Gene PTP-ER in Drosophila melanogaster

Synonym: CG9856, Dmel\CG9856, ER2-5, ptp-er, Dmel_CG9856, PTP-ER

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family PTP
Subfamily PTPN5_RR
Protein sequence
ID Type Fasta BLAST phosphatome Note
DmelP044_AA protein Get Run
DmelP044_AA_887-1369 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_Anemone-PTP-2_pd Subfamily Anemone-PTP-2 873-1001 3.9e-12 41.0 In-house 14-124 (298) alignment
Range on Protein: 873-1001
Range on HMM: 14-124/298.0
VSRMAQPIPELKENEQKRIFRDLHKEFWDLPLNHQEKPMVFGSQTKNRYKTILPNENSRVLLESESSEltsllgeikrtssvtasEDLPYINANYIKGPD
....|.  .. |    .  |. |..   ... ...|       . ||||  |.. . |||.||.|...                 |.  |||| .... .
lqklaavkkkkkltgyalefqrlnsvsseieeeekevarkpenkkkNRyadiialdssRvvLekedad.................eesdYiNAsflhayk

YVSkCYVATQGPLPNTIFEFWLMIYQNTQ
  .  ..|||.||..|. .|| |. ..  
grn.afiatqaPltetvedFWrmvteedi

subfamily_PTPRA_pd Subfamily PTPRA 880-1000 3e-10 34.5 In-house 16-125 (330) alignment
Range on Protein: 880-1000
Range on HMM: 16-125/330.0
IPELKENEQKRIFRD---LHKEFWDLPLNHQEKPM----VFGSQTKNRYKTILPNENSRVLLesesseltsllgeikrtSSVTASEDLPYINANYIKGPD
. .|.|. ..|.  |   ...||  ||  . .  .        . |||.  |||.. ||| |                 | .   |.  |||| .|.|  
vekleeeirirsaddnklfreefnalPagpiqatlelaskeenkeknrvvnilPydfsrvil.................svkeGveesdyinasfidGyk

YvSKCYVATQGPLPNTIFEFWLMIYQNT
   . ..|.|||. .|. .|| ||..  
e.kdkfiaaqGPkeetvedfwrmiweqk

subfamily_PTPN1_pd Subfamily PTPN1 887-1003 1.9e-11 38.2 In-house 7-98 (290) alignment
Range on Protein: 887-1003
Range on HMM: 7-98/290.0
EQKRIFRDLHKEFWDLPLNHQEKPMvfgSQTKNRYKTILPNENSRVLLESESSeltsllgeikrtssvtasedlPYINANYIKGPDyVSKCYVATQGPLP
  | |..|..||  |.| .. ..|     ...|||. . | . ||. ||...                       ||||. .. .. . . |. ||||||
lykeiyldirkeasdfptreaklpe...nrnlnryrdvspydhsrikleradn.....................dyinaslvelee.akrsyiltqGPlp

NTIFEFWLMIYQNTQRY
||.  ||.|....  . 
ntvdhfWqmvWeqkska

0040438 (Phosphotyrosine protein) phosphatases II 888-1371 6.1e-52 172.2 In-house 16-279 (317) alignment
Range on Protein: 888-1371
Range on HMM: 16-279/317.0
QKRIFRDLHKEFWDLPLNHQEKPMVFGSQTKNRYKTILPNENSRVLLESesseltsllgeikrtssVTASEDLPYINANYIKGPDYVSKcYVATQGPLPN
....... .... .|.|.. .  .   .. ||||. |||...||| | .                 ..  .|. ||||.|..||..  | ..||||||||
dftalleefedllslkldtysvaelpenkdknrypdilpydhsRVkLsp.................lggdldsdYInAsyvdgpnlkrk.fIatqgPlpn

TIFEFWLMIYQNtqryirrcvdggssssphvdreqilqqYFQKIVMLTNFTEANRQKCAVYFPIelNEIFAVAakcevfqlsaaardyfdryltptfvpd
|.. || |....                             . |||||...| .|.||| |.|   .|   .                            
tvedFwrmvweq...........................gvtvivmLteleelgrekcaqYwpl..getltyg...........................

tvvassdaidyeisgrhigvesvkvtlegdllealpaqgsFFLIKNVGIVRRNGYSVRKLVLLYCirvpqsasYHLQKIYCYHYWYPDWPDHHSPRDINT
                                         | .......  .|. .|.| . .         .. .. ...|..|..||||. | ....
........................................dftvtllseeelagitlrtlevedl........gdsesrtvthfhytgWpdhgvppspdl

LLDTCLHVLNLGkcesefdiyddtrsernahlaaqrleiyqqdifNAVQPLPVIHCSAGIGRTGCFTAILNAVRQLRqslaysltgmltksltsssteey
||| .  | .                                   .  .   ..|||||.||||.| |.. ...||.                       
lldfleavreal.................................edpggpvlVHCsaGvgRtGtfiaaylmleqle.......................

hnptdsdssftcntirhishildhrdaeavktppsfdrlpkmPDIFVDVLGIVCNLRLQRGGMVQNSEQYELIHRAICLYLKRT
                                             .|||  .|. || ||.|.||. |||. ...|.. ||||.
..........................................keggvdveeavkelreqRpgavqtpeqyrflydalleylkrk

0036941 (Phosphotyrosine protein) phosphatases II 888-1056 6.4e-25 83.5 In-house 15-131 (297) alignment
Range on Protein: 888-1056
Range on HMM: 15-131/297.0
QKRIFRDLHKEFWDLPLNHQEKPmvfGSQTKNRYKTILPNENSRVLLESESseltsllgeikrtssvtasedLPYINANYIKGPDYVSKcYVATQGPLPN
 .. |..| . ... .|.....|   . ..||||| |||....|| |..|.                       ||||.|..|.|.  | ..||||||||
llkefeellpllllgslsvallp...enleknRykdilpydhtRVklddeg.....................sdYinAsyvdgydlkrk.fIatqgPlpn

TIFEFWLMIYQNtqryirrcvdggssssphvdreqilqqYFQKIVMLTNFTEANRQKCAVYFPIELNEI
|. .|| |....                             . |||||...| .|.||| |.| | .| 
tvedFWrmvweq...........................nvtvIvmltelvelgrekcaqywpleeges

subfamily_PTPN5_RR_pd Subfamily PTPN5_RR 889-1374 1.1e-131 433.0 In-house 1-274 (274) alignment
Range on Protein: 889-1374
Range on HMM: 1-274/274.0
KRIFRDLHKEFWDLPLNH-QEKPMVFGSQTKNRYKTILPNENSRVLLESESSEltsllgeikrtssvtaSEDLPYINANYIKGPDYVSKCYVATQGPLPN
||.|.||.|||..||||. ||...|||||||||||||||||||||||||||||                .||..|||||||||.|..||.||||||||||
krsfkdlekeflelPlnfdqeeldvfgsqtknryktilPnensrvllesesse................dedssyinanyikGydeeskayvatqGPlpn

TIFEFWLMIYqntqryirrcvdggssssphvdreqilQQYFQKIVMLTNFTEANRQKCAVYFPielneifavaakcevfqlsaaardyfdryltptfvpd
|...||.|||                           |...|.|||||...|||.||||||||                                     
tvadfWrmiy...........................qeevqvivmltklkeaneqkCavyfP.....................................

tvvassDAIDYEISGRHIGVEsvkvtlegdllealpaqgsfflIKNVGIVRRNGYSVRKLVLLYCIRvPQSasyhlqkiyCYHYWYPDWPDHHSPRDINT
      ||.|||||.|...||                      ||...||.||.||||||||.|..| ..|         ..||||.|||||.||.|.||
......daedyeiserygdve......................ikvekiverndysvrklvlkyler.ers.........vkhywytdWPdhksPddant

LLDTCLHVlnlgkcesefdiyDDTRSERNAHLAAQrleiyqqdifnavqplpVIHCSAGIGRTGCFTAILNAVRQLRQslaysltgmltksltsssteey
|||..|.|             ...|.|.||.||..                 |.||||||||||||.||..||||||.                      
lldlvlev.............eesreeenaklapv.................vvhCsaGiGrtGcfiaisiavrqlre......................

hnptdsdssftcntirhishildhrdaeavktppsfdrlpkmpDIFVDVLGIVCNLRLQRGGMVQNSEQYELIHRAICLYLKRTLAL
                                           .|.||||.|||||||.||||||.||||||||||.||||||.|||
...........................................eivvdvlkivcnlrldrGGmvqtseqyelihralclylkrllal

0043336 (Phosphotyrosine protein) phosphatases II 889-1055 3.9e-24 81.0 In-house 19-136 (278) alignment
Range on Protein: 889-1055
Range on HMM: 19-136/278.0
KRIFRDLHKEFWDLPLNHQEKPMVFGSQTKNRYKTILPNENSRVLLESesseltsllgeikrtssVTASEDLPYINANYIKGPDYVSKcYVATQGPLPNT
|....  ..|... .|....  .   ...||||| |||...||| |..                 ..  .|. ||||.|..|...  | ..|||||||.|
ktllllefeellsfkldtysiallpenkdknrykdilpydhsrvklsl.................lggdldsdYinAsyvdgynvprk.fiatqgPlpet

IFEFWLMIYQNtqryirrcvdggssssphvdreqilqqYFQKIVMLTNFTEANRQKCAVYFPielnE
.  || |....                             . |||||...| .|.||| |.|    .
vedFwrmvwel...........................gvttivmLtelvelgrvkcaqYwp....g

subfamily_PTPRD_pd Subfamily PTPRD 892-1003 3.9e-16 53.8 In-house 29-118 (564) alignment
Range on Protein: 892-1003
Range on HMM: 29-118/564.0
FRDLHKEfWDLPLNHQEKPMvfgSQTKNRYKTILPNENSRVLLesesseltsllgeikrtSSVTASEDLPYINANYIKGPDyVSKCYVATQGPLPNTIFE
.......    . .. .||.    . ||||. |.. ..||| |                 |.| . |.  ||||..|.| .  .| |.||||||..|| .
ykkieeg.qqftweaankpa...NkaKNRyanivaYdhsRVvL.................skvegdegsDYINAsfidgyr.krkayIAtqgPlaetied

FWLMIYQNTQRY
|| |....  . 
FWRmvweqnsst

0050432 (Phosphotyrosine protein) phosphatases II 893-1054 6e-27 90.2 In-house 42-159 (308) alignment
Range on Protein: 893-1054
Range on HMM: 42-159/308.0
RDLHKEFWDL----PLNHQEKPMVFGSQTKNRYKTILPNENSRVLLesesseltsllgeikrtssvtaSEDLPYINANYIKGPD-YVSKCYVATQGPLPN
  |..||..|    ||.  .  .    ..||||| |||...||| |                      .|.  ||||.|..|.. .... ..||||||||
glleeefeellsvkplleysvallpenkdkNrykdilpydhsRVkl......................degsdYInAsyvdgyssklprkfIatqgPlpn

TIFEFWLMIYQntqryirrcvdggssssphvdreqilqQYFQKIVMLTNFTEANRQKCAVYFPIELN
|.  || |...                           |  . |||||...| .|.||| |.| ||.
tvedFwrmvwe...........................qnvrvIvmLtklvengrekcaqYwplelg

0045450 (Phosphotyrosine protein) phosphatases II 894-1056 8.5e-24 80.3 In-house 34-159 (307) alignment
Range on Protein: 894-1056
Range on HMM: 34-159/307.0
DLHKEFWDLPLNHQEKPMVFGSQTKNRYKTILPNENSRVLLESESseltsllgeikrtssvTASEDLPYINANYI--------KGPDYvSKCYVATQGPL
  ...... .|.. .  .   ...||||| |||....|| | |..                  .||  ||||.|.        .|.|  .. ..||||||
ekllsvtvfllgeysiallpenkdknrykdilpydhtRVklssld................gsledsdYiNAsyvrvpllllldgydl.krkfIatqgPl

PNTIFEFWLMIYQntqryirrcvdggssssphvdreqilqQYFQKIVMLTNFTEANRQKCAVYFPIElNEI
|.|. .|| |...                           |  . |||||...| .|.||| |.| | .| 
petvedFwrmlwe...........................qgvtvivmltelvelgrekcaqywPde.gee

subfamily_Ptp69D_pd Subfamily Ptp69D 894-1000 1.1e-10 36.1 In-house 23-115 (307) alignment
Range on Protein: 894-1000
Range on HMM: 23-115/307.0
DLHKEFWDLPLNHQEKPMVFGSQ----TKNRYKTILPNENSRVLLESesseltsllgeikrtssVTASEDLPYINANYIKGPDYvSKCYVATQGPLPNTI
 | ||.  |. .. .|  ... .     ||||. | . .. || |.                  .. .||  ||||..||| .  .| ..| |.|. .||
glakeyekLeareidkstkvsekkenalknRyedikafDktRvkLkk.................ingkedsdYinasfikgyke.kkkfiaaqdPveati

