Gene PTP-ER in Drosophila melanogaster

Synonym: CG9856, Dmel\CG9856, ER2-5, ptp-er, Dmel_CG9856, PTP-ER

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family PTP
Subfamily PTPN5_RR
Protein sequence
ID Type Fasta BLAST phosphatome Note
DmelP044_AA protein Get Run
DmelP044_AA_887-1369 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_Anemone-PTP-2_pd Subfamily Anemone-PTP-2 873-1001 3.9e-12 41.0 In-house 14-124 (298) alignment 
Range on Protein: 873-1001
Range on HMM: 14-124/298.0
VSRMAQPIPELKENEQKRIFRDLHKEFWDLPLNHQEKPMVFGSQTKNRYKTILPNENSRVLLESESSEltsllgeikrtssvtasEDLPYINANYIKGPD
....|.  .. |    .  |. |..   ... ...|       . ||||  |.. . |||.||.|...                 |.  |||| .... .
lqklaavkkkkkltgyalefqrlnsvsseieeeekevarkpenkkkNRyadiialdssRvvLekedad.................eesdYiNAsflhayk

YVSkCYVATQGPLPNTIFEFWLMIYQNTQ
  .  ..|||.||..|. .|| |. ..  
grn.afiatqaPltetvedFWrmvteedi
subfamily_PTPRA_pd Subfamily PTPRA 880-1000 3e-10 34.5 In-house 16-125 (330) alignment 
Range on Protein: 880-1000
Range on HMM: 16-125/330.0
IPELKENEQKRIFRD---LHKEFWDLPLNHQEKPM----VFGSQTKNRYKTILPNENSRVLLesesseltsllgeikrtSSVTASEDLPYINANYIKGPD
. .|.|. ..|.  |   ...||  ||  . .  .        . |||.  |||.. ||| |                 | .   |.  |||| .|.|  
vekleeeirirsaddnklfreefnalPagpiqatlelaskeenkeknrvvnilPydfsrvil.................svkeGveesdyinasfidGyk

YvSKCYVATQGPLPNTIFEFWLMIYQNT
   . ..|.|||. .|. .|| ||..  
e.kdkfiaaqGPkeetvedfwrmiweqk
subfamily_PTPN1_pd Subfamily PTPN1 887-1003 1.9e-11 38.2 In-house 7-98 (290) alignment 
Range on Protein: 887-1003
Range on HMM: 7-98/290.0
EQKRIFRDLHKEFWDLPLNHQEKPMvfgSQTKNRYKTILPNENSRVLLESESSeltsllgeikrtssvtasedlPYINANYIKGPDyVSKCYVATQGPLP
  | |..|..||  |.| .. ..|     ...|||. . | . ||. ||...                       ||||. .. .. . . |. ||||||
lykeiyldirkeasdfptreaklpe...nrnlnryrdvspydhsrikleradn.....................dyinaslvelee.akrsyiltqGPlp

NTIFEFWLMIYQNTQRY
||.  ||.|....  . 
ntvdhfWqmvWeqkska
0040438 (Phosphotyrosine protein) phosphatases II 888-1371 6.1e-52 172.2 In-house 16-279 (317) alignment 
Range on Protein: 888-1371
Range on HMM: 16-279/317.0
QKRIFRDLHKEFWDLPLNHQEKPMVFGSQTKNRYKTILPNENSRVLLESesseltsllgeikrtssVTASEDLPYINANYIKGPDYVSKcYVATQGPLPN
....... .... .|.|.. .  .   .. ||||. |||...||| | .                 ..  .|. ||||.|..||..  | ..||||||||
dftalleefedllslkldtysvaelpenkdknrypdilpydhsRVkLsp.................lggdldsdYInAsyvdgpnlkrk.fIatqgPlpn

TIFEFWLMIYQNtqryirrcvdggssssphvdreqilqqYFQKIVMLTNFTEANRQKCAVYFPIelNEIFAVAakcevfqlsaaardyfdryltptfvpd
|.. || |....                             . |||||...| .|.||| |.|   .|   .                            
tvedFwrmvweq...........................gvtvivmLteleelgrekcaqYwpl..getltyg...........................

tvvassdaidyeisgrhigvesvkvtlegdllealpaqgsFFLIKNVGIVRRNGYSVRKLVLLYCirvpqsasYHLQKIYCYHYWYPDWPDHHSPRDINT
                                         | .......  .|. .|.| . .         .. .. ...|..|..||||. | ....
........................................dftvtllseeelagitlrtlevedl........gdsesrtvthfhytgWpdhgvppspdl

LLDTCLHVLNLGkcesefdiyddtrsernahlaaqrleiyqqdifNAVQPLPVIHCSAGIGRTGCFTAILNAVRQLRqslaysltgmltksltsssteey
||| .  | .                                   .  .   ..|||||.||||.| |.. ...||.                       
lldfleavreal.................................edpggpvlVHCsaGvgRtGtfiaaylmleqle.......................

hnptdsdssftcntirhishildhrdaeavktppsfdrlpkmPDIFVDVLGIVCNLRLQRGGMVQNSEQYELIHRAICLYLKRT
                                             .|||  .|. || ||.|.||. |||. ...|.. ||||.
..........................................keggvdveeavkelreqRpgavqtpeqyrflydalleylkrk
0036941 (Phosphotyrosine protein) phosphatases II 888-1056 6.4e-25 83.5 In-house 15-131 (297) alignment 
Range on Protein: 888-1056
Range on HMM: 15-131/297.0
QKRIFRDLHKEFWDLPLNHQEKPmvfGSQTKNRYKTILPNENSRVLLESESseltsllgeikrtssvtasedLPYINANYIKGPDYVSKcYVATQGPLPN
 .. |..| . ... .|.....|   . ..||||| |||....|| |..|.                       ||||.|..|.|.  | ..||||||||
llkefeellpllllgslsvallp...enleknRykdilpydhtRVklddeg.....................sdYinAsyvdgydlkrk.fIatqgPlpn

TIFEFWLMIYQNtqryirrcvdggssssphvdreqilqqYFQKIVMLTNFTEANRQKCAVYFPIELNEI
|. .|| |....                             . |||||...| .|.||| |.| | .| 
tvedFWrmvweq...........................nvtvIvmltelvelgrekcaqywpleeges
subfamily_PTPN5_RR_pd Subfamily PTPN5_RR 889-1374 1.1e-131 433.0 In-house 1-274 (274) alignment 
Range on Protein: 889-1374
Range on HMM: 1-274/274.0
KRIFRDLHKEFWDLPLNH-QEKPMVFGSQTKNRYKTILPNENSRVLLESESSEltsllgeikrtssvtaSEDLPYINANYIKGPDYVSKCYVATQGPLPN
||.|.||.|||..||||. ||...|||||||||||||||||||||||||||||                .||..|||||||||.|..||.||||||||||
krsfkdlekeflelPlnfdqeeldvfgsqtknryktilPnensrvllesesse................dedssyinanyikGydeeskayvatqGPlpn

TIFEFWLMIYqntqryirrcvdggssssphvdreqilQQYFQKIVMLTNFTEANRQKCAVYFPielneifavaakcevfqlsaaardyfdryltptfvpd
|...||.|||                           |...|.|||||...|||.||||||||                                     
tvadfWrmiy...........................qeevqvivmltklkeaneqkCavyfP.....................................

tvvassDAIDYEISGRHIGVEsvkvtlegdllealpaqgsfflIKNVGIVRRNGYSVRKLVLLYCIRvPQSasyhlqkiyCYHYWYPDWPDHHSPRDINT
      ||.|||||.|...||                      ||...||.||.||||||||.|..| ..|         ..||||.|||||.||.|.||
......daedyeiserygdve......................ikvekiverndysvrklvlkyler.ers.........vkhywytdWPdhksPddant

LLDTCLHVlnlgkcesefdiyDDTRSERNAHLAAQrleiyqqdifnavqplpVIHCSAGIGRTGCFTAILNAVRQLRQslaysltgmltksltsssteey
|||..|.|             ...|.|.||.||..                 |.||||||||||||.||..||||||.                      
lldlvlev.............eesreeenaklapv.................vvhCsaGiGrtGcfiaisiavrqlre......................

hnptdsdssftcntirhishildhrdaeavktppsfdrlpkmpDIFVDVLGIVCNLRLQRGGMVQNSEQYELIHRAICLYLKRTLAL
                                           .|.||||.|||||||.||||||.||||||||||.||||||.|||
...........................................eivvdvlkivcnlrldrGGmvqtseqyelihralclylkrllal
0043336 (Phosphotyrosine protein) phosphatases II 889-1055 3.9e-24 81.0 In-house 19-136 (278) alignment 
Range on Protein: 889-1055
Range on HMM: 19-136/278.0
KRIFRDLHKEFWDLPLNHQEKPMVFGSQTKNRYKTILPNENSRVLLESesseltsllgeikrtssVTASEDLPYINANYIKGPDYVSKcYVATQGPLPNT
|....  ..|... .|....  .   ...||||| |||...||| |..                 ..  .|. ||||.|..|...  | ..|||||||.|
ktllllefeellsfkldtysiallpenkdknrykdilpydhsrvklsl.................lggdldsdYinAsyvdgynvprk.fiatqgPlpet

IFEFWLMIYQNtqryirrcvdggssssphvdreqilqqYFQKIVMLTNFTEANRQKCAVYFPielnE
.  || |....                             . |||||...| .|.||| |.|    .
vedFwrmvwel...........................gvttivmLtelvelgrvkcaqYwp....g
subfamily_PTPRD_pd Subfamily PTPRD 892-1003 3.9e-16 53.8 In-house 29-118 (564) alignment 
Range on Protein: 892-1003
Range on HMM: 29-118/564.0
FRDLHKEfWDLPLNHQEKPMvfgSQTKNRYKTILPNENSRVLLesesseltsllgeikrtSSVTASEDLPYINANYIKGPDyVSKCYVATQGPLPNTIFE
.......    . .. .||.    . ||||. |.. ..||| |                 |.| . |.  ||||..|.| .  .| |.||||||..|| .
ykkieeg.qqftweaankpa...NkaKNRyanivaYdhsRVvL.................skvegdegsDYINAsfidgyr.krkayIAtqgPlaetied

FWLMIYQNTQRY
|| |....  . 
FWRmvweqnsst
0050432 (Phosphotyrosine protein) phosphatases II 893-1054 6e-27 90.2 In-house 42-159 (308) alignment 
Range on Protein: 893-1054
Range on HMM: 42-159/308.0
RDLHKEFWDL----PLNHQEKPMVFGSQTKNRYKTILPNENSRVLLesesseltsllgeikrtssvtaSEDLPYINANYIKGPD-YVSKCYVATQGPLPN
  |..||..|    ||.  .  .    ..||||| |||...||| |                      .|.  ||||.|..|.. .... ..||||||||
glleeefeellsvkplleysvallpenkdkNrykdilpydhsRVkl......................degsdYInAsyvdgyssklprkfIatqgPlpn

TIFEFWLMIYQntqryirrcvdggssssphvdreqilqQYFQKIVMLTNFTEANRQKCAVYFPIELN
|.  || |...                           |  . |||||...| .|.||| |.| ||.
tvedFwrmvwe...........................qnvrvIvmLtklvengrekcaqYwplelg
0045450 (Phosphotyrosine protein) phosphatases II 894-1056 8.5e-24 80.3 In-house 34-159 (307) alignment 
Range on Protein: 894-1056
Range on HMM: 34-159/307.0
DLHKEFWDLPLNHQEKPMVFGSQTKNRYKTILPNENSRVLLESESseltsllgeikrtssvTASEDLPYINANYI--------KGPDYvSKCYVATQGPL
  ...... .|.. .  .   ...||||| |||....|| | |..                  .||  ||||.|.        .|.|  .. ..||||||
ekllsvtvfllgeysiallpenkdknrykdilpydhtRVklssld................gsledsdYiNAsyvrvpllllldgydl.krkfIatqgPl

PNTIFEFWLMIYQntqryirrcvdggssssphvdreqilqQYFQKIVMLTNFTEANRQKCAVYFPIElNEI
|.|. .|| |...                           |  . |||||...| .|.||| |.| | .| 
petvedFwrmlwe...........................qgvtvivmltelvelgrekcaqywPde.gee
subfamily_Ptp69D_pd Subfamily Ptp69D 894-1000 1.1e-10 36.1 In-house 23-115 (307) alignment 
Range on Protein: 894-1000
Range on HMM: 23-115/307.0
DLHKEFWDLPLNHQEKPMVFGSQ----TKNRYKTILPNENSRVLLESesseltsllgeikrtssVTASEDLPYINANYIKGPDYvSKCYVATQGPLPNTI
 | ||.  |. .. .|  ... .     ||||. | . .. || |.                  .. .||  ||||..||| .  .| ..| |.|. .||
glakeyekLeareidkstkvsekkenalknRyedikafDktRvkLkk.................ingkedsdYinasfikgyke.kkkfiaaqdPveati

