Gene puc in Drosophila melanogaster

Synonym: 0238/03, 1351/08, CG7850, Dmel\CG7850, JNK-DSP, PUC, PUC/MKP, Puc, hrt, l(3)84Eh, l(3)A251.1, l(3)j4E1, vco, Dmel_CG7850, puc

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family DSP
Subfamily DSP10
Protein sequence
ID Type Fasta BLAST phosphatome Note
DmelP015_AA protein Get Run
DmelP015_AA_131-274 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
0044763 (Phosphotyrosine protein) phosphatases II 120-274 2.8e-37 123.5 In-house 9-174 (178) alignment 
Range on Protein: 120-274
Range on HMM: 9-174/178.0
SCSSPAVYDIETHPASPVFPHLLLGNGRDADDPS---SVGANCVLNVTCQSP------NESHLQ--GLKYMQIPASDTPHQNIKQYFQEAYDFIEDAR-K
 .. . .  .. ..|| ..|.|.||.  .|||.      | ....|.|   .      .. ...  |..|..|| .| . ... ..|.|...|||.|. .
lsnleglersdyinaseilpglylgslppaddlellkelgithivnlteelelgflkcdpywpeeagiqylhipipDhgvpdllehflefvefieealde

TGSRVLLHCHAGISRSATIAIAYVMRYKSLSLLEAYKLVKVARPiISPNLNFMGQLLELEQNLRKSG
 |..|| ||.||..||.|...|| |.. .||| ||..||. .|| |.|| ... ||.|.|. |.| .
kggpvlVHCsaGvgRsgtlvaaylmkklglsleeaielvrerRp.ivpnpgqlrqLyefelrllkes
subfamily_DSP10_pd Subfamily DSP10 122-274 8.6e-73 237.4 In-house 2-157 (159) alignment 
Range on Protein: 122-274
Range on HMM: 2-157/159.0
SSPAVYDIETHPASPVFPHLLLGNGRDADDPSSV---GANCVLNVTCQSPNESHLQGLKYMQIPASDTPHQNIKQYFQEAYDFIEDARKTGSRVLLHCHA
.||. .||||.|||.|.|.|.||...||.| ...   ....|||||...|||.. ..|||..||.||| .||.||||.||..|||.|||.|||||.||.|
lspteadietapasqvlpfLflGsekdaadldaldrlnitavlnvttsvPnefeeealkYkripvsDtskqnlkqyfeealefieearkkgsrvLvhCqa

GISRSATIAIAYVMRYKSLSLLEAYKLVKVARPIISPNLNFMGQLLELEQNLRKSG
|||||||..|||.|....||| .|||.||..||||||||||||||||.|..|.|| 
GisrsatvviaYlmkhlnlslndaykfvkekrpiisPnLnfmGqLlefekelnksk
subfamily_DSP1_pd Subfamily DSP1 125-271 2.3e-38 125.8 In-house 13-157 (163) alignment 
Range on Protein: 125-271
Range on HMM: 13-157/163.0
AVYDiethPASPVFPHLLLGNGRDADDPS---SVGANCVLNVTCQSPNESHLqGLKYMQIPASDTPHQNIKQYFQEAYDFIEDARKTGSRVLLHCHAGIS
 .||    |   . ..| ||   .| . .   | |   .|||. . .|  .   ..|.... .|.|...|...|.|. .||....|.. .||.||.||||
klyd....PvekildfLylGsetvasnleiLkslgitailnvskeldnvfed.lfeYkklkleDspkadislvfeeviefidevkkknGkvlihCqaGis

RSATIAIAYVMRYKSLSLLEAYKLVKVARPIISPNLNFMGQLLELEQNLR
||.|. .||.|. | .|| ||...||  |.|||||..|..|||. |..| 
RsstlclaylmktkrvsleeafdfvkqrRsiisPnagFvlqLlnyekkll
0045098 (Phosphotyrosine protein) phosphatases II 127-272 2.9e-27 91.2 In-house 15-273 (278) alignment 
Range on Protein: 127-272
Range on HMM: 15-273/278.0
YDIETHPASPVFPHLLLGNGR-----------------------------------------DADDPS---SVGANCVLNVT------------------
. . ... | ..|.|.|||.                                           ||.     . | ......|                  
fllllgipseitpalylgnldknRykdilpydhsrVkdYINAsyidgypkkfIatqgPlpstvadfwrmlwelgitvivmltelvelgrekcaqywpegg

---------------------------------CQSPNESHLQGLKYMQIPASDTPHQNIKQYFQEAYDFIEDARK--------------TGSRVLLHCH
                                  ..  . ... |.|. .|  ..|...| ..|.|...||..|.|               | .|| ||.
sltygdftvtllseevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllsslllldsggpvlVHCs

AGISRSATIAIAYVMRYK---SLSLLEAYKLVKVARPI-ISPNLNFMGQLLELEQNLRK
||..|..|...|| |..     ..||||.| ..  ||. . .||... .| |... |..
aGvgRtGtlvaaylmlelleggvdlleavkelrsqRpglavqnleqyrflyefllelll
subfamily_DSP14_pd Subfamily DSP14 132-273 1.2e-42 139.5 In-house 5-147 (157) alignment 
Range on Protein: 132-273
Range on HMM: 5-147/157.0
HPASPVFPHLLLGnGRDADDPSSVGAN---CVLNVTCQSPNeSHLQGLKYMQIPASDTPHQNIKQYFQEAYDFIEDARKTGSRVLLHCHAGISRSATIAI
.  | . |.| |. |. | ... . ..   ...||| . ||  .|........|..|.|.... ..|.|..| ||...|.| ..|.|| ||.||||....
aalsqitpsLfls.gvaalskellkkkkitliinvtvelpn.tklkdiervkvpveDnpeaklakhfdevadkieevkkkggktlvhCvaGvSRSAslcl

