Synonym: CG11344, CG31795, CG4355, Dmel\CG31795, R-PTPX/1A2, anon-WO0153538.69, ia2, Dmel_CG31795, IA-2
Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
---|---|---|---|---|---|---|---|---|---|
0039614 | (Phosphotyrosine protein) phosphatases II | 929-1222 | 5e-78 | 257.8 | In-house | 3-289 (297) | alignment | ||
Range on Protein: 929-1222
Range on HMM: 3-289/297.0
WSEEPALTNMDISTGHMVLSYMEDHLRNKGRLQREWEALCRYEAEpsaREAASQPQCAGLNRPGAPLPYDHSRVVLNHLANA-EGLDYVNASTITDHDPR
. ....|....|..... | .. ... .|..|..|.| |... . .. | |. .|| ||||||||.|... . ...||.||| .. .| .
plrdallesipiplsvldlllllekansktllllefeellslkpd...ysiallpenkdknrykdilpydhsrvklkpedgvdldsdYinAsyvdgydll
APAYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCRLQENGEvACARYWPEEGAeVYHIYEVHLVSEHIwCDDYLVRSFYLKNlrTSETRTVTQFHFLSWP
....|.|||||.|...||.|.|||| ||| |..| |.| ||.|||||| .|. . |.|.... .|.| || . ..| ..|.||||.|....||
trkfIatqgPlpetvedFwrmvweqgvtvivmLtklvelgr.kcaqywpeegg.tygdftvtllkveh.ldgytvrtlevtn..ngesrtvthfqytgwp
HMGVPAQAKALLDFRRKVNKSYRGR-RSCPIVVHGSAGAGRTGVYILLDLVLERMNKGaREIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAEEV
..||| .. ||.| ..|.. .. ...|..|| ||| ||||..|...|.||...|. ...|. ....|| || |.| | .|..|. .|..| .
dhgvppslellleflelvrealaelpkggpvlVHCsaGvgRtGtfiaaylmleqleke.ggvdvleavkelreqRpgavqtpsqyrflydallell
|
|||||||||
subfamily_PTPRN_pd | Subfamily PTPRN | 930-1227 | 2.2e-169 | 556.7 | In-house | 1-297 (297) | alignment | ||
Range on Protein: 930-1227
Range on HMM: 1-297/297.0
SEEPALTNMDISTGHMVLSYMEDHLRNKGRLQREWEALCRYEAEPSAREAASQPQCAGLNRPGAPLPYDHSRVVLNHLANAEGLDYVNASTITDHDPRAP
||||...|.||||||.||||.||||.|| ||..||||||.||||||..|.|...... || | |||||||| |.. |.|| ||.|||.|.|||||||
seepvvsnldistGhvvlsyledhlknkdrlekewealcayeaepstkevakaeknvkknrskavlpydhsrvklkeeasaeksdyinasaildhdprap
AYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCRLQENGEVACARYWPEEGAEVYHIYEVHLVSEHIWCDDYLVRSFYLKNLRTSETRTVTQFHFLSWPHM
||.|.||||.||.|.||||.||||.||||.|.||.|.| .|.||||.||.||||||||||||||||||||||||||||||.||||||||||||||||..
ayiatqgplastvadfwqmvweqGvvvivnltrleeegvkqckrywpdeGsevyhiyevhlvsehiwcddylvrsfylknlqtsetrtvtqfhflswpee
GVPAQAKALLDFRRKVNKSYRGrRSCPIVVHGSAGAGRTGVYILLDLVLERMNKGAREIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAEEVHAILK
||||.||.||.||||||||||| ||||||||.|.||||||||||.||||.|..||..|||||||||||||||.|.|.|..||||.|.||||||.||||
gvPasaksllefrrkvnksyrG.rscpivvhcsdGaGrtGvyilidlvlnrllkGvkeidiaatlehlrdqrpglvktkdqfefaltavaeevnailk
|
|||||||||
0050432 | (Phosphotyrosine protein) phosphatases II | 934-1226 | 2.3e-82 | 272.1 | In-house | 19-303 (308) | alignment | ||
Range on Protein: 934-1226
Range on HMM: 19-303/308.0
ALTNMDISTGHMVLSYMEDhLRNKGRLQREWEALCRYEAePSAREAASQPQCAGLNRPGAPLPYDHSRVVLnhlanAEGLDYVNASTITDHD-PRAPAYV
|... . . .| ..|. . ..|.|..|.|.|... . ...|..|. .|| ||||||||.| || ||.||| .. .. . ...
ilvsslklsvldllkllek.aldlglleeefeellsvkp.lleysvallpenkdkNrykdilpydhsRVkl.....degsdYInAsyvdgyssklprkfI
AAQGPLPSTLAHFWQMIWEQGAVVIVALCRLQENGEVACARYWPEE---GAEVYHIYEVHLVSEHIwCDDYLVRSFYLKNLRTSETRTVTQFHFLSWPHM
|.|||||.|...||.|.|||. ||| |..|.||| . ||.|||.| | ..|. . |.|.||.. .||| || ..|.||...|.||||.||...||..
atqgPlpntvedFwrmvweqnvrvIvmLtklvengrekcaqYwplelgggsleygkftvtllseev.lddytvrtleltnlgdgesrtvthfhytnWpdh
GVPAQAKALLDFRRKVNKSYrgrRSCPIVVHGSAGAGRTGVYILLDLVLERMNKGaREIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAEEVHAIL
||| ....|||| ..|.||. ...||||| ||| ||||..|.|||.||...|. ...|. .. .|| ||.|.| | .|..|. .|..| .. .|
gvPpspeilldflelvrksl...pggpivVHCsaGvGRtGtfialdllleqleke.ggvdvfeavkklReqRpgmvqtpeqylflyralleylklkl
|
|||||||||
0051299 | (Phosphotyrosine protein) phosphatases II | 937-1220 | 1.1e-81 | 269.8 | In-house | 2-284 (288) | alignment | ||
Range on Protein: 937-1220
Range on HMM: 2-284/288.0
NMDISTGHMVLSYMEDHLRNKGRLQREWEALCRYEAEpSAREAASQPQCAGLNRPGAPLPYDHSRVVLNHLANAEGLDYVNASTItDHDPRAPAYVAAQG
...||. ... ... ..... .|..|.|.|... . . ||. |. || ||||||||.|..| . || ||.||| | | .. ...|.||
dteisveellklvlkllangltglleefeellsllpd.ltlsaallpenleknRysdilpydhsRVkLsvldgvegsdYinAsyi.dgynlkrkfIatqg
PLPSTLAHFWQMIWEQGAVVIVALCRLQENGEVACARYWPEEGAEVYHIYEVHLVSEHIwCDDYLVRSFYLKNL----RTSETRTVTQFHFLSWPHMGVP
|||.|...||.|.|||. ||| |..|.|.| . ||.|||..| ..|. . |.|.||.. .||| || ....|| ..|.||||.||...||..|||
PlpntvedFWrmvweqnvrvIvmltklvelgrekcaqYwplggsltygditvtllseev.lddytvrtlevtnldlldgdgesrtvthfhytnwpdhgvp
AQAKALLDFRRKVNKSYRgRRSCPIVVHGSAGAGRTGVYILLDLVLERMNKGaREIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAE
...|||| |.|.|... ...|.||| ||| ||||..|.|||.||...|. ...|. ....|| || |.| | .|..|| .|..|
dspellldflrlvrkala.sgggpvvVHCsaGvgRtgtfialdllleqleke.ggvdvleavkrlreqRpgmvqtpeqyrfvyealle
|
|||||||||
0045450 | (Phosphotyrosine protein) phosphatases II | 938-1220 | 4.2e-74 | 245.3 | In-house | 7-302 (307) | alignment | ||
Range on Protein: 938-1220
Range on HMM: 7-302/307.0
MDISTGHMVLSYMEDHLRNKGRLQREWEALCRYEAE-PSAREAASQPQCAGLNRPGAPLPYDHSRVVLNHLANA-EGLDYVNASTITDHDP-------RA
. |.. ...| .....| .. .|..|.| |.... . . ...|. |. .|| |||||.||.|..| . |. ||.||| ...... .
lfidalkllllvllllldfltgllkefekllsvtvfllgeysiallpenkdknrykdilpydhtRVklssldgsledsdYiNAsyvrvpllllldgydlk
PAYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCRLQENGEVACARYWPEEGAE-VYHIYEVHLVSEHIwCDDYLVRSFYLKNL-RTSETRTVTQFHFLSW
...|.|||||.|...||.|.|||| ||| |..| |.| . ||.|||.|| | .|. . |.|.||.. .|.| || . ...| |.|.||||.||...|
rkfIatqgPlpetvedFwrmlweqgvtvivmltelvelgrekcaqywPdegeeltygnftvtllseeh.ldgytvrtlevtdldgtgesrtvthfhytgw
PHMGVPAQAKALLDFRRKVNKSYRGR-RSCPIVVHGSAGAGRTGVYILLDLVLERMNKGARE--IDIAATLEHLRDQRAGVVATRQQFEFVLMAVAE
|..||| . |||| ..|.| .. ...|..|| ||| ||||..|...|.|....|. .|. ....||.|| |.| . .|..|. .|..|
pdhgvppsfeelldfieevrkaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrflyealle
|
|||||||||
0043336 | (Phosphotyrosine protein) phosphatases II | 940-1220 | 9.2e-76 | 250.2 | In-house | 2-275 (278) | alignment | ||
Range on Protein: 940-1220
Range on HMM: 2-275/278.0
ISTGHMVLSYMEDHLRNKGRLQREWEALCRYEAepSAREAASQPQCAGLNRPGAPLPYDHSRVVLNHLANAEGLDYVNASTItDHDPRAPAYVAAQGPLP
||. ... ..| .| .| .|..|.| |... .. | |. .|| ||||||||.|..| . ...||.|||.. | .. ....|.|||||
isvkdllkallelllnlktllllefeellsfkl..dtysiallpenkdknrykdilpydhsrvklsllggdldsdYinAsyv.dgynvprkfiatqgPlp
STLAHFWQMIWEQGAVVIVALCRLQENGEVACARYWPeEGAEVYHIYEVHLVSEHIwCDDYLVRSFYLKNLRTSETRTVTQFHFLSWPHMGVPAQAKALL
.|...||.|.||.| .|| |..| |.| | ||.||| .| ..|. . |.|..|. .||| || . ..||...|.||||..|.|.||..||| . . ||
etvedFwrmvwelgvttivmLtelvelgrvkcaqYwp.ggsltygdftvtllkeeh.lddytvrtlevtnlgdgesrtvthyhylgwpdhgvpeslslll
DFRRKVNKSYRgRRSCPIVVHGSAGAGRTGVYILLDLVLERMNKGArEIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAE
|| ..|.. .. .. |..|| ||| ||||..|.|.|.||...|. ..|. ....|| ||.| | | .|..|. .|..|
dflkavreale.dsngpvlVHCsaGvgRTGtfialyllleqlekeg.gvdleeavkelreqRpgavqtpsqyrflyealle
|
|||||||||
subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 940-1221 | 3.1e-60 | 199.2 | In-house | 16-290 (319) | alignment | ||
Range on Protein: 940-1221
Range on HMM: 16-290/319.0
ISTGHMVLSYMEDHLRNKGRLQREWEALCRYEAEPSAREAASQPQCAGLNRPGAPLPYDHSRVVLNHLANAEGLDYVNASTITDHDpRAPAYVAAQGPLP
. . .. || .| .. .|. |. ..|. .. . .. | .| || . |..|...| |..| |. ||.||| .| . | |.||||||.
fpayyqqlsnksdfdddltklevefrracklgvnladqtfanldqnkdknriinilafdknvvklerliGeefsdyinasfvtGyq.rkdkyiaaqGPld
STLAHFWQMIWEQGAVVIVALCrlqengEVACARYWPEEGAEVYHIYEVHLVSEHiWCDDYLVRSFYLKN-LRTSETRTVTQFHFLSWPHMGVPAQAKAL
||| ||.||||. . || | . |..||| .. . . ..|.. | . ...| ||.. | . . . | .|||||| ||..||| .. |
ntladfWrmiweyncstivllt......kdkcsqywplkivikeerfkvkvdsve.etaeyvvrdielsedgkekdirkitqfhflGwpdvGvpdypsdl
LDFRRKVNK-SYRGRRSCPIVVHGSAGAGRTGVYILLDLVLERMNKgAREIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAEE
. . .||.. . . .|||| |||.||||||| || .|.||.. . .|. ... ||.|| .| |. |. .|. ||
mrlvkkvrhltskenhranivvhcsaGvGrtGvyivldvlldrmke.ekqvdvynfvrdlrqqrntlvqdlvqykfiysallee
|
|||||||||
0040438 | (Phosphotyrosine protein) phosphatases II | 944-1227 | 4.6e-78 | 258.0 | In-house | 4-281 (317) | alignment | ||
Range on Protein: 944-1227
Range on HMM: 4-281/317.0
HMVLSYMEDHLRNKGRLQREWEALCRYEAEpsAREAASQPQCAGLNRPGAPLPYDHSRVVLNHLANAEGLDYVNASTItDHDPRAPAYVAAQGPLPSTLA
...| .. .......|..|.| |... . .. |. |. ..|| ||||||||.|..| . ...||.||| . | . ....|.|||||.|..
dlllalldllksdftalleefedllslkld..tysvaelpenkdknrypdilpydhsRVkLsplggdldsdYInAsyv.dgpnlkrkfIatqgPlpntve
HFWQMIWEQGAVVIVALCRLQENGEVACARYWPEEGAEVYHIYEVHLVSEHIwCDDYLVRSFYLKNLRTSETRTVTQFHFLSWPHMGVPAQAKALLDFRR
.||.|.|||| ||| |..| |.| . ||.|||... .|. . |.|.||. .... .| . ...|..||.||||.||...||..||| . |||| .
dFwrmvweqgvtvivmLteleelgrekcaqYwplgetltygdftvtllseee.lagitlrtlevedlgdsesrtvthfhytgWpdhgvppspdllldfle
KVNKSYRgRRSCPIVVHGSAGAGRTGVYILLDLVLERMNKGArEIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAEEVHAILK
.|..... ....|..|| ||| ||||..|...|.||...|. ..|. ....|| ||.|.| | .|..|. .|..| . |.
avreale.dpggpvlVHCsaGvgRtGtfiaaylmleqlekeg.gvdveeavkelreqRpgavqtpeqyrflydalleylkrklt
|
|||||||||
subfamily_Ptp69D_pd | Subfamily Ptp69D | 947-1221 | 5.8e-56 | 184.9 | In-house | 11-285 (307) | alignment | ||
Range on Protein: 947-1221
Range on HMM: 11-285/307.0
LSYMEDHLRNKGRLQREWEALCRYEAEPSAReAASQPQCAGLNRPGAPLPYDHSRVVLNHLANAEGLDYVNASTITDHDPRApAYVAAQGPLPSTLAHFW
.. . . |..|.| | . | . |.. .. . | || . ..|. ||.|... | ||.||| | .. . ..|||.|. .|. ||
ealksrkrdtdfglakeyekLeareidkstk.vsekkenalknRyedikafDktRvkLkkingkedsdYinasfikgykekk.kfiaaqdPveatigDfW
QMIWEQGAVVIVALCRLQENGEVACARYWPEEGAEVYHIYEVHLVSEHIwCDDYLVRSFYLKNLR-----TSETRTVTQFHFLSWPHMGVPAQAKALLDF
.||.|| .|| | |.| . ||.|||.| | |.||||. ..|| |.... . ..| |.|.|...|. . || .|..||..
RmiaeqevtlivmlsnlteknrkkcakYWpiedevqygdilvklvseek.hsdyiiReldvskkkeesgevedsrkvvqyhytgWkDskvPevargllkl
RRKVNKSYRGRRScPIVVHGSAGAGRTGVYILLDLVLERMNKgAREIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAEE
..|.. |. || ||||| |||.||.|... ||..|..... ..|| .| .|| || .| .|..|. |...
ieqvrelyklnrs.PivvhCsaGvgrsgifvaldsllqqlka.edkvdifetvkdLrsqRnllvqsleqYvflyralldy
|
|||||||||
0047943 | (Phosphotyrosine protein) phosphatases II | 949-1220 | 1.5e-76 | 252.7 | In-house | 3-270 (273) | alignment | ||
Range on Protein: 949-1220
Range on HMM: 3-270/273.0
YMEDHLRNKGRLQREWEALCRYEAePSAREAASQPQCAGLNRPGAPLPYDHSRVVLnhlaNAEGLDYVNASTItDHDPRAPAYVAAQGPLPSTLAHFWQM
.. ..| ....|..|.|.|... . ...|. |. .|| ||||||||.| . .| ||.||| . | .. ....|.|||||.|...||.|
lllekllgltllleefelllslkp.lltysvallpenkdknrykdilpydhsrvkl....gdggsdyinAsyv.dgynlkrkfiatqgPlpntvedfwrm
IWEQGAVVIVALCRLQENGEVACARYWPEEG---AEVYHIYEVHLVSEHIwCDDYLVRSFYLKNLRTSETRTVTQFHFLSWPHMGVPAQAKALLDFRRKV
.|||.. ||| |..|.|.| . ||.|||.|| ..|. . |.|.||.. .||| || ..|.|| |.|.||||.||...|| .|||.. . ||.| ..|
vweqnvrviVmLtelvelgrekcaqYwpleggelsltygkftvtllseet.kddytvrtleltnlgtgesrtvthfhytgwpdhgvppslesllefielv
NKSYRGR-RSCPIVVHGSAGAGRTGVYILLDLVLERMNKGaREIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAE
.| .. .. |.||| ||| ||||..|.|||.|....|. ...|. .. .||.|| |.| | .|..|. .|..|
rkalealpsngpvvVHCsaGvgRtgtfialdllldqleke.ggvdvleavkllrsqRpgmvqtpeqyrflyealle
|
|||||||||
subfamily_PTPRB_pd | Subfamily PTPRB | 949-1220 | 2.4e-66 | 218.7 | In-house | 16-283 (293) | alignment | ||
Range on Protein: 949-1220
Range on HMM: 16-283/293.0
YMEDHLRNKGRLQREWEALCRYEAEPSaREAASQPQCAGLNRPGAPLPYDHSRVVLNHLANAEGLDYVNASTITDHDPRApAYVAAQGPLPSTLAHFWQM
... . ... |.. |.| | . . . .||.... . || |||||||| |..|.. .| ||.||. | .. . ..|.|||||.|. .||.|
vkkmkadsdlrfseeyeelkavgkdqa.vkaaelavnraknrytnilpydhsrvkLaalkdesgsDYinanyipgynspr.efiatqGPlpetvddfWrm
IWEQGAVVIVALCRLQENGEVACARYWPEE-GAEVYHIYEVHLVSEHIwCDDYLVRSFYLKNlrTSETRTVTQFHFLSWPHMGVPAQAKALLDFRRKVNK
.||. . .|| | .| |.| | | .|||.. . .| .|.||.|. .|. .|.. ... ..|.|.|.|.||.||| ||| ..|.|||| |.|..
