .|...
l.........tvdkfyqtivqtktevvvmlcdfaeegvekcssyfplekdekl..kladvn.vtttk......ssadvv..lrtleitstlgekkkthtv
TQYQYEGWPDHNIPDHTQPFRQLLHSITNrqnqiipsSdRnvPIIVHCSAGVGRTGTFCTAVIMMKKLDH
. |.|.||...| |. .. ...|. ... | . ...||||.|.||. .| | .. .|. .
khysykGWieknaPelareilnilkvvrd........s.k..svvvhCstGiGrsaafvlaelvyqkmir
|
|||||||||
subfamily_Cele-PTP-7_pd | Subfamily Cele-PTP-7 | 170-321 | 2.6e-11 | 37.5 | In-house | 98-239 (302) | alignment | ||
Range on Protein: 170-321
Range on HMM: 98-239/302.0
GPLPNTIADFWRMVWENRCRIIVMLSRESENCRIKCDRYWPEQIGGE-QFSIYGNGNEVFGTYSVELVEVIQDPEREIITRNIRLTFeGETRDITQYQYE
| .|. .| .. . . |.| |. |. || |. ...||| .| | | |. . . . .| . . . . ..
vpkkstlekhwalieqynvaivvqlcsfvedeekkcaeyysdkvggelkfgrytvktvsvktdleeftdkksfklytveiknekkkk.kvkktvdilafs
GWPDHNIPDHTQPFRQLLHSITnrqnqiipSSDRNVpiIVHCSAGVGRTGTFC
.|||| |..... ..|. | .|| .||||||||||||.
awpdhGapkeaytaldilkfce........sykknv..lvhcsaGvGrtGtlv
|
|||||||||
subfamily_hpo-7_pd | Subfamily hpo-7 | 172-330 | 2e-15 | 51.4 | In-house | 43-181 (263) | alignment | ||
Range on Protein: 172-330
Range on HMM: 43-181/263.0
LPNTIADFWRMVWENRCRIIVMLSRESENCRIKCDRYWPEQIGGEQfsIYGNGNeVFGTYSVElveviqdpEREIITRNIRLTFE--GETRDITQYQYEG
| .||. |.... .. .|||. |. . ||..|.| . . | .. | | | | ... . . |... |.. .|.....|.| |
lvqtidkfyqtivqtktevvvmLcDfneegvekcssyfPlekdekq..klanvn.vcttkvqs........dvllktlellstlgeKkkthtvkhysykg
WPDHNIPDHTQPFRQLLHSITNrqnqiipsSdRnvPIIVHCSAGVGRTGTFCTAVIMMKKL
|...| | .. ...|. .| | . ...||||.|.||. | | .. .|.
Wiekndpelareilnilkvarn........s.k..slvvhcstGiGrsaafsvaElvyqkm
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 235-327 | 5.8e-11 | 36.4 | In-house | 66-151 (440) | alignment | ||
Range on Protein: 235-327
Range on HMM: 66-151/440.0
LVEVIQDPEREIITRNirLTFEGETRDITQYQYEGWPDHNIPDHTQPFRQLLHSITNRQNQIipssdRNVPIIVHCSAGVGRTGTFCTAVIMM
| || |. . | |.| . ||.|.||||. .| . | .... . . |.. | |..||||||.|||| . ..
leevkgvpdsdyinas..yingiesrtlkqyhyqgwpdkgvpkfagpvlkmiqdvnesqeka.....gngpllvhcsagagrtgviiavdsil
|
|||||||||
0048179 | (Phosphotyrosine protein) phosphatases II | 248-328 | 5.5e-18 | 60.5 | In-house | 35-108 (144) | alignment | ||
Range on Protein: 248-328
Range on HMM: 35-108/144.0
TRNIRLTFEGETRDITQYQYEGWPDHNIPDHTQPFRQLLHSITNRQNqiipssdRNVPIIVHCSAGVGRTGTFCTAVIMMK
. . | ..| ..||.. .||||..||... ....|. | . .. .. |..||||||||||||...| .|.|
nlteeyepefleregiqylhlpwpDhgvpdllellleflefieeale.......eggpvlVHCsaGvgRtgtlvaaylmkk
|
|||||||||
0038934 | (Phosphotyrosine protein) phosphatases II | 248-328 | 1.1e-09 | 33.7 | In-house | 58-140 (194) | alignment | ||
Range on Protein: 248-328
Range on HMM: 58-140/194.0
TRNIRLTFEGETRDITQYQYEGWPDHNIP--D-HTQPFRQLLHSITNRQNQIIPSSDRNvPIIVHCSAGVGRTGTFCTAVIMMK
. |.|| .. . | . .. | ...| | .| | ..|... . .... . . . ||| ||.|||||.. | ....
