CRAL_TRIO |
CRAL/TRIO domain |
167-314 |
4.3e-30 |
93.0 |
Pfam-A |
3-159 (159) |
alignment |
Range on Protein: 167-314
Range on HMM: 3-159/159.0
LQTGKFTILPARTSSGAAIALFTANRHSPLSVSHTTTLQGIVYQLDSALQDSET--QRAGLVFIYDMSGSKYSNFD---YDLSQKILTLLKGGYPARLKK
...|...... | . | . .. ..|. | ..|. . .. ....|...|.. |. |..|.....||.| ..|... ..| .|||..|. || ||.|
ileggkvgihgrDkngrpvlylrlgrfdpkklseeelvrllllvlerllklleedgqiegvtvviDmkglslskmlwkpisllkkilkilqdnyperlgk
VLIVTAPLWFKAPFKILRLFVREKLRERVFTVSVP----QLALHVPRKALPIHLGGT
.||| || .||. ||... |. ||.||... || .| ..... || ||||
ilivnaPklfkvafklvkpfldektreKikfvspsntpatlekyidpeqlpkelGGt
|
CRAL_TRIO_2 |
Divergent CRAL/TRIO domain |
177-319 |
2.8e-14 |
42.0 |
Pfam-A |
8-148 (149) |
alignment |
Range on Protein: 177-319
Range on HMM: 8-148/149.0
ARTSSGAAIALFTANRHSPLSvSHTTTLQGIVYQLDSALQDSEtqragLVFIYDMSG-SKYSNFDYDLSQKILTLLKGGYPARLKKVLIVTAPLWFKAPF
. ..| . .| |.. ... .. .|. .. | ..... | .|...| |. ..... . |.. .| |. .||||..| . ..| .
gkdregrpvvvfiakylpstd.dydkllkyllhtledeivgkp.....yvlVyfhtglssenkpslswlkklyktlprrykknlkkvylvhpstflksil
-KILRLFVREKL-RER-VFTVSVPQLALHVPRKALPIHLGGTLEVDH
.|.|||..| . .. |. .|. .. .. |...|.|... |.
stllslfvskkflkkkviyisslseLseyiditqlkkslpgvysyde
|
subfamily_Urchin-PTP-5_pd |
Subfamily Urchin-PTP-5 |
511-808 |
9.1e-62 |
203.9 |
In-house |
5-287 (297) |
alignment |
Range on Protein: 511-808
Range on HMM: 5-287/297.0
QEGDPKPIDQIVQMVkQRGRHGLI-KEYADIRNRAPEGTFLHARMRANLTKNRYTDVLCYDHSRVVLAHEDGDEPSDYINANFVDGYKQknAYISTQGPL
.| | |. .. .| |..|| . .| .| . |. . |. |.||...| || ||| || . | |||.|| || |.|. .|.|| |
kerrpiplsdfatlv.qknrhtdvfseeflclpeaniqpqtvaekkvnfeksRYkniLPydssRvkLaivnddpdsDyvnasfvkgnkh..rlittqmPm
PKTSQDFWRMIWEQHCLVIVMTTRVMERGRvKCGQYWepTEESSLEFGDYHVRTISVECNEDYMVASLELRNIKTDEIRNVSHWQFTSWPDYGVPS--SA
. | .|||.|..... .||| . || . || .|| ..... .||| | . ||. | .. .||... |. | | .||..||| |. ||
katvadfWamvldeqvstivmlnddnerdk.kcaryW..sdkgvttfGdvsvvllsvsereGfikrelevtkgkakarrvvkqyqfveWPdkaverkdsa
MAMLNFLQKVREKQAQlvqglgdtwagHPRGpPIVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEYAYS
..|.... ||.. | . | |..|||.||.|||| ..|.| .... .. . || |.|.|.| .| | .| .|| | . |..|. .|
ssllklisevrkdfsq...........naeg.PllvhclaGvGrtgvlltidsvvaeakrekevdifglvkklrqerpylvqtkeqykfvyvavlealls
R
e
|
0045450 |
(Phosphotyrosine protein) phosphatases II |
514-805 |
4.9e-96 |
317.3 |
In-house |
10-304 (307) |
alignment |
Range on Protein: 514-805
Range on HMM: 10-304/307.0
DPKPIDQIVQMVKQRGRHGLIKEYADIRNRAP--EGTFLHARMRANLTKNRYTDVLCYDHSRVVLAHEDGD-EPSDYINANFV--------DGYKQKNAY
|.......|.. .. ...|| ||. .... . |.. .|.. .| .||||.|.|.|||.||.| ..||. |.||||||..| |||..|...
dalkllllvllllldfltgllkefekllsvtvfllgeysiallpenkdknrykdilpydhtRVklssldgsledsdYiNAsyvrvpllllldgydlkrkf
ISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERGRVKCGQYWePTEESSLEFGDYHVRTISVECNEDYMVASLELRNI-KTDEIRNVSHWQFTSWPDY
| ||||||.| |||||.|||.. |||| |. .|.||.|| ||| |.|...|..|...|...|.| ..| | ||. . .|.| | | |...|.|||.
IatqgPlpetvedFwrmlweqgvtvivmltelvelgrekcaqyw.Pdegeeltygnftvtllseehldgytvrtlevtdldgtgesrtvthfhytgwpdh
GVPSSAMAMLNFLQKVREKQAQlvqglgdtwagHPRGPPIVVHCSAGIGRTGTFITLDICISRLEDVGT---ADIRGTVEKIRSQRAYSIQMPDQYVFCH
|||.| .|.|...||. ... .|.| |..||||||.|||||||........||. || |.. .|...|.|| ..| |.||.|..
gvppsfeelldfieevrkalee...........lpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrfly
LALIEYA
||.|.
eallell
|
subfamily_Urchin-PTP-7_pd |
Subfamily Urchin-PTP-7 |
514-804 |
2e-66 |
219.1 |
In-house |
4-278 (315) |
alignment |
Range on Protein: 514-804
Range on HMM: 4-278/315.0
DPKPIDQIVQMVKQR---GRHGLIKEYADIRNRAPeGTFLHARMRANLTKNRYTDVLCYDHSRVVLAHEDGDEPSDYINANFVDGYKQKNAYISTQGPLP
.| |.||.. | |. . |. ..| | . |. | |||| ... ||.||| | . |. |||.||||.|||..|. ||..|||..
qpipldqlityvaqkkastkngfkqdyesipggql.hpldvakkienkqknryiniiaydksrvqlpllendphsdyvnanfidGynkkrryiaaqgpnv
KTSQDFWRMIWEQHCLVIVMTTRVMERGRVKCGQYWePTEesSLEFGDYHVRTISVECNEDYMVASLelRNIKTDEIRNVSHWQFTSWPDYGVPSSAMAM
. .||||...|... ||| | ..|. . |. .|| | . . .| . | .| | |..| | .| . |.||.| ...||||| ||| .....
asvkdfwrlvfeedigkivmltnlvegekrkaekyw.pdk..kviyGkitvtrkseevnteytvrtl..svvfgdnirevvqlhytswpdmgvpkytipl
LNFLQKVREKQAQLVqglgdtwaghprgPPIVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEY
.|. ..|. . . | .||||||||.|||||||||| . ..| |. ....|..| .|. .|| | . ||.|
mnlirtvkqhhtnsv.............gaivvhcsaGvGrtGtfitldavldqaeaenaidvynfitgvrqnrikmvqvaeqyqfiydallet
|
0040438 |
(Phosphotyrosine protein) phosphatases II |
515-809 |
3.6e-101 |
333.9 |
In-house |
2-280 (317) |
alignment |
Range on Protein: 515-809
Range on HMM: 2-280/317.0
PKPIDQIVQMVKQRGRHGLIKEYADIRNRAPEgTFLHARMRANLTKNRYTDVLCYDHSRVVLAHEDGDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQ
...... .. ..... ..| .|. |... .. |. .|.. .| ||||.|.|.||||||.| ...||..||||||..|||...|...| ||||||.|
vldlllalldllksdftalleefedllslkld.tysvaelpenkdknrypdilpydhsRVkLsplggdldsdYInAsyvdgpnlkrkfIatqgPlpntve
DFWRMIWEQHCLVIVMTTRVMERGRVKCGQYWEPteESSLEFGDYHVRTISVECNEDYMVASLELRNIKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFL
|||||.|||.. |||| |. .|.||.|| ||| ...|..||..|...|.| .... . ||. . ...| | | |...|.|||.|||.| .|.||
dFwrmvweqgvtvivmLteleelgrekcaqYwpl..getltygdftvtllseeelagitlrtlevedlgdsesrtvthfhytgWpdhgvppspdllldfl
QKVREKQaqlvqglgdtwagHPRGPPIVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEYAYSRG
..|||.. ..| |..||||||.|||||||........|| |. |. .|...|.||....|.|.||.|.. ||.|| . ..
eavreal.............edpggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrflydalleylkrkl
|
subfamily_PTPRA_pd |
Subfamily PTPRA |
515-810 |
8.7e-79 |
259.8 |
In-house |
13-301 (330) |
alignment |
Range on Protein: 515-810
Range on HMM: 13-301/330.0
PKPIDQIVQMVKQRGRHGlIKEYADIRNRAPE----GTFLHARMRANLTKNRYTDVLCYDHSRVVLAHEDGDEPSDYINANFVDGYKQKNAYISTQGPLP
| |.... . ...| | . . | | .|. | | |||. ..| ||.|||.|.. .| | |||||| |.||||.|. .|..|||.
plpvekleeeirirsadd.nklfreefnalPagpiqatlelaskeenkeknrvvnilPydfsrvilsvkeGveesdyinasfidGykekdkfiaaqGPke
KTSQDFWRMIWEQHCLVIVMTTRVMERGRVKCGQYWePtEESSLEFGDYHVRTISVECNEDYMVASLELR----NIKTDEIRNVSHWQFTSWPDYGVPSS
.| .|||||||||. ||| | . || . || ||| | .| .. .|. .| .. .|| | . .. . . .. | |. . |||||| |||.
etvedfwrmiweqksativmltelkerkeekcaqyw.P.deGlvtyGnirvevedetvlvdytvrkflvqqlpdatrekksrlvrqfhftswPdvGvPfe
AMAMLNFLQKVREKQAQlvqglgdtwaghpR-GpPIVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEY-
.. ||..|.||.... | | |||||||||.|||||||.|| . |.. . |. ..|...| ||. .| ||.|.. .| ||
piGmlkllkkvkklnqq.............sag.pivvhcsaGvGrtGtfivldavlervkaerkvdvfefvkrlrlqrpqmvqtdeqyefiykvlleyy
AYSRGM
|
lygdte
|
subfamily_Urchin-PTP-1_pd |
Subfamily Urchin-PTP-1 |
515-812 |
1.7e-62 |
206.1 |
In-house |
2-284 (315) |
alignment |
Range on Protein: 515-812
Range on HMM: 2-284/315.0
PKPIDQIVQMVKQRGRH-GLIKEYADIRNRAPEGTfLHARMRANLTKNRYTDVLCYDHSRVVLAHEDGDEPSDYINANFVDGYKQKNAYISTQGPLPKTS
| |. |. .|.. . . .|. |. . . . || . | .|||| ..| .|..||.| | . |||||| .. .... .|||..||||. .
pipvaqfpafvnknrhtalfseefhdlpdPdiyrq.rvaretinfkknryknilPldsarvkleviddsPdsdyinasyiksvdddkayiasqgPlkasv
QDFWRMIWEQHCLVIVMTTRVMERGRVKCGQYWEPTEESSLEFGDYHVRTISVECNEDYMVASLELRniKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNF
.|||||..... ||| | | ..|| ||| . | ||| ..| ..|.| . | .. | .| |..| |.|. .||| ||| ||. . ..|..
ddfwrmvlqekvttivmvtkkqegdkikcrqywPdrkadsvefGsikvellsleadtdgvarklvtr..kseesrtvtqfqftewPdkGvdkqtssllkl
LQKVREKQAQlvqglgDTWaghprgpPIVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEYAYSRGMLQ
...|. .. . ... ...||||||.|||| .|..| ....... . |. .|...|..| | .| ..| | . |. |. . | |
ikevkadngk......kef.......sllvhcsaGvGrtGvvisidevvaqikrtrsvdvfnfvknlrakrpylvqteeeyafiydavledllwrntli
|
subfamily_Urchin-PTP-4_pd |
Subfamily Urchin-PTP-4 |
515-811 |
3.7e-44 |
145.7 |
In-house |
3-242 (392) |
alignment |
Range on Protein: 515-811
Range on HMM: 3-242/392.0
PKPIDQIVQMVKQRGRHG-LIKEYADIRNRAPeGTFLHARMRANLTKNRYTDVLCYDHSRVVLAHEDGDEPSDYINANFVDGYKQKNAYISTQGPLPKTS
| |. |. .|.. . ...|. |. . |. || |||| ..| || .||.| | |||.|| .........|||..||| . .
pipvaqfpafveknrhsalffeefhdlpgpdi.ypqtvaqkeinlkknryknilpydsarvkleviddipdsdylnasyipsfdnekayiasqgpnaasl
QDFWRMIWEQHCLVIVMTTRVMERGrvkcgqywepteesslefgdyhvrtisvecnedymvaslelrniKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNF
.|||||..... |.| |.. | | |. | |. ..|| ||| .|| . ..|.|
ddfwrmvfqenvttiamvtklkegd............................................kgddartvaqfhftewPdkdvpkhtssllkf
LQKVREKQAQLVqglgdtwagHprgpPIVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEYAYSRGML
...|. . | | |...|||||.|||| |..| ... . . |. | .|| .| | .| .|| | . |..| | |
ikevkadfGqyt.........h....pliihcsagvgrtgvvisidsvvahakktrmvdvfnfvtnirrkrpymvqtkeqyafiygavledllwrntl
|
subfamily_Cele-PTP-18_pd |
Subfamily Cele-PTP-18 |
516-812 |
5e-45 |
148.5 |
In-house |
7-294 (305) |
alignment |
Range on Protein: 516-812
Range on HMM: 7-294/305.0
KPIDQIVQMVKQRGRHGLIKEYADIRNRAPEGTFLHARMRANLTKNRYTDVLCYDHSRVVLaheDGDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQD
| | ..|. . ..| .|| .|.. .. . . . |||| || | |. || | .| | .|| ||.| . . .| || || || |
kqilkfvkrtlekgpaglraefvamkrfndfekmkafkeaqeagknrykdvgcldnnrvkl...egpwpheyihanyvstptnpkrfictqaplektcad
FWRMIWEQHCLVIVMTTRVMERGRVKCGQYWEPTEESSLEFGDYHvRTISVECN--EDYMVASLELRNI---------KTDEIRNVSHWQFTSWPDYGVP
|| | .... | | ..|.| || .|. .. ||| . . ||| .. . . . .. . | |.|. . ||| |||
fwymclqdkveaifmlcnllekgakkcleyfaskdkdvlefeekg.qkisvkfessvtlkfrkdakakvtetvlviegpgekarkvthyhwidwpdrgvp
SSAMAMLNFLQKVREKQaqlvqGlgdtwaghprgpPIVVHCSAGIGRTGTFITLDICISRLEDV-GTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIE
.. .|.|..|.| | . | ||||||||||||||. . |. . .| | . ||| || ||| .||.| | ...
aadlailellekarpsk.....g............pivvhcsagigrtgsvvmleyildqllagqiiedtdkilqkireqrnnsiqtdaqylfvhqviln
YAYSRGMLQ
| ...|.
yfrkkklld
|
subfamily_PTPN9_pd |
Subfamily PTPN9 |
517-810 |
6.3e-162 |
532.6 |
In-house |
2-296 (297) |
alignment |
Range on Protein: 517-810
Range on HMM: 2-296/297.0
PIDQIVQMVKQRGRHGLIKEYADIRNRAPEGTFLHARMRANLTKNRYTDVLCYDHSRVVLAHEDGDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDF
|...|..||..|..||.||||.|||...|||||....||||.|||||||||||..|||||..|.|| |||||||||||||||.|.|.|||||.||..||
eieelvayvkekgkrGlskeyaeirnepveGtflasklranleknrytdvlcydetrvvlakvdedeasdyinanfvdGykqkkafiatqGplkktvsdf
WRMIWEQHCLVIVMTTRVMERGRVKCGQYWEPTEESSLEFGDYHVRTISVECNEDYMVASLELRNIKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQK
|||.|||..|||||||||.||||.||||||...|||| ||||..|....||..|||.|..||..|.||.|.|.|.|.||.|||||||||||...|..|.|
WrmvWeqevlvivmttrvvergrlkcgqyWpleeessaefgdlsvsnveveeeedykvrvleiknvkteesrkvthfqflsWPdyGvPssaaslldvlek
VREKQAQLVQGLGDTWAGHPRGPPIVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEYA-YSRGM
||||||..|. |||.|.|||.||||||||||||||||||||||||.||||.|||.|.. ||...|.|||.|||.|.||.||.||..||| .....
vrekqalavkelgdewkghpsgPPivvhcsaGiGrtGtfitldiclsrleevgtvdvvetvkllrtqrafsiqtpeqyefcylavleyalelkal
|
subfamily_PTPN14_pd |
Subfamily PTPN14 |
517-804 |
2.6e-65 |
215.4 |
In-house |
8-295 (300) |
alignment |
Range on Protein: 517-804
Range on HMM: 8-295/300.0
PIDQIVQMVKQRGRHGL-IKEYADIRNRAPEGTFLHARMRANLTKNRYTDVLCYDHSRVVLAHEDGDePSDYINANFVDGY--KQKNAYISTQGPLPKTS
. |. ....... ..| .|| | .. .... |.. | |||. ||| |...|| |. . ..|||| . .. || .||||..|
tkdkrakilekkleegkvfteyeripkkredallstaklpenaeknrfkdvlPyednrvelsptken.stgyinassikvsvggkersyivaqgPleltv
QDFWRMIWEQHCLVIVMTTRVMERGRVKCGQYWEPT--EESSLEFGDYHVRTISVECNEDYMVASLELRNIKTDEIRNVSHWQFTSWPDYGVPSSAMAML
||||.|.|||. .||| |. | |. |. .|. . .....||| ..| | .| . .. .|.|. . . | |.| | |.| ||| |||. .|
qdfWqmvWeqgvqlivmlteeeedgkeksfkyfPkleskkktvefgkfkvttkfsedsdsvittglklkhlpskeertvwhlqytDWpdhgvPeDvkgfl
NFLQKVREkqaqLVQGLGDTWAGHPRGPPIVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEY
..|..|. . . .. .. . ||..||||||.|||| |. |. |. || . ||. .....| || . .| || | . .||.|
syLeevqs....vrrktnseveskeskPPvlvhCsaGvGrtGvlilsdlliatlehneeidikkvlarLreqrmllvqtlaqYkfvYkvliky
|
0050432 |
(Phosphotyrosine protein) phosphatases II |
518-807 |
3.6e-105 |
346.9 |
In-house |
29-301 (308) |
alignment |
Range on Protein: 518-807
Range on HMM: 29-301/308.0
IDQIVQMVKQRGRHGLIKEYADIRNRAPEGTFLHARMRANLTKNRYTDVLCYDHSRVVLahedgDEPSDYINANFVDGY--KQKNAYISTQGPLPKTSQD
.| . .. |. ....| .|. .... | ... .|.. .| .||||.|.|.||||||.| ||.||||||..|||| |.....| ||||||.| |
ldllkllekaldlglleeefeellsvkplleysvallpenkdkNrykdilpydhsRVkl.....degsdYInAsyvdgyssklprkfIatqgPlpntved
FWRMIWEQHCLVIVMTTRVMERGRVKCGQYWEPTEE-SSLEFGDYHVRTISVECNEDYMVASLELRNIKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFL
||||.|||.. |||| |. .|.||.|| ||| .... .|||.|...|...|.| ..||.| |||.|....| | | |...|.|||.|||.|. ..|.||
FwrmvweqnvrvIvmLtklvengrekcaqYwplelgggsleygkftvtllseevlddytvrtleltnlgdgesrtvthfhytnWpdhgvPpspeilldfl
QKVREKQaqlvqglgdtwaghpRGPPIVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEYAYS
..||... .|.|||||||||.|||||||.||.....|| |. |. ..| |.|.||....| |.||.|.. ||.||...
elvrksl...............pggpivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkklReqRpgmvqtpeqylflyralleylkl
|
0039614 |
(Phosphotyrosine protein) phosphatases II |
518-805 |
1.5e-94 |
312.0 |
In-house |
19-289 (297) |
alignment |
Range on Protein: 518-805
Range on HMM: 19-289/297.0
IDQIVQMVKQRGRHGLIKEYADIRNRAPEgtFLHARMRANLTKNRYTDVLCYDHSRVVLAHEDG-DEPSDYINANFVDGYKQ-KNAYISTQGPLPKTSQD
.|..... |. ....|..|. .. . |. . .|. .| .||||.|.|.||||||.| .||| |..||||||..||||.. ....| ||||||.| |
ldlllllekansktllllefeellslkpd..ysiallpenkdknrykdilpydhsrvklkpedgvdldsdYinAsyvdgydlltrkfIatqgPlpetved
FWRMIWEQHCLVIVMTTRVMERGRvKCGQYWEPTEEsslEFGDYHVRTISVECNEDYMVASLELRNikTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQ
||||.|||.. |||| |. .|.|| || ||| .... ..||..|....|| ...|.| ||..| ..| | | |.|.|.|||.|||.|. .|.||.