FEFWLMIYQNT
..|| || .  
gDfWRmiaeqe
0046845 (Phosphotyrosine protein) phosphatases II 895-1056 3.4e-26 87.7 In-house 2-129 (284) alignment 
Range on Protein: 895-1056
Range on HMM: 2-129/284.0
LHKEFWDLPLNHQ------EKPMVFGSQTKNRYKTILPNENSRVLLESESSE--LTSllgeikrtssvtasedlpYINANYIKGPD----YVSKCYVATQ
|..||. |. .        .  .    ..||||| |||...||| | |....   ..                  ||||.|..|.|    |..| ..|||
leeefeellsltvklllslsvallpenlsknRykdilpydhsRVklksldgdledsd..................YinAsyvdgydldltyikkkfIatq

GPLPNTIFEFWLMIYQNtqryirrcvdggssssphvdreqilqqYFQKIVMLTNFTEANRQKCAVYFPIElNEI
||||||. .|| |....                             . |||||...| .|.||| |.| | .| 
gPlpntvedFwrmvweq...........................nvrvIVmltelvengrekcaqYwple.gev
subfamily_Urchin-PTP-1_pd Subfamily Urchin-PTP-1 895-1001 4e-11 37.3 In-house 21-112 (315) alignment 
Range on Protein: 895-1001
Range on HMM: 21-112/315.0
LHKEFWDLP---LNHQEKPMVFGSQTKNRYKTILPNENSRVLLEsesseltsLlgeikrtssVTASEDLPYINANYIKGPDYvSKCYVATQGPLPNTIFE
. .|| |||     .|        ..||||| ||| ...|| ||        .         .  | |  |||| |||. |   |.|.|.||||. .. .
fseefhdlpdPdiyrqrvaretinfkknryknilPldsarvkle........v.........iddsPdsdyinasyiksvdd.dkayiasqgPlkasvdd

FWLMIYQNTQ
|| |..|.  
fwrmvlqekv
subfamily_Urchin-PTP-4_pd Subfamily Urchin-PTP-4 895-1006 1.4e-10 35.1 In-house 22-118 (392) alignment 
Range on Protein: 895-1006
Range on HMM: 22-118/392.0
LHKEFWDLP---LNHQEKPMVFGSQTKNRYKTILPNENSRVLLEsesseltsLlgeikrtssVTASEDLPYINANYIKGPDyVSKCYVATQGPLPNTIFE
. .|| |||   . .|        . ||||| ||| ...|| ||        .         .  . |  |.|| ||.. |   |.|.|.||| . .. .
ffeefhdlpgpdiypqtvaqkeinlkknryknilpydsarvkle........v.........iddipdsdylnasyipsfd.nekayiasqgpnaasldd

FWLMIYQNTQRYIRR
|| |..|.    |  
fwrmvfqenvttiam
subfamily_Urchin-PTP-5_pd Subfamily Urchin-PTP-5 898-1004 2.2e-10 35.2 In-house 31-120 (297) alignment 
Range on Protein: 898-1004
Range on HMM: 31-120/297.0
EFWDLPLNHQEKPMVFGSQ---TKNRYKTILPNENSRVLLESESSEltsllgeikrtssvtasEDLPYINANYIKGPDYvskCYVATQGPLPNTIFEFWL
|| .||     .  |   .    |.||| ||| . ||| |..  ..                  |  |.|| ..||  .    ...|| | ..|. .|| 
eflclpeaniqpqtvaekkvnfeksRYkniLPydssRvkLaivndd.................pdsDyvnasfvkgnkh...rlittqmPmkatvadfWa

MIYQNTQRYI
|....    |
mvldeqvsti
0051299 (Phosphotyrosine protein) phosphatases II 903-1054 1.5e-25 85.7 In-house 37-141 (288) alignment 
Range on Protein: 903-1054
Range on HMM: 37-141/288.0
PLNHQEKPMVFGSQTKNRYKTILPNENSRVLLEsesseltsllgeikrtsSVTASEDLPYINANYIKGPDYVSKcYVATQGPLPNTIFEFWLMIYQNtqr
| ...   .    ..||||. |||...||| |                  ..  .|.  ||||.||.|...  | ..|||||||||. .|| |....   
pdltlsaallpenleknRysdilpydhsRVkLs.................vldgvegsdYinAsyidgynlkrk.fIatqgPlpntvedFWrmvweq...

yirrcvdggssssphvdreqilqqYFQKIVMLTNFTEANRQKCAVYFPIelN
                          . |||||...| .|.||| |.|   .
........................nvrvIvmltklvelgrekcaqYwpl..g
subfamily_Choan-PTP-2_pd Subfamily Choan-PTP-2 907-1069 6.8e-26 85.8 In-house 12-131 (270) alignment 
Range on Protein: 907-1069
Range on HMM: 12-131/270.0
QEKPMVFGSQTKNRYKTILPNENSRVLLesesseltsllgeikrtSSVTASEDLPYINANYIKGPDYVSKCYVATQGPLPNTIFEFWLMIYQNTQryirr
.. | .   .. |||. |||. ..|| |                 ....  .   ||||||..| |  .| |.|..||||.|...|| ||...       
sdlpeaargkklnRyadiLPsPatRvrl.................eeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekv.....

cvdggssssphvdreqilqqyfQKIVMLTNFTEANRQKCAVYFPIELNEIFA-VAAKCEVFQLS
                      . |||.|...| .|.||..|.| | .|  .  . | .|..||
......................taivmttgleEkgrkkCerYWpaepkekvkledgkikvlals
0039614 (Phosphotyrosine protein) phosphatases II 907-1059 5.9e-25 83.8 In-house 48-152 (297) alignment 
Range on Protein: 907-1059
Range on HMM: 48-152/297.0
QEKPMVFGSQTKNRYKTILPNENSRVLLESESseltsllgeikrtssvTASEDLPYINANYIKGPDYVSKCYVATQGPLPNTIFEFWLMIYQNtqryirr
..  .   ...||||| |||...||| | .|                    .|. ||||.|..|.|.... ..|||||||.|.  || |....       
ysiallpenkdknrykdilpydhsrvklkped................gvdldsdYinAsyvdgydlltrkfIatqgPlpetvedFwrmvweq.......

cvdggssssphvdreqilqqYFQKIVMLTNFTEANRqKCAVYFPIELNeifaV
                     .. |||||...| .| ||| |.| | .    .
....................gvtvivmLtklvelgr.kcaqywpeegg....t
0047943 (Phosphotyrosine protein) phosphatases II 908-1076 2.2e-25 85.1 In-house 31-150 (273) alignment 
Range on Protein: 908-1076
Range on HMM: 31-150/273.0
EKPMVFGSQTKNRYKTILPNENSRVLLESESSEltsllgeikrtssvtasedlpYINANYIKGPDYVSKcYVATQGPLPNTIFEFWLMIYQntqryirrc
.  .    ..||||| |||...||| |....|                      ||||.|..|...  | ..|||||||||. .|| |...         
svallpenkdknrykdilpydhsrvklgdggsd.....................yinAsyvdgynlkrk.fiatqgPlpntvedfwrmvwe.........

vdggssssphvdreqilqQYFQKIVMLTNFTEANRQKCAVYFPIELNEIFAVAAKCEVFQLSAAARDYF
                  |  . |||||...| .|.||| |.| | .|.. .  |  |  ||   .|..
..................qnvrviVmLtelvelgrekcaqYwpleggelsltygkftvtllseetkddy
subfamily_Anemone-PTP-6_pd Subfamily Anemone-PTP-6 910-1002 6.3e-14 46.8 In-house 41-115 (318) alignment 
Range on Protein: 910-1002
Range on HMM: 41-115/318.0
PMVFGSQTKNRYKTILPNENSRVLLESESSELTSllgeikrtssvtaseDlpYINANYIKGPDyVSKCYVATQGPLPNTIFEFWLMIYQNTQR
 .    ..||||  ||. ...||.|.  ..| .|               |  ||||||| |    .| |.|.|.|||.|| .|| |...   .
slepvnkaknryanilaydhtrvkLqmlegeegs...............D..yinanyidGyr.rkkayiaaqaPlpetieDfWrmvWeqnsa
0045098 (Phosphotyrosine protein) phosphatases II 911-1004 7.1e-19 63.7 In-house 29-92 (278) alignment 
Range on Protein: 911-1004
Range on HMM: 29-92/278.0
MVFGSQTKNRYKTILPNENSRVLlesesseltsllgeikrtssvtasedlPYINANYIKGPdyvSKCYVATQGPLPNTIFEFWLMIYQNTQRYI
.  |.. ||||| |||...|||                             ||||.||.|.   .| ..|||||||.|.  || |....  ..|
lylgnldknRykdilpydhsrVk...........................dYINAsyidgy...pkkfIatqgPlpstvadfwrmlwelgitvi
0040439 (Phosphotyrosine protein) phosphatases II 912-1054 1.6e-19 65.9 In-house 8-103 (249) alignment 
Range on Protein: 912-1054
Range on HMM: 8-103/249.0
VFGSQTKNRYKTILPNENSRVLLESesseltsllgeikrtssVTASEDLPYINANYIKGPDYVSKcYVATQGPLPNTIFEFWLMIYQntqryirrcvdgg
   .. ||||. |||...||| |..                 .   ..  ||||.||.|...  . ..|||||||.|.  || |...             
lpenkdknrypdilpydhsrvklsi.................lpglflsdyinAsyidgyyikrr.fiatqgPlpetvedfwrmlwe.............

ssssphvdreqilqQYFQKIVMLTNFTEANRQKCAVYFPIelN
              .  . |||||...| .|.||| |.|   .
..............lgitvivmLtslvelgrekcaqywpl..g
subfamily_PTPN9_pd Subfamily PTPN9 912-1002 5.5e-11 37.0 In-house 39-111 (297) alignment 
Range on Protein: 912-1002
Range on HMM: 39-111/297.0
VFGSQTKNRYKTILPNENSRVLLESESSEltsllgeikrT-SsvtaseDlpYINANYIKGPDyVSKCYVATQGPLPNTIFEFWLMIYQNTQR
. .  .||||. .|  ...|| |.... .          . |      |  |||||.. |     |...||||||..|. .||.|....  .
lranleknrytdvlcydetrvvlakvded..........eas......d..yinanfvdGyk.qkkafiatqGplkktvsdfWrmvWeqevl
0037934 (Phosphotyrosine protein) phosphatases II 913-1368 7.9e-37 122.5 In-house 8-242 (243) alignment 
Range on Protein: 913-1368
Range on HMM: 8-242/243.0
FGSQTKNRYKTILPNENSRVLLesesseltsllgeikrtssvtasEDLPYINANYIKGPDyvskCYVATQGPLPNTIFE----FWLMIYQNtqryirrcv
  ...||||..|||...||| |                       |.  |||||.|....     . |||||||.|...    || |....         
penlsknrysdilpydhsrvkl.......................egsdyinanliyvtp....rliatqgPlpetveddlasfwrmlwel.........

dggssssphvdreqilqqYFQKIVMLTNFTEANRQKCAVYFPielNEIfaVAAKCEVFQLSAAardyfdryltptfvpdtvvassdaidyeisgrhigve
                   .. |||||...| .|.||| |.|   .|.  .  . .|  ||                                       
..................gitvivmltelvElgrekcaqywp...gev..tygdftvtllsee.....................................

svkvtlegdllealpaqgsffliknvgivRRNGYSVRKLVLLycirvpqSASYHLQKIYCYHYWYPDWPDHHSPRDINTLLdtclhvlnlgkcesefdiy
                               ..| ||.|.|          ..  .. . .||.|  ||||. | ... ||                   
.............................hlddytvrtllle.......nldlddltrlvihyhylpwpdhgvPdspedll...................

ddtrsernahlaaQ---------------RleiyqqdiFNAVQPLPVIHCSAGIGRTGCFTAILNAVRQLRQSlaysltgmltksltsssteeyhnptds
             .               .         .  .   ..|||||.||||.. |..   ..|. .                           
.............dfldevrefieellsll........aldsggpvlVHCsaGvgRtGtliaaylmllllgvd...........................

dssftcntirhishildhrdaeavktppsfdrlpkmpdifvdVLGIVCNLRLQRGG-MVQNSEQYELIHRAICLYL
                                          .. .|. || ||.| .||. .||. ...|.. .|
..........................................leeavkllreqRpgkavqtpsqyrflyeallell
0049772 (Phosphotyrosine protein) phosphatases II 913-1370 5.3e-23 77.7 In-house 44-282 (314) alignment 
Range on Protein: 913-1370
Range on HMM: 44-282/314.0
FGSQTKNRYKTILPNEnSRVLLESESSeltsllgeikrtssvtasEDLPYINANYIKGPdyvsKCYVATQGPLPNTIFEF----------WLMI--YQNT
|  ..||||. ||| . .|| | ...                   ..  ||||.|..|.    . ..||||||..|.. |          | |.  ... 
flnrdknryldilpad.nrvilpglpv..................sgsdyinasyvdgf....lkfIatqgpleitvvdfreepvlyyngwrmvlrgdln

QRYirrcvdggssssphvdreqilqqyfqkIVM---------------------LTNFTEANrqkcavyfpiE----------Lneifavaakcevfqls
 |.                           |||                     |..... .                                      
vrd...........................ivmsrdevladelsrLdaAlgKtpllildgng..........neptaadlellk................

aaardyfdryltptfvpdtvvassdaidyeisgrhigvesvK-------Vtlegdllealpaqgsffliknvgivrrngysvrklvllycirvpqsasyh
                                         .       .                                                  
.........................................eelydpelf..................................................