AYVMRYKSLSLLEAYKLVKVARPIISPNLNFMGQLLELEQNLRKS
||.|.|..||| ||||||| |||||.||. |  || ..|..|...
aylmkyeklsLreayklvksaRpiirPNvGFwkqlidyEkklkgk
subfamily_Slingshot_pd Subfamily Slingshot 132-269 6e-31 101.1 In-house 17-156 (169) alignment 
Range on Protein: 132-269
Range on HMM: 17-156/169.0
HPASPVFPHLLLGN---GRDADDPSSVGANCVLNVTCQSPNeSHLQGLKYMQIPASDTPHQNIKQYFQEAYDFIEDARKTGSRVLLHCHAGISRSATIAI
. || .| |. ||      . .. .. | . .||||..  |  . . ..|..|   |...... .|..|.|.||| |.|.||.||.||  |.||||.. |
dsaskifdhvylGsewnasnleelkengveyilnvtkeidn.ffpekfeylnirvydeeetdllkywnetykfiekakkkgskvlvhckmGvsrsastvi

AYVMRYKSLSLLEAYKLVKVARPIISPNLNFMGQLLELEQN
|| |.  .||| ||.. ||  | .| || .|. || | |  
ayamkeyglsleealeyvkerrsvikPnkgflkqleeyeGi
0042113 (Phosphotyrosine protein) phosphatases II 132-270 1.7e-22 75.5 In-house 40-242 (245) alignment 
Range on Protein: 132-270
Range on HMM: 40-242/245.0
HPASPV-----FPHLLLGNGRDADDPS-------SVGANCVLNVTCQS---------------------------------------------PNESHLQ
  ||.|      |......|  ....        . | ......|                                                ..  ...
inasyvdgyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywplgesltygdftvtllseehlddytvrtlevtnlgddesre

GLKYMQIPASDTPHQNIKQYFQEAYDFIEDARK--TGSRVLLHCHAGISRSATIAIAYVM-----RYKSLSLLEAYKLVKVARPIISPNLNFMGQLLELE
.. |...|  | .  .. ........|...|..   . .|| ||.||..|..|...|| |     ... .|| ||.| ..  || . ...... .| |..
vihyhylpwpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylmleqlekelgvsleeavkelrsqRpgavqtpsqyrflyeal

QNL
..|
lel
0041856 (Phosphotyrosine protein) phosphatases II 133-272 1.5e-31 104.8 In-house 18-174 (182) alignment 
Range on Protein: 133-272
Range on HMM: 18-174/182.0
PASPVFPHLLLGNGRD--------------ADDPSS---VGANCVLNVTCQS--PNESHLQGLKYMQIPASDTPHQNikqyFQEAYDFIEDARKTGSRVL
. . . ..|.||. ..              ||.       | ....|.|.    |.. . .|..|...|  | .  .    ..|..||||.... | .||
dldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlteelywpellerlgiqylylpwpDhgvpd....ldelldfieevleeggpvl

LHCHAGISRSATIAIAYVMRYKSLSLLEAYKLVKVARP--IISPNLNFMGQLLELEQNLRK
 ||.||..|..|...||.|.....|| ||.|||. .||  .|.|| .|. ||..||  |.|
VHCsaGvgRtgtlvaaylmkklgvsleeavklvrsrRpgmvitpnqyfflqlallellllk
PTEN_1 133-272 5.6e-27 89.8 In-house 36-193 (196) alignment 
Range on Protein: 133-272
Range on HMM: 36-193/196.0
PASP----VFPHLLLGNGRDA----DDPSSVGANCVLNVTCQSPN--------ESHLQGLKYMQIPASDTPHQNIKQYFQEAYDFIEDARK--TGSRVLL
|. |    ....|..|. .|.    |.  . |. .|.|... ...        |   .|..| ..|  | . ... . | ....||| ...   |  || 
psrpllqeideglyrgslkdvaadldnlkedgitlvvnlseeeelsgrsydleeffksgveylhfpieDhgapslselfdicksfiewllsdpngnvVlV

HCHAGISRSATIAIAYVMRYKSLSLLEAYKLVKVARPIISPNLNFMGQLLELEQNLRK
||.||..||.|...|| |... |.  || .||. .|| ..||  .. .||| ...|..
HCkaGlgRsGtvvaayLmykgkltadeAlelvrekRppgapnspsqerlleyfaella
0051082 (Phosphotyrosine protein) phosphatases II 134-266 5.4e-20 67.0 In-house 8-149 (151) alignment 
Range on Protein: 134-266
Range on HMM: 8-149/151.0
ASPVFPHLLLGNGRDADDPSS---VGANCVLNVTC-----QSPNESHLQGLKYMQIPASDTPHQNIKQYFQEAYDFIEDARKT-GSRVLLHCHAGISRSA
.| | ..|....|  ||.       | ....|..        |.  . .|.....||  |.| ... ..|... .|.| .... .  || ||.||..|..
fsyvtgglyrsggpladflellkelgiktivnlrseeergycpeylpelgievlhipildwpdpglplsfdavleflellldkkngpvlvHCsaGkgRTG

TIAIAYVMRyKSLSLLEAYKLVKVARP-IISPNLNFMGQLLEL
|....| |    .|| ||.. ..  || .. ||  |. ||..|
tlvalylml.lgvsleealeeyrlkrpgvvqpnqqflfqlfal
0048076 (Phosphotyrosine protein) phosphatases II 135-270 1e-30 101.7 In-house 5-142 (145) alignment 
Range on Protein: 135-270
Range on HMM: 5-142/145.0
SPVFPHLLLGNGRDADDP---SSVGANCVLNVTCQSPNEShLQGLKYMQIPASDTPHQNIKQYFQEAYDFIEDARKTGSRVLLHCHAGISRSATIAIAYV
| ..|.| ||.  .| |     . |  .|||.|.  ....  .|..|...|  | . ... ....|...|||.|.| | .|| ||.||..|..|...||.
seilpglylgslptaldlellkdlgittvlnltselelle.rlgiqylylpwpDhgvpdllellleflefieealkeggpvlVHCsaGvgRtgtlvaayl

MRYKSLSLLEAYKLVKVARPIISPNLNFMGQLLELEQNL
|.....|| ||..||. .||.. || ... .|.|.|. |
mlllgvsleealelvrsqrpgavpnpgqlrflyefelel
0048179 (Phosphotyrosine protein) phosphatases II 135-268 4.5e-30 99.6 In-house 5-142 (144) alignment 
Range on Protein: 135-268
Range on HMM: 5-142/144.0
SPVFPHLLLGNGRDADDP---SSVGANCVLNVTCQSPNESHLQ-GLKYMQIPASDTPHQNIKQYFQEAYDFIEDARKTGSRVLLHCHAGISRSATIAIAY
| ..|.| ||.  .| |     . | ..|.|.| . ..|.  . |..|...|  | .  .. ....|...|||.|.. | .|| ||.||..|..|...||
seilpglylgslptaldlellkklgittvinlteeyepefleregiqylhlpwpDhgvpdllellleflefieealeeggpvlVHCsaGvgRtgtlvaay