glvidltnteryYdpeefekagieylklpfpddgtvPsleillrfldlvdeflnedpgg.vvaVHCkaGlgRtGtlvaaYLiyr
|
|||||||||
0048076 | (Phosphotyrosine protein) phosphatases II | 250-328 | 3.3e-19 | 64.4 | In-house | 35-106 (145) | alignment | ||
Range on Protein: 250-328
Range on HMM: 35-106/145.0
NIRLTFEGETRDITQYQYEGWPDHNIPDHTQPFRQLLHSITNRQNQiipssdrNVPIIVHCSAGVGRTGTFCTAVIMMK
|. ..|...| ..||.| .||||..|| .. ....|. | . ... . |..||||||||||||.. | .|..
nltselellerlgiqylylpwpDhgvpdllellleflefieealke.......ggpvlVHCsaGvgRtgtlvaaylmll
|
|||||||||
subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 260-328 | 4.7e-09 | 30.0 | In-house | 218-290 (349) | alignment | ||
Range on Protein: 260-328
Range on HMM: 218-290/349.0
RDITQYQYEGWPDHNIPDHTQPFRQLL----HSITNRQNQIIPSSDRNVPIIVHCSAGVGRTGTFCTAVIMMK
. | |. |.| . . . | | . | . . .|. ...|||||| ||||...| ...
yellqlqvknwldlslllnPisilqalevkndliddlfarlyldtdqlstllvhcsaGcGrtGvlvtldllls
|
|||||||||
PTPc_DSPc_SM00012 | 262-339 | 6e-23 | 76.4 | In-house | 2-75 (105) | alignment | |||
Range on Protein: 262-339
Range on HMM: 2-75/105.0
ITQYQYEGWPDHNIPDHTQPFRQLLHSITNRQNQIIPssdrNVPIIVHCSAGVGRTGTFCTAVIMMKKLDHYFKQLDA
...|.| |||||..|...... .||... . .|.. . |..|||||||||||||... |....|.. |..|
vkhyhytgwpdhgvPeesdsilellravkknknkses....skpvvVhCsaGvgRtgtfvaldillqqleketkevdi
|
|||||||||
subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 262-331 | 1.5e-11 | 38.7 | In-house | 217-290 (350) | alignment | ||
Range on Protein: 262-331
Range on HMM: 217-290/350.0
ITQYQYEGWPDHNIPDHTQPFRQLLH----SITNRQNQIIPSSDRNVPIIVHCSAGVGRTGTFCTAVIMMKKLD
. | |.. |.| .. . . . | | | . . ..| ||.||||||||||||..| ......
vyqlqvknWkDlslllnPesilqalevkndliddlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsdfe
|
|||||||||
PTPc_motif_SM00404 | 268-328 | 2.5e-08 | 28.9 | In-house | 45-105 (140) | alignment | |||
Range on Protein: 268-328
Range on HMM: 45-105/140.0
EGWPDHNIPDHTQPFRQLLHSITNRQNQIIPSSDRNVPIIVHCSAGVGRTGTFCTAVIMMK
.| .|| . . .|.. . . . | . ... ..||| ||| |..|...| .|..
