Gene CG17840 in Drosophila melanogaster

Synonym: Dmel\CG17840, Dmel_CG17840, CG17840

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family Sac
Subfamily FIG4
Protein sequence
ID Type Fasta BLAST phosphatome Note
DmelP052_AA protein Get Run
DmelP052_AA_240-559 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
Sac_COG5329 19-586 1.2e-96 316.0 In-house 2-541 (1070) alignment 
Range on Protein: 19-586
Range on HMM: 2-541/1070.0
KVVLYETRARLYLVGSNNRETRFRLLtidRLAHNRLSIEENANEFNSLEIRRFVASLSGSpkvTSAYGVLGFVRFLEGYYLLLVTKRKCC-AHIGRHLVY
|..|.|.  | . ..||.... || |       ..||. ..   . | ..    .|||.       |||||.. . . ..| ..|. .   . |... .|
killsekktRsiaivsnkyalvfrrl...svknselsvcaaelvavselkkegfrslssa...heiygvlGlielegslflivitgkskvaqvipgetiy

TIKDTVMVRVNEVTSQRPPH-PHEDRYKR--------MFQNIDLRSNFYFSYSYDLTRTLQYNeSaprYVGAKVDLDRDEPLPDWNtltsnvdkahervd
 | .  .. .|.   .     . | ...          ..  .  . ||||. .|.| ||| . .   . . .   |...  . ||              
kilavdfislnnnkwddeeiesdeasteklrsehpcselkkLlsngsFYfStdfditntLqkr.l...keelelsvdtadeefmwn..............

yafrSDSRKRFVWNAYLLQPMEGIMLKD--WLLEVTHGFVSQSCISIFGRHVNVCLVARRSSRFAGTRFLKRGANFQGDVANEVETEQIVSDGQRICAFT
    |.. . .....  |.. |  .| .  .|  | .||...  |.. .. .   |..||||..||||||.|| .  | |||.||||||| . |.. .||
....sflleelinyrsklsslekqlldnagFlttvIrGFaetvfikvkkktiaLtlISRrSskragtRflarGvDddGnvanFVETEqIvyssqycfsFt

QMRGSIPSHWSQDiSKMVPKPQIQLDICDP-YAQTPSLHFERLLFHYGApLIMLNLVKKRErrkHESIISKELEYSIRyLNQFLPPphrmKHIHFDMARQ
|.|||||  |.|. |.   .|.||    ..   ..   ||..|   ||  .  .||.|. .   .|  .|...|  .. |.....     . ..||. ..
QvRGSiPiFWeqe.snsligpkiqitrsseatqsafdkHFdklfekYGd.vhivNLlktKs...sEieLseryekhlk.lsekpki....hlteFdfhke

SRLSGGNVMEQLAIHAESIVQMTGMFF--KAAGSEPGLQTGIVRTNCVDCLDRTNSAQFAIGKCALGHQLERLGFVKSAKLEfdsDCVTMLENLYEEHGD
..  | .... |  ..|. .   | |.     |     |.|..|||| ||||||| .|. |.| .|. |.. .. ... . |   | .. |..|. ..||
tsqdgfddvkkLlplieqdllefgyfsydvkegkliseQdGVfRtNClDCLDRTNviQqliskrvlleqfrsikvisaidde...dflqklneLWadnGD

TLALQYGGSQLVHRIKTYRKTAPWGSQGSDVMQTLSRYYSNTFSDTEKQHSINLFLGIYKPSltKQGPPIWELQTDYDMHNAF
... .|.|.. . .  |....  . .. ||...  ||.|.| | | ||| .|.|.|| ...   .. . ... ... ......
aisqiYTGtgalkssftrkgkrsiagalsDatkSvsRmyinnfvDkekQdaidllLgklpdq..eavelydpineyvnlrlrk
subfamily_FIG4_pd Subfamily FIG4 20-587 6.4e-264 867.6 In-house 1-564 (569) alignment 
Range on Protein: 20-587
Range on HMM: 1-564/569.0
VVLYETRARLYLVGSNNRETRFRLLTIDRLAHNRLSIEENANEFNSLEIRRFVASLS-----GSPKVTSAYGVLGFVRFLEGYYLLLVTKRKCCAHIGRH
.|||||.|||||||||.|||.||.|.|||.....|...|...||.. ||....|||.     |  |..||||.||||||||||||.||||||..|.||.|
lvlyetkarlylvGsnkretkfrvlkidrtverelvvledkveftkneikellasleeanrdglekkvsayGilGfvrflegyylilvtkrkkvaviGgh