FEFWLMIYQNT
..|| || .  
gDfWRmiaeqe

0046845 (Phosphotyrosine protein) phosphatases II 895-1056 3.4e-26 87.7 In-house 2-129 (284) alignment
Range on Protein: 895-1056
Range on HMM: 2-129/284.0
LHKEFWDLPLNHQ------EKPMVFGSQTKNRYKTILPNENSRVLLESESSE--LTSllgeikrtssvtasedlpYINANYIKGPD----YVSKCYVATQ
|..||. |. .        .  .    ..||||| |||...||| | |....   ..                  ||||.|..|.|    |..| ..|||
leeefeellsltvklllslsvallpenlsknRykdilpydhsRVklksldgdledsd..................YinAsyvdgydldltyikkkfIatq

GPLPNTIFEFWLMIYQNtqryirrcvdggssssphvdreqilqqYFQKIVMLTNFTEANRQKCAVYFPIElNEI
||||||. .|| |....                             . |||||...| .|.||| |.| | .| 
gPlpntvedFwrmvweq...........................nvrvIVmltelvengrekcaqYwple.gev

subfamily_Urchin-PTP-1_pd Subfamily Urchin-PTP-1 895-1001 4e-11 37.3 In-house 21-112 (315) alignment
Range on Protein: 895-1001
Range on HMM: 21-112/315.0
LHKEFWDLP---LNHQEKPMVFGSQTKNRYKTILPNENSRVLLEsesseltsLlgeikrtssVTASEDLPYINANYIKGPDYvSKCYVATQGPLPNTIFE
. .|| |||     .|        ..||||| ||| ...|| ||        .         .  | |  |||| |||. |   |.|.|.||||. .. .
fseefhdlpdPdiyrqrvaretinfkknryknilPldsarvkle........v.........iddsPdsdyinasyiksvdd.dkayiasqgPlkasvdd

FWLMIYQNTQ
|| |..|.  
fwrmvlqekv

subfamily_Urchin-PTP-4_pd Subfamily Urchin-PTP-4 895-1006 1.4e-10 35.1 In-house 22-118 (392) alignment
Range on Protein: 895-1006
Range on HMM: 22-118/392.0
LHKEFWDLP---LNHQEKPMVFGSQTKNRYKTILPNENSRVLLEsesseltsLlgeikrtssVTASEDLPYINANYIKGPDyVSKCYVATQGPLPNTIFE
. .|| |||   . .|        . ||||| ||| ...|| ||        .         .  . |  |.|| ||.. |   |.|.|.||| . .. .
ffeefhdlpgpdiypqtvaqkeinlkknryknilpydsarvkle........v.........iddipdsdylnasyipsfd.nekayiasqgpnaasldd

FWLMIYQNTQRYIRR
|| |..|.    |  
fwrmvfqenvttiam

subfamily_Urchin-PTP-5_pd Subfamily Urchin-PTP-5 898-1004 2.2e-10 35.2 In-house 31-120 (297) alignment
Range on Protein: 898-1004
Range on HMM: 31-120/297.0
EFWDLPLNHQEKPMVFGSQ---TKNRYKTILPNENSRVLLESESSEltsllgeikrtssvtasEDLPYINANYIKGPDYvskCYVATQGPLPNTIFEFWL
|| .||     .  |   .    |.||| ||| . ||| |..  ..                  |  |.|| ..||  .    ...|| | ..|. .|| 
eflclpeaniqpqtvaekkvnfeksRYkniLPydssRvkLaivndd.................pdsDyvnasfvkgnkh...rlittqmPmkatvadfWa

MIYQNTQRYI
|....    |
mvldeqvsti

0051299 (Phosphotyrosine protein) phosphatases II 903-1054 1.5e-25 85.7 In-house 37-141 (288) alignment
Range on Protein: 903-1054
Range on HMM: 37-141/288.0
PLNHQEKPMVFGSQTKNRYKTILPNENSRVLLEsesseltsllgeikrtsSVTASEDLPYINANYIKGPDYVSKcYVATQGPLPNTIFEFWLMIYQNtqr
| ...   .    ..||||. |||...||| |                  ..  .|.  ||||.||.|...  | ..|||||||||. .|| |....   
pdltlsaallpenleknRysdilpydhsRVkLs.................vldgvegsdYinAsyidgynlkrk.fIatqgPlpntvedFWrmvweq...

yirrcvdggssssphvdreqilqqYFQKIVMLTNFTEANRQKCAVYFPIelN
                          . |||||...| .|.||| |.|   .
........................nvrvIvmltklvelgrekcaqYwpl..g

subfamily_Choan-PTP-2_pd Subfamily Choan-PTP-2 907-1069 6.8e-26 85.8 In-house 12-131 (270) alignment
Range on Protein: 907-1069
Range on HMM: 12-131/270.0
QEKPMVFGSQTKNRYKTILPNENSRVLLesesseltsllgeikrtSSVTASEDLPYINANYIKGPDYVSKCYVATQGPLPNTIFEFWLMIYQNTQryirr
.. | .   .. |||. |||. ..|| |                 ....  .   ||||||..| |  .| |.|..||||.|...|| ||...       
sdlpeaargkklnRyadiLPsPatRvrl.................eeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekv.....

cvdggssssphvdreqilqqyfQKIVMLTNFTEANRQKCAVYFPIELNEIFA-VAAKCEVFQLS
                      . |||.|...| .|.||..|.| | .|  .  . | .|..||
......................taivmttgleEkgrkkCerYWpaepkekvkledgkikvlals

0039614 (Phosphotyrosine protein) phosphatases II 907-1059 5.9e-25 83.8 In-house 48-152 (297) alignment
Range on Protein: 907-1059
Range on HMM: 48-152/297.0
QEKPMVFGSQTKNRYKTILPNENSRVLLESESseltsllgeikrtssvTASEDLPYINANYIKGPDYVSKCYVATQGPLPNTIFEFWLMIYQNtqryirr
..  .   ...||||| |||...||| | .|                    .|. ||||.|..|.|.... ..|||||||.|.  || |....       
ysiallpenkdknrykdilpydhsrvklkped................gvdldsdYinAsyvdgydlltrkfIatqgPlpetvedFwrmvweq.......

cvdggssssphvdreqilqqYFQKIVMLTNFTEANRqKCAVYFPIELNeifaV
                     .. |||||...| .| ||| |.| | .    .
....................gvtvivmLtklvelgr.kcaqywpeegg....t

0047943 (Phosphotyrosine protein) phosphatases II 908-1076 2.2e-25 85.1 In-house 31-150 (273) alignment
Range on Protein: 908-1076
Range on HMM: 31-150/273.0
EKPMVFGSQTKNRYKTILPNENSRVLLESESSEltsllgeikrtssvtasedlpYINANYIKGPDYVSKcYVATQGPLPNTIFEFWLMIYQntqryirrc
.  .    ..||||| |||...||| |....|                      ||||.|..|...  | ..|||||||||. .|| |...         
svallpenkdknrykdilpydhsrvklgdggsd.....................yinAsyvdgynlkrk.fiatqgPlpntvedfwrmvwe.........

vdggssssphvdreqilqQYFQKIVMLTNFTEANRQKCAVYFPIELNEIFAVAAKCEVFQLSAAARDYF
                  |  . |||||...| .|.||| |.| | .|.. .  |  |  ||   .|..
..................qnvrviVmLtelvelgrekcaqYwpleggelsltygkftvtllseetkddy

subfamily_Anemone-PTP-6_pd Subfamily Anemone-PTP-6 910-1002 6.3e-14 46.8 In-house 41-115 (318) alignment
Range on Protein: 910-1002
Range on HMM: 41-115/318.0
PMVFGSQTKNRYKTILPNENSRVLLESESSELTSllgeikrtssvtaseDlpYINANYIKGPDyVSKCYVATQGPLPNTIFEFWLMIYQNTQR
 .    ..||||  ||. ...||.|.  ..| .|               |  ||||||| |    .| |.|.|.|||.|| .|| |...   .
slepvnkaknryanilaydhtrvkLqmlegeegs...............D..yinanyidGyr.rkkayiaaqaPlpetieDfWrmvWeqnsa

0045098 (Phosphotyrosine protein) phosphatases II 911-1004 7.1e-19 63.7 In-house 29-92 (278) alignment
Range on Protein: 911-1004
Range on HMM: 29-92/278.0
MVFGSQTKNRYKTILPNENSRVLlesesseltsllgeikrtssvtasedlPYINANYIKGPdyvSKCYVATQGPLPNTIFEFWLMIYQNTQRYI
.  |.. ||||| |||...|||                             ||||.||.|.   .| ..|||||||.|.  || |....  ..|
lylgnldknRykdilpydhsrVk...........................dYINAsyidgy...pkkfIatqgPlpstvadfwrmlwelgitvi

0040439 (Phosphotyrosine protein) phosphatases II 912-1054 1.6e-19 65.9 In-house 8-103 (249) alignment
Range on Protein: 912-1054
Range on HMM: 8-103/249.0
VFGSQTKNRYKTILPNENSRVLLESesseltsllgeikrtssVTASEDLPYINANYIKGPDYVSKcYVATQGPLPNTIFEFWLMIYQntqryirrcvdgg
   .. ||||. |||...||| |..                 .   ..  ||||.||.|...  . ..|||||||.|.  || |...             
lpenkdknrypdilpydhsrvklsi.................lpglflsdyinAsyidgyyikrr.fiatqgPlpetvedfwrmlwe.............

ssssphvdreqilqQYFQKIVMLTNFTEANRQKCAVYFPIelN
              .  . |||||...| .|.||| |.|   .
..............lgitvivmLtslvelgrekcaqywpl..g

subfamily_PTPN9_pd Subfamily PTPN9 912-1002 5.5e-11 37.0 In-house 39-111 (297) alignment
Range on Protein: 912-1002
Range on HMM: 39-111/297.0
VFGSQTKNRYKTILPNENSRVLLESESSEltsllgeikrT-SsvtaseDlpYINANYIKGPDyVSKCYVATQGPLPNTIFEFWLMIYQNTQR
. .  .||||. .|  ...|| |.... .          . |      |  |||||.. |     |...||||||..|. .||.|....  .
lranleknrytdvlcydetrvvlakvded..........eas......d..yinanfvdGyk.qkkafiatqGplkktvsdfWrmvWeqevl

0037934 (Phosphotyrosine protein) phosphatases II 913-1368 7.9e-37 122.5 In-house 8-242 (243) alignment
Range on Protein: 913-1368
Range on HMM: 8-242/243.0
FGSQTKNRYKTILPNENSRVLLesesseltsllgeikrtssvtasEDLPYINANYIKGPDyvskCYVATQGPLPNTIFE----FWLMIYQNtqryirrcv
  ...||||..|||...||| |                       |.  |||||.|....     . |||||||.|...    || |....         
penlsknrysdilpydhsrvkl.......................egsdyinanliyvtp....rliatqgPlpetveddlasfwrmlwel.........

dggssssphvdreqilqqYFQKIVMLTNFTEANRQKCAVYFPielNEIfaVAAKCEVFQLSAAardyfdryltptfvpdtvvassdaidyeisgrhigve
                   .. |||||...| .|.||| |.|   .|.  .  . .|  ||                                       
..................gitvivmltelvElgrekcaqywp...gev..tygdftvtllsee.....................................

svkvtlegdllealpaqgsffliknvgivRRNGYSVRKLVLLycirvpqSASYHLQKIYCYHYWYPDWPDHHSPRDINTLLdtclhvlnlgkcesefdiy
                               ..| ||.|.|          ..  .. . .||.|  ||||. | ... ||                   
.............................hlddytvrtllle.......nldlddltrlvihyhylpwpdhgvPdspedll...................

ddtrsernahlaaQ---------------RleiyqqdiFNAVQPLPVIHCSAGIGRTGCFTAILNAVRQLRQSlaysltgmltksltsssteeyhnptds
             .               .         .  .   ..|||||.||||.. |..   ..|. .                           
.............dfldevrefieellsll........aldsggpvlVHCsaGvgRtGtliaaylmllllgvd...........................

dssftcntirhishildhrdaeavktppsfdrlpkmpdifvdVLGIVCNLRLQRGG-MVQNSEQYELIHRAICLYL
                                          .. .|. || ||.| .||. .||. ...|.. .|
..........................................leeavkllreqRpgkavqtpsqyrflyeallell

0049772 (Phosphotyrosine protein) phosphatases II 913-1370 5.3e-23 77.7 In-house 44-282 (314) alignment
Range on Protein: 913-1370
Range on HMM: 44-282/314.0
FGSQTKNRYKTILPNEnSRVLLESESSeltsllgeikrtssvtasEDLPYINANYIKGPdyvsKCYVATQGPLPNTIFEF----------WLMI--YQNT
|  ..||||. ||| . .|| | ...                   ..  ||||.|..|.    . ..||||||..|.. |          | |.  ... 
flnrdknryldilpad.nrvilpglpv..................sgsdyinasyvdgf....lkfIatqgpleitvvdfreepvlyyngwrmvlrgdln

QRYirrcvdggssssphvdreqilqqyfqkIVM---------------------LTNFTEANrqkcavyfpiE----------Lneifavaakcevfqls
 |.                           |||                     |..... .                                      
vrd...........................ivmsrdevladelsrLdaAlgKtpllildgng..........neptaadlellk................

aaardyfdryltptfvpdtvvassdaidyeisgrhigvesvK-------Vtlegdllealpaqgsffliknvgivrrngysvrklvllycirvpqsasyh
                                         .       .                                                  
.........................................eelydpelf..................................................

