Gene CG10089 in Drosophila melanogaster

Synonym: Dmel\CG10089, Dmel_CG10089, CG10089

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family DSP
Subfamily DSP15
Protein sequence
ID Type Fasta BLAST phosphatome Note
DmelP019_AA protein Get Run
DmelP019_AA_2-146 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
0044763 (Phosphotyrosine protein) phosphatases II 3-144 4e-35 116.4 In-house 21-172 (178) alignment 
Range on Protein: 3-144
Range on HMM: 21-172/178.0
NGMNKVLPGLYVGNYRDSKDHAQLERFKISHIIAIHDSPRRLLPD----------KHYLCVMASDTPDQNLSQYFSVCNDFIHAAR-LREGNVLIHCLAG
......|||||.|.. ...| ..| . .|.||. . .  ..  ..           .||..  .| ....|...|  . .||..|.  ..|.||.|| ||
inaseilpglylgslppaddlellkelgithivnlteelelgflkcdpywpeeagiqylhipipDhgvpdllehflefvefieealdekggpvlVHCsaG

MSRSVTVAVAYIMTATHLNWKEALKVVRAGRAvANPNAGFQSQLQEFEQFKLS
..|| |...||.|   .|.. ||.. ||. |  ..|| |.. ||.|||.. |.
vgRsgtlvaaylmkklglsleeaielvrerRp.ivpnpgqlrqLyefelrllk
0048179 (Phosphotyrosine protein) phosphatases II 3-140 3.4e-31 103.3 In-house 2-142 (144) alignment 
Range on Protein: 3-140
Range on HMM: 2-142/144.0
NGMNKVLPGLYVGNYRDSKDHAQLERFKISHIIAIHDS---PRRLLPDKHYLCVMASDTPDQNLSQYFSVCNDFIHAARLREGNVLIHCLAGMSRSVTVA
. ....|||||.|.. ...| ..| ...|...| . ..   .    .  .||..   | .  .|....  . .||..|. ..|.||.|| ||..|. |..
snpseilpglylgslptaldlellkklgittvinlteeyepefleregiqylhlpwpDhgvpdllellleflefieealeeggpvlVHCsaGvgRtgtlv

VAYIMTATHLNWKEALKVVRAGRAVANPNAGFQSQLQEFEQ
.||.|   .|...|||. ||. |  |.|| |.  .|.|.|.
aaylmkklglsleealalvrsrrpgavpnpgqlrfLleyek
0046846 (Phosphotyrosine protein) phosphatases II 3-142 9.9e-24 79.5 In-house 10-172 (176) alignment 
Range on Protein: 3-142
Range on HMM: 10-172/176.0
NGMNKVLPGLYVGNYR----------DSKDHAQLERFKISHIIAIHDS------------PRRLLPDKHYLCVMASDTPDQNLsQYFSVCNDFIHAARLR
.... ....|..|..             .. ..| . .|.... . .             |.   .. .||..   |    .| ...  . .||. |. .
ldldyinanlilgsrpiatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpeleklgiqylhlpwpDhgvpdl.elllellefirealke

EGNVLIHCLAGMSRSVTVAVAYIMTA-THLNWKEALKVVRAGRA-VANPNAGFQSQLQEFEQFK
 |.||.|| ||..|. |...||..    .|.. |||. ||. |   | .. ..  .|.|||.. 
ggpvlVHCsaGigRtgtlvaayllelekglsveealalvreqRplgavqtpeQyrflyefelll
subfamily_DSP15_pd Subfamily DSP15 4-154 8.2e-73 237.5 In-house 1-151 (151) alignment 
Range on Protein: 4-154
Range on HMM: 1-151/151.0
GMNKVLPGLYVGNYRDSKDHAQLERFKISHIIAIHDSPRRLLPDKHYLCVMASDTPDQNLSQYFSVCNDFIHAARLREGNVLIHCLAGMSRSVTVAVAYI
|..|||||||.||.|||||...|.. .|.||...||....||.|..|.|..|||||...||..|. ...|||..||.|.|||.|||||.|||||..|||.
giskvlpglylgnfrdskdeelLkeknithilsvhdnakkllkdieYkciaasDtpsaklskffkesvefihkcRlkeenvlvhClaGvsRsvtlvvaYl

MTATHLNWKEALKVVRAGRAVANPNAGFQSQLQEFEQFKLSEERRRLRERF
||.|.|||..||.|..| |.|||||.||..||.|.|..||.|.|..|.|.|
mtvtelnwrdalevikaaRsvanPnfGfkrqlkeyektklkeyrkqlkeef
subfamily_DSP14_pd Subfamily DSP14 4-141 3.9e-34 111.9 In-house 6-143 (157) alignment 
Range on Protein: 4-141
Range on HMM: 6-143/157.0
GMNKVLPGLYVGnYRDSKDHAQLERFKISHIIAIH-DSPRRLLPDKHYLCVMASDTPDQNLSQYFSVCNDFIHAARLREGNVLIHCLAGMSRSVTVAVAY
..... | |...  . ......|.. ||..|| .  . | . |.| ... |...|.|...|...|    | |.... ..|..|.|| ||.||| ....||
alsqitpsLfls.gvaalskellkkkkitliinvtvelpntklkdiervkvpveDnpeaklakhfdevadkieevkkkggktlvhCvaGvSRSAslclay

IMTATHLNWKEALKVVRAGRAVANPNAGFQSQLQEFEQF
.|   .|. .|| |.|.. | . .|| || .||...|. 
lmkyeklsLreayklvksaRpiirPNvGFwkqlidyEkk
0048076 (Phosphotyrosine protein) phosphatases II 4-141 3.3e-31 103.3 In-house 3-141 (145) alignment 
Range on Protein: 4-141
Range on HMM: 3-141/145.0
GMNKVLPGLYVGNYRDSKDHAQLERFKISHIIAI-HDSPRRLLPDKHYLCVMASDTPDQNLSQYFSVCNDFIHAARLREGNVLIHCLAGMSRSVTVAVAY
.....|||||.|.. . .| ..|....| ... . .. .     . .||..   | . ..|....  . .||..|. ..|.||.|| ||..|. |...||
wpseilpglylgslptaldlellkdlgittvlnltselellerlgiqylylpwpDhgvpdllellleflefieealkeggpvlVHCsaGvgRtgtlvaay

