subfamily_CDC14_pd |
Subfamily CDC14 |
17-337 |
4.7e-180 |
592.5 |
In-house |
8-328 (328) |
alignment |
Range on Protein: 17-337
Range on HMM: 8-328/328.0
SDRLYFATLRNRPKSTVNTHYFSIDEELVYENFYADFGPLNLAMVYRYCCKLNKKLKSYSLSRKKIVHYTCFDQRKRANAAFLIGAYAVIYLKKTPEEAY
.|||||||||..|||| ..||||.|.||.||||||||||||||..||||.|||||||| . ..||||.||..|..||||||.|||||||||||||.||||
edrlyfatlrkkPkstselhyfsvddelkyenfyadfGPlnlavlyrycvklnkkLkseekaskkivlytsadskkranaalligayaviylkktaeeay
RALLSGSNPPYLPFRDASFGNCTYNLTILDCLQGIRKGLQHGFFDFETFDVDEYEHYERVENGDFNWIVPGKFLAFSGPHPKSKIENGYPLHAPEAYFPY
||| ....||..||||||.|...|.||.||.|.|..|.||.||.|.|.||..|||.||||||||||||||.||||..|||.|||.|.||||||||....|
raleaaetppfvpfrdasygsasykltlldvlkgvekalqkgfldledfdleeYekyervenGDfnwivPdkflalagPhnkskledgyplhaPeklley
FKKHNVTAVVRLNKKIYEAKRFTDAGFEHYDLFFIDGSTPSDNIVRRFLNICENTEGAIAVHCKAGLGRTGTLIACYVMKHYRFTHAEIIAWIRICRPGS
|.|.|||.|||||||.|.||.||||||.|.||||||||||||.||..||.|.|..||||||||||||||||||||||.|||||||.||.|||.|||||||
frknnvttvvrLnkklYdakkftdaGfdhkDlffiDGstPsdaivkkfleiaekaeGaiavhCkaGLGrtGtLiacylmkhyrftaaeaiawlricrPGs
IIGPQQHFLEEKQASLWVQGD
.|||||.|||||||.||..||
vigpqqkfleekqaalwlegd
|
DSPn |
Dual specificity protein phosphatase, N-terminal half |
17-153 |
2.4e-63 |
203.0 |
Pfam-A |
5-140 (141) |
alignment |
Range on Protein: 17-153
Range on HMM: 5-140/141.0
SDRLYFATLRNRPKSTVNTHYFSIDEELVYENFYADFGPLNLAMVYRYCCKLNKKLKSYSLSRKKIVHYTCFDQRKRANAAFLIGAYAVIYLKKTPEEAY
|||||..|...||.| ||||||||||||||.|||||||||||..||.|.|||||||. .|..||||.||..|..||||||.||||||||.||..||||.
edrLyfvslkkkpkktenthyfsiDeelvYepfyadFGPlnlaqiyrfcvklnkkLkeaelkkkkivlytsldekkranaalLigaYavivlklspeeal
RALLSGSnPPYLPFRDASFGNCTYNLTILDCLQGIRK
..| |.. |..|||||||.|..||.|||||||.|..|
kplesve.psllpFrDAsygestyeltildclkglek
|
0048567 |
(Phosphotyrosine protein) phosphatases II |
17-163 |
1.6e-57 |
188.0 |
In-house |
12-157 (157) |
alignment |
Range on Protein: 17-163
Range on HMM: 12-157/157.0
SDRLYFATLRNRPKSTVNTHYFSIDEELVYENFYADFGPLNLAMVYRYCCKLNKKLKSYSLSRKKIVHYTCFDQRKRANAAFLIGAYAVIYLKKTPEEAY
||||||.|.. |||..|..|||||..||||.|..||||||||..||...||||.||...| .|.|.........||...|.|||.|....|..|||||.
pdrlyfallprlpkslynalyFsiddglvyedfffdfGPlnlailyrFilklnkflkilelagkaiavhckaglkkrgrtatLigcYlilhlgftpeeai
RALlSGSNPPYLPFRDASFGNCTYNLTILDCLQGIRKGLQHGFFDFE
. | . .|...||||||.....||||.||.|.|..|.|..||.|.|
apl.rivrpgsvpfrdasyllslynltlldvlyGllkAlelgfldle
|
0050432 |
(Phosphotyrosine protein) phosphatases II |
121-324 |
1.3e-42 |
141.6 |
In-house |
5-289 (308) |
alignment |
Range on Protein: 121-324
Range on HMM: 5-289/308.0
SGSNPPYLPFRDASFGNCTYNLTILDCLQGIRKGLQHGFFD------FETFDVDEYEHYERVENGDFNW-------------------------------
.. ...|.|||.|. .....|..||.|. . | |. |... ...... ||......||.|.|.
ldallelllfrdtsilvsslklsvldllkllekaldlglleeefeellsvkplleysvallpenkdkNrykdilpydhsRVkldegsdYInAsyvdgyss
IVPGKFLAFSGPHpkskiengypLHAPEAYFPYFKKHNVTAVVRLNKKIYE-----AKRFTDA---GFEHYDLFFI------------------------
..| ||.|. ||. . | .. .. ..||. .|.|.| .. |. . . |...|. |..
klprkfIatqgPl..........pntvedFwrmvweqnvrvIvmLtklvengrekcaqYwplelgggsleygkftvtllseevlddytvrtleltnlgdg
--------------DGSTPSD-NIVRRFLNICENT--EGAIAVHCKAGLGRTGTLIACYVM-----KHYRFTHAEIIAWIRICRPGSIIGPQQHF
|...|.. .|. .||...... .| |.|||.||.|||||.||.... |..... |.....| .|||....|.|..
esrtvthfhytnWpdhgvPpspeilldflelvrkslpggpivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkklReqRpgmvqtpeqyl
|
0045450 |
(Phosphotyrosine protein) phosphatases II |
124-323 |
1.5e-40 |
135.2 |
In-house |
2-293 (307) |
alignment |
Range on Protein: 124-323
Range on HMM: 2-293/307.0
NPPYLPFRDASFGNCTYNLTILDCLQGIRKGLQhGFFDFETFDVDEYEHYERVENGDFNWI---------------------------------------
..|. .|.|| .. . ..|..||.|.|..| . ......|...||......||.|.|..