lqKIYCYHYWYPDWPDHHSPrDINTLLDTCLHVLNLgKcesefdiyddtrsernahlaaqrleiyqqdifnaVQPLPVIHCSAGIGRTGCFTAILNAVRQ
  . . ..|.. ..||.. | ... ... . ..... .                                   .   ..||.||.||||.| ..   ...
..erlgikylripvpDgsap.lledfdeflefieea.d..................................kggpvlvHCkaGkgRtgtfvvaaylmkl

LRqslaysltgmltksltsssteeyhnptdsdssftcntirhishildhrdaeavktppsfdrlpkmpdifVDVLGIVCNLRLQRG-----GMVQNSEQY
|.                                                                     |..  ..  .||.|      |.... |||
lg.....................................................................vsleealedvrlkRpinpnpgfieqleqy

ELIHRAICLYLKR
| |..|.. |||.
efilealleylkf

subfamily_PTPN6_pd Subfamily PTPN6 913-1004 4.7e-14 47.1 In-house 52-126 (306) alignment
Range on Protein: 913-1004
Range on HMM: 52-126/306.0
FGSQTKNRYKTILPNENSRVLLEsesseltsllgeikrTSSVTASEdlpYINANYIKGP-DYVSKCYVATQGPLPNTIFEFWLMIYQNTQRYI
   ..|||||.||| ...|| |.                .||. |.   ||||||||.     .|.|.|||| |..|. .|| |..|.  | |
penkeknryknilPfDhtrvilk...............epsvpgsd...yinanyikkevkgsdksyiatqgclettvsdFWrmvwqensrvi

0042113 (Phosphotyrosine protein) phosphatases II 914-1054 3.1e-20 68.1 In-house 8-101 (245) alignment
Range on Protein: 914-1054
Range on HMM: 8-101/245.0
GSQTKNRYKTILPNENSRVLLESesseltsllgeikrtssVTASEDLPYINANYIKGPDYVSKcYVATQGPLPNTIFEFWLMIYQNtqryirrcvdggss
 ...||||. |||....|| | .                 .  ..|..||||.|..|...  | . |||||||.|.  || |....              
enkdknrysdilpydhtrvklsp.................dggdldsdyinasyvdgyritpk.fiatqgPlpetvedfwrmlwel..............

ssphvdreqilqqYFQKIVMLTNFTEANRQKCAVYFPIelN
               . |||||...| .|.||| |.|   .
.............gittivmLteeeelgrvkcaqywpl..g

subfamily_PTPRG_pd Subfamily PTPRG 914-1000 4.6e-12 39.9 In-house 46-115 (563) alignment
Range on Protein: 914-1000
Range on HMM: 46-115/563.0
GSQTKNRYKTILPNENSRVLLESesseltsLLGeikrtssVtaSEDLPYINANYIKGPdYVSKCYVATQGPLPNTIFEFWLMIYQNT
 .. ||||  |.. ..||| |..       | |       .   ..| |||||||.|  . || ..||||||..|.  || ||... 
enkrKnRylnivaydrsRvklsp.......lpg.......k..kkklDYinAnyidGy.qkskafiatqgplkdtfddFWrmiWeqn

subfamily_Anemone-PTP-5_pd Subfamily Anemone-PTP-5 914-1000 7.8e-11 36.6 In-house 47-115 (319) alignment
Range on Protein: 914-1000
Range on HMM: 47-115/319.0
GSQTKNRYKTILPNENSRVLLesesseltsllgeikrtSSVTASEDLPYINANYIKGPDYvSKCYVATQGPLPNTIFEFWLMIYQNT
  ..||||. ||. ...|| |                 |..  .|.  ||||..| | .   . ..|||.|| ||| .|| |.... 
enkkknryqnilaydrtrvvl.................seldgvegsdyinasfidgyqe.rekfiatqaPlentiedfWrmvWeee

subfamily_Sponge-PTP5_pd Subfamily Sponge-PTP5 914-1000 8.6e-11 36.3 In-house 32-99 (283) alignment
Range on Protein: 914-1000
Range on HMM: 32-99/283.0
GSQTKNRYKTILPNENSRVLLESESSeltsllgeikrtssvtasedlPYINANYIK--GPDYVSKCYVATQGPLPNTIFEFWLMIYQNT
  ..|||.. |.| .. || |.|||                       |||| .|     .  .| |...|.|| .|. .|| |.... 
enkrknrnqeivpadqwrvelksesr.....................dyinavfipvsksykqdkkyiiaqsPldrtvvdfWkmvfdek

DSPc_SM00195 915-1004 1.3e-21 72.5 In-house 26-97 (263) alignment
Range on Protein: 915-1004
Range on HMM: 26-97/263.0
SQTKNRYKTILPNENSRVLLESESSEltsllgeikrtssvtasEDLPYINANYIKGPdYVSKCYVATQGPLPNTIFEFWLMIYQNTQRYI
...||||| |||....|| |..| ..                 |.  |||||||||.   .| |.|||||||.|. .|| |....  ..|
nksknRyknilpydhtrVklkkeekk.................egsdYINAnyikga.nkkkkyIatQgPlpstvedFWrmvweekvkii

PTPc_SM00194 915-1004 1.3e-21 72.5 In-house 26-97 (263) alignment
Range on Protein: 915-1004
Range on HMM: 26-97/263.0
SQTKNRYKTILPNENSRVLLESESSEltsllgeikrtssvtasEDLPYINANYIKGPdYVSKCYVATQGPLPNTIFEFWLMIYQNTQRYI
...||||| |||....|| |..| ..                 |.  |||||||||.   .| |.|||||||.|. .|| |....  ..|
nksknRyknilpydhtrVklkkeekk.................egsdYINAnyikga.nkkkkyIatQgPlpstvedFWrmvweekvkii

subfamily_Fungi-PTP1_pd Subfamily Fungi-PTP1 915-1002 3.7e-17 57.1 In-house 47-130 (350) alignment
Range on Protein: 915-1002
Range on HMM: 47-130/350.0
SQTKNRYKTILPNENSRVLLE-SESSEltsllgeiKRTSSVTASEDlpYINANYIKGP----DYVSKC-YVATQGPLPNTIFEFWLMIYQNTQR
. .||||| ||| | ||| |. |  |         .     . ..|  ||||||.| .    .  ..  |.|||.|||.|. .|. .|..|  .
lfaknrYknilPYehsrvkLkkslkss........dakkhslstnD..YinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvk

subfamily_Fungi-PTP2_pd Subfamily Fungi-PTP2 915-1001 1.1e-14 48.5 In-house 48-132 (349) alignment
Range on Protein: 915-1001
Range on HMM: 48-132/349.0
SQTKNRYKTILPNENSRVLLESESSelTSLLGEIKrTSSVTASEDLPYINANYIKGPDY-VSKCYVATQGPLPNTIFEFWLMIYQNTQ
. .||||| ||| | ||| |.      .|   .   ||   ..    ||||||.| . . | | |.||| ||| |. .|. .|  |  
lfaknrykdilPyehsrvklkkslk..sskvikas.tsesdsgklddyinanylkltrisvekkyiatqaPlPstvddfykvillngv

subfamily_PTPRB_pd Subfamily PTPRB 915-1004 1.1e-14 49.2 In-house 51-122 (293) alignment
Range on Protein: 915-1004
Range on HMM: 51-122/293.0
SQTKNRYKTILPNENSRVLLESESSEltsllgeikrtssvtasEDLPYINANYIKGPDyVSKCYVATQGPLPNTIFEFWLMIYQNTQRYI
 ..||||. ||| ..||| |.. ..|                 ..  |||||||.|     . ..|||||||.|. .|| |....  . |
nraknrytnilpydhsrvkLaalkde.................sgsDYinanyipgyn.sprefiatqGPlpetvddfWrmvwekkssii

subfamily_Urchin-PTPRB-like_pd Subfamily Urchin-PTPRB-like 915-1003 1.1e-12 42.6 In-house 47-117 (288) alignment
Range on Protein: 915-1003
Range on HMM: 47-117/288.0
SQTKNRYKTILPNENSRVLLESESSEltsllgeikrtssvtasEDLPYINANYIKGpDYVSKCYVATQGPLPNTIFEFWLMIYQNTQRY
 ..||||. ||| .  || |.    |                 ..  ||||.||.| .  .| |.||||||..|. .|| ..|.|    
nakknRyrnilpyDekrvklkkleee.................agaDYinasyidg.ekkkkkyiatqgPladtvndfWelvyenktst

subfamily_Sponge-PTP11_pd Subfamily Sponge-PTP11 915-1002 5.9e-09 30.2 In-house 46-117 (290) alignment
Range on Protein: 915-1002
Range on HMM: 46-117/290.0
SQTKNRYKTILPNENSRVLLESESSEltsllgeikrtSSVTASedlpYINANYIKGPDYvSKCYVATQGPLPNTIFEFWLMIYQNTQR
....||...|..... |. |   |..              | .    |||| ||||    .| |.|||||..||. .|| .|.|.   
nkllnRfanivvyddnritLrpisgh...........kDCtne....yinAcyikgyke.kkqyiatqgpvsntlvdFWkliwqekvt

subfamily_Urchin-PTP-3_pd Subfamily Urchin-PTP-3 915-1055 7.1e-09 30.2 In-house 48-142 (325) alignment
Range on Protein: 915-1055
Range on HMM: 48-142/325.0
SQTKNRYKTILPNENSRVLLESESSEltsllgeikrtS-SvtaseDlpYINANYIKGpDYVSKCYVATQGPLPNTIFEFWLMIYQNTqryirrcvdggss
 . |||.| ... ..||| ||.   .           . |     |  ||||.|..  |   . ..|.| ||..|| ..| ....               
nkaknrfknvvaldksrvvletkkdd...........pss.....d..yinasylrd.dkkkdvflaaqaPltatindlWrlvldWr.............

ssphvdreqilqqyfQKIVMLTNFTEANRQKCAVYFPIELNE
                 .|...|  . . ..||||.| |. .
...............csvvvvlneldlgkdrcavywpkemgk

subfamily_egg_pd Subfamily egg 915-1050 8.2e-09 29.6 In-house 40-128 (307) alignment
Range on Protein: 915-1050
Range on HMM: 40-128/307.0
SQTKNRYKTILPNENSRVLLESESSELTSllgeikrtssvtasedlPYINANYIKGPDYVSKcYVATQGPLPNTIFEFWLMIYQNTQRYIRRCVDGGSSs
 ..| | | .  .. ||| || .    .                   .| ||..||   . . .. .| || ||  .|| |..|.  .||        | 
nlekarskrvhckdssrvklelrrGqyld.................dfihanrvkGkpllne.filaqaplkntvddfwrmvfqeevqyivmltsrkes.

sphvdreqilqqyfqkivmltnfteanrQKCAVYFP
                            ..|  |.|
............................erceyywp

0041856 (Phosphotyrosine protein) phosphatases II 916-1369 2e-28 94.6 In-house 2-172 (182) alignment
Range on Protein: 916-1369
Range on HMM: 2-172/182.0
QTKNRYKTILPNENSRvllesesseltsllgeikrtssvtaseDLPYINANYIKGPDYVSKcYVATQGPLPNTIFEFWLMIYQNTQRYIRRCVdggssss
..||||. |||...||                           || |||||.. |. . .. ..||||||..|. .|. |....  ..| ..        
ldknrysdilpydhsr...........................dldyInanlylgslpatr.fiatqgpllstvadflrmlkelgittivnlt.......

phvdreqilqqyfqkivmltnfteanrqkCAVYFPielneifavaakcevfqlsaaardyfdryltptfvpdtvvassdaidyeisgrhigvesvkvtle
                             .  |.|                                                                 
.............................eelywp.................................................................

gdllealpaqgsffliknvgivrrngysvrklvllycirvpqsasyHLQKIYCYHYWYPDWPDHHSPRdINTLLDTCLHVLNlgkcesEfdiyddtrser
                                               | . . ..|.|  ||||. |  ...||| .  ||.      |           
..............................................ellerlgiqylylpwpDhgvpd.ldelldfieevle......e...........

nahlaaqrleiyqqdifnavQPLPVIHCSAGIGRTGCFTAILNAVRQlRQSlaysltgmltksltsssteeyhnptdsdssftcntirhishildhrdae
                    .   ..|||||.||||.. |.    .. . |                                                 
....................ggpvlVHCsaGvgRtgtlvaaylmkkl.gvs.................................................

avktppsfdrlpkmpdifvdVLGIVCNLRLQRGGMVQNSEQYELIHRAICLYLK
                    .  .|. .| .| |||.. .|| ....|....|.
....................leeavklvrsrRpgmvitpnqyfflqlallelll

Y_phosphatase Protein-tyrosine phosphatase 916-1004 1.3e-18 62.6 Pfam-A 2-70 (235) alignment
Range on Protein: 916-1004
Range on HMM: 2-70/235.0
QTKNRYKTILPNENSRVLLesesseltsllgeikrtSSVTASEDlpYINANYIKGPDyVSKCYVATQGPLPNTIFEFWLMIYQNTQRYI
..|||||.||| ...|| |                 .. . ..|  ||||||.|| .  .| ..||||||..|| .|| |..|.  ..|
kkknRykdilpydktrvkl.................kgsegpsd..YInAnyvkgyk.ekkkfIatQgPlkstiedFWrmvwqekvkvi