IMTATHLNWKEALKVVRAGRAVANPNAGFQSQLQEFEQF
.|   .... |||. ||. |  |.|| |.. .|.|||. 
lmlllgvsleealelvrsqrpgavpnpgqlrflyefele
subfamily_DSP3_pd Subfamily DSP3 4-140 2.9e-30 99.0 In-house 10-155 (162) alignment 
Range on Protein: 4-140
Range on HMM: 10-155/162.0
GMNKVLPGLYVGNYRDSKDHAQLERFKISHIIAIHDSpRR--------LLP--DKHYLCVMASDTPDQNLSQYFSVCNDFIHAARLR-EGNVLIHCLAGM
 .. | |.||||.   .||. .|... | |..   .. |              . .|| . ..|.|  .||.||.   .||..|  . || ||.|| .|.
evdevypklyvgdeavakdkskLkklGithvlnaaeg.rfskvdtgaefykdleikylGlevdDvpefdlskyFetaakfidealsqkegkvlvhcvvGv

SRSVTVAVAYIMTATHLNWKEALKVVRAGRAVAnPNAGFQSQLQEFEQ
||| |...||.|   ... .||.. ||. |..  || ||  ||.|...
sRsatlvlayLmirrkmtlveairtvrkkReil.PneGFlkqLaelde
subfamily_DSP8_pd Subfamily DSP8 4-140 4.6e-29 95.0 In-house 14-152 (159) alignment 
Range on Protein: 4-140
Range on HMM: 14-152/159.0
GMNKVLPGLYVGNYRDSKDHAQLERFKISHIIAIHDS--PRRLLPDKHYLCVMASDTPDQNLSQYFSVCNDFIHAARLREGNVLIHCLAGMSRSVTVAVA
|....|. ||.|  .|. ..  |..  ||... .  |      |.....| |   |. | .|...|    .||  |.  .|.||.|.|||.||| |||.|
gptrilknlylGsqkdvlseellsklgisyvlnasnscpkleelkeskflrvPvkDkydekllpwfdksvefidkaksengrvlvhvlaGisrsatvaia

YIMTATHLNWKEALKVVRAGRAVANPNAGFQSQLQEFEQ
|||   ...  || . |.  |.. .||  |. || |.|.
yimktlemsldeayrfvkekrptispnlnflgqLleyek
0041856 (Phosphotyrosine protein) phosphatases II 4-144 1.6e-28 94.9 In-house 18-174 (182) alignment 
Range on Protein: 4-144
Range on HMM: 18-174/182.0
GMNKVLPGLYVGNYRD--------------SKDHAQLERFKISHIIAIHdsPRRLLPDK------HYLCVMASDTPDQNlsqyFSVCNDFIHAARLREGN
........||.|....               ..  .| . .|..|. .   ...  |..      .||..   | .  .    .. ..|||.... ..|.
dldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlt..eelywpellerlgiqylylpwpDhgvpd....ldelldfieevleeggp

VLIHCLAGMSRSVTVAVAYIMTATHLNWKEALKVVRAGRA--VANPNAGFQSQLQEFEQFKLS
||.|| ||..|. |...||.|   .... ||.| ||  |   | .|| .|  ||...| ..|.
vlVHCsaGvgRtgtlvaaylmkklgvsleeavklvrsrRpgmvitpnqyfflqlallellllk
subfamily_STYX_pd Subfamily STYX 4-145 2.3e-24 79.4 In-house 11-160 (166) alignment 
Range on Protein: 4-145
Range on HMM: 11-160/166.0
GMNKVLPGLYVGNYRDSKD--HAQLERFKISHIIAIHDSPRRL-----LPD-KHYLCVMASDTPDQNLSQYFSVCNDFIHAARLREGNVLIHCLAGMSRS
 |...||||..| |  ..     .|..  |.||. | ...        .||  .|| .  .|.. .|. .|.    .||  .  . |.||.|  ||.|||
emqeilpglflgpysaamksklevlkkhgithivcirqnieanlikpnfpdrfrylvldvadntveniirylptvkefiddslqkggkvlvhgnagisrs

VTVAVAYIMTATHLNWKEALKVVRAGRAVANPNAGFQSQLQEFEQFKLSE
 .. .|||| .  |...|| . |.  |   |||.|| |||.|.|   |..
aalviayimetyglkyreafayvqerrfcinpnegfvsqlkeyeaiylak
subfamily_DSP12_pd Subfamily DSP12 5-144 5.3e-37 121.6 In-house 2-145 (155) alignment 
Range on Protein: 5-144
Range on HMM: 2-145/155.0
MNKVLPGLYVGNYRDSKDHAQLERFKISHIIAIHDSPR---RLLPDKHY-LCVMASDTPDQNLSQYFSVCNDFIHAARLREGNVLIHCLAGMSRSVTVAV
....|||||.|. .. .....|. .||.|....   .    .| . | . . . . |.|.... ...  ..|||. |. .||.||.|| ||.|||||. .
vsrilpglylggleavqeeellkelkithvlsvikeelpehklkkgkvstkfiqilDepeediLshldeavdFieealeeegavlvHCqagvSRSvtivi

AYIMTATHLNWKEALKVVRAGRAVANPNAGFQSQLQEFEQFKLS
||.|  ..|. ..|||.|.. .  ..||.||..||. ||. . .
AYlmkkeklslekAlklvkekkpeiepNegFleQLklfekmgck
PTPc_motif_SM00404 5-140 2.6e-36 119.6 In-house 2-139 (140) alignment 
Range on Protein: 5-140
Range on HMM: 2-139/140.0
MNKVLPGLYVGNYRDSKDHAQLERFKISHIIAIHDSPR--RLLPDKHYLCVMASDTPDQNLSQYFSVCNDFIHAARLREGNVLIHCLAGMSRSVTVAVAY
....||.||.|....... |.|. ..|.|.| . .. .  .  .....|..  .|.  ..||.|.. ..|||..|. ..|.||.|| ||.|||.|...||
psrilphlylgskskaqnpallkklgithvinvteevsltkensgfqilqiplddnekdklskyldkvldfienaekkggkvlVHCqaGvSRSatliiaY

