Gene Plip in Drosophila melanogaster

Synonym: 150466_at, CG10371, Dmel\CG10371, PLIP, plip, Dmel_CG10371, Plip

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family DSP
Subfamily PTPMT1
Protein sequence
ID Type Fasta BLAST phosphatome Note
DmelP024_AA protein Get Run
DmelP024_AA_29-194 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
0045098 (Phosphotyrosine protein) phosphatases II 7-192 5.2e-30 100.2 In-house 14-268 (278) alignment
Range on Protein: 7-192
Range on HMM: 14-268/278.0
MFARVSFYPTLLYNVLMEKASARNWYDRI--------------------DEHVILGALPFRSQANDL---IEKENMKAVVSMNEDYEL------------
 | .. ..|   .. |...  ..|.|  |                    . . |. . |. | ..|    . ... ...|...| .||            
efllllgipseitpalylgnldknRykdilpydhsrVkdYINAsyidgypkkfIatqgPlpstvadfwrmlwelgitvivmltelvelgrekcaqywpeg

----------------------------TAFSNNTEKWRKLGIEFLQLATTDIFESPNQE---KLFRGVEFINKFLPLKQRIGGLSSSYQPENvGSVYVH
                            | .... | . ..|.. |.. . . ...|...    ... .|||...| | ..  ..| ...... | |.||
gsltygdftvtllseevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllsslllldsg.gpvlVH

CKAGRTRSATLVGCYLMMKN---GWTPDQAVDHMRKCRPH-ILLHTKQWDALRLFY
|.||  |..|||..|||...   |.....||...|..||. .. .  |.  |  | 
CsaGvgRtGtlvaaylmlelleggvdlleavkelrsqRpglavqnleqyrflyefl

subfamily_PTPMT1_pd Subfamily PTPMT1 13-196 9.4e-80 261.0 In-house 1-169 (171) alignment
Range on Protein: 13-196
Range on HMM: 1-169/171.0
FYPTLLYNVLMEKASARNWYDRIDEHVILGALPFRSQANDLIEKENMKAVVSMNEDYELTAFSNNTEKWRKLGIEFLQLATTDIFESPNQEKLFRGVEFI
||||||||||.||||.||||||||..||||||||||....||||||.|||||.||.|||.|..|.||.|.|||.|.|||||.|..|.|..|||..|||||
fyPtllynvlvekaskrnwydriDdtvilGalPfrslikeLiekenvkavvslneeyelkalansteewkklgveqlqlatvDfteapdleklekgvefi

NKFLPLKQRIgglsssyqpenvgsvYVHCKAGRTRSATLVGCYLMMKNGWTPDQAVDHMRKCRPHILLHTKQWDALRLFYTNNV
.|.  ...|.               ||||||||.||||||.||||.|. ..|..|.....|.|..|.|..|||.||. ......
ekvaskgkrv...............YvHCkaGrgRsatlvacylmkkeklspeeAlkalkkkRkiirlakkqwkalqeyeekll

0044763 (Phosphotyrosine protein) phosphatases II 13-193 2.9e-36 120.1 In-house 4-168 (178) alignment
Range on Protein: 13-193
Range on HMM: 4-168/178.0
FYPTLLYNVLMEKASARNWYDRIDEHVILGALPFrSQANDLIEKENMKAVVSMNEDYELTAFSNNTEKWRKLGIEFLQLATTDIFESPNQEKLFRGVEFI
... ||.|. .. .|  .....|.....||.||  ..  .|. ... ...|...|..||  .... . ... ||..|.. . |  . .  | ... ||||
rtrvllsnleglersdyinaseilpglylgslpp.addlellkelgithivnlteelelgflkcdpywpeeagiqylhipipDhgvpdllehflefvefi

NKFLplkqrigglsssyQPENvGSVYVHCKAGRTRSATLVGCYLMMKNGWTPDQAVDHMRKCRPhILLHTKQWDALRLFYT
...|             .... | |.|||.||. ||.||| .|||.|.|.....|....|..|| |  .  |.  |..|. 
eeal.............dekg.gpvlVHCsaGvgRsgtlvaaylmkklglsleeaielvrerRp.ivpnpgqlrqLyefel

PTEN_1 14-192 5.8e-28 93.0 In-house 15-188 (196) alignment
Range on Protein: 14-192
Range on HMM: 15-188/196.0
YPTLLYNVL--------MEKASARNWYDRIDEHVILGALPFRSQANDLIEKENMKAVVSMNEDYELTAFSNNTEKWRKLGIEFLQLATTDiFESPNQEKL
.||.|...         | ||..|. ...|||....| |.. ..  |  ....  .||...|..|| ..| . |...| |.|.|..  .| .  |. ..|
lptelldltyitsriiamgkapsrpllqeideglyrgslkdvaadldnlkedgitlvvnlseeeelsgrsydleeffksgveylhfpieD.hgapslsel

FRGVEFINKFLPLKQRigglsssyqpenVGSVYVHCKAGRTRSATLVGCYLMMKNGWTPDQAVDHMRKCRPHILLHTKQWDALRLFY
|. .. .   | ....             . |.||||||..||.|.| .||| |...|.|.|....|..||.. ... .. .|. ..
fdicksfiewllsdpn............gnvVlVHCkaGlgRsGtvvaayLmykgkltadeAlelvrekRppgapnspsqerlleyf

0046846 (Phosphotyrosine protein) phosphatases II 27-193 2.4e-31 104.2 In-house 7-170 (176) alignment
Range on Protein: 27-193
Range on HMM: 7-170/176.0
SARNWYDRIDEHVILGALPFRSQAN---------DLIEKENMKAVVSMNEDYELTAF--SNNTEKWRKLGIEFLQLATTDIFESPNqEKLFRGVEFINKF
  ....|.|....|||..|   |..         ... ... .|||...|..||  .   |  . ..||||..|.| . |    .  | |.. .|||...
gldldldyinanlilgsrpiatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpeleklgiqylhlpwpDhgvpdl.elllellefirea

LplkqrigglsssyqPENvGSVYVHCKAGRTRSATLVGCYLMMK-NGWTPDQAVDHMRKCRP-HILLHTKQWDALRLFYT
|               |. | |.|||.||. |..||| .||... .|.....|....|..|| ... . .|.  |. |. 
l..............keg.gpvlVHCsaGigRtgtlvaayllelekglsveealalvreqRplgavqtpeQyrflyefel

