Gene Dd5P3 in Dictyostelium discoideum

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family Sac
Subfamily Synaptojanin
Protein sequence
ID Type Fasta BLAST phosphatome Note
DdisP050_AA protein Get Run
DdisP050_AA_201-545 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
Sac_COG5329 45-958 5e-137 449.7 In-house 51-912 (1070) alignment 
Range on Protein: 45-958
Range on HMM: 51-912/1070.0
IDQSLRSERSVYCVLGIFRLVNECYLVVVTESDIAAnfqFQGQPNVIRKIRCTDFISFQT-GRGHISIGGgggggGSGNGESKEDDRPYVQVMNLLNSGH
  .||.|   .| |||.. |  . .| |.|..  .|    . . . | ||.  |||| .   . .. |        . . |... . |  .   ||  | 
gfrslssaheiygvlGlielegslflivitgkskva...qvipgetiykilavdfislnnnkwddeeies.....deasteklrsehpcselkkLlsngs

FYWTppnSSFDITRTYQSQcLEPKSDlPVWERVDKRFYWNKYLQKDFIAYRL------------YDWCFPIIQGFVVSDHLgHIQGKNVVYTLISRRSRF
|| .   . |||| | |.. |. .   ..... |..|.||..| ...| ||              ..  ..|.||. .     ...| .. |||||||  
FYfS...tdfditntLqkr.lkeele.lsvdtadeefmwnsflleelinyrsklsslekqlldnagFlttvIrGFaetvfi.kvkkktiaLtlISRrSsk

RAGTRFVTRGIDDDGNVANFCESEQILSIESYgVLAFLQIRGSVPVFWNQSSPQMsdlkikmsnlskigkiSKKKITIARNTQATTPAFQLHLKEQTKKY
|||||| .||.||||||||| | |||.  ..| . .|.|.|||.|.|| | | ..                 ..|| |.|  .|| .||. | .....||
ragtRflarGvDddGnvanFVETEqIvyssqy.cfsFtQvRGSiPiFWeqesnsl................igpkiqitrsseatqsafdkHFdklfekY

GNIVIVNLLSKlKSGECDLVNAYEEQIRILRSPQVFYNHFDLNEQTKGNRMDPLDSLINYIDNQsISGGGgttggvsekivgYFF-QNSNGQIISKQNGI
| ..|||||.. || |  |  .||.... .  |.... .||.. .|. ...| .  |...| .. .. .|            ||.  ...|..||.|.|.
GdvhivNLlkt.KssEieLseryekhlklsekpkihlteFdfhketsqdgfddvkkLlplieqd.llefg............yfsydvkegkliseQdGV

IRTNCKDCLDRTNIVQSRVS-WVLFESQLRKLGLFRGHDSigsypRVSQTLKTTWADNGDALSIQYAGSGSLKSTLTREGDYGIMGMLADGKKTMTRFYI
.|||| |||||||..|. .| .|| | .      . ..|         | |.. |||||||.| .| |.|.||| .|| |   | | | |  | ..|.||
fRtNClDCLDRTNviQqliskrvlleqfrsikvisaidde.....dflqklneLWadnGDaisqiYTGtgalkssftrkgkrsiagalsDatkSvsRmyi

NNFKDPGRQDVLDLLLGLHKS-MVVNNSNNGNggnggngsghdDNIRKQVQDRVKEYSKKEWRNVFVGTYNVGGVHSSyFDLVQWLRPDGANCpTPDFYV
||| | ..||  |||||  .   .|  . . |           . .  . . . .|... .  ..|..|.|. |. ||  .|...|.. .    .....|
nnfvDkekQdaidllLgklpdqeavelydpin...........eyvnlrlrkseseftaaknvsiftltfnsngesss.tkllklllkvlekk.isklvv