dlplslfidalkllllvllllldfltgllkefe.kllsvtvfllgeysiallpenkdknrykdilpydhtRVklssldgsledsdYiNAsyvrvplllll
----VPGKFLAFSGPHPKskiengyplhAPEAYFPYFKKHNVTAVVRLNKKIYEAKR------------------------------------------F
.. ||.|. ||.|. .| .. ......||..|.|.. .. ... .
dgydlkrkfIatqgPlpe..........tvedFwrmlweqgvtvivmltelvelgrekcaqywPdegeeltygnftvtllseehldgytvrtlevtdldg
TDAGFEHYDLFF---IDGSTPSD-NIVRRFLNICEN------TEGAIAVHCKAGLGRTGTLIACYVMKHYR--------FTHAEIIAWIRICRPGSIIGP
|. ..... ... |...|.. ... .|...... .| ..|||.||.|||||.||.|.|.... .. |.....| .|||.. |
tgesrtvthfhytgwpdhgvppsfeelldfieevrkaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnp
QQH
.|
eqy
|
0049772 |
(Phosphotyrosine protein) phosphatases II |
126-333 |
1.6e-46 |
154.8 |
In-house |
65-271 (314) |
alignment |
Range on Protein: 126-333
Range on HMM: 65-271/314.0
PYLPFRDASFGNCTYNLTILDCLQGiRKGLQHGFFDFETFDVDEYEHYERVENGDFNWIVPGK---------------------FLAFSGPHpkskienG
|.||... .. |. | ..|.... .. |.....||....| .|.....|..||.|...... .| ..|.. .
pglpvsgsdyinasyvdgflkfIat.qgpleitvvdfreepvlyyngwrmvlrgdlnvrdivmsrdevladelsrLdaAlgKtpllildgng.......n
YPlhaPEAYFPYFKkhnvtavvrlnKKIYEAKRFTDAGFEHYDLFFIDGSTPSDNIVRRFLNICEN--TEGAIAVHCKAGLGRTGT-LIACYVMKHYRFT
.| ..|.....| . .|....|...|...... . |||.|.......||...|. ..|...|||||| ||||| ..|.|.||.....
ep...taadlellk...........eelydpelferlgikylripvpDgsaplledfdeflefieeadkggpvlvHCkaGkgRtgtfvvaaylmkllgvs
HAEIIAWIRICRPgsiIGPQQHFLEEKQASLW
.|.....| .|| |.|...|.| . ..
leealedvrlkRp...inpnpgfieqleqyef
|
0039614 |
(Phosphotyrosine protein) phosphatases II |
127-323 |
5e-40 |
133.2 |
In-house |
1-278 (297) |
alignment |
Range on Protein: 127-323
Range on HMM: 1-278/297.0
YLPFRDASFGNCTYNLTILDCLQGIRKGLQHGFFDFETFDV----DEYEHYERVENGDFNWIV------------------------------------P
|||.|||....... |..||.|....| .. .... | ... ..|......||.|.|... .
ylplrdallesipiplsvldlllllekansktllllefeellslkpdysiallpenkdknrykdilpydhsrvklkpedgvdldsdYinAsyvdgydllt
GKFLAFSGPHPKskiengyplhAPEAYFPYFKKHNVTAVVRLNKKIYEAK----------------------RFTDAGFEHYDLFF--------------
||.|..||.|. .| .. ......||..|.|.| .. . ....|. .. |
rkfIatqgPlpe..........tvedFwrmvweqgvtvivmLtklvelgrkcaqywpeeggtygdftvtllkvehldgytvrtlevtnngesrtvthfqy
---IDGSTP-SDNIVRRFLNICEN------TEGAIAVHCKAGLGRTGTLIACYVM-----KHYRFTHAEIIAWIRICRPGSIIGPQQH
|...| | ... .||..... .| ..|||.||.|||||.||.| | |..... |.....| .|||.. |.|
tgwpdhgvppslellleflelvrealaelpkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavqtpsqy
|
0043336 |
(Phosphotyrosine protein) phosphatases II |
137-322 |
2.4e-38 |
127.6 |
In-house |
4-265 (278) |
alignment |
Range on Protein: 137-322
Range on HMM: 4-265/278.0
NCTYNLTILDCLQGIRKGLQHGFFDFETFDVDEYEHYERVENGDFNWIV----------------------------------PGKFLAFSGPHPKskie
... ..|..| . ...|. .|... .|..|.|......||.|.|... | ||.|..||.|.
vkdllkallelllnlktllllefeellsfkldtysiallpenkdknrykdilpydhsrvklsllggdldsdYinAsyvdgynvprkfiatqgPlpe....
ngyplhAPEAYFPYFKKHNVTAVVRLNKKI--------------------------------------------YEAKRFTDAGFEHYDLFfiDGSTPSD
.| .. ......|| .|.|.. .. . .| .. ... |...|..
......tvedFwrmvwelgvttivmLtelvelgrvkcaqYwpggsltygdftvtllkeehlddytvrtlevtnlgdgesrtvthyhylgwp..dhgvpes
-----NIVRRFLNICENTEGAIAVHCKAGLGRTGTLIACYVM-----KHYRFTHAEIIAWIRICRPGSIIGPQQ
..........|. .|...|||.||.|||||.||.|.. |..... |.....| .|||.. |.|
lsllldflkavrealedsngpvlVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqRpgavqtpsq
|
0040438 |
(Phosphotyrosine protein) phosphatases II |
138-322 |
1.6e-40 |
134.7 |
In-house |
3-264 (317) |
alignment |
Range on Protein: 138-322
Range on HMM: 3-264/317.0
CTYNLTILDCLQGIRKGLQHGFFDFETFDVDEYEHYERVENGDFNWIV----------------------------------PGKFLAFSGPHPKskien
. ..|..||.|.. ..|. .|.|. ....|.|...|..||.|.|... . ||.|..||.|.
ldlllalldllksdftalleefedllslkldtysvaelpenkdknrypdilpydhsRVkLsplggdldsdYInAsyvdgpnlkrkfIatqgPlpn.....
gyplhAPEAYFPYFKKHNVTAVVRLNKKIYE------------------------AKRFTDAGFEHYDLFF-------------------IDGSTP-SDN
| .. ......|| .|.|.. . . ...||.... | . |...| | .