IMTATHLNWKEALKVVRAGRAVANPNAGFQSQLQEFEQ
.|.  .|...||...|.  |   .||..|  ||.|.|.
lmryrqlslaeayefvkerRpiispnlnfvrqLieyek
subfamily_DSP10_pd Subfamily DSP10 5-140 3.8e-36 118.4 In-house 14-151 (159) alignment 
Range on Protein: 5-140
Range on HMM: 14-151/159.0
MNKVLPGLYVGNYRDSKDHAQLERFKISHIIAIH-DSPRRLLP-DKHYLCVMASDTPDQNLSQYFSVCNDFIHAARLREGNVLIHCLAGMSRSVTVAVAY
. .||| |..|. .|..|.. |.|..|.... .  ..|      . .|  . .|||  |||.||| .  .||. || .. .||.|| ||.|||.||..||
asqvlpfLflGsekdaadldaldrlnitavlnvttsvPnefeeealkYkripvsDtskqnlkqyfeealefieearkkgsrvLvhCqaGisrsatvviaY

IMTATHLNWKEALKVVRAGRAVANPNAGFQSQLQEFEQ
.|. ..|. ..| | |.  |..  || .|  || |||.
lmkhlnlslndaykfvkekrpiisPnLnfmGqLlefek
0043147 (Phosphotyrosine protein) phosphatases II 5-143 8.6e-30 99.1 In-house 19-161 (172) alignment 
Range on Protein: 5-143
Range on HMM: 19-161/172.0
MNKVLPGLYVGNYRDSKDHAQLERFKISHIIAIHD----SPRRLLPDKHYLCVMASDTPDQnLSQYFSVCNDFIHA--ARLREGNVLIHCLAGMSRSVTV
............. .... ..| . .|.||. . .     .     . .||..   | . . |....  . .||.   |. ..| ||.|| ||..|..|.
pdrfiatqgplrntladfwrmlkelgithivnltellydpellerlgiqylylpwpDhgvp.llellleflefidellalspggpvlVHCsaGvgRtgtl

AVAYIMTaTHLNWKEALKVVRAGRAVANPNAGFQSQLQEFEQFKL
..||.|   .|.. ||.. ||. |  | .| ... .|..||.. |
vaaylml.lglsleeavalvrekRpgavqnpsqyrflyyfeklll
0049260 (Phosphotyrosine protein) phosphatases II 5-140 3.4e-26 87.2 In-house 8-147 (152) alignment 
Range on Protein: 5-140
Range on HMM: 8-147/152.0
MNKVLPGLYVGNYRDSKDHAQLERFKISHIIAIHDSPRR----LLPDKHYLCVMASDTPDQNLSQYFSVCNDFIHA-ARLREGNVLIHCLAGMSRSVTVA
..........|..  ...  .| . .|..|. . .   .         .||..   | . ..|||..  ...||.  |. ..|.||.|| ||..|. |..
pfefiatqgpgpntladfwrmlkelgittivmltellelgklkceqyiqylhlpwpDhgvpdlsqlllflllfieklaldkggpvlVHCsaGvgRtgtlv

VAYIMTaTHLNWKEALKVVRAGRAVANPNAGFQSQLQEFEQ
.||.|   .....||.. ||. | .|.|| |.  .|.|||.
aaylml.lgvsleeavalvrekRpgavpnpgqlrflyefek
0037934 (Phosphotyrosine protein) phosphatases II 5-141 1.4e-25 85.7 In-house 39-240 (243) alignment 
Range on Protein: 5-141
Range on HMM: 39-240/243.0
MNKVLPGLYVGNY--------RDSKDHAQLERFKISHIIAI------------------------------------------------HDSPRRLLPDK
. .|.|.|.....        .. ..   | . .|..|. .                                                .| . ||    
liyvtprliatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqywpgevtygdftvtllseehlddytvrtlllenldlddltrlvihy

HYLCVMASDTPD--QNLSQYFSVCNDFIHA-----ARLREGNVLIHCLAGMSRSVTVAVAYIMTAT-HLNWKEALKVVRAGRAV-ANPNAGFQSQLQEFE
|||..   ..||  ..| .... ...||..     |. ..| ||.|| || .|. |...||.|    .... ||.| .|. |   | .. ..  .|.|..
hylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgRtGtliaaylmllllgvdleeavkllreqRpgkavqtpsqyrflyeal

QF
..
le
0045098 (Phosphotyrosine protein) phosphatases II 5-143 3.2e-24 81.2 In-house 22-272 (278) alignment 
Range on Protein: 5-143
Range on HMM: 22-272/278.0
MNKVLPGLYVGNYR-----------------------------------------DSKDHAQLERFKISHIIAI--------------------------
.....|.||.||.                                           ...  .|   .|..|. .                          
pseitpalylgnldknRykdilpydhsrVkdYINAsyidgypkkfIatqgPlpstvadfwrmlwelgitvivmltelvelgrekcaqywpeggsltygdf

---------------------------HDSPRRLLPDKHYLCVMASDTPDQNLSQYFSVCNDFIHAARL--------------REGNVLIHCLAGMSRSV
                           .| . | .   |||..   ..|.......|  . .||..|.               ..| ||.|| || .|. 
tvtllseevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllsslllldsggpvlVHCsaGvgRtG

TVAVAYIMTAT---HLNWKEALKVVRAGRAV-ANPNAGFQSQLQEFEQFKL
|...||.|      .... ||.| .|  |   | .| ... .| ||..  |
tlvaaylmlelleggvdlleavkelrsqRpglavqnleqyrflyefllell
0051082 (Phosphotyrosine protein) phosphatases II 5-138 1.1e-20 69.2 In-house 8-149 (151) alignment 
Range on Protein: 5-138
Range on HMM: 8-149/151.0
MNKVLPGLYVGNYRDSKDHAQLERFKISHIIAIHDSP-----RRLLPD--KHYLCVMASDTPDQNLSQYFSVCNDFIHAARLR-EGNVLIHCLAGMSRSV
.. | .|||....  . . ..|.. .|..|. . . .      ..||.   ..|..   |.||..|...|  ...|.....   .|.||.|| ||..|. 
fsyvtgglyrsggpladflellkelgiktivnlrseeergycpeylpelgievlhipildwpdpglplsfdavleflellldkkngpvlvHCsaGkgRTG