LGLQEVVELTAGQILATDSSIGKQWEDAIERALPKVSPNVKYIK--LQSSQLVGLLMAIYVREDAIHYFREVQIQNVKCGMNGLAGNKGGIGVRLLFSDT
.. ... ..... ||.....  . .|   |. . |.. ..|. |   .|||| .|..   .. |   .  ... .  | |  ||..||| . .. .  ..
gvvglqkqiwlelillssltksefkeeeeenlvrkyenklkkkkleqsssqltalfilfkksadikevvssekaagrktgtgglnankgavkieaesegl

SFTFVTAHFAAGQSNVEDRISDFREIDSTLAFGRQGQFKvsDSDYSFWLGDFNFRIDLPDEEIRRCVYDQQFPKLYNYDQLRKCMEaGRVFNGYREETIA
.|.|| |..|... |...| |. . | . . ...   .|  | .  .. ...|..||...||.|. . ... ..|..||.  . .| . ....  |.|  
vfifvdasaaledenesernskyesitkrvskeipkmik..dhqlilldiainltidydeeevraekekeidrelkkydtkqelte.kvfvekvleptev

FPPTYKYDLNSTQYDTSQKQRSPAWTDRIVWSNKVHHdlrQLYYHRQEILASDHRPVSSYFQLEVTKIDKDKERTLRQELYEQKSSQF-ITTSQSTNNLI
.....|.. . . ........ . .|....  ... .   .| |.  |. .|||.||   ....| . |..|.  |...|. .   .    ...  ..|.
pellekksyeddndtdtedayrklrtrkliqkeekkt...elaysslelkisdhkpvtaevkiavlskdekkklklelslkiayktekpselpeepdels

ntTNQNGKDGANLITKEFEQLTLIKQSASTPNL
   .  .||  .  .  . |   .|..   .  
..sallskdlekisldatkqskvvklvdlddtm
subfamily_FIG4_pd Subfamily FIG4 48-550 5.8e-60 194.2 In-house 63-543 (569) alignment 
Range on Protein: 48-550
Range on HMM: 63-543/569.0
SLRSERSVYCVLGIFRLVNECYLVVVTESDIAANFqfqGQpNVIRKIRCTDFISFQTGRGHisiggggggggsgnGESKEDDRPYVQVM-NLLNSGHFYW
 |. . | | .||. |...  ||..||     |.    |.  .| ||  ...|. ..   .               |.. |.  |.... ..  . .||.
glekkvsayGilGfvrflegyylilvtkrkkvavi...Gg.haiykiedialikitedskk..............sekssdearylklfkdvdltknfyf

TppnSSFDITRTYQSQCLEP---KSDLP-----------VWERVDKRFYWNKYLQKDFIAYRL-YDWCFPIIQGFVVSDHLgHIQGKNVVYTLISRRSRF
.    |.|.||| |.  |..   ...                . ...| ||..| . . .    .||   || |||  ... .. ||..  |||.|||. 
s...ysydltrtlqtnlllsdsnrekekaedrvditieakkldanekfvWnnflleplkdtvktfdWlleiihGfvsqski.svlgksiyvtliarrssk

RAGTRFVTRGIDDDGNVANFCESEQIL------SIESYGVLAFLQIRGSVPVFWNQSSPQMsdlkikmsnlskigkISKKKITIARNTQATTPAfQLHLK
 ||.||. ||.. .|.|||  |.|||.      |..|  . .|.|.|||||..|.|   ..               ..| .|.|..     ..|  ||..
faGarflkrGvnnkGdvaneveteqivheasegsldsdryssfvqlrGsvPlyWsqdaskl...............vtkPpikidvvdPfasaa.alhfd

EQTKKYGN-IVIVNLLSKL--KSGECDLVNAYEEQIRILR-----SPQVFYNHFDLNEQTKGNRMDPLDSLINYIdNQSISGGGGTT-GGVSEKIVgyff
.  ..||. |.|.||. |   .  |  | ...|. |. |      . .. | ..|.. ..| .  . |. | .|  ..|.   |  . .  .|       
dlfqryGspiiilnlvkkkekrkresilleefeaaieylneflPeekklkyiswdmaraskskeenvlevlekya.eksvkktGiflsapdlestk....