sgfqilqiplddnekdklskyldkvldfienaekkggkvlVHCqaGvSRSatliiaYlmry
|
|||||||||
subfamily_PTEN_pd | Subfamily PTEN | 273-330 | 4e-09 | 31.7 | In-house | 85-141 (184) | alignment | ||
Range on Protein: 273-330
Range on HMM: 85-141/184.0
HNIPDHTQPFRQLLHSITNRQNQIIPSSDRNVpIIVHCSAGVGRTGTFCTAVIMMKKL
.. ||. | .||..| . .. . ....|| ..||| || ||||. .| .. ..|
ypfdDhnppplelleeivediekwleedkknv.vvvHCkaGkGRtGvlivayllksll
|
|||||||||
DSPc | Dual specificity phosphatase, catalytic domain | 274-329 | 1.6e-07 | 26.3 | Pfam-A | 49-99 (133) | alignment | ||
Range on Protein: 274-329
Range on HMM: 49-99/133.0
NipDHTQPFRQLLHSITNRQNQIipsSDRNVPIIVHCSAGVGRTGTFCTAVIMMKK
.... . . | .... ... ... ..||| ||. |..|...| .|..|
d..etetkiskeleeavefieka...eqkgkkvlVHCqaGisRSatliiaYlmktk
|
|||||||||
DSPc | Dual specificity phosphatase, catalytic domain | 274-329 | 1.6e-07 | 26.3 | In-house | 49-99 (133) | alignment | ||
Range on Protein: 274-329
Range on HMM: 49-99/133.0
NipDHTQPFRQLLHSITNRQNQIipsSDRNVPIIVHCSAGVGRTGTFCTAVIMMKK
.... . . | .... ... ... ..||| ||. |..|...| .|..|
d..etetkiskeleeavefieka...eqkgkkvlVHCqaGisRSatliiaYlmktk
|
|||||||||
PTEN_1 | 275-330 | 2.2e-08 | 29.2 | In-house | 102-157 (196) | alignment | |||
Range on Protein: 275-330
Range on HMM: 102-157/196.0
IPDHTQPFRQLLHSITNRQNQIIPSSDRNVPIIVHCSAGVGRTGTFCTAVIMMKKL
|.||. | . |. | .. . . | ... ..||| ||.||.|| . | | |.
ieDhgapslselfdicksfiewllsdpngnvVlVHCkaGlgRsGtvvaayLmykgk
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 301-338 | 8.3e-07 | 23.0 | In-house | 245-282 (319) | alignment | ||
Range on Protein: 301-338
Range on HMM: 245-282/319.0
DRNVPIIVHCSAGVGRTGTFCTAVIMMKKLDHYFKQLD
... |..|||| ||||||. .. | ...|.. . .|
esqGPlvvhcsdGvGrtGlviasdiairsleeskrsvd
|
|||||||||
0043336 | (Phosphotyrosine protein) phosphatases II | 426-469 | 2.8e-08 | 29.0 | In-house | 231-274 (278) | alignment | ||
Range on Protein: 426-469
Range on HMM: 231-274/278.0
YAIMDKYNSRIDFNLFSIVLKLREQRPGMVQQLEQYLFCYKTIL
| ... .... ..|...| .|||||||.|| ..|| |.|. .|
yllleqlekeggvdleeavkelreqRpgavqtpsqyrflyeall
|
|||||||||
0040439 | (Phosphotyrosine protein) phosphatases II | 426-470 | 1.3e-07 | 27.0 | In-house | 200-244 (249) | alignment | ||
Range on Protein: 426-470
Range on HMM: 200-244/249.0
YAIMDKYNSRIDFNLFSIVLKLREQRPGMVQQLEQYLFCYKTILD
| ... .. . ...|...| .||.||||.|| .||| |.|. .|.
ylmleqlekelgvdleeavkllrsqRpgavqnpeqyrflyealle
|
|||||||||
PTPc_DSPc_SM00012 | 427-469 | 6.9e-10 | 34.4 | In-house | 61-104 (105) | alignment | |||
Range on Protein: 427-469
Range on HMM: 61-104/105.0
AIMDKYNSR-IDFNLFSIVLKLREQRPGMVQQLEQYLFCYKTIL
.... ... ...| || .||.|||||||..|||||.|. .|
illqqleketkevdifqivkelrkqRpgmvqteeqylflyrall
|
|||||||||
subfamily_PTPRA_pd | Subfamily PTPRA | 427-477 | 1.8e-09 | 32.0 | In-house | 250-301 (330) | alignment | ||
Range on Protein: 427-477
Range on HMM: 250-301/330.0
AIMDKYNSRIDFNLFSIVLKLREQRPGMVQQLEQYLFCYKTILDE-IYHRLN
|.... .. ..| .| .|| ||| ||| .||| |.||..|. .| .
