Gene fcpA in Dictyostelium discoideum

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold HAD
Superfamily HAD
Family FCP
Subfamily SCP
Protein sequence
ID Type Fasta BLAST phosphatome Note
DdisP063_AA protein Get Run
DdisP063_AA_136-277 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
BaxI_1 Bax inhibitor 1 like 90-175 4.4e-06 13.3 Pfam-A 14-101 (274) alignment 
Range on Protein: 90-175
Range on HMM: 14-101/274.0
QQQQQYNQHQQQQQQQQQQQQYINKDSSQQNGEIPLMVPMIPRHVGLKTLV--LDLDETLVHSSFKPVHNPDFIVPVEIEGTIHQVYV
.|| .| | ...  . . .||. ...  ||. . .   ..   .|..|| .    | ...| |.|  . |.|   |. . |.|  . .
kqqGgyaqFgtaaaaaagaqqvtkqqylqqaqqtgaeraltiddvviktgitlavlklsavvsyflvlfnvdlaspltlvGaigGlvl
subfamily_SCP_pd Subfamily SCP 137-277 1.1e-80 260.3 In-house 1-141 (142) alignment 
Range on Protein: 137-277
Range on HMM: 1-141/142.0
KTLVLDLDETLVHSSFKPVHNPDFIVPVEIEGTIHQVYVVKRPFVDDFLRAIAEKFEIVVFTASLAKYADPVLDFLDTGRVIHYRLFRESCHNHKGNYVK
|.||.||||||||||||||.|.||.|||||.||.|||||.|||.||.||....|.||.|.||||||||||||.|.||. .|...|||||||..|||||||
kclvidldetlvhssfkpvknadfvvpveidgtvhqvyvlkrphvdeflkrvgelfevvlftaslakyadpvadlldkkkvlrarlfrescvfhkgnyvk

DLSRLGRDLKSTIIVDNSPSSYLFHPENAIPIDSWFDDKDD
||||||||||..|||||||.||.||||||.|..||||||.|
dlsrlgrdlkkviivdnspasyifhpenavpveswfddked
NIF NLI interacting factor-like phosphatase 137-297 1.1e-58 189.6 Pfam-A 1-159 (159) alignment 
Range on Protein: 137-297
Range on HMM: 1-159/159.0
KTLVLDLDETLVHSSFKPVHNPDFIVPveiEgTIHQVYVVKRPFVDDFLRAIAEKFEIVVFTASLAKYADPVLDFLDT-GRVIHYRLFRESCHNHKGNYV
||||||||||||||..|. .. |.  .   | . ....|.|||..|.||. .....|.|.||||  .||.|||| ||. ......||.||||  ..|.||
ktLVLDLDetLvhskekkdlkedgkkv...e.ektkasvkkRPgldeFLkelskayevviftasskeyaepvldkldpkkklfkkrlyresctlrngkyv

KDLSRLGRDLKSTIIVDNSPSSYLFHPENAIPIDSWFDD-KDDRELLDLLPLLDDLIKVEDVR
|||| |||||....|||.|| |....|.|.|||.....| ..|.|||.|||.|..| |..|||
KdLsllgrdlsrvvivDdsprsfelqpdngipiepfygdsdkdtellkllpflealeksddvr
subfamily_DULLARD_pd Subfamily DULLARD 137-277 5.2e-50 161.1 In-house 2-151 (153) alignment 
Range on Protein: 137-277
Range on HMM: 2-151/153.0
KTLVLDLDETLVHS--------SFKPVHNPDFIVPVEIEGTIHQVYVVKRPFVDDFLRAIAEKFEIVVFTASLAKYADPVLDFLDTGR-VIHYRLFRESC
|||||||||||.||        . ||...|||.| | |...  ..|| |||.|| ||  ... ...|.||||. .||..|.|.||.|| ... |..|..|
ktlvlDlDetlihsahdsvtkstvkpgtapdfvvkvlidkepvlfyvykrPhvDlfLdvvskWydlviftasmeeyaaavvdkLdsgrgilkrryyrqhC