Y_phosphatase Protein-tyrosine phosphatase 916-1004 1.3e-18 62.6 In-house 2-70 (235) alignment
Range on Protein: 916-1004
Range on HMM: 2-70/235.0
QTKNRYKTILPNENSRVLLesesseltsllgeikrtSSVTASEDlpYINANYIKGPDyVSKCYVATQGPLPNTIFEFWLMIYQNTQRYI
..|||||.||| ...|| |                 .. . ..|  ||||||.|| .  .| ..||||||..|| .|| |..|.  ..|
kkknRykdilpydktrvkl.................kgsegpsd..YInAnyvkgyk.ekkkfIatQgPlkstiedFWrmvwqekvkvi

subfamily_PTPN12_pd Subfamily PTPN12 916-999 2.2e-16 54.6 In-house 41-106 (290) alignment
Range on Protein: 916-999
Range on HMM: 41-106/290.0
QTKNRYKTILPNENSRVLLESESSELtsllgeikrtssvtaseDLPYINANYIKGPDyVSKCYVATQGPLPNTIFEFWLMIYQN
..||||| ||| ..||| |. ...|                  .  |||||.|||..  .. |.|.|||||.|. .|| ||.. 
vkknrykDilPydksrvelskieeee.................gsdYinanfikgve.gkleyiaaqgPLpktlddfWrmiwek

subfamily_Choan-PTP-1_pd Subfamily Choan-PTP-1 916-1003 5.1e-13 43.8 In-house 42-111 (281) alignment
Range on Protein: 916-1003
Range on HMM: 42-111/281.0
QTKNRYKTILPNENSRVLLESESSELtsllgeikrtssvtaseDLPYINANYIKGPDyVSKCYVATQGPLPNTIFEFWLMIYQNTQRY
..||||. |   ...|| .. ....                  .  |||||...| .   | |.|||||.|... .|| |..... . 
vlknrYsnivaYDatrvkvtpneenk.................ntDYinanfvpgyk.gekeyiatqgPvPaslvafWqmvweqkvsa

subfamily_Nvec-PTP-2_pd Subfamily Nvec-PTP-2 916-1002 1.9e-11 38.7 In-house 10-78 (250) alignment
Range on Protein: 916-1002
Range on HMM: 10-78/250.0
QTKNRYKTILPNENSRVLLESESSEltsllgeikrtssvtasEDLPYINANYIKGPDYVsKCYVATQGPLPNTIFEFWLMIYQNTQR
. ||||  |.. ..|||.||.|...                 ..  |||| ...| |   | ..||||||..|| .|| |....   
keknryadiialdssrvvLekekgd.................kesdyinasflhgyder.kafiatqgPlqatiedfWrmvleeksg

subfamily_PTPN13_pd Subfamily PTPN13 916-1003 4.1e-11 37.7 In-house 38-104 (273) alignment
Range on Protein: 916-1003
Range on HMM: 38-104/273.0
QTKNRYKTILPNENSRVLLESESSeltsllgeikrtssvtasedlpYINANYIKGP-DYVSKCYVATQGPLPNTIFEFWLMIYQNTQRY
..||||. .|| ...|| |..|..                      ||||..|| | .     |.|.|||||.|. .||.|... . . 
kdknryrnvlPydetrvklgdegg......................yinaslikvpvgkdeyeyiacqGPlPetvkdfwqmvweqkaev

subfamily_Sponge-PTP10_pd Subfamily Sponge-PTP10 916-1001 1.6e-10 35.4 In-house 48-111 (287) alignment
Range on Protein: 916-1001
Range on HMM: 48-111/287.0
QTKNRYKTILPNENSRVLLEsesseltsllgeikrtssvtaSEDLPYINANYIKGPDyVSKCYVATQGPLPNTIFEFWLMIYQNTQ
. |||.. ||. .| ||||.                      |.  |||| .|.|    .| ......|. ||. .|| .| ..  
kdknRltqilvpdnyrvllk.....................gehpdyinavfidgyk.ekkafiiaesPmfntarnfWkliddrnv

subfamily_Urchin-PTP-6_pd Subfamily Urchin-PTP-6 916-1000 1.1e-09 31.9 In-house 44-110 (515) alignment
Range on Protein: 916-1000
Range on HMM: 44-110/515.0
QTKNRYKTILPNENSRVLLESesseltsllgeikrtssVTASEDLPYINANYIKGPDyVSKCYVATQGPLPNTIFEFWLMIYQNT
 .||||| ||| ...|| ||                  .  . .  |.|| ||.. |   |.|.|.|||.. .. .|| ...|. 
fkknryknilPydsvrvklev.................indnPhsdyfnasyipsfd.ndkayiasqgPnkasvddfWrlvlqen

subfamily_Anemone-PTP-4_pd Subfamily Anemone-PTP-4 916-1000 2.2e-09 31.9 In-house 4-69 (237) alignment
Range on Protein: 916-1000
Range on HMM: 4-69/237.0
QTKNRYKTILPNENSRVLLESESSEltsllgeikrtssvtasedLPYINANYIKGPDYVSKCYVATQGPLPNTIFEFWLMIYQNT
. ||||  |   . |||.|.   |.                     ||||.|.|| |   | |.|.|||| ..  .|| |..|. 
kiknrygnivaydhsrvvlkgagsg...................sdyinatylkgfdgtpkkyiaaqgplesscddfwqmvwqek

subfamily_Choan-PTP-3_pd Subfamily Choan-PTP-3 916-1000 3.7e-09 30.8 In-house 39-104 (287) alignment
Range on Protein: 916-1000
Range on HMM: 39-104/287.0
QTKNRYKTILPNENSRVLLESESsEltslLGeikrtSSvtasedlpYINANYIKGPDyVSKCYVATQGPLPNTIFEFWLMIYQNT
  ||||  .|| ...||||  |. |    ||     |.        ||||||. .     . ..|.|||.. |. .|| ..... 
vkknryadvlPiddtrvllsaeg.e....lG.....sd........yinanyvasyt.ddeafiaaqgPiaatvrdfwravletr

subfamily_Urchin-PTP-7_pd Subfamily Urchin-PTP-7 916-999 1.2e-08 29.3 In-house 50-115 (315) alignment
Range on Protein: 916-999
Range on HMM: 50-115/315.0
QTKNRYKTILPNENSRVLLEsesseltslLGEIKRTSSvtasedlpYINANYIKGPDYVsKCYVATQGPLPNTIFEFWLMIYQN
. ||||  |.. ..||| |          | | .  |         |.|||.|.| ..  . |.|.|||..... .|| .....
kqknryiniiaydksrvqlp.........llendphsd........yvnanfidGynkk.rryiaaqgpnvasvkdfwrlvfee

subfamily_Sponge-PTP1_pd Subfamily Sponge-PTP1 916-1000 1.1e-06 22.8 In-house 34-96 (267) alignment
Range on Protein: 916-1000
Range on HMM: 34-96/267.0
QTKNRYKTILPNENSRVLLESESSEltsllgeikrtssvtasedlpYINANYIKGPdYVSKCYVATQGPLPNTIFEFWLMIYQNT
| .||.   || ...|| |  .  |                     |||| |..|  .  . ...||.|| ||| .|. .| .. 
qernrlddnlpyddtrvilrtkeee.....................yinasyvegy.ktknafivtqdplkntitdfltvihdqk

subfamily_PTPN14_pd Subfamily PTPN14 916-1002 1.2e-06 22.7 In-house 50-119 (300) alignment
Range on Protein: 916-1002
Range on HMM: 50-119/300.0
QTKNRYKTILPNENSRVLLESEsseltsllgeiKRT--SsvtasedlpYINANYIKGPDY-VSKCYVATQGPLPNTIFEFWLMIYQNTQR
. |||.| .|| |..|| | .            | .            ||||  || .    .. |...||||..|. .|| |....  .
aeknrfkdvlPyednrvelspt...........kenstg.........yinassikvsvggkersyivaqgPleltvqdfWqmvWeqgvq

subfamily_Anemone-PTP-1_pd Subfamily Anemone-PTP-1 916-1001 1.5e-06 22.5 In-house 9-77 (239) alignment
Range on Protein: 916-1001
Range on HMM: 9-77/239.0
QTKNRYKTILPNENSRVLLESESSELTSllgeikrtssvtasEdlpYINANYIKGPDYVSKCYVATQGPLPNTIFEFWLMIYQNTQ
..||||  |.  . |||.||  | .  |              .   ||||.|..  |   |.|.|||| .  .  .|| |..|. .
kaknryanivtydhsrvvleklsndphs..............d...yinasylrdydgspkayiatqgcveissgdfwrmmwqerr

subfamily_Nvec-PTP-1_pd Subfamily Nvec-PTP-1 916-1001 1.6e-06 22.5 In-house 8-76 (239) alignment
Range on Protein: 916-1001
Range on HMM: 8-76/239.0
QTKNRYKTILPNENSRVLLESESSELTSllgeikrtssvtasEdlpYINANYIKGPDYVSKCYVATQGPLPNTIFEFWLMIYQNTQ
..||||  |.  . |||.||  | .  |              .   ||||.|..  |   |.|.|||| .  .  .|| |..|. .
kaknryanivtydhsrvvleklsndphs..............d...yinasylrdydgspkayiatqgcveissgdfwrmmwqerr

subfamily_Sponge-PTP6_pd Subfamily Sponge-PTP6 916-1000 2.9e-06 21.0 In-house 49-115 (439) alignment
Range on Protein: 916-1000
Range on HMM: 49-115/439.0
QTKNRYKTILPNENSRVLLEsesseltsllgEikrTSSVTASEdlpYINANYIKGpDYVSKCYVATQGPLPNTIFEFWLMIYQNT
||||||| . . . .|| |.           |   .  |  |    |||||||||  |  | |.|||||  .|  .|| ..... 
qtknrykdvgafdhtrvtlq...........e...ipgvphsh...yinanyikG.yyddklyiatqgpkkettddfwrlviekk

subfamily_PTPN23_pd Subfamily PTPN23 917-1004 4.9e-14 46.8 In-house 45-111 (288) alignment
Range on Protein: 917-1004
Range on HMM: 45-111/288.0
TKNRYKTILPNENSRVLLEsesseltsllgeikrtssvtASEDlPYINANYIKGPDYVSKCYVATQGPLPNTIFEFWLMIYQNTQRYI
.|||.. ||| ...|| |.                     |.|  |||| ..|.   .. ...|||.||..|. .||||.|..  . |
eknrsrdilPyDhnRvklr....................gskD.DYinAsfvkdlspgcPdfiatqaPlqstlnDFWlmvyeqkssvi

subfamily_Urchin-PTPRA_pd Subfamily Urchin-PTPRA 917-1007 5.6e-11 37.3 In-house 63-136 (319) alignment
Range on Protein: 917-1007
Range on HMM: 63-136/319.0
TKNRYKTILPNENSRVLLEsesseltsllgeikRTSSVTASEdlpYINANYIKGPDYvSKCYVATQGPLPNTIFEFWLMIYQ-NTQRYIRRC
 |||.  ||. ....| ||              |.  .  |.   |||| ...|     . |.|.||||.||. .|| ||.. |.  ..   
dknriinilafdknvvkle..............rliGeefsd...yinasfvtGyqr.kdkyiaaqGPldntladfWrmiweyncstivllt

subfamily_ptpA1_pd Subfamily ptpA1 917-1004 1e-10 35.9 In-house 49-117 (418) alignment
Range on Protein: 917-1004
Range on HMM: 49-117/418.0
TKNRYKTILPNENSRVLLesesseltsllgeiKRtssVTASEDLPYINANYIKGPdYvSKCYVATQGPLPNTIFEFWLMIYQNTQRYI
.||||  ||| . .|| |              |.   .   |   ||||||| |  |  | ...||||||||| .|| |...|  | |
sknrytnilpvnhtrvql..............kk...iqdkegsdyinanyidga.y.pkqfictqgplpntiadfwrmvwenrcrii

subfamily_PTPRK_pd Subfamily PTPRK 917-1000 1.7e-09 31.9 In-house 45-110 (314) alignment
Range on Protein: 917-1000
Range on HMM: 45-110/314.0
TKNRYKTILPNENSRVLLESesseltsLLGEikrTSSvtasEdlpYINANYIKGPDyVSKCYVATQGPLPNTIFEFWLMIYQNT
.|||.. ||. ..||| | .       . |.   .||    .   ||||..| .    .. ...|||||..|. .|| ..|.. 
eknrsgdilaydrsrvflit.......idgd...pss....d...yinaalidsyk.rpaafivtqgPlqetvkdfWrlvyden

subfamily_PTPRN_pd Subfamily PTPRN 917-1000 5.9e-09 30.0 In-house 58-124 (297) alignment
Range on Protein: 917-1000
Range on HMM: 58-124/297.0
TKNRYKTILPNENSRVLLESESSEltsllgeikrtssvtasEDLPYINANYIKGPDYVSKCYVATQGPLPNTIFEFWLMIYQNT
.|||.|..|| ..||| |..|.|.                 |.  ||||  |   |  . .|.||||||..|. .|| |.... 
kknrskavlpydhsrvklkeeasa.................eksdyinasaildhdprapayiatqgplastvadfwqmvweqG