TVAVAYIMTaTHLNWKEALKVVRAGRA-VANPNAGFQSQLQEF
|....|.|   .... |||. .|. |  | .|| .|. ||...
tlvalylml.lgvsleealeeyrlkrpgvvqpnqqflfqlfal
0036282 (Phosphotyrosine protein) phosphatases II 5-140 1.7e-19 65.6 In-house 12-167 (174) alignment 
Range on Protein: 5-140
Range on HMM: 12-167/174.0
MNKVLPGLYVGNYRDSkDHAQLERFKISHIIAIHDSPRR----------------LLPDKHYLCVMASDTPDQNLSQyFSVCNDFIHAARLR--EGNVLI
.. ..|.|..|..  . . ..| ...|....   ..  .                   . .||...  |    .||. .  . .|.. |...  .| ||.
lsyitprliagqgpla.fwemlkelgittvvmlleekelglykcinywpelredlerlgiqylylpwpDhgvpdlsi.llefvkfveealsedpggpvlV

HCLAGMSRSVTVAVAYIMTATHL-NWKEALKVVRAGR---AVANPNAGFQSQLQEFEQ
|| || .|. |...||.|   .| .  .||..||. |     . .. ..  .|..||.
HCsaGvgRtGtlvaaylmlrglleslvdaldlvrelRlqrpgmvqtpsQyrflyyfek
subfamily_DSP19_pd Subfamily DSP19 6-142 2.3e-37 122.7 In-house 13-150 (152) alignment 
Range on Protein: 6-142
Range on HMM: 13-150/152.0
NKVLPGLYVGNYRDSKDHAQLERFKISHIIAIH-DSPRRLLPDKHYLCVMASDTPDQNLSQYFSVCNDFIHAARLREGNVLIHCLAGMSRSVTVAVAYIM
 .| | ||.|     .|. .|.. || ||. .  . |.    | .||..   |.|...|..|.. . |||. ||  .| ||.|| ||.|||..|..||.|
geveprlylgsqdvaadkeilkekkitHilnvatgvpnvfpkdftylsieilDlpetdllsylkealdFieearskdgavlvHCnAGvSRsasvviaylm

TATHLNWKEALKVVRAGRAVANPNAGFQSQLQEFEQFK
. ..|. .|||..||. |  ..||.||. ||.|.|. .
kkeelsleealelvrearpcikPneGFikqLkeyeael
subfamily_DSP1_pd Subfamily DSP1 6-145 4.7e-33 108.6 In-house 19-159 (163) alignment 
Range on Protein: 6-145
Range on HMM: 19-159/163.0
NKVLPGLYVGNYRDSKDHAQLERFKISHIIAIHDSPRRLLPDK-HYLCVMASDTPDQNLSQYFSVCNDFIHAARLREGNVLIHCLAGMSRSVTVAVAYIM
.|.|. ||.|   .. .  .|.. .|..|. .  .     .|  .| ..  .|.|....|..|.   .||....  .| ||||| ||.||| |. .||.|
ekildfLylGsetvasnleiLkslgitailnvskeldnvfedlfeYkklkleDspkadislvfeeviefidevkkknGkvlihCqaGisRsstlclaylm

TATHLNWKEALKVVRAGRAVANPNAGFQSQLQEFEQFKLSE
. .... .|| . |.  |.. .|||||. || ..|.  | |
ktkrvsleeafdfvkqrRsiisPnagFvlqLlnyekkllle
subfamily_Dicty-DSP19-like_pd Subfamily Dicty-DSP19-like 6-140 1.1e-23 77.3 In-house 4-150 (154) alignment 
Range on Protein: 6-140
Range on HMM: 4-150/154.0
NKVLPGLYVGNYRDSKDHAQLERFKISHIIAIHDSPRRLLPDK----------HYLCVMASDTPDQNLSQYFSVCNDFIHAAR--LREGNVLIHCLAGMS
.|.   ||.. .  . .  .|.  .| .|. .      |..|.          .|| .   | ..... . .. . .||. |   .....||.|. .|.|
skeaiflyissfdaalnkldlqlkniksilnvgiGinnlftdensdindgfiieylnlelfddvnfdiiekldkafefiddaiggvennkvlvhsdkGvs

RSVTVAVAYIMTATHLNWKEALKVVRAGRAVANPNAGFQSQLQEFEQ
|| .....|.|   .... .||....  | . .|| ||  ||. ||.
rsaallisylmdklkislslalellkdsryiikPnqGflkqleifek
0051429 (Phosphotyrosine protein) phosphatases II 6-163 3.3e-18 61.8 In-house 17-244 (272) alignment 
Range on Protein: 6-163
Range on HMM: 17-244/272.0
NKVLPG-LYVGNYR---DSKDHAQLERFKISHIIAIHDSP-------RRLLPDKHYLCVMASDTPDQNLSQYF---------------------------
..|.|| || ...    . .| ..|.. .|..|. . .          |..|. .||..   |. ..  ....                           
rvvkpgrlyrsggplpltaadfwrlkelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseellldyilrellltlllsa

---------------------SVCNDFIHAARLrEGNVLIHCLAGMSRSVTVAVAYIMTaTHLN--------------WKEALKVVRAGRAVANPNAGFQ
                     . . ..... .  .|.||.|| ||..|. ||......    ..              . ||.. .|| |. |... .. 
gearevmhlhytdwpdhgvpqeallellellld.ggpvlvHCsaGkdRTGtvvalllll.lgvsletivddYlltnlyleeaveelraqrpgavqteeqy

SQLQEFEQFKlSEERRRLRERFPSSALEQLD
 .|.|...    ..    |...  .||...|
lflyeallel.lrsllsvraeyllaaldaid
0042113 (Phosphotyrosine protein) phosphatases II 6-141 5e-18 60.9 In-house 48-241 (245) alignment 
Range on Protein: 6-141
Range on HMM: 48-241/245.0
NKVLPGLYVGNYRDSKDHA----QLERFKISHIIAIHD-----------------------------------------------SPRRLLPDKHYLCVM
 .. |.......  ... .    .| . .|..|. . .                                                    . . ||... 
yritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywplgesltygdftvtllseehlddytvrtlevtnlgddesrevihyhylp