.....tvedFwrmvweqgvtvivmLteleelgrekcaqYwplgetltygdftvtllseeelagitlrtlevedlgdsesrtvthfhytgWpdhgvppspd
IVRRFLNICENT----EGAIAVHCKAGLGRTGTLIACYVM-----KHYRFTHAEIIAWIRICRPGSIIGPQQ
.. .||..... .| ..|||.||.|||||.||.|.| |..... |.....| .|||.. |.|
llldfleavrealedpggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeq
|
0045098 |
(Phosphotyrosine protein) phosphatases II |
152-334 |
3e-39 |
130.5 |
In-house |
7-273 (278) |
alignment |
Range on Protein: 152-334
Range on HMM: 7-273/278.0
RKGLQHGFFDFETFDVDEYEHYERVENGDFNWIV----------------------PGKFLAFSGPHPkskiengyplHAPEAYFPYFKKHNVTAVVRLN
. |. ..| . .....|.... ...|.|.|... | ||.|. ||.| . .... .......|..|.|.
ldlllefefllllgipseitpalylgnldknRykdilpydhsrVkdYINAsyidgypkkfIatqgPlp..........stvadfwrmlwelgitvivmlt
KKIYEA----------------------------------------------KRFTDAGFEHYDL-FFIDGSTPSDNIVRRFLNICE-------------
. .. . . .. .|..|... .. |...||..|.. ||...|
elvelgrekcaqywpeggsltygdftvtllseevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllasll
-------NTEGAIAVHCKAGLGRTGTLIACYVMKHY---RFTHAEIIAWIRICRPG-SI-IGPQQHFLEEKQASLWV
. .| ..|||.||.||||||.|.| |... ... |.....| .||| .. . |..||.| .. |.
lsslllldsggpvlVHCsaGvgRtGtlvaaylmlelleggvdlleavkelrsqRpglavqnleqyrflyefllelll
|
0044763 |
(Phosphotyrosine protein) phosphatases II |
160-337 |
1.7e-38 |
127.4 |
In-house |
2-175 (178) |
alignment |
Range on Protein: 160-337
Range on HMM: 2-175/178.0
FDFETFDVDEYEHYERVENGDFNWIVPGKFLAFSGPhpkskiengyplhapEAYFPYFKKHNVTAVVRLNKKIY------EAKRFTDAGFEHYDLFFIDG
.|. ......|..||... ....|.|| .|. .| .......|....|..|.|.. .. .. ...||.... . . |.
ldrtrvllsnleglersdyinaseilpglylgslpp...............addlellkelgithivnlteelelgflkcdpywpeeagiqylhipipDh
STPS-DNIVRRFLNICE----NTEGAIAVHCKAGLGRTGTLIACYVMKHYRFTHAEIIAWIRICRPGSIIGPQQHFLEEKQASLWVQGD
..|. . ....|....| . .|...|||.||.||.|||.|.| ||..... |.|...| .||... |...|.| . |. ..|
gvpdllehflefvefieealdekggpvlVHCsaGvgRsgtlvaaylmkklglsleeaielvrerRpivpnpgqlrqLyefelrllkesd
|
0047943 |
(Phosphotyrosine protein) phosphatases II |
163-323 |
2.3e-28 |
94.8 |
In-house |
23-261 (273) |
alignment |
Range on Protein: 163-323
Range on HMM: 23-261/273.0
ETFDVDEYEHYERVENGDFNWI------------------------------VPGKFLAFSGPHPKSkiengyplhaPEAYFPYFKKHNVTAVVRLNKKI
..... .|......||.|.|.. .. ||.|. || |.. | .. .....||. .|.|.. .
slkplltysvallpenkdknrykdilpydhsrvklgdggsdyinAsyvdgynlkrkfiatqgPlpnt..........vedfwrmvweqnvrviVmLtelv
YEAKR-----FTDAG---FEHYDLFFI--------------------------------------DGSTP-SDNIVRRFLNICEN------TEGAIAVHC
. .. . . | .. |. |.. | ..| | ... .|...... .| ..|||
elgrekcaqYwpleggelsltygkftvtllseetkddytvrtleltnlgtgesrtvthfhytgwpdhgvppslesllefielvrkalealpsngpvvVHC
KAGLGRTGTLIACYVM-----KHYRFTHAEIIAWIRICRPGSIIGPQQH
.||.|||||.||.... |..... |.....| .|||... |.|
saGvgRtgtfialdllldqlekeggvdvleavkllrsqRpgmvqtpeqy
|
0041856 |
(Phosphotyrosine protein) phosphatases II |
165-341 |
4.6e-45 |
148.8 |
In-house |
2-178 (182) |
alignment |
Range on Protein: 165-341
Range on HMM: 2-178/182.0
FDVDEYEHYERVENGDFNWIVPGKFLAFSGPHPKSKIENGYPLHAPEAYFPYFKKHNVTAVVRLNKKIYEAKRFTDAGFEHYDLFFIDGSTPSDNIVRRF
.| ..|... ..... ... . .....| |. . . .|..|. ........|....|..|.|. | .......|.....|.. |...|. ... .|
ldknrysdilpydhsrdldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlteelywpellerlgiqylylpwpDhgvpdldelldf
LNICENTEGAIAVHCKAGLGRTGTLIACYVMKHYRFTHAEIIAWIRICRPGSIIGPQQHFLEEKQASLWVQGDIFRS
...... .|...|||.||.||||||.|.|.||..... |.....| .|||..| |.|.|.. .. ........|.
ieevleeggpvlVHCsaGvgRtgtlvaaylmkklgvsleeavklvrsrRpgmvitpnqyfflqlallellllkktrp
|
0038934 |
(Phosphotyrosine protein) phosphatases II |
168-328 |
1.4e-44 |
147.4 |
In-house |
4-169 (194) |
alignment |
Range on Protein: 168-328
Range on HMM: 4-169/194.0
DEYEHYERVENgdfnwIVPGKFLAFSGPHPKSKIENGYPLH--APEAYFPYFKKH--NVTAVVRLN--KKIYEAKRFTDAGFEHYDLFFID-GSTPSDNI
|....||||.. |..|.|.||..|...| .. ..|. .|| .. |.| . ....|..|. .. |....|..||.|...|.|.| |..||..|
drwlkyervgd.....iitgrfiafkvPlsgsldkyieelyrfspedlvrylkllnvklglvidltnteryYdpeefekagieylklpfpddgtvPslei
VRRFLNIC-----ENTEGAIAVHCKAGLGRTGTLIACYVMKHYRFTHAEIIAWIRICRPGSIigPQQHFLEEK
..|||... |...|..||||||||||||||.|.| ....... | ||..|..|||.| |.|..||.