subfamily_Cele-PTP-17_pd Subfamily Cele-PTP-17 917-997 2.6e-07 24.5 In-house 39-106 (347) alignment
Range on Protein: 917-997
Range on HMM: 39-106/347.0
TKNRYKTILPNENSRVLLESESSELTsllgeikRTSSVTAsedlpYINANYIKGpDYVSKCYVATQGPLPNTIFEFWLMIY
.||| |    ....||.|  | |. .       |.  | .     |||| .||  |  || |. || |||.|. .|| |..
sknrskdvklidatrvvlspekskns.......raddvet.....yinashikf.dnaskeyiltqyplpdtvrdfwkmvs

subfamily_CG7180_pd Subfamily CG7180 917-1001 2.2e-06 21.6 In-house 44-110 (296) alignment
Range on Protein: 917-1001
Range on HMM: 44-110/296.0
TKNRYKTILPNENSRVLLESesseltsLLGEikrtssvtASEDlpYINANYIKGPdYVSKCYVATQGPLPNTIFEFWLMIYQNTQ
 |||. ...| .. ||.||.       | ||        ...|  |||| |. .     | |. |..|  .|. ||| ..|..  
eknrdvkvvPyDynRvvLek.......ldGe........eksd..Yinavyvdsf.lkkkeyivteapkketvdefWrlvydeei

subfamily_Cele-PTP-15_pd Subfamily Cele-PTP-15 948-1004 1.4e-09 32.4 In-house 47-103 (285) alignment
Range on Protein: 948-1004
Range on HMM: 47-103/285.0
IKRTSSVTASEDLPYINANYIKGPDYVSKCYVATQGPLPNTIFEFWLMIYQNTQRYI
|. |  |    |  || |.... |      |..||||||.|. .|| ||||.   |.
ieetrvvlknhdrdyihaswmrmpgkdqstyittqgplpetlsdfwhmiyqekiayv

subfamily_Sponge-PTP8_pd Subfamily Sponge-PTP8 953-1004 2.8e-11 38.1 In-house 64-117 (305) alignment
Range on Protein: 953-1004
Range on HMM: 64-117/305.0
SVTASED---LPYINANYIKGPDyVSKCYVATQGPLPNTIFEFWLMIYQNTQRYI
 .|..|.     ||||.|..| .  .|.|...||||.||. .|| .|..   . |
iltekeslddsdyinasyvdgyk.rkkkyivaqgPlkntvadfWrliveekvsti

subfamily_CG42327_pd Subfamily CG42327 955-1005 2.3e-07 24.8 In-house 51-101 (319) alignment
Range on Protein: 955-1005
Range on HMM: 51-101/319.0
TASEDLPYINANYIKGPDYVSKCYVATQGPLPNTIFEFWLMIYQNTQRYIR
.  .   |..|.|..|.|     |.|.| .| ..  .|| .....  | | 
gdddkdeyldasyvrGyddapnsyiaaqvsledsssdfwrtvweqqsrviv

subfamily_Choan-PTP-4_pd Subfamily Choan-PTP-4 955-1004 5e-07 23.9 In-house 56-104 (297) alignment
Range on Protein: 955-1004
Range on HMM: 56-104/297.0
TASEDlpYINANYIKGPDYVSK-CYVATQGPLPNTIFEFWLMIYQNTQRYI
 . .|  ||||.|.  ||  ..  |. .|||| .|. .|| .....  | |
iterd..yinadyvvfpdeeadlkyilaqGplsatvddfwtlvaeqdvrvi

subfamily_Urchin-PTP-8_pd Subfamily Urchin-PTP-8 956-1007 6.5e-11 37.2 In-house 49-100 (284) alignment
Range on Protein: 956-1007
Range on HMM: 49-100/284.0
ASEDLPYINANYIKGPDYvSKCYVATQGPLPNTIFEFWLMIYQ-NTQRYIRRC
  |   |||| .|.|     . |.||||||.||. .|| ||.. |.  ..   
GeefsdyinasfitGyqr.kdkyiatqGPldntladfWrmiweyncstivllt

subfamily_Cele-PTP-14_pd Subfamily Cele-PTP-14 957-1004 9.1e-09 29.3 In-house 76-122 (310) alignment
Range on Protein: 957-1004
Range on HMM: 76-122/310.0
SEDLPYINANYIKGpDYVSKCYVATQGPLPNTIFEFWLMIYQNTQRYI
|    || |||.|  .|. . .. .||||  || .|| ||.|.    |
sryedyihanyvkt.nylrstficsqgplqhtiidfwrmifqeraesi

subfamily_PTPN3_pd Subfamily PTPN3 957-1004 1.3e-08 29.1 In-house 63-112 (280) alignment
Range on Protein: 957-1004
Range on HMM: 63-112/280.0
SEDlPYINANYIK--GPD-YVSKCYVATQGPLPNTIFEFWLMIYQNTQRYI
||   ||||||..   |   ... |.||||||..|  .|| |..... . |
set.dyinanyvnmeipstglvnryiatqGPlaktatdfWqmvweqkssli

0044763 (Phosphotyrosine protein) phosphatases II 958-1365 2.5e-15 52.0 In-house 16-168 (178) alignment
Range on Protein: 958-1365
Range on HMM: 16-168/178.0
EDLPYINANYIKGPdyvskCYVATQGPlpntifefwlmiyqntqryirrcvdggsssspHVDREQILQQYFQKIVMLTNFTEANRQKCAVYFPIELNeif
|  .||||..| .       |.....|                                  |.|.. .. .. ||.||. .| ...||  |.| | .   
ersdyinaseilpg.....lylgslpp................................addlellkelgithivnlteelelgflkcdpywpeeag...

avaakcevfqlsaaardyfdryltptfvpdtvvassdaidyeisgrhigvesvkvtlegdllealpaqgsffliknvgivrrngysvrklvllycirvpq
                                                                                                    
....................................................................................................

sasyhlqkiycYHYWYPDWPDHHSPRdINTLLDTCLHV----LnlgkcesefdiyddtrsernahlaaqrleiyqqdifNAVQPLPVIHCSAGIGRTGCF
           ..| .  .|||. |  .   .. ...     |                                    .  .   ..|||||.||.|..
...........iqylhipipDhgvpd.llehflefvefieeal....................................dekggpvlVHCsaGvgRsgtl

TAI-LNAVRQlrqslaysltgmltksltsssteeyhnptdsdssftcntirhishildhrdaeavktppsfdrlpkmpdifVDVLGIVCNLRLQRGgMVQ
 |. |  ...                                                                       ...  ..  .| .|  .|.
vaaylmkklg.......................................................................lsleeaielvrerRp.ivp

NSEQYELIHRAIC
| .|.. ...   
npgqlrqLyefel

subfamily_Cele-PTP-13_pd Subfamily Cele-PTP-13 958-1001 5.6e-07 23.5 In-house 64-106 (281) alignment
Range on Protein: 958-1001
Range on HMM: 64-106/281.0
EDLPYINANYIKGPdYVSKCYVATQGPLPNTIFEFWLMIYQNTQ
.   || ||||. | .. . |. ||||  .|  .|| ||.|.  
nstdyihanyirsp.flkrgyiltqgpkketradfwrmiwqent

0046846 (Phosphotyrosine protein) phosphatases II 958-1005 7.3e-06 21.4 In-house 10-52 (176) alignment
Range on Protein: 958-1005
Range on HMM: 10-52/176.0
EDLPYINANYIKGPdyvskCYVATQGPLPNTIFEFWLMIYQNTQRYIR
.|| |||||.| |.     ...|||||||.|. .|. |....  ... 
ldldyinanlilgs.....rpiatqgplprtladflemlkelgitavv

0043147 (Phosphotyrosine protein) phosphatases II 959-1259 6.6e-18 60.5 In-house 4-123 (172) alignment
Range on Protein: 959-1259
Range on HMM: 4-123/172.0
DLPYINANYIKGPDYVSKcYVATQGPLPNTIFEFWLMIYQNTQRYIRRCVDGgssssphvdreqilqqyfqkivmltnfteanrqkcavyfpielneifa
.  ||||.|....    . ..||||||.||. .|| |....  ..| .. .                                                 
gsdyinasyldlyyipdr.fiatqgplrntladfwrmlkelgithivnltel................................................

vaakcevfqlsaaardyfdryltptfvpdtvvassdaidyeisgrhigvesvkvtlegdllealpaqgsffliknvgivrrngysvrklvllycirvpqS
                                                                                                    
...................................................................................................l

ASYHLQKIYCYHYWYPDWPDHHSPrDINTLLDTCLHVLNLGkCESEfdiyddtrsernahlaaqrleiyqqdifnavQPLPVIHCSAGIGRTGCFTAILN
  . | . . ..|.|  ||||. | ... ||...  . .|  ..|.                               .   ..|||||.||||.. |.. 
ydpellerlgiqylylpwpDhgvp.llellleflefidell.alsp...............................ggpvlVHCsaGvgRtgtlvaayl

A
 
m

subfamily_Sponge-PTP9_pd Subfamily Sponge-PTP9 959-1005 9.5e-08 26.1 In-house 69-114 (301) alignment
Range on Protein: 959-1005
Range on HMM: 69-114/301.0
DLPYINANYIKGPDYvSKCYVATQGPLPNTIFEFWLMIYQNTQRYIR
   ||||.||.|    .| ..|.|||. .|. .|| .|.|. .  | 
qreyinasyidgyse.kkkfiaaqgpmkktlvdfWrliwqekpvsiv

subfamily_Cele-PTP-10_pd Subfamily Cele-PTP-10 959-1002 2.1e-07 24.9 In-house 79-122 (305) alignment
Range on Protein: 959-1002
Range on HMM: 79-122/305.0
DLPYINANYIKGPDYVSKCYVATQGPLPNTIFEFWLMIYQNTQR
   || |||.  |    | ....|||| .|| ||| |. ||   
psdyihanyvgcpmipekrficaqgpldqtidefwwmviqnkve

0051082 (Phosphotyrosine protein) phosphatases II 961-1260 6.5e-13 44.0 In-house 4-116 (151) alignment
Range on Protein: 961-1260
Range on HMM: 4-116/151.0
PYINANYIKGPdyvskcYVATQGPLPntifefwlmiyqntqryirrcvdggssssphVDREQILQQYFQKIVMLTNFTEANrqKCAVYFPIELneifava
.|||..|. |       . ...|||.                                . |.. .. .. ||.|.. .| .  .|. |.| .        
dyinfsyvtgg......lyrsggpla...............................dflellkelgiktivnlrseeerg..ycpeylpelg.......

akcevfqlsaaardyfdryltptfvpdtvvassdaidyeisgrhigvesvkvtlegdllealpaqgsffliknvgivrrngysvrklvllycirvpqsas
                                                                                                    
....................................................................................................

yhlqkIYCYHYWYPDWPDHHsprdintlldtclhvlnlgkcesefdiyddtrsernA----HLAAQRLEIYQQdifnaV-QPLPVIHCSAGIGRTGCFTA
     |  .|....||||.                                          . ... ||....       .   ..|||||.||||.. |
.....ievlhipildwpdpg....................................lplsfdavleflellld.....kkngpvlvHCsaGkgRTGtlva

ILNAV
..   
lylml

subfamily_Cele-PTP-18_pd Subfamily Cele-PTP-18 961-1004 8.2e-06 19.7 In-house 74-116 (305) alignment
Range on Protein: 961-1004
Range on HMM: 74-116/305.0
PYINANYIKGPDYvSKCYVATQGPLPNTIFEFWLMIYQNTQRYI
 || |||.  |   .| .. || || .|  .|| | .|.   .|
eyihanyvstptn.pkrfictqaplektcadfwymclqdkveai

0036282 (Phosphotyrosine protein) phosphatases II 962-1361 1.3e-19 66.0 In-house 4-163 (174) alignment
Range on Protein: 962-1361
Range on HMM: 4-163/174.0
YINANYIKGpDYVSKCYVATQGPLPntifefwlmiyqntqryirrcvdggssssphvDREQILQQYFQKIVMLTNFTEANRQKCAVYFPIelneifavaa
||||.....  |... ..|.||||.                                . |.. .. .. .|||..  | .. ||  |.|           
yinaspldl.syitprliagqgpla................................fwemlkelgittvvmlleekelglykcinywpe..........

kcevfqlsaaardyfdryltptfvpdtvvassdaidyeisgrhigvesvkvtlegdllealpaqgsffliknvgivrrngysvrklvllycirvpqsaSY
                                                                                                   .
..................................................................................................lr

HLQKIYCYHYWYPDWPDHHSPRDINtLLDTCLHVLNLGkcesefdiyddtrsernahlaaqrleiyqqdifnA--VQPLPVIHCSAGIGRTGCFTAILNA
.  . . ..|.|  ||||. | .   ||. .  | .                                    .   .   ..|||||.||||.. |..  
edlerlgiqylylpwpDhgvpdlsi.llefvkfveeal..................................sedpggpvlVHCsaGvgRtGtlvaaylm