LVYTIKDTVMVRVNEVTSQRPPHPHEDRYKRMFQNIDLRSNFYFSYSYDLTRTLQYNESapryvgakvdldrdepLPDWNTLTSNVDKAHERVDYAFRSD
 .|.|.|. .....| ..... ...|.||...|...||..|||||||||||||||.| .                |.|.|. .............|...|
aiykiedialikitedskksekssdearylklfkdvdltknfyfsysydltrtlqtnll................lsdsnrekekaedrvditieakkld

SRKRFVWNAYLLQPMEGIMLK-DWLLEVTHGFVSQSCISIFGRHVNVCLVARRSSRFAGTRFLKRGANFQGDVANEVETEQIV-------SDGQRICAFT
....||||..||.|.. .. . |||||..|||||||.||..|....|.|.|||||.|||.||||||.| .|||||||||||||       .| .|...|.
anekfvWnnflleplkdtvktfdWlleiihGfvsqskisvlgksiyvtliarrsskfaGarflkrGvnnkGdvaneveteqivheasegsldsdryssfv

QMRGSIPSHWSQDISKMVPKPQIQLDICDPYAQTPSLHFERLLFHYGAPLIMLNLVKKRERRKHESIISKELEYSIRYLNQFLPPPHRMKHIHFDMARQS
|.|||.| .||||.||.|.||.|..|..||.|....|||..|. .||.|.|.||||||.|.||.|||...|.|..|.|||.|||. ...|.|..||||.|
qlrGsvPlyWsqdasklvtkPpikidvvdPfasaaalhfddlfqryGspiiilnlvkkkekrkresilleefeaaieylneflPeekklkyiswdmaras

RLSGGNVMEQLAIHAESIVQMTGMFFKAAGSEPG-LQTGIVRTNCVDCLDRTNSAQFAIGKCALGHQLERLGFVKSAKLEFDSDCVTMLENLYEEHGDTL
. .. ||.|.|. .||..|..||.|..|. .|.  .|.|||||||||||||||.|||.|||.|||.||..||.....|||||||.|..||.|||..||||
kskeenvlevlekyaeksvkktGiflsapdlestkiqeGivrtnCvdcldrtnaaqfvigkvalgyqlkslGiidesklefdsdvvrlleelyedlGdtl

ALQYGGSQLVHRIKTYRKTAPWGSQGSDVMQTLSRYYSNTFSDTEKQHSINLFLGIYKPslTKQGPPIWELQTDYDMHNAFV
||||||||||..||||||.|.| |. .|...||.|||||.|.|..||..||||||.|.|  ... |..|||.||...|||..
alqygGsqlvntiktyrkiaqwssksrdiletlkryysnsfvdadkqdainlflGvysp..reglpslWeletdfylhnays
subfamily_Synaptojanin_pd Subfamily Synaptojanin 80-571 3.4e-59 192.0 In-house 2-446 (754) alignment 
Range on Protein: 80-571
Range on HMM: 2-446/754.0
KVTSAYGVLGFVRFLEG----YYLLLVTKRKCCAHIGRHLVYTIKDTVMVRVNEVTSQRpphpheDRYKRMfQNIDLRSNFYFSYSYDLTRtlqynesap
|.. |||.|| .|   |     .|.|||  |   .|    .. | .| .| ... .|.       ||.  . ...    .|||| | | ..         
kivdaygllGvlrlnagdetlsflvlvtgcksvGkisdaeifkitstelvslrseasde......driiel.kkllasgtfyfsssadsas.........