ASDTPDQNLSQYFSVCNDFIHAARL--REGNVLIHCLAGMSRSVTVAVAYIM-----TATHLNWKEALKVVRAGRAVANPNAGFQSQLQEFEQF
  | .  .|....  . .|.. |.   ..| ||.|| || .|. |...||.|     .   ... ||.| .|  |  | .. ..  .|.|....
wpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylmleqlekelgvsleeavkelrsqRpgavqtpsqyrflyealle
subfamily_DSP6_pd Subfamily DSP6 7-140 5.9e-33 107.6 In-house 16-152 (158) alignment 
Range on Protein: 7-140
Range on HMM: 16-152/158.0
KVLPGLYVGNYRDSKDHAQLERFKISHIIAIHDS-PRRLL--PDKHYLCVMASDTPDQNLSQYFSVCNDFIHAARLREGNVLIHCLAGMSRSVTVAVAYI
..|| ||.|. .|...   |...||.... .    |      .. .|| . ..|   |||...|    .||  || .. .||.|||||.||||||..||.
eilpllylGsakdasnlevlkklkikyvlnvtsnlpnkfeesgelkylqipiedhlsqnlakffPeaiefidearskkskvlvhClaGisrsvtvtlayl

MTATHLNWKEALKVVRAGRAVANPNAGFQSQLQEFEQ
|  ..|  ..| ..|.. ..   ||  |  || .||.
mkklalslndaydlvkkrksnisPnfnfmgqlldfer
subfamily_LRR-DSP_pd Subfamily LRR-DSP 7-140 4.3e-30 98.7 In-house 122-256 (263) alignment 
Range on Protein: 7-140
Range on HMM: 122-256/263.0
KVLPGLYVGNYRDSKDHAQLERFKISHI-IAIHDSpRRLLPDK-HYLCV-MASDTPDQNLSQYFSVCNDFIHAARlREGNVLIHCLAGMSRSVTVAVAYI
.....|..|    ..... |.   ..|| .|. |  . | |.   || .  . |... ..||.|   | ||.  | ..| ||.|| ||.||| |. ..|.
eiidklflGgldsannksilkdlgvthillavadf.ePlfPklfkylsiddiedvdeadisqhfeetnafieeGr.kkGGvlvhcraGvsrsstlvisyl

MTATHLNWKEALKVVRAGRAVANPNAGFQSQLQEFEQ
|   .|..|||| .|  .|.  .|| ||. ||. .|.
mkkqrlkfkealdlvikkrpriqPnpGfkdqlkkyek
0049772 (Phosphotyrosine protein) phosphatases II 7-140 1e-26 89.8 In-house 149-271 (314) alignment 
Range on Protein: 7-140
Range on HMM: 149-271/314.0
KVLPGLYvgNYRDSKDHAQLErfkishiiAIHDS-PRRLLPDKHYLCVMASDtPDQNLSQYFSVCNDFIHAArLREGNVLIHCLAGMSRSVT-VAVAYIM
  |.|..  |. . .| ..|.         .... ..   .  .||..  .| ....|...|  . .||..|  ..|.||.|| ||..|. | |..||.|
lildgng..neptaadlellk........eelydpelferlgikylripvpD.gsaplledfdeflefieea.dkggpvlvHCkaGkgRtgtfvvaaylm

TATHLNWKEALKVVRAGRAvANPNAGFQSQLQEFEQ
 . .....|||. ||. |  .||| ||  ||...|.
kllgvsleealedvrlkRp.inpnpgfieqleqyef
PTEN_1 7-145 1.2e-26 88.7 In-house 43-194 (196) alignment 
Range on Protein: 7-145
Range on HMM: 43-194/196.0
KVLPGLYVGNYRDS-KDHAQLERFKISHIIAIHDSPRR----------LLPDKHYLCVMASDTPDQNLSQYFSVCNDFIHAARL-R-EGNVLIHCLAGMS
.. .|||.|...|  .|  .|.  .| ...   . .               .  || ..  | . ..||. | .|..||..... . ...||.|| ||..
eideglyrgslkdvaadldnlkedgitlvvnlseeeelsgrsydleeffksgveylhfpieDhgapslselfdicksfiewllsdpngnvVlVHCkaGlg

RSVTVAVAYIMTATHLNWKEALKVVRAGRAVANPNAGFQSQLQEFEQFKLSE
||.||. || | .  |. .|||. ||. | ...|| ..| .|.|...  |.|
RsGtvvaayLmykgkltadeAlelvrekRppgapnspsqerlleyfaellae
subfamily_Slingshot_pd Subfamily Slingshot 7-147 8.4e-24 77.8 In-house 21-162 (169) alignment 
Range on Protein: 7-147
Range on HMM: 21-162/169.0
KVLPGLYVGNYRDSKDHAQLERFKISHIIAIHDSPRRLLPDK-HYLCVMASDTPDQNLSQYFSVCNDFIHAARLREGNVLIHCLAGMSRSVTVAVAYIMT
|.   .|.|   .. .  .|.. ....|. .        |.| .|| .   |.....| .|.    .||..|. .. .||.||  |.||| .. .|| | 
kifdhvylGsewnasnleelkengveyilnvtkeidnffpekfeylnirvydeeetdllkywnetykfiekakkkgskvlvhckmGvsrsastviayamk

ATHLNWKEALKVVRAGRAVANPNAGFQSQLQEFEQFKLSEER
. .|. .|||. |.  | |..||.|| .||.|.|    .. .
eyglsleealeyvkerrsvikPnkgflkqleeyeGileaskq
0040439 (Phosphotyrosine protein) phosphatases II 8-141 2e-22 75.5 In-house 32-244 (249) alignment 
Range on Protein: 8-141
Range on HMM: 32-244/249.0
VLPGLYVGNYRD------------------------SKDHAQLERFKISHIIAIHDSPR-----------------------------------------
.||||. ..| .                        ...  .| . .|..|. . .  .                                         
ilpglflsdyinAsyidgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqywplggsleygdftvtllsvevkddytvrtlel

---RLLPDKHYLCVMASDTPDQNLSQYFSVCNDFIHAARL------REGNVLIHCLAGMSRSVTVAVAYIM-----TATHLNWKEALKVVRAGRAVANPN
      .. ..|..   | ||......|. . |||.|.|       ..| ||.|| ||..|. |...||.|     .  ... .||.| .|  |  | .|
tnlydgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtfiaaylmleqlekelgvdleeavkllrsqRpgavqn