vwekkssiivmltqlvekgkvkCeeYWPadeepvlyGdikvtlvaeee.ledwvirelkiek..ekeerkvrqyhftsWpdhgvPektktlldfvrtvre
SY-RGRRSCPIVVHGSAGAGRTGVYILLDLVLERMNKgAREIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAE
. . .. ||||| ||| ||||..| || .|..... .||.... .|| .|. .| | .|. |. .| .
aiektaskrPivvhCsaGvGRtGtfialdrllqaiee.edyvdifgivaelReeRnllvqtekqYifihqcvld
|
|||||||||
subfamily_PTPN6_pd | Subfamily PTPN6 | 949-1222 | 1.3e-64 | 213.2 | In-house | 18-297 (306) | alignment | ||
Range on Protein: 949-1222
Range on HMM: 18-297/306.0
YmEDHLRNKGRLQREWEALCRYEAE-PSAREAASQPQCAGLNRPGAPLPYDHSRVVLNhLANAEGLDYVNASTITD-HDPRAPAYVAAQGPLPSTLAHFW
|.. .| .. |.|.| . ||. |. ...|. . || . ||.||.||.|. . | ||.||. |.. .|.|.|| |..|.. ||
k.eeeslekagfeeefeelqqeeakkllsrkegakpenkeknryknilPfDhtrvilk.epsvpgsdyinanyikkevkgsdksyiatqgclettvsdFW
QMIWEQGAVVIVALCRLQENGEVACARYWPEEGAE-VYHIYEVHLVSEhIWCDDYLVRSFYLK-NLRTSETRTVTQFHFLSWPHMGVPAQAKALLDFRRK
.|.|.. . ||| . . | |. ||||||.| .. | ..|. ||| .|| .|.. .. . . .|.|.| |.|| ||| |||.. .|.||| ..
rmvwqensrvivmttkevErgkekCarYWPdeeekeeyGkisvtnvse.ksladYilRelsvskkkkkkeerevfqyhfksWPdhgvpkdpgavLdfled
VNKSYRGRR---SCPIVVHGSAGAGRTGVYILLDLVLERMNKG--AREIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAEEV
||. .. . . ||||| ||| |||| .|..|..|. ..| .||| . . .|.|| |.| | ||. || .|... .
vnrkqeeleeaeagpivvhCsaGiGRtGtfiviDillkliekkgldadidiqklvksvreqrsglvqteqqykfvykaikkyi
|
|||||||||
subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 949-1224 | 1.6e-59 | 196.5 | In-house | 13-285 (305) | alignment | ||
Range on Protein: 949-1224
Range on HMM: 13-285/305.0
YMEDHLRNKGRLQREWEALCRYeAEPSarEAASQPQCAGLNRPGAPLPYDHSRVVLNHLANAEGLDYVNASTITDHDpRAPAYVAAQGPLPSTLAHFWQM
.|.. .. |. ....|.. |. . .. . . || .. ..|..|. |.. . . ||.||| . .. | .|..|||||..|.| ||..
ikearvysdkgleaqykslyee.eesi..dvgkkeankaknrlkeitlldddriiltekeslddsdyinasyvdgyk.rkkkyivaqgPlkntvadfWrl
IWEQGAVVIVALCRLQENGEVACARYWPEEGAE--VYHIYEVHLVSEHIwCDDYLVRSFYLKN-LRTSETRTVTQFHFLSWPHMGVPAQAKALLDFRRKV
|.| ..|| |..|.|.|. | .||||. .| . ..|.| ||. ||. | . . . .|.|||.|... .|| ||| .| .||.. ..|
iveekvstivmltklveggkdkCrqYWpesktekkefgefsvelksekt.asdyieRklkisiededkesrtvlqyqltdWPdhGvpqfatsllslikrv
NKSYRGRRSCPIVVHGSAGAGRTGVYILLDLVLERMNKGaREIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAEEVHA
.|... . |..|| ||| |||||.| .|. |||..| ..|.. | .|| .| ..| | .|. |. |..|....
qkdqkkdkgvpllVhCsagvgRtGvfiavdialerlkkE.evvdvfevlkqlRskrmkmvqtldqYvflhdaldelitc
|
|||||||||
subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 950-1224 | 1.2e-65 | 216.7 | In-house | 15-285 (319) | alignment | ||
Range on Protein: 950-1224
Range on HMM: 15-285/319.0
MEDHLRNKGRLQREWEALCryEAEPSAREAASQPQCAGLNRPGAPLPYDHSRVVLNHLANAEGLDYVNASTITDHDPRApAYVAAQGPLPSTLAHFWQMI
.. . . |..|.. | ||.. . ||... || |.||..|||| .| . || ||.||| | .. | ...|.|.|| |. ||.|.
kalastgetllekefkllk..eavndtfdsaskeenkkknryqnilaydrtrvvlseldgvegsdyinasfidgyqere.kfiatqaPlentiedfWrmv
WEQGAVVIVALCRLQENGEVACARYWPEEGAEVYHIYEVHLVSEHiWCDDYLVRSFYLkNLRTSE--TRTVTQFHFLSWPHMGVPAQAKALLDFRRKVNK
||... ..| |..|.|...| . .||||| |.| . | | .|. .|| .| . | | ..|| ||.|..|....|| .|| .|..|||. ....|
WeeessivvmltklveklkvklkkywpeenfeeyGrlivtleeee.eledyiirklkl.nkkssevetRevkhfqyteWpdhdvPekatslldllkrirk
SYRGRRSCPIVVHGSAGAGRTGVYILLDLVLERMNKGArEIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAEEVHA
| .. | ||||| |||.|||| .| || .|||... . .|. | .|| || .| . .|..|. |. | |.|
srektqsgPivvhCsaGvGRtGtfivldamlervkeeg.vlDvfstvsrlRtqRnimvqrpeqYkfiyealleavea
|
|||||||||
subfamily_PTPN23_pd | Subfamily PTPN23 | 950-1226 | 1.2e-55 | 183.3 | In-house | 7-284 (288) | alignment | ||
Range on Protein: 950-1226
Range on HMM: 7-284/288.0
MEDHLRNKGRLQREWEALCRYEAEPSAREA-ASQPQCAGLNRPGAPLPYDHSRVVLNhlanAEGLDYVNASTITDHDPRAPAYVAAQGPLPSTLAHFWQM
. | .|. |..... | ..... . . | . || |||||.||.|. . ||.||| . | | .| ..|.|.||.|||. ||.|
qrkmldgktaldkkfkeleqkqdkearkrsiaiaklyseknrsrdilPyDhnRvklr....gskDDYinAsfvkdlspgcPdfiatqaPlqstlnDFWlm
IWEQGAVVIVALCRLQENGEVACARYWPEEGA--EVYHIYEVHLVSEHiWCDDYLVRSFYLKNLRTSETRTVTQFHFLSWPHMGVPAQAKALLDFRRKVN
..|| . ||| | .| |. ..|||||. ... ..| | |.. . . | . |. |.......|. .. |||..|||| . ||.| .|.
vyeqkssviVmllskeelgkpkvdrYwPedkgetvkfgdlsvtlksvr.etethvervlkletldadavksvshlqltsWpelGvPasPetllqfldeve
K---SYRGRRSCPIVVHGSAGAGRTGVYILLDLVLERMNKGAREIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAEEVHAIL
. . . . |.||| ||| |||||. |. ... ..|| .|| ...|| || .| ...|..|.. || |... .|
sayeavqrksktPlvvhCsaGvgRtgvfalvyaavrelekgnglldiiqvvsrlreqRrfmvqekeqlkfsyeavleaarrvl
|
|||||||||
0036941 | (Phosphotyrosine protein) phosphatases II | 951-1221 | 8.5e-74 | 243.8 | In-house | 6-276 (297) | alignment | ||
Range on Protein: 951-1221
Range on HMM: 6-276/297.0
EDHLRNKGRLQREWEALCRYEAEPSaREAASQPQCAGLNRPGAPLPYDHSRVVLnhlaNAEGLDYVNASTItDHDPRAPAYVAAQGPLPSTLAHFWQMIW
..| .. .|..|.| |... . .| ...|. |. .|| |||||.||.| . || ||.||| . | . ...|.|||||.|...||.|.|
lekllflalllkefeellpllllgs.lsvallpenleknRykdilpydhtRVkl....ddegsdYinAsyv.dgydlkrkfIatqgPlpntvedFWrmvw
EQGAVVIVALCRLQENGEVACARYWPEE--GAEVYHIYEVHLVSEHIW-CDDYLVRSFYLKNLRTSETRTVTQFHFLSWPHMGVPAQAKALLDFRRKVNK
||. ||| |..| |.| . ||.|||.| . .|. . |.|.|.... .||| .| . .......|.||||.||...||..||| .. |||| ..|.|
eqnvtvIvmltelvelgrekcaqywpleegesltygdftvtllsvevvllddytlrtlevtdtgngesrtvthfhytgwpdhgvpespaslldfielvrk
SYRGR-RSCPIVVHGSAGAGRTGVYILLDLVLERMNK--GAREIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAEE
.. .. |..|| ||| ||.|..|..||.|..... ...|| .. .||.||.|.| | .|..|. .|..|
vlkllpsggpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyeallel
|
|||||||||
subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 951-1224 | 3.3e-52 | 172.2 | In-house | 13-285 (290) | alignment | ||
Range on Protein: 951-1224
Range on HMM: 13-285/290.0
EDHLRNKGRLQREWEALCRYEAEPSAReAASQPQCAGLNRPGAPLPYDHSRVVLNHLANAEG--LDYVNASTITDHDPrAPAYVAAQGPLPSTLAHFWQM
..| ... . . ....| | | .. . .. ||| ..|| |..|..... . .|.||. | .. . .|.|.|||...||..||..
nghakgnegfrnqfkmldsgesehtvt.vgltssnkllnRfanivvyddnritLrpisghkDCtneyinAcyikgyke.kkqyiatqgpvsntlvdFWkl
IWEQGAVVIVALCRLQENGEVACARYWPEEGAEVYHIYEVHLVSEHIWCdDYLVRSFYLKNLRT-SETRTVTQFHFLSWPHMG-VPAQAKALLDFRRkVN
||.. .|| |. .|.|.| | |||..... | ....|..|.. .| | . .|| .. ....|||... .|.. | |.... || ... ..
iwqekvtiivmltniieegkvkCqqYWpdsdtkaygefsikllneetln.eyierklevknknsagakqsvtqyqitnwdstgkvtnpqtillviee.my
KSYRGRRSCPIVVHGSAGAGRTGVYILLDLVLERMNKgAREIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAEEVHA
| | | .|||| |.. ||..|.. .. ...... ||. . |...| |. | | | ||.... | . ..
ktqrkrgntsivvHCSdtvgrsavfcaaattinkckt.egvidvfqvlksqRiqkpgsvqtvqqyqgifqivltylds
|
|||||||||
subfamily_PTPN14_pd | Subfamily PTPN14 | 951-1218 | 1.6e-51 | 170.1 | In-house | 17-292 (300) | alignment | ||
Range on Protein: 951-1218
Range on HMM: 17-292/300.0
EDHLRnKGRLQREWEALCRYEAePSAREAASQPQCAGLNRPGAPLPYDHSRVVLNHLANAeGLDYVNASTITDH-DPRAPAYVAAQGPLPSTLAHFWQMI
| .|. .|.. |.| . . .. . ..|. |. | || |||...|| |. .. .|.|||.| . |..|||||. |. ||||.
ekkle.egkvfteyeripkkre.dallstaklpenaeknrfkdvlPyednrvelsptken.stgyinassikvsvggkersyivaqgPleltvqdfWqmv
WEQGAVVIVALCRLQENGEVACARYWPEEGAEVYHI-YEVHLVSEHIW--CDDYLVRSFYLKNLRTSETRTVTQFHFLSWPHMGVPAQAKALLDFRRKVN
|||| .|| | . .|.| . .|.|... . .. .. . |... | . ... || | ..| ||| . . || ||| | |.. ..|.
WeqgvqlivmlteeeedgkeksfkyfPkleskkktvefgkfkvttkfsedsdsvittglklkhlpskeertvwhlqytDWpdhgvPeDvkgflsyLeevq
-------KSYR-GRRSCPIVVHGSAGAGRTGVYILLDLVLERMNKGaREIDIAATLEHLRDQRAGVVATRQQFEFVLMAV
.. .. |..|| |||.||||| || ||... .... .|||| .|..|| || .|.| |..|| ..
svrrktnseveskeskPPvlvhCsaGvGrtGvlilsdlliatlehn.eeidikkvlarLreqrmllvqtlaqYkfvYkvl
|
|||||||||
subfamily_PTPN3_pd | Subfamily PTPN3 | 952-1220 | 4.6e-59 | 194.6 | In-house | 10-273 (280) | alignment | ||
Range on Protein: 952-1220
Range on HMM: 10-273/280.0
DHLrNKGRLQREWEALCRYEAEPsAREAASQPQCAGLNRPGAPLPYDHSRVVLNhlaNAEGlDYVNASTITDHDPR---APAYVAAQGPLPSTLAHFWQM
. | ..|.. ..| | | . . | .|| .|. . || ||||. || |. ..| ||.||... | |.|.||||..| ..||||
egl.esGavlaqfeqlyrkkpgl.aisaarkpenlsknryrdilpydatrvklk...eset.dyinanyvnmeipstglvnryiatqGPlaktatdfWqm
IWEQGAVVIVALCRLQENGEVACARYWPEEGAEV-YHIYEVHLVSEhIWCDDYLVRSFYLKNLRTSETRTVTQFHFLSWPHMGVPAQAKALLDFRRKVNK
.||| . .|| | | |.| | | .||||.. |. | ..|.. .| |..| ..||. .|.| |...|. .|.|| ||| ... .|.| ..|.|
vweqksslivmlttlverGrvkChqyWPetedeleygefsvkceke.detksyvlrelvlkdketkeerkilqlqylaWpdhgvPddsadflefvervrk
sYRGRRSCPIVVHGSAGAGRTGVYILLDLVLERMNkGAREIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAE
.| .. |.||| ||| |||||.|||.. | .. |... . . . ..||||| .| | .|..|| |. .
.lrsgkeePvvvhCsaGigrtGvlilletalalie.aaepvypldivrtmrdqramlvqtasqykfvCeailk
|
|||||||||
subfamily_PTPRG_pd | Subfamily PTPRG | 953-1224 | 3.6e-59 | 195.4 | In-house | 14-289 (563) | alignment | ||
Range on Protein: 953-1224
Range on HMM: 14-289/563.0
HLRNKGRLQREWEALCRYEAEP-SAREAASQPQCAGLNRPGAPLPYDHSRVVLNHLANAEG-LDYVNASTITDHDpRAPAYVAAQGPLPSTLAHFWQMIW
| .. ....|.||| . .. |....|. || ..||.||| |. |.. .. |||.||. | . .. |..|.||||..|. ||.|||
hadgdigfseefealqsetiskdldaehsqkpenkrKnRylnivaydrsRvklsplpgkkkklDYinAnyidGyq.kskafiatqgplkdtfddFWrmiW
EQGAVVIVALCRLQENGEVACARYWPEEGAEVYHIYEVHLVSEHIWCDdYLVRSFYLKNLRTSE------TRTVTQFHFLSWPHMGVPAQAKALLDFRRK
|| . .|| . |.|.| | .|||....| | .| |..|.. . | ||.. .|||. . ..|.|.|. .|| .||| .. | | .|
eqnvaiivmitnlvergrrkcdvYWPkdesetygalqvtlieeevlal.ytvrtlviknlklkkkkqcdteklvrqyhytkWPdhgvPehslpvLifvkk
VNKSYRgRRSCPIVVHGSAGAGRTGVYILLDLVLERMNKgAREIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAEEVHA
... . . ||||| |||.||||.|| || .|..... ... .| |.| || .|.|. |. |. |. | . .
ssaank.aeaGPivvHcsaGvgrtGtyivldtllkqiqq.enavnvfgflkhiraqRnflvqteEqYiflhdalleaias
|
|||||||||
subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 954-1219 | 2.1e-63 | 209.1 | In-house | 17-276 (288) | alignment | ||
Range on Protein: 954-1219
Range on HMM: 17-276/288.0
LRNKGRLQREWEALCRYEAEPsAREAASQPQCAGLNRPGAPLPYDHSRVVLNHLANAEGLDYVNASTITDHDpRAPAYVAAQGPLPSTLAHFWQMIWEQG
||. ...|...| | . . .|..... | || ||||. || |..| . .| ||.||| | ... . .|.|.||||..|. .||....|.
arnrtgfseeynsLaalektk.svtagrlavnakknRyrnilpyDekrvklkkleeeagaDYinasyidgek.kkkkyiatqgPladtvndfWelvyenk
AVVIVALCRLQENGEVACARYWPEEGA-EVYHIYEVHLVSEHiWCDDYLVRSFYLKnlRTSETRTVTQFHFLSWPHMGVPAQAKALLDFRRKVNKSYRGR
. || | | |.|. | .|||... . | .| ||... .|...|.. |. .. . ...||...|.|| .|||.... ||...|.|. .
tstivmltelveggktkCeeYWPdadkpknyGsvtvtlvesk.eledfvlrkllle..kkkteleitqyqylaWpdhgvPeskapllellrqvkvanqad
rSCPIVVHGSAGAGRTGVYILLDLVLERMNKgAREIDIAATLEHLRDQRAGVVATRQQFEFVLMAVA
. ||.|| ||| ||||..| || ....... ||.|.|...|| ||| .| | .|.||. ...
