Gene CG32487 in Drosophila melanogaster

Synonym: CG2077, Dmel\CG32487, Phos32487, Dmel_CG32487, CG32487

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold HAD
Superfamily HAD
Family NagD
Subfamily PGP
Protein sequence
ID Type Fasta BLAST phosphatome Note
DmelP076_AA protein Get Run
DmelP076_AA_32-315 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
Hydrolase haloacid dehalogenase-like hydrolase 31-263 4.7e-08 25.0 Pfam-A 1-209 (215) alignment 
Range on Protein: 31-263
Range on HMM: 1-209/215.0
IDTIIFDGNGVLWSHGKVL--ENAAETFNALRAM--------GKKAFICTNNSVTSvEGiCKYAQEMGFLVAKNEILSSvqtlakfmkekK---------
|.|..||  |.|.   ...  .....  ....|.        ||.  ... .. |  .| . . ...    ... . .                      
iktvvfDktGTLtegepsvallgnkaalalaaaletgsehpigkavvaaakanstr.gg.ltgfatfigrgvsgkvdgi...........vlgnpewmta

-----FKKKCYVVGGQGIVDELKLVGIeslpldhsslqgfsmpdhihsiyldpNVGAVVVGSDKDFNTIKLTKACCYLRDSEV-MFVAT-------SRDA
     . ..   . || . ..   |..                          .. |. | .. |    .. .|. .|..  . ....|       ...|
lglrviapdlvaaegqskgrtvvvvav..........................qaralgviafadpvkpeaaeavasLkeaGievvlltgdnpetaeaia

ALPAApgrmvpsAGVMVAAIQAasqrmpftcGKPNPYMCIDLMQKGVIQPDRTLIIGDTMcTDIL
...         ....| |            |||.| .   ....  |.| ... .||.  .|. 
kqagi.......edslvfaevv.........gkPepklfvaaieeLqidpgevamvGDgv.nDap
subfamily_PGP_pd Subfamily PGP 33-314 5.3e-108 351.5 In-house 1-278 (279) alignment 
Range on Protein: 33-314
Range on HMM: 1-278/279.0
TIIFDGNGVLWSHGKVLENAAETFNALRAMGKKAFICTNNSVTSVEGICKYAQEMGFL-VAKNEILSSVQTLAKFMKEKKFKKKCYVVGGQGIVDELKLV
|..||..||||.. .....|||..|||...|||....||||..| | ..|.....||  | ..|||||....|...|.|||.||.||.| .|. .||| .
tvlfDcDGVlWlgetaipgaaealnaLkklgKkvlfvtNnstksreellkkfkklgfekvkeeeilssaaaiadyLkqkkfekkvyvlgeeglkeeLkea

GIESLPLDHSSLQGFSMPDHIHSIYLDPNVGAVVVGSDKDFNTIKLTKACCYLRDSEVMFVATSRDAALPAAPGRMVPSAGVMVAAIQAASQRMPFTCGK
|||.|  ....|..  ..|..... ||..||||||| |......||.||..|||..||.|.||..||.||.. ....|.|| .||||.|||.|.|...||
giellgtgpeklkdeldedfveelkldkdvgAVvvgvdeklsyakllkAanyLrepevlflatneDallplkkevvipgaGslvaaieaasgrkplvlGK

PNPYMCIDLMQKGVIQPDRTLIIGDTMCTDILLGYKCGFQTLLVGTGVNSYQDAIEAQGSKapllyQQVPDLYMPKLSNLLPF
||....  |..|  |.|.|||.|||...||||.| .||.|||||..||....|. |.. ..     ..|||.|...|..||..
PnelllelllekeeidpertlmiGDrlktDilfgkncGlqtLlvlsGvtkledveeikkee.....klvPdyyldsladllel
Chronophin_1 33-312 1.2e-60 196.1 In-house 3-256 (261) alignment 
Range on Protein: 33-312
Range on HMM: 3-256/261.0
TIIFDGNGVLWSHGKVLENAAETFNALRAMGKKAFICTNNSVTSVEGICKYAQEMGFL-VAKNEILSSVQTLAKFMKEKKFKKKCYVVGGQGIVDELKLV
....| .|||.  ..... |||. .||.  ||.... ||||..  | . .  ...|.  ||..||.||. . |....... | | ||.|..|...||.  
lvLlDldGVlikgeeavpgAaeliealkqagkevlfvtNnsrrtreelaarlkrlGldavaaeeifssalaaaallrqqaakakvyvlGeeglrkelrea

GIESLPLDHSslqgfsmpdhihsiyldpNVGAVVVGSDKDFNTIKLTKACCYLRDSeVMFVATSRDAALPAAPGrMVPSAGVMVAAIQAASQRMPFTCGK
|.     ..                   .| ||||| |....  ||..|....||.  .|||| ||   |.. | ..|..| ..||..|||.| |   ||
Glrlvdeped..................rveaVvvGydeelsfeklaeaialirdg.alfvatnrDptvPleeG.iaPgtGslaaaveaAsgreplvvGK