AGFQSQLQEFEQF
 ..  .|.|....
peqyrflyealle
subfamily_STYXL1_pd Subfamily STYXL1 8-143 1.4e-19 63.8 In-house 14-154 (157) alignment 
Range on Protein: 8-143
Range on HMM: 14-154/157.0
VLPG-LYVGNYRDSKDHAQLERFKISHIIAIHDSPRRLL---PD-KHYLCVMASDTPDQNLSQYFSVCNDFIHAARLREGNVLIHCLAGMSRSVTVAVAY
|||| ||.|||..... |  . .|.   . .     .|.   .|  . | .  .|... .| . ..   .||.  . ..  ||.    |.|||..|..||
vlPgklylGnykqaqnpaikkdlkvkahvnvsmdadkliagvadvakllhiavedeneadllerlkeavqfiekhkkegevvlvfsnkGisrsaaviiay

IMTATHLNWKEALKVVRAGRAVANPNAGFQSQLQEFEQFKL
.|   ... |.|.| ..  .   .|| .| .||.|.|.  |
lmyskkitlkkaykylkkCkenvkPnrafveqlseWekqll
0038934 (Phosphotyrosine protein) phosphatases II 10-144 1.8e-15 52.5 In-house 36-178 (194) alignment 
Range on Protein: 10-144
Range on HMM: 36-178/194.0
PGLYVGNYRDSKDHAQLERFKISHIIAIHDSPRR----LLPD--KHYLCVMASD----TPDQNLSQYFSVCNDFIhaARLREGNVLIHCLAGMSRSVTVA
..||. ...|  .  .|   |. ..| .. . |     ....   .||  .  |     ....| ........|.  ..  .| |..|| ||..|. |..
eelyrfspedlvrylkllnvklglvidltnteryYdpeefekagieylklpfpddgtvPsleillrfldlvdefl..nedpggvvaVHCkaGlgRtGtlv

VAYIMTATHLNWKEALKVVRAGRAVANPNAGFQSQLQEFEQFKLS
.||..   ... .||.. .|  |  | || .. ..|... ..  .
aaYLiyrlgmsaeeAialfrekRpgaipnqdyleallkrykelrk
DSPc Dual specificity phosphatase, catalytic domain 12-140 3.6e-33 109.3 Pfam-A 1-132 (133) alignment 
Range on Protein: 12-140
Range on HMM: 1-132/133.0
LYVGNYRDSKdHAQLERFKISHIIAIHDSPR----RLLPDKHYLCVMASDTPDQNLSQYFSVCNDFIHAARLREGNVLIHCLAGMSRSVTVAVAYIMTAT
||.|.. ...  |.|| ..|...| . .. .    .  ....||..   |. ....|.... . .||..|. ....||.|| ||.||| |...||.|.  
lylgskstas.lalleklgitlvinvtkevpnnnaikkseieylripvedetetkiskeleeavefiekaeqkgkkvlVHCqaGisRSatliiaYlmktk

HLNWKEALKVVRAGRAVANPNAGFQSQLQEFEQ
.|. .||...|.  |   .|||||. || |.|.
nlslneAyefvkerrskispnagflrqLleyer
DSPc Dual specificity phosphatase, catalytic domain 12-140 3.6e-33 109.3 In-house 1-132 (133) alignment 
Range on Protein: 12-140
Range on HMM: 1-132/133.0
LYVGNYRDSKdHAQLERFKISHIIAIHDSPR----RLLPDKHYLCVMASDTPDQNLSQYFSVCNDFIHAARLREGNVLIHCLAGMSRSVTVAVAYIMTAT
||.|.. ...  |.|| ..|...| . .. .    .  ....||..   |. ....|.... . .||..|. ....||.|| ||.||| |...||.|.  
lylgskstas.lalleklgitlvinvtkevpnnnaikkseieylripvedetetkiskeleeavefiekaeqkgkkvlVHCqaGisRSatliiaYlmktk

HLNWKEALKVVRAGRAVANPNAGFQSQLQEFEQ
.|. .||...|.  |   .|||||. || |.|.
nlslneAyefvkerrskispnagflrqLleyer
subfamily_MKPLT_pd Subfamily MKPLT 12-143 8.7e-25 81.1 In-house 29-161 (164) alignment 
Range on Protein: 12-143
Range on HMM: 29-161/164.0
LYVGNYRDSKDHAQLERFKISHIIAIHDSPRRLLPDK-HYLCVMASDTPDQNLSQYFSVCNDFIHAARLREGNVLIHCLAGMSRSVTVAVAYIMTATHLN
|| ||  .....  |.  || ||. .    .   |    || |  .|..|..||...   ..|.  |    | ||.||  | ||| .|.||....     
lylGnakhatnekvlkdlkithivnvsqekkdafpksveYlqvkvedesdeqlssfleraakfladaidsGGrvlvhcvqGksrsssvtvafLikskgwt

WKEALKVVRAGRAVANPNAGFQSQLQEFEQFKL
 ||| . ..  |....|| ||  || .||.. |
lkeayeylkerrsivapnrGflkqlakfeelil
subfamily_MKPLV_pd Subfamily MKPLV 12-143 8.7e-25 81.1 In-house 29-161 (164) alignment 
Range on Protein: 12-143
Range on HMM: 29-161/164.0
LYVGNYRDSKDHAQLERFKISHIIAIHDSPRRLLPDK-HYLCVMASDTPDQNLSQYFSVCNDFIHAARLREGNVLIHCLAGMSRSVTVAVAYIMTATHLN
|| ||  .....  |.  || ||. .    .   |    || |  .|..|..||...   ..|.  |    | ||.||  | ||| .|.||....     
lylGnakhatnekvlkdlkithivnvsqekkdafpksveYlqvkvedesdeqlssfleraakfladaidsGGrvlvhcvqGksrsssvtvafLikskgwt