VMRYKSLSLLEAYKLVKVARPIISPNLNFMGQLLELEQ
.|... ||| ||..||. .||.. || ... .|||.|.
lmkklglsleealalvrsrrpgavpnpgqlrfLleyek
subfamily_DSP15_pd Subfamily DSP15 136-269 7.2e-31 101.3 In-house 4-138 (151) alignment 
Range on Protein: 136-269
Range on HMM: 4-138/151.0
PVFPHLLLGNGRDADDPSSVGANCVLNVTC-QSPNESHLQGLKYMQIPASDTPHQNIKQYFQEAYDFIEDARKTGSRVLLHCHAGISRSATIAIAYVMRY
 | | | ||| ||. |   .. . . ..   .  .. .|. ..|  |.|||||.......|.|. .|| ..|  .  ||.|| ||.|||.|...||.|  
kvlpglylgnfrdskdeelLkeknithilsvhdnakkllkdieYkciaasDtpsaklskffkesvefihkcRlkeenvlvhClaGvsRsvtlvvaYlmtv

KSLSLLEAYKLVKVARPIISPNLNFMGQLLELEQN
 .|.  .| . .| || .  ||. |  || | |..
telnwrdalevikaaRsvanPnfGfkrqlkeyekt
subfamily_DSP3_pd Subfamily DSP3 136-272 1.2e-30 100.3 In-house 13-159 (162) alignment 
Range on Protein: 136-272
Range on HMM: 13-159/162.0
PVFPHLLLGNGRDADDPS---SVGANCVLNVTCQS-----PNESHLQ--GLKYMQIPASDTPHQNIKQYFQEAYDFIEDARKT-GSRVLLHCHAGISRSA
 |.|.| .|.   | | |    .|   ||| .  .      .... .  ..||. ....|.|. ....||..| .||..| ..  ..||.||..|.||||
evypklyvgdeavakdkskLkklGithvlnaaegrfskvdtgaefykdleikylGlevdDvpefdlskyFetaakfidealsqkegkvlvhcvvGvsRsa

TIAIAYVMRYKSLSLLEAYKLVKVARPIiSPNLNFMGQLLELEQNLRK
|...||.| .....| || . |.  | |  ||  |. || ||...|..
tlvlayLmirrkmtlveairtvrkkRei.lPneGFlkqLaeldeelkr
subfamily_DSP6_pd Subfamily DSP6 137-272 4.4e-44 143.8 In-house 17-156 (158) alignment 
Range on Protein: 137-272
Range on HMM: 17-156/158.0
VFPHLLLGNGRDADDPSS---VGANCVLNVTCQSPNESHLQG-LKYMQIPASDTPHQNIKQYFQEAYDFIEDARKTGSRVLLHCHAGISRSATIAIAYVM
. |.| ||. .|| .  .   .. . ||||| . ||  . .| |||.|||..|  .||. ..| || .||..||.. | ||.||.|||||| |...||.|
ilpllylGsakdasnlevlkklkikyvlnvtsnlpnkfeesgelkylqipiedhlsqnlakffPeaiefidearskkskvlvhClaGisrsvtvtlaylm

RYKSLSLLEAYKLVKVARPIISPNLNFMGQLLELEQNLRK
... ||| .||.|||  .. ||||.|||||||. |..|| 
kklalslndaydlvkkrksnisPnfnfmgqlldferslrl
subfamily_DSP8_pd Subfamily DSP8 137-272 4.1e-40 130.9 In-house 18-156 (159) alignment 
Range on Protein: 137-272
Range on HMM: 18-156/159.0
VFPHLLLGNGRDADDP---SSVGANCVLNVTCQSPNESHLQGLKYMQIPASDTPHQNIKQYFQEAYDFIEDARKTGSRVLLHCHAGISRSATIAIAYVMR
. ..| ||  .|. .    | .| . |||. .. |. . |.  |....|  |. . .. ..|.....||. |... .|||.|..||||||||.||||.|.
ilknlylGsqkdvlseellsklgisyvlnasnscpkleelkeskflrvPvkDkydekllpwfdksvefidkaksengrvlvhvlaGisrsatvaiayimk

YKSLSLLEAYKLVKVARPIISPNLNFMGQLLELEQNLRK
. ..|| |||. ||  || |||||||.||||| |..|..
tlemsldeayrfvkekrptispnlnflgqLleyekelkl
PTPc_motif_SM00404 137-268 3.3e-39 129.0 In-house 5-139 (140) alignment 
Range on Protein: 137-268
Range on HMM: 5-139/140.0
VFPHLLLGNGRDAD---DPSSVGANCVLNVTCQSPNESHLQGLKYMQIPASDTPHQNIKQYFQEAYDFIEDARKTGSRVLLHCHAGISRSATIAIAYVMR
. ||| ||. ..|      ...|   |.||| . ..... .| ...||| .|.  ... .|.....||||.|.|.| .|| || ||.|||||..|||.||
ilphlylgskskaqnpallkklgithvinvteevsltkensgfqilqiplddnekdklskyldkvldfienaekkggkvlVHCqaGvSRSatliiaYlmr

YKSLSLLEAYKLVKVARPIISPNLNFMGQLLELEQ
|..||| |||..||. ||||||||||. ||.|.|.
yrqlslaeayefvkerRpiispnlnfvrqLieyek
subfamily_DSP19_pd Subfamily DSP19 137-270 9.1e-35 114.2 In-house 15-150 (152) alignment 
Range on Protein: 137-270
Range on HMM: 15-150/152.0
VFPHLLLGNGRDADDPSSVGA---NCVLNVTCQSPNEsHLQGLKYMQIPASDTPHQNIKQYFQEAYDFIEDARKTGSRVLLHCHAGISRSATIAIAYVMR
| |.|.||    | | ...       .|||. . ||  . . ..|..|.  |.| ... .|..|| ||||.||..  .||.||.||.||||...|||.|.
veprlylgsqdvaadkeilkekkitHilnvatgvpnv.fpkdftylsieilDlpetdllsylkealdFieearskdgavlvHCnAGvSRsasvviaylmk