avlervkaerkvdvfefvkrlrlqrpqmvqtdeqyefiykvlleyylygdte
|
|||||||||
subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 427-472 | 3.5e-07 | 24.8 | In-house | 246-291 (319) | alignment | ||
Range on Protein: 427-472
Range on HMM: 246-291/319.0
AIMDKYNSRIDFNLFSIVLKLREQRPGMVQQLEQYLFCYKTILDEI
...|. . ... .| ||.||. .||.| || |.| ..|.|
vlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysalleeh
|
|||||||||
subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 427-471 | 3.9e-07 | 24.5 | In-house | 197-241 (250) | alignment | ||
Range on Protein: 427-471
Range on HMM: 197-241/250.0
AIMDKYNSRIDFNLFSIVLKLREQRPGMVQQLEQYLFCYKTILDE
|.... . ..| .. .||..||..|. |||| |.|. ||
avlerlkkekvvdvfkvikvlrkdrphavesleqyvfvyeiilka
|
|||||||||
subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 427-473 | 4.2e-07 | 24.8 | In-house | 210-256 (284) | alignment | ||
Range on Protein: 427-473
Range on HMM: 210-256/284.0
AIMDKYNSRIDFNLFSIVLKLREQRPGMVQQLEQYLFCYKTILDEIY
...|. . ... .| .||.||. .||.| || |.| ..|.|
vlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysalleehl
|
|||||||||
subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 427-470 | 8.6e-07 | 23.5 | In-house | 245-288 (298) | alignment | ||
Range on Protein: 427-470
Range on HMM: 245-288/298.0
AIMDKYNSRIDFNLFSIVLKLREQRPGMVQQLEQYLFCYKTILD
..... . .| .| ||..|||.|| ||| |.|. .|.
svlervkkeqvvDvfqvvkvlRkkrpgavqteeqYvfiyeavle
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 428-469 | 3.4e-10 | 35.1 | Pfam-A | 193-234 (235) | alignment | ||
Range on Protein: 428-469
Range on HMM: 193-234/235.0
IMDKYNSRIDFNLFSIVLKLREQRPGMVQQLEQYLFCYKTIL
.... ... ......|| .||.|||||||.|||| |.||.||
lleqleaeeevdvlqivkelRkqRpgmvqsleqYiflykail
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 428-469 | 3.4e-10 | 35.1 | In-house | 193-234 (235) | alignment | ||
Range on Protein: 428-469
Range on HMM: 193-234/235.0
IMDKYNSRIDFNLFSIVLKLREQRPGMVQQLEQYLFCYKTIL
.... ... ......|| .||.|||||||.|||| |.||.||
lleqleaeeevdvlqivkelRkqRpgmvqsleqYiflykail
|
|||||||||
subfamily_PTPN13_pd | Subfamily PTPN13 | 428-470 | 3.1e-09 | 31.5 | In-house | 225-267 (273) | alignment | ||
Range on Protein: 428-470
Range on HMM: 225-267/273.0
IMDKYNSRIDFNLFSIVLKLREQRPGMVQQLEQYLFCYKTILD
... . .|.. || |||||| |.|| .||.|.||.||.
vlglierdkefdvkeivrklreqrqgvvqtkdqyifvykaile
|
|||||||||
subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 428-471 | 1.6e-08 | 29.0 | In-house | 239-282 (319) | alignment | ||
Range on Protein: 428-471
Range on HMM: 239-282/319.0
IMDKYNSRIDFNLFSIVLKLREQRPGMVQQLEQYLFCYKTILDE
.... . ..||.| .|| ||. |||. ||| |.|...|.
