Gene CG17294 in Drosophila melanogaster

Synonym: Dmel\CG17294, Phos17294, Dmel_CG17294, CG17294

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold HAD
Superfamily HAD
Family NagD
Subfamily LHPP
Protein sequence
ID Type Fasta BLAST phosphatome Note
DmelP071_AA protein Get Run
DmelP071_AA_3-224 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
Hydrolase haloacid dehalogenase-like hydrolase 3-205 2.6e-07 22.6 Pfam-A 1-207 (215) alignment 
Range on Protein: 3-205
Range on HMM: 1-207/215.0
IKGALIDLSGTLhVEDEPTP---NAVEALKRLRDS---------GVLVKFVTNTTKDskATlherlcRIGFQLDASEIYSSLSAAVsYVENERLNPYYIL
||  ..|. ||| .| ||.    .. .||. ...            .|.. .. . .   .        ||. .. .  |     . . .|... .   |
iktvvfDktGTL.tegepsvallgnkaalalaaaletgsehpigkavvaaakanstr..gg......ltgfatfigrgvsgkvdgi.vlgnpewmtalgl

SEDARQDFPPEDTRRYKDSV-----VIGLAPKAFNYEQLNEAFNVLLENKNHKL-IAVHQGKYYKRAEGLALGPGC-F--VKGLEFatgrtakviGKPNP
 ..|  .. .|. .  . .|     .. |.  ||. .   || ... . |   . ...  |   . ||  |  .|     |..  .         |||.|
rviapdlvaaegqskgrtvvvvavqaralgviafadpvkpeaaeavasLkeaGievvlltgdnpetaeaiakqagiedslvfaevv.........gkPep

YFFEGALAG--RDPASCVMIGDDAND
  |. |.     ||  ..|.||. ||
klfvaaieeLqidpgevamvGDgvnD
Chronophin_1 4-224 8e-35 111.5 In-house 2-230 (261) alignment 
Range on Protein: 4-224
Range on HMM: 2-230/261.0
KGALIDLSGTLHVEDEPTPNAVEALKRLRDSGVLVKFVTNTTKDSKATLHERLCRIGFQ-LDASEIYSSLSAAVSYVENERLN-PYYILS-EDARQDFPP
. .|.|| | |  ..|  | | |....|.. |  | |||| ..  .. | .|| |.|.. . | ||.||  || .........   |.|  |  |...  
qlvLlDldGVlikgeeavpgAaeliealkqagkevlfvtNnsrrtreelaarlkrlGldavaaeeifssalaaaallrqqaakakvyvlGeeglrkelre

EDTRRYK------DSVVIGLAPkAFNYEQLNEAFNVLLENknHKLIAVHQGKYYKRAEGLALGPGCFVKGLEFATGRTAKVIGKPNPYFFEGALAGR--D
.  |  .      . ||.|  .  ...|.|.|| ... .    ...|  . ..  ..|| | | |  .  .| |.|| . |.|||.|. || ||  .  |
aGlrlvdepedrveaVvvGyde.elsfeklaeaialirdg..alfvatnrDptvPleeGiaPgtGslaaaveaAsgreplvvGKPepvmfeealekigad

PASCVMIGDDANDDIVGAMSMGMQGILVKTGK
|.. ||.||  . ||  .  .|.. .|| || 
peetvmvGDRldTDilagaraglstllvltGv
Chronophin_2 6-80 2.6e-08 24.5 In-house 3-78 (282) alignment 
Range on Protein: 6-80
Range on HMM: 3-78/282.0
ALIDLSGTLHVEDEPTPNAVEALKRLRDSGVLVKFVTNTTKDSKATLHERLCRIGF-QLDASEIYSSLSAAVSYVE
 |.|  | .   ..  . |.| ..||   |  | |||| .. ..  . ....|.|| .. | .|.||   .  |. 
vlfdcdgviwngekavagapevvsrlaragknvlfvtnnstrarenyvlkfarlgfadvaaeqifssaycsaaylr
subfamily_LHPP_pd Subfamily LHPP 7-228 6.7e-96 311.6 In-house 2-224 (227) alignment 
Range on Protein: 7-228
Range on HMM: 2-224/227.0
LIDLSGTLHVEDEPTPNAVEALKRLRDSGVLVKFVTNTTKDSKATLHERLCRIGFQLDASEIYSSLSAAVSYVENERLNPYYILSEDARQDFPPEDTRRy
|.||||.||.||...|.|||||||||..|| |.|||||||.||..|.|||.|.||.....||..||.||........|.||.....|...||   ||.. 
llDlsGvlhnedaaipgavealkrLrqagvkvrfvtNttkeskralverLirlgfdveeeeiftsleaarqllrerklrpyllveddveedfedidtdk.