FwrmvweqgvtvivmLtklvelgr.kcaqywpeegg...tygdftvtllkvehldgytvrtlevtn..ngesrtvthfqytgwpdhgvppslelllefle
KVREKQAQLvqglgdtwaghPRGPPIVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEYA
.||| .|.| |.| |..||||||.|||||||........|| |. |. .|...|.|| ...|.|.||.|.. ||.|.
lvrealael...........pkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavqtpsqyrflydallell
|
subfamily_PTPRD_pd |
Subfamily PTPRD |
519-806 |
3.1e-107 |
354.6 |
In-house |
11-282 (564) |
alignment |
Range on Protein: 519-806
Range on HMM: 11-282/564.0
DQIVQMVKQRGRHGLIKEYADIRNRaPEGTFLHARMRANLTKNRYTDVLCYDHSRVVLAHEDGDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWR
. |. .|. . . .|| .|... .. |. .|.. || |||| ... |||||||| . .||| ||||||.|.|||....||| |||||..| .||||
kehvaklkansdlkfeeeykkieeg.qqftweaankpaNkaKNRyanivaYdhsRVvLskvegdegsDYINAsfidgyrkrkayIAtqgPlaetiedFWR
MIWEQHCLVIVMTTRVMERGRVKCGQYWePTEEsSLEFGDYHVRTISVECNEDYMVASLELRNIKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVR
|.|||.. .||| |.. |.|.||| .|| |... . ..|...| . | .||.. ...|.. |..| |.| ...|||||| ||| || ..|....|||
mvweqnsstiVmltkleEkgkvkchkYW.Pekg.tetygeltVtleeeeeladyeirtfklkkkkssesreVrqFhFtsWPdhgvpesatslLdlirkvr
EKQaQlvqglgdtwaghPRGPPIVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEYAY
. . . | |||||||||.|||||||..|... |... .| ||...|...|.|| . .| ..||.|.| |. |.
aln.e............pdagPivVhCSaGVGRTGtfividamlerikeektvDiyqyvkalrkqRnamVqteeQYiFiheaileala
|
0051299 |
(Phosphotyrosine protein) phosphatases II |
519-805 |
8e-105 |
345.6 |
In-house |
11-286 (288) |
alignment |
Range on Protein: 519-805
Range on HMM: 11-286/288.0
DQIVQMVKQRGRHGLIKEYADIRNRAPEGTFLHARMRANLTKNRYTDVLCYDHSRVVLAHEDGDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWR
. |......| .||..|. .... | .|. .|.. .||.||||.|.|.||||||.| ..||.|.||||||...|||..|...| ||||||.| ||||
lklvlkllangltglleefeellsllpdltlsaallpenleknRysdilpydhsRVkLsvldgvegsdYinAsyidgynlkrkfIatqgPlpntvedFWr
MIWEQHCLVIVMTTRVMERGRVKCGQYWEPteESSLEFGDYHVRTISVECNEDYMVASLELRNI----KTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFL
|.|||.. |||| |...|.||.|| ||| . ..||..||..|...|.| ..||.| ||..|. ...| |.| |...|.|||.|||.|. ..|.||
mvweqnvrvIvmltklvelgrekcaqYwpl..ggsltygditvtllseevlddytvrtlevtnldlldgdgesrtvthfhytnwpdhgvpdspellldfl
QKVREKQAqlvqglgdtwaghPRGPPIVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEYA
..||...| ..|.|.|||||||.|||||||.||.....|| |. |. ..|...|.|| ...|.|.||.|.. ||.||.
rlvrkala.............sgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlreqRpgmvqtpeqyrfvyealleyl
|
subfamily_Anemone-PTP-6_pd |
Subfamily Anemone-PTP-6 |
519-808 |
6.5e-91 |
299.7 |
In-house |
8-283 (318) |
alignment |
Range on Protein: 519-808
Range on HMM: 8-283/318.0
DQIVQMVKQRGRHGLIKEYADIRNRAPEGTFLHARMRANLTKNRYTDVLCYDHSRVVLAHEDGDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWR
.. |. ... |. | .|| . . | |.. .| .||||...| |||.|| | . .|.| |||||||..|||..|.|||..|.|||.| .||||
eshvrrlresGelllseeyerlsrseetvtslkslepvnkaknryanilaydhtrvkLqmlegeegsDyinanyidGyrrkkayiaaqaPlpetieDfWr
MIWEQHCLVIVMTTRVMERGRVKCGQYWePtEESSLEFGDYHVRTISVECNEDYMVASLELRNIKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVR
|.|||.. |||| |...|||..|. .|| | .. | ..|. .| . .||.. ...... ...| |.| ...||||| |||.|.. .|.....|.
mvWeqnsavivmltqeeergkakvhryW.P.skgsrsygklvvelkeevelsdyvlrefkvtrteeeesrqvrqyhytsWpdegvpesgaslldlvrqvs
EKQAQLVQGlgdtwaghprgpPIVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEYAYSR
. |.. .| |||||||||.||||.||..|| . |... .. |. .||...|.|| .| |||.|.. .|.|. |
kaqqksgag............pivvhCsaGvGrtGvfiavdillerikaealvDvfqtvkqlreqrnlmvqtedqyefiydvllealasg
|
subfamily_PTPRB_pd |
Subfamily PTPRB |
519-805 |
3.8e-88 |
290.3 |
In-house |
13-285 (293) |
alignment |
Range on Protein: 519-805
Range on HMM: 13-285/293.0
DQIVQMVKQRGRHGLIKEYADIRNRAPEGTFLHARMRANLTKNRYTDVLCYDHSRVVLAHEDGDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWR
.. |. .|.. ... .|| .... . . |. .| .|||||..| |||||| ||. .... |||||||...||.... .|.||||||.| .||||
eehvkkmkadsdlrfseeyeelkavgkdqavkaaelavnraknrytnilpydhsrvkLaalkdesgsDYinanyipgynsprefiatqGPlpetvddfWr
MIWEQHCLVIVMTTRVMERGRVKCGQYWePTEESSLEFGDYHVRTISVECNEDYMVASLELRNikTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVR
|.||... .||| |...|.|.||| .|| |..|.. .|| .| .. | ||... .|.... ..|.|.| ...||||||.|||... ..|.|...||
mvwekkssiivmltqlvekgkvkCeeYW.PadeepvlyGdikvtlvaeeeledwvirelkiek..ekeerkvrqyhftsWpdhgvPektktlldfvrtvr
EKQAQlvqglgdtwagHPRGPPIVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEYA
|.. . . . |||||||||.|||||||.|| ....|. . || |.| ..|..|.. .| .||.| | .....
eaiek...........taskrPivvhCsaGvGRtGtfialdrllqaieeedyvdifgivaelReeRnllvqtekqYifihqcvldll
|
subfamily_Urchin-PTP-6_pd |
Subfamily Urchin-PTP-6 |
519-811 |
2.7e-63 |
208.8 |
In-house |
5-282 (515) |
alignment |
Range on Protein: 519-811
Range on HMM: 5-282/515.0
DQIVQMVKQRGRHGLI-KEYADIR--NRAPEgtfLHARMRANLTKNRYTDVLCYDHSRVVLAHEDGDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQD
|. .|.. .. |. .|. |. | |. |. | .|||| ..| || .|| | . . |||.|| .. ... .|||..|||.. . .|
aqfPafvnknrhttlfseefhdlpgpniypq...tvaqeeinfkknryknilPydsvrvklevindnPhsdyfnasyipsfdndkayiasqgPnkasvdd
FWRMIWEQHCLVIVMTTRVMERGRVKCGQYWEPTEESSLEFGDYHVRTISVECNEDYMVASLELrnIKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQ
|||...... |.| |. | ..|||.|| |..|| ..| ..|.|. . . |.. .| |..| | ..|| ||| ||| . ..| ...
fWrlvlqenvttiamvtklkegdkikcgkyWPdkpgdsvkfGsikvelvsleactggikrkltv..lkgddsrtvtqfhfteWPdkGvpkhtssllklik
KVREKQAQLvqglgdtwAgHprgpPIVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEYAYSRGML
.|. .. |. . | |...|||||.|||| .|..| .... .. . |. .|..|| .| | .| .|| | . |. |. . | |
evkadhgqy........t.h....pliihcsaGvGrtGvvisidsvvahakttrmvdvfnfvtnirqkrpylvqtqeqyafiygavledllwrntl
|
0036941 |
(Phosphotyrosine protein) phosphatases II |
520-809 |
3.2e-101 |
333.8 |
In-house |
2-281 (297) |
alignment |
Range on Protein: 520-809
Range on HMM: 2-281/297.0
QIVQMVKQRGRHGLIKEYADIRNRAPEGTFLHARMRANLTKNRYTDVLCYDHSRVVLahedGDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRM
... . |. ....| ||. .. .. . |.. .|. .||.||||.|.|.|||.||.| .||.||||||..||||..|...| ||||||.| |||||
llkllekllflalllkefeellpllllgslsvallpenleknRykdilpydhtRVkl....ddegsdYinAsyvdgydlkrkfIatqgPlpntvedFWrm
IWEQHCLVIVMTTRVMERGRVKCGQYWEPTEESSLEFGDYHVRTISVEC--NEDYMVASLELRNIKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKV
.|||.. |||| |...|.||.|| ||| ..|..||..||..|...||| ..|| . ||. .....| | | |...|.|||.|||.|. .|.|...|
vweqnvtvIvmltelvelgrekcaqywpleegesltygdftvtllsvevvllddytlrtlevtdtgngesrtvthfhytgwpdhgvpespaslldfielv
REKQAQLvqglgdtwaghPRGPPIVVHCSAGIGRTGTFITLDICISRLE---DVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEYAYSRG
|.....| |.|.|..||||||.||.||||..|.....|| |. || .| |.|.||. ..|...||.|.. ||.|. ...
rkvlkll...........psggpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyeallellkkkl
|
0043336 |
(Phosphotyrosine protein) phosphatases II |
520-804 |
1.3e-95 |
315.3 |
In-house |
9-276 (278) |
alignment |
Range on Protein: 520-804
Range on HMM: 9-276/278.0
QIVQMVKQRGRHGLIKEYADIRNRAPeGTFLHARMRANLTKNRYTDVLCYDHSRVVLAHEDGDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRM
. .. .. ....|..|. .... . .|. .|. .| .||||.|.|.||||||.| ...||..||||||..||||......| ||||||.| |||||
kallelllnlktllllefeellsfkl.dtysiallpenkdknrykdilpydhsrvklsllggdldsdYinAsyvdgynvprkfiatqgPlpetvedFwrm
IWEQHCLVIVMTTRVMERGRVKCGQYWEpteESSLEFGDYHVRTISVECNEDYMVASLELRNIKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVRE
.||... .||| |. .|.||||| ||| ..||..||..|.....| ..||.| ||. | ...| | | |.....|||.|||.| .|.||..|||
vwelgvttivmLtelvelgrvkcaqYwp...ggsltygdftvtllkeehlddytvrtlevtnlgdgesrtvthyhylgwpdhgvpeslsllldflkavre
KQaqlvqglgdtwagHPRGPPIVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEY
.. .... |..||||||.|||||||.|......||. |. |. .|...|.||. ..|.|.||.|.. ||.||
al.............edsngpvlVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqRpgavqtpsqyrflyealley
|
subfamily_Anemone-PTP-5_pd |
Subfamily Anemone-PTP-5 |
520-806 |
3.9e-87 |
287.3 |
In-house |
12-284 (319) |
alignment |
Range on Protein: 520-806
Range on HMM: 12-284/319.0
QIVQMVKQRGRHGLIKEYADIRNRAPEgTFLHARMRANLTKNRYTDVLCYDHSRVVLAHEDGDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRM
. ...... | ..| ||. .... .. || .| . | .||||...| ||..||||.. || | ||||||.|.|||......|.||.|| .| .|||||
erlkalastgetllekefkllkeavnd.tfdsaskeenkkknryqnilaydrtrvvlseldgvegsdyinasfidgyqerekfiatqaPlentiedfWrm
IWEQHCLVIVMTTRVMERGRVKCGQYWepTEESSLEFGDYHVRTISVECNEDYMVASLELrNIKTDEI--RNVSHWQFTSWPDYGVPSSAMAMLNFLQKV
.||... ..|| |.. |...||. .|| .|| |.| . | . | |||.. |.| |.|..|. |.|.|.|.|.||| .|| .|...|..|...
vWeeessivvmltklveklkvklkkyw..peenfeeyGrlivtleeeeeledyiirklkl.nkkssevetRevkhfqyteWpdhdvPekatslldllkri
REKQAQLVQGlgdtwaghprgpPIVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEYAY
|. . . .| |||||||||.|||||||.||. . |.. |. |. || ..| || .| |.|| |.. ||.|..
rksrektqsg............PivvhCsaGvGRtGtfivldamlervkeegvlDvfstvsrlRtqRnimvqrpeqYkfiyealleave
|
subfamily_Choan-PTP-1_pd |
Subfamily Choan-PTP-1 |
520-804 |
1.8e-81 |
268.3 |
In-house |
4-275 (281) |
alignment |
Range on Protein: 520-804
Range on HMM: 4-275/281.0
QIVQMVKQRGRHGLIKEYADIRNRAPEGTFLHARMRANLTKNRYTDVLCYDHSRVVLAHEDGDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRM
. .. .| .|.|.||..... . | .. .| .||||... ||..||...... .. .||||||||.|||....|| ||||.|.. ..||.|
khlkqlsqndnaGfieeyeklaaigvdntataskadenvlknrYsnivaYDatrvkvtpneenkntDYinanfvpgykgekeyiatqgPvPaslvafWqm
IWEQHCLVIVMTTRVMERGRVKCGQYWePTEESSLEFGDYHVRTISVECNEDYMVASLELrNIKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVRE
.|||. .||| || .| |..|| .|| | ..|.|..||..|.... | .. |. ..| . .. | |.|.. ..|.||| |||......|.| ..|..
vweqkvsaivmvtreieagklkChrYW.Pddnselkygdvtvkstaeeekatyierkfkl.eresgetreveqlaytaWPdhGvPattkellefrkevlk
KQAQLVQglgdtwaghprgPPIVVHCSAGIGRTGTFITLDICISRLED-VGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEY
. . . |.|.|||||.|||||.|.|| ....|. ..|.. .|...| .| . .| || | ..|....
ltekktk............aplvihCsaGvGrtGtyialDrlvkaveaeleeldvkavvaelrkernlmvqtvvqyefvykavlda
|
subfamily_Urchin-PTPRB-like_pd |
Subfamily Urchin-PTPRB-like |
520-810 |
8.1e-78 |
256.4 |
In-house |
10-284 (288) |
alignment |
Range on Protein: 520-810
Range on HMM: 10-284/288.0
QIVQMVKQRGRHGLIKEYADIRNRAPEGTFLHARMRANLTKNRYTDVLCYDHSRVVLAHEDGDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRM
. |. ..|.| |. .|| . . . . .| | .|||| ..| ||. || | . . . .|||||...||.|.|..||.|||||..| .|||..
akvakksarnrtgfseeynsLaalektksvtagrlavnakknRyrnilpyDekrvklkkleeeagaDYinasyidgekkkkkyiatqgPladtvndfWel
IWEQHCLVIVMTTRVMERGRVKCGQYWePTEESSLEFGDYHVRTISVECNEDYMVASLELRniKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVRE
..|.. ||| | ..|.|. ||..|| |... ..|. | .... ||... .|.| |. . ... ..|...||| ||| |.. .|..|..|
vyenktstivmltelveggktkCeeYW.PdadkpknyGsvtvtlveskeledfvlrkllle..kkkteleitqyqylaWpdhgvPeskapllellrqvkv
KQAQLvqglgdtwaghprGPPIVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEYAYSRGM
. . ||.||||||.|||||||.|| | ..| . |. |||.|.| ||| .| ||.|.. .|.. .. .|.