qnsngqiisKQNGIIRTNCKDCLDRTNIVQSRVSWVLFESQLRKLGLFRGhDSIGSYPRVSQTLKTTWADNGDALSIQYAGSGSLKSTLTREGDYGIMGM
          |.||.|||| |||||||  |  .. | .  || .||.     ..     | . |.  . | || |..||.||   ..  |          
.........iqeGivrtnCvdcldrtnaaqfvigkvalgyqlkslGiide.sklefdsdvvrlleelyedlGdtlalqygGsqlvntiktyrkiaqwssk

LADGKKTMTRFYINNFKDPGRQDVLDLLLGLHKS
  |  .|..|.| | |.|  .|| ..|.|| .. 
srdiletlkryysnsfvdadkqdainlflGvysp
subfamily_INPP5F_pd Subfamily INPP5F 53-990 0.0 1284.9 In-house 1-930 (951) alignment 
Range on Protein: 53-990
Range on HMM: 1-930/951.0
RSVYCVLGIFRLVNEC--YLVVVTESDIAANFQF---------------------QGQPNVIRKIRCTDFISFQTGRGHISIGGGGGGGGS---------
|.||.|.|...||.|.  .||.|.||.|......                     ........|..||..|......|.|...  .|   .         
rlvygvigkillvseeerkLvivsessilgllpvqkkeskkevvaiervakldlsekdskelekeectgliglielegkiivatiegkskvnnkkwdlid

--------------GNGESKEDDRPYVQVMNLLNSGHFYWTPpnsSFDITRTYQSQCLEPKSDL-PVWervDKRFYWNKYLQKDFIAYRLYD---WCFPI
               | |.|...|.. ....||..|.||...   .||.|.|.|...||.||.  ..|   |.||.|||.|.||.|.||...   ...|.
idssgylqlkeekeqneeeklekrlleelkkllsdgsFYysl...dfDltntlqkrgleeksestddw...derFfWNkfllkdlinyrdkldkefltpv

IQGFVVSDHLGHIqGKNVVYTLISRRSRFRAGTRFVTRGIDDDGNVANFCESEQILSIESYgVLAFLQIRGSVPVFWNQSspqmsdlkikmsnlskiGKI
||||| .... ..  ..|..||||||||.||||||..||||||||||||.|.|.|||.|.| ||.|.||||||||||.||                 ||.
iqGfvetkeisie.klkvsltlisrrSrkragtrfkrrGidddgnvAnfvEtElilsveky.vlsftqirGSvPvfweqs.................gkk

SKKKITIARNTQATTPAFQLHLKEQTKKYGNIVIVNLLSKlKSGECDLVNAYEEQIRILRSPQVFYNHFDLNEQTKGNRMDPLDSLINYIDNQSisgggg
.|.||.|.|....|.|||. |.|||.||||..|||||||. || |..|..||.||...|.|..||...||..|.|.|........||..|.|..      
ykpkikitrseeetqpaFdehfkeqlkkygkvvivnllsq.kssekklskaykeqllkleskdvflikfdfheetsgekfenvsklieliknei......

ttggvseKIVGYFFQNSNGQIISKQNGIIRTNCKDCLDRTNIVQSRVSWVLFESQLRKLGLFRGHDSIGSyPRVSQTLKTTWADNGDALSIQYAGSGSLK
       | ||||........||.|.|..||||.|||||||.||...|....|.||.|||||....|| . ....|.||..|||||||.|.||||. .||
.......kevgyfsydvkekviseqkgvfRtnclDcldrtNvvqqaiskavlelqleklglfepessidd.eellqklkklWadngdaisrqYagtnalk

STLTREGDYGIMGMLADGKKTMTRFYINNFKDPGRQDVLDLLLGLHKSMVVNNSNNGNGGNGGNGSghddnirkqvqdRVKEYSKKEWRNVFVGTYNVGG
..|||.|.....|.|.||.|...|.|.|||||..||.|.||||| .... |....... .......            |.||....|..|.......|..
gdltrkgerklaGvlkdgyksvsryylnnfkdkyrqkvidlllGklpkqevvelidpkkeekeeel............rekeekftetsninllvgsvnv