ryvgakvdldrdeplpdwntlTSNVDK-AHERVDyAFRSdsRKRFVWNAYLLQPME--GIMLKDWLLEVTHGFVSQSCISIFGRHVNVCLVARRSSRFAG
                     . .. . |..| .    .   .||.||  |   ..  |.  .||||.|  | |.   . .  . ....|..| |.  ||
.....................rldlslsaqrrkq.eese..dnrffWnrslhlhlqrfgvncddWllkvmcGsveirtvyagakqakaalisrlsceraG

TRFLKRGANFQGDVANEVETEQIVSDGQRICAFTQMRGSIPSHWSQDISKmVPKPQIQLD-ICDPYAQTPSLHFERLLFHYGAPLImLNLVkkrERRKHE
|||  ||.| .| ||| |||||... ......| |.|||.|  |.|   . | . ...|    .  | . . |.| |  .||  .| .||.    ... |
trfnvrGvndeGnvanfveteqvillddkvtsfvqirGsvPlfWeqPGlq.vGshkvklsrgfeasaaafdrhleqlkeryGevvi.vnll...Gskege

SIISKELEYSIRyLNQFlppPHRMKHIHFDMARQSRLSGGNVMEQLAIHAESI-VQMTGMFFKAAGSEPGLQTGIVRTNCVDCLDRTNSAQFAIGKCALG
...||. .   .  ...    . .....||. .. . .  ...|.|. .. .  .. ...|..  ..    |||..|.||.|||||||. | ..|   | 
evlskafkkhlk.aseh...akdvpfvkfdyhqkvkggkkeklekllkkqlklflesasfflskgkevekeqtGvlrvnClDCldrtnavqtvlglevle

HQLERLGfvKSAKLEFDSDCVTMLENLYEEHGDTLALQYGGSQLVHrikTYRKTapwgSQGSDVMQTLSRYYSNTFSDTEKQHSINLFL--GIYKPSLTK
.||| |.   | | .  |    ....|... || ..  | |.. ..   .  |.    |.  |  ....|   | | |. || .|.|.|    |. .|..
kqlealk..lsskesvvsrfeevfkslWsknGdeiskiyaGtgale...gkakv....sklkdgarsvartiqnnfldsskqeaidllllgntyveelad

QGP
.. 
kar
subfamily_SAC1_pd Subfamily SAC1 81-174 2.1e-17 53.9 In-house 4-100 (458) alignment 
Range on Protein: 81-174
Range on HMM: 4-100/458.0
VTSAYGVLGFVRFLEGYYLLLVTKRKCCAHIGRHLVYTIKDTVMVRVNEVTSQRPP--HPHEDRYKRMFQNIDLRSNFYFSYSYDLTRTLQYNES-A
|.. .|.||... | | ||...||..  ..|  . .|...|. .. |.. . .     . .|..|... ...   ..||||| ||||..|| .|. .
vvkiagilGiikLlsgkylivitkkeevgringkviyrvadveiipvkknslslteeqkkeekeylkllelvlksetfYfsytydltnslqrlekvt
Syja_N SacI homology domain 84-406 6.2e-83 269.5 Pfam-A 1-312 (319) alignment 
Range on Protein: 84-406
Range on HMM: 1-312/319.0
AYGVLGFVRFLEGYYLLLVTKRKCCAHIG-RHLVYTIKDTVMVRVNEVTSQRP--------PHPHEDRYKRMFQNIDLRSNFYFSYSYDLTRTLQYNESA
|||.||..|.|...|||..|||. .|.|. .| .|.||.. ....|. ...           ...|... ....... ...|||||.|||||.|| ....
aygilGlirllsesyllvitkrekvakirgehpiykiksvefiplnseeeessaieeekeeeekeeekllkllkkllssgsfYfSydyDltrslqrksek