llrfldlvdeflnedpggvvaVHCkaGlgRtGtlvaaYLiyrlgmsaeeAialfrekRpgai..pnqdyleal
|
0043147 |
(Phosphotyrosine protein) phosphatases II |
168-326 |
5.9e-36 |
119.1 |
In-house |
2-153 (172) |
alignment |
Range on Protein: 168-326
Range on HMM: 2-153/172.0
DEYEHYERVENGDFNWiVPGKFLAFSGPhpkskiengyPLHAPEAYFPYFKKHNVTAVVRLNKKIYEAKRFTDAGFEHYDLFFIDGSTPSDNIVRRFLNI
||...|..... |... .| .|.|. || . . .. ..|....|..|.|.. | .. ... |.... | . |...|. .....||..
degsdyinasyldlyy.ipdrfiatqgp..........lrntladfwrmlkelgithivnltellydpellerlgiqylylpwpDhgvpllellleflef
CEN-----TEGAIAVHCKAGLGRTGTLIACYVMKhYRFTHAEIIAWIRICRPGSIIGPQQHFLE
... .|...|||.||.||||||.|.| |. .... |..|..| .|||.. |.|. .
idellalspggpvlVHCsaGvgRtgtlvaaylml.lglsleeavalvrekRpgavqnpsqyrfl
|
0040439 |
(Phosphotyrosine protein) phosphatases II |
169-322 |
1.1e-32 |
109.0 |
In-house |
2-234 (249) |
alignment |
Range on Protein: 169-322
Range on HMM: 2-234/249.0
EYEHYERVENGDFNWIV----------------------------------PGKFLAFSGPHPKskiengyplhAPEAYFPYFKKHNVTAVVRLNKKI--
||......||.| |... . .|.|..|| |. . |... .......|..|.|..
eysvallpenkdknrypdilpydhsrvklsilpglflsdyinAsyidgyyikrrfiatqgPlpe..........tvedfwrmlwelgitvivmLtslvel
-------------------------------------------YEAKRFTDAGFEHYDLFfiDGSTP-SDNIVRRFLNICEN------TEGAIAVHCKAG
|. . .| .. ..|. | ..| | ... .|...... ..| ..|||.||
grekcaqywplggsleygdftvtllsvevkddytvrtleltnlydgesrtvlhiqytdwp..dhgvppsfedlldfieavrkaleelpkggpvlVHCsaG
LGRTGTLIACYVM-----KHYRFTHAEIIAWIRICRPGSIIGPQQ
.|||||.||.| | |..... |.....| .|||.. |.|
vgRtGtfiaaylmleqlekelgvdleeavkllrsqRpgavqnpeq
|
PTEN_1 |
|
169-332 |
5.4e-32 |
106.2 |
In-house |
13-191 (196) |
alignment |
Range on Protein: 169-332
Range on HMM: 13-191/196.0
EYEHYERVENGDFNWIVPGKFLAFSGPHPKSKIENGY--PLHAPEAYFPYFKKHNVTAVVRLNK------KIYEAKRFTDAGFEHYDLFFIDGSTPSDNI
... | .... ... . ... |.| | .. .|. | .|. ..|.. .|....|.||.|. . |. . | . |.|.... . | .|| .
lalptelldltyitsriiamgkapsrpllqeideglyrgslkdvaadldnlkedgitlvvnlseeeelsgrsydleeffksgveylhfpieDhgapslse
VRRFLNICENT------EGAIAVHCKAGLGRTGTLIACYVMKHYRFTHAEIIAWIRICR-PGSIIGPQQHFLEEKQASL
. .... ... .....|||||||||.||..|.| |.....| | ....|..| ||.. |.| |.| .|.|
lfdicksfiewllsdpngnvVlVHCkaGlgRsGtvvaayLmykgkltadeAlelvrekRppgapnspsqerlleyfael
|
0042113 |
(Phosphotyrosine protein) phosphatases II |
170-323 |
2.9e-32 |
107.4 |
In-house |
1-232 (245) |
alignment |
Range on Protein: 170-323
Range on HMM: 1-232/245.0
YEHYERVENGDFNWI----------------------------------VPGKFLAFSGPHPKskiengyplhAPEAYFPYFKKHNVTAVVRLNKKIYE-
|......||.|.|.. ...||.|..||.|. .|... .......|..|.|.. .
ysvallpenkdknrysdilpydhtrvklspdggdldsdyinasyvdgyritpkfiatqgPlpe..........tvedfwrmlwelgittivmLteeeelg
------------------------------------------AKRFTDAGFEHYDLFFIDGSTPS-DNIVRRFLNICEN-----TEGAIAVHCKAGLGRT
. .. .. .. | . |...|. .... .||..... .| ..|||.||.|||
rvkcaqywplgesltygdftvtllseehlddytvrtlevtnlgddesrevihyhylpwpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRt
GTLIACYVM-----KHYRFTHAEIIAWIRICRPGSIIGPQQH
||.||.| | |..... |.....| .|||.. |.|
GtfiaaylmleqlekelgvsleeavkelrsqRpgavqtpsqy
|
0036282 |
(Phosphotyrosine protein) phosphatases II |
172-323 |
7.6e-32 |
105.8 |
In-house |
3-159 (174) |
alignment |
Range on Protein: 172-323
Range on HMM: 3-159/174.0
HYERVENGDFNWIVPgKFLAFSGPHPkskiengyplhapeaYFPYFKKHNVTAVVRLNKKIYEA------------KRFTDAGFEHYDLFFIDGSTPSDN
.|... . |...| | ...|..||.. .....|....|.||.|.. .. . ... |.....| . |...|...
