Gene CG11291 in Drosophila melanogaster

Synonym: Dmel\CG11291, Phos11291, Dmel_CG11291, CG11291

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold HAD
Superfamily HAD
Family NagD
Subfamily PGP
Protein sequence
ID Type Fasta BLAST phosphatome Note
DmelP073_AA protein Get Run
DmelP073_AA_25-304 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_PGP_pd Subfamily PGP 26-305 3e-96 313.0 In-house 1-278 (279) alignment 
Range on Protein: 26-305
Range on HMM: 1-278/279.0
TIICSTDGVLWQENTPIEGSVEAFNAIISKGKRCLIATNECCLTNKDLFQKAKCLGFN-VKEQDIFSSSGAIASYLSDRKFKKKILVLGGDGIRKDLKEA
|.....|||||...|.|.|..||.||. ..||..|. ||... ....|..|.|.|||. |||..|.||. |||.||...||.||. ||| .|....||||
tvlfDcDGVlWlgetaipgaaealnaLkklgKkvlfvtNnstksreellkkfkklgfekvkeeeilssaaaiadyLkqkkfekkvyvlgeeglkeeLkea

GFCSVVNDL-QPNDQKKIDFVRSLVLDPDVGAVLVARDDNMIANELLVACNYLQNPKVLFLTTCIDGFQPFGK-KRIPDAGSLASAIEIIVQRKPIVLGK
|.... ..  . .|. . |||..| ||.|||||.|. |... ...|| |.|||..|.||||.|. | . |. | ..||.||||..|||....|||.||||
giellgtgpeklkdeldedfveelkldkdvgAVvvgvdeklsyakllkAanyLrepevlflatneDallplkkevvipgaGslvaaieaasgrkplvlGK

PNQRILGKLMKSGEIKPEKTLVIGNSLKSDILFASICGFQSLLVGCDNGAIEKAEKIKKEGdekkmKLVPDAFLSGLASFGEY
||...|  |... ||.||.||.||..||.||||.. ||.|.|||.... ..|..|.||||.     |||||..|. ||.. |.
PnelllelllekeeidpertlmiGDrlktDilfgkncGlqtLlvlsGvtkledveeikkee.....klvPdyyldsladllel
Chronophin_2 26-302 5.3e-54 174.4 In-house 2-276 (282) alignment 
Range on Protein: 26-302
Range on HMM: 2-276/282.0
TIICSTDGVLWQENTPIEGSVEAFNAIISKGKRCLIATNECCLTNKDLFQKAKCLGF-NVKEQDIFSSSGAIASYLSDR-KFKKKILVLGGDGIRKDLKE
...   |||.|. .. . |..|  . .. .||. |. ||..  . ... .|   ||| .|....||||.   | || |  . . |. |.||.|.||.|.|
nvlfdcdgviwngekavagapevvsrlaragknvlfvtnnstrarenyvlkfarlgfadvaaeqifssaycsaaylrdvadvrgkvfviggeglrkelre

AGFcSVVNDlqPNDQKkiDFVRSLVLDPDVGAVLVARDDNMIANELLVACNYLQNPKVLFLTTCIDGFQPFGK-KRIPDAGSLASAIEIIVQRKPIVLGK
||   ||.|  ...|.    . .  ||||| ||||  |...    |  || ||.... |.|.|  | . |. . ...| .|||..|.|.   || .|.||
agv.pvved..adeqe..asiydcaldpdvravlvgydekltflklakacaylrdadclllatdrdpwhplsdgritpgsgsltaaletasgrkatvigk

PNQRILGKLMKSGEIKPEKTLVIGNSLKSDILFASICGFQSLLVGCDNGAIEKAEKIKKEGDEKKMKLVPDAFLSGLASF
| . ..  . .  .. | ..|.||. |..|||| | ||....|      ..|.|.. ..    .. .|||| ..  .| .
psrfmfecissqfsvdparslmigdrletdilfgsncglstvltltgvssleeaqeysdsqlaeqrdlvpdyvvesiadl
Chronophin_1 27-304 1.2e-47 153.5 In-house 4-257 (261) alignment 
Range on Protein: 27-304
Range on HMM: 4-257/261.0
IICSTDGVLWQENTPIEGSVEAFNAIISKGKRCLIATNECCLTNKDLFQKAKCLGFN-VKEQDIFSSSGAIASYLSDRKFKKKILVLGGDGIRKDLKEAG
...  ||||..... ..|  |. .|.  .||..|. ||..  |...| .. | ||.. |... ||||  | |..|.. . | |..|||..|.||.|.|||
vLlDldGVlikgeeavpgAaeliealkqagkevlfvtNnsrrtreelaarlkrlGldavaaeeifssalaaaallrqqaakakvyvlGeeglrkelreaG

FCSVVNDLQpndqkkidfvrslvldpDVGAVLVARDDNMIANELLVACNYLQNPkVLFLTTCIDGFQPFGKKRIPDAGSLASAIEIIVQRKPIVLGKPNQ
.  | .. .                 .| ||.|  |...  ..|  |.......  ||. |  |   |  . ..| .|||| |.|   .|.|.| |||. 
lrlvdeped.................rveaVvvGydeelsfeklaeaialirdg.alfvatnrDptvPleeGiaPgtGslaaaveaAsgreplvvGKPep