YKSLSLLEAYKLVKVARPIISPNLNFMGQLLELEQNL
 ..||| ||..||. ||| |.||  |. || |.|..|
keelsleealelvrearpcikPneGFikqLkeyeael
subfamily_DSP12_pd Subfamily DSP12 137-264 1.5e-31 103.9 In-house 5-137 (155) alignment 
Range on Protein: 137-264
Range on HMM: 5-137/155.0
VFPHLLLGNGRDADDP---SSVGANCVLNVTCQS-PNESHLQGLK-YMQIPASDTPHQNIKQYFQEAYDFIEDARKTGSRVLLHCHAGISRSATIAIAYV
. | |.||. ... ..   .... . || |. .. |.... .| . . .|.. |.|...| ....|| ||||.|....  || ||.||.|||.|| |||.
ilpglylggleavqeeellkelkithvlsvikeelpehklkkgkvstkfiqilDepeediLshldeavdFieealeeegavlvHCqagvSRSvtiviAYl

MRYKSLSLLEAYKLVKVARPIISPNLNFMGQLL
|... ||| .|.|||| ..| |.|| .|. || 
mkkeklslekAlklvkekkpeiepNegFleQLk
subfamily_STYXL1_pd Subfamily STYXL1 137-271 7.3e-22 71.3 In-house 14-154 (157) alignment 
Range on Protein: 137-271
Range on HMM: 14-154/157.0
VFPH-LLLGNGRDADDPS---SVGANCVLNVTCQS-PNESHLQG-LKYMQIPASDTPHQNIKQYFQEAYDFIEDARKTGSRVLLHCHAGISRSATIAIAY
| |. | ||| ..| .|.    .    ..||. .. .  . ...  | ..|. .|... .. . ..|| .|||. .|.|. ||.  . ||||||...|||
vlPgklylGnykqaqnpaikkdlkvkahvnvsmdadkliagvadvakllhiavedeneadllerlkeavqfiekhkkegevvlvfsnkGisrsaaviiay

VMRYKSLSLLEAYKLVKVARPIISPNLNFMGQLLELEQNLR
.| .| ..| .||| .|  .. . || .|. || | |..| 
lmyskkitlkkaykylkkCkenvkPnrafveqlseWekqll
subfamily_Choan-DSP_MKP-1_pd Subfamily Choan-DSP_MKP-1 138-269 1.5e-29 96.4 In-house 12-146 (148) alignment 
Range on Protein: 138-269
Range on HMM: 12-146/148.0
FPHLLLGNGRDADDPSSV---GANCVLNVTCQSPNESHLQGLKYMQIPASDTPHQNIKQYFQEAYDFIEDARKTGSRVLLHCHAGISRSATIAIAYVMRY
  .| ||. . | | . .   |   . | | . .|    .|..|.... .| |.......|... .|.. |.. | |||.|.. |.|||. .|.......
dafLFlGskksaadlealkalgvtrivnatkerdnaldqrgieYlhvaldDkpkedlsaiFediiafvrkakdeGrrvLvhlqmGvsrssalallwlidf

KSLSLLEAYKLVKVARPIISPNLNFMGQLLELEQN
|  || ||. ||| .|. . ||| |. || ||||.
krvslkealalvkskrryvdpnlgfLkqLaeleqa
0046846 (Phosphotyrosine protein) phosphatases II 153-272 2.8e-26 87.7 In-house 44-174 (176) alignment 
Range on Protein: 153-272
Range on HMM: 44-174/176.0
SSVGANCVLNVT----------CQSPNESHLQGLKYMQIPASDTPHQNIkQYFQEAYDFIEDARKTGSRVLLHCHAGISRSATIAIAYVMRY-KSLSLLE
 . | ..|.|.|          .. ..| .  |..|...|  |    .. ....|...||..|.| | .|| ||.|||.|..|...|| ... | ||..|
kelgitavvnlteevelgrlkcpnywpeleklgiqylhlpwpDhgvpdl.elllellefirealkeggpvlVHCsaGigRtgtlvaayllelekglsvee

AYKLVKVARP-IISPNLNFMGQLLELEQNLRK
|..||.  ||  . .. ... .| | |. |.|
alalvreqRplgavqtpeQyrflyefellllk
0043147 (Phosphotyrosine protein) phosphatases II 155-270 1.3e-28 95.2 In-house 43-160 (172) alignment 
Range on Protein: 155-270
Range on HMM: 43-160/172.0
VGANCVLNVTcQS---PNESHLQGLKYMQIPASDTPHQnIKQYFQEAYDFIED--ARKTGSRVLLHCHAGISRSATIAIAYVMRyKSLSLLEAYKLVKVA
 | ....|.| .    |   . .|..|. .|  | . . . ....|...||..  |.. | .|| ||.||..|..|...|| |. ..|||.||..||. .
lgithivnlt.ellydpellerlgiqylylpwpDhgvp.llellleflefidellalspggpvlVHCsaGvgRtgtlvaaylml.lglsleeavalvrek

RPIISPNLNFMGQLLELEQNL
||....| ... .|...|. |
Rpgavqnpsqyrflyyfekll
0049260 (Phosphotyrosine protein) phosphatases II 155-270 2.4e-26 87.7 In-house 32-149 (152) alignment 
Range on Protein: 155-270
Range on HMM: 32-149/152.0
VGANCVLNVTCQSPNE--SHLQGLKYMQIPASDTPHQNIKQYFQEAYDFIED-ARKTGSRVLLHCHAGISRSATIAIAYVMRyKSLSLLEAYKLVKVARP
 |.......|  ...    . |. .|...|  | . ... |.......|||  |.. | .|| ||.||..|..|...|| |. . .||.||..||. .||
lgittivmltellelgklkceqyiqylhlpwpDhgvpdlsqlllflllfieklaldkggpvlVHCsaGvgRtgtlvaaylml.lgvsleeavalvrekRp