anqad.............tgpiivhCsaGvGrtgtFialdalidaveeedyiDvagtvaklRkqRallvqtlkqYefiyevllslieedgv
|
subfamily_Anemone-PTP-2_pd |
Subfamily Anemone-PTP-2 |
520-805 |
4.9e-77 |
254.1 |
In-house |
16-290 (298) |
alignment |
Range on Protein: 520-805
Range on HMM: 16-290/298.0
QIVQMVKQRGRHGLIKEYADIRNRAP---EGTFLHARMRANLTKNRYTDVLCYDHSRVVLAHEDGDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDF
..... |. . |. .|. ... | . || ..| ||||.|.. .|.||||| .||.|| |||||| |...||..||.| ||.||..| .||
klaavkkkkkltgyalefqrlnsvsseieeeekevarkpenkkkNRyadiialdssRvvLekedadeesdYiNAsflhaykgrnafiatqaPltetvedF
WRMIWEQHCLVIVMTTRVMERGRVKCGQYWePtEESSLEFGDYHVRTISVECNEDYMVASLELRNIKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQK
|||..|.. .||| | . | ...|. .|| | .| . ..|. .|. | | |..| |.. . |... |.| . .|||||| |||. | ..|..|.|
WrmvteedigtiVmltnleeldktkyhkyw.P.degketygeitvsllskeefadlivrklkvskkkeekerevrqlhftsWpdkgvpenatsvldllrk
VREKQAQlvqgLGDTwaghprgpPIVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEYA
|| .| | |.. |..|.||||.||.|||| .| . |.. . |.. .|. .| .|. ..| .||||.. | .|.
vrasqqq....agnk........pvivqCsaGvgRsGtfiaidsvlervkkeqvvDvfqvvkvlRkkrpgavqteeqYvfiyeavleal
|
subfamily_Sponge-PTP10_pd |
Subfamily Sponge-PTP10 |
520-805 |
4.5e-59 |
194.8 |
In-house |
9-278 (287) |
alignment |
Range on Protein: 520-805
Range on HMM: 9-278/287.0
QIVQMVKQRGRHGLIKEYADIRN-RAPEGTFLHARMRANLTKNRYTDVLCYDHSRVVLAhedgDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWR
..|. ...|. | . .. . . | |. | |||.|..| .| ||.| .| ||||| |.||||.|.|.| ...|. .| ..||.
efvakghakgnegfknqftvleqvtqredevthniasqnkdknRltqilvpdnyrvllk....gehpdyinavfidgykekkafiiaesPmfntarnfWk
MIWEQHCLVIVMTTRVMERGRVKCGQYWePtEESSLEFGDYHVRTISVECNEDYMVASLELRNIK-TDEIRNVSHWQFTSWPDYG-VPSSAMAMLNFLQK
.|.... .||| .. .| . .| ||| | ||.|. .|.|... .. | |..|.. ||..| . ... ..| .|.|.|.. | |.. . .| . ..
liddrnvtaivmlcqekendeevcyqyW.p.eeksvvlGeyniellneevnagyierklevknknkagdkqqvkqyqitnWdstgkvtepqtillvieem
VREKQAQlvqglGDTwaghprgpPIVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEYA
..... . |.| .||||||...||...|. .. | . . |. |. ... | |. |.| .|| | ...||
yktqrkr.....gnt........sivvhCsdtvGrsamfcaaattinkckteGviDvfqvlksqriqkpgsvqtveqykfindivleyl
|
subfamily_Cele-PTP-8_pd |
Subfamily Cele-PTP-8 |
520-807 |
1.3e-36 |
121.2 |
In-house |
8-273 (288) |
alignment |
Range on Protein: 520-807
Range on HMM: 8-273/288.0
QIVQMVKQRGRHGLIKEYADIRNRAPEGTflHARMRANLTKNRYTDVLCYDHSRVVLAhedgDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRM
...| | . || ||| | | |.. . || |..||... . | .|| | |.| ||.|| | | |. | .| || | . .|.|
awirlvlqiaveglkkeyrdspneasidi..idsfianptrdryenlprcditrvkls....ddpdfyiaanvvssakykrrlicaqaPlngtieelWkm
IWEQHCLVIVMTTRVMERGRVKCGQYWEPTEESSLEFGDYHVRTISVECNEDYMVASLELRNIKTDEIRN-VSHWQFTSWPDYGVPSSAMAMLNFLQKVr
. |. ||| ....|.|. | .|. . .| . . . | .| ||. |. | . | . . |.| ||| . .. |..|. .
llesdveyivmlcellekGkeksaeyfPsklGekarigrlctvvkkkradidklvkvsllriskegeekvivkilhlleWdddgvPenylsplrllevl.
ekqaqlvQ---GlgdtwaghprgpPIVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEYAYS
. |||||.|||.|||||.| | . | . || ..| | .| .|| ||.. | . |.
.......kslqk............PivvhssaGvGrtgtlililialeslrlddflgirsllaklreerfkaiqtemqylyvhrcvleelll
|
subfamily_Sponge-PTP11_pd |
Subfamily Sponge-PTP11 |
521-807 |
6.7e-60 |
197.4 |
In-house |
10-285 (290) |
alignment |
Range on Protein: 521-807
Range on HMM: 10-285/290.0
IVQMVKQRGRHGLIKEYADIRNRAPEGTFLHARMRANLTKNRYTDVLCYDHSRVVLA--HEDGDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWR
|. ...|..| ... . . . | | .. | ..||..... || |..| .. | . .|||| ...|||.|..|| ||||...| |||.
fvanghakgnegfrnqfkmldsgesehtvtvgltssnkllnRfanivvyddnritLrpisghkDCtneyinAcyikgykekkqyiatqgpvsntlvdFWk
MIWEQHCLVIVMTTRVMERGRVKCGQYWEPTeESSLeFGDYHVRTISVECNEDYMVASLELRNIKT-DEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKV
.||.... .||| | ..| |.||| ||| . ... .| .... .. | ..|. ||..| .. .. ..| ..|.|.|.. | ..| ....
liwqekvtiivmltniieegkvkCqqYWpds.dtka.ygefsikllneetlneyierklevknknsagakqsvtqyqitnwdstgkvtnpqtillvieem
REKQAQlvqglgD--TwaghprgpPIVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEYAYS
..| . . | .||||||...||...|..... | . . | |. ... |.|. |.| .|| . . ...| .|
yktqrk......rgnt........sivvHCSdtvgrsavfcaaattinkcktegvidvfqvlksqRiqkpgsvqtvqqyqgifqivltylds
|
subfamily_Cele-PTP-6_pd |
Subfamily Cele-PTP-6 |
521-805 |
1.2e-52 |
173.8 |
In-house |
6-277 (307) |
alignment |
Range on Protein: 521-805
Range on HMM: 6-277/307.0
IVQMVKQRGRHGLIKEYADIRNRAPEGTFLHArMRANLTKNRYTDVLCYDHSRVVLAHEdGdEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRMI
|| ..| . |. |. . ...||| .| ..|| ||||.|| | |..|.|. . | |||| ||.. . . .| .|||| .| ..|| |.
wvqrtldkgvqalvdefrvlakktpegvtvea.fsantdknryqdvkcqdkgrivvkfd.g.lasdyihanylgiaikpkkficaqgplentqysfwama
WEQHCLVIVMTTRVMERGRVKCGQYWEPTEESSLEFGDYhVRTISVEC-------NEDYMVASLELRNIKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNF
... ..| .|.| ...|| ||| | | ||. .||||. .. .. .|. ... | ..|.|.. ||| ||| .. .|.
iqekvesvimlckvielakikceqywpleegqklvfgea.pntisvanlgakklapdedlinvttlkvdwaqksrtiqhlqwenwpdrgvpqinltainl
LQKVREKQAqlvqglgdtwaghprgpPIVVHCSAGIGRTGTFITLDICISR-LEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEYA
|. || .. |.|||||||.||.|| ... . . .. . |.. ||..|||| |.|| ||.. | |.||
leavrydtn.................pvvvhcsaGvGrsGtivaislvqdkmiaGinckdmkklveelrsqrhyaiqteaqylylhrvlleyf
|
subfamily_Cele-PTP-14_pd |
Subfamily Cele-PTP-14 |
521-806 |
4.3e-36 |
119.0 |
In-house |
17-291 (310) |
alignment |
Range on Protein: 521-806
Range on HMM: 17-291/310.0
IVQMVKQRGRHGLIKEYADIRNRAPEgTFLHARMRANLTKNRYTDVLCYDHSRVVLAHeDGDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRMI
.. .. | .||.|.| . . .. . .. .. ||||.||.| | ||| | | ||| ||.| ....| .|||| .| ||||||
fiiateklgieglvkqyrkldakqds.sltyeaykkymhknrysdvvcldtsrvklki.dksryedyihanyvktnylrstficsqgplqhtiidfwrmi
WEQHCLVIVMTTRVMERGRVKCGQYWePTEESSLEFGDYHVRTISvECNEDYMVASLEL----RNIKTDEIR------NVSHWQFTSWPDYGVPSSAMAM
... . |.. .|.| || || || |. . .| | .| | |.. . | . |. || || .. ||| |||
fqeraesilllckvgeegrpkcvgyw.pslgvtetygcirvtnls.esseefeicnlavtfvpdnvpvdeqpanlkelrvslikwpnwpdrgvpdekcht
LNflQKVrekQAQLvqglgdtwaghpRGPPIVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEYAY
. |.. ||. | | |||||||..|... ..|.. | .|. |. . ... .|| || . ||.. . | .|
vp..qrl...laqv............rhgpcvvhcsagkdrlyvvvalklkidkldrglkvdaeevktellksraiciqtelqyliidrvriifar
|
subfamily_PTPRG_pd |
Subfamily PTPRG |
522-808 |
1.5e-76 |
252.8 |
In-house |
10-290 (563) |
alignment |
Range on Protein: 522-808
Range on HMM: 10-290/563.0
VQMVKQRGRHGLIKEYADIRNRAPEG--TFLHARMRANLTKNRYTDVLCYDHSRVVLAHEDGDEPS-DYINANFVDGYKQKNAYISTQGPLPKTSQDFWR
| .. | .|. .|. .. .. . . |.. . | ||||.... ||.||| |. | . . ||||||..|||....|.| |||||..| .||||
vaslhadgdigfseefealqsetiskdldaehsqkpenkrKnRylnivaydrsRvklsplpgkkkklDYinAnyidGyqkskafiatqgplkdtfddFWr
MIWEQHCLVIVMTTRVMERGRVKCGQYWePTeESSLEFGDYHVRTISVECNEDYMVASLELRNIKT------DEIRNVSHWQFTSWPDYGVPSSAMAMLN
|||||. .||| | . |||| || .|| |. . |...| .|. |. | | | .| ..|.| |. ..| ....|.||| |||.... |.
miWeqnvaiivmitnlvergrrkcdvYW.Pk.desetygalqvtlieeevlalytvrtlviknlklkkkkqcdteklvrqyhytkWPdhgvPehslpvLi
FLQKVrekqaqlvqglgdTWAGHPRGPPIVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEYAYSR
| .| | . |||||||||.|||||.| || . .... . .. |.. .||.|| . .| .||.| | ||.| |.
fvkks.............saankaeaGPivvHcsaGvgrtGtyivldtllkqiqqenavnvfgflkhiraqRnflvqteEqYiflhdalleaiask
|
subfamily_PTPRK_pd |
Subfamily PTPRK |
522-803 |
8.7e-76 |
249.7 |
In-house |
13-275 (314) |
alignment |
Range on Protein: 522-803
Range on HMM: 13-275/314.0
VQMVKQRGRHGLIKEYADIRNRapegtFLHARMRANLTKNRYTDVLCYDHSRVVLAHEDGDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRMIW
....|. .|. .|| . . . |. | .|||..|.| ||.|||.| ||| ||||||...|.||. .|.| |||||..| .||||...
iallkraegygfkeeyeslfeg.....wdaakkdenreknrsgdilaydrsrvflitidgdpssdyinaalidsykrpaafivtqgPlqetvkdfWrlvy
EQHCLVIVMTTRVMERGRVKCGQYWePtEESSLeFGDYHVRTISVECNEDYMVASLELRN--IKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVRE
...| ||| | ..| ||||| .|| | |... .|| .| ...| .....| . ... . .||| | ..||..|||..|| || ..|.....| .
dencasivmltelvevgrvkClkyW.P.edtev.ygdikvelvetellaelvvrifrveklargqeeirevrqfqflgWpdhdvPvsatgllklvrrvkk
KQAQlvqglgdtwaghpRGPPIVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIE
.|.. . .|||||||| |||||||..|| . .| |. |. .| ..||.. .. .||.|.. ...|
sqee.............eaGrivvhCsaGaGrtGtfiaidivldmieregvvdvfnavktlrsrkvnmveteeqykfiydvile
|
subfamily_Sponge-PTP8_pd |
Subfamily Sponge-PTP8 |
522-805 |
2.7e-74 |
245.0 |
In-house |
13-283 (305) |
alignment |
Range on Protein: 522-805
Range on HMM: 13-283/305.0
VQMVKQRGRHGLIKEYADIRNRaPEGTFLHaRMRANLTKNRYTDVLCYDHSRVVLAHEDGDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRMIW
.. .. .|| ..| . .. .| .... . || .|||.... .|..|. |.... .. ||||||..|||||.|..|| .||||..| .||||.|.
ikearvysdkgleaqykslyee.eesidvg.kkeankaknrlkeitlldddriiltekeslddsdyinasyvdgykrkkkyivaqgPlkntvadfWrliv
EQHCLVIVMTTRVMERGRVKCGQYWEPTEESSLEFGDYHVRTISVECNEDYMVASLELRN-IKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREK
| . .||| |...| |. || ||| .. . |||...| | . .||. |.. . . .| |.|...|.|.||| ||| .| ..|.....|...
eekvstivmltklveggkdkCrqYWpesktekkefgefsvelksektasdyieRklkisiededkesrtvlqyqltdWPdhGvpqfatsllslikrvqkd
QAQlvqglgdtwaghPRGPPIVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEYA
| . .| |..||||||.||||.||..|| . ||. .. |. . . ..||.| . .| |||||.| || |.
qkk............dkgvpllVhCsagvgRtGvfiavdialerlkkEevvdvfevlkqlRskrmkmvqtldqYvflhdaldeli
|
subfamily_PTPN6_pd |
Subfamily PTPN6 |
523-806 |
3e-76 |
251.3 |
In-house |
18-298 (306) |
alignment |
Range on Protein: 523-806
Range on HMM: 18-298/306.0
QMVKQRGRHGLIKEYADIRNRAPEGTFLH--ARMRANLTKNRYTDVLCYDHSRVVLAhEDGDEPSDYINANFVDGY--KQKNAYISTQGPLPKTSQDFWR
. .. .. |. .|. ...... . .. . .. | .|||| .| .||.||.|. |.. |||||||.... .....||.||| |..| .||||
keeeslekagfeeefeelqqeeakkllsrkegakpenkeknryknilPfDhtrvilk.epsvpgsdyinanyikkevkgsdksyiatqgclettvsdFWr
MIWEQHCLVIVMTTRVMERGRVKCGQYWePTEESSLEFGDYHVRTISVECNEDYMVASLELR-NIKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKV
|.|.... ||||||. .|||. || .|| |.||.. |.|...|...| . ..||.. .| . . | .| |.| ...|.|||| |||.. |.|.||..|
mvwqensrvivmttkevErgkekCarYW.PdeeekeeyGkisvtnvseksladYilRelsvskkkkkkeerevfqyhfksWPdhgvpkdpgavLdfledv
REKQAQLVqglgDTwaghpRGPPIVVHCSAGIGRTGTFITLDICISRLEDVGT---ADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEYAY
..|| .| .. . ||||||||||||||||| .|| .. .| |. ||. .|...|.|| .|. .|| | . |. .|
nrkqeele....ea.....eagpivvhCsaGiGRtGtfiviDillkliekkgldadidiqklvksvreqrsglvqteqqykfvykaikkyie
|
0047943 |
(Phosphotyrosine protein) phosphatases II |
524-805 |
3.2e-100 |
330.3 |
In-house |
5-272 (273) |
alignment |
Range on Protein: 524-805
Range on HMM: 5-272/273.0
MVKQRGRHGLIKEYADIRNRAPEGTFLHARMRANLTKNRYTDVLCYDHSRVVLahedGDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRMIWEQ
. |. |...|..|. .... |..|. .|.. .|..||||.|.|.||||||.| ||..||||||..||||..|...| ||||||.| |||||.|||
lekllgltllleefelllslkplltysvallpenkdknrykdilpydhsrvkl....gdggsdyinAsyvdgynlkrkfiatqgPlpntvedfwrmvweq
HCLVIVMTTRVMERGRVKCGQYWEPTEES-SLEFGDYHVRTISVECNEDYMVASLELRNIKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREKQA
.. |||| |...|.||.|| ||| ..... ||..|...|...|.| ..||.| |||.|..|.| | | |...|.|||.|||.| .|.|...||....
nvrviVmLtelvelgrekcaqYwpleggelsltygkftvtllseetkddytvrtleltnlgtgesrtvthfhytgwpdhgvppslesllefielvrkale
QLVQGlgdtwaghprgPPIVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEYA
.|... .|.|||||||.|||||||.||.....|| |. |. .| ..|||| ...| |.||.|.. ||.||.
alpsn...........gpvvVHCsaGvgRtgtfialdllldqlekeggvdvleavkllrsqRpgmvqtpeqyrflyealleyl
|
subfamily_Ptp69D_pd |
Subfamily Ptp69D |
525-806 |
5.5e-75 |
247.3 |
In-house |
16-287 (307) |
alignment |
Range on Protein: 525-806
Range on HMM: 16-287/307.0
VKQRGRHGLIKEYADIRNRAPEGTFLHARMRANLTKNRYTDVLCYDHSRVVLAHEDGDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRMIWEQH
|. .||.||| . .| . . . |. |||| |. .|. ||.|.. |.| ||||||.|. |||.|. .| |.|. | .||||||.||.
rkrdtdfglakeyekLeareidkstkvsekkenalknRyedikafDktRvkLkkingkedsdYinasfikgykekkkfiaaqdPveatigDfWRmiaeqe
CLVIVMTTRVMERGRVKCGQYWePTEeSSLEFGDYHVRTISVECNEDYMVASLELRNIK-----TDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVRE
.||| . . | | || .|| | | ..|| |...| | .||. .|.. ..| .. |.| ...|.|.|. || .| ..|.....|||
vtlivmlsnlteknrkkcakYW.pie.devqygdilvklvseekhsdyiiReldvskkkeesgevedsrkvvqyhytgWkDskvPevargllklieqvre
KQAQLvqglgdtwaghprGPPIVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEYAY
. . ||||||||| ||.|.|..||. . .|. ..|| || ..|||| .| .||||.. ||..|
lykln.............rsPivvhCsaGvgrsgifvaldsllqqlkaedkvdifetvkdLrsqRnllvqsleqYvflyralldyss
|
subfamily_Cele-PTP-20_pd |
Subfamily Cele-PTP-20 |
525-807 |
2.4e-55 |
182.2 |
In-house |
21-285 (290) |
alignment |
Range on Protein: 525-807
Range on HMM: 21-285/290.0
VKQRGRHGLIKEYADI-RNRAPEGTFLHARMRANL--TKNRYTDVLCYDHSRVVLahEDGDePSDYINANFVDGYKqkNAYISTQGPLPKTSQDFWRMIW
| ... ..| ||| . . | . . . .| .|||| || | | .||.| .|| . ||. ||.|.| | .| |||.| .| |.|||.