0041856 (Phosphotyrosine protein) phosphatases II 28-192 3.8e-26 87.2 In-house 17-167 (182) alignment
Range on Protein: 28-192
Range on HMM: 17-167/182.0
ArnWYDRIDEHVILGALPFR-------------SQANDLIEKENMKAVVSMNedyeltAFSNNTEKWRKLGIEFLQLATTDIFESPnqekLFRGVEFINK
   ..|.| ....||.||..              .  ... ... ...|...       .  . |.. .|||..|.|   |    .    |   ..||..
r..dldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlt......eelywpellerlgiqylylpwpDhgvpd....ldelldfiee

FLPlkqrigglsssyqpeNVGSVYVHCKAGRTRSATLVGCYLMMKNGWTPDQAVDHMRKCRPHILLHTKQWDALRLFY
 |                . | |.|||.||. |..|||..|||.|.|.....||...|..||..  .  |.  |.|..
vle...............eggpvlVHCsaGvgRtgtlvaaylmkklgvsleeavklvrsrRpgmvitpnqyfflqlal

0039614 (Phosphotyrosine protein) phosphatases II 28-191 8.9e-22 73.3 In-house 92-284 (297) alignment
Range on Protein: 28-191
Range on HMM: 92-284/297.0
ARNWYDRIDEHVILGALPFRSQAN---DLIEKENMKAVVSMNEDYELT-----AFSNNTEKWRKLGIEFLQLATTDIFE---------------------
  . ||... ..|.   |  .  .    .. ... ...|....  ||       ........ .. ...|.  . | .                      
yvdgydlltrkfIatqgPlpetvedFwrmvweqgvtvivmLtklvelgrkcaqywpeeggtygdftvtllkvehldgytvrtlevtnngesrtvthfqyt

------SP-NQEKLFRGVEFINKFLPLKqrigglsssyqpENVGSVYVHCKAGRTRSATLVGCYLM-----MKNGWTPDQAVDHMRKCRPHILLHTKQWD
       | . | |.. .|.....|               .. | |.|||.||  |..|....|||      . |.....||...|..||..     |. 
gwpdhgvppslellleflelvrealael............pkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavqtpsqyr

ALRLF
 |. .
flyda

0042113 (Phosphotyrosine protein) phosphatases II 29-191 4.9e-25 83.8 In-house 12-238 (245) alignment
Range on Protein: 29-191
Range on HMM: 12-238/245.0
RNWY--------------------------------DRIDEHVILGALPFRSQAND---LIEKENMKAVVSMNEDYELTA--------------------
.|.|                                .|| ...|... | ..  .|   .. ... ...|...|. ||                      
knrysdilpydhtrvklspdggdldsdyinasyvdgyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywplgesltygdftv

-----------------FSNNTEKWRKLGIEFLQLATTDIFESPNQEKLFRGVEFINKFLPLkqrigglsssyqPENvGSVYVHCKAGRTRSATLVGCYL
                  .|. ... . .| ...|   |  . .. | |.. .||..|.|              ..| | |.|||.||. |..|....||
tllseehlddytvrtlevtnlgddesrevihyhylpwpdhgvpdllellldflefvrkalae............dsn.gpvlVHCsaGvgRtGtfiaayl

M-----MKNGWTPDQAVDHMRKCRPHILLHTKQWDALRLF
|        |.....||...|..||..     |.  |. .
mleqlekelgvsleeavkelrsqRpgavqtpsqyrflyea

0048179 (Phosphotyrosine protein) phosphatases II 30-192 4.8e-29 96.3 In-house 2-141 (144) alignment
Range on Protein: 30-192
Range on HMM: 2-141/144.0
NWYDRIDEHVILGALPFRSQaNDLIEKENMKAVVSMNEDYELTAFSNNtekwrklGIEFLQLATTDIFESPNQEKLFRGVEFINKFlplkqrigglsssy
.....|.... || ||. ..  .|. | . ..|....|.|| . . ..       ||..|.| . |    .  | | . .|||...              
snpseilpglylgslptald.lellkklgittvinlteeyepeflere.......giqylhlpwpDhgvpdllellleflefieea..............

QPENvGSVYVHCKAGRTRSATLVGCYLMMKNGWTPDQAVDHMRKCRPHILLHTKQWDALRLFY
..|. | |.|||.||. |..||| .|||.|.|.....|....|..||..  .  |.  |....
leeg.gpvlVHCsaGvgRtgtlvaaylmkklglsleealalvrsrrpgavpnpgqlrfLleye

0048076 (Phosphotyrosine protein) phosphatases II 30-193 6.7e-29 95.8 In-house 2-140 (145) alignment
Range on Protein: 30-193
Range on HMM: 2-140/145.0
NWYDRIDEHVILGALPFRSQaNDLIEKENMKAVVSMnedyeltafSNNTEKWRKLGIEFLQLATTDIFESPNQEKLFRGVEFINKFLPLkqrigglsssy
.|...|.... || ||  ..  .|... . ..|...         ....| . .|||..|.| . |  . .  | | . .|||...|.            
ywpseilpglylgslptald.lellkdlgittvlnl.........tselellerlgiqylylpwpDhgvpdllellleflefieealke...........

qpeNvGSVYVHCKAGRTRSATLVGCYLMMKNGWTPDQAVDHMRKCRPHILLHTKQWDALRLFYT
   . | |.|||.||. |..|||..|||...|.....|....|..||..  .  |.  |..|..
...g.gpvlVHCsaGvgRtgtlvaaylmlllgvsleealelvrsqrpgavpnpgqlrflyefel

0038934 (Phosphotyrosine protein) phosphatases II 31-194 1.1e-32 108.6 In-house 12-175 (194) alignment
Range on Protein: 31-194
Range on HMM: 12-175/194.0
WYDRIDEHVILGALPFRSQANDLIEKENMKAVVSMN-------------EDYELTAFSNNTEKWRKLGIEFLQLATTDIFESPNQEKLFRGVEFINKFLP
. |.| ...|  ..|  .  .. || ... .. .                |.  | .  ..|.. |.|||.|.| . | ...|..| |.| ......|| 
vgdiitgrfiafkvPlsgsldkyieelyrfspedlvrylkllnvklglvidltnteryYdpeefekagieylklpfpddgtvPsleillrfldlvdefln

LKQRigglsssyqpenvGSVYVHCKAGRTRSATLVGCYLMMKNGWTPDQAVDHMRKCRPHILLHTKQWDALRLFYTN
 ..              | |.||||||. |..|||..||....|.....|....| .||... . ....||. .| .
edpg.............gvvaVHCkaGlgRtGtlvaaYLiyrlgmsaeeAialfrekRpgaipnqdyleallkryke