KDSVVIGLAPKAFNYEQLNEAFNVLLENKNHKLIAVHQGKYYKRAEGLALGPGCFVKGLEFATGRTAKVIGKPNPYFFEGALA--GRDPASCVMIGDDAN
...|||||||..|.||.||.||..|||.|..||||...||||||..|||||||.|||.||.||| .|.|.|||...||| ||.  | ||...|||||| .
pnavviglapesfeyetlnqafrllleakkakliainkgkyykrkdGlalgpGafvkaleyatgvkaevvGKPsalffekaleelgvdpeeavmiGDdve

DDIVGAMSMGMQGILVKTGKYLPD
||. ||...|..|.||||||. |.
dDveGAlkaGlrgvlVktGkfrpe
Hydrolase_6 Haloacid dehalogenase-like hydrolase 7-93 1.2e-18 58.3 Pfam-A 2-90 (101) alignment 
Range on Protein: 7-93
Range on HMM: 2-90/101.0
LIDLSGTLHVEDEPTPNAVEALKRLRDSGVLVKFVTNTTKDSKATLHERLCRIGFQLDASEIYSSLSAAVSYVEN--ERLNPYYILSED
|.|. |.|. .|.. |.|.||||.||..|. | ..|| .. |.......| ..|..........| .||..|...  .. . . | .|.
lfDvdGvLwrgdkaipgaaealkalraagkpvvllTNnsskseeeyakkleklgvdvteeqvvtsataaaeylkkrkadkkvlvigeeg
subfamily_PGP_pd Subfamily PGP 7-91 2.7e-12 37.6 In-house 3-89 (279) alignment 
Range on Protein: 7-91
Range on HMM: 3-89/279.0
LIDLSGTLHVEDEPTPNAVEALKRLRDSGVLVKFVTNTTKDSKATLHERLCRIGFQ-LDASEIYSSLSAAVSYVENERLNP-YYILS
|.|  |.|  .... |.|.|||..|.. |  | ||||    |.. | ... ..||. .. .||.|| .|...| .... .   |.| 
lfDcDGVlWlgetaipgaaealnaLkklgKkvlfvtNnstksreellkkfkklgfekvkeeeilssaaaiadyLkqkkfekkvyvlg
subfamily_PGP_pd Subfamily PGP 109-224 3.2e-19 60.3 In-house 132-248 (279) alignment 
Range on Protein: 109-224
Range on HMM: 132-248/279.0
SVVIGLApKAFNYEQLNEAFNVLLENKnHKLIAVHQGKYYKRAEGLA-LGPGCFVKGLEFATGRTAKVIGKPNPYFFEGALA--GRDPASCVMIGDDAND
.||.|.  ....| .| .| |.| |..   ..|  . . .. ....   |.| .|. .| |.||.. |.||||.. .|  |     ||  ..||||  . 
AVvvgvd.eklsyakllkAanyLrepe.vlflatneDallplkkevvipgaGslvaaieaasgrkplvlGKPnelllelllekeeidpertlmiGDrlkt

DIVGAMSMGMQGILVKTGK
||  . . |.| .|| .| 
DilfgkncGlqtLlvlsGv
Chronophin_2 110-223 5.9e-14 43.0 In-house 129-243 (282) alignment 
Range on Protein: 110-223
Range on HMM: 129-243/282.0
VVIGLApKAFNYEQLNEAFNVlLENKNHKLIAVHQGKYYKRAEGLA-LGPGCFVKGLEFATGRTAKVIGKPNPYFFEGALA--GRDPASCVMIGDDANDD
|..|   . . . .| .|    | . .  |.|  .  ..  ..|    | | .   || |.|| | ||||| ...||        ||| ..||||  . |
vlvgyd.ekltflklakacay.lrdadclllatdrdpwhplsdgritpgsgsltaaletasgrkatvigkpsrfmfecissqfsvdparslmigdrletd

IVGAMSMGMQGILVKTG
|.     |.. .|  ||
ilfgsncglstvltltg
HAD_2 Haloacid dehalogenase-like hydrolase 171-220 3e-07 22.2 Pfam-A 127-176 (176) alignment 
Range on Protein: 171-220
Range on HMM: 127-176/176.0
RTAKViGKPNPYFFEGALA--GRDPASCVMIGDDAnDDIVGAMSMGMQGILV
  ...  ||.| ..| .|.  | .|  ...|.| . .|. .| ..|.....|
ddvga.pKpdpeayekvlerlgvkpeeilfidDsl.edveaAraaGirtvhv
Hydrolase_like HAD-hyrolase-like 176-245 1.1e-18 58.3 Pfam-A 2-75 (75) alignment 
Range on Protein: 176-245
Range on HMM: 2-75/75.0
IGKPNPYFFEGALAGR--DPASCVMIGDDANDDIVGAMSMGMQGILVKTGKYLPDVK--PSPPPTALLENFAEA
.||||| ... ||.    .|...|||||. ..|| .|  .|.. |||.|| . .. .  . . |.  .....||
lgKPnpgmydkalevlgappsevvmiGDslatDieaAnnaGirsilVltGvsreedlklakakpdyvvddleea
CECR5_TIGR01456 197-253 6.7e-06 15.7 In-house 305-362 (370) alignment 
Range on Protein: 197-253
Range on HMM: 305-362/370.0
VMIGDDANDDIVGAMSMGMQGILVKTGKYLP--DVKpSPPPTALLENFAEAVDWIIQKN
 |.||.   ||.||  .|.  |||||| |    . |   ... . ..  |||. |..|.
ymvGDnPasDiiGarnaGlfsilvktgvydgadelk.egkarlvvdsvseavikiLeke