.tgpiivhCsaGvGrtgtFialdalidavee.edyiDvagtvaklRkqRallvqtlkqYefiyevll
|
|||||||||
subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 954-1219 | 5.2e-50 | 164.9 | In-house | 6-274 (287) | alignment | ||
Range on Protein: 954-1219
Range on HMM: 6-274/287.0
LRNKGRLQREWEALCRY-EAEPSAREAASQPQCAGLNRPGAPLPYDHSRVVLNHLANaEGLDYVNASTITDHDpRAPAYVAAQGPLPSTLAHFWQMIWEQ
.| | ...| .||.. |. . || . . || . ||.|..||.| . .. | ||.|| .. . . |..|||||...|. ||....|.
rrvkddvdkevdalkedsesstatfkaaeelaavkknryadvlPiddtrvllsaege.lGsdyinanyvasyt.ddeafiaaqgPiaatvrdfwravlet
GAVVIVALCRLQENGEVACARYWPEEGAEV-YHIYEVHLVSEHIWCDDYLVRSFYLKNLRTSETRTVTQFHFLSWPHMGVPAQA----KALLDFRRKVNK
. ... . | |.. | .|||| . | | |.. | .| ||.. | .| | |.| | |...|||| ... | . || .....
rsasvitmtreveearlkcykywPerevPmrvGGysvvlldydikePeygvralrlidletrearvvkqldllswPdkvlaPtavglirfvldvkqhiel
SYRGRRSCPIVVHGSAGAGRTGVYILlDLVLERMNKGAREIDIAATLEHLRDQRAGVVATRQQFEFVLMAVA
. . |.||| ..|.||.|... ||| .. . ..|.||.. .|| .||..| . |. .. |..
ardasevGPlvvhddvGiGrsGilla.tlvlvsrledlGrvdvaavvirlreyraalvqavvqlrllyealv
|
|||||||||
subfamily_PTPRD_pd | Subfamily PTPRD | 955-1257 | 5.9e-83 | 274.4 | In-house | 20-314 (564) | alignment | ||
Range on Protein: 955-1257
Range on HMM: 20-314/564.0
RNKGRLQREWEALCRYeaEPSAREAASQPQCAGLNRPGAPLPYDHSRVVLNHLANAEGLDYVNASTITDHDpRAPAYVAAQGPLPSTLAHFWQMIWEQGA
.. ....|.. . . . . |||..|. || ..||||||||... . || ||.||| | .. . ||.|.||||..|.. ||.|.|||
nsdlkfeeeykkieeg..qqftweaankpaNkaKNRyanivaYdhsRVvLskvegdegsDYINAsfidgyr.krkayIAtqgPlaetiedFWRmvweqns
VVIVALCRLQENGEVACARYWPEEGAEVYHIYEVHLVSEHIwCDDYLVRSFYLKNLRTSETRTVTQFHFLSWPHMGVPAQAKALLDFRRKVNKSYrGRRS
.|| | .|.|.|.| |..||||.| | | ..| |..|. || .|.| ||. ..||.|.|.|||| |||. ||| .|..|||..|||... . .
stiVmltkleEkgkvkchkYWPekgtetygeltVtleeeee.ladyeirtfklkkkkssesreVrqFhFtsWPdhgvpesatslLdlirkvraln.epda
CPIVVHGSAGAGRTGVYILLDLVLERMNKgAREIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAEEVHAILKALPANTSgeKRELDKDPVVGGGSSSTT
||||| ||| ||||..| .| .|||... . .|| ....|| || .| |..|. |. |..| ... . ..... |..|.| | ....|.
gPivVhCSaGVGRTGtfividamlerike.ektvDiyqyvkalrkqRnamVqteeQYiFiheailealacgntevesenl..kqhlqkLaeveedtemtg
TKE
.
lel
|
|||||||||
subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 955-1225 | 2.5e-65 | 215.4 | In-house | 11-279 (281) | alignment | ||
Range on Protein: 955-1225
Range on HMM: 11-279/281.0
RNK-GRLQREWEALCRYEAEPSArEAASQPQCAGLNRPGAPLPYDHSRVVLNHLANAEGLDYVNASTITDHDPRApAYVAAQGPLPSTLAHFWQMIWEQG
.|. ...|.|.| . . .| .|. ... || ||..||.... ... ||.||. . . . .|.|.|||.|..|..||||.|||
qndnaGfieeyeklaaigvdnta.taskadenvlknrYsnivaYDatrvkvtpneenkntDYinanfvpgykgek.eyiatqgPvPaslvafWqmvweqk
AVVIVALCRLQENGEVACARYWPEEGAEV-YHIYEVHLVSEHiWCDDYLVRSFYLkNLRTSETRTVTQFHFLSWPHMGVPAQAKALLDFRRKVNKSYRGR
. .|| . | |.| . | ||||.. .|. | . |. ..|. |. | | | . ...|||.|.|.....|| ||||..|.||.||..|.| . .
vsaivmvtreieagklkChrYWPddnselkygdvtvkstaee.ekatyierkfkl.eresgetreveqlaytaWPdhGvPattkellefrkevlkltekk
RSCPIVVHGSAGAGRTGVYILLDLVLERMNKGAREIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAEEVHAI
. .|.|.| ||| ||||.|| || ....... ..|.|. |....|| .| .| | |.||| || . ..
tkaplvihCsaGvGrtGtyialDrlvkaveaeleeldvkavvaelrkernlmvqtvvqyefvykavldaldke
|
|||||||||
subfamily_PTPN9_pd | Subfamily PTPN9 | 955-1220 | 5.6e-58 | 191.3 | In-house | 11-288 (297) | alignment | ||
Range on Protein: 955-1220
Range on HMM: 11-288/297.0
RNKGR--LQREWEALCRYEAEPSArEAASQPQCAGLNRPGAPLPYDHSRVVLNHLANAEGLDYVNASTItDHDPRAPAYVAAQGPLPSTLAHFWQMIWEQ
..||. |..|.... . ..| . .|. .. || | ||..||||... . | ||.||. . | . |..|.||||. | ||.|.|||
kekgkrGlskeyaeirnepveGtf.lasklranleknrytdvlcydetrvvlakvdedeasdyinanfv.dGykqkkafiatqGplkktvsdfWrmvWeq
GAVVIVALCRLQENGEVACARYWP--EEGAEVYHIYEVHLVSEHIwCDDYLVRSFYLKNLRTSETRTVTQFHFLSWPHMGVPAQAKALLDFRRKVNK---
..||| |. |.| . |..||| || .. . ..|. |. . .|| ||.. .|| .|.|.|.|| | ||||| ||| .|..|||...|| .
evlvivmttrvvergrlkcgqyWpleeessaefgdlsvsnvevee.eedykvrvleiknvkteesrkvthfqflsWPdyGvPssaaslldvlekvrekqa
--------SYRGR-RSCPIVVHGSAGAGRTGVYILLDLVLERMNKGArEIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAE
. .|. . ||||| ||| |||| .| ||. |.|... . .|. |...|| ||| . | .|.|| .|| |
lavkelgdewkghpsgPPivvhcsaGiGrtGtfitldiclsrleevg.tvdvvetvkllrtqrafsiqtpeqyefcylavle
|
|||||||||
subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 957-1231 | 1.8e-71 | 235.8 | In-house | 17-289 (318) | alignment | ||
Range on Protein: 957-1231
Range on HMM: 17-289/318.0
KG--RLQREWEALCRYEAEPSAREAaSQPQCAGLNRPGAPLPYDHSRVVLNHLANAEGLDYVNASTItDHDPRAPAYVAAQGPLPSTLAHFWQMIWEQGA
.| |..|.|.| | |..... .. .| . || |.|||.|| |..|.. || ||.||. | | | ||.|||.||| |. ||.|.|||..
sGelllseeyerlsrseetvtslks.lepvnkaknryanilaydhtrvkLqmlegeegsDyinanyi.dGyrrkkayiaaqaPlpetieDfWrmvWeqns
VVIVALCRLQENGEVACARYWPEEGAEVYHIYEVHLVSeHIWCDDYLVRSFYLKNLRTSETRTVTQFHFLSWPHMGVPAQAKALLDFRRKVNKSYRGRRS
||| | ...|.| . ..||||..|.. | |.| . .. ..||..|.| ... ..|.|.| |.|. ||| |||... |||. |.|.| .
avivmltqeeergkakvhryWPskgsrsygklvvelke.evelsdyvlrefkvtrteeeesrqvrqyhytsWpdegvpesgaslldlvrqvskaqqksga
CPIVVHGSAGAGRTGVYILLDLVLERMNKGArEIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAEEVHAILKALPA
||||| ||| |||||.| .| .|||... | .|. | ..||.|| .| |..|.||. .. | ... . |
gpivvhCsaGvGrtGvfiavdillerikaea.lvDvfqtvkqlreqrnlmvqtedqyefiydvllealasgdtevda
|
|||||||||
subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 958-1223 | 4e-67 | 221.6 | In-house | 27-291 (298) | alignment | ||
Range on Protein: 958-1223
Range on HMM: 27-291/298.0
GRLQREWEALCRYEA--EPSAREAASQPQCAGLNRPGAPLPYDHSRVVLNHLANAEGLDYVNASTITDHDPRApAYVAAQGPLPSTLAHFWQMIWEQGAV
... |.. | . . | |.|..|. || ...|.|||||.. . | ||.||| . .. | |..|.|.||..|.. ||.|..|. .
tgyalefqrlnsvsseieeeekevarkpenkkkNRyadiialdssRvvLekedadeesdYiNAsflhaykgrn.afiatqaPltetvedFWrmvteedig
VIVALCRLQENGEVACARYWPEEGAEVYHIYEVHLVSEHIWCdDYLVRSFYLKNLRTSETRTVTQFHFLSWPHMGVPAQAKALLDFRRKVNKSYRGRRSC
.|| | |.| ... . .|||.||.| | .|.| |.. |. || . ... .....|.| |.|| ||| |||..|...||..|||..| .
tiVmltnleeldktkyhkywPdegketygeitvsllskeefa.dlivrklkvskkkeekerevrqlhftsWpdkgvpenatsvldllrkvrasqqqagnk
PIVVHGSAGAGRTGVYILLDLVLERMNKgAREIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAEEVH
|..|. ||| ||.| .| .| ||||..| . .|. ... || .|.|.| |..|. |. .|| | ..
pvivqCsaGvgRsGtfiaidsvlervkk.eqvvDvfqvvkvlRkkrpgavqteeqYvfiyeavleald
|
|||||||||
subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 959-1227 | 2.3e-25 | 84.1 | In-house | 7-264 (267) | alignment | ||
Range on Protein: 959-1227
Range on HMM: 7-264/267.0
RLQREWEALCRYEAEPSAREAASQPQCAGLNRPGAPLPYDHSRVVLNHLANAegldYVNASTITDHDpRAPAYVAAQGPLPSTLAHFWQMIWEQGAVVIV
...|.| . . . | . . || ||||..||.| . |.||| . . . |... |.|| | ..|...| .|. |||
eiekefelikkisdtsstisqsiaeknqernrlddnlpyddtrvilrtkeee....yinasyvegyk.tknafivtqdplkntitdfltvihdqkvpviv
ALCRLQEnGEVacARYWPEE--GAEVYHIYEVHLVSEHiWCDDYLVRSFYLKnLRTSETRTVTQFHFLSWPHMGV-PAQAKALLDFrrkVNKSYRGRRSC
| . . ... ..|| . |. |. | |. .|| . .. || .. .. || ... | | |. . | .
lltkvft.dni..rlfwPPkmgqakkyqdltvehslek.eendyqiitlelk.fknesahnvtlyyykkwnintnnkpylkplfgi...laknqlengnr
PIVVHGSAGAGRTGVYILLDLVLERMNKgAREIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAEEVHAILK
|.||. |.| ||.| .. .| |||. . || | ..|.|| |.| |.... .. .|| . ||
PlvvacsdGvGrsGtflvidsqlerakt.egvsdifdflrkirsqriglvdtkeryiyihellaeyaegrlk
|
|||||||||
0046845 | (Phosphotyrosine protein) phosphatases II | 960-1225 | 2.6e-77 | 255.3 | In-house | 2-277 (284) | alignment | ||
Range on Protein: 960-1225
Range on HMM: 2-277/284.0
LQREWEALCRYEAEPS-AREAASQPQCAGLNRPGAPLPYDHSRVVLNHLANA-EGLDYVNASTITDHD----PRAPAYVAAQGPLPSTLAHFWQMIWEQG
|..|.|.|... .. ...| |. .|| ||||||||.|..| . |. ||.||| .. .| . ....|.|||||.|...||.|.|||.
leeefeellsltvklllslsvallpenlsknRykdilpydhsRVklksldgdledsdYinAsyvdgydldltyikkkfIatqgPlpntvedFwrmvweqn
AVVIVALCRLQENGEVACARYWPEEG-AEVYHIYEVHLVSEHIwCDDYLVRSFYLKNLR-TSETRTVTQFHFLSWPHMGVPAQAKALLDFRRKVNKSYRG
. ||| |..| ||| . ||.|||.|| .|. . |.|.||.. .||| || ..|.|| |.|.||||.||..|||..|||.... ||.| |.|.....
vrvIVmltelvengrekcaqYwplegevltygdftvtllseev.kddytvrtleltnlgytgesrtvthfhytswpdhgvppspedlleflrlvrellen
-RRSCPIVVHGSAGAGRTGVYILLDLVLERMNKGAR--EIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAEEVHAI
...||||| ||| ||||..|.|||.||...|. . ..|. .. .||.|| | | | .|..|| .|..| . .
lpgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvqtleqyrfvyealleylklk
|
|||||||||
subfamily_PTPN13_pd | Subfamily PTPN13 | 960-1220 | 2.2e-54 | 179.6 | In-house | 13-267 (273) | alignment | ||
Range on Protein: 960-1220
Range on HMM: 13-267/273.0
LQREWEALCRYEAEPSAREAASQpQCAGLNRPGAPLPYDHSRVVLNHLANaegldYVNASTIT-DHDPRAPAYVAAQGPLPSTLAHFWQMIWEQGAVVIV
. |.. | . ..... .. . || ||||..|| |. .. |.||| | . |.|.||||| | . ||||.||| | ||.
Paeefkelrelkpldtcevgkkk.enkdknryrnvlPydetrvklgdegg.....yinaslikvpvgkdeyeyiacqGPlPetvkdfwqmvweqkaevia
ALCRLQENGEVACARYWPEEGAEVYHIYE---VHLVSeHIWCDDYLVRSFYLKNLRTSETRTVTQFHFLSWPHMGVPAQAKALLDFRRKVNKSYRgrRSC
. .|.|.| | |||||. . ... |.|. |.. ||.. .|.....|.| |....| .|| |||..|. || | ..|.. . .
mvtlekekgkvkchrywPesknkklkvsnrlevellk.vqkldgfvvralavkdsesgesrevahlnfvkwPdhgvPssaaellqfvaevrrlqt..dag
PIVVHGSAGAGRTGVYILLDLVLERMNKGArEIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAE
||||| ||| ||.|..| .| ||. ... |.|. ....||.|| ||| |..|. || |. |
PivvhcsaGiGrsGtlitidvvlglierdk.efdvkeivrklreqrqgvvqtkdqyifvykaile
|
|||||||||
DSPc_SM00195 | 961-1221 | 1.8e-70 | 232.7 | In-house | 3-261 (263) | alignment | |||
Range on Protein: 961-1221
Range on HMM: 3-261/263.0
QREWEALCRYEAEPsAREAASQPQCAGLNRPGAPLPYDHSRVVLNHLANAEGLDYVNASTITDHdPRAPAYVAAQGPLPSTLAHFWQMIWEQGAVVIVAL
..| | | ... . . | ... || |||||.|| |.. . || ||.||. |. . . .|.|.|||||||...||.|.||.. .|| |
keefekleestspk.etteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikga.nkkkkyIatQgPlpstvedFWrmvweekvkiivml
CRLQENGEVACARYWPEE--GAEVYHIYEVHLVSEHIWCDDYLVRSFYLKNLRTSETRTVTQFHFLSWPHMGVPAQAKALLDFRRKVNKSYRGRrSCPIV
.. .|||. |.|||||| | |... ..|.||.... |.. .| . |.. ..|||.|||... .||. ||| ..| .|.. |.|.||.. | |||
teeeengkekcdrywpeesggketfgkisvklvevekkkdeiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkksksts.sgpiv
VHGSAGAGRTGVYILLDLVLERMNKGAReIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAEE
|| ||| ||||.....|..|...... . .|| .....||.||.|.| |..|. |. .|..|
VhCsaGvgRtgtfvtidiilskleeekk.vdifeivkelRkqRpgmvqtleqYlfiyeailey
|
|||||||||
PTPc_SM00194 | 961-1221 | 1.8e-70 | 232.7 | In-house | 3-261 (263) | alignment | |||
Range on Protein: 961-1221
Range on HMM: 3-261/263.0
QREWEALCRYEAEPsAREAASQPQCAGLNRPGAPLPYDHSRVVLNHLANAEGLDYVNASTITDHdPRAPAYVAAQGPLPSTLAHFWQMIWEQGAVVIVAL
..| | | ... . . | ... || |||||.|| |.. . || ||.||. |. . . .|.|.|||||||...||.|.||.. .|| |
keefekleestspk.etteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikga.nkkkkyIatQgPlpstvedFWrmvweekvkiivml
CRLQENGEVACARYWPEE--GAEVYHIYEVHLVSEHIWCDDYLVRSFYLKNLRTSETRTVTQFHFLSWPHMGVPAQAKALLDFRRKVNKSYRGRrSCPIV
.. .|||. |.|||||| | |... ..|.||.... |.. .| . |.. ..|||.|||... .||. ||| ..| .|.. |.|.||.. | |||
teeeengkekcdrywpeesggketfgkisvklvevekkkdeiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkksksts.sgpiv
VHGSAGAGRTGVYILLDLVLERMNKGAReIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAEE
|| ||| ||||.....|..|...... . .|| .....||.||.|.| |..|. |. .|..|
VhCsaGvgRtgtfvtidiilskleeekk.vdifeivkelRkqRpgmvqtleqYlfiyeailey
|
|||||||||
subfamily_Cele-PTP-18_pd | Subfamily Cele-PTP-18 | 961-1215 | 5.1e-24 | 79.5 | In-house | 25-280 (305) | alignment | ||
Range on Protein: 961-1215
Range on HMM: 25-280/305.0
QREWEALCRYEAEpSAREAASQPQCAGLNRPGAPLPYDHSRVVLnhlANAEGLDYVNASTITDhDPRAPAYVAAQGPLPSTLAHFWQMIWEQGAVVIVAL
. |. |. |.. .| . | || || |. || | .. .|. | .. . .. .| || | | || | ... | |
raefvamkrfndf.ekmkafkeaqeagknrykdvgcldnnrvkl...egpwpheyihanyvst.ptnpkrfictqaplektcadfwymclqdkveaifml
CRLQENGEVACARYWPEEGAEVYHIYEVH-LV-----SE-HI----WCDDYLVRSFYLKNLRTSETRTVTQFHFLSWPHMGVPAQAKALLDFRRKVNKSy
| |.| | |. |.. . .| .. | . | . .. . .. . . ...| ||..|. || |||| |.|.. | |
cnllekgakkcleyfaskdkdvlefeekgqkisvkfessvtlkfrkdakakvtetvlviegpgekarkvthyhwidwpdrgvpaadlailellekarps.