dyinaspldlsyitp.rliagqgpla...............fwemlkelgittvvmlleekelglykcinywpelredlerlgiqylylpwpDhgvpdls
IVRRFLNICENT-----EGAIAVHCKAGLGRTGTLIACYVMKHYRF-THAEIIAWIRICR---PGSIIGPQQH
|...|....|. .| ..|||.||.||||||.|.| |... . . ......| .| ||... |.|
illefvkfveealsedpggpvlVHCsaGvgRtGtlvaaylmlrglleslvdaldlvrelRlqrpgmvqtpsQy
|
0046846 |
(Phosphotyrosine protein) phosphatases II |
175-323 |
1e-29 |
98.9 |
In-house |
6-162 (176) |
alignment |
Range on Protein: 175-323
Range on HMM: 6-162/176.0
RVENGDFNWIVPGKFLAFsgphpKSKIENGYPLHAPEAYFPYFKKHNVTAVVRLNKK--------IYEAKRFTDAGFEHYDLFFIDGSTPSDNIVRRFLN
.....|...|... .| . . | . .... ..|....||||.|.. . ......|.... | . |...|..... ..|.
lgldldldyinanlilgs.....rpiatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpeleklgiqylhlpwpDhgvpdlelllelle
ICENTE---GAIAVHCKAGLGRTGTLIACYVMKH-YRFTHAEIIAWIRICRP-GSIIGPQQH
.... | ..|||.||.||||||.|.| ... . .. |..|..| .|| |.. |.|
firealkeggpvlVHCsaGigRtgtlvaayllelekglsveealalvreqRplgavqtpeQy
|
0037934 |
(Phosphotyrosine protein) phosphatases II |
176-322 |
5.5e-32 |
106.7 |
In-house |
34-230 (243) |
alignment |
Range on Protein: 176-322
Range on HMM: 34-230/243.0
VENGDFNWIVPgKFLAFSGPHPKskiengYPLHAPEAYFPYFKKHNVTAVVRLNKKI------------------------------------------Y
|... ...| .. |..||.|. ....... .......|..| |.. . .
yinanliyvtp.rliatqgPlpe......tveddlasfwrmlwelgitvivmltelvElgrekcaqywpgevtygdftvtllseehlddytvrtlllenl
EAKRFTDAGFEHYDLFFIDGSTPS-DNIVRRFLNI------------CENTEGAIAVHCKAGLGRTGTLIACYVMKHY-RFTHAEIIAWIRICRPG-SII
... .| .. .. | . |...|. ... .||.. .....| ..|||.||.||||||||.|.|... ... |.....| .||| ..
dlddltrlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgRtGtliaaylmllllgvdleeavkllreqRpgkavq
GPQQ
|.|
tpsq
|
0048567 |
(Phosphotyrosine protein) phosphatases II |
176-227 |
5.6e-07 |
24.1 |
In-house |
2-58 (157) |
alignment |
Range on Protein: 176-227
Range on HMM: 2-58/157.0
VENGDFNWIVPGKFLAFSGPHPKSKIENGYPLHAPE--AYFPYFKKH---NVTAVVR
.||||...|.|........|.......| .... .. |...| .. |.. ..|
kengdlieiipdrlyfallprlpkslynalyFsiddglvyedfffdfGPlnlailyr
|
0051082 |
(Phosphotyrosine protein) phosphatases II |
180-326 |
1.6e-33 |
110.8 |
In-house |
7-145 (151) |
alignment |
Range on Protein: 180-326
Range on HMM: 7-145/151.0
DFNWIVPGkFLAFSGPHPkskiengyplhapeAYFPYFKKHNVTAVVRLNKKI---YEAKRFTDAGFEHYDLFFIDGSTPSD----NIVRRFLNICENT-
.|... .| .....||.. ......|.......| |... |........|.|.... ..| ..|. ..|..||......
nfsyvtgg.lyrsggpla..............dflellkelgiktivnlrseeergycpeylpelgievlhipildwpdpglplsfdavleflellldkk
EGAIAVHCKAGLGRTGTLIACYVMKhYRFTHAEIIAWIRICRPGSIIGPQQHFLE
.| ..|||.||.||||||.|.| |. .... .|.....|..|||... .||....
ngpvlvHCsaGkgRTGtlvalylml.lgvsleealeeyrlkrpgvvqpnqqflfq
|
0051429 |
(Phosphotyrosine protein) phosphatases II |
181-323 |
3.9e-21 |
71.4 |
In-house |
16-214 (272) |
alignment |
Range on Protein: 181-323
Range on HMM: 16-214/272.0
FNWIVPGKFLAFSGPHPKSkiengyplhapEAYFPYFKKHNVTAVVRLNKKIYEAK---RFTDAGFEHYDLFFIDGSTPSD-------------------
.....||.... .||.| . .| |...|.......| | . . .. . .|.... | ..| |.|.
grvvkpgrlyrsggplplt...........aadfwrlkelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseellldyi
---------------------------------NIVRRFLNICENtEGAIAVHCKAGLGRTGTLIACYVMKhYRFT--------------HAEIIAWIRI
. ....|... . .|.. |||.|| .||||..|.. . .... .|.....|
lrellltlllsagearevmhlhytdwpdhgvpqeallellellld.ggpvlvHCsaGkdRTGtvvalllll.lgvsletivddYlltnlyleeaveelra
CRPGSIIGPQQH
.|||.. ..|
qrpgavqteeqy
|
0046845 |
(Phosphotyrosine protein) phosphatases II |
183-323 |
2.9e-22 |
74.8 |
In-house |
73-263 (284) |
alignment |
Range on Protein: 183-323
Range on HMM: 73-263/284.0
WIVPGKFLAFSGPHPKskiengyplhAPEAYFPYFKKHNVTAVVRLNKKIYE-----------------------------------AKRF-------TD
.... ||.|..|| |. | .. ..||. .| |.. . .. |.