lqKIYCYHYWYPDWPDHHSPrDINTLLDTCLHVLNLgKcesefdiyddtrsernahlaaqrleiyqqdifnaVQPLPVIHCSAGIGRTGCFTAILNAVRQ
  . . ..|.. ..||.. | ... ... . ..... .                                   .   ..||.||.||||.| ..   ...
..erlgikylripvpDgsap.lledfdeflefieea.d..................................kggpvlvHCkaGkgRtgtfvvaaylmkl

LRqslaysltgmltksltsssteeyhnptdsdssftcntirhishildhrdaeavktppsfdrlpkmpdifVDVLGIVCNLRLQRG-----GMVQNSEQY
|.                                                                     |..  ..  .||.|      |.... |||
lg.....................................................................vsleealedvrlkRpinpnpgfieqleqy

ELIHRAICLYLKR
| |..|.. |||.
efilealleylkf
subfamily_PTPN6_pd Subfamily PTPN6 913-1004 4.7e-14 47.1 In-house 52-126 (306) alignment 
Range on Protein: 913-1004
Range on HMM: 52-126/306.0
FGSQTKNRYKTILPNENSRVLLEsesseltsllgeikrTSSVTASEdlpYINANYIKGP-DYVSKCYVATQGPLPNTIFEFWLMIYQNTQRYI
   ..|||||.||| ...|| |.                .||. |.   ||||||||.     .|.|.|||| |..|. .|| |..|.  | |
penkeknryknilPfDhtrvilk...............epsvpgsd...yinanyikkevkgsdksyiatqgclettvsdFWrmvwqensrvi
0042113 (Phosphotyrosine protein) phosphatases II 914-1054 3.1e-20 68.1 In-house 8-101 (245) alignment 
Range on Protein: 914-1054
Range on HMM: 8-101/245.0
GSQTKNRYKTILPNENSRVLLESesseltsllgeikrtssVTASEDLPYINANYIKGPDYVSKcYVATQGPLPNTIFEFWLMIYQNtqryirrcvdggss
 ...||||. |||....|| | .                 .  ..|..||||.|..|...  | . |||||||.|.  || |....              
enkdknrysdilpydhtrvklsp.................dggdldsdyinasyvdgyritpk.fiatqgPlpetvedfwrmlwel..............

ssphvdreqilqqYFQKIVMLTNFTEANRQKCAVYFPIelN
               . |||||...| .|.||| |.|   .
.............gittivmLteeeelgrvkcaqywpl..g
subfamily_PTPRG_pd Subfamily PTPRG 914-1000 4.6e-12 39.9 In-house 46-115 (563) alignment 
Range on Protein: 914-1000
Range on HMM: 46-115/563.0
GSQTKNRYKTILPNENSRVLLESesseltsLLGeikrtssVtaSEDLPYINANYIKGPdYVSKCYVATQGPLPNTIFEFWLMIYQNT
 .. ||||  |.. ..||| |..       | |       .   ..| |||||||.|  . || ..||||||..|.  || ||... 
enkrKnRylnivaydrsRvklsp.......lpg.......k..kkklDYinAnyidGy.qkskafiatqgplkdtfddFWrmiWeqn
subfamily_Anemone-PTP-5_pd Subfamily Anemone-PTP-5 914-1000 7.8e-11 36.6 In-house 47-115 (319) alignment 
Range on Protein: 914-1000
Range on HMM: 47-115/319.0
GSQTKNRYKTILPNENSRVLLesesseltsllgeikrtSSVTASEDLPYINANYIKGPDYvSKCYVATQGPLPNTIFEFWLMIYQNT
  ..||||. ||. ...|| |                 |..  .|.  ||||..| | .   . ..|||.|| ||| .|| |.... 
enkkknryqnilaydrtrvvl.................seldgvegsdyinasfidgyqe.rekfiatqaPlentiedfWrmvWeee
subfamily_Sponge-PTP5_pd Subfamily Sponge-PTP5 914-1000 8.6e-11 36.3 In-house 32-99 (283) alignment 
Range on Protein: 914-1000
Range on HMM: 32-99/283.0
GSQTKNRYKTILPNENSRVLLESESSeltsllgeikrtssvtasedlPYINANYIK--GPDYVSKCYVATQGPLPNTIFEFWLMIYQNT
  ..|||.. |.| .. || |.|||                       |||| .|     .  .| |...|.|| .|. .|| |.... 
enkrknrnqeivpadqwrvelksesr.....................dyinavfipvsksykqdkkyiiaqsPldrtvvdfWkmvfdek
DSPc_SM00195 915-1004 1.3e-21 72.5 In-house 26-97 (263) alignment 
Range on Protein: 915-1004
Range on HMM: 26-97/263.0
SQTKNRYKTILPNENSRVLLESESSEltsllgeikrtssvtasEDLPYINANYIKGPdYVSKCYVATQGPLPNTIFEFWLMIYQNTQRYI
...||||| |||....|| |..| ..                 |.  |||||||||.   .| |.|||||||.|. .|| |....  ..|
nksknRyknilpydhtrVklkkeekk.................egsdYINAnyikga.nkkkkyIatQgPlpstvedFWrmvweekvkii
PTPc_SM00194 915-1004 1.3e-21 72.5 In-house 26-97 (263) alignment 
Range on Protein: 915-1004
Range on HMM: 26-97/263.0
SQTKNRYKTILPNENSRVLLESESSEltsllgeikrtssvtasEDLPYINANYIKGPdYVSKCYVATQGPLPNTIFEFWLMIYQNTQRYI
...||||| |||....|| |..| ..                 |.  |||||||||.   .| |.|||||||.|. .|| |....  ..|
nksknRyknilpydhtrVklkkeekk.................egsdYINAnyikga.nkkkkyIatQgPlpstvedFWrmvweekvkii
subfamily_Fungi-PTP1_pd Subfamily Fungi-PTP1 915-1002 3.7e-17 57.1 In-house 47-130 (350) alignment 
Range on Protein: 915-1002
Range on HMM: 47-130/350.0
SQTKNRYKTILPNENSRVLLE-SESSEltsllgeiKRTSSVTASEDlpYINANYIKGP----DYVSKC-YVATQGPLPNTIFEFWLMIYQNTQR
. .||||| ||| | ||| |. |  |         .     . ..|  ||||||.| .    .  ..  |.|||.|||.|. .|. .|..|  .
lfaknrYknilPYehsrvkLkkslkss........dakkhslstnD..YinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvk
subfamily_Fungi-PTP2_pd Subfamily Fungi-PTP2 915-1001 1.1e-14 48.5 In-house 48-132 (349) alignment 
Range on Protein: 915-1001
Range on HMM: 48-132/349.0
SQTKNRYKTILPNENSRVLLESESSelTSLLGEIKrTSSVTASEDLPYINANYIKGPDY-VSKCYVATQGPLPNTIFEFWLMIYQNTQ
. .||||| ||| | ||| |.      .|   .   ||   ..    ||||||.| . . | | |.||| ||| |. .|. .|  |  
lfaknrykdilPyehsrvklkkslk..sskvikas.tsesdsgklddyinanylkltrisvekkyiatqaPlPstvddfykvillngv
subfamily_PTPRB_pd Subfamily PTPRB 915-1004 1.1e-14 49.2 In-house 51-122 (293) alignment 
Range on Protein: 915-1004
Range on HMM: 51-122/293.0
SQTKNRYKTILPNENSRVLLESESSEltsllgeikrtssvtasEDLPYINANYIKGPDyVSKCYVATQGPLPNTIFEFWLMIYQNTQRYI
 ..||||. ||| ..||| |.. ..|                 ..  |||||||.|     . ..|||||||.|. .|| |....  . |
nraknrytnilpydhsrvkLaalkde.................sgsDYinanyipgyn.sprefiatqGPlpetvddfWrmvwekkssii
subfamily_Urchin-PTPRB-like_pd Subfamily Urchin-PTPRB-like 915-1003 1.1e-12 42.6 In-house 47-117 (288) alignment 
Range on Protein: 915-1003
Range on HMM: 47-117/288.0
SQTKNRYKTILPNENSRVLLESESSEltsllgeikrtssvtasEDLPYINANYIKGpDYVSKCYVATQGPLPNTIFEFWLMIYQNTQRY
 ..||||. ||| .  || |.    |                 ..  ||||.||.| .  .| |.||||||..|. .|| ..|.|    
nakknRyrnilpyDekrvklkkleee.................agaDYinasyidg.ekkkkkyiatqgPladtvndfWelvyenktst
subfamily_Sponge-PTP11_pd Subfamily Sponge-PTP11 915-1002 5.9e-09 30.2 In-house 46-117 (290) alignment 
Range on Protein: 915-1002
Range on HMM: 46-117/290.0
SQTKNRYKTILPNENSRVLLESESSEltsllgeikrtSSVTASedlpYINANYIKGPDYvSKCYVATQGPLPNTIFEFWLMIYQNTQR
....||...|..... |. |   |..              | .    |||| ||||    .| |.|||||..||. .|| .|.|.   
nkllnRfanivvyddnritLrpisgh...........kDCtne....yinAcyikgyke.kkqyiatqgpvsntlvdFWkliwqekvt
subfamily_Urchin-PTP-3_pd Subfamily Urchin-PTP-3 915-1055 7.1e-09 30.2 In-house 48-142 (325) alignment 
Range on Protein: 915-1055
Range on HMM: 48-142/325.0
SQTKNRYKTILPNENSRVLLESESSEltsllgeikrtS-SvtaseDlpYINANYIKGpDYVSKCYVATQGPLPNTIFEFWLMIYQNTqryirrcvdggss
 . |||.| ... ..||| ||.   .           . |     |  ||||.|..  |   . ..|.| ||..|| ..| ....               
nkaknrfknvvaldksrvvletkkdd...........pss.....d..yinasylrd.dkkkdvflaaqaPltatindlWrlvldWr.............

ssphvdreqilqqyfQKIVMLTNFTEANRQKCAVYFPIELNE
                 .|...|  . . ..||||.| |. .
...............csvvvvlneldlgkdrcavywpkemgk
subfamily_egg_pd Subfamily egg 915-1050 8.2e-09 29.6 In-house 40-128 (307) alignment 
Range on Protein: 915-1050
Range on HMM: 40-128/307.0
SQTKNRYKTILPNENSRVLLESESSELTSllgeikrtssvtasedlPYINANYIKGPDYVSKcYVATQGPLPNTIFEFWLMIYQNTQRYIRRCVDGGSSs
 ..| | | .  .. ||| || .    .                   .| ||..||   . . .. .| || ||  .|| |..|.  .||        | 
nlekarskrvhckdssrvklelrrGqyld.................dfihanrvkGkpllne.filaqaplkntvddfwrmvfqeevqyivmltsrkes.

sphvdreqilqqyfqkivmltnfteanrQKCAVYFP
                            ..|  |.|
............................erceyywp
0041856 (Phosphotyrosine protein) phosphatases II 916-1369 2e-28 94.6 In-house 2-172 (182) alignment 
Range on Protein: 916-1369
Range on HMM: 2-172/182.0
QTKNRYKTILPNENSRvllesesseltsllgeikrtssvtaseDLPYINANYIKGPDYVSKcYVATQGPLPNTIFEFWLMIYQNTQRYIRRCVdggssss
..||||. |||...||                           || |||||.. |. . .. ..||||||..|. .|. |....  ..| ..        
ldknrysdilpydhsr...........................dldyInanlylgslpatr.fiatqgpllstvadflrmlkelgittivnlt.......

phvdreqilqqyfqkivmltnfteanrqkCAVYFPielneifavaakcevfqlsaaardyfdryltptfvpdtvvassdaidyeisgrhigvesvkvtle
                             .  |.|                                                                 
.............................eelywp.................................................................

gdllealpaqgsffliknvgivrrngysvrklvllycirvpqsasyHLQKIYCYHYWYPDWPDHHSPRdINTLLDTCLHVLNlgkcesEfdiyddtrser
                                               | . . ..|.|  ||||. |  ...||| .  ||.      |           
..............................................ellerlgiqylylpwpDhgvpd.ldelldfieevle......e...........

nahlaaqrleiyqqdifnavQPLPVIHCSAGIGRTGCFTAILNAVRQlRQSlaysltgmltksltsssteeyhnptdsdssftcntirhishildhrdae
                    .   ..|||||.||||.. |.    .. . |                                                 
....................ggpvlVHCsaGvgRtgtlvaaylmkkl.gvs.................................................