RILGKLMKSGEIKPEKTLVIGNSLKSDILFASICGFQSLLVGCDNGAIEKAEKIKkegdekkMKLVPDAFLSGLASFGE
 .  . ... ...||.|...|  |  |||... .|...|||       |.|...|        .|.||| .. .| . |
vmfeealekigadpeetvmvGDRldTDilagaraglstllvltGvseleeaqayk.......kdlrPdavvesiadlle
subfamily_CUT_pd Subfamily CUT 27-131 1.1e-06 18.4 In-house 21-128 (391) alignment 
Range on Protein: 27-131
Range on HMM: 21-128/391.0
IICSTDGVLWQENTPIEGSVEAFNAIISKGK----RCLIATNECCLTNKDLFQK-AKCLGFNVKEQDIFSSSGAIASyLSDRkFKKKILVLGGDGIRKDL
|.   |||| ... .| .  ||.. .  |        .. ||   .|.|.  .| .. |...|. .... |   . . |... ..|..|| | .  |.  
ivlDiDGvLlRgkkvipaakealklledkkgelkvPvvfltnggnftekekaeklsekLdvevdadqvllshsPlkl.laek.ydkrllvvgqesvreva

KEAGFCSVVN
.  ||  ||.
eglGfknvvt
Subfamily.CECR5.protein 27-131 1.1e-06 18.4 In-house 23-130 (393) alignment 
Range on Protein: 27-131
Range on HMM: 23-130/393.0
IICSTDGVLWQENTPIEGSVEAFNAIISKGK----RCLIATNECCLTNKDLFQK-AKCLGFNVKEQDIFSSSGAIASyLSDRkFKKKILVLGGDGIRKDL
|.   |||| ... .| .  ||.. .  |        .. ||   .|.|.  .| .. |...|. .... |   . . |... ..|..|| | .  |.  
ivlDiDGvLlRgkkvipaakealklledkkgelkvPvvfltnggnftekekaeklsekLdvevdadqvllshsPlkl.laek.ydkrllvvgqesvreva

KEAGFCSVVN
.  ||  ||.
eglGfknvvt
Hydrolase_6 Haloacid dehalogenase-like hydrolase 28-126 1e-27 87.5 Pfam-A 2-100 (101) alignment 
Range on Protein: 28-126
Range on HMM: 2-100/101.0
ICSTDGVLWQENTPIEGSVEAFNAIISKGKRCLIATNECCLTNKDLFQKAKCLGFNVKEQDIFSSSGAIASYLSDRKFKKKILVLGGDGIRKDLKEAGF
..  |||||.....|.|..||..|. ..||.... ||.   ..... .| . ||..|.|.....|. |.|.||..||..||.||.|..|.|. ||||||
lfDvdGvLwrgdkaipgaaealkalraagkpvvllTNnsskseeeyakkleklgvdvteeqvvtsataaaeylkkrkadkkvlvigeeglreelkeaGf
CECR5_TIGR01456 28-131 6.6e-06 15.7 In-house 42-148 (370) alignment 
Range on Protein: 28-131
Range on HMM: 42-148/370.0
ICSTDGVLWQENTPIEGSVEAFNAIISK-GK---RCLIATNECCLTNKDLFQK-AKCLGFNVKEQDIFSSSGAIASyLSDrKFKKKILVLGGDGIRKDLK
.   |||| . . || |. .|.  .  . |.     |. ||   |...   .. .. || .|. . .  |   . . |.. |..|.||. |   ...  .
aldiDGvllrGkkpiagaskalrrLvddqGalkiPvllltngGglseraraeelsalLgvevsplqviqshsPykk.lvn.kyekrilasGkgevaevae

EAGFCSVVN
. ||  ||.
gyGFknvvt
subfamily_LHPP_pd Subfamily LHPP 32-266 6.3e-22 69.6 In-house 6-216 (227) alignment 
Range on Protein: 32-266
Range on HMM: 6-216/227.0
DGVLWQENTPIEGSVEAFNAIISKGKRCLIATNECCLTNKDLFQKAKCLGFNVKEQDIFSSSGAIASYLSDRKFKKKILVlgGDGIRKDLKEAGFCSVvn
 |||..|...| |.||| . . ..|..  . ||.   ....| .. . |||.|.|..||.|  |....| .|| .. .||   |. ..|...    .   
sGvlhnedaaipgavealkrLrqagvkvrfvtNttkeskralverLirlgfdveeeeiftsleaarqllrerklrpyllv..eddveedfedidtdkp..

dlqpndqkkidfvrslvldpdvGAVLVARDDNMIANE-LLVACNYLQN-PKVLFLTTCIDGFQPFGKKRIPDAGSLASAIEIIVQRKPIVLGKPNQRILG
                       || ..  .. . .| |  | . | . .|   ..   . .    .  . ..|. ..|.|  .. |  |.|||.. .  
......................navviglapesfeyetlnqafrllleakkakliainkgkyykrkdGlalgpGafvkaleyatgvkaevvGKPsalffe

KLMKSGEIKPEKTLVIGNSLKSDILFASICGFQSLLV
| ... ...||. ..|| ....|.  |  .|....||
kaleelgvdpeeavmiGDdvedDveGAlkaGlrgvlV
Hydrolase_like HAD-hyrolase-like 220-279 6.1e-11 33.5 Pfam-A 2-61 (75) alignment 
Range on Protein: 220-279
Range on HMM: 2-61/75.0
LGKPNQRILGKLMKSGEIKPEKTLVIGNSLKSDILFASICGFQSLLVGCDNGAIEKAEKI
|||||  .. | ..  ...|.....|| || .||..|  .| .|.||   ... |.... 
lgKPnpgmydkalevlgappsevvmiGDslatDieaAnnaGirsilVltGvsreedlkla