tyikkkfIatqgPlpn..........tvedFwrmvweqnvrvIVmltelvengrekcaqYwplegevltygdftvtllseevkddytvrtleltnlgytg
AGFEHYDLFFI---DGSTP-SDNIVRRFLNICENT------EGAIAVHCKAGLGRTGTLIACYVMKHY--------RFTHAEIIAWIRICRPGSIIGPQQ
.... . .. | ..| | ... .||..... .| |.|||.||.|||||.||....... ... |.....| .|||.. ..|
esrtvthfhytswpdhgvppspedlleflrlvrellenlpgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvqtleq
H
y
|
0051299 |
(Phosphotyrosine protein) phosphatases II |
185-323 |
1.4e-21 |
72.6 |
In-house |
90-275 (288) |
alignment |
Range on Protein: 185-323
Range on HMM: 90-275/288.0
VPGKFLAFSGPHPkskiengyplHAPEAYFPYFKKHNVTAVVRLNKKI------------------------YEAKRFTDAGFEHYDLFFI---------
. ||.|. || | . | .. . ..||. .|.|.| . . . ..... .. |
lkrkfIatqgPlp..........ntvedFWrmvweqnvrvIvmltklvelgrekcaqYwplggsltygditvtllseevlddytvrtlevtnldlldgdg
--------------DGSTPS-----DNIVRRFLNICENTEGAIAVHCKAGLGRTGTLIACYVM-----KHYRFTHAEIIAWIRICRPGSIIGPQQH
| ..|. ...|.. . .....| ..|||.||.|||||.||.... |..... |.....| .|||... |.|
esrtvthfhytnwpdhgvpdspellldflrlvrkalasgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlreqRpgmvqtpeqy
|
subfamily_RNGTT_pd |
Subfamily RNGTT |
185-327 |
5.1e-13 |
43.1 |
In-house |
14-166 (189) |
alignment |
Range on Protein: 185-327
Range on HMM: 14-166/189.0
VPGKFLAFSGPHP---KSKIENGYpLHAPEAYFPYFK--KHNVTAVVRLN--KKIYEAKRFTDAGFEHYDLFFI-DGSTPSDNIVRRFLNICEN-----T
. .|||.| | .... . . |. . |.| |... |. | .. |... ... | .. | | .|. . |..| ...|. .
iaekflpfktplskrydddlaeen.rfepsmllsylktlkvklglvidltntsryYdkeelekegikyvklqcagkgeaPeaeqvkefiklveeffkknp
EGAIAVHCKAGLGRTGTLIACYVMKHYRFTHAEIIAWIRICRPGSIIgpQQHFLEE
| |.|||. | ||| ||..|.... . . .| . .|| | ....|.|
eevigvhCthGfnRtGFlivsyLvekedwsveaavalFakaRppGiy..kedylke
|
0036941 |
(Phosphotyrosine protein) phosphatases II |
186-323 |
9.5e-20 |
66.5 |
In-house |
77-266 (297) |
alignment |
Range on Protein: 186-323
Range on HMM: 77-266/297.0
PGKFLAFSGPHPkskiengyplHAPEAYFPYFKKHNVTAVVRLNKKIYE---------------------------------AKRFTDAGFEHYD-----
. ||.| || | . | .. ..||| .| |.. . . .| .| .|
krkfIatqgPlp..........ntvedFWrmvweqnvtvIvmltelvelgrekcaqywpleegesltygdftvtllsvevvllddytlrtlevtdtgnge
---------LFFIDGSTPS-DNIVRRFLNICEN------TEGAIAVHCKAGLGRTGTLIACYVM--------KHYRFTHAEIIAWIRICRPGSIIGPQQH
. | ..|. ... .|.. ... .| . |||.||.||.||.||...| |..... |.. ..| .|||.. ..|
srtvthfhytgwpdhgvpespaslldfielvrkvlkllpsggpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqy
|
0049260 |
(Phosphotyrosine protein) phosphatases II |
208-326 |
9.2e-33 |
108.4 |
In-house |
20-142 (152) |
alignment |
Range on Protein: 208-326
Range on HMM: 20-142/152.0
HAPEAYFPYFKKHNVTAVVRLNKKIYEAKRFTDAGFEHYDLFFIDGSTPSDNIVRRFLNI-----CENTEGAIAVHCKAGLGRTGTLIACYVMKhYRFTH
. . .. ..|....|..|.|.. . .| ... ..... |.. |...|.. .. .||.. ... .| ..|||.||.||||||.|.| |. ....
ntladfwrmlkelgittivmltellelgklkceqyiqylhlpwpDhgvpdlsqlllflllfieklaldkggpvlVHCsaGvgRtgtlvaaylml.lgvsl
AEIIAWIRICRPGSIIGPQQHFLE
|..|..| .|||... |.| ..
eeavalvrekRpgavpnpgqlrfl
|
subfamily_PRL_pd |
Subfamily PRL |
212-330 |
1.4e-20 |
67.8 |
In-house |
25-147 (151) |
alignment |
Range on Protein: 212-330
Range on HMM: 25-147/151.0
AYFPYFKKHNVTAVVRLNKKIYEAKRFTDAGFEHYDLFFIDGSTPSDNIVRRFLNIC-----ENTEGAIAVHCKAGLGRTGTLIACYVMKHyRFTHAEII
. .||..|..||| . |... . ..| | || | ||..|....|...|... |... ..|||| |||||. |.| .. . ... . .
kfieelkkeevktvvrvceptydteklekegievldlafddGavPpeevveeWlellkekfkeepkstvavhcvaGlGraPvlvalaliea.Gmkyedav
AWIRICRPGSIIGPQQHFLEEKQA
.|| | |.| | .|||. .|
efirekrrgainskqlkflekyka
|
0048179 |
(Phosphotyrosine protein) phosphatases II |
213-324 |
4.8e-28 |
93.1 |
In-house |
21-136 (144) |
alignment |
Range on Protein: 213-324
Range on HMM: 21-136/144.0
YFPYFKKHNVTAVVRLNKKiYEAKRFTDAGFEHYDLFFIDGSTPSD-NIVRRFLNICENT---EGAIAVHCKAGLGRTGTLIACYVMKHYRFTHAEIIAW
....||...|.|..|. . || ... |.... | . | ..|.. .....||...|. .| ..|||.||.||||||.|.|.||..... |..|.
dlellkklgittvinltee.yepefleregiqylhlpwpDhgvpdllellleflefieealeeggpvlVHCsaGvgRtgtlvaaylmkklglsleealal
IRICRPGSIIGPQQ-HF
.| .|||... |.| .|
vrsrrpgavpnpgqlrf
|
subfamily_STYX_pd |
Subfamily STYX |
213-311 |
1.5e-06 |
21.4 |
In-house |
31-135 (166) |
alignment |
Range on Protein: 213-311
Range on HMM: 31-135/166.0
YFPYFKKHNVTAVVRLNKKIyEAKrFTDAGFE-HYDLFFID-GSTPSDNIVR------RFLNICENTEGAIAVHCKAGLGRTGTLIACYVMKHYRFTHAE
....||| .| .| . ..| ||. . |. .. . .| .. .||.| |.. . .. | . || .||. |. .|. .|.|. | . . |
klevlkkhgithivcirqni.ean.likpnfpdrfrylvldvadntveniirylptvkefiddslqkggkvlvhgnagisrsaalviayimetyglkyre
IIAWIRI
|...