avktppsfdrlpkmpdifvdVLGIVCNLRLQRGGMVQNSEQYELIHRAICLYLK
                    .  .|. .| .| |||.. .|| ....|....|.
....................leeavklvrsrRpgmvitpnqyfflqlallelll
Y_phosphatase Protein-tyrosine phosphatase 916-1004 1.3e-18 62.6 Pfam-A 2-70 (235) alignment 
Range on Protein: 916-1004
Range on HMM: 2-70/235.0
QTKNRYKTILPNENSRVLLesesseltsllgeikrtSSVTASEDlpYINANYIKGPDyVSKCYVATQGPLPNTIFEFWLMIYQNTQRYI
..|||||.||| ...|| |                 .. . ..|  ||||||.|| .  .| ..||||||..|| .|| |..|.  ..|
kkknRykdilpydktrvkl.................kgsegpsd..YInAnyvkgyk.ekkkfIatQgPlkstiedFWrmvwqekvkvi
Y_phosphatase Protein-tyrosine phosphatase 916-1004 1.3e-18 62.6 In-house 2-70 (235) alignment 
Range on Protein: 916-1004
Range on HMM: 2-70/235.0
QTKNRYKTILPNENSRVLLesesseltsllgeikrtSSVTASEDlpYINANYIKGPDyVSKCYVATQGPLPNTIFEFWLMIYQNTQRYI
..|||||.||| ...|| |                 .. . ..|  ||||||.|| .  .| ..||||||..|| .|| |..|.  ..|
kkknRykdilpydktrvkl.................kgsegpsd..YInAnyvkgyk.ekkkfIatQgPlkstiedFWrmvwqekvkvi
subfamily_PTPN12_pd Subfamily PTPN12 916-999 2.2e-16 54.6 In-house 41-106 (290) alignment 
Range on Protein: 916-999
Range on HMM: 41-106/290.0
QTKNRYKTILPNENSRVLLESESSELtsllgeikrtssvtaseDLPYINANYIKGPDyVSKCYVATQGPLPNTIFEFWLMIYQN
..||||| ||| ..||| |. ...|                  .  |||||.|||..  .. |.|.|||||.|. .|| ||.. 
vkknrykDilPydksrvelskieeee.................gsdYinanfikgve.gkleyiaaqgPLpktlddfWrmiwek
subfamily_Choan-PTP-1_pd Subfamily Choan-PTP-1 916-1003 5.1e-13 43.8 In-house 42-111 (281) alignment 
Range on Protein: 916-1003
Range on HMM: 42-111/281.0
QTKNRYKTILPNENSRVLLESESSELtsllgeikrtssvtaseDLPYINANYIKGPDyVSKCYVATQGPLPNTIFEFWLMIYQNTQRY
..||||. |   ...|| .. ....                  .  |||||...| .   | |.|||||.|... .|| |..... . 
vlknrYsnivaYDatrvkvtpneenk.................ntDYinanfvpgyk.gekeyiatqgPvPaslvafWqmvweqkvsa
subfamily_Nvec-PTP-2_pd Subfamily Nvec-PTP-2 916-1002 1.9e-11 38.7 In-house 10-78 (250) alignment 
Range on Protein: 916-1002
Range on HMM: 10-78/250.0
QTKNRYKTILPNENSRVLLESESSEltsllgeikrtssvtasEDLPYINANYIKGPDYVsKCYVATQGPLPNTIFEFWLMIYQNTQR
. ||||  |.. ..|||.||.|...                 ..  |||| ...| |   | ..||||||..|| .|| |....   
keknryadiialdssrvvLekekgd.................kesdyinasflhgyder.kafiatqgPlqatiedfWrmvleeksg
subfamily_PTPN13_pd Subfamily PTPN13 916-1003 4.1e-11 37.7 In-house 38-104 (273) alignment 
Range on Protein: 916-1003
Range on HMM: 38-104/273.0
QTKNRYKTILPNENSRVLLESESSeltsllgeikrtssvtasedlpYINANYIKGP-DYVSKCYVATQGPLPNTIFEFWLMIYQNTQRY
..||||. .|| ...|| |..|..                      ||||..|| | .     |.|.|||||.|. .||.|... . . 
kdknryrnvlPydetrvklgdegg......................yinaslikvpvgkdeyeyiacqGPlPetvkdfwqmvweqkaev
subfamily_Sponge-PTP10_pd Subfamily Sponge-PTP10 916-1001 1.6e-10 35.4 In-house 48-111 (287) alignment 
Range on Protein: 916-1001
Range on HMM: 48-111/287.0
QTKNRYKTILPNENSRVLLEsesseltsllgeikrtssvtaSEDLPYINANYIKGPDyVSKCYVATQGPLPNTIFEFWLMIYQNTQ
. |||.. ||. .| ||||.                      |.  |||| .|.|    .| ......|. ||. .|| .| ..  
kdknRltqilvpdnyrvllk.....................gehpdyinavfidgyk.ekkafiiaesPmfntarnfWkliddrnv
subfamily_Urchin-PTP-6_pd Subfamily Urchin-PTP-6 916-1000 1.1e-09 31.9 In-house 44-110 (515) alignment 
Range on Protein: 916-1000
Range on HMM: 44-110/515.0
QTKNRYKTILPNENSRVLLESesseltsllgeikrtssVTASEDLPYINANYIKGPDyVSKCYVATQGPLPNTIFEFWLMIYQNT
 .||||| ||| ...|| ||                  .  . .  |.|| ||.. |   |.|.|.|||.. .. .|| ...|. 
fkknryknilPydsvrvklev.................indnPhsdyfnasyipsfd.ndkayiasqgPnkasvddfWrlvlqen
subfamily_Anemone-PTP-4_pd Subfamily Anemone-PTP-4 916-1000 2.2e-09 31.9 In-house 4-69 (237) alignment 
Range on Protein: 916-1000
Range on HMM: 4-69/237.0
QTKNRYKTILPNENSRVLLESESSEltsllgeikrtssvtasedLPYINANYIKGPDYVSKCYVATQGPLPNTIFEFWLMIYQNT
. ||||  |   . |||.|.   |.                     ||||.|.|| |   | |.|.|||| ..  .|| |..|. 
kiknrygnivaydhsrvvlkgagsg...................sdyinatylkgfdgtpkkyiaaqgplesscddfwqmvwqek
subfamily_Choan-PTP-3_pd Subfamily Choan-PTP-3 916-1000 3.7e-09 30.8 In-house 39-104 (287) alignment 
Range on Protein: 916-1000
Range on HMM: 39-104/287.0
QTKNRYKTILPNENSRVLLESESsEltslLGeikrtSSvtasedlpYINANYIKGPDyVSKCYVATQGPLPNTIFEFWLMIYQNT
  ||||  .|| ...||||  |. |    ||     |.        ||||||. .     . ..|.|||.. |. .|| ..... 
vkknryadvlPiddtrvllsaeg.e....lG.....sd........yinanyvasyt.ddeafiaaqgPiaatvrdfwravletr
subfamily_Urchin-PTP-7_pd Subfamily Urchin-PTP-7 916-999 1.2e-08 29.3 In-house 50-115 (315) alignment 
Range on Protein: 916-999
Range on HMM: 50-115/315.0
QTKNRYKTILPNENSRVLLEsesseltslLGEIKRTSSvtasedlpYINANYIKGPDYVsKCYVATQGPLPNTIFEFWLMIYQN
. ||||  |.. ..||| |          | | .  |         |.|||.|.| ..  . |.|.|||..... .|| .....
kqknryiniiaydksrvqlp.........llendphsd........yvnanfidGynkk.rryiaaqgpnvasvkdfwrlvfee
subfamily_Sponge-PTP1_pd Subfamily Sponge-PTP1 916-1000 1.1e-06 22.8 In-house 34-96 (267) alignment 
Range on Protein: 916-1000
Range on HMM: 34-96/267.0
QTKNRYKTILPNENSRVLLESESSEltsllgeikrtssvtasedlpYINANYIKGPdYVSKCYVATQGPLPNTIFEFWLMIYQNT
| .||.   || ...|| |  .  |                     |||| |..|  .  . ...||.|| ||| .|. .| .. 
qernrlddnlpyddtrvilrtkeee.....................yinasyvegy.ktknafivtqdplkntitdfltvihdqk
subfamily_PTPN14_pd Subfamily PTPN14 916-1002 1.2e-06 22.7 In-house 50-119 (300) alignment 
Range on Protein: 916-1002
Range on HMM: 50-119/300.0
QTKNRYKTILPNENSRVLLESEsseltsllgeiKRT--SsvtasedlpYINANYIKGPDY-VSKCYVATQGPLPNTIFEFWLMIYQNTQR
. |||.| .|| |..|| | .            | .            ||||  || .    .. |...||||..|. .|| |....  .
aeknrfkdvlPyednrvelspt...........kenstg.........yinassikvsvggkersyivaqgPleltvqdfWqmvWeqgvq
subfamily_Anemone-PTP-1_pd Subfamily Anemone-PTP-1 916-1001 1.5e-06 22.5 In-house 9-77 (239) alignment 
Range on Protein: 916-1001
Range on HMM: 9-77/239.0
QTKNRYKTILPNENSRVLLESESSELTSllgeikrtssvtasEdlpYINANYIKGPDYVSKCYVATQGPLPNTIFEFWLMIYQNTQ
..||||  |.  . |||.||  | .  |              .   ||||.|..  |   |.|.|||| .  .  .|| |..|. .
kaknryanivtydhsrvvleklsndphs..............d...yinasylrdydgspkayiatqgcveissgdfwrmmwqerr
subfamily_Nvec-PTP-1_pd Subfamily Nvec-PTP-1 916-1001 1.6e-06 22.5 In-house 8-76 (239) alignment 
Range on Protein: 916-1001
Range on HMM: 8-76/239.0
QTKNRYKTILPNENSRVLLESESSELTSllgeikrtssvtasEdlpYINANYIKGPDYVSKCYVATQGPLPNTIFEFWLMIYQNTQ
..||||  |.  . |||.||  | .  |              .   ||||.|..  |   |.|.|||| .  .  .|| |..|. .
kaknryanivtydhsrvvleklsndphs..............d...yinasylrdydgspkayiatqgcveissgdfwrmmwqerr
subfamily_Sponge-PTP6_pd Subfamily Sponge-PTP6 916-1000 2.9e-06 21.0 In-house 49-115 (439) alignment 
Range on Protein: 916-1000
Range on HMM: 49-115/439.0
QTKNRYKTILPNENSRVLLEsesseltsllgEikrTSSVTASEdlpYINANYIKGpDYVSKCYVATQGPLPNTIFEFWLMIYQNT
||||||| . . . .|| |.           |   .  |  |    |||||||||  |  | |.|||||  .|  .|| ..... 
qtknrykdvgafdhtrvtlq...........e...ipgvphsh...yinanyikG.yyddklyiatqgpkkettddfwrlviekk
subfamily_PTPN23_pd Subfamily PTPN23 917-1004 4.9e-14 46.8 In-house 45-111 (288) alignment 
Range on Protein: 917-1004
Range on HMM: 45-111/288.0
TKNRYKTILPNENSRVLLEsesseltsllgeikrtssvtASEDlPYINANYIKGPDYVSKCYVATQGPLPNTIFEFWLMIYQNTQRYI
.|||.. ||| ...|| |.                     |.|  |||| ..|.   .. ...|||.||..|. .||||.|..  . |
eknrsrdilPyDhnRvklr....................gskD.DYinAsfvkdlspgcPdfiatqaPlqstlnDFWlmvyeqkssvi
subfamily_Urchin-PTPRA_pd Subfamily Urchin-PTPRA 917-1007 5.6e-11 37.3 In-house 63-136 (319) alignment 
Range on Protein: 917-1007
Range on HMM: 63-136/319.0
TKNRYKTILPNENSRVLLEsesseltsllgeikRTSSVTASEdlpYINANYIKGPDYvSKCYVATQGPLPNTIFEFWLMIYQ-NTQRYIRRC
 |||.  ||. ....| ||              |.  .  |.   |||| ...|     . |.|.||||.||. .|| ||.. |.  ..   
dknriinilafdknvvkle..............rliGeefsd...yinasfvtGyqr.kdkyiaaqGPldntladfWrmiweyncstivllt
subfamily_ptpA1_pd Subfamily ptpA1 917-1004 1e-10 35.9 In-house 49-117 (418) alignment 
Range on Protein: 917-1004
Range on HMM: 49-117/418.0
TKNRYKTILPNENSRVLLesesseltsllgeiKRtssVTASEDLPYINANYIKGPdYvSKCYVATQGPLPNTIFEFWLMIYQNTQRYI
.||||  ||| . .|| |              |.   .   |   ||||||| |  |  | ...||||||||| .|| |...|  | |
sknrytnilpvnhtrvql..............kk...iqdkegsdyinanyidga.y.pkqfictqgplpntiadfwrmvwenrcrii
subfamily_PTPRK_pd Subfamily PTPRK 917-1000 1.7e-09 31.9 In-house 45-110 (314) alignment 
Range on Protein: 917-1000
Range on HMM: 45-110/314.0
TKNRYKTILPNENSRVLLESesseltsLLGEikrTSSvtasEdlpYINANYIKGPDyVSKCYVATQGPLPNTIFEFWLMIYQNT
.|||.. ||. ..||| | .       . |.   .||    .   ||||..| .    .. ...|||||..|. .|| ..|.. 
eknrsgdilaydrsrvflit.......idgd...pss....d...yinaalidsyk.rpaafivtqgPlqetvkdfWrlvyden
subfamily_PTPRN_pd Subfamily PTPRN 917-1000 5.9e-09 30.0 In-house 58-124 (297) alignment 
Range on Protein: 917-1000
Range on HMM: 58-124/297.0
TKNRYKTILPNENSRVLLESESSEltsllgeikrtssvtasEDLPYINANYIKGPDYVSKCYVATQGPLPNTIFEFWLMIYQNT
.|||.|..|| ..||| |..|.|.                 |.  ||||  |   |  . .|.||||||..|. .|| |.... 
kknrskavlpydhsrvklkeeasa.................eksdyinasaildhdprapayiatqgplastvadfwqmvweqG
subfamily_Cele-PTP-17_pd Subfamily Cele-PTP-17 917-997 2.6e-07 24.5 In-house 39-106 (347) alignment 
Range on Protein: 917-997
Range on HMM: 39-106/347.0
TKNRYKTILPNENSRVLLESESSELTsllgeikRTSSVTAsedlpYINANYIKGpDYVSKCYVATQGPLPNTIFEFWLMIY
.||| |    ....||.|  | |. .       |.  | .     |||| .||  |  || |. || |||.|. .|| |..
sknrskdvklidatrvvlspekskns.......raddvet.....yinashikf.dnaskeyiltqyplpdtvrdfwkmvs
subfamily_CG7180_pd Subfamily CG7180 917-1001 2.2e-06 21.6 In-house 44-110 (296) alignment 
Range on Protein: 917-1001
Range on HMM: 44-110/296.0
TKNRYKTILPNENSRVLLESesseltsLLGEikrtssvtASEDlpYINANYIKGPdYVSKCYVATQGPLPNTIFEFWLMIYQNTQ
 |||. ...| .. ||.||.       | ||        ...|  |||| |. .     | |. |..|  .|. ||| ..|..  
eknrdvkvvPyDynRvvLek.......ldGe........eksd..Yinavyvdsf.lkkkeyivteapkketvdefWrlvydeei
subfamily_Cele-PTP-15_pd Subfamily Cele-PTP-15 948-1004 1.4e-09 32.4 In-house 47-103 (285) alignment 
Range on Protein: 948-1004
Range on HMM: 47-103/285.0
IKRTSSVTASEDLPYINANYIKGPDYVSKCYVATQGPLPNTIFEFWLMIYQNTQRYI
|. |  |    |  || |.... |      |..||||||.|. .|| ||||.   |.
ieetrvvlknhdrdyihaswmrmpgkdqstyittqgplpetlsdfwhmiyqekiayv
subfamily_Sponge-PTP8_pd Subfamily Sponge-PTP8 953-1004 2.8e-11 38.1 In-house 64-117 (305) alignment 
Range on Protein: 953-1004
Range on HMM: 64-117/305.0
SVTASED---LPYINANYIKGPDyVSKCYVATQGPLPNTIFEFWLMIYQNTQRYI
 .|..|.     ||||.|..| .  .|.|...||||.||. .|| .|..   . |
iltekeslddsdyinasyvdgyk.rkkkyivaqgPlkntvadfWrliveekvsti
subfamily_CG42327_pd Subfamily CG42327 955-1005 2.3e-07 24.8 In-house 51-101 (319) alignment 
Range on Protein: 955-1005
Range on HMM: 51-101/319.0
TASEDLPYINANYIKGPDYVSKCYVATQGPLPNTIFEFWLMIYQNTQRYIR
.  .   |..|.|..|.|     |.|.| .| ..  .|| .....  | | 
gdddkdeyldasyvrGyddapnsyiaaqvsledsssdfwrtvweqqsrviv
subfamily_Choan-PTP-4_pd Subfamily Choan-PTP-4 955-1004 5e-07 23.9 In-house 56-104 (297) alignment 
Range on Protein: 955-1004
Range on HMM: 56-104/297.0
TASEDlpYINANYIKGPDYVSK-CYVATQGPLPNTIFEFWLMIYQNTQRYI
 . .|  ||||.|.  ||  ..  |. .|||| .|. .|| .....  | |
iterd..yinadyvvfpdeeadlkyilaqGplsatvddfwtlvaeqdvrvi
subfamily_Urchin-PTP-8_pd Subfamily Urchin-PTP-8 956-1007 6.5e-11 37.2 In-house 49-100 (284) alignment 
Range on Protein: 956-1007
Range on HMM: 49-100/284.0
ASEDLPYINANYIKGPDYvSKCYVATQGPLPNTIFEFWLMIYQ-NTQRYIRRC
  |   |||| .|.|     . |.||||||.||. .|| ||.. |.  ..   
GeefsdyinasfitGyqr.kdkyiatqGPldntladfWrmiweyncstivllt
subfamily_Cele-PTP-14_pd Subfamily Cele-PTP-14 957-1004 9.1e-09 29.3 In-house 76-122 (310) alignment 
Range on Protein: 957-1004
Range on HMM: 76-122/310.0
SEDLPYINANYIKGpDYVSKCYVATQGPLPNTIFEFWLMIYQNTQRYI
|    || |||.|  .|. . .. .||||  || .|| ||.|.    |
sryedyihanyvkt.nylrstficsqgplqhtiidfwrmifqeraesi
subfamily_PTPN3_pd Subfamily PTPN3 957-1004 1.3e-08 29.1 In-house 63-112 (280) alignment 
Range on Protein: 957-1004
Range on HMM: 63-112/280.0
SEDlPYINANYIK--GPD-YVSKCYVATQGPLPNTIFEFWLMIYQNTQRYI
||   ||||||..   |   ... |.||||||..|  .|| |..... . |
set.dyinanyvnmeipstglvnryiatqGPlaktatdfWqmvweqkssli
0044763 (Phosphotyrosine protein) phosphatases II 958-1365 2.5e-15 52.0 In-house 16-168 (178) alignment 
Range on Protein: 958-1365
Range on HMM: 16-168/178.0
EDLPYINANYIKGPdyvskCYVATQGPlpntifefwlmiyqntqryirrcvdggsssspHVDREQILQQYFQKIVMLTNFTEANRQKCAVYFPIELNeif
|  .||||..| .       |.....|                                  |.|.. .. .. ||.||. .| ...||  |.| | .   
ersdyinaseilpg.....lylgslpp................................addlellkelgithivnlteelelgflkcdpywpeeag...