0051082 (Phosphotyrosine protein) phosphatases II 31-185 1.3e-25 85.2 In-house 7-142 (151) alignment
Range on Protein: 31-185
Range on HMM: 7-142/151.0
WYDRIDEHVILGALPfRSQANDLIEKENMKAVVSMNEDYELTafsNNTEKWRKLGIEFLQLATTDIFESPNQEKLFRGVEFINKFLPlkqrigglsssyq
.. .......... |  ..  .|..... |..|......|     ...| ...||||.|..  .|  . . .. .   .||....|              
nfsyvtgglyrsggp.ladflellkelgiktivnlrseeerg...ycpeylpelgievlhipildwpdpglplsfdavleflellld.............

pENVGSVYVHCKAGRTRSATLVGCYLMMkNGWTPDQAVDHMRKCRPHILLHTKQW
  . | |.|||.||. |..|||..|||.  |.....|....|..||..  .  |.
.kkngpvlvHCsaGkgRTGtlvalylml.lgvsleealeeyrlkrpgvvqpnqqf

0043336 (Phosphotyrosine protein) phosphatases II 31-189 1.8e-19 65.7 In-house 50-270 (278) alignment
Range on Protein: 31-189
Range on HMM: 50-270/278.0
WYD--------------------------------RIDEHVILGALPFRSQANDL---IEKENMKAVVSMNEDYELTA----------------------
.|                                 .. ...|.   |  .  .|    . ... . .|...|. ||                        
rykdilpydhsrvklsllggdldsdYinAsyvdgynvprkfiatqgPlpetvedFwrmvwelgvttivmLtelvelgrvkcaqYwpggsltygdftvtll

--------------FSNNTEKWRKLGIEFLQLATTDIFESPNQEKLFRGVEFINKFLplkqrigglsssyqPENVGSVYVHCKAGRTRSATLVGCYLM--
               .|. ... . .  .  |.  |    .. . |.. .......|              . . | |.|||.||  |..|....||.  
keehlddytvrtlevtnlgdgesrtvthyhylgwpdhgvpeslsllldflkavreal..............edsngpvlVHCsaGvgRTGtfialyllle

---MKNGWTPDQAVDHMRKCRPHILLHTKQWDALR
      |.....||...|..||...    |.  |.
qlekeggvdleeavkelreqRpgavqtpsqyrfly

0037934 (Phosphotyrosine protein) phosphatases II 32-192 2.5e-24 81.6 In-house 39-238 (243) alignment
Range on Protein: 32-192
Range on HMM: 39-238/243.0
YDRIDEHVILGALPFRSQAND-------LIEKENMKAVVSMNEDYELTAF------------------------------------SNNTEKWRKLGIEF
. .. ...|.. .|  .  .|       .. ... ...|...|..||...                                      ..... .|.| .
liyvtprliatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqywpgevtygdftvtllseehlddytvrtlllenldlddltrlvihy

LQLATTDIFESPNQEKLFRGVEFINKFLPLKQrigglsSSYQPE-NvGSVYVHCKAGRTRSATLVGCYLMMKN-GWTPDQAVDHMRKCRPH-ILLHTKQW
..|.  |    .. | | . ......|.          | ..   . | |.|||.||. |..||. .|||... |.....||...|..||. .     |.
hylpwpdhgvPdspedlldfldevrefieell......sllaldsg.gpvlVHCsaGvgRtGtliaaylmllllgvdleeavkllreqRpgkavqtpsqy

DALRLFY
  |. ..
rflyeal

subfamily_DSP12_pd Subfamily DSP12 33-195 6.5e-15 49.9 In-house 3-143 (155) alignment
Range on Protein: 33-195
Range on HMM: 3-143/155.0
DRIDEHVILGALPFRSQAnDLIEKENMKAVVSMNEDyELTAFSNNTEKWRKLGIEFLQLATTDIFESpnqekLFRGVEFINKFLplKQrigglsssyqpe
.||.. . || |.   .  .| .. ....|.|. .  ||  ..... | ... |. |   ..||..      | . |.||.. |  ..            
srilpglylggleavqee.ellkelkithvlsvike.elpehklkkgkvstkfiqilDepeediLsh.....ldeavdFieeal..ee............

nVGSVYVHCKAGRTRSATLVGCYLMMKNGWTPDQAVDHMRKCRPHILLHTKQWDALRLFYTNN
  |.|.|||.||  ||.|.|  ||| |...  ..|.. ... .|.|   .   . |.||.   
.egavlvHCqagvSRSvtiviAYlmkkeklslekAlklvkekkpeiepNegFleQLklfekmg

0036282 (Phosphotyrosine protein) phosphatases II 34-191 1.5e-26 88.5 In-house 14-165 (174) alignment
Range on Protein: 34-191
Range on HMM: 14-165/174.0
RIDEHVILGALPFRsqANDLIEKENMKAVVSMNEDYELT------AFSNNTEKWRKLGIEFLQLATTDIFESPNQEkLFRGVEFINKFLplkqrigglss
.| ...|.|. |..    ... ... ..||...| .||        .. . | ...|||..|.| . |  . . .. |.. |.|....|           
yitprliagqgpla..fwemlkelgittvvmlleekelglykcinywpelredlerlgiqylylpwpDhgvpdlsi.llefvkfveeal...........

syQPENVGSVYVHCKAGRTRSATLVGCYLMMKNGW-TPDQAVDHMRKCR---PHILLHTKQWDALRLF
  .  . | |.|||.||. |..|||..|||..... ....|.|..|..|   |..  .  |.  |. |
..sedpggpvlVHCsaGvgRtGtlvaaylmlrglleslvdaldlvrelRlqrpgmvqtpsQyrflyyf

PTPc_motif_SM00404 34-192 8.7e-21 69.3 In-house 4-138 (140) alignment
Range on Protein: 34-192
Range on HMM: 4-138/140.0
RIDEHVILGALPFRSqANDLIEKENMKAVVSMNEDYELTafsnntekWRKLGIEFLQLATTDIFESPNQEKLFRGVEFINKFlplkqrigglsssyqPEN
|| .|..|| ..  .   .|..| ....|... |  .||          . |...||.   |  ... ...| . ..||...                ..
rilphlylgskskaq.npallkklgithvinvteevslt........kensgfqilqiplddnekdklskyldkvldfiena...............ekk

VGSVYVHCKAGRTRSATLVGCYLMMKNGWTPDQAVDHMRKCRPHILLHTKQWDALRLFY
 |.|.|||.|| .|||||. .|||...... ..|.. ... ||.|   .. .  |  ..
ggkvlVHCqaGvSRSatliiaYlmryrqlslaeayefvkerRpiispnlnfvrqLieye