afayvqe
|
0048076 |
(Phosphotyrosine protein) phosphatases II |
214-325 |
2.4e-27 |
90.8 |
In-house |
22-135 (145) |
alignment |
Range on Protein: 214-325
Range on HMM: 22-135/145.0
FPYFKKHNVTAVVRLnkkIYEAKRFTDAGFEHYDLFFIDGSTPSD-NIVRRFLNICENT---EGAIAVHCKAGLGRTGTLIACYVMKHYRFTHAEIIAWI
....|....|.|..| .| . ... |.... | . | ..|.. .....||...|. .| ..|||.||.||||||.|.|.|...... |.....
lellkdlgittvlnl...tselellerlgiqylylpwpDhgvpdllellleflefieealkeggpvlVHCsaGvgRtgtlvaaylmlllgvsleealelv
RICRPGSIIGPQQ-HFL
| .|||... |.| .||
rsqrpgavpnpgqlrfl
|
0048567 |
(Phosphotyrosine protein) phosphatases II |
215-333 |
2.8e-37 |
122.4 |
In-house |
10-138 (157) |
alignment |
Range on Protein: 215-333
Range on HMM: 10-138/157.0
PYFKKHNVTAVVRLNKKIYEAKRF-TDAGFEHYDLFFIDGstPSD--------NIVRRFLNICENTEGAIAVHCKAGL---GRTGTLIACYVMKHYRFTH
...........||.|..|.|. | .|.|. ..|.|| .| | . ... .||.|.|....|||||||||| |||.|||.|| ..|..||
iipdrlyfallprlpkslynalyFsiddglvyedfffdfG..PlnlailyrFilklnkflkilelagkaiavhckaglkkrgrtatLigcYlilhlgftp
AEIIAWIRICRPGSIIGPQQHFLEEKQASLW
.|.||..||.||||........|. .. ..
eeaiaplrivrpgsvpfrdasyllslynltl
|
PTPc_motif_SM00404 |
|
216-327 |
9.7e-16 |
52.9 |
In-house |
22-133 (140) |
alignment |
Range on Protein: 216-327
Range on HMM: 22-133/140.0
YFKKHNVTAVVRLNKKI---YEAKRFTDAGFEhYDLFFIDGSTPSDNIVRRFLNICENTEGAIAVHCKAGLGRTGTLIACYVMKHYRFTHAEIIAWIRIC
||...|.|. . ... .| ..|. . | | .. . | .|.. .|...|.. |||.||. |..|||..|.|. . .. || . ..
llkklgithvinvteevsltkensgfqilqip.lddnekdklskyldkvldfienaekkggkvlVHCqaGvSRSatliiaYlmryrqlslaeayefvker
RpgSIIGPQQHFLEE
| .|| |. .|...
R..piispnlnfvrq
|
subfamily_PTPMT1_pd |
Subfamily PTPMT1 |
217-315 |
1.8e-12 |
42.0 |
In-house |
42-150 (171) |
alignment |
Range on Protein: 217-315
Range on HMM: 42-150/171.0
FKKHNVTAVVRLNKKiYE-------AKRFTDAGFEHYDLFFIDGS-TPSDNIVRR---FLNICENTEGAIAVHCKAGLGRTGTLIACYVMKHYRFTHAEI
..|.|| ||| ||. || .... | |.. | .| .|. . . . |.. .. . |||||| ||..||.|||.||..... |
iekenvkavvslnee.yelkalansteewkklgveqlqlatvDfteapdleklekgvefiekvaskgkrvYvHCkaGrgRsatlvacylmkkeklspeeA
IAWIRICRPG
. .. .|.
lkalkkkRki
|
DSPc |
Dual specificity phosphatase, catalytic domain |
218-326 |
8e-14 |
46.7 |
Pfam-A |
15-125 (133) |
alignment |
Range on Protein: 218-326
Range on HMM: 15-125/133.0
KKHNVTAVVRLNKKIY-----EAKRFTDAGFEHYDlFFIDGSTPSDNIVRRFLNICENTEGAIAVHCKAGLGRTGTLIACYVMKHYRFTHAEIIAWIRIC
.|...|.|. . |.. . ..... . | . . .. . . .|.. .|. .. ..|||.||. |..|||..| || .... | .. ..
eklgitlvinvtkevpnnnaikkseieylripved.etetkiskeleeavefiekaeqkgkkvlVHCqaGisRSatliiaYlmktknlslneAyefvker
RpgSIIGPQQHFLE
| |.| |. .||
r..skispnagflr
|
DSPc |
Dual specificity phosphatase, catalytic domain |
218-326 |
8e-14 |
46.7 |
In-house |
15-125 (133) |
alignment |
Range on Protein: 218-326
Range on HMM: 15-125/133.0
KKHNVTAVVRLNKKIY-----EAKRFTDAGFEHYDlFFIDGSTPSDNIVRRFLNICENTEGAIAVHCKAGLGRTGTLIACYVMKHYRFTHAEIIAWIRIC
.|...|.|. . |.. . ..... . | . . .. . . .|.. .|. .. ..|||.||. |..|||..| || .... | .. ..
eklgitlvinvtkevpnnnaikkseieylripved.etetkiskeleeavefiekaeqkgkkvlVHCqaGisRSatliiaYlmktknlslneAyefvker
RpgSIIGPQQHFLE
| |.| |. .||
r..skispnagflr
|
subfamily_DSP1_pd |
Subfamily DSP1 |
218-325 |
1.5e-10 |
35.4 |
In-house |
40-146 (163) |
alignment |
Range on Protein: 218-325
Range on HMM: 40-146/163.0
KKHNVTAVVRLNKKIYEakRFTDaGFEHYDLFFIDGSTpSD-----NIVRRFLNICENTEGAIAVHCKAGLGRTGTLIACYVMKHYRFTHAEIIAWIRIC
|....||.. . |.. . | | ||.. | | .. | . | |.. .....| . .||.||. | ||. |.||. |.. | ...