RGrrscPIVVHGSAGAGRTGVYILLDLVLERMNKGAREIDIAATLEHLRDQRAGVVATRQQFEFVL
.| ||||| ||| |||| ..|. .|... | | | ..|.|| . | .|. ||
kg....pivvhcsagigrtgsvvmleyildqllagqiiedtdkilqkireqrnnsiqtdaqylfvh
|
|||||||||
subfamily_PTPN1_pd | Subfamily PTPN1 | 962-1227 | 5.6e-59 | 194.2 | In-house | 6-276 (290) | alignment | ||
Range on Protein: 962-1227
Range on HMM: 6-276/290.0
REWEALC---RYEAEPSAREAASQPQCAGLNRPGAPLPYDHSRVVLNHLANaeglDYVNASTItDHDPRAPAYVAAQGPLPSTLAHFWQMIWEQGAVVIV
| ..... | ||. ..| .|. .||| ||||||..|.. | ||.||| . . . |. .|||||.| .|||||.||| . .|
rlykeiyldirkeasdfptreaklpenrnlnryrdvspydhsrikleradn....dyinaslv.eleeakrsyiltqGPlpntvdhfWqmvWeqkskavv
ALCRLQENGEVACARYWPEEGA--EVYH---IYEVHLVSEHIwCDDYLVRSFYLKNLRTSETRTVTQFHFLSWPHMGVPAQAKALLDFRRKVNKSYR-GR
| .. |.... ||.|||.. |. ..|.|.||.. . | || . |.||.| |||....||...|| .||| |.|.| || .| .
mlnkvvekeqikcaqywPqgeeekellledtklkvkliseer.ksyytvrllelenlktqetreilhfhyttwpdfgvpespaaflkflfkvresGslss
RSCPIVVHGSAGAGRTGVYILLDLVLERMNKGAR--EIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAEEVHAILK
| |.| ||| ||.| ..|.| .| ...| .|| .| .|| .| |.. | .|..| .|. | .. | .
dvGpavihcsaGiGrsGtfclvdtclvliekkddlssvdikkvllelrkyrlGliqtadqlrfsylaileGakvikg
|
|||||||||
subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 963-1221 | 6.6e-58 | 191.5 | In-house | 3-254 (284) | alignment | ||
Range on Protein: 963-1221
Range on HMM: 3-254/284.0
EWEALCRYEAEPSAREAASQPQCAGLNRPGAPLPYDHSRVVLNHLANAEGLDYVNASTITDHDpRAPAYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCr
|. ..|. .. . .. | .| || | |..|...| |..| |. ||.||| || . | |.|.||||. ||| ||.||||. . || |
efrracklgvngtdqtfanldqnkdknrighilafdknvvklerliGeefsdyinasfitGyq.rkdkyiatqGPldntladfWrmiweyncstivllt.
lqengEVACARYWPEEGAEVYHIYEVHLVSEHiWCDDYLVRSFYLKN-LRTSETRTVTQFHFLSWPHMGVPAQAKALLDFRRKVNKS-YRGRRSCPIVVH
. |..||| .. . .. ..|.. | . ...| ||.. | . . . |...||||| ||..||| .. |. . .||.. . . .||||
.....kdkcsqywplkivikeerfkvkvdsve.eseeyvvrdielsedgkekdirkirqfhflgwpdvgvpdypsdlmrlvkkvrhltskenhranivvh
GSAGAGRTGVYILLDLVLERMNKgAREIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAEE
|||.||||||| || .|.||.. . .|. ... ||.|| .| |. |. .|. ||
csagvgrtgvyivldvlldrmke.ekqvdvynfvrdlrqqrntlvqdlvqykfiysallee
|
|||||||||
subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 963-1224 | 2.3e-49 | 162.9 | In-house | 25-280 (287) | alignment | ||
Range on Protein: 963-1224
Range on HMM: 25-280/287.0
EWEALCRYEAEPSAREAASQPQCAGLNRPGAPLPYDHSRVVLNhlanAEGLDYVNASTITDHDpRAPAYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCR
. | . . .. . .| .|| |..| ||.|. | ||.||. | . . |...|..|. .|. ||..|... .|| ||.
qftvleqvtqredevthniasqnkdknRltqilvpdnyrvllk....gehpdyinavfidgyk.ekkafiiaesPmfntarnfWkliddrnvtaivmlcq
LQENGEVACARYWPEEGAEVYHIYEVHLVSEHiWCDDYLVRSFYLKNLR-TSETRTVTQFHFLSWPHMG-VPAQAKALLDFRRKVNKSYRgRRSCPIVVH
..|| | .| .||||| . |. |...|..|. ..|..| . .|| ......|.|... .|. | |. .. || . ... . .. | .||||
ekendeevcyqyWpeeksvvlGeyniellnee.vnagyierklevknknkagdkqqvkqyqitnWdstgkvtepqtillvieemyktqrk.rgntsivvh
GSAGAGRTGVYILLDLVLERMNKGArEIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAEEVHA
|.. ||..... . ... .. ||. |.. | |. | | | .|..|. .| | ...
CsdtvGrsamfcaaattinkckteG.viDvfqvlksqriqkpgsvqtveqykfindivleylds
|
|||||||||
subfamily_Sponge-PTP5_pd | Subfamily Sponge-PTP5 | 968-1221 | 2.5e-41 | 136.4 | In-house | 16-265 (283) | alignment | ||
Range on Protein: 968-1221
Range on HMM: 16-265/283.0
CRYEAEPSAREAASQPQCAGLNRPGAPLPYDHSRVVLNHLANaeglDYVNASTIT--DHDPRAPAYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCRLQE
| . . || . || .|.| || |. ... ||.||. |. ... . |..||.|| | ||.|.... .. || | .|||
krlsvpdldadiasadenkrknrnqeivpadqwrvelksesr....dyinavfipvsksykqdkkyiiaqsPldrtvvdfWkmvfdekitaivmltklqe
NGEVACARYWPEEGAEVYHIYEVHLVSEhIWCDDYLVRSFYLKNL-RTSETRTVTQFHFLSWPHMGVPAQAKALLDFRrKVNKSYRGRRSCPIVVHGSAG
. ...|..|||..|.| | . | | | . . .. . |.. . .| .. . . | ..| | .|. | || . . ||||| |.|
dlrikCsqyWPkrGsedyGeftvtlrke.ttsnsfiikelllrvnssakstlllahyqvidWleygeqaiinslvkfn.kvislqteskkgPivvhCstg
AGRTGVYILLDLVLERMnKGAREIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAEE
|||.|.| . .. . . .|. |... .| || ..| |..|. .| .| |.
iGrtavfiaasasvkda.ltesvvdvfavvkimreqrmmavqtldqyklvhelvleq
|
|||||||||
subfamily_PTPRK_pd | Subfamily PTPRK | 969-1223 | 1.6e-58 | 193.0 | In-house | 27-278 (314) | alignment | ||
Range on Protein: 969-1223
Range on HMM: 27-278/314.0
RYEAEPSAREAASQPQCAGLNRPGAPLPYDHSRVVLNHLANAEGLDYVNASTItDHDPRAPAYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCRLQENGE
||. . .|| . . || | |.||.|||.| . . ||.||. | | |. |....||||..|.. ||........ || | |.|.|
eyeslfegwdaakkdenreknrsgdilaydrsrvflitidgdpssdyinaali.dsykrpaafivtqgPlqetvkdfWrlvydencasivmltelvevgr
VACARYWPEEGAEvYHIYEVHLVSEHIWCdDYLVRSFYLKN--LRTSETRTVTQFHFLSWPHMGVPAQAKALLDFRRKVNKSYRGrRSCPIVVHGSAGAG
| | .||||.. | .|.||. .. . ...|| | ... .|.|.| ||.||.||. .|| .|..||.. |.|.|| . .|||| |||||
vkClkyWPedtev.ygdikvelvetella.elvvrifrveklargqeeirevrqfqflgWpdhdvPvsatgllklvrrvkksqee.eaGrivvhCsaGaG
RTGVYILLDLVLErMNKGAREIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAEEVH
|||..| .| ||. | . . .|. . ||... .| | .|. |. .. | .
rtGtfiaidivld.mieregvvdvfnavktlrsrkvnmveteeqykfiydvileacl
|
|||||||||
subfamily_PTPN12_pd | Subfamily PTPN12 | 971-1230 | 4.5e-67 | 221.0 | In-house | 25-285 (290) | alignment | ||
Range on Protein: 971-1230
Range on HMM: 25-285/290.0
EAEP-SAREAASQPQCAGLNRPGAPLPYDHSRVVLNHLANAEGLDYVNASTITDHDpRAPAYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCRLQENGEV
|| .||..... || ||||.|||.|.. . || ||.||. | . .|.||||||| || ||.||||. ..| .||. |.|
kaekvysteagekeenvkknrykDilPydksrvelskieeeegsdYinanfikgve.gkleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkk
ACARYWPEEGAE-V-YHIYEVHLVSEHIWCDDYLVRSFYLKNLrtSETRTVTQFHFLSWPHMGVPAQAKALLDFRRKVNKsYRGRRSCPIVVHGSAGAGR
|.||||||| | . . .|| | .|. ||.|.|.. ... .|.|.|.|||. .|| |||..|| ||.. ..|.. .. . . |.||| ||| ||
kCerYWpeegeeelefgefevtleeekavdddflirtLkveaq..kesrkvyqfhYtaWPDhgvPssaksllelielvre.lqesedaPlvvhCsaGvGr
TGVYILLDLVLERMNKGAR--EIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAEEVHAILKALP
||. | .|.| | .... |.|. . .|| ||| .| |..|.|.| .|||| |.. |....
tGtiiaidyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavaelvqkeleiie
|
|||||||||
subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 971-1222 | 9.7e-37 | 121.4 | In-house | 19-295 (297) | alignment | ||
Range on Protein: 971-1222
Range on HMM: 19-295/297.0
EAEPSAREAASQPQCAGLNRPGAPLPYDHSRVVLNHlaNAEGLDYVNASTITDHDPRAP-AYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCRLQENGEV
||.. . .| .. . || | .| .|| | . ||.|| .. | |. |. ||||| .|. ||....||. ||| ...|||.|
eargesfssakrnsslrknryrdilatddtrvkllr..viterdyinadyvvfpdeeadlkyilaqGplsatvddfwtlvaeqdvrvivmvaklqedGrd
ACARYWPEEGAEVYHIYEVhlVSEHI--WCDDYL-VRSFYLKNLRTSETRTVTQFHFLSWPHMGVPAQAKALLDFRR--------------KVN------
|| |||. | . .| | |.. |.. | |. . ||.| |. ||||| |||.. . | |. |.
kcapywpsvvqerlkagdv..vveflsstsdefdrviltelqliyrsesrvvrhvqflswpdhGvpsdledlvrfqaqvcscciavpmmlalvemftamv
----KSYRG--RRSCPIVVHGSAGAGRTGVYILLDLVLERMNKGaREIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAEEV
.|.| |. ...|| ||| ||.|| .| | .|... |. | |.|| |..||.||| .| | .|||.. || . .
flqleslraemprnayllvhcsaGvGrsGvvvlsdvilaklrkk.ripdvaailsilreqrarlvqtleqfellydavlkkl
|
|||||||||
subfamily_ptpA1_pd | Subfamily ptpA1 | 971-1204 | 1.9e-32 | 107.5 | In-house | 33-278 (418) | alignment | ||
Range on Protein: 971-1204
Range on HMM: 33-278/418.0
EAEPSAREAASQPQCAGLNRPGAPLPYDHSRVVLNHLANAEGLDYVNASTITDHDPRapAYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCRLQENGEVA
|| . . . || || .|.|| |... . || ||.|| | |. ....||||| |.| ||.|.||. . .|| | | || .
svgpsetsegdkkhntsknrytnilpvnhtrvqlkkiqdkegsdyinanyidgaypk..qfictqgplpntiadfwrmvwenrcriivmlsresencrik
CARYWPEE-----------GAEVYHIYEVHLVsEHIWCDDYLVRSFYLKNLRTSETRTVTQFHFLSWPHMGVPAQAKALLDFRRKV----NK-SYRGRRS
| |||||. | ||. | | || | | . . . .. ||| .||... || .| ... . .. . . |. |
cdrywpeqiggeqfsiygngnevfgtysvelv.eviqdpereiitrnirltfegetrditqyqyegwpdhnipdhtqpfrqllhsitnrqnqiipssdrn
CPIVVHGSAGAGRTGVYILLDLVLERMNKGAREIDiAATLEHLRDQRAGV
||.|| ||| |||| . ........ ...| |. .... | . .
vpiivhcsagvgrtgtfctavimmkkldhyfkqld.atpidqvvdpfthl
|
|||||||||
subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 972-1223 | 2.3e-47 | 156.7 | In-house | 35-289 (325) | alignment | ||
Range on Protein: 972-1223
Range on HMM: 35-289/325.0
AEPSAREAASQPQCAGLNRPGAPLPYDHSRVVLNHLANAEGLDYVNASTITDHDpRAPAYVAAQGPLPSTLAHFWQMI--WEqgAVVIVALCRLqENGEV
.. |...| .|. || ...|.|||||. . .. ||.||| . |. . ..||| ||..|. .|... |. . |.| | | ..|.
ddgiakkvamkpenkaknrfknvvaldksrvvletkkddpssdyinasylrddk.kkdvflaaqaPltatindlWrlvldWr..csvvvvlnel.dlgkd
ACARYWPEE--GAEVYHIYEVHLVSEHIWcDDYLVRSFYLKNLRTSETRTVTQFHFLSWPHMGVPAQAKALLDFRRKVNKS---YRG--RRSCPIVVHGS
|| |||.| . . ||.|.. ||. | . .|. . |||.| ||.. ||. |||. . .|. . . |.. . . | ||.|| |
rcavywpkemgksktfGglevklrtieei.sdyvhrvldvkqvkkGetrsvkqfqlqswddmGvqkrpatlisilqlvkavservtantkastpilvhcs
AGAGRTGVYILLDLVLERMNKGAReIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAEEVH
|| |||||.| | .|... . .| .|| ...|| .| .| | |. .. |..| .
aGvGrtGvfislysalakvieesr.vdifgfvkklrkdrpsmvetvdqyiliyealveaym
|
|||||||||
subfamily_Sponge-PTP4_pd | Subfamily Sponge-PTP4 | 972-1078 | 1.3e-11 | 38.6 | In-house | 83-181 (244) | alignment | ||
Range on Protein: 972-1078
Range on HMM: 83-181/244.0
AEPSAREAASQPQCAGLNRPGAPLPYDHSRVVLNHlaNAEGLDYVNASTITDHdPRAPAYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCRLQENGEvac
.|| . | .|. . || || ||.| .|| |.. . | |.||| . |. |. .| || | ||.|. |. |.| | ..|. |
pdpsvmkdafnpnnswknregaglpfdfnrvplsk..gsmgntyinasfvgcl.grtaeyiltqhpladtsmdfwkmmlerhvnvlvvlgsveeede...
arYWPEE
|||.