0040439 (Phosphotyrosine protein) phosphatases II 34-191 1.9e-19 65.7 In-house 51-241 (249) alignment
Range on Protein: 34-191
Range on HMM: 51-241/249.0
RIDEHVILGALPFRSQAND---LIEKENMKAVVSMNEDYELTAFS---------------------------------------NNTEKWRKLGIEFLQL
.|  ..|.   |  .  .|   .. ... ...|..... ||                                            . |. . |.| .. .
yikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqywplggsleygdftvtllsvevkddytvrtleltnlydgesrtvlhiqytdw

ATTDIFesPNQEKLFRGVEFINKFLPLKqrigglsssyqpENVGSVYVHCKAGRTRSATLVGCYLM-----MKNGWTPDQAVDHMRKCRPHILLHTKQWD
  ...   |. | |.. .| ..|.|               .. | |.|||.||  |..|....|||      ..|.....||...|..||..     |. 
pdhgvp..psfedlldfieavrkaleel............pkggpvlVHCsaGvgRtGtfiaaylmleqlekelgvdleeavkllrsqRpgavqnpeqyr

ALRLF
 |  .
flyea

0040438 (Phosphotyrosine protein) phosphatases II 35-191 4.7e-20 67.5 In-house 84-271 (317) alignment
Range on Protein: 35-191
Range on HMM: 84-271/317.0
IDEHVILGALPFRSQAND---LIEKENMKAVVSMNEDYELTAFS------------------NNTEKWRKLGIEFLQLATTDI-----------------
.  . |.   |  .  .|   .. ... . .|...|  ||                      ....   . ||. ..|  .|                  
lkrkfIatqgPlpntvedFwrmvweqgvtvivmLteleelgrekcaqYwplgetltygdftvtllseeelagitlrtlevedlgdsesrtvthfhytgWp

-FESP-NQEKLFRGVEFINKFLplkqrigglsssyQpENVGSVYVHCKAGRTRSATLVGCYLM-----MKNGWTPDQAVDHMRKCRPHILLHTKQWDALR
 .  | . . |.. .|.....|             . .. | | |||.||  |..|....|||      ..|.....||...|..||..     |.  | 
dhgvppspdllldfleavreal.............e.dpggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrfly

LF
 .
da

0045450 (Phosphotyrosine protein) phosphatases II 36-191 1.4e-18 63.1 In-house 106-299 (307) alignment
Range on Protein: 36-191
Range on HMM: 106-299/307.0
DEHVILGALPFRSQAND---LIEKENMKAVVSMNEDYELTAF------S-------------NNTEKWRKLGIEFLQLATT-------------------
. . |.   |  .  .|   .. ... ...|...|. ||.        .             .....  . |.  ..|  |                   
krkfIatqgPlpetvedFwrmlweqgvtvivmltelvelgrekcaqywPdegeeltygnftvtllseehldgytvrtlevtdldgtgesrtvthfhytgw

-DIFESPNQEKLFRGVEFINKFLPLkqrigglsssyQPENvGSVYVHCKAGRTRSATLVGCYLMMKNG--------WTPDQAVDHMRKCRPHILLHTKQW
 |   .|. | |.. .| ..|.|              |.. | |.|||.||  |..|....|||....        .....||...|..||..     |.
pdhgvppsfeelldfieevrkalee...........lpkg.gpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqy

DALRLF
  |. .
rflyea

subfamily_Choan-DSP_MKP-1_pd Subfamily Choan-DSP_MKP-1 36-178 5.4e-06 20.0 In-house 12-130 (148) alignment
Range on Protein: 36-178
Range on HMM: 12-130/148.0
DEHVILGALPFRSQANDLiEKENMKAVVSMNEDYElTAFSNNtekwrklGIEFLQLATTDiFESPNQEKLFrgvEFINKFLPLKQRIGglsssyqpenvG
| .. ||. .. .... | .. .. ..|..... .  |. .        |||.|..|  |  .  .  ..|   | | .|.  ..  |           .
dafLFlGskksaadleal.kalgvtrivnatkerd.naldqr.......gieYlhvaldD.kpkedlsaiF...ediiafvrkakdeG...........r

SVYVHCKAGRTRSATLVGCYLMMKNGWTPDQAVDHMRKCRPHI
 | ||.. |. ||. |.  .|.  .  .  .|.. ..  |...
rvLvhlqmGvsrssalallwlidfkrvslkealalvkskrryv

0043147 (Phosphotyrosine protein) phosphatases II 39-191 4.1e-22 74.1 In-house 22-156 (172) alignment
Range on Protein: 39-191
Range on HMM: 22-156/172.0
VILGALPFRSQAN---DLIEKENMKAVVSMNEDyeltafSNNTEKWRKLGIEFLQLATTDIFESpNQEKLFRGVEFINKFLPLKQrigglsssyqpenVG
.| .  |.|.  .   ... ... ...|...|        ...|.  .|||..| |   |     . | | . .|||...| |..              |
fiatqgplrntladfwrmlkelgithivnltel......lydpellerlgiqylylpwpDhgvp.llellleflefidellalsp.............gg

SVYVHCKAGRTRSATLVGCYLMMkNGWTPDQAVDHMRKCRPHILLHTKQWDALRLF
 |.|||.||  |..||| .|||.  |.....||...|..||..  .  |.  |. |
pvlVHCsaGvgRtgtlvaaylml.lglsleeavalvrekRpgavqnpsqyrflyyf

0036941 (Phosphotyrosine protein) phosphatases II 41-191 3.8e-18 61.3 In-house 82-272 (297) alignment
Range on Protein: 41-191
Range on HMM: 82-272/297.0
LGALPFRSQAND---LIEKENMKAVVSMNEDYELTA------FSNNTEKWRKLGIEFLQLATTDI----------------------------------F
.   |  .  .|   .. ..| . .|...|..||        ........ . |  ...| ....                                  .
atqgPlpntvedFWrmvweqnvtvIvmltelvelgrekcaqywpleegesltygdftvtllsvevvllddytlrtlevtdtgngesrtvthfhytgwpdh

ESPN-QEKLFRGVEFINKFLPLKqrigglsssyqPENvGSVYVHCKAGRTRSATLVGCYLM--------MKNGWTPDQAVDHMRKCRPHILLHTKQWDAL
  |.  . |.. .|...|.|.|            |.. | |.|||.||  ||.|.....||        . .|... .|| ..|..||..     |.  |
gvpespaslldfielvrkvlkll...........psg.gpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrfl

RLF
. .
yea

0049260 (Phosphotyrosine protein) phosphatases II 53-191 3.5e-22 74.2 In-house 28-145 (152) alignment
Range on Protein: 53-191
Range on HMM: 28-145/152.0
LIEKENMKAVVSMNEDYEltafsnNTEKWRKLGIEFLQLATTDIFESPNQEKLFRGVEFINKFLPLKQRigglsssyqpenvgSVYVHCKAGRTRSATLV
.. . . ...|...|..|      ... . . .|..|.| . |    .. . |   ..||.|..  |.                |.|||.||  |..|||
mlkelgittivmltelle......lgklkceqyiqylhlpwpDhgvpdlsqlllflllfieklaldkgg..............pvlVHCsaGvgRtgtlv

GCYLMMkNGWTPDQAVDHMRKCRPHILLHTKQWDALRLF
 .|||. .|.....||...|..||..  .  |.  |  |
aaylml.lgvsleeavalvrekRpgavpnpgqlrflyef

0047943 (Phosphotyrosine protein) phosphatases II 53-186 2.6e-18 61.9 In-house 96-262 (273) alignment
Range on Protein: 53-186
Range on HMM: 96-262/273.0
LIEKENMKAVVSMNEDYELTA------FSNNTE----------------------KWRKLGIEF-----------LQLATTDIFESP-NQEKLFRGVEFI
.. ..| . .|...|..||        .... .                      ..|.| ...           ..  .   .  | . | |.. .|..
mvweqnvrviVmLtelvelgrekcaqYwpleggelsltygkftvtllseetkddytvrtleltnlgtgesrtvthfhytgwpdhgvppslesllefielv

NKFLPL--KQrigglsssyqpenvGSVYVHCKAGRTRSATLVGCYLM-----MKNGWTPDQAVDHMRKCRPHILLHTKQWD
.|.|    ..              | |.|||.||  |..|.. ..|.     ...|.....|| ..|..||..     |. 
rkalealpsn..............gpvvVHCsaGvgRtgtfialdllldqlekeggvdvleavkllrsqRpgmvqtpeqyr

0051429 (Phosphotyrosine protein) phosphatases II 53-193 6.3e-16 54.3 In-house 40-222 (272) alignment
Range on Protein: 53-193
Range on HMM: 40-222/272.0
LIEKENMKAVVSMNEDYELTAFSNNTEKwrkLGIEFLQLATTDIFESPNQ--------------------------------------------------
 ..... |..|.. ...|. ..    .     ||..|.| . |  . .                                                    
rlkelgiktivdLrseeErgrlkcdryw...pgirylhlpilddsaptilygalrvtllseellldyilrellltlllsagearevmhlhytdwpdhgvp

-EKLFRGVEFINKflplkqrigglsssyqpenVGSVYVHCKAGRTRSATLVGCYLMMkNGWT--------------PDQAVDHMRKCRPHILLHTKQWDA
 | | . .|....                    | |.|||.||. |..|.| ..|..  |..              ...||...|..||..  .  |.  
qeallellellld...................ggpvlvHCsaGkdRTGtvvalllll.lgvsletivddYlltnlyleeaveelraqrpgavqteeqylf

LRLFYT
|. .. 
lyeall

0050432 (Phosphotyrosine protein) phosphatases II 53-184 1.6e-15 52.7 In-house 127-287 (308) alignment
Range on Protein: 53-184
Range on HMM: 127-287/308.0
LIEKENMKAVVSMNEDYELTA------FSNNTE---------------------------------KWRKLGIEFLQLATTDIFESPN-QEKLFRGVEFI
.. ..| . .| ... .|         . ....                                 .   . .  ..  .   .  |.  | |.. .|..
mvweqnvrvIvmLtklvengrekcaqYwplelgggsleygkftvtllseevlddytvrtleltnlgdgesrtvthfhytnWpdhgvPpspeilldflelv

NKFLplkqriGGlsssyqpenvGSVYVHCKAGRTRSATLVGCYLM-----MKNGWTPDQAVDHMRKCRPHILLHTKQ
.|.|      .|          | ..|||.||  |..|.. ..|.     ...|... .|| ..|..||.      |
rksl......pg..........gpivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkklReqRpgmvqtpeq

0051299 (Phosphotyrosine protein) phosphatases II 53-184 1.8e-14 49.3 In-house 111-274 (288) alignment
Range on Protein: 53-184
Range on HMM: 111-274/288.0
LIEKENMKAVVSMNEDYELTA-------------------------FSNN----------------TEKWRKLGIEFLQLATTDIFESPNQEKLFRGVEF
.. ..| . .|.... .||                            ...                 ..  .  . |  ..  |    .. | |.. ...
mvweqnvrvIvmltklvelgrekcaqYwplggsltygditvtllseevlddytvrtlevtnldlldgdgesrtvthfhytnwpdhgvpdspellldflrl

INKFLPlkqrigglsssyqpENVGSVYVHCKAGRTRSATLVGCYLM-----MKNGWTPDQAVDHMRKCRPHILLHTKQ
..|.|.               . | |.|||.||  |..|.. ..|.      ..|... .|| ..|..||..     |
vrkala..............sgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlreqRpgmvqtpeq

0046845 (Phosphotyrosine protein) phosphatases II 54-187 1.5e-14 49.5 In-house 97-265 (284) alignment
Range on Protein: 54-187
Range on HMM: 97-265/284.0
IEKENMKAVVSMNEDYELT------------------------------------AFSNNTEKWRKLGIEFLQ---LATTDIFESPNQEKLFRGVEFINK
. ..| . .|...|  |                                       ..   ... .  ..  .   ..  |    |. | |.. ......
vweqnvrvIVmltelvengrekcaqYwplegevltygdftvtllseevkddytvrtleltnlgytgesrtvthfhytswpdhgvppspedlleflrlvre

FLPLkqrigglsssyqPENVGSVYVHCKAGRTRSATLVGCYLMMKN--------GWTPDQAVDHMRKCRPHILLHTKQWDA
.|.              .. | . |||.||  |..|.. ..|...         |... .|| ..|..||.      |   
llen............lpgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvqtleqyrf

Y_phosphatase Protein-tyrosine phosphatase 58-185 1.8e-07 26.2 Pfam-A 105-226 (235) alignment
Range on Protein: 58-185
Range on HMM: 105-226/235.0
NMKAVVSMNEDYELTAFSNNTEKWRK--LGIEFLQLATTDIFESPnqEKLFRGVEFINKFLPLKqrigglsssyqPENVGSVYVHCKAGRTRSATLVGCY
... . . ...| |. .. . .|...    .. |.. .    . |  |.    ...|.|.   |            .. |.| |||.||  |..|.|   
lkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvp..espkslldlirkveksk...........eaksgpvvVhCsaGvgRtgtfvald