vvkknvdelakeyleklkpylpvqylerkifdkntefkknrykdvvcndktrvil..kdGy.dGdyvhanyvkGlk..amfiltqGalkdtvidiwrmvl
EQHCLVIVMTTRVMERGRVKCGQYWEPTEESSLEFGDYHVR-TISVECNEDYMVASLELRNIKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREK
... .||| ..| |. || ||. .| | ||.. | . . . ... . | .|. .. . |.. |||| |. |..|.| |. .|.
qekvaaivmlceliedGkakceqyypekeGevltfGeitvlcseeddkdaniikktlsvrdkdsGkehklkhlkikswpdksvalstlallrtlrilrka
QaqlvqGlgdtwaghprgpPIVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEYAYS
| |.||||||||||||||....... | | |. ..| .| |. |.|. ||. .|... .
s.....G............pvvvhcsaGiGrtGtfvaievglqilldGkeldlldlvralrnsrlnsvqvdiqylalveilldlGkd
|
subfamily_Urchin-PTP-3_pd |
Subfamily Urchin-PTP-3 |
526-808 |
1.4e-62 |
206.7 |
In-house |
18-291 (325) |
alignment |
Range on Protein: 526-808
Range on HMM: 18-291/325.0
KQRGRHGLIKEYADIRNRAPEgTFLHARMRANLTKNRYTDVLCYDHSRVVLAHEDGDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRMIWEQHC
| . . |. .|. . . . .. | .| |||. .|. .|.||||| . | ||||||... .|.|. ....| ||..| .|.||.. . .|
kaqdqdgfahefgllpsddgi.akkvamkpenkaknrfknvvaldksrvvletkkddpssdyinasylrddkkkdvflaaqaPltatindlWrlvldWrc
LVIVMTTrVMERGRVKCGQYWEPTEESSLEFGDYHVRTISVECNEDYMVASLELRNIKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREKQAQLV
|.|.. ... | .| .|| | .|| .|. ...| ||. |.....| | | | .|. ||.| ||. .....|| | . . ..
svvvvln.eldlgkdrcavywpkemgksktfGglevklrtieeisdyvhrvldvkqvkkGetrsvkqfqlqswddmGvqkrpatlisilqlvkavservt
QglgDTWAghprGPPIVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEYAYSR
.| | ||.||||||.||||.||.| . .. . || | |.|.| .| .. |||.... ||.|. |
a...ntka....stpilvhcsaGvGrtGvfislysalakvieesrvdifgfvkklrkdrpsmvetvdqyiliyealveaymsg
|
subfamily_Choan-PTP-4_pd |
Subfamily Choan-PTP-4 |
530-800 |
2.8e-54 |
179.0 |
In-house |
6-290 (297) |
alignment |
Range on Protein: 530-800
Range on HMM: 6-290/297.0
RHGLIKEYADIRNRAPEGTFLHARMRANLTKNRYTDVLCYDHSRVVLAHedGDEPSDYINANFVDGY--KQKNAYISTQGPLPKTSQDFWRMIWEQHCLV
|. | .|. . . | ..| |. . | ||||.|.| .| .|| | . .|||||..| ... || .|||| .| .|||....|| |
rkeleaekdllldeargesfssakrnsslrknryrdilatddtrvkllr..viterdyinadyvvfpdeeadlkyilaqGplsatvddfwtlvaeqdvrv
IVMTTRVMERGRVKCGQYWEPTEESSLEFGDYHVRTISVECNEDYMVASLELRNIKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNF--------------
||| ... | || || || ... |. ||. | .| .| | ||. | .| | | | || ||||.|||| . |
ivmvaklqedGrdkcapywpsvvqerlkagdvvveflsstsdefdrviltelqliyrsesrvvrhvqflswpdhGvpsdledlvrfqaqvcscciavpmm
LQKVREKQAQLVQGLGDTWAGHPRGPPIVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLA
| | | .. | | .|| ...||||||.||.| . |. ...| |.. ....|.||| .| .|. ... |
lalvemftamvflqleslraemprnayllvhcsaGvGrsGvvvlsdvilaklrkkripdvaailsilreqrarlvqtleqfellyda
|
subfamily_Sponge-PTP9_pd |
Subfamily Sponge-PTP9 |
531-804 |
1.6e-42 |
140.2 |
In-house |
15-292 (301) |
alignment |
Range on Protein: 531-804
Range on HMM: 15-292/301.0
HGLIKEYADIRNRAPEGTFLHARmRANLTKNRYTDVLCYDHSRVVLAHEDG--DEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVI
... ..| .... .. . .. . .| . ||. .. ||. |..|... .||||...|||..|...| .|||. || .||||.||... |
nkfeeqykelkegedksctvgls.eenkalnrfknitvyddnriilkpkpnldlcqreyinasyidgysekkkfiaaqgpmkktlvdfWrliwqekpvsi
VMTTRVMERGRVKCGQYWEPTEESSLEFGDYHVRTISVECNEDYMVASLE-----------------LRNIKtdEIRNVSHWQFTSWPDYGVPSSAMAML
|| | |. . || |||. .|..| ||| .| .. |... .| .. | . ..| .| |.||. || .|
vmvtnlkegtkskceqywpnseaeseefgpftvtlvneqvyPdfvirqlnvkiqdgsnngyierkfkvksdk..sswdvlqlqvtdWpqdGvvreprtvL
NFLQKVREKQAQLvqglGdtwaghprGPPIVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEY
. ...| .| . | | |.|||||....|.|......| . | |. . .. .| .. .. .||.. . .. .|
qviddvihrqqki....g........ggpvvVHCSdtVsrsGvYcsvsiglEQckaegVVdvfqvtkavrrskpgaVtTLeqytsiydvidmy
|
0046845 |
(Phosphotyrosine protein) phosphatases II |
532-807 |
1.9e-100 |
331.1 |
In-house |
1-276 (284) |
alignment |
Range on Protein: 532-807
Range on HMM: 1-276/284.0
GLIKEYADIRNRAPEG--TFLHARMRANLTKNRYTDVLCYDHSRVVLAHEDGD-EPSDYINANFVDGY-----KQKNAYISTQGPLPKTSQDFWRMIWEQ
||..|. ... . .. .|.. .||.||||.|.|.||||||.| ..||| | ||||||..|||| ..|...| ||||||.| |||||.|||
gleeefeellsltvklllslsvallpenlsknRykdilpydhsRVklksldgdledsdYinAsyvdgydldltyikkkfIatqgPlpntvedFwrmvweq
HCLVIVMTTRVMERGRVKCGQYWEPTeESSLEFGDYHVRTISVECNEDYMVASLELRNIK-TDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREKQA
.. |||| |. .|.||.|| ||| .. ...|..||..|...|.| ..||.| |||.|.. |.| | | |...|||||.|||.|. .|.||..||| .
nvrvIVmltelvengrekcaqYwple.gevltygdftvtllseevkddytvrtleltnlgytgesrtvthfhytswpdhgvppspedlleflrlvrelle
QlvqglgdtwagHPRGPPIVVHCSAGIGRTGTFITLDICISRLEDVG---TADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEYAYS
. .|.|.|||||||||.|||||||.||.....|| | . |. ..| ..|.|| ...|...||.|.. ||.||...
n...........lpgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvqtleqyrfvyealleylkl
|
subfamily_PTPN3_pd |
Subfamily PTPN3 |
533-801 |
2.6e-76 |
251.2 |
In-house |
17-271 (280) |
alignment |
Range on Protein: 533-801
Range on HMM: 17-271/280.0
LIKEYADIRNRAPEGTFLHARMRANLTKNRYTDVLCYDHSRVVLAHEDgdEpsDYINANFVD----GYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVI
..... . . |. . .||. .||.|||| |.| ||. || | ... ||||||.|. . .. | ||.|||||.||..|||.|.|||.. .|
vlaqfeqlyrkkpglaisaarkpenlsknryrdilpydatrvklkese..t..dyinanyvnmeipstglvnryiatqGPlaktatdfWqmvweqkssli
VMTTRVMERGRVKCGQYWePTEESSLEFGDYHVRTISVECNEDYMVASLELRNIKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREKQaqlvqgl
|| | ..||||||| ||| |..| .||.|...|. . .... |.. | |.. .|.| |.. . |...||| |||... .|.|...||...
vmlttlverGrvkChqyW.PetedeleygefsvkcekedetksyvlrelvlkdketkeerkilqlqylaWpdhgvPddsadflefvervrklr.......
gdtwagHPRGPPIVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLAL
. . |.|||||||||||| .|.|..... .| . | ..| ||| .| ..|| | |.
......sgkeePvvvhCsaGigrtGvlilletalalieaaepvypldivrtmrdqramlvqtasqykfvCeai
|
subfamily_Urchin-PTPRA_pd |
Subfamily Urchin-PTPRA |
533-808 |
2.7e-71 |
235.5 |
In-house |
36-295 (319) |
alignment |
Range on Protein: 533-808
Range on HMM: 36-295/319.0
LIKEYADIRNRAPEGT-FLHARMRANLTKNRYTDVLCYDHSRVVLAHEDGDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMT
| |. . ....... .| . | |||....| .|...| | . .| | |||||| ||.||..|. ||..||||. | .||||||||..| ||.
levefrracklgvnladqtfanldqnkdknriinilafdknvvklerliGeefsdyinasfvtGyqrkdkyiaaqGPldntladfWrmiweyncstivll
TrvmergRVKCGQYWePtEESSLEFGDYHVRTISVECNEDYMVASLELRN-IKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREKQAQLvQglgd
| . || ||| | . . . ..|. ||| ..|.| ..|| . | .||.. . | |||.||| ... .. ...||| . . .
t......kdkcsqyw.p.lkivikeerfkvkvdsveetaeyvvrdielsedgkekdirkitqfhflGwpdvGvpdypsdlmrlvkkvrhltske.n....
twagHPRgpPIVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIE-YAYSR
|.. .||||||||.||||..|.||. ..|... |. .|. .| || .| || |.. ||.| . ...
....hra..nivvhcsaGvGrtGvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysalleehlfgh
|
subfamily_CG7180_pd |
Subfamily CG7180 |
533-804 |
1.6e-53 |
176.3 |
In-house |
18-289 (296) |
alignment |
Range on Protein: 533-804
Range on HMM: 18-289/296.0
LIKEYADIRNRAPEGTFLHARMRANLTKNRYTDVLCYDHSRVVLAHEDGDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTT
. | . .| |. .. |. |||. .|. ||. |||| . ||.| |||||| .||.. .|..|| |..| .| ..|||....... .|. |
eyklelkltprleigdCagglrkenreknrdvkvvPyDynRvvLekldGeeksdYinavyvdsflkkkeyivteapkketvdefWrlvydeeisavvvLt
RVMERGRvKCGQYWEPTEesSLEFGDYHVRTISVECNEDYMVASLELRNI----------KTDEIRNVSHWQFTSWPD-YGVPSSAMAMLNFLQKVREKQ
.... . .. .|| .. ..|. | ..... . . | . | | | . |.| |. ||.|. |.......|| .
ktfdfak.mypsywpnks..keqygeifveiveekqyanlkirtfkltkkivalteqekqvkaetRivklfqlteWeledkvPlstnalielrrrvrlwr
AQLvqglgdtwAGHPRGPPIVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEY
. .| |.||..| | .|.| ....|... .| . |. . | ..| .| ... ..| .. | |.
ekv........dedpeegPvvvvssdGasRsGvylaidanlelvekeeevdvFeavktlrrsRpqLvenveeYkyiYdvllea
|
subfamily_Cele-PTP-11_pd |
Subfamily Cele-PTP-11 |
533-813 |
3.3e-30 |
99.9 |
In-house |
21-284 (312) |
alignment |
Range on Protein: 533-813
Range on HMM: 21-284/312.0
LIKEYADIRNRAPEGTFlHARMRANlTKNRYTDVLCYDHSRVVLAhedGDEpSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTT
| ||| . | .. | .. . ||| .. |.| | || ||| || |||| . . ...||||| .|. ||.. . |.. .
ltkeykavgnivsdsec.taflkfk.dlnrypniqcwdrgrftla...gde.nfyihanfvkictkperfvctqgplentcthfwqlalslgstsiillc
RVMERGRVKCGQYWEPTeESSLEFGDYHVRTISV-----EC--NEDYMVASLELRNIKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREKQAqlv
..| | || .| . ... |. | | .. .. | . | . .. |.|..||||.|.| | . | .| |. .
gfvedgsekcakyisdi.vgfvdledhrvyteycteieiggkskdkithrvlkvvvkatgqesklnhyqwaswpdhgmpdscdtalrllsavkkdkk...
qglgdtwaghprgpPIVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEYAYSRGMLQT
|.. |||||.|||||.. .. |. | ... . .| .|| |... |||.. ...|. ||.|. .
..............pviahcsagvgrtgtlaliesmiaalrhprkqnvkdsfvllrkdrarsvrvfpqyvyalrcvleflyskglykr
|
DSPc_SM00195 |
|
534-805 |
2.3e-92 |
304.4 |
In-house |
3-262 (263) |
alignment |
Range on Protein: 534-805
Range on HMM: 3-262/263.0
IKEYADIRNRAPEGTFLHARMRANLTKNRYTDVLCYDHSRVVLAHEDGDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTR
.|. .... ... .. .|. .| .||||...|.|||.|| | .|...|.|||||||...|...|..|| ||||||.| .|||||.||... .|||.|.
keefekleestspketteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivmlte
VMERGRVKCGQYWEPTEESSLEFGDYHVRTISVECNE-DYMVASLELRNIKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREKQAQLvqglgdtw
.|.|. || .||. ..... .||...| ...|| . .. . |||.. ...| |.| ..|...||| |||.|.. .|..|..|.... .
eeengkekcdrywpeesggketfgkisvklvevekkkdeiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkksksts........
aghprGPPIVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEYA
.|||||||||.||||||.|.||..|.||. . || .|...|.||. ..|. .|| |.. |..||.
.....sgpivVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaileyi
|
PTPc_SM00194 |
|
534-805 |
2.3e-92 |
304.4 |
In-house |
3-262 (263) |
alignment |
Range on Protein: 534-805
Range on HMM: 3-262/263.0
IKEYADIRNRAPEGTFLHARMRANLTKNRYTDVLCYDHSRVVLAHEDGDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTR
.|. .... ... .. .|. .| .||||...|.|||.|| | .|...|.|||||||...|...|..|| ||||||.| .|||||.||... .|||.|.
keefekleestspketteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivmlte
VMERGRVKCGQYWEPTEESSLEFGDYHVRTISVECNE-DYMVASLELRNIKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREKQAQLvqglgdtw
.|.|. || .||. ..... .||...| ...|| . .. . |||.. ...| |.| ..|...||| |||.|.. .|..|..|.... .
eeengkekcdrywpeesggketfgkisvklvevekkkdeiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkksksts........
aghprGPPIVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEYA
.|||||||||.||||||.|.||..|.||. . || .|...|.||. ..|. .|| |.. |..||.
.....sgpivVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaileyi
|
subfamily_PTPN13_pd |
Subfamily PTPN13 |
534-803 |
4.3e-69 |
227.8 |
In-house |
14-267 (273) |
alignment |
Range on Protein: 534-803
Range on HMM: 14-267/273.0
IKEYADIRNRAPEGTFLHARMRANLTKNRYTDVLCYDHSRVVLAHEDGdepsdYINANFVDGY--KQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMT
.|. ..|. | | .. ..| .|||| .|| ||..|| | | | ||||... |.. || .|||||.| .|||.|.|||.. ||.|
aeefkelrelkpldtcevgkkkenkdknryrnvlPydetrvklgdegg.....yinaslikvpvgkdeyeyiacqGPlPetvkdfwqmvweqkaeviamv
TRVMERGRVKCGQYWEPTEESSLEFGD-YHVRTISVECNEDYMVASLELRNIKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREKQAQlvQGlgd
| |.|.||| .|| .....| . ..|. . |. ... | .|....... | |.|.| .|..|||.||||||. .|.|...||. | . .|
tlekekgkvkchrywPesknkklkvsnrlevellkvqkldgfvvralavkdsesgesrevahlnfvkwPdhgvPssaaellqfvaevrrlqtd..ag...
twaghprgpPIVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIE
||||||||||||.||.||.|. . .| |.. .|.|.| || .| |||.|.. |..|
.........PivvhcsaGiGrsGtlitidvvlglierdkefdvkeivrklreqrqgvvqtkdqyifvykaile
|
subfamily_PTPRN_pd |
Subfamily PTPRN |
535-803 |
3e-59 |
195.2 |
In-house |
33-290 (297) |
alignment |
Range on Protein: 535-803
Range on HMM: 33-290/297.0
KEYADIRN-RAPEGTFLHARMRANLTKNRYTDVLCYDHSRVVLAHEDGDEPSDYINANFV-DGYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTT
||. . . .| . | |. |..|||...|| |||||| | .| .| |||||| .. | .. |||.|||||..| |||.|.||| . |||. |
kewealcayeaepstkevakaeknvkknrskavlpydhsrvklkeeasaeksdyinasaildhdprapayiatqgplastvadfwqmvweqGvvvivnlt
RVMERGRVKCGQYWePtEESSLEFGDYHVRTISVEC-NEDYMVASLELRNIKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREkqaqlvqglgdT
|. | | .| .|| | .| | .. | |. .| .||.| |. |.|..|.| | |. . | |||. |||.|| ..|.| .|| .
rleeegvkqckryw.p.deGsevyhiyevhlvsehiwcddylvrsfylknlqtsetrtvtqfhflswpeegvPasaksllefrrkvnk...........s
WAGhpRGPPIVVHCSAGIGRTGTFITLDICISRLE-DVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIE
. | | |||||||.| ||||..| .|. ..|| | || |.|..| ||. .. ||. |. |..|
yrG..rscpivvhcsdGaGrtGvyilidlvlnrllkGvkeidiaatlehlrdqrpglvktkdqfefaltavae
|
0045098 |
(Phosphotyrosine protein) phosphatases II |
536-805 |
3.7e-85 |
280.9 |
In-house |
12-272 (278) |
alignment |
Range on Protein: 536-805
Range on HMM: 12-272/278.0
EYADIRNRAPEGTFLHARMRANLTKNRYTDVLCYDHSRVVlahedgdepsDYINANFVDGYkqKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVM
|. .. . .....| .. || ||||.|.|.||||||. |||||...||| ....| ||||||.| .|||||.||... |||| |...