..ywpds
|
|||||||||
0045098 | (Phosphotyrosine protein) phosphatases II | 973-1223 | 4.3e-68 | 225.0 | In-house | 21-273 (278) | alignment | ||
Range on Protein: 973-1223
Range on HMM: 21-273/278.0
EPSAREAASQPQCAGLNRPGAPLPYDHSRVVlnhlanaeglDYVNASTITDHdPraPAYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCRLQENGEVACA
|| . | . .. .|| ||||||||. ||.||| |. . | ....|.|||||||.|.||.|.||.| ||| |..|.|.| . ||
ipseitpalylgnldknRykdilpydhsrVk..........dYINAsyidgy.p..kkfIatqgPlpstvadfwrmlwelgitvivmltelvelgrekca
RYWPEEGAEVYHIYEVHLVSEHIWcDDYLVRSFYLKNL----RTSETRTVTQFHFLSWPHMGVPAQA--KALLDFRRKVNKSYR------------GRRS
.||||.| ..|. ..|.|.||... ||| .| ... || . |.|.||..|.|.|| .||| . | .|.. . ... .. ..
qywpeggsltygdftvtllseevl.ddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllsslllldsg
CPIVVHGSAGAGRTGVYILLDLVLERMnkGaREIDIAATLEHLRDQRAG-VVATRQQFEFVLMAVAEEVH
.|..|| ||| ||||......|.||.. . . .|. ....|| || | .| . .|..|. ....| ..
gpvlVHCsaGvgRtGtlvaaylmlell..e.ggvdlleavkelrsqRpglavqnleqyrflyefllelll
|
|||||||||
subfamily_PTPRA_pd | Subfamily PTPRA | 975-1220 | 7.6e-63 | 207.4 | In-house | 48-293 (330) | alignment | ||
Range on Protein: 975-1220
Range on HMM: 48-293/330.0
SAREAASQPQCAGLNRPGAPLPYDHSRVVLNHLANAEGLDYVNASTITDHDPRaPAYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCRLQENGEVACARY
.. |.||. . || ||||.|||.|... | ||.||| | . . ..|||||. |. ||.||||| . || | |.| | ||.|
atlelaskeenkeknrvvnilPydfsrvilsvkeGveesdyinasfidGykek.dkfiaaqGPkeetvedfwrmiweqksativmltelkerkeekcaqy
WPEEGAEVYHIYEVHlVSEHIWCDDYLVRSFYLK----NLRTSETRTVTQFHFLSWPHMGVPAQAKALLDFRRKVNKSYRGRRScPIVVHGSAGAGRTGV
||.||. | |. | .. . || || | .. . | ..| |.|||| |||..|||.... .|.. .||.| . . ||||| |||.||||
wPdeGlvtyGnirve.vedetvlvdytvrkflvqqlpdatrekksrlvrqfhftswPdvGvPfepiGmlkllkkvkklnqqsag.pivvhcsaGvGrtGt
YILLDLVLERMnKGAREIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAE
.| || ||||. | | .|. ....|| ||. .| | .|.||. .. |
fivldavlerv.kaerkvdvfefvkrlrlqrpqmvqtdeqyefiykvlle
|
|||||||||
subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 975-1224 | 8.5e-54 | 177.5 | In-house | 34-279 (315) | alignment | ||
Range on Protein: 975-1224
Range on HMM: 34-279/315.0
SAREAASQPQCAGLNRPGAPLPYDHSRVVLNHLANAEGLDYVNASTITDHDPrAPAYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCRLQENGEVACARY
. . .| ... || . ||.|..||.|. . . ||.||| | | ||.|.||||.... ||.|.... . || . .||. . |..|
yrqrvaretinfkknryknilPldsarvkleviddsPdsdyinasyiksvdd.dkayiasqgPlkasvddfwrmvlqekvttivmvtkkqegdkikcrqy
WPEEGAEV--YHIYEVHLVSEHiWCDDYLVRSFYLKNlrTSETRTVTQFHFLSWPHMGVPAQAKALLDFRRKVNKSyRGRRSCPIVVHGSAGAGRTGVYI
||.. |. . ..|.|.| . . | .| . ... . |.||||||.| ||. ||. |. .|| . ..| . .|.. ...|| |||.||||| |
wPdrkadsvefGsikvellsle.adtdgvarklvtrk..seesrtvtqfqftewPdkGvdkqtssllklikevkad.ngkkefsllvhcsaGvGrtGvvi
LLDLVLERMNKgAREIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAEEVHA
.| |...... .| .|. ... ||..| .| |.... |. || |...
sidevvaqikr.trsvdvfnfvknlrakrpylvqteeeyafiydavledllw
|
|||||||||
subfamily_Urchin-PTP-4_pd | Subfamily Urchin-PTP-4 | 978-1222 | 2.6e-39 | 129.7 | In-house | 38-236 (392) | alignment | ||
Range on Protein: 978-1222
Range on HMM: 38-236/392.0
EAASQPQCAGLNRPGAPLPYDHSRVVLNHLANAEGLDYVNASTITDHDPRaPAYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCRLQENGevacarywpe
.| .. || . |||| .||.|. . . ||.||| | | ||.|.||| ...| ||.|.... . |. . .|.|
tvaqkeinlkknryknilpydsarvkleviddipdsdylnasyipsfdne.kayiasqgpnaaslddfwrmvfqenvttiamvtklkegd..........
egaevyhiyevhlvsehiwcddylvrsfylknlRTSETRTVTQFHFLSWPHMGVPAQAKALLDFRRKVNKSYrGRRSCPIVVHGSAGAGRTGVYILLDLV
. ..|||.|||| || .|| .. .|| | ..|. . |. . |...| ||| ||||| | .| |
.................................kgddartvaqfhftewPdkdvpkhtssllkfikevkadf.Gqythpliihcsagvgrtgvvisidsv
LERmNKGAREIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAEEV
. . | .| .|. . .| .| .| |..|. |. || |..
vah.akktrmvdvfnfvtnirrkrpymvqtkeqyafiygavledl
|
|||||||||
subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 980-1223 | 8.4e-62 | 203.6 | In-house | 4-243 (250) | alignment | ||
Range on Protein: 980-1223
Range on HMM: 4-243/250.0
ASQPQCAGLNRPGAPLPYDHSRVVLNHLANAEGLDYVNASTITDHDPRaPAYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCRLQENGEVaCARYWPEEG
| .|| || ...|.|||||.. . ||.||| . .| | |..|.||||..|. .||.|..|. . .|| | |.|.... . .||| |.
akkpqnkeknryadiialdssrvvLekekgdkesdyinasflhgyder.kafiatqgPlqatiedfWrmvleeksgtivmLtnLkesekt.yhqywPvek
AEVYHIYEVHLVSEHIWCdDYLVRSFYLKNLRTSETRTVTQFHFLSWPHMGVPAQAKALLDFRRKVNKSYRGRRSCPIVVHGSAGAGRTGVYILLDLVLE
|| | |.| |.... || .| . | . . .. |.| |.||..|| |||..|.| |....||..| . . |..|. ||| ||.| .| .| |||
aekyGdvtvsllskeefa.dytkrklklskakkaderivrqlhfvvWPdkgvPevatavLellkkvqasqqqagnaPvivqCsaGvgrsGafiaidavle
RMNKgAREIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAEEVH
|..| . .|. .. || .| ..| ...|. || ... . .
rlkk.ekvvdvfkvikvlrkdrphavesleqyvfvyeiilkald
|
|||||||||
0049772 | (Phosphotyrosine protein) phosphatases II | 981-1222 | 3.5e-29 | 97.9 | In-house | 42-280 (314) | alignment | ||
Range on Protein: 981-1222
Range on HMM: 42-280/314.0
SQPQCAGLNRPGAPLPYDhSRVVLnHLANAEGLDYVNASTITDHdpraPAYVAAQGPLPSTLAHF----------WQMI--WEQGAVVIVA---------
... || ||.| .||.| . . .| || ||| . . ...|.||||. |. | |.|. ... .||
dlflnrdknryldilpad.nrvil.pglpvsgsdyinasyvdgf....lkfIatqgpleitvvdfreepvlyyngwrmvlrgdlnvrdivmsrdevlade
------------LCRLQENGevacaRYWPEEGAEVYHiyevhlvsehiwC-----DDYlvrsfylknlrtseTRTVTQFHFLSWPHMGVPaQAKALLDFR
|..| .|| ..... | .. ... .|.. ... . .| ..| . ...|
lsrLdaAlgKtpllildgng.....neptaadlellk............eelydpelf..............erlgikylripvpDgsap.lledfdefl
RKVNKSyrgRRSCPIVVHGSAGAGRTGVYILLDLVLERMNkgareIDIAATLEHLRDQRA-----GVVATRQQFEFVLMAVAEEV
. ... .. |..|| .|| ||||......... ... .... .||..| .| | . . .|.||.|.|. | .
efieea...dkggpvlvHCkaGkgRtgtfvvaaylmkllg.....vsleealedvrlkRpinpnpgfieqleqyefilealleyl
|
|||||||||
subfamily_Sponge-PTP9_pd | Subfamily Sponge-PTP9 | 982-1219 | 4.1e-33 | 109.4 | In-house | 37-290 (301) | alignment | ||
Range on Protein: 982-1219
Range on HMM: 37-290/301.0
QPQCAGLNRPGAPLPYDHSRVVLNHLAN--AEGLDYVNASTITDHDpRAPAYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCRLQENGEVACARYWPEEG
. . . ||| .||. |..|.. | .|.||| | . .. ...|||||. .||. ||..||.. | || .. |.|. . | .|||.
seenkalnrfknitvyddnriilkpkpnldlcqreyinasyidgys.ekkkfiaaqgpmkktlvdfWrliwqekpvsivmvtnlkegtkskceqywpnse
AEVYHIYEVH-LVSEHIWCDDYLVRSFYLKNL---------------RTSETRTVTQFHFLSWPHMGVPAQAKALLDFRRKVNKSYRGRRSCPIVVHGSA
|| .. .... ..... |...|.. .| .. ....|.|.. .||. || . . | .| . . |.||| |.
aeseefgpftvtlvneqvyPdfvirqlnvkiqdgsnngyierkfkvksdksswdvlqlqvtdWpqdGvvreprtvLqviddvihrqqkigggpvvVHCSd
GAGRTGVYILLDLVLERMnKGAREIDIAATLEHLRDQRAGVVATRQQFEFVLMAVA
. .|.|||. ... || | .|. . .| .. |.| | .|. .. ..
tVsrsGvYcsvsiglEQc.kaegVVdvfqvtkavrrskpgaVtTLeqytsiydvid
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 983-1148 | 3.5e-27 | 89.9 | In-house | 26-193 (319) | alignment | ||
Range on Protein: 983-1148
Range on HMM: 26-193/319.0
PQCAGLNRPGAPLPYDHSRVVLNHLANAEGLDYVNASTITDHDPRAPAYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCRLQENGEVACARYWPEE----
. . .| .| ..||||.. .. . |..|| . .| |.||| .| .. . ||...||| . ||| |. |.|.| ||.|.| .
vtskdksrvinvvPlPetrvvlqrigdddkdeyldasyvrGyddapnsyiaaqvsledsssdfwrtvweqqsrvivqltdlselGikvcaeylPtketld
GAEVYHIYEVHLVSEHiWCDDYLVRSFYLKNLRTSETRTVTQFHFlSWPHMGVPAQAKALLDFRRKVNKS
. ..| . | | | |.. .. ||.. .|.| .| . . |.. .|||. .||. .|..|
ntslyGdilvtlkgre.vkdryaistlllkrvdkeesrelthywy.kwleaevPaeeaaliamllevrss
|
|||||||||
0040439 | (Phosphotyrosine protein) phosphatases II | 986-1220 | 2e-66 | 219.5 | In-house | 12-244 (249) | alignment | ||
Range on Protein: 986-1220
Range on HMM: 12-244/249.0
AGLNRPGAPLPYDHSRVVLNHLANAEGLDYVNASTItDHDPRAPAYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCRLQENGEVACARYWPEEGAEVYHI
.|| ||||||||.|..| . .. ||.||| | | . ....|.|||||.|...||.|.||.| ||| |..|.|.| . ||.|||..| .|.
kdknrypdilpydhsrvklsilpglflsdyinAsyi.dgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqywplggsleygd
YEVHLVSEHIwCDDYLVRSFYLKNLRTSETRTVTQFHFLSWPHMGVPAQAKALLDFRRKVNKSYRGR-RSCPIVVHGSAGAGRTGVYILLDLVLERMNKG
. |.|.|... .||| || ..|.|| ..|.|||.......||..||| . |||| ..|.| .. ...|..|| ||| ||||..|...|.||...|
ftvtllsvev.kddytvrtleltnlydgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtfiaaylmleqleke
aREIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAE
...|. ....||.|| |.| . .|..|...|..|
.lgvdleeavkllrsqRpgavqnpeqyrflyealle
|
|||||||||
subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 986-1224 | 4.2e-48 | 158.7 | In-house | 21-266 (270) | alignment | ||
Range on Protein: 986-1224
Range on HMM: 21-266/270.0
AGLNRPGAPLPYDHSRVVLNHLANAEGLDYVNASTITDHDPRAPAYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCRLQENGEVACARYWPEEGAE--VY
. ||| || ..||.|..| . . |.|| . | . .|.||.||||.|| .||.||||. . || . |.|.| |.||||.| | .
kklnRyadiLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpaepkekvkl
HIYEVHLVSEH-IWCDDYLVRSFYLKnlRTSETRTVTQFHFLSWPHMGVPAQAK------ALLDFRRKVNKSYRGR-RSCPIVVHGSAGAGRTGVYILLD
. ... .... . |... |. ...|.| .. |.. .|| ||| .. || |.| .| . .. |..|| ||| ||||. |.||
edgkikvlalseekeegyiltrlrle..ekgeerrlvHfwyntWpdhgvpreedsslstdqllkmlravrrsekeldkaePllvHcsaGvgRtGtlialD
LVLERMNKGaREIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAEEVHA
... ... ...|..| .|.|| .| .| . .|.||. ||.| ..
iavrlLeet.kkvdvlaiieelRkdRmalvqhpeqyeflykavveyaer
|
|||||||||
subfamily_CG7180_pd | Subfamily CG7180 | 986-1221 | 3.1e-41 | 136.0 | In-house | 43-289 (296) | alignment | ||
Range on Protein: 986-1221
Range on HMM: 43-289/296.0
AGLNRPGAPLPYDHSRVVLNHLANAEGLDYVNASTITDHdPRAPAYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCRLQENGEvACARYWPEEGAEVYHI
. || .|||. ||||..| | ||.||. . . . .|. ..| .|. ||........ .| |.. . . . |||... | |
reknrdvkvvPyDynRvvLekldGeeksdYinavyvdsf.lkkkeyivteapkketvdefWrlvydeeisavvvLtktfdfak.mypsywpnkskeqyge
YEVHLVSEHIWCDdYLVRSFYLKNL----------RTSETRTVTQFHFLSWPH-MGVPAQAKALLDFRRKVNkSYRGRR-----SCPIVVHGSAGAGRTG
.|..|.|. . . | | |. . |||.|..|.. |. || ..||...||.|. ..|.. |.||. | ||.|.|
ifveiveekqyan.lkirtfkltkkivalteqekqvkaetRivklfqlteWeledkvPlstnalielrrrvr.lwrekvdedpeegPvvvvssdGasRsG
VYILLDLVLERMNKgAREIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAEE
||. .| || ..| |.|. . || .| ..| . ... .. . |
vylaidanlelvek.eeevdvFeavktlrrsRpqLvenveeYkyiYdvllea
|
|||||||||
0042113 | (Phosphotyrosine protein) phosphatases II | 987-1220 | 4.2e-66 | 218.1 | In-house | 11-241 (245) | alignment | ||
Range on Protein: 987-1220
Range on HMM: 11-241/245.0
GLNRPGAPLPYDHSRVVLNHLANAEGLDYVNASTItDHDPRAPAYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCRLQENGEVACARYWPEEGAEVYHIY
.|| .|||||.||.|.. . ...||.||| . | . . | . |.|||||.|...||.|.||.| .|| |... |.| | ||.|||... .|. .
dknrysdilpydhtrvklspdggdldsdyinasyv.dgyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywplgesltygdf
EVHLVSEHIwCDDYLVRSFYLKNLRTSETRTVTQFHFLSWPHMGVPAQAKALLDFRRKVNKSYRGRRSCPIVVHGSAGAGRTGVYILLDLVLERMNKGaR
|.|.||.. .||| || . ..||...|.|.|...|.|.||..||| . |||| . |.| .. .. |..|| ||| ||||..|...|.||...| .
tvtllseeh.lddytvrtlevtnlgddesrevihyhylpwpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylmleqleke.l
EIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAE
.... ....||.|| |.| | .|..|. .|..|
gvsleeavkelrsqRpgavqtpsqyrflyealle
|
|||||||||
0037934 | (Phosphotyrosine protein) phosphatases II | 988-1220 | 2.5e-59 | 196.1 | In-house | 13-240 (243) | alignment | ||
Range on Protein: 988-1220
Range on HMM: 13-240/243.0
LNRPGAPLPYDHSRVVLnhlanaEGLDYVNASTITDHdPRapaYVAAQGPLPSTLAH----FWQMIWEQGAVVIVALCRLQENGEVACARYWPeE-GaeV
|| ||||||||.| || ||.||. |. || . | |||||.|... ||.|.||.| ||| |..|.|.| . ||.||| . .
knrysdilpydhsrvkl......egsdyinanliyvt.pr...liatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqywp.gev..t
YHIYEVHLVSEHIwCDDYLVRSFYLKNLR-TSETRTVTQFHFLSWPHMGVPAQAKALLDFRRKVNKSYRG-------RRSCPIVVHGSAGAGRTGVYILL
|. ..|.|.||. .||| || ..|.|| . .||.|...|.|.||..||| . |||| ..|.. .. .. |..|| ||| ||||..|..
ygdftvtllseeh.lddytvrtlllenldlddltrlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgRtGtliaa
DLVLERMnkgarEIDIAATLEHLRDQRAG-VVATRQQFEFVLMAVAE
.|.|... ..|. ....||.|| | .| |..|..|. .|..|
ylmllll.....gvdleeavkllreqRpgkavqtpsqyrflyealle
|
|||||||||
0041856 | (Phosphotyrosine protein) phosphatases II | 988-1222 | 6.6e-38 | 125.5 | In-house | 4-171 (182) | alignment | ||
Range on Protein: 988-1222
Range on HMM: 4-171/182.0
LNRPGAPLPYDHSRvvlnhlanaeGLDYVNASTITDHDPRAPaYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCrlqengevaCARYWPeegaevyhiye
.|| ||||||| .|||.||. . | ..|.||||.||.|.|..|..|.| .|| |. . .|||
knrysdilpydhsr..........dldyInanlylgslpatr.fiatqgpllstvadflrmlkelgittivnlt.........eelywp...........
vhlvsehiwcddylvrsfylknlrTSETRTVTQFHFLSWPHMGVPAqAKALLDFRRKVNKsyrgrRSCPIVVHGSAGAGRTGVYILLDLVLERmnkgarE
. ..|...|...|.|| .||| |||| ..|.. ...|..|| ||| ||||......|.... .
........................ellerlgiqylylpwpDhgvpd.ldelldfieevle.....eggpvlVHCsaGvgRtgtlvaaylmkkl......g
IDIAATLEHLRDQRAGVVATRQQFEFVLMAVAEEV
... .....| .| |.| | .|. |. .|. |..
vsleeavklvrsrRpgmvitpnqyfflqlallell
|
|||||||||
subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 988-1085 | 2.2e-16 | 54.5 | In-house | 50-160 (350) | alignment | ||
Range on Protein: 988-1085
Range on HMM: 50-160/350.0
LNRPGAPLPYDHSRVVLNHLA--------NAEGLDYVNASTITDH---DPRAPA--YVAAQGPLPSTLAHFWQMIWEQGAVVIVALCRLQENGEVACARY
|| |||.|||| |.. .. ||.||. . | |.|.|.|||||. |...| . . ||..| ..|.. | ||
knrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvelnlekcyrY
WPEEGAEVYHI
|.| . . ...