LMMKNGWT-----PDQAVDHMRKCRPHILLHTKQW
.....  .       |.| ..||.||..    .| 
illeqleaeeevdvlqivkelRkqRpgmvqsleqY

Y_phosphatase Protein-tyrosine phosphatase 58-185 1.8e-07 26.2 In-house 105-226 (235) alignment
Range on Protein: 58-185
Range on HMM: 105-226/235.0
NMKAVVSMNEDYELTAFSNNTEKWRK--LGIEFLQLATTDIFESPnqEKLFRGVEFINKFLPLKqrigglsssyqPENVGSVYVHCKAGRTRSATLVGCY
... . . ...| |. .. . .|...    .. |.. .    . |  |.    ...|.|.   |            .. |.| |||.||  |..|.|   
lkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvp..espkslldlirkveksk...........eaksgpvvVhCsaGvgRtgtfvald

LMMKNGWT-----PDQAVDHMRKCRPHILLHTKQW
.....  .       |.| ..||.||..    .| 
illeqleaeeevdvlqivkelRkqRpgmvqsleqY

0048567 (Phosphotyrosine protein) phosphatases II 60-192 4.8e-26 85.9 In-house 2-135 (157) alignment
Range on Protein: 60-192
Range on HMM: 2-135/157.0
KAVVSMNEDYELTAFSNNTEKWRKLGIEFLQLATTD--IFESPNQE----KLFRGVEFINKFLPLKQRIGGLSssyqpenvGSVYVHCKAGR---TRSAT
|......|... . . ..   ..|   ..|.. ..|  ..|.. ..    .| . ..||.|. .. . .   .        . ..||||||.   .|.||
kengdlieiipdrlyfallprlpkslynalyFsiddglvyedfffdfGPlnlailyrFilklnkflkilelag........kaiavhckaglkkrgrtat

LVGCYLMMKNGWTPDQAVDHMRKCRPHILLHTKQWDALRLFY
|.||||....|.||..|....| .||..... ... .|.|..
LigcYlilhlgftpeeaiaplrivrpgsvpfrdasyllslyn

0049772 (Phosphotyrosine protein) phosphatases II 60-190 5.2e-24 81.0 In-house 167-268 (314) alignment
Range on Protein: 60-190
Range on HMM: 167-268/314.0
KavvsmnedyeltAFSNNTEKWRKLGIEFLQLATTDiFESPNQEKLFRGVEFINKFlPlkqrigglsssyqpeNVGSVYVHCKAGRTRSAT-LVGCYLMM
|               .. |.. .|||..|.. ..| .. |  | . . .|||... .               . | |.||||||. |..| .| .|||.
k............eelydpelferlgikylripvpD.gsaplledfdeflefieea.d...............kggpvlvHCkaGkgRtgtfvvaaylmk

KNGWTPDQAVDHMRKCRPhILLHTKQWDALRL
..|.....|....|..|| |  .  ..  |..
llgvsleealedvrlkRp.inpnpgfieqleq

DSPc Dual specificity phosphatase, catalytic domain 63-192 1.4e-17 58.8 Pfam-A 11-131 (133) alignment
Range on Protein: 63-192
Range on HMM: 11-131/133.0
VSMNEDYELTAFSNNTEK------WRKLGIEFLQLATTDIFESPNQEKLFRGVEFINKFlplkqrigglsssyqPENVGSVYVHCKAGRTRSATLVGCYL
 ...|....|.  | |..        |  ||.|..   |  |.  ...| . ||||.|.                .. ..|.|||.|| .|||||. .||
lalleklgitlvinvtkevpnnnaikkseieylripvedetetkiskeleeavefieka...............eqkgkkvlVHCqaGisRSatliiaYl

MMKNGWTPDQAVDHMRKCRPHILLHTKQWDALRLFY
|...... ..|...... |..|   ....  |. ..
mktknlslneAyefvkerrskispnagflrqLleye

DSPc Dual specificity phosphatase, catalytic domain 63-192 1.4e-17 58.8 In-house 11-131 (133) alignment
Range on Protein: 63-192
Range on HMM: 11-131/133.0
VSMNEDYELTAFSNNTEK------WRKLGIEFLQLATTDIFESPNQEKLFRGVEFINKFlplkqrigglsssyqPENVGSVYVHCKAGRTRSATLVGCYL
 ...|....|.  | |..        |  ||.|..   |  |.  ...| . ||||.|.                .. ..|.|||.|| .|||||. .||
lalleklgitlvinvtkevpnnnaikkseieylripvedetetkiskeleeavefieka...............eqkgkkvlVHCqaGisRSatliiaYl

MMKNGWTPDQAVDHMRKCRPHILLHTKQWDALRLFY
|...... ..|...... |..|   ....  |. ..
mktknlslneAyefvkerrskispnagflrqLleye

subfamily_DSP3_pd Subfamily DSP3 66-175 2.8e-11 37.3 In-house 44-138 (162) alignment
Range on Protein: 66-175
Range on HMM: 44-138/162.0
NEDyELTAFSNNTEKWRKLGIEFLQLATTDIFESPNQEKLFRGVEFINKFLPLkqrigglsssyqpeNVGSVYVHCKAGRTRSATLVGCYLMMKNGWTPD
 |  ...    ..| ...|.|..| |  .| .|.  ..   . ..||.. |                . | |.|||..|  ||||||  |||...  |  
aeg.rfskvdtgaefykdleikylGlevdDvpefdlskyFetaakfidealsq..............kegkvlvhcvvGvsRsatlvlayLmirrkmtlv

QAVDHMRKCR
.|. ..|| |
eairtvrkkR

DSPc_SM00195 66-185 5.7e-07 24.5 In-house 151-251 (263) alignment
Range on Protein: 66-185
Range on HMM: 151-251/263.0
NE--DYELTAFSNNTEKWRKLGIEFLQLATTDIFESPNQEKLFRgvefinkflplkqrigglsssyqpenVGSVYVHCKAGRTRSATLVGCYLMMKNG--
.|  . . ..   . ..| . |.   .  ....... ...|                              | . |||.||  |..|.|   .....   
kegkeetrkvtqyqyknWpdhgvpdstksvlellravkksksts..........................sgpivVhCsaGvgRtgtfvtidiilsklee

---WTPDQAVDHMRKCRPHILLHTKQW
      .. | ..|| ||..    .|.
ekkvdifeivkelRkqRpgmvqtleqY