WKEALKVVRAGRAVANPNAGFQSQLQEFEQFKL
 ||| . ..  |....|| ||  || .||.. |
lkeayeylkerrsivapnrGflkqlakfeelil
subfamily_Choan-DSP_MKP-1_pd Subfamily Choan-DSP_MKP-1 12-141 7.6e-23 74.7 In-house 15-146 (148) alignment 
Range on Protein: 12-141
Range on HMM: 15-146/148.0
LYVGNYRDSKDHAQLERFKISHIIAIHDSPRRLLPDK--HYLCVMASDTPDQNLSQYFSVCNDFIHAARLREGNVLIHCLAGMSRSVTVAVAYIMTATHL
|..|. .   |  .|. . ...|.    . .  | ..  .|| |  .| |...||..|    .|.. |. . . ||.|.  |.|||  .|.....   . 
LFlGskksaadlealkalgvtrivnatkerdnaldqrgieYlhvaldDkpkedlsaiFediiafvrkakdeGrrvLvhlqmGvsrssalallwlidfkrv

NWKEALKVVRAGRAVANPNAGFQSQLQEFEQF
  |||| .|.  |   .|| || .||.|.|| 
slkealalvkskrryvdpnlgfLkqLaeleqa
subfamily_Sponge-DSP-Subfam1_pd Subfamily Sponge-DSP-Subfam1 12-140 6.2e-19 61.5 In-house 6-139 (145) alignment 
Range on Protein: 12-140
Range on HMM: 6-139/145.0
LYVGNYRDSKDHAQLERFKISHIIAIHDS-----PRRLLPDKHYLCVMASDTPDQNLSQYFSVCNDFIHAARLREGNVLIHCLAGMSRSVTVAVAYIMTA
||||    ..| . |. . || |. .  .           . . | . |.|    .|||.|    |||   .     |..||.||.||||||.||..|  
lyvgsalhandvptlqelgisrivnmaagslvasqelksesieillitaedlesydlsqhfdevtdfidkgkeegagvfvhcmagvsrsvtvsvaflmky

THLNWKEALKVVRAGRAVANPNAGFQSQLQEFEQ
  .   || . ||. |  | ||  |  .| ..|.
cnmtlseaarqvrsnrllaypnvtflknllnlek
0045450 (Phosphotyrosine protein) phosphatases II 24-141 2.1e-22 75.7 In-house 125-302 (307) alignment 
Range on Protein: 24-141
Range on HMM: 125-302/307.0
AQLERFKISHIIAIHDSPRR-----------------------------LLPDKHYLCVMASDT-----------------PDQNLSQYFSVCNDFIHAA
 .| . ....|. . ..  .                              |.. .....  .|.                 ||......|. . |||...
rmlweqgvtvivmltelvelgrekcaqywPdegeeltygnftvtllseehldgytvrtlevtdldgtgesrtvthfhytgwpdhgvppsfeelldfieev

RL------REGNVLIHCLAGMSRSVTVAVAYIMTATH--------LNWKEALKVVRAGRAVANPNAGFQSQLQEFEQF
|       ..| ||.|| ||..|. |...||.|   .        ... ||.| .|. |  | .| ..  .|.|....
rkaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrflyealle
0040438 (Phosphotyrosine protein) phosphatases II 29-143 3.3e-20 68.0 In-house 109-276 (317) alignment 
Range on Protein: 29-143
Range on HMM: 109-276/317.0
FKISHIIAIHDSPRR----------------------------LLPDKHYLCVMASDT----------------PDQNLSQYFSVCNDFIHAARLR----
 ....|. . ..  .                             |.. ...... .|.                ||... .... . ||..|.|      
qgvtvivmLteleelgrekcaqYwplgetltygdftvtllseeelagitlrtlevedlgdsesrtvthfhytgWpdhgvppspdllldfleavrealedp

EGNVLIHCLAGMSRSVTVAVAYIM-----TATHLNWKEALKVVRAGRAVANPNAGFQSQLQEFEQFKL
.| ||.|| || .|. |...||.|     .  .....||.| .|. |. | .. ..  .| ..... |
ggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrflydalleyl
0039614 (Phosphotyrosine protein) phosphatases II 29-143 3e-17 58.5 In-house 169-289 (297) alignment 
Range on Protein: 29-143
Range on HMM: 169-289/297.0
FKISHIIAIHDSPRrllpdKHYLCVMASDTPDQNLSQYFSVCNDFIHAARL------REGNVLIHCLAGMSRSVTVAVAYIM-----TATHLNWKEALKV
... ..   ....      ... ..   . || .  ...... .|....|       ..| ||.|| || .|. |...||.|     .  .....||.| 
ytvrtlevtnnges.....rtvthfqytgwpdhgvppslellleflelvrealaelpkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavke

VRAGRAVANPNAGFQSQLQEFEQFKL
.|  |  | .. ..  .|...... |
lreqRpgavqtpsqyrflydallell
0043336 (Phosphotyrosine protein) phosphatases II 30-140 6.9e-16 54.0 In-house 163-274 (278) alignment 
Range on Protein: 30-140
Range on HMM: 163-274/278.0
KISHiiaIHDSPRRLLPDKHYLCVMASDTPDqNLSQYFSVCNDFIHAARLREGNVLIHCLAGMSRSVTVAVAYIM-----TATHLNWKEALKVVRAGRAV
....     |.. |     |||...  ..|. .||.... ......| . ..| ||.|| || .|. |....|..     .  ...  ||.| .|  |. 
evtn...lgdgesrtvthyhylgwpdhgvpe.slsllldflkavrealedsngpvlVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqRpg

ANPNAGFQSQLQEFEQ
| ..  .  .| |...
avqtpsqyrflyeall
subfamily_RNGTT_pd Subfamily RNGTT 53-123 7.5e-06 19.7 In-house 86-155 (189) alignment 
Range on Protein: 53-123
Range on HMM: 86-155/189.0
VMASDTPDQN-LSQYFSVCNDFIHaaRLREGNVLIHCLAGMSRSVTVAVAYIMTATHLNWKEALKVVRAGRA
    ..|...  ... .....|..  .  |  . .||  |  |.  ..|.|..  .. . ..|... .  | 
agkgeaPeaeqvkefiklveeffk..knpeevigvhCthGfnRtGFlivsyLvekedwsveaavalFakaRp
0047943 (Phosphotyrosine protein) phosphatases II 55-135 3.4e-13 45.1 In-house 173-264 (273) alignment 
Range on Protein: 55-135
Range on HMM: 173-264/273.0
ASDTPDQNLSQYFSVCNDFIHAARL------REGNVLIHCLAGMSRSVTVAVAYIM-----TATHLNWKEALKVVRAGRAVANPNAGFQSQL
  . ||..  .... . .||...|       ..| |..|| || .|. |.......     .   .. .||.| .|  |  . ..  .  .|
ytgwpdhgvppslesllefielvrkalealpsngpvvVHCsaGvgRtgtfialdllldqlekeggvdvleavkllrsqRpgmvqtpeqyrfl
0036941 (Phosphotyrosine protein) phosphatases II 56-143 9e-17 56.8 In-house 176-277 (297) alignment 
Range on Protein: 56-143
Range on HMM: 176-277/297.0
SDTPDQNLSQYFSVCNDFIHAARL------REGNVLIHCLAGMSRSVTVAVAYIM--------TATHLNWKEALKVVRAGRAVANPNAGFQSQLQEFEQF
 . || .. .... . |||...|       ..| ||.|| || .|| |...|..|        .   .. .||.| .|  |. | .. ..  .| |....
tgwpdhgvpespaslldfielvrkvlkllpsggpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyealle

KL
 |
ll
0051299 (Phosphotyrosine protein) phosphatases II 56-128 4.3e-12 41.5 In-house 190-271 (288) alignment 
Range on Protein: 56-128
Range on HMM: 190-271/288.0
SDTPDQNLSQYFSVCNDFIHAARLR----EGNVLIHCLAGMSRSVTVAVAYIM-----TATHLNWKEALKVVRAGRAVANPN
 . ||..  .... . ||....|      .| |..|| || .|. |.......     .  .... ||.| .|  |  . ..
tnwpdhgvpdspellldflrlvrkalasgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlreqRpgmvqt
0050432 (Phosphotyrosine protein) phosphatases II 56-127 7e-12 40.7 In-house 205-283 (308) alignment 
Range on Protein: 56-127
Range on HMM: 205-283/308.0
SDTPDQNLSQYFSVCNDFIHAARLR--EGNVLIHCLAGMSRSVTVAVAYIM-----TATHLNWKEALKVVRAGRAVANP
 . ||..  .... . ||....| .  .|....|| || .|. |.......     .  .... ||.| .|  |. . .
tnWpdhgvPpspeilldflelvrkslpggpivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkklReqRpgmvq
0046845 (Phosphotyrosine protein) phosphatases II 56-125 1.6e-10 36.3 In-house 173-256 (284) alignment 
Range on Protein: 56-125
Range on HMM: 173-256/284.0
SDTPDQNLSQYFSVCNDFIHAARLR------EGNVLIHCLAGMSRSVTVAVAYIMTAT--------HLNWKEALKVVRAGRAVA
 . ||..  ....   .|....|        .| ...|| ||..|. |.......           ...  ||.| .|  |  .
tswpdhgvppspedlleflrlvrellenlpgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgm
0048567 (Phosphotyrosine protein) phosphatases II 59-132 1.3e-07 26.1 In-house 52-130 (157) alignment 
Range on Protein: 59-132
Range on HMM: 52-130/157.0
PDQNLSQYFSVCNDFIHAARLREGNVLIHCLAGM---SRSVTVAVAYIMTATHLNWKEALKVVRAGR--AVANPNAGFQ
.   | ... . |.|..  .|... . .|| ||.   .|..|.. .|..   ...  ||.. .|  |   |  . |.. 
nlailyrFilklnkflkilelagkaiavhckaglkkrgrtatLigcYlilhlgftpeeaiaplrivrpgsvpfrdasyl
PTPc_DSPc_SM00012 59-117 3.2e-07 25.9 In-house 16-75 (105) alignment 
Range on Protein: 59-117
Range on HMM: 16-75/105.0
PD--QNLSQYFSVCNDFIHAARLrEGNVLIHCLAGMSRSVTVAVAYIMTATHLNWKEALKV
|.  ... ...  .... ...   ...|..|| || .|. |.....|.   . .... ...
Peesdsilellravkknknkses.skpvvVhCsaGvgRtgtfvaldillqqleketkevdi
subfamily_MSG5_pd Subfamily MSG5 63-140 5.2e-13 42.4 In-house 81-158 (165) alignment 
Range on Protein: 63-140
Range on HMM: 81-158/165.0
LSQYFSVCNDFIHAARLREGNVLIHCLAGMSRSVTVAVAYIMTATHLNWKEALKVVRAGRAVANPNAGFQSQLQEFEQ
. . .|     ||||. ..  .|.||  |.||| .. |||||    |  ..| . ...     .|. |.  || |.| 
ivkdlsrltriihaatskrkkilvhcqcglsrsaslivayimkyynlslrdaydklksvaddispsiglifqlmewev
subfamily_PTPMT1_pd Subfamily PTPMT1 67-143 1.1e-12 42.7 In-house 93-169 (171) alignment 
Range on Protein: 67-143
Range on HMM: 93-169/171.0
FSVCNDFIHAARLREGNVLIHCLAGMSRSVTVAVAYIMTATHLNWKEALKVVRAGRAVANPNAGFQSQLQEFEQFKL
 .   .||.  . .   | .|| || .|| |.. .|.|. ..|. .||||.... |   . .   ...|||.|.. |
lekgvefiekvaskgkrvYvHCkaGrgRsatlvacylmkkeklspeeAlkalkkkRkiirlakkqwkalqeyeekll
subfamily_CDC14_pd Subfamily CDC14 69-122 5.2e-07 23.8 In-house 251-304 (328) alignment 
Range on Protein: 69-122
Range on HMM: 251-304/328.0
VCNDFIHAARLREGNVLIHCLAGMSRSVTVAVAYIMTATHLNWKEALKVVRAGR
. . |...|   ||.. .|| ||. |  |.  .|.|   ... .||.  .|  |
ivkkfleiaekaeGaiavhCkaGLGrtGtLiacylmkhyrftaaeaiawlricr
subfamily_PTPDC1_pd Subfamily PTPDC1 76-143 7.8e-08 27.0 In-house 109-176 (182) alignment 
Range on Protein: 76-143
Range on HMM: 109-176/182.0
AARLREGNVLIHCLAGMSRSVTVAVAYIMTATHLNWKEALKVVRAGRAVANPNAGFQSQLQEFEQFKL
|  |.||.| .|| ||. |   .  .|.. |..|. ..|.|.||. |. .    .    ..||..| .
afalqegkvavhChaGlGrtGvliacylvyakrltaekaiklvrskrpksiqtreqvelvkefalfli