VRQLRQSLAYSltgmltksltsssteeyhnptdsdssftcntirhishildhrdaeavktppsfdrlpkmpdifvdvLGIVCNLRLQRGGMVQNSEQYEL
 |.|..||                                                                     | .|  |||||.||||. .||. 
lrglleslvda..................................................................ldlvrelRlqrpgmvqtpsQyrf

IH
..
ly

0046846 (Phosphotyrosine protein) phosphatases II 1009-1370 5.5e-19 64.1 In-house 29-175 (176) alignment
Range on Protein: 1009-1370
Range on HMM: 29-175/176.0
DGGSSSSPHVDREQILQQYFQKIVMLTNFTEANRQKCAVYFPIELNEIFavaakcevfqlsaaardyfdryltptfvpdtvvassdaidyeisgrhigve
.|.  ..   . |..... .. .|.||. .| .| ||. |.|.. .. .                                                   
qgplprtladflemlkelgitavvnlteevelgrlkcpnywpeleklgi...................................................

svkvtlegdllealpaqgsffliknvgivrrngysvrklvllycirvpqsasyhlqkiycyHYWYPDWPDHHSPRDiNTLLDTCLHVLNLGK---Cesef
                                                             .|.. .||||. | . . ||. .  . .  |   .    
.............................................................qylhlpwpDhgvpdl.elllellefirealkeggp....

diyddtrsernahlaaqrleiyqqdifnavqplPVIHCSAGIGRTGCFTAILNAvrqlrqslaysltgmltksltsssteeyhnptdsdssftcntirhi
                                  ..||||||||||.. |..                                                
.................................vlVHCsaGigRtgtlvaayll..............................................

shildhrdaeavktppsfdrlpkMPDIFVDVLGIVCNLRLQRG-GMVQNSEQYELIHRAICLYLKR
                       . . ...|. ... .| ||  |.||. |||. ......|.||.
.......................elekglsveealalvreqRplgavqtpeQyrflyefellllkk

0049260 (Phosphotyrosine protein) phosphatases II 1015-1258 1.1e-12 43.4 In-house 21-111 (152) alignment
Range on Protein: 1015-1258
Range on HMM: 21-111/152.0
SPHVDREQILQQYFQKIVMLTNFTEANRQKCAVYFpielneifavaakcevfqlsaaardyfdryltptfvpdtvvassdaidyeisgrhigvesvkvtl
.   . ... ..  . |||||...| .. ||. |.                                                                 
tladfwrmlkelgittivmltellelgklkceqyi.................................................................

egdllealpaqgsffliknvgivrrngysvrklvllycirvpqsasyhlqkiycyHYWYPDWPDHHSPRDINTLLDTCLHVLNLGKCESEfdiyddtrse
                                                       .| .  ||||. | ..  ||. .| .  | . ...          
.......................................................qylhlpwpDhgvpdlsqlllflllfieklaldkgg..........

rnahlaaqrleiyqqdifnavqpLPVIHCSAGIGRTGCFTAILN
                         ..|||||.||||.. |.. 
.......................pvlVHCsaGvgRtgtlvaayl

0051429 (Phosphotyrosine protein) phosphatases II 1017-1373 1.7e-18 62.7 In-house 35-230 (272) alignment
Range on Protein: 1017-1373
Range on HMM: 35-230/272.0
HVDREQILQQYFQKIVMLTNFTEANRQKCAVYFPielneifavaakcevfqlsaaardyfdryltptfvpdtvvassdaidyeisgrhiGVESVKVTLEG
. | ... ..    ||.|.. .| .|.||  | |                                                       |.. . . ...
aadfwrlkelgiktivdLrseeErgrlkcdrywp.......................................................girylhlpild

DLLEALPaqGSFFLIKNVGIVRRNGYSVRKLVLLYCIRVPQSasyhlqkIYCYHYWYPDWPDHHSPRD-INTLLDTClhvlnlgkcesefdiyddtrser
|  .       .. .... ..  . | .|.|.| ...   ..          .|..| |||||. |.. . .||. .                       
dsaptil..ygalrvtllseellldyilrellltlllsagea.......revmhlhytdwpdhgvpqeallellell.......................

nahlaaqrleiyqQDifnavQPLPVIHCSAGIGRTGCFTAILNAVRQlrqslaysltgmltksltsssteeyhnptdsdssftcntirhishildhrdae
             .|     .   ..|||||..|||.. |.|  ...                                                     
.............ld.....ggpvlvHCsaGkdRTGtvvallllllg.....................................................

avktppsfdrlpkmpdifVD--------------VLGIVCNLRLQRGGMVQNSEQYELIHRAICLYLKRTLA
                  |.              ....|  || || |.||. |||. ...|.  .|.. |.
..................vsletivddYlltnlyleeaveelraqrpgavqteeqylflyeallellrslls

subfamily_Cele-PTP-9_pd Subfamily Cele-PTP-9 1021-1056 4.5e-06 20.9 In-house 46-81 (255) alignment
Range on Protein: 1021-1056
Range on HMM: 46-81/255.0
EQILQQYFQKIVMLTNFTEANRQKCAVYFPIELNEI
..| |.  ...|||..|.|....||  |||.|..| 
qtivqtktevvvmlcdfaeegvekcssyfplekdek

subfamily_hpo-7_pd Subfamily hpo-7 1022-1056 4.9e-06 20.6 In-house 53-87 (263) alignment
Range on Protein: 1022-1056
Range on HMM: 53-87/263.0
QILQQYFQKIVMLTNFTEANRQKCAVYFPIELNEI
 | |.  ...|||..|.|....||  |||.|..| 
tivqtktevvvmLcDfneegvekcssyfPlekdek

DSPc_SM00195 1023-1368 5.2e-26 86.9 In-house 89-262 (263) alignment
Range on Protein: 1023-1368
Range on HMM: 89-262/263.0
ILQQYFQKIVMLTNFTEANRQKCAVYFPIELneifavaakcevfqlsaaardyfdryltptfvpdtvvasS------------------Daidyeisgrh
....  . |||||.. | ...||. |.| |                                                           .          
vweekvkiivmlteeeengkekcdrywpees.......................................ggketfgkisvklvevekkk..........

igvesvkvtlegdllealpaqgsffliknvgivrrNGYSVRKLVLLYCIRvpqsasyhLQKIYCYHYWYPDWPDHHSPRDINTLLDTCLHVLNLGKCEse
                                   . . .|.| | .. .         ..  ...|.| .||||  | . . .|.    | .  . .  
...................................deiilrtleltkegk........eetrkvtqyqyknWpdhgvpdstksvlellravkksksts..

fdiyddtrsernahlaaqrleiyqqdifnavQPLPVIHCSAGIGRTGCFTAILNAVRQLRQSLAysltgmltksltsssteeyhnptdsdssftcntirh
                               ..  |.|||||.||||.| .|  ....|..                                       
...............................sgpivVhCsaGvgRtgtfvtidiilskleeekk....................................

ishildhrdaeavktppsfdrlpkmpdifVDVLGIVCNLRLQRGGMVQNSEQYELIHRAICLYL
                             ||.  ||..|| || ||||..|||  |..||  |.
.............................vdifeivkelRkqRpgmvqtleqYlfiyeaileyi

PTPc_SM00194 1023-1368 5.2e-26 86.9 In-house 89-262 (263) alignment
Range on Protein: 1023-1368
Range on HMM: 89-262/263.0
ILQQYFQKIVMLTNFTEANRQKCAVYFPIELneifavaakcevfqlsaaardyfdryltptfvpdtvvasS------------------Daidyeisgrh
....  . |||||.. | ...||. |.| |                                                           .          
vweekvkiivmlteeeengkekcdrywpees.......................................ggketfgkisvklvevekkk..........

igvesvkvtlegdllealpaqgsffliknvgivrrNGYSVRKLVLLYCIRvpqsasyhLQKIYCYHYWYPDWPDHHSPRDINTLLDTCLHVLNLGKCEse
                                   . . .|.| | .. .         ..  ...|.| .||||  | . . .|.    | .  . .  
...................................deiilrtleltkegk........eetrkvtqyqyknWpdhgvpdstksvlellravkksksts..

fdiyddtrsernahlaaqrleiyqqdifnavQPLPVIHCSAGIGRTGCFTAILNAVRQLRQSLAysltgmltksltsssteeyhnptdsdssftcntirh
                               ..  |.|||||.||||.| .|  ....|..                                       
...............................sgpivVhCsaGvgRtgtfvtidiilskleeekk....................................

ishildhrdaeavktppsfdrlpkmpdifVDVLGIVCNLRLQRGGMVQNSEQYELIHRAICLYL
                             ||.  ||..|| || ||||..|||  |..||  |.
.............................vdifeivkelRkqRpgmvqtleqYlfiyeaileyi

subfamily_Ptp69D_pd Subfamily Ptp69D 1023-1265 1.4e-10 35.8 In-house 111-248 (307) alignment
Range on Protein: 1023-1265
Range on HMM: 111-248/307.0
ILQQYFQKIVMLTNFTEANRQKCAVYFPIELNEIFAvAAKCEVFQlSAAARDYFDRYLTPTFVPDTVVASsdaidyeisgrhigvesvkvtlegdlleal
| .|  . ||||.| || ||.||| |.||| .  .      .. . .  . ||  | |  . . ...                                 
iaeqevtlivmlsnlteknrkkcakYWpiedevqyg.dilvklvs.eekhsdyiiReldvskkkeesgev..............................

paqgsffliknvgivrrngysvrklvllycirvpqsasYHLQKIYCYHYwyPDWPDHHSPRDINTLLDTCLHVLNLGKCEsefdiyddtrsernahlaaq
                                       . .|.  |||    |.| . |.  ..||.   .| .| | .                    
......................................edsrkvvqyhy..tgWkDskvPevargllklieqvrelykln....................

rleiyqqdifnaVQPLpVIHCSAGIGRTGCFTAILNAVRQLRQ
              |. |.||||| ||.| | |.   . ||..
............rsPi.vvhCsaGvgrsgifvaldsllqqlka

subfamily_PTPN6_pd Subfamily PTPN6 1023-1192 1.6e-07 25.7 In-house 118-212 (306) alignment
Range on Protein: 1023-1192
Range on HMM: 118-212/306.0
ILQQYFQKIVMLTNFTEANRQKCAVYFPIELNEIFavAAKCEVFQLSAAardyfdryltptfvpdtvvassdaidyeisgrhigvesvkvtlegdlleal
..|.  . |||.|. .| ...||| |.| | ..      | .| ..|                                                     
vwqensrvivmttkevErgkekCarYWPdeeekee..yGkisvtnvsek...................................................

paqgsffliknvgivRRNGYSVRKLVLLYCirvpqSASYHLQKIycYHYWYPDWPDHHSPRDINTLLDTC
               . . | .|.|..        . . . ...  ..| . .||||  |.| ...||  
...............sladYilRelsvskk.....kkkkeerev..fqyhfksWPdhgvpkdpgavLdfl

subfamily_PTPRB_pd Subfamily PTPRB 1023-1194 3.4e-06 21.3 In-house 114-207 (293) alignment
Range on Protein: 1023-1194
Range on HMM: 114-207/293.0
ILQQYFQKIVMLTNFTEANRQKCAVYFPIElneifavaakcevfqlsaaardyfdryltptfvpdtvvassdaidyeisgrhigvesvkvtlegdlleAL
....  . |||||.  |  ..||  |.| .                                                                      
vwekkssiivmltqlvekgkvkCeeYWPad....................................................................ee

P-AQGSfFLIKNVGIVRRNGYSVRKLVLLYcirvpqsasyHLQKIYCYHYWYPDWPDHHSPRDINTLLDTCLH
| . |.   .. |   . . . .|.| .            . ..    .| .  ||||  | . .|||| . .
pvlyGd.ikvtlvaeeeledwvirelkiek..........ekeerkvrqyhftsWpdhgvPektktlldfvrt

subfamily_PTPRD_pd Subfamily PTPRD 1024-1266 5.6e-15 50.0 In-house 112-244 (564) alignment
Range on Protein: 1024-1266
Range on HMM: 112-244/564.0
LQQYFQKIVMLTNFTEANRQKCAVYFPIElNeiFavaAKCEVFQLSAAARDYFDRYLTPTFVPDTVVassdaidyeisgrhigvesvkvtlegdllealp
 .|  . |||||.  | ...||. |.| . .      .... .. .  .   .  |   ||   .                                   
weqnsstiVmltkleEkgkvkchkYWPek.g..t...etygeltVtleeeeeladyeirtfklkkkk.................................

aqgsffliknvgivrrngysvrklvllycirvpqsasyHLQKIYCYHYWYPDWPDHHSPRDINTLLDTCLHVLNLGKcesefdiyddtrsernahlaaqr
                                      . ..    .. . .||||  |   ..|||   .| .| .                       
......................................ssesreVrqFhFtsWPdhgvpesatslLdlirkvralne.......................

leiyqqdifNAVQPLpVIHCSAGIGRTGCFTAILNAVRQLRQS
         .  .|. |.|||||.||||.| .|   .......
.........pdagPi.vVhCSaGVGRTGtfividamlerikee