VHSSYFDLVQWLRPDGANCPTPDFYVLGLQEVVELTAGQILATDSSIGKQWEDAIERALPKVSPNVKYIKLQSSQLVGLLMAIYVREDAIHYFREVQIQN
..||.......|.........||..|||||||||||||.|||.|.|..|.||...|..|.|||...||.||.|.||..||....||||......||....
ngsskkadlskllfpigekfkpDlvvlGLqEvvELtaGsiLaaDyskskfWEklvedlLnkvsreekYlkLrseqlsslLlllfvredkakkvkevegdt

VKCGMNGLAGNKGGIGVRLLFSDTSFTFVTAHFAAGQSNVEDRISDFREIDSTLAFGRQGQfkVSDSDYSFWLGDFNFRIDLPDEEIRRCVYDQQFPKLY
.|.|..|||||||...||. .|.|||.||..|.|||.||||.|.||..||.....|.|...  ..|.|..|||||.|.|||||.||.||...||...||.
kktGfgGlagnkGavavrfeysatsFcfvnsHlaAGasnveeRrsDykeiarsitFsrskr..ikdhDsifWlGDlnyRidlpneevRRelldqeidkLl

NYDQLRKCMEAGRVFNGYREETIAFPPTYKYDLNSTQYDTSQKQRSPAWTDRIVWSNKVHHDLRqlYYHRQEILASDHRPVSSYFQLEVTKIDKDKERTL
.||||.|..|||.||.|..|||..|.|||||||....||||.|.|.|||||||.....|..||.  ||...|||.||||||...|...||..|..|..||
eyDqLtkeieaGevFegfkEetlkFrPtYkyDlgtknYDtsekeRtPaWtDRiiykgevledLe..yysdaeilisDHrPvyaafrakvtvvDekkkltL

RQELYEQKSSQFITTSQSTNNLINTTNQNGKDGANLITKEFEQLTLIKQSASTPNLQKGRSNTTniQYQITSTNQISNTNNNTIQQQQ
...|||.........|.|............|..|....|..|...|..........|.  |..   .. ..|..| .   ..  ....
kkklyeeykeeleeasdsekdellsddlekkeeaesldkivesaelklldldpkraqdssssvs..kllsgsakqvkvvldvdsasvs
subfamily_SAC1_pd Subfamily SAC1 53-548 2e-108 353.9 In-house 5-453 (458) alignment 
Range on Protein: 53-548
Range on HMM: 5-453/458.0
RSVYCVLGIFRLVNECYLVVVTESDIAANFqfQGQpnVIRKIRCTDFISFQTGRGHISiggggggggsgnGESKEDDRPYVQ-VMNLLNSGHFYWTppnS
.... .||| .|.   ||.|.|. . ....  .|.  || ..  .. |....   . .             | |.... |.. . ..|.| .||..    
vkiagilGiikLlsgkylivitkkeevgri..ngk..viyrvadveiipvkknslslt............eeqkkeekeylkllelvlksetfYfs...y

SFDITRTYQSQCL--EPK-SDLPVWERVDKRFYWNKYLQKDF-IAYRLYDWCFPIIQGFVVSDHLgHIQGKNVVYTLISRRSRFRAGTRFVTRGIDDDGN
 .|.|...| .    ... .  ...||.|.||.|||.|..|.    .| ..  |.|.||. . .| ....|.....|||||| ||||||. .||.| .||
tydltnslqrlekvtsaalkerslleradeRffwnkhlledlrkepelesfilPvikGfikikel.slnakeikfilisRRsifRaGtRyfvRGvdkeGn

VANFCESEQILSIEsYGVLAFLQIRGSVPVFWNQsspqMSDLKIKmsnlskigkiskKKITIArNTQATTPAFQLHLKEQTKKYGNIVIVNLLSKlKSGE
|||| |.|||...|   . .|.|.|||.|..|.|    ...||.|             |...  ... .. ||. ||.||...||. |.|||. . |  |
vanfvEtEqiveae.kaltsFvqvRGsiPllWsq....kpnLkyk............Pkvkls.esedsldafkkhldeqielygenvlvnLvdq.kGsE