PRYVGAKV---DldrdeplpdwntltsnvdkahervdyAFRSDSRKRFVWNAYLLQPMEGIM--LKDWLLEVTHGFVSQSCISIF-GRHVNVCLVARRSS
 .   ..                               .. .. ..||||| .||.|.. .   |..||| . .|||.|. |..  ...|...|..|||.
eeeekeeesksl..........................pllkevderFvWNrnllkplielkldlsrwllpliqGfveqrsievkskkkveltLIsRrsv

RFAGTRFLKRGANFQGDVANEVETEQIVS-D-G--QRICAFTQMRGSIPSHWSQdISKMVPKPQIQLD-ICDPYAQTPSLHFERLLFHYgAPLIMLNLVk
..||||.|.||.. .|.|||.|||||||| .    .|...|.|.|||.| .|.|  |.. .||.|...   ... .. ..||..|. .|  . ...||. 
kraGtRylrRGidddGnvANfvEtEqivsekkeeskrvfSfvqiRGSvPlfWeq.asnlslkpkikitrsseasqkafkkHfkklikrY.gkivvvnLl.

krERRKHESIISKELEYSIRYLNQFLPPPHRMKHIHFDMARQS
  |....|. .|...|  |..||..|.  ...|.|.||. .. 
..ekkgrEkkLseayeelinklnkklkekkklkyiefDfhkec
Syja_N SacI homology domain 84-406 6.2e-83 269.5 In-house 1-312 (319) alignment 
Range on Protein: 84-406
Range on HMM: 1-312/319.0
AYGVLGFVRFLEGYYLLLVTKRKCCAHIG-RHLVYTIKDTVMVRVNEVTSQRP--------PHPHEDRYKRMFQNIDLRSNFYFSYSYDLTRTLQYNESA
|||.||..|.|...|||..|||. .|.|. .| .|.||.. ....|. ...           ...|... ....... ...|||||.|||||.|| ....
aygilGlirllsesyllvitkrekvakirgehpiykiksvefiplnseeeessaieeekeeeekeeekllkllkkllssgsfYfSydyDltrslqrksek

PRYVGAKV---DldrdeplpdwntltsnvdkahervdyAFRSDSRKRFVWNAYLLQPMEGIM--LKDWLLEVTHGFVSQSCISIF-GRHVNVCLVARRSS
 .   ..                               .. .. ..||||| .||.|.. .   |..||| . .|||.|. |..  ...|...|..|||.
eeeekeeesksl..........................pllkevderFvWNrnllkplielkldlsrwllpliqGfveqrsievkskkkveltLIsRrsv

RFAGTRFLKRGANFQGDVANEVETEQIVS-D-G--QRICAFTQMRGSIPSHWSQdISKMVPKPQIQLD-ICDPYAQTPSLHFERLLFHYgAPLIMLNLVk
..||||.|.||.. .|.|||.|||||||| .    .|...|.|.|||.| .|.|  |.. .||.|...   ... .. ..||..|. .|  . ...||. 
kraGtRylrRGidddGnvANfvEtEqivsekkeeskrvfSfvqiRGSvPlfWeq.asnlslkpkikitrsseasqkafkkHfkklikrY.gkivvvnLl.

krERRKHESIISKELEYSIRYLNQFLPPPHRMKHIHFDMARQS
  |....|. .|...|  |..||..|.  ...|.|.||. .. 
..ekkgrEkkLseayeelinklnkklkekkklkyiefDfhkec
subfamily_INPP5F_pd Subfamily INPP5F 196-563 4.2e-70 227.9 In-house 150-507 (951) alignment 
Range on Protein: 196-563
Range on HMM: 150-507/951.0
LTSNVDKAHERVDYAFrsdsRKRFVWNAYLLQPMEGIMLKD---WLLEVTHGFVSQSCISIFGRHVNVCLVARRSSRFAGTRFLKRGANFQGDVANEVET
| ..  . ..     .     .||.||..||.... . .|.   .|. |  |||. . |||   .|.. |. ||| . ||||| .|| . .| |||.|||
lqkrgleeksestddw....derFfWNkfllkdlinyrdkldkefltpviqGfvetkeisieklkvsltlisrrSrkragtrfkrrGidddgnvAnfvEt