IISPNLNFMGQLLELEQNL
.. || ... .|.| |. |
gavpnpgqlrflyefekll
0037934 (Phosphotyrosine protein) phosphatases II 155-270 3.3e-25 84.5 In-house 71-241 (243) alignment 
Range on Protein: 155-270
Range on HMM: 71-241/243.0
VGANCVLNVTCQS--------------------------------------------PNESHLQGLKYMQIPASD----TPHQNIKQYFQEAYDFIED--
 | ......|                                               ... .... .|...|  |    . .... ....|...|||.  
lgitvivmltelvElgrekcaqywpgevtygdftvtllseehlddytvrtlllenldlddltrlvihyhylpwpdhgvPdspedlldfldevrefieell

---ARKTGSRVLLHCHAGISRSATIAIAYVMRYK-SLSLLEAYKLVKVARPI-ISPNLNFMGQLLELEQNL
   |...|..||.||.||..|..|...||.| .. ...|.||.||..  ||  . ...... .| |... |
sllaldsggpvlVHCsaGvgRtGtliaaylmllllgvdleeavkllreqRpgkavqtpsqyrflyeallel
0040439 (Phosphotyrosine protein) phosphatases II 156-271 1.3e-24 82.6 In-house 78-246 (249) alignment 
Range on Protein: 156-271
Range on HMM: 78-246/249.0
GANCVLNVTCQSPNE------------------------------------------SHLQGLKYMQIPASDTPHQNIKQYFQEAYDFIEDARK------
| ......|   ...                                           . . .....|.  | |.... ..|... |||| .||      
gitvivmLtslvelgrekcaqywplggsleygdftvtllsvevkddytvrtleltnlydgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleelp

TGSRVLLHCHAGISRSATIAIAYVM-----RYKSLSLLEAYKLVKVARPIISPNLNFMGQLLELEQNLR
.|..|| ||.||..|..|...|| |     ... ..|.||.||.. .|| . .|.... .|.|... |.
kggpvlVHCsaGvgRtGtfiaaylmleqlekelgvdleeavkllrsqRpgavqnpeqyrflyeallell
DSPc Dual specificity phosphatase, catalytic domain 157-268 2e-36 119.8 Pfam-A 19-132 (133) alignment 
Range on Protein: 157-268
Range on HMM: 19-132/133.0
ANCVLNVT--CQSPNESHLQGLKYMQIPASDTPHQNIKQYFQEAYDFIEDARKTGSRVLLHCHAGISRSATIAIAYVMRYKSLSLLEAYKLVKVARPIIS
 . |.|||  .. .|... .  .|..||  |.  ..| ....||..|||.|.. | .|| || ||||||||..||| |..|.||| |||..||  |..||
itlvinvtkevpnnnaikkseieylripvedetetkiskeleeavefiekaeqkgkkvlVHCqaGisRSatliiaYlmktknlslneAyefvkerrskis

PNLNFMGQLLELEQ
|| .|..||||.|.
pnagflrqLleyer
DSPc Dual specificity phosphatase, catalytic domain 157-268 2e-36 119.8 In-house 19-132 (133) alignment 
Range on Protein: 157-268
Range on HMM: 19-132/133.0
ANCVLNVT--CQSPNESHLQGLKYMQIPASDTPHQNIKQYFQEAYDFIEDARKTGSRVLLHCHAGISRSATIAIAYVMRYKSLSLLEAYKLVKVARPIIS
 . |.|||  .. .|... .  .|..||  |.  ..| ....||..|||.|.. | .|| || ||||||||..||| |..|.||| |||..||  |..||
itlvinvtkevpnnnaikkseieylripvedetetkiskeleeavefiekaeqkgkkvlVHCqaGisRSatliiaYlmktknlslneAyefvkerrskis

PNLNFMGQLLELEQ
|| .|..||||.|.
pnagflrqLleyer
subfamily_MKPLT_pd Subfamily MKPLT 157-268 1.9e-23 76.8 In-house 48-158 (164) alignment 
Range on Protein: 157-268
Range on HMM: 48-158/164.0
ANCVLNVTcQSPNESHLQGLKYMQIPASDTPHQNIKQYFQEAYDFIEDARKTGSRVLLHCHAGISRSATIAIAYVMRYKSLSLLEAYKLVKVARPIISPN
 . ..||. |  ..   . ..|.|.  .|...... .... | .|. || ..| |||.||  | |||.....|.....|   | |||. .|  | |..||
ithivnvs.qekkdafpksveYlqvkvedesdeqlssfleraakfladaidsGGrvlvhcvqGksrsssvtvafLikskgwtlkeayeylkerrsivapn

LNFMGQLLELEQ
  |. || . |.
rGflkqlakfee
subfamily_MKPLV_pd Subfamily MKPLV 157-268 1.9e-23 76.8 In-house 48-158 (164) alignment 
Range on Protein: 157-268
Range on HMM: 48-158/164.0
ANCVLNVTcQSPNESHLQGLKYMQIPASDTPHQNIKQYFQEAYDFIEDARKTGSRVLLHCHAGISRSATIAIAYVMRYKSLSLLEAYKLVKVARPIISPN
 . ..||. |  ..   . ..|.|.  .|...... .... | .|. || ..| |||.||  | |||.....|.....|   | |||. .|  | |..||
ithivnvs.qekkdafpksveYlqvkvedesdeqlssfleraakfladaidsGGrvlvhcvqGksrsssvtvafLikskgwtlkeayeylkerrsivapn

LNFMGQLLELEQ
  |. || . |.
rGflkqlakfee
0036282 (Phosphotyrosine protein) phosphatases II 157-270 1.2e-22 75.9 In-house 37-169 (174) alignment 
Range on Protein: 157-270
Range on HMM: 37-169/174.0
ANCVLNVTCQSPN--------------ESHLQGLKYMQIPASDTPHQNIKQyFQEAYDFIEDARKT--GSRVLLHCHAGISRSATIAIAYVMRYKSL-SL
 ..|....   ..                .  |..|...|  |    .. . ..|...|.|.|..   |  || ||.||..|..|...|| | .  | ||
ittvvmlleekelglykcinywpelredlerlgiqylylpwpDhgvpdlsi.llefvkfveealsedpggpvlVHCsaGvgRtGtlvaaylmlrgllesl