CDLVNAYEEQIRILRSPQVFYNHFDLNEQTKGNRMDPLDSLINYIDNQsisggggttggvsEKIVGYFFQNSNGQIISKQNGIIRTNCKDCLDRTNIVQS
  | .|||. .|.|..... |. ||  .. . .| | |. ||. ....             .. .|||.......|...|.|..|||| |||||||.|||
kklgeayesvvralnkkkikyvafDFHkeCrkmrwdrlklLidqleke.............lsqegyflkseekkivkeqkgvvRtnCiDcLDRtnvvqs

RVSWVLFESQLRKLGLFRGHDSIGSYPRVSQTLKTTWADNGDALSIQYAGSGSLKSTLTREGDYGIMGMLADGKKTMTRFYINNFKDPGRQDVLDLLLGL
 ..    ..||..||. . . ..   ... .. | .||||.||.|.|||| | ||.  || |    .|.| || ....|.|.|||.|  ||| .||.|| 
llarevLqkqleslgvlateskledsaeletsfknlwadnadavsvqYaGtgAlKtDftRtGkrtllGalrDgvnsvsryyknnfldgerqdsidLflgk

H
 
y
Syja_N SacI homology domain 55-383 3.1e-84 273.8 Pfam-A 1-318 (319) alignment 
Range on Protein: 55-383
Range on HMM: 1-318/319.0
VYCVLGIFRLVNECYLVVVTESDIAANFQfqgQ-PNVIrKIRCTDFISFQTGRGHISIGGGgggggSGNGESKEDDRPYVQVMNLLNSGHFYWTPpnsSF
.|..||..|| .| ||.|.|... .|...   .  ... ||. ..||.... . . |.        . . |.||....  .. .||.||.||.     ..
aygilGlirllsesyllvitkrekvakir...gehpiy.kiksvefiplnseeeessaiee.....ekeeeekeeekllkllkkllssgsfYfSy...dy

DITRTYQSQCLEPK-------SDLPVWERVDKRFYWNKYLQKDFIAYR--LYDWCFPIIQGFVVSDHLGHIQGKNVVYTLISRRSRFRAGTRFVTRGIDD
|.||. |... . .       . || ...||.||.||..|.|..| ..  | .|..|.||||| . ..   ..|.| .|||||||. |||||. .|||||
DltrslqrksekeeeekeeeskslpllkevderFvWNrnllkplielkldlsrwllpliqGfveqrsievkskkkveltLIsRrsvkraGtRylrRGidd

DGNVANFCESEQILS-I-E-SYGVLAFLQIRGSVPVFWNQsSPQMSdlkikmsnlskigkiSKKKITIARNTQATTPAFQLHLKEQTKKYGNIVIVNLLs
|||||||.|.|||.|   | |  |..|.|||||||.||.| ....|                |.||.| |...|...||..|.|...|.||.||.|||| 
dGnvANfvEtEqivsekkeeskrvfSfvqiRGSvPlfWeq.asnls...............lkpkikitrsseasqkafkkHfkklikrYgkivvvnLl.

KLKSGECDLVNAYEEQIRIL-----RSPQVFYNHFDLNEQTKGNRMD
. |..|. | .||||.|. |     .. .. | .||.....||....
ekkgrEkkLseayeelinklnkklkekkklkyiefDfhkeckgkkfe
Syja_N SacI homology domain 55-383 3.1e-84 273.8 In-house 1-318 (319) alignment 
Range on Protein: 55-383
Range on HMM: 1-318/319.0
VYCVLGIFRLVNECYLVVVTESDIAANFQfqgQ-PNVIrKIRCTDFISFQTGRGHISIGGGgggggSGNGESKEDDRPYVQVMNLLNSGHFYWTPpnsSF
.|..||..|| .| ||.|.|... .|...   .  ... ||. ..||.... . . |.        . . |.||....  .. .||.||.||.     ..
aygilGlirllsesyllvitkrekvakir...gehpiy.kiksvefiplnseeeessaiee.....ekeeeekeeekllkllkkllssgsfYfSy...dy