avaakcevfqlsaaardyfdryltptfvpdtvvassdaidyeisgrhigvesvkvtlegdllealpaqgsffliknvgivrrngysvrklvllycirvpq
                                                                                                    
....................................................................................................

sasyhlqkiycYHYWYPDWPDHHSPRdINTLLDTCLHV----LnlgkcesefdiyddtrsernahlaaqrleiyqqdifNAVQPLPVIHCSAGIGRTGCF
           ..| .  .|||. |  .   .. ...     |                                    .  .   ..|||||.||.|..
...........iqylhipipDhgvpd.llehflefvefieeal....................................dekggpvlVHCsaGvgRsgtl

TAI-LNAVRQlrqslaysltgmltksltsssteeyhnptdsdssftcntirhishildhrdaeavktppsfdrlpkmpdifVDVLGIVCNLRLQRGgMVQ
 |. |  ...                                                                       ...  ..  .| .|  .|.
vaaylmkklg.......................................................................lsleeaielvrerRp.ivp

NSEQYELIHRAIC
| .|.. ...   
npgqlrqLyefel
subfamily_Cele-PTP-13_pd Subfamily Cele-PTP-13 958-1001 5.6e-07 23.5 In-house 64-106 (281) alignment 
Range on Protein: 958-1001
Range on HMM: 64-106/281.0
EDLPYINANYIKGPdYVSKCYVATQGPLPNTIFEFWLMIYQNTQ
.   || ||||. | .. . |. ||||  .|  .|| ||.|.  
nstdyihanyirsp.flkrgyiltqgpkketradfwrmiwqent
0046846 (Phosphotyrosine protein) phosphatases II 958-1005 7.3e-06 21.4 In-house 10-52 (176) alignment 
Range on Protein: 958-1005
Range on HMM: 10-52/176.0
EDLPYINANYIKGPdyvskCYVATQGPLPNTIFEFWLMIYQNTQRYIR
.|| |||||.| |.     ...|||||||.|. .|. |....  ... 
ldldyinanlilgs.....rpiatqgplprtladflemlkelgitavv
0043147 (Phosphotyrosine protein) phosphatases II 959-1259 6.6e-18 60.5 In-house 4-123 (172) alignment 
Range on Protein: 959-1259
Range on HMM: 4-123/172.0
DLPYINANYIKGPDYVSKcYVATQGPLPNTIFEFWLMIYQNTQRYIRRCVDGgssssphvdreqilqqyfqkivmltnfteanrqkcavyfpielneifa
.  ||||.|....    . ..||||||.||. .|| |....  ..| .. .                                                 
gsdyinasyldlyyipdr.fiatqgplrntladfwrmlkelgithivnltel................................................

vaakcevfqlsaaardyfdryltptfvpdtvvassdaidyeisgrhigvesvkvtlegdllealpaqgsffliknvgivrrngysvrklvllycirvpqS
                                                                                                    
...................................................................................................l

ASYHLQKIYCYHYWYPDWPDHHSPrDINTLLDTCLHVLNLGkCESEfdiyddtrsernahlaaqrleiyqqdifnavQPLPVIHCSAGIGRTGCFTAILN
  . | . . ..|.|  ||||. | ... ||...  . .|  ..|.                               .   ..|||||.||||.. |.. 
ydpellerlgiqylylpwpDhgvp.llellleflefidell.alsp...............................ggpvlVHCsaGvgRtgtlvaayl

A
 
m
subfamily_Sponge-PTP9_pd Subfamily Sponge-PTP9 959-1005 9.5e-08 26.1 In-house 69-114 (301) alignment 
Range on Protein: 959-1005
Range on HMM: 69-114/301.0
DLPYINANYIKGPDYvSKCYVATQGPLPNTIFEFWLMIYQNTQRYIR
   ||||.||.|    .| ..|.|||. .|. .|| .|.|. .  | 
qreyinasyidgyse.kkkfiaaqgpmkktlvdfWrliwqekpvsiv
subfamily_Cele-PTP-10_pd Subfamily Cele-PTP-10 959-1002 2.1e-07 24.9 In-house 79-122 (305) alignment 
Range on Protein: 959-1002
Range on HMM: 79-122/305.0
DLPYINANYIKGPDYVSKCYVATQGPLPNTIFEFWLMIYQNTQR
   || |||.  |    | ....|||| .|| ||| |. ||   
psdyihanyvgcpmipekrficaqgpldqtidefwwmviqnkve
0051082 (Phosphotyrosine protein) phosphatases II 961-1260 6.5e-13 44.0 In-house 4-116 (151) alignment 
Range on Protein: 961-1260
Range on HMM: 4-116/151.0
PYINANYIKGPdyvskcYVATQGPLPntifefwlmiyqntqryirrcvdggssssphVDREQILQQYFQKIVMLTNFTEANrqKCAVYFPIELneifava
.|||..|. |       . ...|||.                                . |.. .. .. ||.|.. .| .  .|. |.| .        
dyinfsyvtgg......lyrsggpla...............................dflellkelgiktivnlrseeerg..ycpeylpelg.......

akcevfqlsaaardyfdryltptfvpdtvvassdaidyeisgrhigvesvkvtlegdllealpaqgsffliknvgivrrngysvrklvllycirvpqsas
                                                                                                    
....................................................................................................

yhlqkIYCYHYWYPDWPDHHsprdintlldtclhvlnlgkcesefdiyddtrsernA----HLAAQRLEIYQQdifnaV-QPLPVIHCSAGIGRTGCFTA
     |  .|....||||.                                          . ... ||....       .   ..|||||.||||.. |
.....ievlhipildwpdpg....................................lplsfdavleflellld.....kkngpvlvHCsaGkgRTGtlva

ILNAV
..   
lylml
subfamily_Cele-PTP-18_pd Subfamily Cele-PTP-18 961-1004 8.2e-06 19.7 In-house 74-116 (305) alignment 
Range on Protein: 961-1004
Range on HMM: 74-116/305.0
PYINANYIKGPDYvSKCYVATQGPLPNTIFEFWLMIYQNTQRYI
 || |||.  |   .| .. || || .|  .|| | .|.   .|
eyihanyvstptn.pkrfictqaplektcadfwymclqdkveai
0036282 (Phosphotyrosine protein) phosphatases II 962-1361 1.3e-19 66.0 In-house 4-163 (174) alignment 
Range on Protein: 962-1361
Range on HMM: 4-163/174.0
YINANYIKGpDYVSKCYVATQGPLPntifefwlmiyqntqryirrcvdggssssphvDREQILQQYFQKIVMLTNFTEANRQKCAVYFPIelneifavaa
||||.....  |... ..|.||||.                                . |.. .. .. .|||..  | .. ||  |.|           
yinaspldl.syitprliagqgpla................................fwemlkelgittvvmlleekelglykcinywpe..........

kcevfqlsaaardyfdryltptfvpdtvvassdaidyeisgrhigvesvkvtlegdllealpaqgsffliknvgivrrngysvrklvllycirvpqsaSY
                                                                                                   .
..................................................................................................lr

HLQKIYCYHYWYPDWPDHHSPRDINtLLDTCLHVLNLGkcesefdiyddtrsernahlaaqrleiyqqdifnA--VQPLPVIHCSAGIGRTGCFTAILNA
.  . . ..|.|  ||||. | .   ||. .  | .                                    .   .   ..|||||.||||.. |..  
edlerlgiqylylpwpDhgvpdlsi.llefvkfveeal..................................sedpggpvlVHCsaGvgRtGtlvaaylm