efefllllgipseitpalylgnldknRykdilpydhsrVk..........dYINAsyidgy..pkkfIatqgPlpstvadfwrmlwelgitvivmltelv
ERGRVKCGQYWEPteESSLEFGDYHVRTISVECNEDYMVASLELRNI----KTDEIRNVSHWQFTSWPDYGVPSSA--MAMLNFLQKVREKQAQLVQGLG
|.||.|| ||| . ..||..||..|...|.| ..|| . |...|. ...| |.| |.....|||.||||. . .|..|. .|| ...|.. |.
elgrekcaqywpe..ggsltygdftvtllseevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslll
DTWAGHPRGPPIVVHCSAGIGRTGTFITLDICISRLeDvGTADIRGTVEKIRSQRAY-SIQMPDQYVFCHLALIEYA
.. ...| |..||||||.|||||.. .......| . |. |. .|...|||| . ..|...||.|.. .|.|.
sslllldsggpvlVHCsaGvgRtGtlvaaylmlell.e.ggvdlleavkelrsqRpglavqnleqyrflyefllell
|
subfamily_PTPN1_pd |
Subfamily PTPN1 |
537-804 |
2.3e-73 |
241.5 |
In-house |
12-270 (290) |
alignment |
Range on Protein: 537-804
Range on HMM: 12-270/290.0
YADIRNRAPEGTFLHARMRANLTKNRYTDVLCYDHSRVVLAHEDGdepsDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVME
| |||. | . . .|.. .| ..||| || |||||..| ..| |||||..|. . | || ||||||.| . ||.|.|||.. .|| .|.|
yldirkeasdfptreaklpenrnlnryrdvspydhsrikleradn....dyinaslveleeakrsyiltqGPlpntvdhfWqmvWeqkskavvmlnkvve
RGRVKCGQYWEPTEE-SSLEFG--DYHVRTISVECNEDYMVASLELRNIKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREKQaQLVQGLGdtwa
....|| ||| || ..|.. ..|. || | .. |.| ||| |.||.| |...|. .|.|||.|||.| |.|.||.|||| |.. |
keqikcaqywPqgeeekellledtklkvkliseerksyytvrllelenlktqetreilhfhyttwpdfgvpespaaflkflfkvresG.slssdvG....
ghprgpPIVVHCSAGIGRTGTFITLDICISRLEDVGT---ADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEY
| |.||||||||.|||. .| |. ..|. . ||. .. ..|..| || .|| | .||..|
......pavihcsaGiGrsGtfclvdtclvliekkddlssvdikkvllelrkyrlGliqtadqlrfsylaileG
|
subfamily_Urchin-PTP-8_pd |
Subfamily Urchin-PTP-8 |
537-809 |
3.2e-70 |
231.9 |
In-house |
4-260 (284) |
alignment |
Range on Protein: 537-809
Range on HMM: 4-260/284.0
YADIRNRAPEGT-FLHARMRANLTKNRYTDVLCYDHSRVVLAHEDGDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTrvm
. . .....|| .| . | |||....| .|...| | . .| | |||||| |. ||..|. ||.|||||. | .||||||||..| ||. |
frracklgvngtdqtfanldqnkdknrighilafdknvvklerliGeefsdyinasfitGyqrkdkyiatqGPldntladfWrmiweyncstivllt...
ergRVKCGQYWePtEESSLEFGDYHVRTISVECNEDYMVASLELRN-IKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREKQAQLvQglgdtwag
. || ||| | . . . ..|. ||| |.|.| ..|| . | .||.. . | |||.||| ... .. ...||| . . .
...kdkcsqyw.p.lkivikeerfkvkvdsveeseeyvvrdielsedgkekdirkirqfhflgwpdvgvpdypsdlmrlvkkvrhltske.n........
HPRgpPIVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIE-YAYSRG
|.. .||||||||.||||..|.||. ..|... |. .|...| || .| || |.. ||.| . ...
hra..nivvhcsagvgrtgvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysalleehlfghs
|
subfamily_Sponge-PTP4_pd |
Subfamily Sponge-PTP4 |
539-597 |
2e-08 |
28.2 |
In-house |
21-78 (244) |
alignment |
Range on Protein: 539-597
Range on HMM: 21-78/244.0
DIRNRAPEGTFLHARMRANLTKNRYTDVLCYDHSRVVLAHEDgDEPSDYINANFVDGYK
. ... | | . || ||||| ..| .|..||.|. | |||||||...| .
glsdhtreflqtnavlsanatknryinilpfdetrvilsssk.kegsdyinanyiqgsq
|
0049772 |
(Phosphotyrosine protein) phosphatases II |
542-805 |
5e-49 |
163.1 |
In-house |
31-280 (314) |
alignment |
Range on Protein: 542-805
Range on HMM: 31-280/314.0
NRAPEGTFLHARMRANLTKNRYTDVLCYDhSRVVLAHEDGDEpSDYINANFVDGYkqkNAYISTQGPLPKTSQDF----------WRMI--WEQHCLVIV
. ||.|.| |. .| .||||.|.|..| .||.| .... ||||||..|||. ...| |||||. | || |||. ..... .||
svlpeltilvadlflnrdknryldilpad.nrvilpglpvsg.sdyinasyvdgf...lkfIatqgpleitvvdfreepvlyyngwrmvlrgdlnvrdiv
M---------------------TTRVMERGrvkcgQYWEPTEESSLEfgdyhvrtisvecnedymvaslELRNIKTDEIRNVSHWQFTSWPDYGVPSSAM
| ......| .. . . |. | . . . |.. .. . .||...|....
msrdevladelsrLdaAlgKtpllildgng.....neptaadlellk......................eelydpelferlgikylripvpDgsaplled
aMLNFLQKVREKqAqlvqglgdtwaghpRGPPIVVHCSAGIGRTGTFITLDICISRLedvGTaDIRGTVEKIRSQRA-----YSIQMPDQYVFCHLALIE
.. ||. ..| .| |..|||.||.||||||.........| | ... ..| .|..| .|....||.|.. || |
.fdeflefieea.d..............kggpvlvHCkaGkgRtgtfvvaaylmkll...gv.sleealedvrlkRpinpnpgfieqleqyefilealle
YA
|
yl
|
subfamily_egg_pd |
Subfamily egg |
542-802 |
1.1e-34 |
114.5 |
In-house |
25-267 (307) |
alignment |
Range on Protein: 542-802
Range on HMM: 25-267/307.0
NRAPEGTFLHARMRANLTKNRYTDVLCYDHSRVVLAHEDGDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERgrVK
. . | .. .| ||.| | | | | ||| | . | |.| || |.| | .| .| || | .|||||...... ||| | | .
esvdeislttaasdnnlekarskrvhckdssrvklelrrGqylddfihanrvkGkpllnefilaqaplkntvddfwrmvfqeevqyivmltsrkes..er
CGQYWEPTEESSLEF--GDYHVRTISVECNEDYMVASLELRNIKT-DEIRNVSHWQFtswpDYGVPSSAMAMLNFLQKVREKQAqlvqglgdtwaghprg
| || .|. || . | ... .. |. . | . .|. . . || | . ||| |. | |. |.|.|.
ceyywpkaesdslvtvpGslrienlkvdskadplfrvtklklvGgddeerflehwqg....dvnnssdvysplrvlrklrnlsk................
pPIVVHCSAGIGRTGTFITLDICISRLED--VGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALI
|.||.. |. ...|.....| . | . .. .| .| .| .|.. . .|.| . ..
.pvvvqdilGvskaatlvaieiallsllrGpitkslvlravvflrlrrrlsvesvllylfvyrlvl
|
subfamily_Choan-PTP-3_pd |
Subfamily Choan-PTP-3 |
547-806 |
3.4e-62 |
204.8 |
In-house |
28-278 (287) |
alignment |
Range on Protein: 547-806
Range on HMM: 28-278/287.0
GTFLHARMRANLTKNRYTDVLCYDHSRVVLAHEdGDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERGRVKCGQYW
|| | |. ||||.||| .|..||.|..| |. |||||||.| .|....|.|..|||.. | .||||...|.. .... || .| .| || .||
atfkaaeelaavkknryadvlPiddtrvllsae.gelGsdyinanyvasytddeafiaaqgPiaatvrdfwravletrsasvitmtreveearlkcykyw
ePTEESSLEFGDYHVRTISVECNE-DYMVASLELRNIKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREKQAqlVQglgdtWAGHPRGPPiVVHC
| | . | | | .. . | .| | .| | ...| | | | .. |||| ... .|.... | .|... .. . ||. |||.
.PerevPmrvGGysvvlldydikePeygvralrlidletrearvvkqldllswPdkvlaPtavglirfvldvkqhie..la.....rdasevGPl.vvhd
SAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEYAY
..||||.|..... ...|||||.| |. .| ..| .|| .| . |. . ||. |
dvGiGrsGillatlvlvsrledlGrvdvaavvirlreyraalvqavvqlrllyealvtyyk
|
0040439 |
(Phosphotyrosine protein) phosphatases II |
548-805 |
7.3e-88 |
289.6 |
In-house |
2-246 (249) |
alignment |
Range on Protein: 548-805
Range on HMM: 2-246/249.0
TFLHARMRANLTKNRYTDVLCYDHSRVVLAHEDGDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERGRVKCGQYWE
.. .|.. .|. ||||.|.|.||||||.| . .| ..||||||...|||..|...| ||||||.| |||||.||... |||| |. .|.||.|| |||
eysvallpenkdknrypdilpydhsrvklsilpglflsdyinAsyidgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqywp
PteESSLEFGDYHVRTISVECNEDYMVASLELRNIKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREKQAQLvqglgdtwaghPRGPPIVVHCSA
. ..|||.||..|...||| ..||.| ||| |....| | | |.|.|.|||.|||.| .|.|...||. ...| |.| |..|||||
l..ggsleygdftvtllsvevkddytvrtleltnlydgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleel...........pkggpvlVHCsa
GIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEYA
|.|||||||........|| .. |. .|...|||| ...|.|.||.|.. ||.|.
GvgRtGtfiaaylmleqlekelgvdleeavkllrsqRpgavqnpeqyrflyeallell
|
0037934 |
(Phosphotyrosine protein) phosphatases II |
549-804 |
4.8e-79 |
260.6 |
In-house |
2-241 (243) |
alignment |
Range on Protein: 549-804
Range on HMM: 2-241/243.0
FLHARMRANLTKNRYTDVLCYDHSRVVLahedgdEPSDYINANFVDGYKQknaYISTQGPLPKTSQD----FWRMIWEQHCLVIVMTTRVMERGRVKCGQ
| .|.. .||.||||.|.|.||||||.| |.|||||||....... .| ||||||.| .| ||||.||... |||| |. .|.||.|| |
fsiallpenlsknrysdilpydhsrvkl......egsdyinanliyvtpr...liatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaq
YWEpteeS-SlEFGDYHVRTISVECNEDYMVASLELRNIK-TDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREKQAQLVqglgdTWAGHPRGPPIV
|| . ..||..|...|.| .||.| |.|.|.. .|. |.| |.....|||.|||.| .|.||..||| . .|. .. ..| |..
ywp....gev.tygdftvtllseehlddytvrtlllenldlddltrlvihyhylpwpdhgvPdspedlldfldevrefieell.....sllaldsggpvl
VHCSAGIGRTGTFITLDICISRLedvgTADIRGTVEKIRSQRAY-SIQMPDQYVFCHLALIEY
||||||.|||||.|........| . |. .|...|.|| . ..| |.||.|.. ||.|.
VHCsaGvgRtGtliaaylmllll....gvdleeavkllreqRpgkavqtpsqyrflyeallel
|
subfamily_Cele-PTP-17_pd |
Subfamily Cele-PTP-17 |
550-625 |
1.6e-11 |
38.4 |
In-house |
30-110 (347) |
alignment |
Range on Protein: 550-625
Range on HMM: 30-110/347.0
LHARMRANLTKNRYTDVLCYDHSRVVLAHED-----GDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRMIWEQHC
. .|.||| || | .||||. |. |.. |||| . . .. || || |||.| .|||.|. .
tsvewekslsknrskdvklidatrvvlspeksknsraddvetyinashikfdnaskeyiltqyplpdtvrdfwkmvsvtkv
|
subfamily_Sponge-PTP-2_pd |
Subfamily Sponge-PTP-2 |
550-709 |
2.5e-08 |
27.0 |
In-house |
20-160 (169) |
alignment |
Range on Protein: 550-709
Range on HMM: 20-160/169.0
LHARMRANLTKNRYTDVLCYDHSRVVLAHEDGDEPSDYINAnfvdgykqknayistqgplpktsqdfwRMIWEQHCLVIVMTTRVMERGrvkcgQYWEPT
. | . .| |||| . |. | || | . | |||||| ||||| |||. .. ..|
fmaeltcnetknrpagplapshtrvklqrvmedlgsdyina...........................rmiwetnasvivvlgdtddkn.....nfwpek
EESSLE----FGD-----YHVRTISVECN----EDYMVASLELRNIKTDEIRNVSHWQFTSWPDYGVPSSAMA
|. | .|. .||| |. | | . |. . . . | ..| .....||. ||| | .
edyqlhpavilgewytdslyvrtdkvhantsgveglfevsmvihsydddvteklsllhystwpqngvpqspvh
|
subfamily_Sponge-PTP2_pd |
Subfamily Sponge-PTP2 |
550-709 |
6.9e-08 |
25.5 |
In-house |
19-159 (169) |
alignment |
Range on Protein: 550-709
Range on HMM: 19-159/169.0
LHARMRANLTKNRYTDVLCYDHSRVVLAHEDGDEPSDYINAnfvdgykqknayistqgplpktsqdfwRMIWEQHCLVIVMTTRVMERGrvkcgQYWEPT
. | . .| |||| . |. | || | . | |||||| ||||| |||. .. ..|
fmaeltcnetknrpagplapshtrvklqrvmedlgsdyina...........................rmiwetnasvivvlGdtddkn.....nfwpek
EESSLE----FGD-----YHVRTISVECNEDYM----VASLELRNIKTDEIRNVSHWQFTSWPDYGVPSSAMA
|. | .|. .||| |. | . || . . . | ...| .....||. ||| | .
edyqlhpavilGewytdslyvrtdkvhpntsgveglfevslvihsydddvteqlsllhystwpqngvpqspvh
|
0042113 |
(Phosphotyrosine protein) phosphatases II |
551-804 |
1.5e-85 |
281.8 |
In-house |
3-242 (245) |
alignment |
Range on Protein: 551-804
Range on HMM: 3-242/245.0
HARMRANLTKNRYTDVLCYDHSRVVLAHEDGDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERGRVKCGQYWEPte
.|. .| .||||.|.|.|||.||.| ...||. ||||||..||||.... .| ||||||.| .|||||.||... .||| |. .|.||||| ||| .
vallpenkdknrysdilpydhtrvklspdggdldsdyinasyvdgyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywpl..
ESSLEFGDYHVRTISVECNEDYMVASLELRNIKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREKQAQlvqglgdtwaghPRGPPIVVHCSAGIG
..||..||..|...|.| ..||.| ||. |...|| |.| |.....|||.|||.. .|.||. ||. .|. ... |..||||||.|
gesltygdftvtllseehlddytvrtlevtnlgddesrevihyhylpwpdhgvpdllellldflefvrkalae............dsngpvlVHCsaGvg
RTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEY
||||||........|| .. .. .|...|||| ..|.|.||.|.. ||.|.
RtGtfiaaylmleqlekelgvsleeavkelrsqRpgavqtpsqyrflyeallel
|
subfamily_PTPN12_pd |
Subfamily PTPN12 |
551-805 |
1.4e-72 |
239.1 |
In-house |
34-277 (290) |
alignment |
Range on Protein: 551-805
Range on HMM: 34-277/290.0
HARMRANLTKNRYTDVLCYDHSRVVLAHEDGDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERGRVKCGQYWEPTE
... | .|||| |.| ||.|||.| .....| ||||||||. | ..| .||..||||||| .||||||||.. ..|| |..| |. || .|| .
agekeenvkknrykDilPydksrvelskieeeegsdYinanfikgvegkleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkkCerYWpeeg
ESSLEFGDYHVRTISVEC-NEDYMVASLELRNIktDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREKQAqlvqglgdtwaghPRGPPIVVHCSAGI
|..||||...| ... . ..|... .|.... .| |.| ...|.||| |||||| .|.....||| | |.|||||||.
eeelefgefevtleeekavdddflirtLkveaq..kesrkvyqfhYtaWPDhgvPssaksllelielvrelqe.............sedaPlvvhCsaGv
GRTGTFITLDICISRLEDVGT---ADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEYA
||||| |..|. . |.. . |. | ..| ||| .| .||.. . |..|.
GrtGtiiaidyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavaelv
|
subfamily_PTPN5_RR_pd |
Subfamily PTPN5_RR |
551-806 |
5.6e-71 |
233.8 |
In-house |
22-269 (274) |
alignment |
Range on Protein: 551-806
Range on HMM: 22-269/274.0
HARMRANLTKNRYTDVLCYDHSRVVLAHEDGDEP-SDYINANFVDGYKQ-KNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERGRVKCGQYWEP
. .. . |||||...| ..|||.| .|..... |.|||||.. ||.. ..||..||||||.| .||||||..... ||||.|.. |. . || .|.
eldvfgsqtknryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntvadfWrmiyqeevqvivmltklkeaneqkCavyfPd
TEES--SLEFGDYHVRTISVECNEDYMVASLELRNIKTdeIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREKQAQLVQGLGDTwaghprgppiVVHCS
.|. | ..|| .... .. ..|| | .| |.. . |.| |. .|.||| .| .| ..|.....|.|.. . . |. . |||||
aedyeiserygdveikvekiverndysvrklvlkyler..ersvkhywytdWPdhksPddantlldlvleveesreeenaklapv..........vvhCs
AGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEYAY
||||||| ||. .|.. .|.. .. |. ..| ..| .| .| .|| . | ||..|.
aGiGrtGcfiaisiavrqlreeivvdvlkivcnlrldrGGmvqtseqyelihralclylk
|
subfamily_Nvec-PTP-2_pd |
Subfamily Nvec-PTP-2 |
552-807 |
6.3e-73 |
240.0 |
In-house |
4-244 (250) |
alignment |
Range on Protein: 552-807
Range on HMM: 4-244/250.0
ARMRANLTKNRYTDVLCYDHSRVVLAHEDGDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERGRVkCGQYWePTEE
|. .|. ||||.|.. .|.||||| .|.||. |||||| |..||....|.| |||||..| .|||||..|.. .||| | . | ... . ||| |.|.
akkpqnkeknryadiialdssrvvLekekgdkesdyinasflhgyderkafiatqgPlqatiedfWrmvleeksgtivmLtnLkesekt.yhqyw.Pvek
sSLEFGDYHVRTISVECNEDYMVASLELRNIKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREKQAQLVQGlgdtwaghprgpPIVVHCSAGIGR
. ..|| .| | | ||.. | | . | . | | . .|..||| ||| | |.|..|.||. .| | .. |..|.||||.||
.aekyGdvtvsllskeefadytkrklklskakkaderivrqlhfvvWPdkgvPevatavLellkkvqasqqqagna............PvivqCsaGvgr
TGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEYAYS
.|.||..| . ||. . |.. ....| .| ... .||||.. ..... |
sGafiaidavlerlkkekvvdvfkvikvlrkdrphavesleqyvfvyeiilkalds
|
subfamily_PTPN23_pd |
Subfamily PTPN23 |
552-805 |
3.3e-62 |
204.9 |
In-house |
38-280 (288) |
alignment |
Range on Protein: 552-805
Range on HMM: 38-280/288.0
ARMRANLTKNRYTDVLCYDHSRVVLAhedgDEPSDYINANFVDGYKQK-NAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERGRVKCGQYWEPTE
| . . .|||..|.| |||.||.| .. ||||| || . .| ||.||..|..|||.|..||. |||| . |.|. |. .|| .
aiaklyseknrsrdilPyDhnRvklr....gskDDYinAsfvkdlspgcPdfiatqaPlqstlnDFWlmvyeqkssviVmllskeelgkpkvdrYwPedk
ESSLEFGDYHVRTISVECNEDYMVASLELRNIKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREKQaQLVQGLGDTwaghprgpPIVVHCSAGIG
. . .|||..| ||. | .. |.|. ..|....||| |.||||..|||.| .|.||..|... . || .| |.|||||||.|
getvkfgdlsvtlksvretethvervlkletldadavksvshlqltsWpelGvPasPetllqfldevesay.eavqrkskt........PlvvhCsaGvg
RTGTFITLDICISRLE-DVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEYA
|||.| . . || . | .|| |...| || ...| .|. |. | .|.|
RtgvfalvyaavrelekgnglldiiqvvsrlreqRrfmvqekeqlkfsyeavleaa
|
subfamily_Nvec-PTP-1_pd |
Subfamily Nvec-PTP-1 |
552-803 |
1.5e-53 |
176.4 |
In-house |
2-238 (239) |
alignment |
Range on Protein: 552-803
Range on HMM: 2-238/239.0
ARMRANLTKNRYTDVLCYDHSRVVLAHEDGDEPSDYINANFVDGYKQ-KNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERGRVKCGQYWEpte
|. | | .||||.... |||||||| . | ||||||... | .|||.||| . .| |||||.|... |||| | ..| . || |||
akkrvnkaknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywp...
ESSLEFGDYHVRTISVECNEDYMVASLELRNIKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREkqaqlvqglgDTWaghPRGPPIVVHCSAGIG
.|. .. . .| | ||.. .. . .. | | | ...|| ||| ||| | |.| . .|. . |. | | |.|||||.|
dstskycnlrvtlrktevfadyiirtfvmsqvgqteeryvyqyhftvwpdkgvpqyatavlglrrkitk..........dsl...pgarpwvihcsagvg
RTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIE
|||.|. .| . . . | || |. || .| . .| .|||| |||..|
rtgaflvidamlrqakkqktvdifnyvkairedrphmvqtseqyvfihlavle
|
subfamily_Anemone-PTP-1_pd |
Subfamily Anemone-PTP-1 |
552-803 |
2e-53 |
176.0 |
In-house |
3-239 (239) |
alignment |
Range on Protein: 552-803
Range on HMM: 3-239/239.0
ARMRANLTKNRYTDVLCYDHSRVVLAHEDGDEPSDYINANFVDGYKQ-KNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERGRVKCGQYWEpte
|. | | .||||.... |||||||| . | ||||||... | .|||.||| . .| |||||.|... |||| | ..| . || |||
akkrvnkaknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywp...
ESSLEFGDYHVRTISVECNEDYMVASLELRNIKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREkqaqlvqglgDTWaghPRGPPIVVHCSAGIG
.|. .. . .| | ||.. .. . .. | | | ...|| ||| ||| | |.| . .|. . |. | | |.|||||.|
dstskycnlrvtlrktevfadyiirtfvmsqvgqteeryvyqyhftvwpdkgvpqyatavlglrrkitk..........dsl...pgarpwvihcsagvg
RTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIE
|||.|. .| . . . | || |. || .| . .| .|||| |||..|
rtgaflvidamlrqakkqktvdifnyvkairedrphmvqtseqyvfihlavle
|
subfamily_Urchin-PTP-2_pd |
Subfamily Urchin-PTP-2 |
552-595 |
6.6e-08 |
26.3 |
In-house |
42-85 (440) |
alignment |
Range on Protein: 552-595
Range on HMM: 42-85/440.0
ARMRANLTKNRYTDVLCYDHSRVVLAHEDGDEPSDYINANFVDG
| . | |||| ..|.||||||.| . | |||||| ...|
aslpnnkvknryrnilaydhsrvmleevkgvpdsdyinasying
|
subfamily_Sponge-PTP5_pd |
Subfamily Sponge-PTP5 |
553-807 |
4.4e-50 |
165.2 |
In-house |
29-268 (283) |
alignment |
Range on Protein: 553-807
Range on HMM: 29-268/283.0
RMRANLTKNRYTDVLCYDHSRVVLAHEDGdepsDYINANFVD---GYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERGRVKCGQYWePt
. | .|||. ... .| || | | ||||| |. |||.. || .|.|| .| .|||.|..... ||| |...| |.|| ||| |
sadenkrknrnqeivpadqwrvelksesr....dyinavfipvsksykqdkkyiiaqsPldrtvvdfWkmvfdekitaivmltklqedlrikCsqyW.P.
EESSLEFGDYHVRTISVECNEDYMVASLELRNI-KTDEI-RnVSHWQFTSWPDYGVPSSAMAMLNFlQKVREKQAQlvqglgdtwagHPRGpPIVVHCSA
.. | ..|.. | .. ... | ||. . . ..|.|. | .|| . ....| ||. .| . ...| |||||||.
krGsedyGeftvtlrkettsnsfiikelllrvnssakstll.lahyqvidWleygeqaiinslvkf.nkvislqte...........skkg.PivvhCst
GIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEYAYS
|||||..||.. . . |. .|. .| || .| ||| . | . .| |
giGrtavfiaasasvkdaltesvvdvfavvkimreqrmmavqtldqyklvhelvleqalc
|
subfamily_Cele-PTP-15_pd |
Subfamily Cele-PTP-15 |
553-812 |
1.5e-36 |
120.9 |
In-house |
31-277 (285) |
alignment |
Range on Protein: 553-812
Range on HMM: 31-277/285.0
RMRANLTKNRYTDVLCYDHSRVVLAHEDgdepSDYINANFVD-GYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERGRVKCGQYWEPTEE
|| |||.|| | . .|||| | ||| |... |....||.||||||.| |||.||.... ..| ..| | || |.
ayeanpdlnryadvrcieetrvvlknhd....rdyihaswmrmpgkdqstyittqgplpetlsdfwhmiyqekiayvlmlctlfeggvekcalyypeklg
SSLEFGDYHVRTisVECNEDYMV----ASLELRNIK--TDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREkqaqlVqglgdtwagHPRGPPIVVHC
..|| | . ||.|. . .| . | . . | . | | ||| | | |... . |.. | |. ||.|||
evvkfgkyeitl..teckeeaiagtilnaltvintedasseplymnhvqvpwwpdqlapedarpmielykwvkk.....v.........npkekpicvhc
SAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEYAYSRGMLQ
|||.||| ||. .| . |. . .. | ..|. | ..| |..| .. |.|| |...
sagvgrtatfvgidyatirimenpniemldivremramrfqavqshmqflflyvvlmeyfigegvve
|
subfamily_Cele-PTP-16_pd |
Subfamily Cele-PTP-16 |
553-812 |
4.8e-27 |
89.4 |
In-house |
43-286 (303) |
alignment |
Range on Protein: 553-812
Range on HMM: 43-286/303.0
RMRANLTKNRYTDVLCYDHSRVVLAHedgdepSDYINANFVDGYKQKNAyISTQGPLPKTSQDFWRMIWEQH--CLVIVMTTRVMERgrvKCGQYWEPTE
.. |. |||..||.| |||.| |. | || |.... .|.| | || ||..|. |||.|| ||. |.....| ... |.. | .
qfvknmdknrfvdvicldhskvklsd......ssyihasyleldsskka.iltqlplshtaadfwqmiieqkvkcvlllltdseydk...lggdsvfprn
ESSLEFGDYHVRTI---SVECNEDYMVASLELRNIKTDEIRNVSHwqFTSWPDYGVPSSAMAmlNFLQKVREKQAQLVQglgdtWAghpRGPPIVVHCSA
. |.| . .| || . . . | . | . . | | . .|| .|| . . .|.... . |. | . .. . | | .
qdflkfeersirvgefkrvelgdgwvlkvlsvsngdyksflhvhh..ykawphnsipsdgsp..kfvkqiwqlqsvlrk.....ys...dstptvymsls
GIGRTGTFITLDIC-ISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEYAYSRGMLQ
| ||.||| .. . .| .. . |. .|..| | ...| |. . . | |. |. .
gcgragtfalfetahlslhseqasldlvkclenvrngrlhavqnlsqfsvvytllaehvldngick
|
subfamily_Cele-PTP-4_pd |
Subfamily Cele-PTP-4 |
553-805 |
6.4e-20 |
65.8 |
In-house |
47-285 (302) |
alignment |
Range on Protein: 553-805
Range on HMM: 47-285/302.0
RMRANLTKNRYTDVLCYDHSRVVLAHedgdEPSDYINANFVDGYKQKNAYISTQGPLPKTS---QDFWRMIWEQHCLVIVMTTRVMERGRvKCGQYWEPT
..|| ||. .|| ..|. .| |.. || .|.|| |. . .. | .| | ... ..||||...... .|. . | . ... .
afkknlkknqsedvpildsnlvklea....epdsyvnaskvevPeltrsiilaQlpkvdsedsveeFWrmvfqekivsvvilvgeeelkk.tlselfpkk
EESSLEFGDYHVRTISVECNEDYM-VASLEL--RNIKTDEIRNVSHwqFTSWPDYGVPSSAMAMLNFLQKVREKQAQlvqglGDTwaghprgpPIVVHCS
.. .|.|. | . || |. ..|. .. . || . .| |.. || . .. . .|| .|... .| ..|.
sgdykeygkmfvNnrkVekaeeektryviEvlPegcsnsvlanvyv..ltnWkqkkvpvkyaeliktaakvfakkik.....ade........ntvivSk
AGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEYA
|.|| |.|.|| . ...|.. | .|..|||||. ... .|||. ..||. |
nGaGRagafltlavaveklqkgkepnikeivksiRsqRpravdslkQyvslyialllyi
|
subfamily_Cele-PTP-13_pd |
Subfamily Cele-PTP-13 |
554-805 |
6.7e-41 |
134.8 |
In-house |
34-269 (281) |
alignment |
Range on Protein: 554-805
Range on HMM: 34-269/281.0
MRANLTKNRYTDVLCYDHSRVVLAH-EDGDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERGRVKCGQYWEPTEES
| ||||... | | ||| | . .||| ||.. | || |||| .| |||||||.. ||| ...| | || .|.
qpvnnkknrylnipcldisrvqlkvkmpnknstdyihanyirspflkrgyiltqgpkketradfwrmiwqenttaivmlcqfletnrekcaeyfprnahc
SLEFGDYHVRTISVECNEDYMVASLELRniKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREKQAqlvqglgdtwaghprgpPIVVHCSAGIGRT
|.| . | |. . . |.| | | ..|| . |||. || |. ||. |.|.| . . | |.|||||.||.
clqfdklsvsyedstvnkslvttrlnls..yegetrlithwlwkewpdwqvpessevmlkilrkirarst.................ppvihcsagvgrs
GTFITLDICISRLED-VGTADIRGTVEKIRS-QRAYSIQMPDQYVFCHLALIEYA
||.....|.. . . ||. | ..| || |.| .||.. |...
gtlmaveialqsihshftlpdikqivshlrvtgraasvqtlqqymliwkvlldfg
|
subfamily_Cele-PTP-12_pd |
Subfamily Cele-PTP-12 |
554-641 |
6.9e-16 |
52.6 |
In-house |
31-117 (332) |
alignment |
Range on Protein: 554-641
Range on HMM: 31-117/332.0
MRANLTKNRYTDVLCYDHSRVVLAHEDGDEpsDYINANFVDGYKQKNAYISTQGPLP-KTSQDFWRMIWEQHCLVIVMTTRVMERGRVK
. |. || . |.||||| || .|| . |. ||..|||| .|.||| .| |. .| ||||. |.. .|.. . |. . |
flnnmdmnriphlycfdhsrvelapqdgkd..dfynaswvdgyskksayifaqapfndhteyvfwrmvserkpsmilvfgdidekqkrk
|
subfamily_Sponge-PTP3_pd |
Subfamily Sponge-PTP3 |
554-607 |
1.2e-13 |
45.1 |
In-house |
45-95 (95) |
alignment |
Range on Protein: 554-607
Range on HMM: 45-95/95.0
MRANLTKNRYTDVLCYDHSRVVLAHEdgdEPSDYINANFVDGYKQKNAYISTQG
||. |||. ... || .||||. |||||| ||||| .||.||..||
seanipknrflnifpydatrvvlttk...rdsdyinacfvdgyarkncyiaaqg
|
subfamily_ptpA1_pd |
Subfamily ptpA1 |
555-766 |
7.3e-46 |
151.7 |
In-house |
45-257 (418) |
alignment |
Range on Protein: 555-766
Range on HMM: 45-257/418.0
RANLTKNRYTDVLCYDHSRVVLAHEDGDEPSDYINANFVDGYKQKNaYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERGRVKCGQYWEP---TEE
. | .|||||..| .|.|| | . . | |||||||..|| |. .| ||||||.| |||||.||..| .||| .| | |.|| .|| |.
khntsknrytnilpvnhtrvqlkkiqdkegsdyinanyidgaypkq.fictqgplpntiadfwrmvwenrcriivmlsresencrikcdrywpeqiggeq
SSL------EFGDYHVRTISVECNEDYMVASLELRNIKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREKQAQLVQGlgdtwagHPRGPPIVVHC
|. || | | . | . . . . ..| | |.....|. |||. .| . . ..|. . ..| |.. | ||.|||
fsiygngnevfgtysvelveviqdpereiitrnirltfegetrditqyqyegwpdhnipdhtqpfrqllhsitnrqnqiips.......sdrnvpiivhc
SAGIGRTGTFITLDICISRLE
|||.|||||| | | . .|.
sagvgrtgtfctavimmkkld
|
subfamily_eak_pd |
Subfamily eak |
555-808 |
2.9e-18 |
60.4 |
In-house |
50-308 (332) |
alignment |
Range on Protein: 555-808
Range on HMM: 50-308/332.0
RANLTKNrYTDVLCYDHSRVVLAHEDgDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERGRVKCGQYWEPTEESSL
.. .| ... ||. | |. .. |||| .. . . || | . . ||.|. ||. ||. .| . | .|. |
leavnrn.vvkivpydrylvrltssq.lnrlGyinaslaefsevGrkyiltGiasedkvfafwqmvleqkspaivqlledvelkleksdkyfpdktreel
EFGDYHVRTISVECNEDYMVASLELRniKTDEIRNVSHWQFTSWPDYGVPSS--AMAMLNFLQKVRE-----KQAQLVQGLGDTWAGHPRGPPIVVHCSA
.|| ..| . . .. . . |||. | .| .| |... | .. .| .|. . ...| ...|.. . . | .. ..
kfGildverkefvkrniletrllels..kGnethrvlhykvfGwtettlpkyedflalrkvmkevGvlllivmksallsstlkkyihtppsfapiiqsar
GIGRTGTFITLDICISRLEDVGT--ADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEYAYSR
| |.|.|. .|. | ... . . . |..|.| .|. . |. | . ....| |
GsaraGvfvvidllirlidnkkknlysvedlilkvkskrihsvlvalqhsfiyeivldyllrr
|
subfamily_Sponge-PTP1_pd |
Subfamily Sponge-PTP1 |
556-812 |
3.2e-46 |
152.5 |
In-house |
32-264 (267) |
alignment |
Range on Protein: 556-812
Range on HMM: 32-264/267.0
ANLTKNRYTDVLCYDHSRVVLAHEDGDepsdYINANFVDGYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERgrvKCGQYWEPTEESSLE
| .||. |.| ||..||.| .. . |||| .|.|||.|||.| ||.|| .| ||. .| .|.. |||. |.| . . ..| | . .
knqernrlddnlpyddtrvilrtkeee....yinasyvegyktknafivtqdplkntitdfltvihdqkvpvivlltkvftd...nirlfwPPkmgqakk
FGDYHVRTISVECNEDYMVASLELRnIKTDEIRNVSHWQFTSWpdyGVPSSAMAMLNFLQKVREKQaQLVQGlgdtwaghprGPPIVVHCSAGIGRTGTF
. | | . ..|| . .|||. .| . .||. . . | . . |. | . |. || .| ..|.||.||.|.||.|||
yqdltvehslekeendyqiitlelk.fknesahnvtlyyykkw...nintnnkpylkplfgilakn.qleng..........nrPlvvacsdGvGrsGtf
ITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEYAysRGMLQ
...| . |. |..|| . |||||| .. ..|...| | ||| .|.|.