Wqegsydditv
|
|||||||||
subfamily_Sponge-PTP-2_pd | Subfamily Sponge-PTP-2 | 988-1105 | 1.6e-08 | 27.7 | In-house | 30-111 (169) | alignment | ||
Range on Protein: 988-1105
Range on HMM: 30-111/169.0
LNRPGAPLPYDHSRVVLNHLANAEGLDYVNAstitdhdprapayvaaqgplpstlahfwQMIWEQGAVVIVALCRLQENgevacARYWPEEgaEVYHIYE
||| .|| | || |... . | ||.|| .|||| | ||| | .. .||| | | ..
knrpagplapshtrvklqrvmedlgsdyina............................rmiwetnasvivvlgdtddk.....nnfwpek..edyqlhp
VHLVSEHiWCDDYLVRSF
.. | . | ||.
avilgew.ytdslyvrtd
|
|||||||||
subfamily_Sponge-PTP2_pd | Subfamily Sponge-PTP2 | 988-1105 | 2e-08 | 27.3 | In-house | 29-110 (169) | alignment | ||
Range on Protein: 988-1105
Range on HMM: 29-110/169.0
LNRPGAPLPYDHSRVVLNHLANAEGLDYVNAstitdhdprapayvaaqgplpstlahfwQMIWEQGAVVIVALCRLQENgevacARYWPEEgaEVYHIYE
||| .|| | || |... . | ||.|| .|||| | ||| | .. .||| | | ..
knrpagplapshtrvklqrvmedlgsdyina............................rmiwetnasvivvlGdtddk.....nnfwpek..edyqlhp
VHLVSEHiWCDDYLVRSF
.. | . | ||.
avilGew.ytdslyvrtd
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 989-1220 | 1.8e-67 | 222.6 | Pfam-A | 5-235 (235) | alignment | ||
Range on Protein: 989-1220
Range on HMM: 5-235/235.0
NRPGAPLPYDHSRVVLNHLANAEGldYVNASTITDHDpRAPAYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCRLQENGEVACARYWP--EEGAEVYHIY
|| ||||..|| |.. ... |.||.... .. . ...|.||||.||...||.|.|.. ||| |..|.|.|...||.||| ||. . |. .
nRykdilpydktrvklkgsegpsd..YInAnyvkgyk.ekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeesltygdi
EVHLV-SEHIWCDDYLVRSFYLKNLRTS-ETRTVTQFHFLSWPHMGVPAQAKALLDFRRKVNKSYrGRRSCPIVVHGSAGAGRTGVYILLDLVLERMNKG
.|.|. .|. ....| .| . ||. .. |.|.|.|.|. .||. |||...|.|||. |||.|| .| |.||| |||.||||....||..||.....
kvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkveksk.eaksgpvvVhCsaGvgRtgtfvaldilleqleae
AReIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAE
.|. ....|| ||.|.| . .|..|. .|..|
ee.vdvlqivkelRkqRpgmvqsleqYiflykaile
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 989-1220 | 1.8e-67 | 222.6 | In-house | 5-235 (235) | alignment | ||
Range on Protein: 989-1220
Range on HMM: 5-235/235.0
NRPGAPLPYDHSRVVLNHLANAEGldYVNASTITDHDpRAPAYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCRLQENGEVACARYWP--EEGAEVYHIY
|| ||||..|| |.. ... |.||.... .. . ...|.||||.||...||.|.|.. ||| |..|.|.|...||.||| ||. . |. .
nRykdilpydktrvklkgsegpsd..YInAnyvkgyk.ekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeesltygdi
EVHLV-SEHIWCDDYLVRSFYLKNLRTS-ETRTVTQFHFLSWPHMGVPAQAKALLDFRRKVNKSYrGRRSCPIVVHGSAGAGRTGVYILLDLVLERMNKG
.|.|. .|. ....| .| . ||. .. |.|.|.|.|. .||. |||...|.|||. |||.|| .| |.||| |||.||||....||..||.....
kvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkveksk.eaksgpvvVhCsaGvgRtgtfvaldilleqleae
AReIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAE
.|. ....|| ||.|.| . .|..|. .|..|
ee.vdvlqivkelRkqRpgmvqsleqYiflykaile
|
|||||||||
subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 989-1223 | 1.9e-54 | 179.6 | In-house | 47-277 (515) | alignment | ||
Range on Protein: 989-1223
Range on HMM: 47-277/515.0
NRPGAPLPYDHSRVVLNHLANAEGLDYVNASTITDHDPrAPAYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCRLQENGEVACARYWPEEGAE-V-YHIY
|| . |||| .|| |. . .. ||.||| | | ||.|.|||..... ||...... |. . .|.|. . |..|||. .. | . .
nryknilPydsvrvklevindnPhsdyfnasyipsfdn.dkayiasqgPnkasvddfWrlvlqenvttiamvtklkegdkikcgkyWPdkpgdsvkfGsi
EVHLVSEHIwCDDYLVRSfyLKNLRTSETRTVTQFHFLSWPHMGVPAQAKALLDFRRKVnKSYRGRRSCPIVVHGSAGAGRTGVYILLDLVLERMNKgAR
.|.||| . | . . | |. |. ...|||||||| ||. ||| ....|| . ..| |. .|. . |...| |||.|||||.| .| |. .... .|
kvelvslea.ctggikrk..ltvlkgddsrtvtqfhfteWPdkGvpkhtssllklikev.kadhgqythpliihcsaGvGrtGvvisidsvvahakt.tr
EIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAEEVH
.|. ... .|..| .| |..|. |. || |...
mvdvfnfvtnirqkrpylvqtqeqyafiygavledll
|
|||||||||
subfamily_PTPN5_RR_pd | Subfamily PTPN5_RR | 989-1223 | 5e-53 | 174.9 | In-house | 32-269 (274) | alignment | ||
Range on Protein: 989-1223
Range on HMM: 32-269/274.0
NRPGAPLPYDHSRVVLN-HLANAEGLDYVNASTITDHDPRAPAYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCRLQENGEVACARYWPEEG-AEV---Y
|| . || ..|||.|. . ...| ..|.|| | | . ||||.|||||.|.| ||.||... . ||| | .|.|. | ||.|.|.. .|. |
nryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntvadfWrmiyqeevqvivmltklkeaneqkCavyfPdaedyeisery
HIYEVHlVSEHIWCDDYLVRSFYLKNLRTseTRTVTQFHFLSWPHMGVPAQAKALLDFRRKVNKSYRGR--RSCPIVVHGSAGAGRTGVYILLDLVLERM
|.. |.. . ..|| ||...||.| .|.|. . . .|| . .| .|..|||. ..|..| . . . |.||| ||| ||||..| .. . ..
gdveik.vekiverndysvrklvlkyler..ersvkhywytdWPdhksPddantlldlvleveesreeenaklapvvvhCsaGiGrtGcfiaisiavrql
NKGaREIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAEEVH
.. .|. . .|| .| |.| |..|.|.. |... ..
ree.ivvdvlkivcnlrldrGGmvqtseqyelihralclylk
|
|||||||||
subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 989-1218 | 3.4e-51 | 168.8 | In-house | 7-235 (237) | alignment | ||
Range on Protein: 989-1218
Range on HMM: 7-235/237.0
NRPGAPLPYDHSRVVLNHlaNAEGLDYVNASTITDHDPRAPAYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCRLQENGEVACARYWPEE-GAEVYHIYE
|| | ||||||||. . | ||.||. . . | |.|||||| |. ||||.|.. ||| | | |. |. | .|||. . | ..
nrygnivaydhsrvvlkg..agsgsdyinatylkgfdgtpkkyiaaqgplesscddfwqmvwqekcsvivmltgliegnelkchkywpstdqpaaygvlt
VHLVSEHIWCdDYLVRSFYLK-NLRTSETRTVTQFHFLSWPHMGVPAQAKALLDFRRKV-NKSYRGRRSCPIVVHGSAGAGRTGVYILLDLVLeRMNKGA
| | . .. || |||. | .|. | | . |..| |||. ||| |. ||| ||... |.| .|.| ..| ||| ||||.....| .| | |
vslkkkeefs.dytvrslllskrltlkevrlihqyqftswpdrgvpqqtaallrfrkniinrsphvsesgpwiihcsagvgrtgiflvidaml.rqakek
REIDIAATLEHLRDQRAGVVATRQQFEFVLMAV
. .|| . . ..| .. |..|. |. ..
kvvdiynyvysieedrpyiiqtkdqyvfihqti
|
|||||||||
subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 989-1224 | 6.5e-49 | 161.6 | In-house | 55-286 (297) | alignment | ||
Range on Protein: 989-1224
Range on HMM: 55-286/297.0
NRPGAPLPYDHSRVVLNHLANAEGLDYVNASTITDHDPrapAYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCRLQENGEvACARYWPEEGAEVYHIYEV
.| |||| ||| |. . . |||||| . ... | | ..|.| ||.|.... . .|| | ..|. . |||||...| . |
sRYkniLPydssRvkLaivnddpdsDyvnasfvkgnkh...rlittqmPmkatvadfWamvldeqvstivmlnddnerdk.kcaryWsdkgvttfGdvsv
HLVSEHiWCDDYLVRSFYLKNLRTSETRTVTQFHFLSWPHMGVPA--QAKALLDFRRKVNKSYRGRRSCPIVVHGSAGAGRTGVYILLDLVLERMNKgAR
| | . . .. |.. ... .. .| | |..|..||. |. .|..||.. |.|.. .. ..|..|| .|| |||||.. .| |. ....
vllsvs.ereGfikrelevtkgkakarrvvkqyqfveWPdkaverkdsassllklisevrkdfsqnaegPllvhclaGvGrtgvlltidsvvaeakr.ek
EIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAEEVHA
|.|| ....||..| .| |..|..|| || | . .
evdifglvkklrqerpylvqtkeqykfvyvavlealls
|
|||||||||
subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 989-1220 | 8.7e-49 | 161.1 | In-house | 53-277 (315) | alignment | ||
Range on Protein: 989-1220
Range on HMM: 53-277/315.0
NRPGAPLPYDHSRVVLNHLANAEGLDYVNASTITDHDpRAPAYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCRLQENGEVACARYWPEEgAEVYHIYEV
|| ..||.||| | | | .. |||||. | .. . |.|||||..... ||....|. || | | |. . . .|||.. .| . |
nryiniiaydksrvqlpllendphsdyvnanfidGyn.kkrryiaaqgpnvasvkdfwrlvfeedigkivmltnlvegekrkaekywpdk.kviyGkitv
HLVSEHIWcDDYLVRSFylKNLRTSETRTVTQFHFLSWPHMGVPAQAKALLDFRRKVNKsYRGRRSCPIVVHGSAGAGRTGVYILLDLVLERMNKgAREI
..|| . ..| ||.. .. |.| |.|. ||| ||||. . .|... |.|.. .. ..|||| ||| |||| .| || ||.... . |
trkseevn.teytvrtl..svvfgdnirevvqlhytswpdmgvpkytiplmnlirtvkq.hhtnsvgaivvhcsaGvGrtGtfitldavldqaea.enai
DIAATLEHLRDQRAGVVATRQQFEFVLMAVAE
|. .. .|..| ..|.. .|..|. |. |
dvynfitgvrqnrikmvqvaeqyqfiydalle
|
|||||||||
subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 989-1220 | 2e-48 | 159.6 | In-house | 12-239 (239) | alignment | ||
Range on Protein: 989-1220
Range on HMM: 12-239/239.0
NRPGAPLPYDHSRVVLNHLANAEGLDYVNASTITDHDPRAPAYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCRLQENGEVACARYWPEEGAEvYHIYEV
|| . ||||||||..|.| ||.||| . |.| ||.|.|| . . ||.|.|.. .||| | | | . | .|||. .. | |
nryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpdstsk.ycnlrv
HLVSEHIWCdDYLVRSFYLKNLRTSETRTVTQFHFLSWPHMGVPAQAKALLDFRRKVNKS-YRGRRscPIVVHGSAGAGRTGVYILLDLVLeRMNKGARE
| ... ||..|.| . .. .| | | |.|| || ||| | |.| .|||. | | | | |.| ||| |||| ....| .| | | .
tlrktevfa.dyiirtfvmsqvgqteeryvyqyhftvwpdkgvpqyatavlglrrkitkdslpgar..pwvihcsagvgrtgaflvidaml.rqakkqkt
IDIAATLEHLRDQRAGVVATRQQFEFVLMAVAE
.|| .. .|..| .| | .|. |. .|| |
vdifnyvkairedrphmvqtseqyvfihlavle
|
|||||||||
subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 992-1084 | 6.9e-09 | 29.5 | In-house | 55-162 (349) | alignment | ||
Range on Protein: 992-1084
Range on HMM: 55-162/349.0
GAPLPYDHSRVVLNHLANA--------------EGLDYVNASTI--TDHDPRApAYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCRLQENGEVACARYW
|||.||||.|.. .. ||.|| . | .. |.| | |||||. |...| .| ....| .|.. | .||
kdilPyehsrvklkkslksskvikastsesdsgklddyinanylkltrisvek.kyiatqaPlPstvddfykvillngvklvlsLnddkelslekcdiyw
PEEGAEVYH
| . ..
qelsysnit
|
|||||||||
subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 993-1220 | 2e-48 | 159.6 | In-house | 15-238 (239) | alignment | ||
Range on Protein: 993-1220
Range on HMM: 15-238/239.0
APLPYDHSRVVLNHLANAEGLDYVNASTITDHDPRAPAYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCRLQENGEVACARYWPEEGAEvYHIYEVHLVS
. ||||||||..|.| ||.||| . |.| ||.|.|| . . ||.|.|.. .||| | | | . | .|||. .. | | |
nivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpdstsk.ycnlrvtlrk
EHIWCdDYLVRSFYLKNLRTSETRTVTQFHFLSWPHMGVPAQAKALLDFRRKVNKS-YRGRRscPIVVHGSAGAGRTGVYILLDLVLeRMNKGAREIDIA
... ||..|.| . .. .| | | |.|| || ||| | |.| .|||. | | | | |.| ||| |||| ....| .| | | . .||
tevfa.dyiirtfvmsqvgqteeryvyqyhftvwpdkgvpqyatavlglrrkitkdslpgar..pwvihcsagvgrtgaflvidaml.rqakkqktvdif
ATLEHLRDQRAGVVATRQQFEFVLMAVAE
.. .|..| .| | .|. |. .|| |
nyvkairedrphmvqtseqyvfihlavle
|
|||||||||
subfamily_Sponge-PTP6_pd | Subfamily Sponge-PTP6 | 995-1222 | 9.7e-42 | 137.9 | In-house | 58-279 (439) | alignment | ||
Range on Protein: 995-1222
Range on HMM: 58-279/439.0
LPYDHSRVVLNHLANAEGLDYVNASTITD-HDPRapAYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCRLQENGEvacarYWPEEGAEVYHIYEVhLVSE
..||.||.|. . |.|| | .|.. |.|.||| | .||....|. .| || |. | | ||| .. .| | |
gafdhtrvtlqeipgvphshyinanyikGyyddk..lyiatqgpkkettddfwrlviekktvtivmltnlvesyk.....ywpsdaevcygdiav.rvdr
HIWCDDYLVRSFYLKNLR--TSETRTVTQFHFLSWPHMGVPAQAKALLDFRRKVNKSYRGRRSCPIVVHGSAGAGRTGVYILLDLVLERMNKgAREIDIA
| .| .| | . | | | ||| |||...||. ||||| .||| | .| . . |.||| ||| |||| | ||. ||... ..||
nielpnyvirgfkvfnerdttekertvlqfhyiawpdknvpaqashvldflrainsandkeeygpvvvhcsagvGrtGtiialdialeqlkl.enkvdik
ATLEHLRDQRAGVVATRQQFEFVLMAVAEEV
.. ||.|| .| . |. |. || |..
givkvlrkqrkqmvqalcqyvfiynavledi
|
|||||||||
subfamily_eak_pd | Subfamily eak | 995-1142 | 9.6e-10 | 32.4 | In-house | 61-204 (332) | alignment | ||
Range on Protein: 995-1142
Range on HMM: 61-204/332.0
LPYDHSRVVLNHlANAEGLDYVNASTItDHDPRAPAYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCRLQENGEVACARYWPEEGAEV--YHIYEVHLvS
.|||. | | . . | |.||| . . |. . . . . ||||. || . || | |.. .|.|... |. . |..|.
vpydrylvrlts.sqlnrlGyinasla.efsevGrkyiltGiasedkvfafwqmvleqkspaivqlledvelkleksdkyfpdktreelkfGildver.k
EHIWCDDYLVRSFYLKnlRTSETRTVTQFHFLSWPHMGVPAQaKALLDFR
|.. . . .| . |. . || | ... | . .| . .| .|
efvkrniletrllels..kGnethrvlhykvfGwtettlpky.edflalr
|
|||||||||
subfamily_Sponge-PTP-4_pd | Subfamily Sponge-PTP-4 | 995-1091 | 9.3e-06 | 20.0 | In-house | 3-83 (130) | alignment | ||
Range on Protein: 995-1091
Range on HMM: 3-83/130.0
LPYDHSRVVlnhlanaeGLDYVNASTITDHDpRAPAYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCRLQENGEvacarYWPEegAEVYHIYEVHLV
|... ||. | .|.||| . . |. |. .| || | .||.|. |. |.| | ..|. | |||. .| .. || ...
lefevsrlq........gntyinasfvGllg.rtaeylltqhpladtsmdfwkmmleryvnvlvvlgsveeede.....ywpd..sePlewyeedii
|
|||||||||
0044763 | (Phosphotyrosine protein) phosphatases II | 996-1216 | 9.1e-28 | 92.5 | In-house | 1-165 (178) | alignment | ||
Range on Protein: 996-1216
Range on HMM: 1-165/178.0
PYDHSRVVLNHLANAEGLDYVNASTITDHdprapAYVAAQGPlpstlAHFWQMIWEQGAVVIVALCRLQENGEVACARYWPEEGAevyhiyevhlvsehi
|.|..||.|..| . |. || ||| |... |.....| |.......|.| .|| |. .|.| . | .|||||
pldrtrvllsnleglersdyinaseilpg.....lylgslpp.....addlellkelgithivnlteelelgflkcdpywpeeag...............
wcddylvrsfylknlrtsetrtvTQFHFLSWPHMGVPAQAKALLDFRRKVNKSYRgRRSCPIVVHGSAGAGRTGVYILLDLVLERmnkgarEIDIAATLE
|.... .| .||| . .|.| . ... . .. .|..|| ||| ||.|. ....|.... ... . .|
.......................iqylhipipDhgvpdllehflefvefieeald.ekggpvlVHCsaGvgRsgtlvaaylmkkl......glsleeaie
HLRDQRAgVVATRQQFEFVLM
..| .| .| .. | .....