DITRTYQSQCLEPK-------SDLPVWERVDKRFYWNKYLQKDFIAYR--LYDWCFPIIQGFVVSDHLGHIQGKNVVYTLISRRSRFRAGTRFVTRGIDD
|.||. |... . .       . || ...||.||.||..|.|..| ..  | .|..|.||||| . ..   ..|.| .|||||||. |||||. .|||||
DltrslqrksekeeeekeeeskslpllkevderFvWNrnllkplielkldlsrwllpliqGfveqrsievkskkkveltLIsRrsvkraGtRylrRGidd

DGNVANFCESEQILS-I-E-SYGVLAFLQIRGSVPVFWNQsSPQMSdlkikmsnlskigkiSKKKITIARNTQATTPAFQLHLKEQTKKYGNIVIVNLLs
|||||||.|.|||.|   | |  |..|.|||||||.||.| ....|                |.||.| |...|...||..|.|...|.||.||.|||| 
dGnvANfvEtEqivsekkeeskrvfSfvqiRGSvPlfWeq.asnls...............lkpkikitrsseasqkafkkHfkklikrYgkivvvnLl.

KLKSGECDLVNAYEEQIRIL-----RSPQVFYNHFDLNEQTKGNRMD
. |..|. | .||||.|. |     .. .. | .||.....||....
ekkgrEkkLseayeelinklnkklkekkklkyiefDfhkeckgkkfe
subfamily_Synaptojanin_pd Subfamily Synaptojanin 127-860 2.9e-159 522.9 In-house 58-752 (754) alignment 
Range on Protein: 127-860
Range on HMM: 58-752/754.0
EDDRPYVQVMNLLNSGHFYWTPPNS---SFDITRTYQSQCLEPKsdlpvwErvDKRFYWNKYLQKDFIAYRL--YDWCFPIIQGFVVSDHLgHIQGKNVV
.|.  .... .||.||.||..  ..   ..|.... | .  | .      |  |.||.||. |   .  . .   || .... | |    . ..  |.. 
sdedriielkkllasgtfyfsssadsasrldlslsaqrrkqees......e..dnrffWnrslhlhlqrfgvncddWllkvmcGsveirtv.yagakqak

YTLISRRSRFRAGTRFVTRGIDDDGNVANFCESEQILSIESyGVLAFLQIRGSVPVFWNQSSPQmsdlkikmsnlskigkISKKKITIARNTQATTPAFQ
 .|||| |  |||||| .||..|.||||||.| ||.....   |..|.|||||||.||.|   |                . ..|. ..|. .|...||.
aalisrlsceraGtrfnvrGvndeGnvanfveteqvilldd.kvtsfvqirGsvPlfWeqPGlq................vGshkvklsrgfeasaaafd

LHLKEQTKKYGNIVIVNLLSkLKSGECDLVNAYEEQIRILR-SPQVFYNHFDLNEQTKGNRMDPLDSLINYIDNQSISggggtT-GgvsekivgyFFQNS
 ||... ..||..||||||   | ||  | .|.... .    ...| . .||  ...||.... |..|.. . .. ..     . .         || ..
rhleqlkeryGevvivnllG.skegeevlskafkkhlkasehakdvpfvkfdyhqkvkggkkeklekllkkqlklfle.....sas.........fflsk

NGQIISKQNGIIRTNCKDCLDRTNIVQSRVSWVLFESQLRKLGlFRGHDSIgsYPRVSQTLKTTWADNGDALSIQYAGSGSLKSTLTregdygiMGMLAD
.... ..|.|..|.|| ||||||| ||. ..  . |.||  |.   .. |.    |.....|. |  ||| .|  |||.|.|..          .. | |
gkevekeqtGvlrvnClDCldrtnavqtvlglevlekqlealk.lsskesv..vsrfeevfkslWsknGdeiskiyaGtgalegkak.......vsklkd