PTPc_SM00194 66-185 5.7e-07 24.5 In-house 151-251 (263) alignment
Range on Protein: 66-185
Range on HMM: 151-251/263.0
NE--DYELTAFSNNTEKWRKLGIEFLQLATTDIFESPNQEKLFRgvefinkflplkqrigglsssyqpenVGSVYVHCKAGRTRSATLVGCYLMMKNG--
.|  . . ..   . ..| . |.   .  ....... ...|                              | . |||.||  |..|.|   .....   
kegkeetrkvtqyqyknWpdhgvpdstksvlellravkksksts..........................sgpivVhCsaGvgRtgtfvtidiilsklee

---WTPDQAVDHMRKCRPHILLHTKQW
      .. | ..|| ||..    .|.
ekkvdifeivkelRkqRpgmvqtleqY

P53_C Transcription factor P53 - C terminal domain 67-122 2.4e-06 13.8 Pfam-A 15-67 (71) alignment
Range on Protein: 67-122
Range on HMM: 15-67/71.0
EDYELTAFSNNTEkWRKLGIE-FLQLATTDIFESPNQEKLFRgveFINKFLPLKQRI
 || |.    | | |    || ... |.....  |||| | |     ||.| ||.| 
Gdyrlaitcpnke.wllqsieGmikeaaaevlrnpnqenlrr...hankllslkkra

subfamily_RNGTT_pd Subfamily RNGTT 77-188 6.2e-09 29.8 In-house 69-167 (189) alignment
Range on Protein: 77-188
Range on HMM: 69-167/189.0
NTEKWRKLGIEFLQLATTDIFESPNQEKLFRGVEFINKFLPlkqrigglsssYQPENVgsVYVHCKAGRTRSATLVGCYLMMKNGWTPDQAVDHMRKCRP
..|.  | ||.. .|...   |.|..|.  .  . ...|              .||.|  . |||. |  |.  |. .||. |. |  ..||.  .|.||
dkeelekegikyvklqcagkgeaPeaeqvkefiklveeffk...........knpeev..igvhCthGfnRtGFlivsyLvekedwsveaavalFakaRp

HILLHTKQWDAL
  . . .  . |
pGiykedylkel

subfamily_DSP11_pd Subfamily DSP11 77-183 4.8e-07 23.8 In-house 71-165 (178) alignment
Range on Protein: 77-183
Range on HMM: 71-165/178.0
NTEKWRKLGIEFLQLATTDIfESPNQEKLFRGVEFINKFLplkqrigglssSYQPENVGSVYVHCKAGRTRSATLVGCYLMMKNGWTPDQAVDHMRKCRP
..... . |...|.| ..   | |..| . .  |....||            .. .|   . |||  |  |.  |.  ||. ..|. |..|.. . ..| 
kkkeltdegvkylklncpGh.evpkeelvkkfkeavkefl...........eknkdndkligvhCthGvnrtGyliCrylidvegyepedaieafeearG

HILLHTK
| | . .
hsleren

subfamily_Dicty-DSP19-like_pd Subfamily Dicty-DSP19-like 78-179 2e-07 24.5 In-house 48-136 (154) alignment
Range on Protein: 78-179
Range on HMM: 48-136/154.0
TEKWRKLGIEFLQLattDIFESPNQ---EKLFRGVEFInkflplKQRIGGLSSsyqpenvGSVYVHCKAGRTRSATLVGCYLMMKNGWTPDQAVDHMRKC
..    . ||.|.|   ..|. .|.   ||| .  |||      .. |||.         . | ||...| .|||.|.  ||| |   .  .|.  ....
sdindgfiieylnl...elfddvnfdiiekldkafefi......ddaiggven.......nkvlvhsdkGvsrsaallisylmdklkislslalellkds

RPHIL
|. | 
ryiik

PTPc_DSPc_SM00012 124-181 3.6e-08 28.9 In-house 38-92 (105) alignment
Range on Protein: 124-181
Range on HMM: 38-92/105.0
GlsssyqpenVGSVYVHCKAGRTRSATLVGCYLMMKNGWTP------DQAVDHMRKCRPHILLH
           ..| |||.||  |..|.|  ...... ..        | | ..|| ||.    
s.........skpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgmvqt

subfamily_PRL_pd Subfamily PRL 125-186 1.7e-06 22.2 In-house 81-140 (151) alignment
Range on Protein: 125-186
Range on HMM: 81-140/151.0
LSSSYQPENVGSVYVHCKAGRTRSATLVGCYLmMKNGWTPDQAVDHMRKCRPHIlLHTKQWD
| .... |.  .| ||| ||  |.  ||   | . .| ....||. .|. |    . .|| .
lkekfkeepkstvavhcvaGlGraPvlvalal.ieaGmkyedavefirekrrga.inskqlk

subfamily_MKPLT_pd Subfamily MKPLT 132-175 1.9e-07 24.8 In-house 97-140 (164) alignment
Range on Protein: 132-175
Range on HMM: 97-140/164.0
ENVGSVYVHCKAGRTRSATLVGCYLMMKNGWTPDQAVDHMRKCR
.. | |.|||  |..||..    .|.  .||| ..| ..... |
dsGGrvlvhcvqGksrsssvtvafLikskgwtlkeayeylkerr

subfamily_MKPLV_pd Subfamily MKPLV 132-175 1.9e-07 24.8 In-house 97-140 (164) alignment
Range on Protein: 132-175
Range on HMM: 97-140/164.0
ENVGSVYVHCKAGRTRSATLVGCYLMMKNGWTPDQAVDHMRKCR
.. | |.|||  |..||..    .|.  .||| ..| ..... |
dsGGrvlvhcvqGksrsssvtvafLikskgwtlkeayeylkerr

subfamily_Laforin_pd Subfamily Laforin 132-179 3.3e-06 20.1 In-house 108-155 (183) alignment
Range on Protein: 132-179
Range on HMM: 108-155/183.0
ENVGSVYVHCKAGRTRSATLVGCYLMMKNGWTPDQAVDHMRKCRPHIL
|.   |||||.||  ||...|  .|.   ||.  .   ..   || . 
ekghivyvhcnagvgrstaivcgflqyvlgwslakvqyfllakrpvvy

subfamily_DSP19_pd Subfamily DSP19 133-179 5e-12 40.4 In-house 89-134 (152) alignment
Range on Protein: 133-179
Range on HMM: 89-134/152.0
NvGSVYVHCKAGRTRSATLVGCYLMMKNGWTPDQAVDHMRKCRPHIL
. | |.|||.||. |||..|  ||| |.  .  .|.. .|. || | 
d.gavlvHCnAGvSRsasvviaylmkkeelsleealelvrearpcik

subfamily_DSP1_pd Subfamily DSP1 133-178 4.4e-10 33.9 In-house 94-139 (163) alignment
Range on Protein: 133-178
Range on HMM: 94-139/163.0
NVGSVYVHCKAGRTRSATLVGCYLMMKNGWTPDQAVDHMRKCRPHI
. | |..||.||  ||.||.  |||... .. ..| | ... |. |
knGkvlihCqaGisRsstlclaylmktkrvsleeafdfvkqrRsii