HNHKGNYVKDLSRLGRDLKSTIIVDNSPSSYLFHPENAIPIDSWFDDKDD
 ...|.|.|||| .  ||.|.||.||||..| ..|.|||||.||. | .|
vlesgkytkdlslvssdlssviilDnspvayrknpdnaipikswlsdpsd
CPDc_SM00577 137-277 1.1e-49 160.2 In-house 3-145 (146) alignment 
Range on Protein: 137-277
Range on HMM: 3-145/146.0
KTLVLDLDETLVHS-------SFKPVHNPDFIVPveiegtiHQVYVVKRPFVDDFLRAIAEKFEIVVFTASLAKYADPVLDFLDTGRVIHYR-LFRESCH
|.||||||||||||       ||..|...|....       ..|.|.|||.||.||  .|. ||.|.||.. .||||..||.||  | . || |.|..|.
kvLVlDLdetLvhsanmaepksfsevsptdslae.......tlvlvlkRPyvdeFLkkaaklfelvifTsaskkyadtildllDpkrllkyrvlyRqdcr

NHKGNYVKD-LSRLGRDLKSTIIVDNSPSSYLFHPENAIPIDSWFDDKDD
..||...|| || | .||....|.|||..|.|..||||..| .......|
lvkgkllkddlsllkvdlskvviiDnseestlvnpenalkikpyisalsd
subfamily_CTDSPL2_pd Subfamily CTDSPL2 138-278 2.2e-52 168.8 In-house 1-142 (142) alignment 
Range on Protein: 138-278
Range on HMM: 1-142/142.0
TLVLDLDETLVHSSFKPVHNPDFIVPVEIEGTIHQVYVVKRPFVDDFLRAIAEKFEIVVFTASLAKYADPVLDFLDTGRV-IHYRLFRESCHNHKGNYVK
.|||||||||||.| ...... .  ||. | ...|||| .|||. .||. ... ||...||||   ||| .||.||  .  |..|||||.|   .|||.|
slvldldetlvhcslekleeatltfpvlfenktyqvyvrlrpflreflervsklfevilftaskkvyadklldlldpekklikhrlfrehcvcvdgnyik

DLSRLGRDLKSTIIVDNSPSSYLFHPENAIPIDSWFDDKDDR
||| |||||. |||||||| .. .  || |||.|||.|..|.
dlsilGrdlektiivdnspqafayqlenGipieswfedendk
subfamily_FCP1_pd Subfamily FCP1 138-268 2.8e-13 42.2 In-house 3-139 (146) alignment 
Range on Protein: 138-268
Range on HMM: 3-139/146.0
TLVLDLDETLVHSSFKPV-----HNPDFIVPVEIEGTIHQVYVVKRPFVDDFLRAIAEKFEIVVFTASLAKYADPVLDFLDTGRVIHY-R-LFRESCHNH
.||.|||.||.|.. .|      ..   |   ..  . .  || .|| . .||  ... .|. ..| .  .||. .  .||  . .   | | |. . . 
vLvvDlDqtlihttkdptievkeekkkdikkftlpeekevyyvklRpnlkefleklsklyelhiytmgtraYaeqiakilDpekklfserilsrdellda

KGNYVKDLSRLGRDLKSTIIVDNSPSSYLFHpENAIPI
. .  |  . . .| .  .|.|.    . |. || | .
ssktkklkklfptddsmvviiDDredvWnfa.enlikv
subfamily_TIM50_pd Subfamily TIM50 173-278 6.9e-32 102.3 In-house 21-126 (126) alignment 
Range on Protein: 173-278
Range on HMM: 21-126/126.0
VYVVKRPFVDDFLRAIAEKFEIVVFTASLAKYADPVLDFLDTGRVIHYRLFRESCHNHKGNYVKDLSRLGRDLKSTIIVDNSPSSYLFHPENAIPIDSWF
  . |||.|| || ..||.|||||||.. . .| |..| ||   .|.|||||....  .|. ||||| | |||.  |.||  ..|. ..||||. .. | 
wrfkkrPgvdafleqlaelfeivvftseqgltaaplidkldPkqlimyrlfrdatkyvdGehvkdlsklnrdlskvivvdldkksvklqpenalalkkwe

DDKDDR
 ..||.
Gnaddk