LEAYKLVKVAR---PIISPNLNFMGQLLELEQNL
 .|..||. .|   | . .. ... .| ..|. |
vdaldlvrelRlqrpgmvqtpsQyrflyyfekll
0051429 (Phosphotyrosine protein) phosphatases II 158-270 4.1e-16 54.9 In-house 47-224 (272) alignment 
Range on Protein: 158-270
Range on HMM: 47-224/272.0
NCVLNVTCQS-----PNESHLQGLKYMQIPASDTPHQNIK---------------------------------------------------QYFQEAYDF
.......  .     . . ...|..|...|  |. .. |                                                    ... |. ..
ktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseellldyilrellltlllsagearevmhlhytdwpdhgvpqeallellel

IEDarktGSRVLLHCHAGISRSATIAIAYVMRyKSLS--------------LLEAYKLVKVARPIISPNLNFMGQLLELEQNL
. |    | .|| ||.||..|..|.. .. .    .|              |.||.. .. .|| . ..  .. .|.| ...|
lld....ggpvlvHCsaGkdRTGtvvalllll.lgvsletivddYlltnlyleeaveelraqrpgavqteeqylflyeallel
0045450 (Phosphotyrosine protein) phosphatases II 159-271 5.7e-25 84.1 In-house 134-304 (307) alignment 
Range on Protein: 159-271
Range on HMM: 134-304/307.0
CVLNVTCQSPNE---------------------------SHLQGLKYMQIPASDT-----------------PHQNIKQYFQEAYDFIEDARK------T
.....|   ...                           .||.|....... .|.                 |.... ..|.|. |||| .||       
vivmltelvelgrekcaqywPdegeeltygnftvtllseehldgytvrtlevtdldgtgesrtvthfhytgwpdhgvppsfeelldfieevrkaleelpk

GSRVLLHCHAGISRSATIAIAYVMRYKS--------LSLLEAYKLVKVARPIISPNLNFMGQLLELEQNLR
|..|| ||.||..|..|...||.| .          ..||||.||..  || . .|.... .| |... | 
ggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrflyeallell
0038934 (Phosphotyrosine protein) phosphatases II 159-273 1e-19 66.4 In-house 59-179 (194) alignment 
Range on Protein: 159-273
Range on HMM: 59-179/194.0
CVLNVTCQ----SPNESHLQGLKYMQIPASD---TPHQNIKQYFQEAYDFIEdARKTGSRVLLHCHAGISRSATIAIAYVMRYKSLSLLEAYKLVKVARP
.|...|.     .|.| .  |..|...|  |   .| ..| . | .. |..  ....|  |. ||.||..|..|...|| . .  .|. ||..|.. .||
lvidltnteryYdpeefekagieylklpfpddgtvPsleillrfldlvdefl.nedpggvvaVHCkaGlgRtGtlvaaYLiyrlgmsaeeAialfrekRp

IISPNLNFMGQLLELEQNLRKS
 . || ... .||.  ..|||.
gaipnqdyleallkrykelrka
0043336 (Phosphotyrosine protein) phosphatases II 161-268 4.3e-17 57.9 In-house 162-274 (278) alignment 
Range on Protein: 161-268
Range on HMM: 162-274/278.0
LNVTC-QSPNESHLQGLKYMQIPASDTPHqNIKQYFQEAYDFIEDARKTGSRVLLHCHAGISRSATIAIAYVM-----RYKSLSLLEAYKLVKVARPIIS
|.||  ..... . ... |. .|  ..|. .......   ...|  .. .. || ||.||..|..|....|..     ... ..|.||.| ..  || . 
levtnlgdgesrtvthyhylgwpdhgvpe.slsllldflkavrealedsngpvlVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqRpgav

PNLNFMGQLLELEQ
...... .| |...
qtpsqyrflyeall
0040438 (Phosphotyrosine protein) phosphatases II 162-276 1.9e-23 78.7 In-house 116-281 (317) alignment 
Range on Protein: 162-276
Range on HMM: 116-281/317.0
NVTCQS--------------------------PNESHLQGLKYMQIPASDT----------------PHQNIKQYFQEAYDFIEDARKT----GSRVLLH
..|                              .| .|.| .. ... .|.                |.... .....  ||.| .|.     |. || |
mLteleelgrekcaqYwplgetltygdftvtllseeelagitlrtlevedlgdsesrtvthfhytgWpdhgvppspdllldfleavrealedpggpvlVH

CHAGISRSATIAIAYVM-----RYKSLSLLEAYKLVKVARPIISPNLNFMGQLLELEQNLRKSGVL
|.||..|..|...||.|     ... ... ||.| .. .|| . ...... .| ...... | .. 
CsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrflydalleylkrklt
subfamily_PTPMT1_pd Subfamily PTPMT1 162-258 2.4e-18 61.1 In-house 60-156 (171) alignment 
Range on Protein: 162-258
Range on HMM: 60-156/171.0
NVTCQSPNESHLQGLKYMQIPASDTPHQNIKQYFQEAYDFIEDARKTGSRVLLHCHAGISRSATIAIAYVMRYKSLSLLEAYKLVKVARPIISPNLN
.. ..| .| . .|....|..  |  ..   .  ... .|||. ...|.|| .||.|| .||||....|.|  . ||. || | .|  |.||  . .
kalansteewkklgveqlqlatvDfteapdleklekgvefiekvaskgkrvYvHCkaGrgRsatlvacylmkkeklspeeAlkalkkkRkiirlakk
subfamily_Sponge-DSP-Subfam1_pd Subfamily Sponge-DSP-Subfam1 168-272 4.3e-23 75.0 In-house 39-143 (145) alignment 
Range on Protein: 168-272
Range on HMM: 39-143/145.0
PNESHLQGLKYMQIPASDTPHQNIKQYFQEAYDFIEDARKTGSRVLLHCHAGISRSATIAIAYVMRYKSLSLLEAYKLVKVARPIISPNLNFMGQLLELE
 .|.. . .. . | |.|    .. |.|.|  |||.  .. |. |..|| ||.||| |...|..|.| ...| || . |.  |    ||..|. .||.||
sqelksesieillitaedlesydlsqhfdevtdfidkgkeegagvfvhcmagvsrsvtvsvaflmkycnmtlseaarqvrsnrllaypnvtflknllnle