GKKTMTRFYINNFKDPGRQDVLDLLL-G-LHKSMVVNNSNNGNGGNG-GngsgHDDNIRKQVQDRVKEYSKKEWRNVFVGTYNVGGVHS---SY---FDL
|.....|   ||| |  .|. .|||| |  ... . .....            .  .|.|.. .| .|... .   ..|||.|| | ..          |
garsvartiqnnfldsskqeaidllllgntyveeladkarallkssllr....asakilkelvereqelteakklricvgtwnvnggkqlrsvalknesl

VQWLRPD----GAN-CPTPDFYVLGLQEVVELTAGQILATDSSIGKQWEDAIERALpkvSPNVKYIKLQSSQLVGLLMAIYVREDAIHYFREVQIQNVKC
 .||       ||.     | | .|..|.|.|.|. .. . ..  |.| . ....|   | . ||. | | ||||. . ..|| . . . |.| .. || 
tdwlldlpelsgaedskpadiyaiGfeelvdlnasnlvsasttnrkewaeelqkvl...srdakyvlltseqlvGvclfvfvrpklvpfirdvavstvkt

GMNGLAGNKGGIGVRLLFSDTSFTFVTAHFAAGQSNVEDRISDFREIDSTLAFGRQGqfKVSDSDYSFWLGDFNFRIDLPDEEIRRCVYDQQFPKLYNYD
|..| |||||....|||.  ||. |. .|.|||||.|..|  |. || . .||.     ...  || |||||||.||||. .|....| .... || . |
GlgGaaGnkGavairlllhstslCfiCshlaagqskvkernedyaeiarkiafpmgr..tleshdyvfWlGdfnyridlekdevkelvkkkdydklvend

QLRKCMEAGRVFNGYREETIAFPPTYKYDLNSTQYDTSQKQRSPAWTDRIVWSNK
||.|  ..|.||.|. | .. | |||||||.| .||||.|.| ||||||..| .|
qltkqkkkgkvfkgfaegeltfaPtykydlfsddydtseklrvPaWtdrvlwrrk
Exo_endo_phos Endonuclease/Exonuclease/phosphatase family 596-880 4.6e-32 101.7 Pfam-A 1-249 (249) alignment 
Range on Protein: 596-880
Range on HMM: 1-249/249.0
GTYNVGGVHSSYFD------LVQWLRPDGancptPDfyVLGLQEVVELTAGQILAtdSSIGKQ-------------WEDAieralpkvspnvkyiklqss
.|.||.| .  . .      | ..|.  .     ||  || ||||.|    . ||   . ...               ||                    
ltwNvlgwnarsdrakkldqladllqsed.....pD..vllLQEvdedplsella..tglaselgldgdgksggggggda....................

qlVGLLMAIYVREDAIHYFREVQIQNVKCGMN---GLAGNKGGIGVRLLfsDTSFTFVTAHFAAGQSNVE--DRiSDFREIDSTLAFGRQGqfkvsdsdY
  .|  .|.... .  .. | .   ..|.|     .  ||||...||.   ......|..|...|... .   |  ...|||.  ...|..        .
..gggglallskypldkkirrtfqldgkagiavprlssgnkgdvpvrfr..gktlalvntHltpgnrlrqrder.allaeidkladdsrgs........p

SFWLGDFNFRIDLPDeeirrcvydqqfpklynydqlrkcmeagrvfNGYREETIAFPPTYKYDLNSTQY-------------DTSQKQRSPAWTDRIVWs
 ...||||.|.|.||                               .|.||. . |.|....| .. ..             ||. |.| ||..|.| . 
vilaGDfNsrpdspd...............................kgfresaadflpgdgfddglrallphlllptspgttdtyekareparlDyilv.

NKVHHDLRQLYYHRQEILA-SDH
.. . .|.  .... ..   |||
ssgwpalvvsgasllsdrggSDH