lvidsqleraktegvsdifdflrkirsqriglvdtkeryiyihellaeya..egrlk
|
subfamily_Cele-PTP-10_pd |
Subfamily Cele-PTP-10 |
556-805 |
3.5e-42 |
139.1 |
In-house |
54-289 (305) |
alignment |
Range on Protein: 556-805
Range on HMM: 54-289/305.0
ANLTKNRYTDVLCYDHSRVVLAHEDgdePSDYINANFVDGYK-QKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERGRVKCGQYWEPTEESSL
. |||||.|| | |.| | |.. ||||| ||.| .. .| .|||| .| ..|| |. ... ||| . .| |..|| ||| . |
iaitknryqdvpcqdqsavkldkps...psdyihanyvgcpmipekrficaqgpldqtidefwwmviqnkveqivmlcktvelgklkcaqywpaaqgekl
EFG-DYHVRTIS----VECNEDYMVASLELRnIKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREKQAqlvqglgdtwaghprgpPIVVHCSAGI
|. | .| .| . . .. |.| |. | | |.| ||| ||| .. |..| .| . ||||||||||
elksgivvenvsgskpmerdaeiqitllnlt.ysgdqkmsvrhlqwtewpdrgvppckltslellsairgskv.................pivvhcsagi
GRTGTFITLDICISRL-EDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEYA
||||| .... . .. |. . | .| |||.||| ||.| | ...|
grtgtivaieyilekiaenkpcppmpelvkalrdqrafsiqndvqylfihrvmlnyf
|
Y_phosphatase |
Protein-tyrosine phosphatase |
557-802 |
9.2e-87 |
285.7 |
Pfam-A |
1-234 (235) |
alignment |
Range on Protein: 557-802
Range on HMM: 1-234/235.0
NLTKNRYTDVLCYDHSRVVLahEDGDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERGRVKCGQYWEPTEESSLEF
|..||||.|.|.||..|| | .. ..||||||||.|.|||.|...| |||||..| .|||||.|.... |||| |...|.||.|| |||. .|| ||..
nkkknRykdilpydktrvkl..kgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeeslty
GDYHVRTI-SVE-CNEDYMVASLELRNIKTD-EIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREKQaqlvqglgdtwagHPRGPPIVVHCSAGIGRTG
||..|.. ... ...|.. |||.. |.. | | |.....|.|||.|||.|. ..|....||.... ... |.|||||||.||||
gdikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkveksk.............eaksgpvvVhCsaGvgRtg
TFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALI
||..|||....||. .. |. .|...|.||. ..| .||.|.. |..
tfvaldilleqleaeeevdvlqivkelRkqRpgmvqsleqYiflykail
|
Y_phosphatase |
Protein-tyrosine phosphatase |
557-802 |
9.2e-87 |
285.7 |
In-house |
1-234 (235) |
alignment |
Range on Protein: 557-802
Range on HMM: 1-234/235.0
NLTKNRYTDVLCYDHSRVVLahEDGDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERGRVKCGQYWEPTEESSLEF
|..||||.|.|.||..|| | .. ..||||||||.|.|||.|...| |||||..| .|||||.|.... |||| |...|.||.|| |||. .|| ||..
nkkknRykdilpydktrvkl..kgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeeslty
GDYHVRTI-SVE-CNEDYMVASLELRNIKTD-EIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREKQaqlvqglgdtwagHPRGPPIVVHCSAGIGRTG
||..|.. ... ...|.. |||.. |.. | | |.....|.|||.|||.|. ..|....||.... ... |.|||||||.||||
gdikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkveksk.............eaksgpvvVhCsaGvgRtg
TFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALI
||..|||....||. .. |. .|...|.||. ..| .||.|.. |..
tfvaldilleqleaeeevdvlqivkelRkqRpgmvqsleqYiflykail
|
subfamily_Choan-PTP-2_pd |
Subfamily Choan-PTP-2 |
557-807 |
1.5e-68 |
225.8 |
In-house |
20-266 (270) |
alignment |
Range on Protein: 557-807
Range on HMM: 20-266/270.0
NLTKNRYTDVLCYDHSRVVLAHEDGDEPSDYINANFVDGYKQ-KNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERGRVKCGQYWEPTEES--S
. . |||.|.| ..||.|.... |. . |||||.| |... |..||...|||| | ..|||||||.. ||||| ..|.|| || .|| . .. .
gkklnRyadiLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpaepkekvk
LEFGDYHVRTISVECNEDYMVASLELRniKTDEIRNVSHWQFTSWPDYGVPSSAM------AMLNFLQKVREKQAQLVQGlgdtwaghprgPPIVVHCSA
||.|. .|...| | .| |.. |.|. .. |.|.. |.....||| |||... .|. |..||. . .| .. |..|||||
ledgkikvlalseekeegyiltrlrle..ekgeerrlvHfwyntWpdhgvpreedsslstdqllkmlravrrsekeldka...........ePllvHcsa
GIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEYAYS
|.|||||.|.|||.. || . .|. .|..| .| .| |.|| | . |..|||
GvgRtGtlialDiavrlLeetkkvdvlaiieelRkdRmalvqhpeqyeflykavveyaer
|
subfamily_Anemone-PTP-4_pd |
Subfamily Anemone-PTP-4 |
557-803 |
1.2e-56 |
186.6 |
In-house |
3-237 (237) |
alignment |
Range on Protein: 557-803
Range on HMM: 3-237/237.0
NLTKNRYTDVLCYDHSRVVLAHEDGDepSDYINANFVDGYKQ-KNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERGRVKCGQYWEPTEEsSLE
| |||| .. .|||||||| .. ||||||....|. . ||..|||| . .|||.|.|...| |||| | ..|. ..|| .|| |..
nkiknrygnivaydhsrvvlkgagsg..sdyinatylkgfdgtpkkyiaaqgplesscddfwqmvwqekcsvivmltgliegnelkchkywpstdq.paa
FGDYHVRTISVECNEDYMVASLELR-NIKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREKQAQLvqglgdtwaghPRGPPIVVHCSAGIGRTGT
.| . | | || | || | ... |.| . .||||||| ||| . |.| | ... .. . .. | ..|||||.||||
ygvltvslkkkeefsdytvrslllskrltlkevrlihqyqftswpdrgvpqqtaallrfrkniinrsphv...........sesgpwiihcsagvgrtgi
FITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIE
|. .| . . .. || | | .| | || ||||| | ...|
flvidamlrqakekkvvdiynyvysieedrpyiiqtkdqyvfihqtile
|
0041856 |
(Phosphotyrosine protein) phosphatases II |
557-808 |
2.1e-52 |
172.7 |
In-house |
1-174 (182) |
alignment |
Range on Protein: 557-808
Range on HMM: 1-174/182.0
NLTKNRYTDVLCYDHSRvvlahedgdePSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTrvmergrvkCGQYWEpteesslef
||.||||.|.|.||||| ..||||||...|. . .| |||||..| ||.||..|... .||. | . .||
nldknrysdilpydhsr..........dldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlt.........eelywp.........
gdyhvrtisvecnedymvaslelrnikTDEIRNVSHWQFTSWPDYGVPSsAMAMLNFLQKVREkqaqlvqglgdtwaghpRGPPIVVHCSAGIGRTGTFI
... |.. ......|||.|||. .|.|...|.| .| |..||||||.|||||..
...........................ellerlgiqylylpwpDhgvpd.ldelldfieevle.................eggpvlVHCsaGvgRtgtlv
TLDICISRledvgTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEYAYSR
....... ... .|. .||.| ....|.||.|..||| |. . .
aaylmkkl.....gvsleeavklvrsrRpgmvitpnqyfflqlallellllk
|
subfamily_Sponge-PTP6_pd |
Subfamily Sponge-PTP6 |
557-804 |
5.8e-51 |
168.3 |
In-house |
48-278 (439) |
alignment |
Range on Protein: 557-804
Range on HMM: 48-278/439.0
NLTKNRYTDVLCYDHSRVVLAHEDGDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERGRvkcgqYWePTEESsLEF
. ||||| || .||.||.| | | |||||...|| ... ||.|||| .|..||||...|... ||| | ..| . || |... .
dqtknrykdvgafdhtrvtlqeipgvphshyinanyikGyyddklyiatqgpkkettddfwrlviekktvtivmltnlvesyk.....yw.psdae.vcy
GDYHVRTISVECNEDYMVASLELRNI--KTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREKQAQlvQGLGdtwaghprgpPIVVHCSAGIGRTGT
|| ||. .|.. . . | .|. | | ......||| ||. | .|.||. . . . . | |.|||||||.|||||
gdiavrvdrnielpnyvirgfkvfnerdttekertvlqfhyiawpdknvpaqashvldflrainsandk..eeyg..........pvvvhcsagvGrtGt
FITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEY
|.|||.. .| ||.| |. .| || .| |||| . |..|
iialdialeqlklenkvdikgivkvlrkqrkqmvqalcqyvfiynavled
|
subfamily_Fungi-PTP1_pd |
Subfamily Fungi-PTP1 |
558-650 |
3.4e-24 |
80.2 |
In-house |
48-154 (350) |
alignment |
Range on Protein: 558-650
Range on HMM: 48-154/350.0
LTKNRYTDVLCYDHSRVVLA--------HEDGDEPSDYINANFVDGY----KQKNA--YISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERGRVKCG
.||||...| |.|||| | . ...||||||.. ... ||.||.|||.| .||...| . . ||.. | .| .. ||
faknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvelnlekcy
QYWEPTE
.||. .
rYWqegs
|
subfamily_Fungi-PTP2_pd |
Subfamily Fungi-PTP2 |
558-650 |
3.3e-15 |
50.3 |
In-house |
49-157 (349) |
alignment |
Range on Protein: 558-650
Range on HMM: 49-157/349.0
LTKNRYTDVLCYDHSRVVLAHE--------------DGDEPSDYINANFVDG--YKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERGRVK
.|||| |.| |.||||.| . |. . ||||||.. .. .. ||.|| ||| | .||...| . ... . | . |
faknrykdilPyehsrvklkkslksskvikastsesdsgklddyinanylkltrisvekkyiatqaPlPstvddfykvillngvklvlsLnddkelslek
CGQYWEPTE
| .||. .
cdiywqels
|
subfamily_CG42327_pd |
Subfamily CG42327 |
559-720 |
3.8e-36 |
119.3 |
In-house |
30-193 (319) |
alignment |
Range on Protein: 559-720
Range on HMM: 30-193/319.0
TKNRYTDVLCYDHSRVVLAHEDGDEPSDYINANFVDGYKQ-KNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERGRVKCGQYWEPTE--ESSLE
|.|. .|. ..|||| . |. . |..|..| ||.. .| ||..| .| ..| ||||..||| ||| | . | | .| .|. . | ..
dksrvinvvPlPetrvvlqrigdddkdeyldasyvrGyddapnsyiaaqvsledsssdfwrtvweqqsrvivqltdlselGikvcaeylPtketldntsl
FGDYHVRTISVECNEDYMVASLELRNIKTDEIRNVSHWQFtSWPDYGVPSSAMAMLNFLQKVREK
.||. | | .. |....| |.... .| |...|. . |.. .||.. |.. | .||.
yGdilvtlkgrevkdryaistlllkrvdkeesrelthywy.kwleaevPaeeaaliamllevrss
|
subfamily_Cele-PTP-19_pd |
Subfamily Cele-PTP-19 |
559-799 |
5.8e-32 |
105.6 |
In-house |
52-275 (301) |
alignment |
Range on Protein: 559-799
Range on HMM: 52-275/301.0
TKNRYTDVLCYDHSRVVLAhEDGDEPSdyINANFVDGYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERGRVKCGQYWEPTEESSLEFGD
|.|| | | .. | . .|| | ||... . . .|.|||||..||.||| |. . ||| .. .|. || .| . ...|. |
dkhryptvPckPstavevi.vdGkrvP..ihanwiptsGhphrfiatqgPlkntsedfwamlvqydvekivmlgqkvekleekceeylpvkisekldigr
YHVRTISVEC--NEDYMVASLELRNI-KTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREKQAqlvqglgdtwaghprgpPIVVHCSAGIGRTGTF
..... . | |.. . .||... . . | | |.|...|.|.||| | . . .... |.. . ||||||||||||. .|
fkikiknkelilnkkiskrtlevedstgkfatrtvthyqysewtdrgvPkshaelfdlmelvkksek.................PivvhcsaGiGrsvaf
ITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHL
|. .. ...| | .. .....| .| ..|. | . |
igteylareveadptieltealkhlrehrwngvqtnsqlywmtl
|
subfamily_Cele-PTP-1_pd |
Subfamily Cele-PTP-1 |
560-802 |
5.2e-19 |
63.5 |
In-house |
22-256 (290) |
alignment |
Range on Protein: 560-802
Range on HMM: 22-256/290.0
KNRYTDVLCyDHSRVVLAHEDGDEPSDYINANFVDgYKQKNAYISTQGPLPKT-------SQDFWRMIWEQHCLVIVMTTRVMERGRV----KCGQYWEP
..|.. | ..|||| .||| ||.| . . . | || |. |. ..|| |. . . .||. ..|. . | .|
dqRlevpLv.eatrvvLkgygkrfnddyiHAnrvt.cpnglrliltqsPqekitekrnStiekfwwmakqEkvkqvVmlcefeeksantslfaCakYvpe
TEESSLEFGDYHVRTISVECNEDYMVASLELRNIKTDEIrNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREKQAqlvqglgdtwaghprgpPIVVHCSAG
... .| |.. |. | | ..| . |... . | | | .. .| . |. . .|. .|||. ... |..||| |
svgeelkfkgltvkCkskekeddvetRelvvkfddeeef.tvtHsllkgWnklnvqedtktllsliqkvkaskt.................pvivHcvdG
IGRTGTFITLDICISRLE-DVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALI
| | .. .... . | .. ....|.||| |. . .. | ...
iSrsAalaaiilgyQkiaetsgsvkledvlkalrkqralaitsalelafvdagiv
|
subfamily_Sponge-PTP-4_pd |
Subfamily Sponge-PTP-4 |
567-702 |
5.8e-11 |
36.8 |
In-house |
3-125 (130) |
alignment |
Range on Protein: 567-702
Range on HMM: 3-125/130.0
LCYDHSRVVlahedgdePSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERgrvkcGQYWEPTEesSLEFGDYHVRTISV
| .. ||. .||||.|| . . |. || || .|| |||.|. |.. |.|. | | .|| .| ||. . .. .
lefevsrlq........gntyinasfvGllgrtaeylltqhpladtsmdfwkmmleryvnvlvvlgsveee.....deywpdse..Plewyeediivtlt
ECNE-DYMVASlELrNIKTDEIR---NVSHWQFTSWPDYG
. .| ... || .| .|. | .. .. .| . || |
drdefknikas.nl.eiesdlneshqaltmfqisnwpsdg
|
0044763 |
(Phosphotyrosine protein) phosphatases II |
568-803 |
6.2e-33 |
109.3 |
In-house |
1-169 (178) |
alignment |
Range on Protein: 568-803
Range on HMM: 1-169/178.0
CYDHSRVVLAHEDGDEPSDYINANFVDGYkqknAYISTQGPlpktsQDFWRMIWEQHCLVIVMTTRVMERGRVKCGQYWEPTEEsslefgdyhvrtisve
..|..||.| . | | ||||||...... |.....| .|......|... .||. | .|.|..|| .|| ..
pldrtrvllsnleglersdyinaseilpg....lylgslpp.....addlellkelgithivnlteelelgflkcdpywpeeag................
cnedymvaslelrniktdeirnvSHWQFTSWPDYGVPSSAMAMLNFLQKVREKQaqlvqglgdtwagHPRGPPIVVHCSAGIGRTGTFITLDICISRled
..... .||.|||.. .|.|.. ..| . ...| |..||||||.||.||.. .......
.......................iqylhipipDhgvpdllehflefvefieeal.............dekggpvlVHCsaGvgRsgtlvaaylmkkl...
vgTADIRGTVEKIRSQRAySIQMPDQYVFCHLALIE
.. .| .|..| .. |.|. .... .
..glsleeaielvrerRp.ivpnpgqlrqLyefelr
|
0046846 |
(Phosphotyrosine protein) phosphatases II |
579-804 |
7.5e-41 |
135.1 |
In-house |
6-172 (176) |
alignment |
Range on Protein: 579-804
Range on HMM: 6-172/176.0
EDGDEPSDYINANFVDGYKqknaYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERGRVKCGQYWEPTEESSLefgdyhvrtisvecnedymvasle
|...||||||...|.. .| ||||||.| .||..|..|... ..|. | .| ||.|| .||. |. ..
lgldldldyinanlilgsr....piatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpeleklgi........................
lrniktdeirnvsHWQFTSWPDYGVPSSaMAMLNFLQKVREKQaqlvqglgdtwaghPRGPPIVVHCSAGIGRTGTFITLDICISRledvGTADIRGTVE
..... |||.|||.. ..|..|. .|| . .| |..||||||||||||.. ....... .. ...
.............qylhlpwpDhgvpdl.elllellefireal..............keggpvlVHCsaGigRtgtlvaayllele....kglsveeala
KIRSQRA-YSIQMPDQYVFCHLALIEY
..|.|| ...| |.|| |.. .. ..
lvreqRplgavqtpeQyrflyefelll
|
0043147 |
(Phosphotyrosine protein) phosphatases II |
581-798 |
3.5e-44 |
145.9 |
In-house |
1-154 (172) |
alignment |
Range on Protein: 581-798
Range on HMM: 1-154/172.0
GDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVmergrvkcgqywepteesslefgdyhvrtisvecnedymvaslelR
|||.||||||...|.| . .| |||||. | |||||..|... .||. |.
gdegsdyinasyldlyyipdrfiatqgplrntladfwrmlkelgithivnltel.............................................l
NIKTDEIRNVSHWQFTSWPDYGVPsSAMAMLNFLQKVRE--KQAQlvqglgdtwaghprGPPIVVHCSAGIGRTGTFITLDICIsrledvGTADIRGTVE
...... |.. ......|||.||| .. .|.||. ..| . . | |..||||||.|||||.. ..... .. .|.
ydpellerlgiqylylpwpDhgvp.llellleflefidellalsp..............ggpvlVHCsaGvgRtgtlvaaylml......lglsleeava
KIRSQRAYSIQMPDQYVFCH
.|..| ...| |.|| |..
lvrekRpgavqnpsqyrfly
|
0051082 |
(Phosphotyrosine protein) phosphatases II |
584-802 |
2.9e-34 |
113.2 |
In-house |
2-150 (151) |
alignment |
Range on Protein: 584-802
Range on HMM: 2-150/151.0
PSDYINANFVDGYkqknaYISTQGPLPktsqDFWRMIWEQHCLVIVMTTRVMERGrvKCGQYWEPTEesslefgdyhvrtisvecnedymvaslelrnik
|||||...|.|. .. ..|||. ||.....|... .||. . .||| .| .|.. ..
lsdyinfsyvtgg.....lyrsggpla....dflellkelgiktivnlrseeerg..ycpeylpelg.................................
tdeiRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREkqaqlvqglgdtwaghPRGPPIVVHCSAGIGRTGTFITLDICISRledvgtADIRGTVEKIRSQ
..| |.....|||.|.| | |.|.||..... ... |..||||||.|||||.. |.... . .. ..| .|..