QNLRK
..|..
kqlke
0049772 (Phosphotyrosine protein) phosphatases II 169-269 6.9e-31 103.5 In-house 174-272 (314) alignment 
Range on Protein: 169-269
Range on HMM: 174-272/314.0
NESHLQGLKYMQIPASDtPHQNIKQYFQEAYDFIEDArKTGSRVLLHCHAGISRSAT-IAIAYVMRYKSLSLLEAYKLVKVARPiISPNLNFMGQLLELE
.    .|.||..|| .| ..... ..|.|...|||.| ..|..|| ||.||..|..| ...||.|..  .|| ||.. |. .|| |.|| .|. ||...|
elferlgikylripvpD.gsaplledfdeflefieea.dkggpvlvHCkaGkgRtgtfvvaaylmkllgvsleealedvrlkRp.inpnpgfieqleqye

QN
. 
fi
Y_phosphatase Protein-tyrosine phosphatase 169-232 5.8e-06 21.3 Pfam-A 131-193 (235) alignment 
Range on Protein: 169-232
Range on HMM: 131-193/235.0
NESHLQGLKYMQIPASDTPhQNikqyFQEAYDFIEDARKTG----SRVLLHCHAGISRSATIAIAYVM
.. ... | | . | ...| ..     ..  |.|.. .|.     . |. || ||..|..|.. . ..
ekrevkqlhytnWpdhgvp.es....pkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldil
Y_phosphatase Protein-tyrosine phosphatase 169-232 5.8e-06 21.3 In-house 131-193 (235) alignment 
Range on Protein: 169-232
Range on HMM: 131-193/235.0
NESHLQGLKYMQIPASDTPhQNikqyFQEAYDFIEDARKTG----SRVLLHCHAGISRSATIAIAYVM
.. ... | | . | ...| ..     ..  |.|.. .|.     . |. || ||..|..|.. . ..
ekrevkqlhytnWpdhgvp.es....pkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldil
0046845 (Phosphotyrosine protein) phosphatases II 170-256 2.2e-11 39.2 In-house 164-259 (284) alignment 
Range on Protein: 170-256
Range on HMM: 164-259/284.0
ESHLQGLKYMQIPASDTP--HQNIKQYFQEAYDFIEDaRKTGSRVLLHCHAGISRSATIAIAYVMRYK--------SLSLLEAYKLVKVARPIISPN
. ... . |...|  ..|   ... ...... ...|. ...|. .. ||.||..|..|....... .          ...|||.| ..  ||    .
srtvthfhytswpdhgvppspedlleflrlvrellen.lpgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvqt
0039614 (Phosphotyrosine protein) phosphatases II 171-272 9.6e-20 66.7 In-house 164-290 (297) alignment 
Range on Protein: 171-272
Range on HMM: 164-290/297.0
SHLQGLK-------------------YMQIPasDTPHQNIKQYFQEAYDFIEDARK---TGSRVLLHCHAGISRSATIAIAYVM-----RYKSLSLLEAY
 ||.| .                   |. .|  |    .. ....|.......|..    | .|| ||.||..|..|...|| |     ... ...|||.
ehldgytvrtlevtnngesrtvthfqytgwp..dhgvppslellleflelvrealaelpkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleav

KLVKVARPIISPNLNFMGQLLELEQNLRK
| .. .|| . ...... .| .... |.|
kelreqRpgavqtpsqyrflydallellk
subfamily_LRR-DSP_pd Subfamily LRR-DSP 172-272 1.7e-28 93.4 In-house 160-260 (263) alignment 
Range on Protein: 172-272
Range on HMM: 160-260/263.0
HLQGLKYMQI-PASDTPHQNIKQYFQEAYDFIEDARKTGSrVLLHCHAGISRSATIAIAYVMRYKSLSLLEAYKLVKVARPIISPNLNFMGQLLELEQNL
. . .||. |  . |... .| |.|.|   |||. || |  ||.|| ||.|||.|. |.|.|....| . ||. ||.  || | ||  |. ||.  |..|
fPklfkylsiddiedvdeadisqhfeetnafieeGrkkGG.vlvhcraGvsrsstlvisylmkkqrlkfkealdlvikkrpriqPnpGfkdqlkkyekkl

RK
 .
fc
subfamily_RNGTT_pd Subfamily RNGTT 173-281 2.6e-06 21.2 In-house 75-184 (189) alignment 
Range on Protein: 173-281
Range on HMM: 75-184/189.0
LQGLKYMQIPAS---DTPHQNIKQYFQEA-YDFIEdaRKTGSRVLLHCHAGISRSATIAIAYVMRYKSLSLLEAYKLVKVARPIISPNLNFMGQLLELEQ
 .| ||...      ..|...  . |..   .|..  ... . . .||. |  |.  ....|..  .. |. .| .| . |||    . ... .||.  .
kegikyvklqcagkgeaPeaeqvkefiklveeffk..knpeevigvhCthGfnRtGFlivsyLvekedwsveaavalFakaRppGiykedylkellrrYa