EQIVSDGQRICAFTQMRGSIPSHWSQDISKMVPKPQIQLDICDPyAQTPSLHFERLLFHYGApLIMLNLVKKrerRKHESIISKELEYSIRYLNqflppP
|.|.|  . . .|||.|||.|  |.|. .|. ||..|. .  .   ..   ||...| .||  .   ||...   ...|...||  .  .. |.      
ElilsvekyvlsftqirGSvPvfweqsgkkykpkikitrseeet.qpaFdehfkeqlkkygk.vvivnllsq...kssekklskaykeqllkle.....s

HRMKHIHFDMARQSRLSGGNVMEQLAIHAESIVQMTGMFFKAAGS-EPGLQTGIVRTNCVDCLDRTNSAQFAIGKCALGHQLERLGFVKSAKLEFDSDCV
.... |.||. ....  . . ...|    .  ..  |.|..         |.|..||||.||||||| .| ||.| .|  |||.|| ... . . |....
kdvflikfdfheetsgekfenvsklielikneikevgyfsydvkekviseqkgvfRtnclDcldrtNvvqqaiskavlelqleklglfepessiddeell

TMLENLYEEHGDTLALQYGGSQLVHRikTYRKT--APWGSQGSDVMQTLSRYYSNTFSDTEKQHSINLFLGIYK
. |..|. ..||..  || |.. .    .. ..         .| ....|||| | | | ..|. |.| ||  .
qklkklWadngdaisrqYagtnalkg..dltrkgerklaGvlkdgyksvsryylnnfkdkyrqkvidlllGklp
subfamily_SAC1_pd Subfamily SAC1 215-564 7.9e-68 220.1 In-house 113-455 (458) alignment 
Range on Protein: 215-564
Range on HMM: 113-455/458.0
SRKRFVWNAYLLQPM-EGIMLKDWLLEVTHGFVSQSCISIFGRHVNVCLVARRSSRFAGTRFLKRGANFQGDVANEVETEQIVSDGQRICAFTQMRGSIP
  .||.|| .||. . .   |....| |..||.... .|. .....  |..|||   ||||. .||.. .|.||| |||||||.  . . .| |.|||||
adeRffwnkhlledlrkepelesfilPvikGfikikelslnakeikfilisRRsifRaGtRyfvRGvdkeGnvanfvEtEqiveaekaltsFvqvRGsiP

SHWSQdISKMVPKPQIQLDICDPYAQTPSLHFERLLFHYGaPLIMLNLVKKrerRKHESIISKELEYSIRYLNQflpppHRMKHIHFDMARQSRLSGGNV
 .||| ....  ||...|   .   .. . |....  .|| . ...||| .   . .|  . ...|  .| ||.     ...|.. ||  .. |    . 
llWsq.kpnLkykPkvklsesedsldafkkhldeqielyg.envlvnLvdq...kGsEkklgeayesvvralnk.....kkikyvafDFHkeCrkmrwdr

MEQLAIHAESIVQMTGMFFKAAGSE-PGLQTGIVRTNCVDCLDRTNSAQFAIGKCALGHQLERLGFVKS-AKLEFDSDCVTMLENLYEEHGDTLALQYGG
.. |  . |. .. .|.|.| . ..    |.|.|||||.|||||||  |  ... .| .|||.||....  |||  ..  |.  ||. ...|... || |
lklLidqlekelsqegyflkseekkivkeqkgvvRtnCiDcLDRtnvvqsllarevLqkqleslgvlateskledsaeletsfknlwadnadavsvqYaG

SQLVHRikTYRKTAPWGSQG--SDVMQTLSRYYSNTFSDTEKQHSINLFLGIYKP
 .       . .|     .|   |.....|||| | |.| |.| ||.|||| |..
tgAlKt..DftRtGkrtllGalrDgvnsvsryyknnfldgerqdsidLflgkyrv