0047943 (Phosphotyrosine protein) phosphatases II 1128-1368 2e-25 85.2 In-house 136-272 (273) alignment
Range on Protein: 1128-1368
Range on HMM: 136-272/273.0
FFLIKNVGIVRRNGYSVRKLVLLYCIrvpqsasyHLQKIYCYHYWYPDWPDHHSPRDINTLLDTCLHVLNLGKcesefdiyddtrsernahlaaqrleiy
 | ......  ...| ||.| | ..           .. ...|..|..||||. | ... ||. . .| .  .                           
kftvtllseetkddytvrtleltnlg........tgesrtvthfhytgwpdhgvppslesllefielvrkale...........................

qqdiF---NavqPLPVIHCSAGIGRTGCFTAILNAVRQLRQslaysltgmltksltsssteeyhnptdsdssftcntirhishildhrdaeavktppsfd
        |   .  |.|||||.||||.| |.. ...||.                                                            
....alpsn...gpvvVHCsaGvgRtgtfialdllldqlek...........................................................

rlpkmpDIFVDVLGIVCNLRLQRGGMVQNSEQYELIHRAICLYL
         |||| .|. || || ||||. |||.....|.. ||
......eggvdvleavkllrsqRpgmvqtpeqyrflyealleyl

0050432 (Phosphotyrosine protein) phosphatases II 1129-1371 1.5e-27 92.2 In-house 168-302 (308) alignment
Range on Protein: 1129-1371
Range on HMM: 168-302/308.0
FLIKNVGIVRRNGYSVRKLVLLYCIrvpqsasyHLQKIYCYHYWYPDWPDHHSPRDINTLLDTCLHVLNLGkcESefdiyddtrsernahlaaqrleiyq
| .... .  ...| ||.| | ..           . ....|..|..||||. | ... ||| . .| .    ..                         
ftvtllseevlddytvrtleltnlg........dgesrtvthfhytnWpdhgvPpspeilldflelvrksl..pg.........................

qdifnavqPLPVIHCSAGIGRTGCFTAILNAVRQLRQslaysltgmltksltsssteeyhnptdsdssftcntirhishildhrdaeavktppsfdrlpk
        .  |.|||||.||||.| |.. ...||..                                                               
........gpivVHCsaGvGRtGtfialdllleqlek...............................................................

mpDIFVDVLGIVCNLRLQRGGMVQNSEQYELIHRAICLYLKRT
  .  |||...|. || || ||||. |||....||.. |||. 
..eggvdvfeavkklReqRpgmvqtpeqylflyralleylklk

0051299 (Phosphotyrosine protein) phosphatases II 1129-1369 1.4e-26 89.0 In-house 149-287 (288) alignment
Range on Protein: 1129-1369
Range on HMM: 149-287/288.0
FLIKNVGIVRRNGYSVRKLVLLYC--IRvpqsasYHLQKIYCYHYWYPDWPDHHSPRDINTLLDTCLHVLnlgkcesefdiyddtrsernahlaaqrlei
. .... ..  ..| ||.| . ..  ..      .. ......|..|..||||. | ... ||| . .|                               
itvtllseevlddytvrtlevtnldlld......gdgesrtvthfhytnwpdhgvpdspellldflrlvr..............................

yqqD--IfnAVQPLPVIHCSAGIGRTGCFTAILNAVRQLRqslaysltgmltksltsssteeyhnptdsdssftcntirhishildhrdaeavktppsfd
   .     . ..  |.|||||.||||.| |.. ...||.                                                            
...kala..sgggpvvVHCsaGvgRtgtfialdllleqle............................................................

rlpkmPDIFVDVLGIVCNLRLQRGGMVQNSEQYELIHRAICLYLK
         ||||..|. || || ||||. |||.....|.. |||
.....keggvdvleavkrlreqRpgmvqtpeqyrfvyealleylk

0046845 (Phosphotyrosine protein) phosphatases II 1129-1372 7.7e-26 86.5 In-house 135-278 (284) alignment
Range on Protein: 1129-1372
Range on HMM: 135-278/284.0
FLIKNVGIVRRNGYSVRKLVLLYCirvpqsaSYHLQKIYCYHYWYPDWPDHHSPRDINTLLDTCLHVLNLGKC---Esefdiyddtrsernahlaaqrle
| .... .  ...| ||.| | ..       .|  . ....|..|..||||. | ... ||. .  | .| .    .                       
ftvtllseevkddytvrtleltnl.......gytgesrtvthfhytswpdhgvppspedlleflrlvrellenlpgg.......................

iyqqdifnavqPLPVIHCSAGIGRTGCFTAILNAVRQLRQSlaysltgmltksltsssteeyhnptdsdssftcntirhishildhrdaeavktppsfdr
           .  |.|||||.||||.| |.  . .||..                                                            
...........gpivVHCsaGvgRtGtfialdllleqleke...........................................................

lpkmpD--IFVDVLGIVCNLRLQRGGMVQNSEQYELIHRAICLYLKRTL
     .  . ||||..|. || || ||||. |||.....|.. |||..|
.....glllgvdvleavkrlreqRpgmvqtleqyrfvyealleylklkl

0039614 (Phosphotyrosine protein) phosphatases II 1129-1371 1.5e-24 82.4 In-house 156-292 (297) alignment
Range on Protein: 1129-1371
Range on HMM: 156-292/297.0
FLIKNVGIVRRNGYSVRKLVLLYcirvpQSASyhlqkIYCYHYWYPDWPDHHSPRDINTLLDTCLHVLNLGKCesefdiyddtrsernahlaaqrleiyq
| ......  ..|| ||.| . .      . |      ...|..|..||||. | ....||. .  | .  .                            
ftvtllkvehldgytvrtlevtn.....nges.....rtvthfqytgwpdhgvppslellleflelvrealae...........................

qdifNAVQPLPVIHCSAGIGRTGCFTAILNAVRQLRqslaysltgmltksltsssteeyhnptdsdssftcntirhishildhrdaeavktppsfdrlpk
    .  .   ..|||||.||||.| |.. ...||.                                                                
....lpkggpvlVHCsaGvgRtGtfiaaylmleqle................................................................

mPDIFVDVLGIVCNLRLQRGGMVQNSEQYELIHRAICLYLKRT
     |||| .|. || ||.|.||. .||. ...|.. .|||.
.keggvdvleavkelreqRpgavqtpsqyrflydallellkrk

0036941 (Phosphotyrosine protein) phosphatases II 1129-1371 1.7e-24 82.1 In-house 137-280 (297) alignment
Range on Protein: 1129-1371
Range on HMM: 137-280/297.0
FLIKNVGIVR--RNGYSVRKLVLLYCirvpqS-AsyhlQKIYCYHYWYPDWPDHHSPRDINTLLDTCLHVLNLGKCEsefdiyddtrsernahlaaqrle
| ......     ..| .|.| ...             .. ...|..|..||||. | ....||| .  |..  |                         
ftvtllsvevvllddytlrtlevtdt.....gng....esrtvthfhytgwpdhgvpespaslldfielvrkvlkll.......................

iyqqdifnAVQPLPVIHCSAGIGRTGCFTAILNAVRQLR---QSLAYSltgmltksltsssteeyhnptdsdssftcntirhishildhrdaeavktpps
          ..  ..|||||.||.|.| |.  ...||.       ..                                                    
........psggpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvd....................................................

fdrlpkmpdifvdVLGIVCNLRLQRGGMVQNSEQYELIHRAICLYLKRT
             .| .|. || || |.||. |||. ...|.  .||..
.............ileavkklReqRpgavqtleqyrflyeallellkkk

0043336 (Phosphotyrosine protein) phosphatases II 1129-1368 8e-24 80.0 In-house 144-277 (278) alignment
Range on Protein: 1129-1368
Range on HMM: 144-277/278.0
FLIKNVGIVRRNGYSVRKLVLLYcirvpqsaSYHLQKIYCYHYWYPDWPDHHSPRDINTLLDTCLHVLNLGkcesefdiyddtrsernahlaaqrleiyq
| ......   ..| ||.| . .         .. .. ...||.|..||||. | ....||| .  |..                               
ftvtllkeehlddytvrtlevtn........lgdgesrtvthyhylgwpdhgvpeslsllldflkavreal.............................

qdifNAVQPLPVIHCSAGIGRTGCFTAILNAVRQLRQslaysltgmltksltsssteeyhnptdsdssftcntirhishildhrdaeavktppsfdrlpk
    .  .   ..|||||.||||.| |.. ...||.                                                                
....edsngpvlVHCsaGvgRTGtfialyllleqlek...............................................................

mpDIFVDVLGIVCNLRLQRGGMVQNSEQYELIHRAICLYL
    .||.. .|. || ||.|.||. .||. ...|.. ||
..eggvdleeavkelreqRpgavqtpsqyrflyealleyl

0045450 (Phosphotyrosine protein) phosphatases II 1129-1369 9.9e-24 80.0 In-house 165-305 (307) alignment
Range on Protein: 1129-1369
Range on HMM: 165-305/307.0
FLIKNVGIVRRNGYSVRKLVLLYCirvpqsaSYHLQKIYCYHYWYPDWPDHHSPRDINTLLDTCLHVLNLGKCesefdiyddtrsernahlaaqrleiyq
| ......   .|| ||.| . ..       ..  . ....|..|..||||. | ....||| .  |..  .                            
ftvtllseehldgytvrtlevtdl.......dgtgesrtvthfhytgwpdhgvppsfeelldfieevrkalee...........................

qdifNAVQPLPVIHCSAGIGRTGCFTAILNAVRQLRQSlaysltgmltksltsssteeyhnptdsdssftcntirhishildhrdaeavktppsfdrlpk
    .  .   ..|||||.||||.| |.. . |||..                                                               
....lpkggpvlVHCsaGvgRtGtfiaaylmlrqleke..............................................................

mpdIF---VDVLGIVCNLRLQRGGMVQNSEQYELIHRAICLYLK
        ||.| .|. || ||.|.||| |||. ...|.. .|.
...gtlldvdlleavkllreqRpgavqnpeqyrflyeallelll

0042113 (Phosphotyrosine protein) phosphatases II 1129-1369 1.1e-22 76.1 In-house 109-244 (245) alignment
Range on Protein: 1129-1369
Range on HMM: 109-244/245.0
FLIKNVGIVRRNGYSVRKLVLLYCirvpqsasYHLQKIYCYHYWYPDWPDHHSPRDINTLLDTCLHVLnlgkcesefdiyddtrsernahlaaqrleiyq
| ......   ..| ||.| . .         .. ..  ..||.| .||||. | ....||| .  |.                                
ftvtllseehlddytvrtlevtnl........gddesrevihyhylpwpdhgvpdllellldflefvr................................

Q---DifnAVQPLPVIHCSAGIGRTGCFTAILNAVRQLRQslaysltgmltksltsssteeyhnptdsdssftcntirhishildhrdaeavktppsfdr
.   .     .   ..|||||.||||.| |.. ...||.                                                             
kalae...dsngpvlVHCsaGvgRtGtfiaaylmleqlek............................................................

lpkmpDIFVDVLGIVCNLRLQRGGMVQNSEQYELIHRAICLYLK
        |..  .|  || ||.|.||. .||. ...|.. .||
.....elgvsleeavkelrsqRpgavqtpsqyrflyeallellk

0040439 (Phosphotyrosine protein) phosphatases II 1129-1370 3.4e-22 74.7 In-house 111-248 (249) alignment
Range on Protein: 1129-1370
Range on HMM: 111-248/249.0
FLIKNVGIVRRNGYSVRKLVLLYCirvpqsasYHLQKIYCYHYWYPDWPDHHSPRDINTLLDTCLHVLnlgkcesefdiyddtrsernahlaaqrleiyq
| .... .   ..| ||.| | .         |. ......|..|.|||||. | ....||| .  |.                                
ftvtllsvevkddytvrtleltnl........ydgesrtvlhiqytdwpdhgvppsfedlldfieavr................................

qD----IfnAVQPLPVIHCSAGIGRTGCFTAILNAVRQLRQslaysltgmltksltsssteeyhnptdsdssftcntirhishildhrdaeavktppsfd
 .    .    .   ..|||||.||||.| |.. ...||.                                                            
.kaleel..pkggpvlVHCsaGvgRtGtfiaaylmleqlek...........................................................

rlpkmpDIFVDVLGIVCNLRLQRGGMVQNSEQYELIHRAICLYLKR
         ||.. .|. || ||.|.||| |||. ...|.. .|..
......elgvdleeavkllrsqRpgavqnpeqyrflyeallelllk

0045098 (Phosphotyrosine protein) phosphatases II 1129-1370 1.5e-17 59.3 In-house 121-274 (278) alignment
Range on Protein: 1129-1370
Range on HMM: 121-274/278.0
FLIKNVGIVRRNGYSVRKLVLLYCIRVPqsasYHLQKIYCYHYWYPDWPDHHSPRDI--NTLLDTCLHVLNLGKCESE-----Fdiyddtrsernahlaa
| .... . . . | .|.| . ..   .    ..|.. . .|..|. ||||..| .   . .|. .  ...  |   .     .                
ftvtllseevlddytlrtllvtnltver....edlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllssl................

qrleiyqqdIFNAVQPLPVIHCSAGIGRTGCFTAILNAVRqlrqslaysltgmltksltsssteeyhnptdsdssftcntirhishildhrdaeavktpp
         ...  .   ..|||||.||||.. |.    .                                                            
.........llldsggpvlVHCsaGvgRtGtlvaaylmle............................................................