....ievlhipildwpdpglplsfdavleflellld................kkngpvlvHCsaGkgRTGtlvalylmllg......vsleealeeyrlk
RAYSIQMPDQYVFCHLALI
| ...| ..|..|...||.
rpgvvqpnqqflfqlfall
|
0051429 |
(Phosphotyrosine protein) phosphatases II |
585-807 |
8.3e-53 |
175.0 |
In-house |
4-227 (272) |
alignment |
Range on Protein: 585-807
Range on HMM: 4-227/272.0
SDYINANFVDGYKQ---KNAYISTQGPLPKTSQDFWRMiWEQHCLVIVMTTRVMERGRVKCGQYWE----------PTEESSLEFGDYHVRTISVECNED
|.||||..|.|| . ..... ..|||| | .||||. .|... .||. ....||||.|| .||. .... . ..|...|...|.|. .|
sgyiNardvggygrvvkpgrlyrsggplpltaadfwrl.kelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseellld
YMVASLELRNI-KTDEIRNVSHWQFTSWPDYGVPSSAmaMLNFLQKVREkqaqlvqglgdtwaghprGPPIVVHCSAGIGRTGTFITLDICISRLEDVGT
|.. |.|... ...|.| | |...|.|||.|||..| .|..|. ... | |..||||||..||||.. |.... ....
yilrellltlllsagearevmhlhytdwpdhgvpqea..llellellld..................ggpvlvHCsaGkdRTGtvvallllllgvsleti
AD--------IRGTVEKIRSQRAYSIQMPDQYVFCHLALIEYAYS
.| ....||..|.||....| ..||.|.. ||.|...|
vddYlltnlyleeaveelraqrpgavqteeqylflyeallellrs
|
0036282 |
(Phosphotyrosine protein) phosphatases II |
585-798 |
3.6e-46 |
152.4 |
In-house |
2-163 (174) |
alignment |
Range on Protein: 585-798
Range on HMM: 2-163/174.0
SDYINANFVDGYKQKNAYISTQGPLPktsqdFWRMIWEQHCLVIVMTTRVMERGRVKCGQYWEPteesslefgdyhvrtisvecnedymvaslelrnIKT
||||||...|.. . .| .||||. ||.|..|... ..|| .. .|.|..|| .|| ..
sdyinaspldlsyitprliagqgpla.....fwemlkelgittvvmlleekelglykcinywpe.................................lre
DEIRNVSHWQFTSWPDYGVPSSAMaMLNFLQKVREKQAQlvqglgdtwaghPRGPPIVVHCSAGIGRTGTFITLDICISRLEdVGTADIRGTVEKIRSQR
|. |.. ..... |||.|||.... .|.|.. |.| ... ..| |..||||||.|||||.. ..... .|. .. |. .| ..|.||
dlerlgiqylylpwpDhgvpdlsi.llefvkfveealse............dpggpvlVHCsaGvgRtGtlvaaylmlrgll.eslvdaldlvrelRlqr
AYSIQMPDQYVFCH
...|.|.|| |..
pgmvqtpsQyrfly
|
subfamily_Sponge-PTP4_pd |
Subfamily Sponge-PTP4 |
587-702 |
3.9e-11 |
37.0 |
In-house |
124-234 (244) |
alignment |
Range on Protein: 587-702
Range on HMM: 124-234/244.0
YINANFVDGYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERgrvkcGQYWEPTEEssLEFGDYH--VRTISVECNEDYMVASLELRNIKT
|||| || . || || || || |||.|. |.| |.|. | | .|| .| ||. . | . . . ||.
yinasfvgclgrtaeyiltqhpladtsmdfwkmmlerhvnvlvvlgsveee.....deywpdsep..lewyeeditvtltdrdefknikasnleiesdmn
DEIRNVSHWQFTSWPDYG
. . .. .| . || |
eshqaltmfqisnwpsdg
|
0049260 |
(Phosphotyrosine protein) phosphatases II |
592-798 |
3.5e-39 |
129.3 |
In-house |
1-143 (152) |
alignment |
Range on Protein: 592-798
Range on HMM: 1-143/152.0
FVDGYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERGRVKCGQYWepteesslefgdyhvrtisvecnedymvaslelrniktdeirnvs
|.|||......| ||||.| | |||||..|... .||| |. .|.|..|| ||.
fidgyampfefiatqgpgpntladfwrmlkelgittivmltellelgklkceqyi.............................................
HWQFTSWPDYGVPSSAMAMLNFLQKVREKqaQ-LvQ-GlgdtwaghprgpPIVVHCSAGIGRTGTFITLDICIsrledvGTADIRGTVEKIRSQRAYSIQ
..... |||.|||.... .| .|. ... . . | |..||||||.|||||.. ..... .. .|. .|..| ....
qylhlpwpDhgvpdlsqlllflllfiekl..ald.kgg............pvlVHCsaGvgRtgtlvaaylml......lgvsleeavalvrekRpgavp
MPDQYVFCH
|.|. |..
npgqlrfly
|
subfamily_Urchin-PTP-2_pd |
Subfamily Urchin-PTP-2 |
593-688 |
7.2e-12 |
39.3 |
In-house |
229-321 (440) |
alignment |
Range on Protein: 593-688
Range on HMM: 229-321/440.0
VDGYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERgrvKCGQYWePTEESSLEFGDYHVRTISVECNEDYMVASLELRNI-KTDEIR
..|| .|||.|.|| || | ||||.. . . |.| .. .. | || | . |. || . | | . | .|||. . |||
fegyskknafiatqmpldstvldfwrlvhdyristiimlnqlndk...tcsiyw.pvntrsvtfgpftvghkgsenmnrvkvrtlelkykeevheir
|
subfamily_Cele-PTP-7_pd |
Subfamily Cele-PTP-7 |
594-799 |
6.3e-19 |
62.5 |
In-house |
84-282 (302) |
alignment |
Range on Protein: 594-799
Range on HMM: 84-282/302.0
DGYKQKNAyISTQG--PLPKTSQDFWRMIWEQHCLVIVMTTRVMERGRVKCGQYWEPTEESSLEFGDYHVRTISVECN-------EDYMVASLELRNIKT
|| ..|. .| . | .| . .| .| . . ..| . ..| . || .|. . |.|| | |.|.||. . ..... ..|..| |.
dGtekkek.vskkpivpkkstlekhwalieqynvaivvqlcsfvedeekkcaeyysdkvggelkfgrytvktvsvktdleeftdkksfklytveiknekk
DE--IRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVrEKQAQLvqglgdtwaghprgppIVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRS
. . |. .|..|||.| | | . |. |. | . ..||||||.|||||.... | ..|. | .|.
kkkvkktvdilafsawpdhGapkeaytaldilkfc.esykkn................vlvhcsaGvGrtGtlvaikyGiqlcskkkvtdllsivlpvrq
QRAYSIQMPDQYVFCHL
| ..| .| .. |
cryGavqdeqqliylll
|
subfamily_Anemone-PTP-3_pd |
Subfamily Anemone-PTP-3 |
597-794 |
3.1e-25 |
83.5 |
In-house |
2-193 (199) |
alignment |
Range on Protein: 597-794
Range on HMM: 2-193/199.0
KQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERGRVKCGQYWEPTEESSLEFGDYHVRTISVECNEDYMVASLELRNIKTD--EIRNVSHWQ
| . ||.|| || .| |||.|.|| ||| . || || .. ..| | | .. .. || ...| | | | |..||.|
kgqrryiatqhplretmadfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyq
FTSWPDYGVPSSAMaMLNFLQKVREKQAQLVQGlgdtwaghpRGPPIVVHCSAGIGRTGTFITLDICISRLEDVGTA--DIRGTVEKIRSQRAYSIQMPD
|||| . | |. .. |. || . | . |..|||| | | || |..||| . |. |. |. ..| | | .
ftswkekttpnval.fvgfvvasrevskkyeqe.........kdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiisslq
QY
.|
hy
|
subfamily_hpo-7_pd |
Subfamily hpo-7 |
597-721 |
2.1e-10 |
34.9 |
In-house |
35-155 (263) |
alignment |
Range on Protein: 597-721
Range on HMM: 35-155/263.0
KQKNAYIStqgpLPKTSQDFWRMIWEQHCLVIVMTTRVMERGRVKCGQYWEPTEESSLEFGDYHVRTISVECneDYMVASLELRNIKT--DEIRNVSHWQ
|.|| |. | .| . |...| . |.|| . | |..|| .|. . . . . | | | | .. .||| .. ....| |..
krknlysl....lvqtidkfyqtivqtktevvvmLcDfneegvekcssyfPlekdekqklanvnvcttkvqs..dvllktlellstlgeKkkthtvkhys
FTSWPDYGVPSSAMAMLNFLQKVREKQ
.. |.. | | .|| |. .|. .
ykgWiekndpelareilnilkvarnsk
|
subfamily_Cele-PTP-9_pd |
Subfamily Cele-PTP-9 |
597-725 |
3.3e-10 |
34.5 |
In-house |
32-153 (255) |
alignment |
Range on Protein: 597-725
Range on HMM: 32-153/255.0
KQKNAYIStqgplpkTSQDFWRMIWEQHCLVIVMTTRVMERGRVKCGQYWEPTEESSLEFGDYHVRTISveCNEDYMVASLELRNIK--TDEIRNVSHWQ
|.|| |. | . |...| . |.|| . | |..|| .|. . | . | | | | .. ||. . ..| |..
krknlysl.......tvdkfyqtivqtktevvvmlcdfaeegvekcssyfplekdeklkladvnvtttk..ssadvvlrtleitstlgekkkthtvkhys
FTSWPDYGVPSSAMAMLNFLQKVREKQAQLV
.. |.. | | .|| |. ||. .. .|
ykGWieknaPelareilnilkvvrdsksvvv
|
subfamily_Nvec-PTP-3_pd |
Subfamily Nvec-PTP-3 |
599-794 |
4.2e-25 |
83.1 |
In-house |
3-192 (198) |
alignment |
Range on Protein: 599-794
Range on HMM: 3-192/198.0
KNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERGRVKCGQYWEPTEESSLEFGDYHVRTISVECNEDYMVASLELRNIKTD--EIRNVSHWQFT
. ||.|| || .| |||.|.|| ||| . || || .. ..| | | .. .. || ...| | | | |..||.|||
qrryiatqhplretladfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyqft
SWPDYGVPSSAMaMLNFLQKVREKQAQLVQGlgdtwaghpRGPPIVVHCSAGIGRTGTFITLDICISRLEDVGTA--DIRGTVEKIRSQRAYSIQMPDQY
|| . | |. .. |. || . | . |..|||| | | || |..||| . |. |. |. ..| | | ..|
swkekttpnval.fvgfvvasrevskkyeqe.........kdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiisslqhy
|
0048179 |
(Phosphotyrosine protein) phosphatases II |
660-799 |
1.8e-23 |
78.3 |
In-house |
32-139 (144) |
alignment |
Range on Protein: 660-799
Range on HMM: 32-139/144.0
HVRTISVECnedymvaslelrnIKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREKqaqlvqglgdtwagHPRGPPIVVHCSAGIGRTGTFITLD
.| ... |. .....|.. ......|||.|||... .|.||. ..| ...| |..||||||.|||||.....
tvinlteey.............epefleregiqylhlpwpDhgvpdllellleflefieea..............leeggpvlVHCsaGvgRtgtlvaay
ICIsrledVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHL
... . .. ... .||.| .... |.|. |...
lmk.....klglsleealalvrsrrpgavpnpgqlrfLle
|
0048076 |
(Phosphotyrosine protein) phosphatases II |
666-803 |
5.2e-25 |
83.2 |
In-house |
36-141 (145) |
alignment |
Range on Protein: 666-803
Range on HMM: 36-141/145.0
VecnedymvaslelRNIKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREKQAQlvqglgdtwaghprGPPIVVHCSAGIGRTGTFITLDICISrl
. . .... |.. ......|||.|||... .|.||. ..| ... | |..||||||.|||||.. ......
l.............tselellerlgiqylylpwpDhgvpdllellleflefieealke..............ggpvlVHCsaGvgRtgtlvaaylmll..
edvGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIE
.. ..|..|||| .... |.|. |..... |
...lgvsleealelvrsqrpgavpnpgqlrflyefele
|
subfamily_Urchin-PTP-2_pd |
Subfamily Urchin-PTP-2 |
671-805 |
1.5e-15 |
51.4 |
In-house |
76-194 (440) |
alignment |
Range on Protein: 671-805
Range on HMM: 76-194/440.0
DYMVASLelrnIKTDEIRNVSHWQFTSWPDYGVPSSAMAMLNFLQKVREKQAQLVQGlgdtwaghprgpPIVVHCSAGIGRTGTFITLDICISRLEDVGT
||. || |. | | . .... .||| ||| | .|...| | | | . .| |..|||||| |||| |..| . .
dyinasy....ingiesrtlkqyhyqgwpdkgvpkfagpvlkmiqdvnesqekagng............pllvhcsagagrtgviiavdsilreakrsdq
ADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEYA
|| .. .|..| .| |.||.| | |..|
idifsfinsmrnnrpqmvqtpeqyafvheavlegl
|
subfamily_Fungi-PTP2_pd |
Subfamily Fungi-PTP2 |
683-766 |
3.5e-11 |
37.0 |
In-house |
213-293 (349) |
alignment |
Range on Protein: 683-766
Range on HMM: 213-293/349.0
KTDEIRNVSHWQFTSWPDYgvpSSAMAMLNFLQKVREKQAQLVQGLGDTWAGHPRGPPIVVHCSAGIGRTGTFITLDICISRLE
.... . |. |.| | . .|| . |. . . . . . ....|||||| ||||...|||. .| ||
avekPyellqlqvknwldl...slllnPisilqalevkndliddlfarlyldtdqlstllvhcsaGcGrtGvlvtldlllsile
|
subfamily_Fungi-PTP1_pd |
Subfamily Fungi-PTP1 |
686-804 |
3.8e-16 |
53.7 |
In-house |
214-343 (350) |
alignment |
Range on Protein: 686-804
Range on HMM: 214-343/350.0
EIRnVSHWQFTSWPDYGVPSSAMAMLNFLQkvrEKQAQLVQGLGDTWAGHPRGPPIVVHCSAGIGRTGTFITLDICIS---RLEDVG-----------TA
| . |. |.| .. .|. |. |. . . .. |..||.||||||.|||||..||| .| || . |
Pyv.vyqlqvknWkDlslllnPesilqale...vkndliddlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaaktr
D-IRGTVEKIRSQRAYSIQMPDQYVFCHLALIEY
| | .| ..|.|| .| ||..|.. || |
DlisiivnelrkqrismvqnldqfifiYeallfy
|
PTPc_DSPc_SM00012 |
|
690-802 |
7e-33 |
108.3 |
In-house |
2-104 (105) |
alignment |
Range on Protein: 690-802
Range on HMM: 2-104/105.0
VSHWQFTSWPDYGVPSSAMAMLNFLQKVREKQAQLVQglgdtwaghprGPPIVVHCSAGIGRTGTFITLDICISRLEDV-GTADIRGTVEKIRSQRAYSI
|.| ..|.||| |||... ..|..|..|.... . . ..|.|||||||.||||||..|||....||. .. || .|...|.||. ..
vkhyhytgwpdhgvPeesdsilellravkknknkses...........skpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgmv
QMPDQYVFCHLALI
|. .||.|.. ||.
qteeqylflyrall
|
0038934 |
(Phosphotyrosine protein) phosphatases II |
698-758 |
7.5e-07 |
24.5 |
In-house |
87-135 (194) |
alignment |
Range on Protein: 698-758
Range on HMM: 87-135/194.0
WPDYGVPSSAMAMLNFLQKVREKQAQLVqglgdtwaghprGPPIVVHCSAGIGRTGTFITL
.||.|.. | .|.||. | |. .. | ..||| ||.|||||..
fpddgtvPsleillrfldlvdeflnedp............ggvvaVHCkaGlgRtGtlvaa
|
subfamily_PTPDC1_pd |
Subfamily PTPDC1 |
738-798 |
2.9e-06 |
21.9 |
In-house |
115-169 (182) |
alignment |
Range on Protein: 738-798
Range on HMM: 115-169/182.0
GpPIVVHCSAGIGRTGTFITLDICISRleDVgTADirGTVEKIRSQRAYSIQMPDQYVFCH
| . ||| || |||| |. . .. .. ||. .....||.|. ||| .| ...
g.kvavhChaGlGrtGvliacylvyak..rl.tae..kaiklvrskrpksiqtreqvelvk
|
subfamily_CG42327_pd |
Subfamily CG42327 |
739-805 |
8.5e-17 |
55.8 |
In-house |
248-315 (319) |
alignment |
Range on Protein: 739-805
Range on HMM: 248-315/319.0
PPIVVHCSAGIGRTGTFITLDICISRLEDV-GTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEYA
|.||||| |.||||. |. || | .||. . || .| .| .|| ... .|| | . | |||
GPlvvhcsdGvGrtGlviasdiairsleeskrsvdiPqlvssvrrdrasavltkeqyefiykvlseya
|
subfamily_Cele-PTP-9_pd |
Subfamily Cele-PTP-9 |
740-811 |
8e-07 |
23.4 |
In-house |
150-227 (255) |
alignment |
Range on Protein: 740-811
Range on HMM: 150-227/255.0
PIVVHCSAGIGRTGTFITLDICIS----RLEDVGTA--DIRGTVEKIRSQRAYSIQMPDQYVFCHLALIEYAYSRGML
..|||||.||||. .|. .. |. |. | . .|..||.|. .|. | | |. | .... . .| |
svvvhCstGiGrsaafvlaelvyqkmirsldttetveldylslleelrskrkraihtPlqlafsilmvldlvfpkgel
|
subfamily_Sponge-PTP-7_pd |
Subfamily Sponge-PTP-7 |
741-803 |
1.3e-10 |
35.5 |
In-house |
1-63 (69) |
alignment |
Range on Protein: 741-803
Range on HMM: 1-63/69.0
IVVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIE
.|||||.| |||||||.. . ..|. || | .| | . .|.| | ||.|
mvvhcssgtgrtgtfiaimvemarikseklvdifnnvqymrkcrpmmvmneieyifihdalve
|
subfamily_Sponge-PTP7_pd |
Subfamily Sponge-PTP7 |
742-803 |
3.8e-10 |
34.0 |
In-house |
1-62 (69) |
alignment |
Range on Protein: 742-803
Range on HMM: 1-62/69.0
VVHCSAGIGRTGTFITLDICISRLEDVGTADIRGTVEKIRSQRAYSIQMPDQYVFCHLALIE
|||||.| |||||||.. . ..|. || |. .| | . ..|.| | ||.|
vvhcssGtGrtGtfiaimvemarikseklvdifnnvqymrkcrpmmvmneneymfihdalve
|