NLrKSGVLAPATP
.  .. . ||  |
dv.eeaiaapelp
subfamily_STYX_pd Subfamily STYX 174-268 1.3e-19 63.8 In-house 61-155 (166) alignment 
Range on Protein: 174-268
Range on HMM: 61-155/166.0
QGLKYMQIPASDTPHQNIKQYFQEAYDFIEDARKTGSRVLLHCHAGISRSATIAIAYVMRYKSLSLLEAYKLVKVARPIISPNLNFMGQLLELEQ
. ..|. .  .|.. .|| .|. .  .||.|. ..| .||.|  |||||||.. |||.|    |   ||.. |.  |  |.||  |. || | | 
drfrylvldvadntveniirylptvkefiddslqkggkvlvhgnagisrsaalviayimetyglkyreafayvqerrfcinpnegfvsqlkeyea
0051299 (Phosphotyrosine protein) phosphatases II 174-258 3.5e-13 45.1 In-house 180-273 (288) alignment 
Range on Protein: 174-258
Range on HMM: 180-273/288.0
QGLKYMQIPASDTPHQNIKQYFQEAYDFIEDARKT----GSRVLLHCHAGISRSATIAIAYVM-----RYKSLSLLEAYKLVKVARPIISPNLN
. ......   . |.... .....  ||....||     |. |. ||.||..|..|.......     . . ...|||.| ..  || . ....
esrtvthfhytnwpdhgvpdspellldflrlvrkalasgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlreqRpgmvqtpe
subfamily_Laforin_pd Subfamily Laforin 174-252 6.2e-06 19.2 In-house 75-153 (183) alignment 
Range on Protein: 174-252
Range on HMM: 75-153/183.0
QGLKYMQIPASDTPHQNIKQYFQEAYDFIEDARKTGSRVLLHCHAGISRSATIAIAYVMRYKSLSLLEAYKLVKVARPI
.|| |. .|  |   ..  . . .|  ..    . | .| .|| ||. ||..|   ...     ||      .   ||.
eglayiwlptedlstesrvenlpqavyllhallekghivyvhcnagvgrstaivcgflqyvlgwslakvqyfllakrpv
subfamily_MSG5_pd Subfamily MSG5 175-272 7.8e-19 61.4 In-house 67-162 (165) alignment 
Range on Protein: 175-272
Range on HMM: 67-162/165.0
GLKYMQIPASDTphQNIKQYFQEAYDFIEDARKTGSRVLLHCHAGISRSATIAIAYVMRYKSLSLLEAYKLVKVARPIISPNLNFMGQLLELEQNLRK
 .||  |    .   .| . . .    |  |.  . ..|.||  |.||||.. .||.|.| .||| .||...|     |||.. .. ||.| |  | |
avkyyhiewehd..skivkdlsrltriihaatskrkkilvhcqcglsrsaslivayimkyynlslrdaydklksvaddispsiglifqlmewevalsk
subfamily_Dicty-DSP19-like_pd Subfamily Dicty-DSP19-like 176-271 8.2e-26 84.2 In-house 56-153 (154) alignment 
Range on Protein: 176-271
Range on HMM: 56-153/154.0
LKYMQIPASDTPHQNIKQYFQEAYDFIEDAR--KTGSRVLLHCHAGISRSATIAIAYVMRYKSLSLLEAYKLVKVARPIISPNLNFMGQLLELEQNLR
..|...   | ....| . .. |..||.||      ..||.|...|.||||...|.|.|  ...|| .|..|.| .|.||.||  |. ||   |..|.
ieylnlelfddvnfdiiekldkafefiddaiggvennkvlvhsdkGvsrsaallisylmdklkislslalellkdsryiikPnqGflkqleifekell
0050432 (Phosphotyrosine protein) phosphatases II 176-257 2.7e-12 42.1 In-house 197-285 (308) alignment 
Range on Protein: 176-257
Range on HMM: 197-285/308.0
LKYMQIPASDTPHQNIKQYFQEAYDFIEDARKT--GSRVLLHCHAGISRSATIAIAYVM-----RYKSLSLLEAYKLVKVARPIISPNL
......   . |.... .....  ||.| .||.  |. .. ||.||..|..|.......     . . ....||.| ..  ||   ...
rtvthfhytnWpdhgvPpspeilldflelvrkslpggpivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkklReqRpgmvqtp
PTPc_DSPc_SM00012 176-233 1.9e-08 29.8 In-house 5-63 (105) alignment 
Range on Protein: 176-233
Range on HMM: 5-63/105.0
LKYMQIPASDTPH--QNIKQYFQEAYDFIEDARKtGSRVLLHCHAGISRSATIAIAYVMR
..|...|   .|.  ..| .....  .. ... . .. |..||.||..|..|.. .... 
yhytgwpdhgvPeesdsilellravkknknkses.skpvvVhCsaGvgRtgtfvaldill
0036941 (Phosphotyrosine protein) phosphatases II 177-273 2.5e-20 68.4 In-house 169-279 (297) alignment 
Range on Protein: 177-273
Range on HMM: 169-279/297.0
KYMQIPASDTPHQNIKQYFQEAYDFIEDARK------TGSRVLLHCHAGISRSATIAIAYVM--------RYKSLSLLEAYKLVKVARPIISPNLNFMGQ
. ...   . |. .. .....  |||| .||       |..|| ||.||..||.|...|..|        ... ...|||.| ..  || . ..|... .
tvthfhytgwpdhgvpespaslldfielvrkvlkllpsggpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrf

LLELEQNLRKS
| |....| |.
lyeallellkk
0047943 (Phosphotyrosine protein) phosphatases II 177-264 1.2e-14 49.9 In-house 167-265 (273) alignment 
Range on Protein: 177-264
Range on HMM: 167-265/273.0
KYMQIPASDTPHQNIKQYFQEAYDFIEDARK------TGSRVLLHCHAGISRSATIAIAYVM-----RYKSLSLLEAYKLVKVARPIISPNLNFMGQLL
.....   . | ... .....  .|||..||       .. |. ||.||..|..|.......     ... ...|||.||..  || . ...... .| 
tvthfhytgwpdhgvppslesllefielvrkalealpsngpvvVHCsaGvgRtgtfialdllldqlekeggvdvleavkllrsqRpgmvqtpeqyrfly
0048567 (Phosphotyrosine protein) phosphatases II 190-251 2e-08 28.7 In-house 55-119 (157) alignment 
Range on Protein: 190-251
Range on HMM: 55-119/157.0
NIKQYFQEAYDFIEDARKTGSRVLLHCHAGI---SRSATIAIAYVMRYKSLSLLEAYKLVKVARP
 . .... ...|... ...| .. .||.||    .|.||.. .| . . ...  ||.......||
ilyrFilklnkflkilelagkaiavhckaglkkrgrtatLigcYlilhlgftpeeaiaplrivrp
subfamily_CDC14_pd Subfamily CDC14 200-260 1.6e-06 22.2 In-house 254-316 (328) alignment 
Range on Protein: 200-260
Range on HMM: 254-316/328.0
DFIEDARKTGSRVLLHCHAGISRSATIAIAYVMRYKSLSLLEAYKLVKVARP--IISPNLNFM
 |.| | |.   . .||.||. |  |.  .|.|.   ..  ||   ....||  .|.|  .|.
kfleiaekaeGaiavhCkaGLGrtGtLiacylmkhyrftaaeaiawlricrPGsvigpqqkfl