sfdrlpkmpdI---FVDVLGIVCNLRLQRGG-MVQNSEQYELIHRAICLYLKR
               ||.| .|. || ||.| .||| |||. ........|.|
..........lleggvdlleavkelrsqRpglavqnleqyrflyefllelllr

Y_phosphatase Protein-tyrosine phosphatase 1159-1266 4.6e-12 41.2 Pfam-A 127-200 (235) alignment
Range on Protein: 1159-1266
Range on HMM: 127-200/235.0
ASYHLQKIYcYHYWYPDWPDHHSPRDINTLLDTCLHVLNLGkcesefdiyddtrsernahlaaqrleiyqqdifNAVQPLPVIHCSAGIGRTGCFTAILN
.. . ...  ....| .||||  |.. . |||..  | .                                   .| .   |.|||||.||||.| |.  
keesekrev.kqlhytnWpdhgvpespkslldlirkveksk.................................eaksgpvvVhCsaGvgRtgtfvaldi

AVRQLRQS
...||.. 
lleqleae

Y_phosphatase Protein-tyrosine phosphatase 1159-1266 4.6e-12 41.2 In-house 127-200 (235) alignment
Range on Protein: 1159-1266
Range on HMM: 127-200/235.0
ASYHLQKIYcYHYWYPDWPDHHSPRDINTLLDTCLHVLNLGkcesefdiyddtrsernahlaaqrleiyqqdifNAVQPLPVIHCSAGIGRTGCFTAILN
.. . ...  ....| .||||  |.. . |||..  | .                                   .| .   |.|||||.||||.| |.  
keesekrev.kqlhytnWpdhgvpespkslldlirkveksk.................................eaksgpvvVhCsaGvgRtgtfvaldi

AVRQLRQS
...||.. 
lleqleae

0048179 (Phosphotyrosine protein) phosphatases II 1162-1257 1.9e-08 29.7 In-house 43-104 (144) alignment
Range on Protein: 1162-1257
Range on HMM: 43-104/144.0
HLQKIYCYHYWYPDWPDHHSPRDINTLLDTCLHVLNLgkcesefdiyddtrsernahlaaqrleiyqqdifNAVQPLPVIHCSAGIGRTGCFTAIL
.  . . ..|.. .||||. | ... ||...  . ..                                   .     ..|||||.||||.. |. 
efleregiqylhlpwpDhgvpdllellleflefieea..................................leeggpvlVHCsaGvgRtgtlvaay

0048076 (Phosphotyrosine protein) phosphatases II 1165-1258 1.5e-09 33.2 In-house 44-103 (145) alignment
Range on Protein: 1165-1258
Range on HMM: 44-103/145.0
KIYCYHYWYPDWPDHHSPRDINTLLDTCLHVlnlgkcesefdiyddtrserN----AhlaaqrleiyqqdifnavQPLPVIHCSAGIGRTGCFTAILN
. . ..|.| .||||. | ....||. .  .                    .    .                      ..|||||.||||.. |.  
erlgiqylylpwpDhgvpdllellleflefi....................eealke..................ggpvlVHCsaGvgRtgtlvaayl

PTPc_DSPc_SM00012 1168-1364 1.1e-21 72.4 In-house 2-103 (105) alignment
Range on Protein: 1168-1364
Range on HMM: 2-103/105.0
CYHYWYPDWPDHHSPRDINTLLDTCLHVLNLGKCESEfdiyddtrsernahlaaqrleiyqqdifnavQPLPVIHCSAGIGRTGCFTAILNAVRQLRQSL
..||.|..||||. |.. . .|... .| .  . ...                               ..  |.|||||.||||.|.|.  ...||... 
vkhyhytgwpdhgvPeesdsilellravkknknkses...............................skpvvVhCsaGvgRtgtfvaldillqqleket

aysltgmltksltsssteeyhnptdsdssftcntirhishildhrdaeavktppsfdrlpkmpdIFVDVLGIVCNLRLQRGGMVQNSEQYELIHRAI
                                                                 .||.. ||. || || ||||. |||  ..||.
................................................................kevdifqivkelrkqRpgmvqteeqylflyral

subfamily_PTPN3_pd Subfamily PTPN3 1168-1262 1.1e-08 29.4 In-house 173-234 (280) alignment
Range on Protein: 1168-1262
Range on HMM: 173-234/280.0
CYHYWYPDWPDHHSPRDINTLLDTCLHVLNLGkcesefdiyddtrsernahlaaqrleiyqqdifnAVQPLP-VIHCSAGIGRTGCFTAILNAVRQ
  .  | .||||  | | . .|.   .| .|                                   ...  | |.|||||||||| . ..  |.  
ilqlqylaWpdhgvPddsadflefvervrklr..................................sgkeePvvvhCsaGigrtGvlilletalal

subfamily_PTPN9_pd Subfamily PTPN9 1169-1266 8.5e-08 26.6 In-house 176-253 (297) alignment
Range on Protein: 1169-1266
Range on HMM: 176-253/297.0
YHYWYPDWPDHHSPRDINTLLDtclhVLnlgkcesefdiyDDTRSERnahlAAQRLEIYQQDIFNAVQPLPVIHCSAGIGRTGCFTAILNAVRQLRQS
 |. .  |||.  |.. ..|||    ||            .  |...    |.   |. ... ... .|  |.|||||||||| |...  .. .|.. 
thfqflsWPdyGvPssaaslld....vl............ekvrekq....alavkelgdewkghpsgPPivvhcsaGiGrtGtfitldiclsrleev

subfamily_PTPN23_pd Subfamily PTPN23 1173-1372 1.2e-09 32.5 In-house 178-284 (288) alignment
Range on Protein: 1173-1372
Range on HMM: 178-284/288.0
YPDWPDHHSPRDINTLLDTCLHVLN-LGKCESEFDIyddtrsernahlaaqrleiyqqdifnavqPLpVIHCSAGIGRTGCFTAILNAVRQLRQSLAYSl
.  ||..  |   .|||.    | . . . . . ..                             || |.|||||.|||| |. .  |||.|..      
ltsWpelGvPasPetllqfldevesayeavqrkskt.............................Pl.vvhCsaGvgRtgvfalvyaavrelekgngll.

tgmltksltsssteeyhnptdsdssftcntirhishildhrdaeavktppsfdrlpkmpdifvDVLGIVCNLRLQRGGMVQNSEQYELIHRAICLYLKRT
                                                               |.. .|  || ||  |||..||..    |.  . .|.
...............................................................diiqvvsrlreqRrfmvqekeqlkfsyeavleaarrv

L
|
l

subfamily_Choan-PTP-1_pd Subfamily Choan-PTP-1 1222-1266 7.1e-08 26.9 In-house 195-238 (281) alignment
Range on Protein: 1222-1266
Range on HMM: 195-238/281.0
QRLEIYQQDIFNAVQPLpVIHCSAGIGRTGCFTAILNAVRQLRQS
 | |... .  .  .|| |||||||.||||.. |.  .|... ..
frkevlkltekktkapl.vihCsaGvGrtGtyialDrlvkaveae

subfamily_Choan-PTP-2_pd Subfamily Choan-PTP-2 1237-1266 3.2e-06 21.3 In-house 199-227 (270) alignment
Range on Protein: 1237-1266
Range on HMM: 199-227/270.0
PLpVIHCSAGIGRTGCFTAILNAVRQLRQS
|| ..|||||.||||.. |.  ||| | ..
Pl.lvHcsaGvgRtGtlialDiavrlLeet

subfamily_Cele-PTP-20_pd Subfamily Cele-PTP-20 1237-1274 3.5e-06 20.9 In-house 218-254 (290) alignment
Range on Protein: 1237-1274
Range on HMM: 218-254/290.0
PLpVIHCSAGIGRTGCFTAILNAVRQLRQSLAYSLTGM
|. |.|||||||||| |.||  ... | .  .. | ..
pv.vvhcsaGiGrtGtfvaievglqilldGkeldlldl

subfamily_PTPRB_pd Subfamily PTPRB 1239-1268 3.1e-06 21.4 In-house 221-250 (293) alignment
Range on Protein: 1239-1268
Range on HMM: 221-250/293.0
PVIHCSAGIGRTGCFTAILNAVRQLRQSLA
 |.|||||.|||| | |. . .......  
ivvhCsaGvGRtGtfialdrllqaieeedy

subfamily_PTPRB_pd Subfamily PTPRB 1333-1370 1.3e-07 26.0 In-house 250-287 (293) alignment
Range on Protein: 1333-1370
Range on HMM: 250-287/293.0
FVDVLGIVCNLRLQRGGMVQNSEQYELIHRAICLYLKR
.||..|||..|| .|  .||. .||  ||...  .|..
yvdifgivaelReeRnllvqtekqYifihqcvldllrk

subfamily_PTPRD_pd Subfamily PTPRD 1333-1369 1.3e-07 25.7 In-house 246-282 (564) alignment
Range on Protein: 1333-1369
Range on HMM: 246-282/564.0
FVDVLGIVCNLRLQRGGMVQNSEQYELIHRAICLYLK
 ||. ..| .|| ||  |||. |||  ||.||  .|.
tvDiyqyvkalrkqRnamVqteeQYiFiheaileala

subfamily_Anemone-PTP-5_pd Subfamily Anemone-PTP-5 1333-1369 1.9e-07 25.5 In-house 248-284 (319) alignment
Range on Protein: 1333-1369
Range on HMM: 248-284/319.0
FVDVLGIVCNLRLQRGGMVQNSEQYELIHRAICLYLK
 .||  .| .||.||  |||. |||..|. |.  ...
vlDvfstvsrlRtqRnimvqrpeqYkfiyealleave

subfamily_Urchin-PTPRB-like_pd Subfamily Urchin-PTPRB-like 1333-1365 7.2e-07 23.5 In-house 244-276 (288) alignment
Range on Protein: 1333-1365
Range on HMM: 244-276/288.0
FVDVLGIVCNLRLQRGGMVQNSEQYELIHRAIC
..||.|.|..|| ||  .||. .||| |.... 
yiDvagtvaklRkqRallvqtlkqYefiyevll

subfamily_Anemone-PTP-6_pd Subfamily Anemone-PTP-6 1333-1369 7.8e-07 23.4 In-house 245-281 (318) alignment
Range on Protein: 1333-1369
Range on HMM: 245-281/318.0
FVDVLGIVCNLRLQRGGMVQNSEQYELIHRAICLYLK
 |||...| .|| ||  |||  .|||.|. ..  .|.
lvDvfqtvkqlreqrnlmvqtedqyefiydvlleala

subfamily_Sponge-PTP5_pd Subfamily Sponge-PTP5 1333-1364 6.5e-06 20.2 In-house 231-262 (283) alignment
Range on Protein: 1333-1364
Range on HMM: 231-262/283.0
FVDVLGIVCNLRLQRGGMVQNSEQYELIHRAI
 |||  .| ..| || ..||. .|| |.| ..
vvdvfavvkimreqrmmavqtldqyklvhelv

subfamily_PTPN12_pd Subfamily PTPN12 1334-1373 5.7e-08 27.0 In-house 243-282 (290) alignment
Range on Protein: 1334-1373
Range on HMM: 243-282/290.0
VDVLGIVCNLRLQRGGMVQNSEQYELIHRAICLYLKRTLA
.||  .| .|| ||  .||  |||||...|.  .....|.
ldvfdlvlelrkqraalvqtkeqyelvykavaelvqkele

Y_phosphatase Protein-tyrosine phosphatase 1334-1364 5.1e-07 24.7 Pfam-A 203-233 (235) alignment
Range on Protein: 1334-1364
Range on HMM: 203-233/235.0
VDVLGIVCNLRLQRGGMVQNSEQYELIHRAI
|||| ||..|| || ||||. |||. ...||
vdvlqivkelRkqRpgmvqsleqYiflykai

Y_phosphatase Protein-tyrosine phosphatase 1334-1364 5.1e-07 24.7 In-house 203-233 (235) alignment
Range on Protein: 1334-1364
Range on HMM: 203-233/235.0
VDVLGIVCNLRLQRGGMVQNSEQYELIHRAI
|||| ||..|| || ||||. |||. ...||
vdvlqivkelRkqRpgmvqsleqYiflykai

subfamily_Ptp69D_pd Subfamily Ptp69D 1334-1369 2.2e-06 22.0 In-house 252-287 (307) alignment
Range on Protein: 1334-1369
Range on HMM: 252-287/307.0
VDVLGIVCNLRLQRGGMVQNSEQYELIHRAICLYLK
||.  .|..|| ||  .||. |||. ..||.  | .
vdifetvkdLrsqRnllvqsleqYvflyralldyss

subfamily_Choan-PTP-2_pd Subfamily Choan-PTP-2 1334-1371 3.8e-06 21.1 In-house 230-267 (270) alignment
Range on Protein: 1334-1371
Range on HMM: 230-267/270.0
VDVLGIVCNLRLQRGGMVQNSEQYELIHRAICLYLKRT
|||| |. .|| .|  .|| .||||....|. .| .|.
vdvlaiieelRkdRmalvqhpeqyeflykavveyaerr