VRQLRQSLAYSltgmltksltsssteeyhnptdsdssftcntirhishildhrdaeavktppsfdrlpkmpdifvdvLGIVCNLRLQRGGMVQNSEQYEL
 |.|..||                                                                     | .|  |||||.||||. .||. 
lrglleslvda..................................................................ldlvrelRlqrpgmvqtpsQyrf

IH
..
ly
0046846 (Phosphotyrosine protein) phosphatases II 1009-1370 5.5e-19 64.1 In-house 29-175 (176) alignment 
Range on Protein: 1009-1370
Range on HMM: 29-175/176.0
DGGSSSSPHVDREQILQQYFQKIVMLTNFTEANRQKCAVYFPIELNEIFavaakcevfqlsaaardyfdryltptfvpdtvvassdaidyeisgrhigve
.|.  ..   . |..... .. .|.||. .| .| ||. |.|.. .. .                                                   
qgplprtladflemlkelgitavvnlteevelgrlkcpnywpeleklgi...................................................

svkvtlegdllealpaqgsffliknvgivrrngysvrklvllycirvpqsasyhlqkiycyHYWYPDWPDHHSPRDiNTLLDTCLHVLNLGK---Cesef
                                                             .|.. .||||. | . . ||. .  . .  |   .    
.............................................................qylhlpwpDhgvpdl.elllellefirealkeggp....

diyddtrsernahlaaqrleiyqqdifnavqplPVIHCSAGIGRTGCFTAILNAvrqlrqslaysltgmltksltsssteeyhnptdsdssftcntirhi
                                  ..||||||||||.. |..                                                
.................................vlVHCsaGigRtgtlvaayll..............................................

shildhrdaeavktppsfdrlpkMPDIFVDVLGIVCNLRLQRG-GMVQNSEQYELIHRAICLYLKR
                       . . ...|. ... .| ||  |.||. |||. ......|.||.
.......................elekglsveealalvreqRplgavqtpeQyrflyefellllkk
0049260 (Phosphotyrosine protein) phosphatases II 1015-1258 1.1e-12 43.4 In-house 21-111 (152) alignment 
Range on Protein: 1015-1258
Range on HMM: 21-111/152.0
SPHVDREQILQQYFQKIVMLTNFTEANRQKCAVYFpielneifavaakcevfqlsaaardyfdryltptfvpdtvvassdaidyeisgrhigvesvkvtl
.   . ... ..  . |||||...| .. ||. |.                                                                 
tladfwrmlkelgittivmltellelgklkceqyi.................................................................

egdllealpaqgsffliknvgivrrngysvrklvllycirvpqsasyhlqkiycyHYWYPDWPDHHSPRDINTLLDTCLHVLNLGKCESEfdiyddtrse
                                                       .| .  ||||. | ..  ||. .| .  | . ...          
.......................................................qylhlpwpDhgvpdlsqlllflllfieklaldkgg..........

rnahlaaqrleiyqqdifnavqpLPVIHCSAGIGRTGCFTAILN
                         ..|||||.||||.. |.. 
.......................pvlVHCsaGvgRtgtlvaayl
0051429 (Phosphotyrosine protein) phosphatases II 1017-1373 1.7e-18 62.7 In-house 35-230 (272) alignment 
Range on Protein: 1017-1373
Range on HMM: 35-230/272.0
HVDREQILQQYFQKIVMLTNFTEANRQKCAVYFPielneifavaakcevfqlsaaardyfdryltptfvpdtvvassdaidyeisgrhiGVESVKVTLEG
. | ... ..    ||.|.. .| .|.||  | |                                                       |.. . . ...
aadfwrlkelgiktivdLrseeErgrlkcdrywp.......................................................girylhlpild

DLLEALPaqGSFFLIKNVGIVRRNGYSVRKLVLLYCIRVPQSasyhlqkIYCYHYWYPDWPDHHSPRD-INTLLDTClhvlnlgkcesefdiyddtrser
|  .       .. .... ..  . | .|.|.| ...   ..          .|..| |||||. |.. . .||. .                       
dsaptil..ygalrvtllseellldyilrellltlllsagea.......revmhlhytdwpdhgvpqeallellell.......................

nahlaaqrleiyqQDifnavQPLPVIHCSAGIGRTGCFTAILNAVRQlrqslaysltgmltksltsssteeyhnptdsdssftcntirhishildhrdae
             .|     .   ..|||||..|||.. |.|  ...                                                     
.............ld.....ggpvlvHCsaGkdRTGtvvallllllg.....................................................

avktppsfdrlpkmpdifVD--------------VLGIVCNLRLQRGGMVQNSEQYELIHRAICLYLKRTLA
                  |.              ....|  || || |.||. |||. ...|.  .|.. |.
..................vsletivddYlltnlyleeaveelraqrpgavqteeqylflyeallellrslls
subfamily_Cele-PTP-9_pd Subfamily Cele-PTP-9 1021-1056 4.5e-06 20.9 In-house 46-81 (255) alignment 
Range on Protein: 1021-1056
Range on HMM: 46-81/255.0
EQILQQYFQKIVMLTNFTEANRQKCAVYFPIELNEI
..| |.  ...|||..|.|....||  |||.|..| 
qtivqtktevvvmlcdfaeegvekcssyfplekdek
subfamily_hpo-7_pd Subfamily hpo-7 1022-1056 4.9e-06 20.6 In-house 53-87 (263) alignment 
Range on Protein: 1022-1056
Range on HMM: 53-87/263.0
QILQQYFQKIVMLTNFTEANRQKCAVYFPIELNEI
 | |.  ...|||..|.|....||  |||.|..| 
tivqtktevvvmLcDfneegvekcssyfPlekdek
DSPc_SM00195 1023-1368 5.2e-26 86.9 In-house 89-262 (263) alignment 
Range on Protein: 1023-1368
Range on HMM: 89-262/263.0
ILQQYFQKIVMLTNFTEANRQKCAVYFPIELneifavaakcevfqlsaaardyfdryltptfvpdtvvasS------------------Daidyeisgrh
....  . |||||.. | ...||. |.| |                                                           .          
vweekvkiivmlteeeengkekcdrywpees.......................................ggketfgkisvklvevekkk..........

igvesvkvtlegdllealpaqgsffliknvgivrrNGYSVRKLVLLYCIRvpqsasyhLQKIYCYHYWYPDWPDHHSPRDINTLLDTCLHVLNLGKCEse
                                   . . .|.| | .. .         ..  ...|.| .||||  | . . .|.    | .  . .  
...................................deiilrtleltkegk........eetrkvtqyqyknWpdhgvpdstksvlellravkksksts..

fdiyddtrsernahlaaqrleiyqqdifnavQPLPVIHCSAGIGRTGCFTAILNAVRQLRQSLAysltgmltksltsssteeyhnptdsdssftcntirh
                               ..  |.|||||.||||.| .|  ....|..                                       
...............................sgpivVhCsaGvgRtgtfvtidiilskleeekk....................................

ishildhrdaeavktppsfdrlpkmpdifVDVLGIVCNLRLQRGGMVQNSEQYELIHRAICLYL
                             ||.  ||..|| || ||||..|||  |..||  |.
.............................vdifeivkelRkqRpgmvqtleqYlfiyeaileyi
PTPc_SM00194 1023-1368 5.2e-26 86.9 In-house 89-262 (263) alignment 
Range on Protein: 1023-1368
Range on HMM: 89-262/263.0
ILQQYFQKIVMLTNFTEANRQKCAVYFPIELneifavaakcevfqlsaaardyfdryltptfvpdtvvasS------------------Daidyeisgrh
....  . |||||.. | ...||. |.| |                                                           .          
vweekvkiivmlteeeengkekcdrywpees.......................................ggketfgkisvklvevekkk..........

igvesvkvtlegdllealpaqgsffliknvgivrrNGYSVRKLVLLYCIRvpqsasyhLQKIYCYHYWYPDWPDHHSPRDINTLLDTCLHVLNLGKCEse
                                   . . .|.| | .. .         ..  ...|.| .||||  | . . .|.    | .  . .  
...................................deiilrtleltkegk........eetrkvtqyqyknWpdhgvpdstksvlellravkksksts..

fdiyddtrsernahlaaqrleiyqqdifnavQPLPVIHCSAGIGRTGCFTAILNAVRQLRQSLAysltgmltksltsssteeyhnptdsdssftcntirh
                               ..  |.|||||.||||.| .|  ....|..                                       
...............................sgpivVhCsaGvgRtgtfvtidiilskleeekk....................................

ishildhrdaeavktppsfdrlpkmpdifVDVLGIVCNLRLQRGGMVQNSEQYELIHRAICLYL
                             ||.  ||..|| || ||||..|||  |..||  |.
.............................vdifeivkelRkqRpgmvqtleqYlfiyeaileyi
subfamily_Ptp69D_pd Subfamily Ptp69D 1023-1265 1.4e-10 35.8 In-house 111-248 (307) alignment 
Range on Protein: 1023-1265
Range on HMM: 111-248/307.0
ILQQYFQKIVMLTNFTEANRQKCAVYFPIELNEIFAvAAKCEVFQlSAAARDYFDRYLTPTFVPDTVVASsdaidyeisgrhigvesvkvtlegdlleal
| .|  . ||||.| || ||.||| |.||| .  .      .. . .  . ||  | |  . . ...                                 
iaeqevtlivmlsnlteknrkkcakYWpiedevqyg.dilvklvs.eekhsdyiiReldvskkkeesgev..............................

paqgsffliknvgivrrngysvrklvllycirvpqsasYHLQKIYCYHYwyPDWPDHHSPRDINTLLDTCLHVLNLGKCEsefdiyddtrsernahlaaq
                                       . .|.  |||    |.| . |.  ..||.   .| .| | .                    
......................................edsrkvvqyhy..tgWkDskvPevargllklieqvrelykln....................

rleiyqqdifnaVQPLpVIHCSAGIGRTGCFTAILNAVRQLRQ
              |. |.||||| ||.| | |.   . ||..
............rsPi.vvhCsaGvgrsgifvaldsllqqlka
subfamily_PTPN6_pd Subfamily PTPN6 1023-1192 1.6e-07 25.7 In-house 118-212 (306) alignment 
Range on Protein: 1023-1192
Range on HMM: 118-212/306.0
ILQQYFQKIVMLTNFTEANRQKCAVYFPIELNEIFavAAKCEVFQLSAAardyfdryltptfvpdtvvassdaidyeisgrhigvesvkvtlegdlleal
..|.  . |||.|. .| ...||| |.| | ..      | .| ..|                                                     
vwqensrvivmttkevErgkekCarYWPdeeekee..yGkisvtnvsek...................................................

paqgsffliknvgivRRNGYSVRKLVLLYCirvpqSASYHLQKIycYHYWYPDWPDHHSPRDINTLLDTC
               . . | .|.|..        . . . ...  ..| . .||||  |.| ...||  
...............sladYilRelsvskk.....kkkkeerev..fqyhfksWPdhgvpkdpgavLdfl
subfamily_PTPRB_pd Subfamily PTPRB 1023-1194 3.4e-06 21.3 In-house 114-207 (293) alignment 
Range on Protein: 1023-1194
Range on HMM: 114-207/293.0
ILQQYFQKIVMLTNFTEANRQKCAVYFPIElneifavaakcevfqlsaaardyfdryltptfvpdtvvassdaidyeisgrhigvesvkvtlegdlleAL
....  . |||||.  |  ..||  |.| .                                                                      
vwekkssiivmltqlvekgkvkCeeYWPad....................................................................ee

P-AQGSfFLIKNVGIVRRNGYSVRKLVLLYcirvpqsasyHLQKIYCYHYWYPDWPDHHSPRDINTLLDTCLH
| . |.   .. |   . . . .|.| .            . ..    .| .  ||||  | . .|||| . .
pvlyGd.ikvtlvaeeeledwvirelkiek..........ekeerkvrqyhftsWpdhgvPektktlldfvrt
subfamily_PTPRD_pd Subfamily PTPRD 1024-1266 5.6e-15 50.0 In-house 112-244 (564) alignment 
Range on Protein: 1024-1266
Range on HMM: 112-244/564.0
LQQYFQKIVMLTNFTEANRQKCAVYFPIElNeiFavaAKCEVFQLSAAARDYFDRYLTPTFVPDTVVassdaidyeisgrhigvesvkvtlegdllealp
 .|  . |||||.  | ...||. |.| . .      .... .. .  .   .  |   ||   .                                   
weqnsstiVmltkleEkgkvkchkYWPek.g..t...etygeltVtleeeeeladyeirtfklkkkk.................................

aqgsffliknvgivrrngysvrklvllycirvpqsasyHLQKIYCYHYWYPDWPDHHSPRDINTLLDTCLHVLNLGKcesefdiyddtrsernahlaaqr
                                      . ..    .. . .||||  |   ..|||   .| .| .                       
......................................ssesreVrqFhFtsWPdhgvpesatslLdlirkvralne.......................