lvrerRp.ivpnpgqlrqLye
|
|||||||||
subfamily_Cele-PTP-13_pd | Subfamily Cele-PTP-13 | 997-1215 | 4.3e-27 | 89.5 | In-house | 49-262 (281) | alignment | ||
Range on Protein: 997-1215
Range on HMM: 49-262/281.0
YDHSRVVLNH-LANAEGLDYVNASTITDHDpRAPAYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCRLQENGEVACARYWPEEGAEVYHIYEVHLVSEHI
| ||| |. . | . ||. | | |. .||| | | ||.|||.. . || ||.. | || |.| . . .. .. . |
ldisrvqlkvkmpnknstdyihanyirspf.lkrgyiltqgpkketradfwrmiwqenttaivmlcqfletnrekcaeyfprnahcclqfdklsvsyeds
WCDDYLVRSfYLKNLRTSETRTVTQFHFLSWPHMGVPAQAKALLDFRRKVNKsyrgrRSCPIVVHGSAGAGRTGVYILLDLVLERMNKGAREIDIAATLE
. || . |. ||| .|.. . || || .. .| ||. || | |.| ||| ||.| . ... |. . || .
tvnkslvtt.rlnlsyegetrlithwlwkewpdwqvpessevmlkilrkira.....rstppvihcsagvgrsgtlmaveialqsihshftlpdikqivs
HLRD-QRAGVVATRQQFEFVL
||| || | | ||. ..
hlrvtgraasvqtlqqymliw
|
|||||||||
subfamily_Cele-PTP-6_pd | Subfamily Cele-PTP-6 | 997-1214 | 7.7e-26 | 85.8 | In-house | 53-269 (307) | alignment | ||
Range on Protein: 997-1214
Range on HMM: 53-269/307.0
YDHSRVVLNHLANAegLDYVNASTITD-HDPRapAYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCRLQENGEVACARYWPEE-GAEVYHIY------EV
|..|.|.. | ||. | . .|. ...||||| .| .|| |. .. .. ||.. | ... | .||| | | . .
qdkgrivvkfdgla..sdyihanylgiaikpk..kficaqgplentqysfwamaiqekvesvimlckvielakikceqywpleegqklvfgeapntisva
HLVSEHIWCDDYLVRSFYLKNLRTSETRTVTQFHFLSWPHMGVPAQAKALLDFRRKVNKSyrgrrSCPIVVHGSAGAGRTGVYILLDLVLERMNKGAREI
| .... |. |. || ....||.... . || ||| . ... |. |.||| ||| ||.| . . || ..| .|
nlgakklapdedlinvttlkvdwaqksrtiqhlqwenwpdrgvpqinltainlleavryd.....tnpvvvhcsaGvGrsGtivaislvqdkmiaGinck
DIAATLEHLRDQRAGVVATRQQFEFV
|. .| ||.|| . | |. ..
dmkklveelrsqrhyaiqteaqylyl
|
|||||||||
subfamily_Cele-PTP-14_pd | Subfamily Cele-PTP-14 | 997-1214 | 2.4e-19 | 64.1 | In-house | 64-282 (310) | alignment | ||
Range on Protein: 997-1214
Range on HMM: 64-282/310.0
YDHSRVVLNhLANAEGLDYVNASTITDHDPRApAYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCRLQENGEVACARYWPEEG-AEVYHIYEVHLVSEHI
| ||| |. . .. ||. | . |. ... .|||| |. ||.||... | |. ||. |.| | ||| | .| | | .||
ldtsrvklk.idksryedyihanyvktnylrs.tficsqgplqhtiidfwrmifqeraesilllckvgeegrpkcvgywpslgvtetygcirvtnlsess
--WCDDYLVRSFYLKNLRTSETR------TVTQFHFLSWPHMGVPAQAKALLDfRRKVNKSyrgrRSCPIVVHGSAGAGRTGVYILLDLVLERMNKGArE
. | .| |. | |. .. || .||| . . .| . . | | ||| ||| .|..| . |.| ......| .
eefeicnlavtfvpdnvpvdeqpanlkelrvslikwpnwpdrgvpdekchtvp.qrllaqv....rhgpcvvhcsagkdrlyvvvalklkidkldrgl.k
IDIAATLEHLRDQRAGVVATRQQFEFV
.|. .|. .|| .. | |. ..
vdaeevktellksraiciqtelqylii
|
|||||||||
subfamily_Cele-PTP-16_pd | Subfamily Cele-PTP-16 | 997-1224 | 9.4e-13 | 42.4 | In-house | 59-281 (303) | alignment | ||
Range on Protein: 997-1224
Range on HMM: 59-281/303.0
YDHSRVVLNHlanAeglDYVNASTItDHDPRAPAyVAAQGPLPSTLAHFWQMIWEQGAVVIVALCRLQENGEVACARYWPEEGAevYHIYEVHLVSEHIW
|||.| | . |. || . . | . | . .| ||. | | ||||| || ... | | .. .|.. . .| . .
ldhskvklsd...s...syihasyl.eldsskka.iltqlplshtaadfwqmiieqkvkcvlllltdseydklggdsvfprnqd..flkfeersirvgef
CDDYLVRSFYLKNLRTSETRTV---TQFHFLSWPHMGVPAQ-AKALLDFRRKVNKSYRG-RRSCPIVVHGSAGAGRTGVYILLDLVLERMNKGAREIDIA
|. . || | |. |. .||| .|.. . .. ... | | | | .| ||.| . |.. . . .|.
krvelgdgwvlkvlsvsngdyksflhvhhykawphnsipsdgspkfvkqiwqlqsvlrkysdstptvymslsgcgragtfalfetahlslhseqasldlv
ATLEHLRDQRAGVVATRQQFEFVLMAVAEEVHA
|| .|. | | || .| .|| |
kclenvrngrlhavqnlsqfsvvytllaehvld
|
|||||||||
subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 998-1214 | 1.9e-27 | 90.7 | In-house | 69-275 (290) | alignment | ||
Range on Protein: 998-1214
Range on HMM: 69-275/290.0
DHSRVVLNHlanAEGLDYVNASTITDHDpraPAYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCRLQENGEVACARYWPEEGAEVYHIYEVHLV-SEHIW
| .||.|. ||| | . . . .. .||.| .| .|.|. .... .|| || | |.| |..|.||. || . |. .. ||.
dktrvilkd...GydGdyvhanyvkGlk...amfiltqGalkdtvidiwrmvlqekvaaivmlceliedGkakceqyypekeGevltfGeitvlcseedd
CDD-YLVRSFYLKNLRTSETRTVTQFHFLSWPHMGVPAQAKALLDFRRKVNKSyrgrrSCPIVVHGSAGAGRTGVYILLDLVLERMNKGaREIDIAATLE
|. . . ... . . .. ||| |. . ||| | . | | |.||| ||| |||| .. .. |. . .| .|.|.. .
kdaniikktlsvrdkdsGkehklkhlkikswpdksvalstlallrtlrilrka.....sGpvvvhcsaGiGrtGtfvaievglqilldG.keldlldlvr
HLRDQRAGVVATRQQFEFV
||. |.. | |. .
alrnsrlnsvqvdiqylal
|
|||||||||
subfamily_Cele-PTP-8_pd | Subfamily Cele-PTP-8 | 998-1222 | 1.8e-23 | 78.0 | In-house | 56-271 (288) | alignment | ||
Range on Protein: 998-1222
Range on HMM: 56-271/288.0
DHSRVVLNhlanaEGLDYVNASTITDHDPRAPAYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCRLQENGEVACARYWPEEGAEVYHIYEVHLVSEHIWC
| .|| |. . |. |. . . . || || .|. .|.|. |.. || ||.| | | . | |.| . | .| . | .
ditrvkls.....ddpdfyiaanvvssakykrrlicaqaPlngtieelWkmllesdveyivmlcellekGkeksaeyfPsklGekarigrlctvvkkkra
-DDYLVRSFYLKNLRTSETRT-VTQFHFLSWPHMGVPAQAKALLDFRRKVnKSYrgrrSCPIVVHGSAGAGRTGVYILLdLVLERMNKGAREIDIAATLE
| ||. |.. .. |.. | . |.| |.. ||| . .. | . . ||. ||||| |||.|||| || |. .. . . | |.
didklvkvsllriskegeekvivkilhlleWdddgvPenylsplrllevl.ksl....qkPivvhssaGvGrtgtlili.lialeslrlddflgirslla
HLRDQRAGVVATRQQFEFVLMAVAEEV
.||..| . | .|. .| | ||.
klreerfkaiqtemqylyvhrcvleel
|
|||||||||
subfamily_Cele-PTP-15_pd | Subfamily Cele-PTP-15 | 998-1220 | 2.6e-23 | 77.4 | In-house | 48-268 (285) | alignment | ||
Range on Protein: 998-1220
Range on HMM: 48-268/285.0
DHSRVVLNhlaNaEGLDYVNASTITDHDPRAPAYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCRLQENGEVACARYWPEEGAEVYH--IYEVHLVSE-H
. .||||. | ||. || . .|...||||| ||. ||.||... .. || | | | || |.||. || . ||. |
eetrvvlk...n.hdrdyihaswmrmpgkdqstyittqgplpetlsdfwhmiyqekiayvlmlctlfeggvekcalyypeklgevvkfgkyeitltecke
IWCDDYLVRSFYLKNL--RTSETRTVTQFHFLSWPHMGVPAQAKALLDFRRKVNKSYrgRRSCPIVVHGSAGAGRTGVYILLDLVLERMNKgAREIDIAA
.. .. . | .|| . . . || | .|. .... . |.| . ||.|| ||| ||| .. .| |. . .|..
eaiagtilnaltvintedasseplymnhvqvpwwpdqlapedarpmielykwvkkvn..pkekpicvhcsagvgrtatfvgidyatirime.npniemld
TLEHLRDQRAGVVATRQQFEFVLMAVAE
. .| | | .. || |. . . |
ivremramrfqavqshmqflflyvvlme
|
|||||||||
subfamily_Cele-PTP-4_pd | Subfamily Cele-PTP-4 | 998-1219 | 2.3e-13 | 44.2 | In-house | 64-282 (302) | alignment | ||
Range on Protein: 998-1219
Range on HMM: 64-282/302.0
DHSRVVLNHLANaeglDYVNASTITDHDPRAPAYVaAQGPLPSTL---AHFWQMIWEQGAVVIVALCRLQENGEvACARYWPEEgAEVYHIYEVHLVSE-
|. .| |.. .. .|||||... . . . .. || | .. ..||.|.... | .| | . .| . . ..|.. .. |. |. |
dsnlvkleaepd....syvnaskvevPeltrsiil.aQlpkvdsedsveeFWrmvfqekivsvvilvgeeelkk.tlselfpkk.sgdykeygkmfvNnr
HIWCDDYLVRSFYLKNLR--TSETRTVTQFHFLSWPHMGVPAQAKALLDFRRKV-NKSYRGRRSCpiVVHGSAGAGRTGVYILLDLVLERMNKGaREIDI
. . . ... | |.. .. .. |.. || . .| || .|. . .. |. |||| |. . | ...|...|| | |
kVekaeeektryviEvlPegcsnsvlanvyvltnWkqkkvpvkyaeliktaakvfakkikadent..vivSknGaGRagafltlavaveklqkg.kepni
AATLEHLRDQRAGVVATRQQFEFVLMAVA
. ... .| ||. .| . .|. .. .|..
keivksiRsqRpravdslkQyvslyiall
|
|||||||||
subfamily_egg_pd | Subfamily egg | 998-1219 | 4.7e-10 | 33.6 | In-house | 53-267 (307) | alignment | ||
Range on Protein: 998-1219
Range on HMM: 53-267/307.0
DHSRVVLNHLANAEGLDYVNASTITDhDPRAPAYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCRLQENgeVACARYWPEEGAEVYHIYEVHLVSEHIWC
| ||| |. |.. | . .| .. || || | ||.|.... || | .|. | ||| .. . | | .
dssrvklelrrGqylddfihanrvkG.kpllnefilaqaplkntvddfwrmvfqeevqyivmltsrkes..erceyywpkaesdslvtvpGslrienlkv
DDYLVRSFYLKNLRTSETRtVTQFHFLSWpHMGVpaQAKALLDFRRKVNKSYRgRRSCPIVVHGSAGAGRTGVYILLDLVLERMNKGA-REIDIAATLEH
|. | . .|. . . . | | . . . . .| . | . | |.||. | .... . ... | . .| . .
dskadplfrvtklklvGgd.deerflehw.qgdv..nnssdvysplrvlrklr.nlskpvvvqdilGvskaatlvaieiallsllrGpitkslvlravvf
LRDQRAGVVATRQQFEFVLMAVA
|| .| | . .. || |.
lrlrrrlsvesvllylfvyrlvl
|
|||||||||
subfamily_Cele-PTP-1_pd | Subfamily Cele-PTP-1 | 999-1219 | 7.8e-16 | 53.0 | In-house | 32-256 (290) | alignment | ||
Range on Protein: 999-1219
Range on HMM: 32-256/290.0
HSRVVLNHLANAEGLDYVNASTITDhdPRAPAYVAAQGPL-------PSTLAHFWQMIWEQGAVVIVALCRLQENGEV----ACARYWPEEGAEVYHIYE
..||||. . ||. |. .| | . .. | |. ||. .|| |. . . .| || .|. . |||.| ||. | .
atrvvLkgygkrfnddyiHAnrvtc..pnglrliltqsPqekitekrnStiekfwwmakqEkvkqvVmlcefeeksantslfaCakYvpesvgeelkfkg
VHLV-SEHIWCDDYLVRSFYLKnLRTSETRTVTQFHFLSWPHMGVPAQAKALLDFRRKVNKSyrgrrSCPIVVHGSAGAGRTGVYILLDLVLERMNKGAR
. . . . || .| .| | ||| . .| .. |. . | ||. .||..| |..|| | | . ..| . .
ltvkCkskekeddvetRelvvk.fddeeeftvtHsllkgWnklnvqedtktllsliqkvkas.....ktpvivHcvdGiSrsAalaaiilgyQkiaetsg
EIDIAATLEHLRDQRAGVVATRQQFEFVLMAVA
.. ... |. || ||| .. . ... ||. ..
svkledvlkalrkqralaitsalelafvdagiv
|
|||||||||
subfamily_Cele-PTP-10_pd | Subfamily Cele-PTP-10 | 1007-1214 | 2.7e-24 | 80.3 | In-house | 74-281 (305) | alignment | ||
Range on Protein: 1007-1214
Range on HMM: 74-281/305.0
LANAEGLDYVNASTITDHDPRAPAYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCRLQENGEVACARYWPEEGAEVYHIYEvHLVSEHIWCDDYLVRSF-
|.. ||. | . ...||||| |. .|| |. .. || ||. | | . ||.||| | .. .| | . . |
ldkpspsdyihanyvgcpmipekrficaqgpldqtidefwwmviqnkveqivmlcktvelgklkcaqywpaaqgeklelks.givvenvsgskpmerdae
---YLKNLRT--SETRTVTQFHFLSWPHMGVPAQAKALLDFRRKVnksyRGRRsCPIVVHGSAGAGRTGVYILLDLVLERMNKGAREIDIAATLEHLRDQ
| || ... .| .... || ||| . |.. . || . ||||| ||| |||| . .. .||.. . . . . ||||
iqitllnltysgdqkmsvrhlqwtewpdrgvppckltslellsai....rgsk.vpivvhcsagigrtgtivaieyilekiaenkpcppmpelvkalrdq
RAGVVATRQQFEFV
|| . . |. |.
rafsiqndvqylfi
|
|||||||||
0043147 | (Phosphotyrosine protein) phosphatases II | 1011-1215 | 8.3e-33 | 108.9 | In-house | 3-154 (172) | alignment | ||
Range on Protein: 1011-1215
Range on HMM: 3-154/172.0
EGLDYVNASTItDHDPRAPAYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCRLqengevacarywpeegaevyhiyevhlvsehiwcddylvrsfylKNL
|| ||.||| . | . ..| ||||..|||.||.|..|.| .|| |..| ..
egsdyinasyl.dlyyipdrfiatqgplrntladfwrmlkelgithivnltel............................................lyd
RTSETRTVTQFHFLSWPHMGVPaQAKALLDFRRKVNKSYRGRRSCPIVVHGSAGAGRTGVYILLDLVLermnkgaREIDIAATLEHLRDQRAGVVATRQQ
.. ..|.. |...|.|| .||| .. ||.| . ... . ....|..|| ||| ||||. ....|.| . ... .....|..| |.| . .|
pellerlgiqylylpwpDhgvp.llellleflefidellalspggpvlVHCsaGvgRtgtlvaaylml.......lglsleeavalvrekRpgavqnpsq
FEFVL
|..
yrfly
|
|||||||||
0046846 | (Phosphotyrosine protein) phosphatases II | 1013-1218 | 2.3e-32 | 107.5 | In-house | 12-169 (176) | alignment | ||
Range on Protein: 1013-1218
Range on HMM: 12-169/176.0
LDYVNASTITDHdprapAYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCRLQENGEVACARYWPEEGAEVYhiyevhlvsehiwcddylvrsfylknlrt
|||.||. | . ...| |||||.|||.|..|..|.| ..| |. ..| | . |..||||. .. .
ldyinanlilgs.....rpiatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpeleklgi.............................
setrtvtQFHFLSWPHMGVPAQaKALLDFRRKVNKSYRGRrsCPIVVHGSAGAGRTGVYILLDLVLERmnkgaREIDIAATLEHLRDQRA-GVVATRQQF
|...| || .||| ..||.. . ... .. |..|| ||| ||||......|. . . ... .|...|.|| |.| |..|
.......qylhlpwpDhgvpdl.elllellefirealkeg..gpvlVHCsaGigRtgtlvaayllele.....kglsveealalvreqRplgavqtpeQy
EFVLMAV
.|. ...
rflyefe
|
|||||||||
0051429 | (Phosphotyrosine protein) phosphatases II | 1014-1224 | 1.1e-37 | 125.6 | In-house | 5-227 (272) | alignment | ||
Range on Protein: 1014-1224
Range on HMM: 5-227/272.0
DYVNASTITDHdPR---APAYVAAQGPLPSTLAHFWQMiWEQGAVVIVALCRLQENGEVACARYWP------------EEGAEVYHIYEVHLVSEHiWCD
.|.||. . | .. ...|||| | |.||.. .|.| .|| |... | | . | |||| .. |. . | |.||. ...
gyiNardvggy.grvvkpgrlyrsggplpltaadfwrl.kelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllsee.lll
DYLVRSFYLKNL-RTSETRTVTQFHFLSWPHMGVPAQAkaLLDFRRKVNKsyrgrrSCPIVVHGSAGAGRTGVYILLDLVLERMNKGAREID-------I
||..| ..|..| ..|.|.|...|...|| .||| .| ||.. . ... . |..|| ||| .|||....|.|.|..... . | .