mlervkeegvlDvfstvsrlRtqRnimvqrpeqYkfiyeallea
|
|||||||||
subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 429-472 | 1.5e-07 | 25.9 | In-house | 240-283 (305) | alignment | ||
Range on Protein: 429-472
Range on HMM: 240-283/305.0
MDKYNSRIDFNLFSIVLKLREQRPGMVQQLEQYLFCYKTILDEI
... . ..| .. .||..|..|||.|.|| |.. . ..|
lerlkkEevvdvfevlkqlRskrmkmvqtldqYvflhdaldeli
|
|||||||||
subfamily_CG7180_pd | Subfamily CG7180 | 429-475 | 6.3e-07 | 23.3 | In-house | 247-293 (296) | alignment | ||
Range on Protein: 429-475
Range on HMM: 247-293/296.0
MDKYNSRIDFNLFSIVLKLREQRPGMVQQLEQYLFCYKTILDEIYHR
... . ...| | .||..||..|.. |.| ..| ..|. . .
lelvekeeevdvFeavktlrrsRpqLvenveeYkyiYdvlleavlcn
|
|||||||||
subfamily_PTPN12_pd | Subfamily PTPN12 | 430-477 | 5.9e-10 | 33.5 | In-house | 235-282 (290) | alignment | ||
Range on Protein: 430-477
Range on HMM: 235-282/290.0
DKYNSRIDFNLFSIVLKLREQRPGMVQQLEQYLFCYKTILDEIYHRLN
. . ....|..||.||.||. .|| ||| . ||.... . ..|.
kaekipeeldvfdlvlelrkqraalvqtkeqyelvykavaelvqkele
|
|||||||||
subfamily_PTPRD_pd | Subfamily PTPRD | 431-472 | 1.2e-09 | 32.4 | In-house | 240-281 (564) | alignment | ||
Range on Protein: 431-472
Range on HMM: 240-281/564.0
KYNSRIDFNLFSIVLKLREQRPGMVQQLEQYLFCYKTILDEI
. .. . .....| .||.||. |||. ||| |....||. .
rikeektvDiyqyvkalrkqRnamVqteeQYiFiheaileal
|
|||||||||
subfamily_PTPN9_pd | Subfamily PTPN9 | 431-470 | 3e-06 | 21.5 | In-house | 249-288 (297) | alignment | ||
Range on Protein: 431-470
Range on HMM: 249-288/297.0
KYNSRIDFNLFSIVLKLREQRPGMVQQLEQYLFCYKTILD
. .. ... | .||.|| ..| ||| |||...|.
rleevgtvdvvetvkllrtqrafsiqtpeqyefcylavle
|
|||||||||
subfamily_PTPRB_pd | Subfamily PTPRB | 432-473 | 2.7e-06 | 21.6 | In-house | 245-286 (293) | alignment | ||
Range on Protein: 432-473
Range on HMM: 245-286/293.0
YNSRIDFNLFSIVLKLREQRPGMVQQLEQYLFCYKTILDEIY
... ..|.|| .|||.| .|| .||.| ....|| .
ieeedyvdifgivaelReeRnllvqtekqYifihqcvldllr
|
|||||||||
subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 433-473 | 1.6e-08 | 29.0 | In-house | 240-280 (288) | alignment | ||
Range on Protein: 433-473
Range on HMM: 240-280/288.0
NSRIDFNLFSIVLKLREQRPGMVQQLEQYLFCYKTILDEIY
.. .....| |||.||. .||.|.|| |.|...|. |.
eeedyiDvagtvaklRkqRallvqtlkqYefiyevllslie
|
|||||||||
subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 433-476 | 2.4e-06 | 21.6 | In-house | 238-281 (315) | alignment | ||
Range on Protein: 433-476
Range on HMM: 238-281/315.0
NSRIDFNLFSIVLKLREQRPGMVQQLEQYLFCYKTILDEIYHRL
. . ..| .| .||..|| .|| |.| | | ..|.....|
krtrsvdvfnfvknlrakrpylvqteeeyafiydavledllwrn
|
|||||||||
subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 433-471 | 4.4e-06 | 21.0 | In-house | 251-287 (325) | alignment | ||
Range on Protein: 433-471
Range on HMM: 251-287/325.0
NSRIDfnLFSIVLKLREQRPGMVQQLEQYLFCYKTILDE
.||.| .| | |||..|| ||. .|| ..|... .