subfamily_DSP14_pd Subfamily DSP14 133-189 5.6e-10 33.4 In-house 82-138 (157) alignment
Range on Protein: 133-189
Range on HMM: 82-138/157.0
NVGSVYVHCKAGRTRSATLVGCYLMMKNGWTPDQAVDHMRKCRPHILLHTKQWDALR
. | . |||.||. |||.|.  |||  .  .  .|  .....|| |   .  |  |.
kggktlvhCvaGvSRSAslclaylmkyeklsLreayklvksaRpiirPNvGFwkqli

subfamily_CDC14_pd Subfamily CDC14 134-183 1.1e-11 39.2 In-house 263-312 (328) alignment
Range on Protein: 134-183
Range on HMM: 263-312/328.0
VGSVYVHCKAGRTRSATLVGCYLMMKNGWTPDQAVDHMRKCRPHILLHTK
 |.. ||||||  |  ||..|||| . . |  .|. ..| |||  ..  .
eGaiavhCkaGLGrtGtLiacylmkhyrftaaeaiawlricrPGsvigpq

subfamily_LRR-DSP_pd Subfamily LRR-DSP 134-186 5.3e-11 36.1 In-house 197-249 (263) alignment
Range on Protein: 134-186
Range on HMM: 197-249/263.0
VGSVYVHCKAGRTRSATLVGCYLMMKNGWTPDQAVDHMRKCRPHILLHTKQWD
 | | |||.|| .||.||| .|||.|.  .  .|.| . | ||.|   .   |
kGGvlvhcraGvsrsstlvisylmkkqrlkfkealdlvikkrpriqPnpGfkd

subfamily_DSP15_pd Subfamily DSP15 134-176 1.6e-08 28.8 In-house 78-120 (151) alignment
Range on Protein: 134-176
Range on HMM: 78-120/151.0
VGSVYVHCKAGRTRSATLVGCYLMMKNGWTPDQAVDHMRKCRP
 ..|.||| ||  ||.|||  |||        .|.. ....| 
eenvlvhClaGvsRsvtlvvaYlmtvtelnwrdalevikaaRs

subfamily_DSP8_pd Subfamily DSP8 134-178 8.8e-08 25.9 In-house 93-137 (159) alignment
Range on Protein: 134-178
Range on HMM: 93-137/159.0
VGSVYVHCKAGRTRSATLVGCYLMMKNGWTPDQAVDHMRKCRPHI
 |.| ||. ||. ||||.. .|.| .   . |.|  .... || |
ngrvlvhvlaGisrsatvaiayimktlemsldeayrfvkekrpti

subfamily_PTPDC1_pd Subfamily PTPDC1 135-191 3.8e-11 37.8 In-house 115-171 (182) alignment
Range on Protein: 135-191
Range on HMM: 115-171/182.0
GSVYVHCKAGRTRSATLVGCYLMMKNGWTPDQAVDHMRKCRPHILLHTKQWDALRLF
| | ||| ||. |   |. |||. ..  |...|.. .|. ||. .   .| . .. |
gkvavhChaGlGrtGvliacylvyakrltaekaiklvrskrpksiqtreqvelvkef

subfamily_DSP10_pd Subfamily DSP10 135-178 6.6e-09 29.8 In-house 93-136 (159) alignment
Range on Protein: 135-178
Range on HMM: 93-136/159.0
GSVYVHCKAGRTRSATLVGCYLMMKNGWTPDQAVDHMRKCRPHI
 .| |||.||  ||||.|  ||| . . .  .| ......|| |
srvLvhCqaGisrsatvviaYlmkhlnlslndaykfvkekrpii

subfamily_Slingshot_pd Subfamily Slingshot 135-178 1.1e-08 28.7 In-house 97-140 (169) alignment
Range on Protein: 135-178
Range on HMM: 97-140/169.0
GSVYVHCKAGRTRSATLVGCYLMMKNGWTPDQAVDHMRKCRPHI
 .| |||| | .|||. |  | | . |.. ..|...... |  |
skvlvhckmGvsrsastviayamkeyglsleealeyvkerrsvi

subfamily_DSP23_pd Subfamily DSP23 135-189 3.4e-08 28.3 In-house 85-139 (148) alignment
Range on Protein: 135-189
Range on HMM: 85-139/148.0
GSVYVHCKAGRTRSATLVGCYLMMKNGWTPDQAVDHMRKCRPHILLHTKQWDALR
 .| |||  || |. |.. |||. ... .  .|.  .|. ||  .   .| ...|
eavsvhcllgrgrtgtmlacylvkerklaaaeaiaevrrlrpgsvetveqeklvr

subfamily_STYXL1_pd Subfamily STYXL1 135-179 4.4e-08 26.5 In-house 93-137 (157) alignment
Range on Protein: 135-179
Range on HMM: 93-137/157.0
GSVYVHCKAGRTRSATLVGCYLMMKNGWTPDQAVDHMRKCRPHIL
  | |  . | .|||... .||| .. .|  .| ....||.. . 
evvlvfsnkGisrsaaviiaylmyskkitlkkaykylkkCkenvk

subfamily_DSP6_pd Subfamily DSP6 135-178 7.1e-08 26.1 In-house 94-137 (158) alignment
Range on Protein: 135-178
Range on HMM: 94-137/158.0
GSVYVHCKAGRTRSATLVGCYLMMKNGWTPDQAVDHMRKCRPHI
 .| ||| || .|| |.. .||| |.  . ..| | ..| ...|
skvlvhClaGisrsvtvtlaylmkklalslndaydlvkkrksni

subfamily_PTEN_pd Subfamily PTEN 136-175 2.8e-06 22.4 In-house 116-156 (184) alignment
Range on Protein: 136-175
Range on HMM: 116-156/184.0
SVYVHCKAGRTRSATLVGCYLMMKNGWTP-DQAVDHMRKCR
 | ||||||. |. .|. .||. .. ..  ..|...  . |
vvvvHCkaGkGRtGvlivayllkslllekaeealelfaeaR

DSPn Dual specificity protein phosphatase, N-terminal half 142-178 1e-07 22.7 Pfam-A 78-114 (141) alignment
Range on Protein: 142-178
Range on HMM: 78-114/141.0
KAGRTRSATLVGCYLMMKNGWTPDQAVDHMRKCRPHI
.  |...|.|.|.|........|..|.. ...  |..
ekkranaalLigaYavivlklspeealkplesvepsl