dyilrellltlllsagearevmhlhytdwpdhgvpqea..llellellld......ggpvlvHCsaGkdRTGtvvallllllgvsletivddYlltnlyl
AATLEHLRDQRAGVVATRQQFEFVLMAVAEEVHA
....|.||.||.|.| | .|..|...|..| . .
eeaveelraqrpgavqteeqylflyeallellrs
|
|||||||||
0036282 | (Phosphotyrosine protein) phosphatases II | 1014-1215 | 1e-32 | 108.6 | In-house | 3-163 (174) | alignment | ||
Range on Protein: 1014-1215
Range on HMM: 3-163/174.0
DYVNASTItDHDPRAPAYVAAQGPLPstlahFWQMIWEQGAVVIVALCRLQENGEVACARYWPEegaevyhiyevhlvsehiwcddylvrsfylknLRTS
|| ||| . | . | ..| ||||. ||.|..|.| ..| |....|.| . | .|||| ||..
dyinaspl.dlsyitprliagqgpla.....fwemlkelgittvvmlleekelglykcinywpe................................lred
ETRTVTQFHFLSWPHMGVPAQAKaLLDFRRKVNKSYRGRRSCPIVVHGSAGAGRTGVYILLDLVLERMNkgAREIDIAATLEHLRDQRAGVVATRQQFEF
..|.. |...| || .||| .. ||.| . |.. . ...|..|| ||| ||||. ....|.| .. . .|. ... || || |.| | .|..|
lerlgiqylylpwpDhgvpdlsi.llefvkfveealsedpggpvlVHCsaGvgRtGtlvaaylmlrgll..eslvdaldlvrelRlqrpgmvqtpsQyrf
VL
.
ly
|
|||||||||
0051082 | (Phosphotyrosine protein) phosphatases II | 1014-1218 | 5.2e-28 | 92.9 | In-house | 4-149 (151) | alignment | ||
Range on Protein: 1014-1218
Range on HMM: 4-149/151.0
DYVNASTITDHdprapaYVAAQGPLPstlaHFWQMIWEQGAVVIVALCRLQENGevACARYWPEEGaevyhiyevhlvsehiwcddylvrsfylknlrts
|| |.| .|.. . . .|||. .|.....|.| .|| |. ..|.| |..|.||.|
dyinfsyvtgg......lyrsggpla....dflellkelgiktivnlrseeerg..ycpeylpelg..................................
etRTVTQFHFLSWPHMGVPAQAKALLDFRRKVNKsyrgRRSCPIVVHGSAGAGRTGVYILLDLVLERmnkgareIDIAATLEHLRDQRAGVVATRQQFEF
..|.....|.|| |.| .|.|.| ..... .. |..|| ||| ||||. ..|.|.|.. ......||..| .| ||| . ||| |
..ievlhipildwpdpglplsfdavleflellld....kkngpvlvHCsaGkgRTGtlvalylmllg.......vsleealeeyrlkrpgvvqpnqqflf
VLMAV
.|.|.
qlfal
|
|||||||||
subfamily_Cele-PTP-11_pd | Subfamily Cele-PTP-11 | 1029-1222 | 5.9e-16 | 53.1 | In-house | 82-276 (312) | alignment | ||
Range on Protein: 1029-1222
Range on HMM: 82-276/312.0
PAYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCRLQENGEVACARYWPE-------EGAEVYHIYEVHLVSEHIWCDDYLVRSFYLKNLRTSETRTVTQF
.|..|||| .| .||||. |.. |. || . |.| ||.| . | || | . | | . . | . . ..
erfvctqgplentcthfwqlalslgstsiillcgfvedgsekcakyisdivgfvdledhrvyteycteieiggkskdkithrvlkvvvkatgqesklnhy
HFLSWPHMGVPAQAKALLDFRRKVNKSYRgrrscPIVVHGSAGAGRTGVYILLDLVLERMNKgAREIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAEE
. ||| |.| . | . |.| . |.. | ||| |||| .|.. .. . . | .. .. || .|| | . |. ..| .| |
qwaswpdhgmpdscdtalrllsavkkdkk.....pviahcsagvgrtgtlaliesmiaalrh.prkqnvkdsfvllrkdrarsvrvfpqyvyalrcvlef
V
.
l
|
|||||||||
0049260 | (Phosphotyrosine protein) phosphatases II | 1030-1215 | 5.7e-32 | 105.9 | In-house | 10-143 (152) | alignment | ||
Range on Protein: 1030-1215
Range on HMM: 10-143/152.0
AYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCRLQENGEVACARYWpeegaevyhiyevhlvsehiwcddylvrsfylknlrtsetrtvtQFHFLSWPHM
...|.|||.| |||.||.|..|.|. .|| |..|.|.|.. |..|. |...| || .
efiatqgpgpntladfwrmlkelgittivmltellelgklkceqyi............................................qylhlpwpDh
GVPAQAKALLDFRRKVNKSyRGRRSCPIVVHGSAGAGRTGVYILLDLVLermnkgaREIDIAATLEHLRDQRAGVVATRQQFEFVL
||| . ||.. . ..| . ....|..|| ||| ||||......|.| . ... .....| .| |.| . .| .|..
gvpdlsqlllflllfiekl.aldkggpvlVHCsaGvgRtgtlvaaylml.......lgvsleeavalvrekRpgavpnpgqlrfly
|
|||||||||
subfamily_Anemone-PTP-3_pd | Subfamily Anemone-PTP-3 | 1030-1214 | 2.9e-24 | 80.4 | In-house | 6-196 (199) | alignment | ||
Range on Protein: 1030-1214
Range on HMM: 6-196/199.0
AYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCRLQENGEVACARYWPEEGAEVYHIYEVHLVSEHIW-CDDYLVRSFYLKNLRTS--ETRTVTQFHFLSW
|.|.| || |.| ||||.|| |. || . | | |. . ||| . . . . .... | || . .. | | |. || .... | ||
ryiatqhplretmadfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyqftsw
PHMGVPAQAK--ALLDFRRKVNKSYRGRRSCPIVVHGSAGAGRTGVYILLDLVLERMNK-GAREIDIAATLEHLRDQRAGVVATRQQFEFV
| | .. |.| | | . .|..|| | | | |||.. ||. . .. . .|. ||. | |.... |...|.
kekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiisslqhynfi
|
|||||||||
subfamily_Nvec-PTP-3_pd | Subfamily Nvec-PTP-3 | 1030-1214 | 3e-24 | 80.3 | In-house | 5-195 (198) | alignment | ||
Range on Protein: 1030-1214
Range on HMM: 5-195/198.0
AYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCRLQENGEVACARYWPEEGAEVYHIYEVHLVSEHIW-CDDYLVRSFYLKNLRTS--ETRTVTQFHFLSW
|.|.| || ||| ||||.|| |. || . | | |. . ||| . . . . .... | || . .. | | |. || .... | ||
ryiatqhplretladfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyqftsw
PHMGVPAQAK--ALLDFRRKVNKSYRGRRSCPIVVHGSAGAGRTGVYILLDLVLERMNK-GAREIDIAATLEHLRDQRAGVVATRQQFEFV
| | .. |.| | | . .|..|| | | | |||.. ||. . .. . .|. ||. | |.... |...|.
kekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiisslqhynfi
|
|||||||||
subfamily_Cele-PTP-19_pd | Subfamily Cele-PTP-19 | 1030-1214 | 8.4e-24 | 78.8 | In-house | 91-273 (301) | alignment | ||
Range on Protein: 1030-1214
Range on HMM: 91-273/301.0
AYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCRLQENGEVACARYWPEEGAEVYHI--YEVHLVS-EHIWCDDYLVRSFYLKNL-RTSETRTVTQFHFLS
..|.||||..| || |. || |.. |. | |. | | . .| .| ....... |.| .. |.. ... . .||||| . . .
rfiatqgPlkntsedfwamlvqydvekivmlgqkvekleekceeylpvkisekldigrfkikiknkelilnkkiskrtlevedstgkfatrtvthyqyse
WPHMGVPAQAKALLDFRRKVNKSYRgrrscPIVVHGSAGAGRTGVYILLDLvLERMNKGAREIDIAATLEHLRDQRAGVVATRQQFEFV
|.. ||| | |. | || . ||||| ||| ||. .| . | | . ..|... .|.|||..| | |..|. ..
wtdrgvPkshaelfdlmelvkksek.....PivvhcsaGiGrsvafigtey.lareveadptieltealkhlrehrwngvqtnsqlywm
|
|||||||||
subfamily_Cele-PTP-7_pd | Subfamily Cele-PTP-7 | 1037-1222 | 8.7e-17 | 55.5 | In-house | 99-288 (302) | alignment | ||
Range on Protein: 1037-1222
Range on HMM: 99-288/302.0
PLPSTLAHFWQMIWEQGAVVIVALCRLQENGEVACARYWPEEGAEV--YHIYEVHLVSEHIWCDDY------LVRSFYLKNLRTS--ETRTVTQFHFLSW
| ||| .| .| . ..| || . |..| || |. .. .. . | |. || . ... . . .|| .. .|| ..| .|
pkkstlekhwalieqynvaivvqlcsfvedeekkcaeyysdkvggelkfgrytvktvsvktdleeftdkksfklytveiknekkkkkvkktvdilafsaw
PHMGVPAQAKALLDFRrKVNKSYRGRrscpIVVHGSAGAGRTGVYILLDLVLERMNKgAREIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAEEV
|. | |..|.. || | .||. ..|| ||| |||| . . .. | . |.. . .|. | | | . || ..|. |. .
pdhGapkeaytaldil.kfcesykkn....vlvhcsaGvGrtGtlvaikyGiqlcsk.kkvtdllsivlpvrqcryGavqdeqqliylllcvtkgl
|
|||||||||
subfamily_hpo-7_pd | Subfamily hpo-7 | 1039-1220 | 5.1e-19 | 63.2 | In-house | 44-225 (263) | alignment | ||
Range on Protein: 1039-1220
Range on HMM: 44-225/263.0
PSTLAHFWQMIWEQGAVVIVALCRLQENGEVACARYWPEEGAEVYHIYEVHLVSEHIWCdDYLVRSFYLKN-LR-TSETRTVTQFHFLSWPHMGVPAQAK
|.. |.|.| ... |.| || .|.| . | .|.| | | . .| ... .. | |... | . | .|.||... . |.. | .|.
vqtidkfyqtivqtktevvvmLcDfneegvekcssyfPlekdekqklanvnvcttkvqs.dvllktlellstlgeKkkthtvkhysykgWiekndpelar
ALLDFRRKVNKSyRgrrscPIVVHGSAGAGRTGVYILLDLVLERMNK-----GAREIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAE
| . . .| . ..||| |.| ||. . . .|| .| . . |.| ||.|| .|.. . | |. | .. | .
eilnilkvarns.k.....slvvhcstGiGrsaafsvaElvyqkmirsldttstveldylsLleelrssrkraihtPmqLafsilmvLd
|
|||||||||
subfamily_Cele-PTP-9_pd | Subfamily Cele-PTP-9 | 1041-1222 | 5.7e-21 | 69.7 | In-house | 40-221 (255) | alignment | ||
Range on Protein: 1041-1222
Range on HMM: 40-221/255.0
TLAHFWQMIWEQGAVVIVALCRLQENGEVACARYWPEEGAEVYHIYEVHLVSEHiWCDDYLVRSFYL-KNLR-TSETRTVTQFHFLSWPHMGVPAQAKAL
|...|.|.| ... |.| || ..|.| . | .|.| | | . .| ... . | ..| . .| .|.||. ... |. | .|. .
tvdkfyqtivqtktevvvmlcdfaeegvekcssyfplekdeklkladvnvtttk.ssadvvlrtleitstlgekkkthtvkhysykGWieknaPelarei
LDFRRKVNKSyRgrrscPIVVHGSAGAGRTGVYILLDLVLERMNK-----GAREIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAEEV
| . | .| . ..||| |.| ||. ..| .|| .| . . |.| ||.|| .|.. . | |. | .. | . |
lnilkvvrds.k.....svvvhCstGiGrsaafvlaelvyqkmirsldttetveldylslleelrskrkraihtPlqlafsilmvldlv
|
|||||||||
subfamily_PTPDC1_pd | Subfamily PTPDC1 | 1093-1214 | 1.4e-06 | 22.9 | In-house | 58-168 (182) | alignment | ||
Range on Protein: 1093-1214
Range on HMM: 58-168/182.0
EHIWCDDYLVRSFYLKNLRTSETRTVTqFHFLSWPHMGVPAQaKALLDFRRKVNKSYRGRrscPIVVHGSAGAGRTGVYILLDLVLERmnkgarEIDIAA
|| | | .| . .| . .. .. ..|. ||.. . .|| . |. . . . || || ||||| | || . ... .
ehasCGagleesGfsYdlealmeqgiy.vynfgwkDygvasl.eriLdivkvvafalqeg...kvavhChaGlGrtGvliacylvyak......rltaek
TLEHLRDQRAGVVATRQQFEFV
... .|..|. . ||.| |.|
aiklvrskrpksiqtreqvelv
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 1099-1222 | 1.9e-19 | 64.3 | In-house | 76-194 (440) | alignment | ||
Range on Protein: 1099-1222
Range on HMM: 76-194/440.0
DYLVRSFylknLRTSETRTVTQFHFLSWPHMGVPAQAKALLDFRRKVNKSYRGRRSCPIVVHGSAGAGRTGVYILLDLVLeRMNKGAREIDIAATLEHLR
||. |. . |.||. |.|. .|| ||| | .| . . ||.| . |..|| ||||||||| | .| .| | | . .||| . .. .|
dyinasy....ingiesrtlkqyhyqgwpdkgvpkfagpvlkmiqdvnesqekagngpllvhcsagagrtgviiavdsil.reakrsdqidifsfinsmr
DQRAGVVATRQQFEFVLMAVAEEV
..| .| | .|. || || | .
nnrpqmvqtpeqyafvheavlegl
|
|||||||||
0048179 | (Phosphotyrosine protein) phosphatases II | 1100-1216 | 5.9e-18 | 60.4 | In-house | 31-139 (144) | alignment | ||
Range on Protein: 1100-1216
Range on HMM: 31-139/144.0
YLVRSFYLKNLRTSETRTVTQFHFLSWPHMGVPAQAKALLDFRRKVNKSYRgrRSCPIVVHGSAGAGRTGVYILLDLVLermnkgAREIDIAATLEHLRD
..| .. . ....|...|...|.|| .||| .. ||.| . ... .. ...|..|| ||| ||||......|.. . ... .|...|
ttvinlteeyepefleregiqylhlpwpDhgvpdllellleflefieeale..eggpvlVHCsaGvgRtgtlvaaylmk......klglsleealalvrs
QRAGVVATRQQFEFVLM
.| |.| ...|..|.|.
rrpgavpnpgqlrfLle
|
|||||||||
0048076 | (Phosphotyrosine protein) phosphatases II | 1105-1218 | 6.5e-19 | 63.5 | In-house | 34-139 (145) | alignment | ||
Range on Protein: 1105-1218
Range on HMM: 34-139/145.0
FYLKNLRTSETRTVTQFHFLSWPHMGVPAQAKALLDFRRKVNKSYRGRrsCPIVVHGSAGAGRTGVYILLDLVLErmnkgaREIDIAATLEHLRDQRAGV
. | . .. ..|...|...|.|| .||| .. ||.| . ... .. .|..|| ||| ||||......|.|. . ... .||..| || |.
lnltselellerlgiqylylpwpDhgvpdllellleflefieealkeg..gpvlVHCsaGvgRtgtlvaaylmll......lgvsleealelvrsqrpga
VATRQQFEFVLMAV
| . .|..|.....
vpnpgqlrflyefe
|
|||||||||
PTPc_DSPc_SM00012 | 1117-1220 | 9.6e-28 | 91.8 | In-house | 1-105 (105) | alignment | |||
Range on Protein: 1117-1220
Range on HMM: 1-105/105.0
TVTQFHFLSWPHMGVPAQAKALLDFRRKVNKSYRGRR-SCPIVVHGSAGAGRTGVYILLDLVLERMNKGAREIDIAATLEHLRDQRAGVVATRQQFEFVL
||...|...||..||| .....|.. |.|.|... . | |.||| |||.||||....||..|....|. .|.|| ....||.||.|.| | .|. |..
tvkhyhytgwpdhgvPeesdsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgmvqteeqylfly
MAVAE
.|..|
ralle
|
|||||||||
subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 1143-1217 | 4.7e-09 | 30.4 | In-house | 251-339 (350) | alignment | ||
Range on Protein: 1143-1217
Range on HMM: 251-339/350.0
RKVNKSYRGRRSCPIVVHGSAGAGRTGVYILLDLVLE------RMNKGAREIDIA--------ATLEHLRDQRAGVVATRQQFEFVLMA
.. . || ||.|| ||| ||||... || .|. ..| |..| | .. .|| || .| . .|| |. |
lfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaaktrDlisiivnelrkqrismvqnldqfifiYea
|
|||||||||
subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 1147-1191 | 3e-06 | 20.8 | In-house | 258-305 (349) | alignment | ||
Range on Protein: 1147-1191
Range on HMM: 258-305/349.0
KSYRGRRSCPIVVHGSAGAGRTGVYILLDLVLE---RMNKGAREIDIA
. . .. ...|| ||| |||||.. |||.|. ... |..
lyldtdqlstllvhcsaGcGrtGvlvtldlllsileplqnesnkiklq
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 1152-1218 | 2.7e-12 | 41.0 | In-house | 245-311 (319) | alignment | ||
Range on Protein: 1152-1218
Range on HMM: 245-311/319.0
RRSCPIVVHGSAGAGRTGVYILLDLVLERMNKGAREIDIAATLEHLRDQRAGVVATRQQFEFVLMAV
. |.||| | |.||||. | |. ...... | .|| .. ..| .|| | |..|.||. .
esqGPlvvhcsdGvGrtGlviasdiairsleeskrsvdiPqlvssvrrdrasavltkeqyefiykvl
|
|||||||||
Phage_Nu1 | Phage DNA packaging protein Nu1 | 1192-1235 | 8.5e-07 | 15.0 | Pfam-A | 94-138 (164) | alignment | ||
Range on Protein: 1192-1235
Range on HMM: 94-138/164.0
ATLEHLRD-QRAGVVATRQQFEFVLMAVAEEVHAILKALPANTSG
|. . |. .. |. ....||| ||.|. .||. .| ..
adaqeLknakekkevvetelvtfvLsRvaaeiasiLdgiPlsvqr
|