PNPYMCIDLMQKGVIQPDRTLIIGDTMCTDILLGYKCGFQTLLVGTGVNSYQDAIEAQgskapllYQQVPDLYMPKLSNLL
|.|.|    ..|  ..|..|...|| . |||| | ..|..|||| ||| . ..| ...        . .|| .. ....||
PepvmfeealekigadpeetvmvGDRldTDilagaraglstllvltGvseleeaqayk.......kdlrPdavvesiadll
Chronophin_2 33-315 2.4e-59 191.9 In-house 2-280 (282) alignment 
Range on Protein: 33-315
Range on HMM: 2-280/282.0
TIIFDGNGVLWSHGKVLENAAETFNALRAMGKKAFICTNNSVTSVEGICKYAQEMGFL-VAKNEILSSVQTLAKFMKE-KKFKKKCYVVGGQGIVDELKL
...|| .||.|   |..  |.|  . |  .||. .. ||||  . | . .    .||  ||...|.||    |.....  . . | .|.||.|.  ||. 
nvlfdcdgviwngekavagapevvsrlaragknvlfvtnnstrarenyvlkfarlgfadvaaeqifssaycsaaylrdvadvrgkvfviggeglrkelre

VGIESLplDHSSLQGfsmpDHIHSIYLDPNVGAVVVGSDKDFNTIKLTKACCYLRDSEVMFVATSRDAALPAAPGRMVPSAGVMVAAIQAASQRMPFTCG
 |.. .  .... |       |... |||.| ||.|| |...  .||.|||.||||.. ...|| ||   | . ||..| .| . ||...|| |     |
agvpvv..edadeqe....asiydcaldpdvravlvgydekltflklakacaylrdadclllatdrdpwhplsdgritpgsgsltaaletasgrkatvig

KPNPYMCIDLMQKGVIQPDRTLIIGDTMCTDILLGYKCGFQTLLVGTGVNSYQDAIEAQGSKAPLLYQQVPDLYMPKLSNLLPFL
|| ..|   . ..  ..| |.|.||| . ||||.| .||..|.|  ||| | ..| | . |...   . ||| ..  ...||. |
kpsrfmfecissqfsvdparslmigdrletdilfgsncglstvltltgvssleeaqeysdsqlaeqrdlvpdyvvesiadlleal
Hydrolase_6 Haloacid dehalogenase-like hydrolase 34-134 7.3e-28 87.9 Pfam-A 1-101 (101) alignment 
Range on Protein: 34-134
Range on HMM: 1-101/101.0
IIFDGNGVLWSHGKVLENAAETFNALRAMGKKAFICTNNSVTSVEGICKYAQEMGFLVAKNEILSSVQTLAKFMKEKKFKKKCYVVGGQGIVDELKLVGI
..||  ||||   |....|||...||||.||. ...||||  | |...|  ...|. |.......| . .|...|..|..||..|.|..|. .||| .|.
flfDvdGvLwrgdkaipgaaealkalraagkpvvllTNnsskseeeyakkleklgvdvteeqvvtsataaaeylkkrkadkkvlvigeeglreelkeaGf

E
.
k
subfamily_LHPP_pd Subfamily LHPP 35-280 2.3e-24 77.6 In-house 2-221 (227) alignment 
Range on Protein: 35-280
Range on HMM: 2-221/227.0
IFDGNGVLWSHGKVLENAAETFNALRAMGKKAFICTNNSVTSVEGICKYAQEMGFLVAKNEILSSVQTLAKFMKEKKFkkKCYVVGGQGIVDELKLVGIE
. |  |||.  .... .|.|  . ||. |.|  ..||.. .| . . .  ...|| | ..||..| .  .. ..|.|   ..|..  ..  .... .  .
llDlsGvlhnedaaipgavealkrLrqagvkvrfvtNttkeskralverLirlgfdveeeeiftsleaarqllrerkl..rpyllveddveedfedidtd

SlPldhsslqgfsmpdhihsiyldpnvGAVVVGSD-KDFNTIKLTKACCYLRD-SEVMFVATSRDAALPAAPGrMVPSAGVMVAAIQAASQRMPFTCGKP
. |                         |||.|.  . |.  .|..|   | . ..   .|  ..     . | .. ..|  |.|.. | .      |||
k.p........................navviglapesfeyetlnqafrllleakkakliainkgkyykrkdG.lalgpGafvkaleyatgvkaevvGKP

NPYMCIDLMQKGVIQPDRTLIIGDTMCTDILLGYKCGFQTLLVGTGVN
....  . ...  ..|.. ..||| .  |.    |.|....|| ||. 
salffekaleelgvdpeeavmiGDdvedDveGAlkaGlrgvlVktGkf
Hydrolase_like HAD-hyrolase-like 229-289 7.1e-15 46.1 Pfam-A 2-62 (75) alignment 
Range on Protein: 229-289
Range on HMM: 2-62/75.0
CGKPNPYMCIDLMQKGVIQPDRTLIIGDTMCTDILLGYKCGFQTLLVGTGVNSYQDAIEAQ
.||||| |    ...  . |.....|||.. |||. . ..| ...|| ||| . .|. .|.
lgKPnpgmydkalevlgappsevvmiGDslatDieaAnnaGirsilVltGvsreedlklak