esrvd..ifgfvkklrkdrpsmvetvdqyiliyealvea
|
|||||||||
subfamily_Ptp69D_pd | Subfamily Ptp69D | 434-472 | 1.2e-08 | 29.4 | In-house | 248-286 (307) | alignment | ||
Range on Protein: 434-472
Range on HMM: 248-286/307.0
SRIDFNLFSIVLKLREQRPGMVQQLEQYLFCYKTILDEI
..| .| .||.||. .||.|||| |.|. .|| .
aedkvdifetvkdLrsqRnllvqsleqYvflyralldys
|
|||||||||
subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 436-469 | 2.1e-07 | 25.0 | In-house | 308-341 (350) | alignment | ||
Range on Protein: 436-469
Range on HMM: 308-341/350.0
IDFNLFSIVLKLREQRPGMVQQLEQYLFCYKTIL
. .. ||..||.|| |||.|.|..|.|...|
trDlisiivnelrkqrismvqnldqfifiYeall
|
|||||||||
subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 436-472 | 1.4e-06 | 22.5 | In-house | 223-259 (267) | alignment | ||
Range on Protein: 436-472
Range on HMM: 223-259/267.0
IDFNLFSIVLKLREQRPGMVQQLEQYLFCYKTILDEI
..| ..|.|.||.|.|. .|.|....... .
gvsdifdflrkirsqriglvdtkeryiyihellaeya
|
|||||||||
subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 436-472 | 1.8e-06 | 22.3 | In-house | 248-284 (297) | alignment | ||
Range on Protein: 436-472
Range on HMM: 248-284/297.0
IDFNLFSIVLKLREQRPGMVQQLEQYLFCYKTILDEI
. ..| .| |||..|| .|| ||| | |...|. .
kevdifglvkklrqerpylvqtkeqykfvyvavleal
|
|||||||||
0045098 | (Phosphotyrosine protein) phosphatases II | 437-472 | 8.7e-07 | 24.1 | In-house | 236-272 (278) | alignment | ||
Range on Protein: 437-472
Range on HMM: 236-272/278.0
DFNLFSIVLKLREQRPG-MVQQLEQYLFCYKTILDEI
..|...| .||.|||| .|| |||| |.|. .|. .
gvdlleavkelrsqRpglavqnleqyrflyefllell
|
|||||||||
subfamily_PTPRG_pd | Subfamily PTPRG | 437-477 | 9.1e-06 | 19.1 | In-house | 252-292 (563) | alignment | ||
Range on Protein: 437-477
Range on HMM: 252-292/563.0
DFNLFSIVLKLREQRPGMVQQLEQYLFCYKTILDEIYHRLN
|.| .. ..| ||. .||. |||.| ....|. | . .
avnvfgflkhiraqRnflvqteEqYiflhdalleaiasket
|
|||||||||
subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 439-473 | 6e-08 | 27.1 | In-house | 247-281 (318) | alignment | ||
Range on Protein: 439-473
Range on HMM: 247-281/318.0
NLFSIVLKLREQRPGMVQQLEQYLFCYKTILDEIY
..| .| .|||||. ||| .|| |.|...|. .
Dvfqtvkqlreqrnlmvqtedqyefiydvlleala
|
|||||||||
subfamily_PTPRK_pd | Subfamily PTPRK | 439-471 | 1.3e-06 | 22.5 | In-house | 244-276 (314) | alignment | ||
Range on Protein: 439-471
Range on HMM: 244-276/314.0
NLFSIVLKLREQRPGMVQQLEQYLFCYKTILDE
..| .| .||.... ||. ||| |.| ||.
dvfnavktlrsrkvnmveteeqykfiydvilea
|
|||||||||
subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 439-475 | 6.1e-06 | 19.6 | In-house | 243-279 (515) | alignment | ||
Range on Protein: 439-475
Range on HMM: 243-279/515.0
NLFSIVLKLREQRPGMVQQLEQYLFCYKTILDEIYHR
..| .| ..|..|| .|| ||| | | ..|.... |
dvfnfvtnirqkrpylvqtqeqyafiygavledllwr
|