leiyqqdifNAVQPLpVIHCSAGIGRTGCFTAILNAVRQLRQS
         .  .|. |.|||||.||||.| .|   .......
.........pdagPi.vVhCSaGVGRTGtfividamlerikee
0047943 (Phosphotyrosine protein) phosphatases II 1128-1368 2e-25 85.2 In-house 136-272 (273) alignment 
Range on Protein: 1128-1368
Range on HMM: 136-272/273.0
FFLIKNVGIVRRNGYSVRKLVLLYCIrvpqsasyHLQKIYCYHYWYPDWPDHHSPRDINTLLDTCLHVLNLGKcesefdiyddtrsernahlaaqrleiy
 | ......  ...| ||.| | ..           .. ...|..|..||||. | ... ||. . .| .  .                           
kftvtllseetkddytvrtleltnlg........tgesrtvthfhytgwpdhgvppslesllefielvrkale...........................

qqdiF---NavqPLPVIHCSAGIGRTGCFTAILNAVRQLRQslaysltgmltksltsssteeyhnptdsdssftcntirhishildhrdaeavktppsfd
        |   .  |.|||||.||||.| |.. ...||.                                                            
....alpsn...gpvvVHCsaGvgRtgtfialdllldqlek...........................................................

rlpkmpDIFVDVLGIVCNLRLQRGGMVQNSEQYELIHRAICLYL
         |||| .|. || || ||||. |||.....|.. ||
......eggvdvleavkllrsqRpgmvqtpeqyrflyealleyl
0050432 (Phosphotyrosine protein) phosphatases II 1129-1371 1.5e-27 92.2 In-house 168-302 (308) alignment 
Range on Protein: 1129-1371
Range on HMM: 168-302/308.0
FLIKNVGIVRRNGYSVRKLVLLYCIrvpqsasyHLQKIYCYHYWYPDWPDHHSPRDINTLLDTCLHVLNLGkcESefdiyddtrsernahlaaqrleiyq
| .... .  ...| ||.| | ..           . ....|..|..||||. | ... ||| . .| .    ..                         
ftvtllseevlddytvrtleltnlg........dgesrtvthfhytnWpdhgvPpspeilldflelvrksl..pg.........................

qdifnavqPLPVIHCSAGIGRTGCFTAILNAVRQLRQslaysltgmltksltsssteeyhnptdsdssftcntirhishildhrdaeavktppsfdrlpk
        .  |.|||||.||||.| |.. ...||..                                                               
........gpivVHCsaGvGRtGtfialdllleqlek...............................................................

mpDIFVDVLGIVCNLRLQRGGMVQNSEQYELIHRAICLYLKRT
  .  |||...|. || || ||||. |||....||.. |||. 
..eggvdvfeavkklReqRpgmvqtpeqylflyralleylklk
0051299 (Phosphotyrosine protein) phosphatases II 1129-1369 1.4e-26 89.0 In-house 149-287 (288) alignment 
Range on Protein: 1129-1369
Range on HMM: 149-287/288.0
FLIKNVGIVRRNGYSVRKLVLLYC--IRvpqsasYHLQKIYCYHYWYPDWPDHHSPRDINTLLDTCLHVLnlgkcesefdiyddtrsernahlaaqrlei
. .... ..  ..| ||.| . ..  ..      .. ......|..|..||||. | ... ||| . .|                               
itvtllseevlddytvrtlevtnldlld......gdgesrtvthfhytnwpdhgvpdspellldflrlvr..............................

yqqD--IfnAVQPLPVIHCSAGIGRTGCFTAILNAVRQLRqslaysltgmltksltsssteeyhnptdsdssftcntirhishildhrdaeavktppsfd
   .     . ..  |.|||||.||||.| |.. ...||.                                                            
...kala..sgggpvvVHCsaGvgRtgtfialdllleqle............................................................

rlpkmPDIFVDVLGIVCNLRLQRGGMVQNSEQYELIHRAICLYLK
         ||||..|. || || ||||. |||.....|.. |||
.....keggvdvleavkrlreqRpgmvqtpeqyrfvyealleylk
0046845 (Phosphotyrosine protein) phosphatases II 1129-1372 7.7e-26 86.5 In-house 135-278 (284) alignment 
Range on Protein: 1129-1372
Range on HMM: 135-278/284.0
FLIKNVGIVRRNGYSVRKLVLLYCirvpqsaSYHLQKIYCYHYWYPDWPDHHSPRDINTLLDTCLHVLNLGKC---Esefdiyddtrsernahlaaqrle
| .... .  ...| ||.| | ..       .|  . ....|..|..||||. | ... ||. .  | .| .    .                       
ftvtllseevkddytvrtleltnl.......gytgesrtvthfhytswpdhgvppspedlleflrlvrellenlpgg.......................

iyqqdifnavqPLPVIHCSAGIGRTGCFTAILNAVRQLRQSlaysltgmltksltsssteeyhnptdsdssftcntirhishildhrdaeavktppsfdr
           .  |.|||||.||||.| |.  . .||..                                                            
...........gpivVHCsaGvgRtGtfialdllleqleke...........................................................

lpkmpD--IFVDVLGIVCNLRLQRGGMVQNSEQYELIHRAICLYLKRTL
     .  . ||||..|. || || ||||. |||.....|.. |||..|
.....glllgvdvleavkrlreqRpgmvqtleqyrfvyealleylklkl
0039614 (Phosphotyrosine protein) phosphatases II 1129-1371 1.5e-24 82.4 In-house 156-292 (297) alignment 
Range on Protein: 1129-1371
Range on HMM: 156-292/297.0
FLIKNVGIVRRNGYSVRKLVLLYcirvpQSASyhlqkIYCYHYWYPDWPDHHSPRDINTLLDTCLHVLNLGKCesefdiyddtrsernahlaaqrleiyq
| ......  ..|| ||.| . .      . |      ...|..|..||||. | ....||. .  | .  .                            
ftvtllkvehldgytvrtlevtn.....nges.....rtvthfqytgwpdhgvppslellleflelvrealae...........................

qdifNAVQPLPVIHCSAGIGRTGCFTAILNAVRQLRqslaysltgmltksltsssteeyhnptdsdssftcntirhishildhrdaeavktppsfdrlpk
    .  .   ..|||||.||||.| |.. ...||.                                                                
....lpkggpvlVHCsaGvgRtGtfiaaylmleqle................................................................

mPDIFVDVLGIVCNLRLQRGGMVQNSEQYELIHRAICLYLKRT
     |||| .|. || ||.|.||. .||. ...|.. .|||.
.keggvdvleavkelreqRpgavqtpsqyrflydallellkrk
0036941 (Phosphotyrosine protein) phosphatases II 1129-1371 1.7e-24 82.1 In-house 137-280 (297) alignment 
Range on Protein: 1129-1371
Range on HMM: 137-280/297.0
FLIKNVGIVR--RNGYSVRKLVLLYCirvpqS-AsyhlQKIYCYHYWYPDWPDHHSPRDINTLLDTCLHVLNLGKCEsefdiyddtrsernahlaaqrle
| ......     ..| .|.| ...             .. ...|..|..||||. | ....||| .  |..  |                         
ftvtllsvevvllddytlrtlevtdt.....gng....esrtvthfhytgwpdhgvpespaslldfielvrkvlkll.......................

iyqqdifnAVQPLPVIHCSAGIGRTGCFTAILNAVRQLR---QSLAYSltgmltksltsssteeyhnptdsdssftcntirhishildhrdaeavktpps
          ..  ..|||||.||.|.| |.  ...||.       ..                                                    
........psggpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvd....................................................

fdrlpkmpdifvdVLGIVCNLRLQRGGMVQNSEQYELIHRAICLYLKRT
             .| .|. || || |.||. |||. ...|.  .||..
.............ileavkklReqRpgavqtleqyrflyeallellkkk
0043336 (Phosphotyrosine protein) phosphatases II 1129-1368 8e-24 80.0 In-house 144-277 (278) alignment 
Range on Protein: 1129-1368
Range on HMM: 144-277/278.0
FLIKNVGIVRRNGYSVRKLVLLYcirvpqsaSYHLQKIYCYHYWYPDWPDHHSPRDINTLLDTCLHVLNLGkcesefdiyddtrsernahlaaqrleiyq
| ......   ..| ||.| . .         .. .. ...||.|..||||. | ....||| .  |..                               
ftvtllkeehlddytvrtlevtn........lgdgesrtvthyhylgwpdhgvpeslsllldflkavreal.............................

qdifNAVQPLPVIHCSAGIGRTGCFTAILNAVRQLRQslaysltgmltksltsssteeyhnptdsdssftcntirhishildhrdaeavktppsfdrlpk
    .  .   ..|||||.||||.| |.. ...||.                                                                
....edsngpvlVHCsaGvgRTGtfialyllleqlek...............................................................

mpDIFVDVLGIVCNLRLQRGGMVQNSEQYELIHRAICLYL
    .||.. .|. || ||.|.||. .||. ...|.. ||
..eggvdleeavkelreqRpgavqtpsqyrflyealleyl
0045450 (Phosphotyrosine protein) phosphatases II 1129-1369 9.9e-24 80.0 In-house 165-305 (307) alignment 
Range on Protein: 1129-1369
Range on HMM: 165-305/307.0
FLIKNVGIVRRNGYSVRKLVLLYCirvpqsaSYHLQKIYCYHYWYPDWPDHHSPRDINTLLDTCLHVLNLGKCesefdiyddtrsernahlaaqrleiyq
| ......   .|| ||.| . ..       ..  . ....|..|..||||. | ....||| .  |..  .                            
ftvtllseehldgytvrtlevtdl.......dgtgesrtvthfhytgwpdhgvppsfeelldfieevrkalee...........................

qdifNAVQPLPVIHCSAGIGRTGCFTAILNAVRQLRQSlaysltgmltksltsssteeyhnptdsdssftcntirhishildhrdaeavktppsfdrlpk
    .  .   ..|||||.||||.| |.. . |||..                                                               
....lpkggpvlVHCsaGvgRtGtfiaaylmlrqleke..............................................................

mpdIF---VDVLGIVCNLRLQRGGMVQNSEQYELIHRAICLYLK
        ||.| .|. || ||.|.||| |||. ...|.. .|.
...gtlldvdlleavkllreqRpgavqnpeqyrflyeallelll
0042113 (Phosphotyrosine protein) phosphatases II 1129-1369 1.1e-22 76.1 In-house 109-244 (245) alignment 
Range on Protein: 1129-1369
Range on HMM: 109-244/245.0
FLIKNVGIVRRNGYSVRKLVLLYCirvpqsasYHLQKIYCYHYWYPDWPDHHSPRDINTLLDTCLHVLnlgkcesefdiyddtrsernahlaaqrleiyq
| ......   ..| ||.| . .         .. ..  ..||.| .||||. | ....||| .  |.                                
ftvtllseehlddytvrtlevtnl........gddesrevihyhylpwpdhgvpdllellldflefvr................................

Q---DifnAVQPLPVIHCSAGIGRTGCFTAILNAVRQLRQslaysltgmltksltsssteeyhnptdsdssftcntirhishildhrdaeavktppsfdr
.   .     .   ..|||||.||||.| |.. ...||.                                                             
kalae...dsngpvlVHCsaGvgRtGtfiaaylmleqlek............................................................

lpkmpDIFVDVLGIVCNLRLQRGGMVQNSEQYELIHRAICLYLK
        |..  .|  || ||.|.||. .||. ...|.. .||
.....elgvsleeavkelrsqRpgavqtpsqyrflyeallellk
0040439 (Phosphotyrosine protein) phosphatases II 1129-1370 3.4e-22 74.7 In-house 111-248 (249) alignment 
Range on Protein: 1129-1370
Range on HMM: 111-248/249.0
FLIKNVGIVRRNGYSVRKLVLLYCirvpqsasYHLQKIYCYHYWYPDWPDHHSPRDINTLLDTCLHVLnlgkcesefdiyddtrsernahlaaqrleiyq
| .... .   ..| ||.| | .         |. ......|..|.|||||. | ....||| .  |.                                
ftvtllsvevkddytvrtleltnl........ydgesrtvlhiqytdwpdhgvppsfedlldfieavr................................

qD----IfnAVQPLPVIHCSAGIGRTGCFTAILNAVRQLRQslaysltgmltksltsssteeyhnptdsdssftcntirhishildhrdaeavktppsfd
 .    .    .   ..|||||.||||.| |.. ...||.                                                            
.kaleel..pkggpvlVHCsaGvgRtGtfiaaylmleqlek...........................................................

rlpkmpDIFVDVLGIVCNLRLQRGGMVQNSEQYELIHRAICLYLKR
         ||.. .|. || ||.|.||| |||. ...|.. .|..
......elgvdleeavkllrsqRpgavqnpeqyrflyeallelllk
0045098 (Phosphotyrosine protein) phosphatases II 1129-1370 1.5e-17 59.3 In-house 121-274 (278) alignment 
Range on Protein: 1129-1370
Range on HMM: 121-274/278.0
FLIKNVGIVRRNGYSVRKLVLLYCIRVPqsasYHLQKIYCYHYWYPDWPDHHSPRDI--NTLLDTCLHVLNLGKCESE-----Fdiyddtrsernahlaa
| .... . . . | .|.| . ..   .    ..|.. . .|..|. ||||..| .   . .|. .  ...  |   .     .                
ftvtllseevlddytlrtllvtnltver....edlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllssl................

qrleiyqqdIFNAVQPLPVIHCSAGIGRTGCFTAILNAVRqlrqslaysltgmltksltsssteeyhnptdsdssftcntirhishildhrdaeavktpp
         ...  .   ..|||||.||||.. |.    .                                                            
.........llldsggpvlVHCsaGvgRtGtlvaaylmle............................................................

sfdrlpkmpdI---FVDVLGIVCNLRLQRGG-MVQNSEQYELIHRAICLYLKR
               ||.| .|. || ||.| .||| |||. ........|.|
..........lleggvdlleavkelrsqRpglavqnleqyrflyefllelllr
Y_phosphatase Protein-tyrosine phosphatase 1159-1266 4.6e-12 41.2 Pfam-A 127-200 (235) alignment 
Range on Protein: 1159-1266
Range on HMM: 127-200/235.0
ASYHLQKIYcYHYWYPDWPDHHSPRDINTLLDTCLHVLNLGkcesefdiyddtrsernahlaaqrleiyqqdifNAVQPLPVIHCSAGIGRTGCFTAILN
.. . ...  ....| .||||  |.. . |||..  | .                                   .| .   |.|||||.||||.| |.  
keesekrev.kqlhytnWpdhgvpespkslldlirkveksk.................................eaksgpvvVhCsaGvgRtgtfvaldi

AVRQLRQS
...||.. 
lleqleae
Y_phosphatase Protein-tyrosine phosphatase 1159-1266 4.6e-12 41.2 In-house 127-200 (235) alignment 
Range on Protein: 1159-1266
Range on HMM: 127-200/235.0
ASYHLQKIYcYHYWYPDWPDHHSPRDINTLLDTCLHVLNLGkcesefdiyddtrsernahlaaqrleiyqqdifNAVQPLPVIHCSAGIGRTGCFTAILN
.. . ...  ....| .||||  |.. . |||..  | .                                   .| .   |.|||||.||||.| |.  
keesekrev.kqlhytnWpdhgvpespkslldlirkveksk.................................eaksgpvvVhCsaGvgRtgtfvaldi

AVRQLRQS
...||.. 
lleqleae
0048179 (Phosphotyrosine protein) phosphatases II 1162-1257 1.9e-08 29.7 In-house 43-104 (144) alignment 
Range on Protein: 1162-1257
Range on HMM: 43-104/144.0
HLQKIYCYHYWYPDWPDHHSPRDINTLLDTCLHVLNLgkcesefdiyddtrsernahlaaqrleiyqqdifNAVQPLPVIHCSAGIGRTGCFTAIL
.  . . ..|.. .||||. | ... ||...  . ..                                   .     ..|||||.||||.. |. 
efleregiqylhlpwpDhgvpdllellleflefieea..................................leeggpvlVHCsaGvgRtgtlvaay
0048076 (Phosphotyrosine protein) phosphatases II 1165-1258 1.5e-09 33.2 In-house 44-103 (145) alignment 
Range on Protein: 1165-1258
Range on HMM: 44-103/145.0
KIYCYHYWYPDWPDHHSPRDINTLLDTCLHVlnlgkcesefdiyddtrserN----AhlaaqrleiyqqdifnavQPLPVIHCSAGIGRTGCFTAILN
. . ..|.| .||||. | ....||. .  .                    .    .                      ..|||||.||||.. |.  
erlgiqylylpwpDhgvpdllellleflefi....................eealke..................ggpvlVHCsaGvgRtgtlvaayl
PTPc_DSPc_SM00012 1168-1364 1.1e-21 72.4 In-house 2-103 (105) alignment 
Range on Protein: 1168-1364
Range on HMM: 2-103/105.0
CYHYWYPDWPDHHSPRDINTLLDTCLHVLNLGKCESEfdiyddtrsernahlaaqrleiyqqdifnavQPLPVIHCSAGIGRTGCFTAILNAVRQLRQSL
..||.|..||||. |.. . .|... .| .  . ...                               ..  |.|||||.||||.|.|.  ...||... 
vkhyhytgwpdhgvPeesdsilellravkknknkses...............................skpvvVhCsaGvgRtgtfvaldillqqleket

aysltgmltksltsssteeyhnptdsdssftcntirhishildhrdaeavktppsfdrlpkmpdIFVDVLGIVCNLRLQRGGMVQNSEQYELIHRAI
                                                                 .||.. ||. || || ||||. |||  ..||.
................................................................kevdifqivkelrkqRpgmvqteeqylflyral
subfamily_PTPN3_pd Subfamily PTPN3 1168-1262 1.1e-08 29.4 In-house 173-234 (280) alignment 
Range on Protein: 1168-1262
Range on HMM: 173-234/280.0
CYHYWYPDWPDHHSPRDINTLLDTCLHVLNLGkcesefdiyddtrsernahlaaqrleiyqqdifnAVQPLP-VIHCSAGIGRTGCFTAILNAVRQ
  .  | .||||  | | . .|.   .| .|                                   ...  | |.|||||||||| . ..  |.  
ilqlqylaWpdhgvPddsadflefvervrklr..................................sgkeePvvvhCsaGigrtGvlilletalal
subfamily_PTPN9_pd Subfamily PTPN9 1169-1266 8.5e-08 26.6 In-house 176-253 (297) alignment 
Range on Protein: 1169-1266
Range on HMM: 176-253/297.0
YHYWYPDWPDHHSPRDINTLLDtclhVLnlgkcesefdiyDDTRSERnahlAAQRLEIYQQDIFNAVQPLPVIHCSAGIGRTGCFTAILNAVRQLRQS
 |. .  |||.  |.. ..|||    ||            .  |...    |.   |. ... ... .|  |.|||||||||| |...  .. .|.. 
thfqflsWPdyGvPssaaslld....vl............ekvrekq....alavkelgdewkghpsgPPivvhcsaGiGrtGtfitldiclsrleev
subfamily_PTPN23_pd Subfamily PTPN23 1173-1372 1.2e-09 32.5 In-house 178-284 (288) alignment 
Range on Protein: 1173-1372
Range on HMM: 178-284/288.0
YPDWPDHHSPRDINTLLDTCLHVLN-LGKCESEFDIyddtrsernahlaaqrleiyqqdifnavqPLpVIHCSAGIGRTGCFTAILNAVRQLRQSLAYSl
.  ||..  |   .|||.    | . . . . . ..                             || |.|||||.|||| |. .  |||.|..      
ltsWpelGvPasPetllqfldevesayeavqrkskt.............................Pl.vvhCsaGvgRtgvfalvyaavrelekgngll.

tgmltksltsssteeyhnptdsdssftcntirhishildhrdaeavktppsfdrlpkmpdifvDVLGIVCNLRLQRGGMVQNSEQYELIHRAICLYLKRT
                                                               |.. .|  || ||  |||..||..    |.  . .|.
...............................................................diiqvvsrlreqRrfmvqekeqlkfsyeavleaarrv

L
|
l
subfamily_Choan-PTP-1_pd Subfamily Choan-PTP-1 1222-1266 7.1e-08 26.9 In-house 195-238 (281) alignment 
Range on Protein: 1222-1266
Range on HMM: 195-238/281.0
QRLEIYQQDIFNAVQPLpVIHCSAGIGRTGCFTAILNAVRQLRQS
 | |... .  .  .|| |||||||.||||.. |.  .|... ..
frkevlkltekktkapl.vihCsaGvGrtGtyialDrlvkaveae
subfamily_Choan-PTP-2_pd Subfamily Choan-PTP-2 1237-1266 3.2e-06 21.3 In-house 199-227 (270) alignment 
Range on Protein: 1237-1266
Range on HMM: 199-227/270.0
PLpVIHCSAGIGRTGCFTAILNAVRQLRQS
|| ..|||||.||||.. |.  ||| | ..
Pl.lvHcsaGvgRtGtlialDiavrlLeet
subfamily_Cele-PTP-20_pd Subfamily Cele-PTP-20 1237-1274 3.5e-06 20.9 In-house 218-254 (290) alignment 
Range on Protein: 1237-1274
Range on HMM: 218-254/290.0
PLpVIHCSAGIGRTGCFTAILNAVRQLRQSLAYSLTGM
|. |.|||||||||| |.||  ... | .  .. | ..
pv.vvhcsaGiGrtGtfvaievglqilldGkeldlldl
subfamily_PTPRB_pd Subfamily PTPRB 1239-1268 3.1e-06 21.4 In-house 221-250 (293) alignment 
Range on Protein: 1239-1268
Range on HMM: 221-250/293.0
PVIHCSAGIGRTGCFTAILNAVRQLRQSLA
 |.|||||.|||| | |. . .......  
ivvhCsaGvGRtGtfialdrllqaieeedy
subfamily_PTPRB_pd Subfamily PTPRB 1333-1370 1.3e-07 26.0 In-house 250-287 (293) alignment 
Range on Protein: 1333-1370
Range on HMM: 250-287/293.0
FVDVLGIVCNLRLQRGGMVQNSEQYELIHRAICLYLKR
.||..|||..|| .|  .||. .||  ||...  .|..
yvdifgivaelReeRnllvqtekqYifihqcvldllrk
subfamily_PTPRD_pd Subfamily PTPRD 1333-1369 1.3e-07 25.7 In-house 246-282 (564) alignment 
Range on Protein: 1333-1369
Range on HMM: 246-282/564.0
FVDVLGIVCNLRLQRGGMVQNSEQYELIHRAICLYLK
 ||. ..| .|| ||  |||. |||  ||.||  .|.
tvDiyqyvkalrkqRnamVqteeQYiFiheaileala
subfamily_Anemone-PTP-5_pd Subfamily Anemone-PTP-5 1333-1369 1.9e-07 25.5 In-house 248-284 (319) alignment 
Range on Protein: 1333-1369
Range on HMM: 248-284/319.0
FVDVLGIVCNLRLQRGGMVQNSEQYELIHRAICLYLK
 .||  .| .||.||  |||. |||..|. |.  ...
vlDvfstvsrlRtqRnimvqrpeqYkfiyealleave
subfamily_Urchin-PTPRB-like_pd Subfamily Urchin-PTPRB-like 1333-1365 7.2e-07 23.5 In-house 244-276 (288) alignment 
Range on Protein: 1333-1365
Range on HMM: 244-276/288.0
FVDVLGIVCNLRLQRGGMVQNSEQYELIHRAIC
..||.|.|..|| ||  .||. .||| |.... 
yiDvagtvaklRkqRallvqtlkqYefiyevll
subfamily_Anemone-PTP-6_pd Subfamily Anemone-PTP-6 1333-1369 7.8e-07 23.4 In-house 245-281 (318) alignment 
Range on Protein: 1333-1369
Range on HMM: 245-281/318.0
FVDVLGIVCNLRLQRGGMVQNSEQYELIHRAICLYLK
 |||...| .|| ||  |||  .|||.|. ..  .|.
lvDvfqtvkqlreqrnlmvqtedqyefiydvlleala
subfamily_Sponge-PTP5_pd Subfamily Sponge-PTP5 1333-1364 6.5e-06 20.2 In-house 231-262 (283) alignment 
Range on Protein: 1333-1364
Range on HMM: 231-262/283.0
FVDVLGIVCNLRLQRGGMVQNSEQYELIHRAI
 |||  .| ..| || ..||. .|| |.| ..
vvdvfavvkimreqrmmavqtldqyklvhelv
subfamily_PTPN12_pd Subfamily PTPN12 1334-1373 5.7e-08 27.0 In-house 243-282 (290) alignment 
Range on Protein: 1334-1373
Range on HMM: 243-282/290.0
VDVLGIVCNLRLQRGGMVQNSEQYELIHRAICLYLKRTLA
.||  .| .|| ||  .||  |||||...|.  .....|.
ldvfdlvlelrkqraalvqtkeqyelvykavaelvqkele
Y_phosphatase Protein-tyrosine phosphatase 1334-1364 5.1e-07 24.7 Pfam-A 203-233 (235) alignment 
Range on Protein: 1334-1364
Range on HMM: 203-233/235.0
VDVLGIVCNLRLQRGGMVQNSEQYELIHRAI
|||| ||..|| || ||||. |||. ...||
vdvlqivkelRkqRpgmvqsleqYiflykai
Y_phosphatase Protein-tyrosine phosphatase 1334-1364 5.1e-07 24.7 In-house 203-233 (235) alignment 
Range on Protein: 1334-1364
Range on HMM: 203-233/235.0
VDVLGIVCNLRLQRGGMVQNSEQYELIHRAI
|||| ||..|| || ||||. |||. ...||
vdvlqivkelRkqRpgmvqsleqYiflykai
subfamily_Ptp69D_pd Subfamily Ptp69D 1334-1369 2.2e-06 22.0 In-house 252-287 (307) alignment 
Range on Protein: 1334-1369
Range on HMM: 252-287/307.0
VDVLGIVCNLRLQRGGMVQNSEQYELIHRAICLYLK
||.  .|..|| ||  .||. |||. ..||.  | .
vdifetvkdLrsqRnllvqsleqYvflyralldyss
subfamily_Choan-PTP-2_pd Subfamily Choan-PTP-2 1334-1371 3.8e-06 21.1 In-house 230-267 (270) alignment 
Range on Protein: 1334-1371
Range on HMM: 230-267/270.0
VDVLGIVCNLRLQRGGMVQNSEQYELIHRAICLYLKRT
|||| |. .|| .|  .|| .||||....|. .| .|.
vdvlaiieelRkdRmalvqhpeqyeflykavveyaerr