kslgitailnvskeldn..vfed.lfeYkklkleDspk.adislvfeeviefidevkkknGkvlihCqaGisRsstlclaylmktkrvsleeafdfvkqr
RpgSIIGPQQHFL
| ||| | |
R..siisPnagFv
|
subfamily_DSP15_pd |
Subfamily DSP15 |
218-343 |
6.6e-09 |
30.0 |
In-house |
24-147 (151) |
alignment |
Range on Protein: 218-343
Range on HMM: 24-147/151.0
KKHNVTAVVRLNKkiyEAKRFTDAgfEHYDLFFIDGsTPSDNIV------RRFLNICENTEGAIAVHCKAGLGRTGTLIACYVMKHYRFTHAEIIAWIRI
|..|.| .. .. .||.. . .| .. .. ||| .. .|. | |... ||| ||. | ||.. |.| . . ... |.
keknithilsvhd...nakkllkd..ieYkciaasD.tpsaklskffkesvefihkcRlkeenvlvhClaGvsRsvtlvvaYlmtvtelnwrdalevika
CRpgSIIGPQQHFLEEKQASLWVQGDIFRSKL
.| |. | | . . . . . .| .|
aR..svanPnfGfkrqlkeyektklkeyrkql
|
subfamily_DSP19_pd |
Subfamily DSP19 |
218-326 |
6.8e-09 |
30.2 |
In-house |
34-141 (152) |
alignment |
Range on Protein: 218-326
Range on HMM: 34-141/152.0
KKHNVTAVVRLNKKIYEA--KRFTDAGFEHYDLFFIDGSTPSDNiVRRFLNICENTEGAIAVHCKAGLGRTGTLIACYVMKHYRFTHAEIIAWIRICRPG
|....| .. . .. .. | || | .|| | .. .. . |.. ...||. |||.|| |. ... |.||. . . | . .| ||
kekkitHilnvatgvpnvfpkdftylsieilDlpetdllsylke.aldFieearskdgavlvHCnAGvSRsasvviaylmkkeelsleealelvrearpc
siIGPQQHFLE
| | . |..
..ikPneGFik
|
PTPlike_phytase |
Inositol hexakisphosphate |
221-295 |
6e-07 |
24.2 |
Pfam-A |
74-147 (149) |
alignment |
Range on Protein: 221-295
Range on HMM: 74-147/149.0
NVTAVVRlnkKIYEAKRFTDAGFEHYDLFFIDGSTPSDNIVRRFLNICENTE--GAIAVHCKAGLGRTGTLIACYVM
..|.|. ..||.. .. |.. . . | . |... | .|........ |. ..|.|| ||| | .... .
tltevte...evyeeelaegfgvkYvRipitdeqapeeedvDafvrlikslprdtalvfnCqaGrgRTTtamviadL
|
PTPlike_phytase |
Inositol hexakisphosphate |
221-295 |
6e-07 |
24.2 |
In-house |
74-147 (149) |
alignment |
Range on Protein: 221-295
Range on HMM: 74-147/149.0
NVTAVVRlnkKIYEAKRFTDAGFEHYDLFFIDGSTPSDNIVRRFLNICENTE--GAIAVHCKAGLGRTGTLIACYVM
..|.|. ..||.. .. |.. . . | . |... | .|........ |. ..|.|| ||| | .... .
tltevte...evyeeelaegfgvkYvRipitdeqapeeedvDafvrlikslprdtalvfnCqaGrgRTTtamviadL
|
subfamily_PTPRK_pd |
Subfamily PTPRK |
223-296 |
7.8e-07 |
23.2 |
In-house |
163-234 (314) |
alignment |
Range on Protein: 223-296
Range on HMM: 163-234/314.0
TAVVRLNKKIYEAKRFTDAGFEHYDLFFIdgSTPSDNIVRRFLNICENTEGAIAVHCKAGLGRTGTLIACYVMK
. . | ..| | ..| |. ..| | ..||| . |...| | ||| || ||||| ||. ..
eklargqeeirevrqfqflgWpdhdvPvs..atgllklvrrvkksqeeeaGrivvhCsaGaGrtGtfiaidivl
|
subfamily_DSP3_pd |
Subfamily DSP3 |
226-326 |
1.6e-08 |
28.3 |
In-house |
51-148 (162) |
alignment |
Range on Protein: 226-326
Range on HMM: 51-148/162.0
VRLNKKIYEAKRFTDAGFEHYDLFFIDGSTPSDNIVRRFLNICENTEGAIAVHCKAGLGRTGTLIACYVMKHYRFTHAEIIAWIRICRPgsiIGPQQHFL
| ... |. .. |.| | . .| |. .. .. . ...|| . |||..|. | ||. |.| . ..| | | .| | |.| . ||
vdtgaefykdleikylGlevdDvpefdlskyFetaakfidealsqkegkvlvhcvvGvsRsatlvlayLmirrkmtlveairtvrkkRe...ilPneGFl
E
.
k
|
subfamily_DSP11_pd |
Subfamily DSP11 |
230-313 |
7.9e-10 |
32.9 |
In-house |
67-157 (178) |
alignment |
Range on Protein: 230-313
Range on HMM: 67-157/178.0
KKIYEAKRFTDAGFEHYDLFFIDGSTPSDNIVRR-------FLNICENTEGAIAVHCKAGLGRTGTLIACYVMKHYRFTHAEIIAWIRICR
.. |. | .|| | ... |. ..|....|.. ||. ..... |.||| |. ||| || |.... . . | .|
dryykkkeltdegvkylklncpGhevpkeelvkkfkeavkefleknkdndkligvhCthGvnrtGyliCrylidvegyepedaieafeear
|
subfamily_PTPDC1_pd |
Subfamily PTPDC1 |
233-322 |
2.1e-15 |
51.6 |
In-house |
73-164 (182) |
alignment |
Range on Protein: 233-322
Range on HMM: 73-164/182.0
YEAKRFTDAGFEHYDLFFIDGSTPSDNIVRRFLNICEN--TEGAIAVHCKAGLGRTGTLIACYVMKHYRFTHAEIIAWIRICRPGSIIGPQQ
|. . ....| .| . . | ...| . . . . .||..|||| ||||||| |||||.. . |.| .. | .| || || .|
YdlealmeqgiyvynfgwkDygvasleriLdivkvvafalqegkvavhChaGlGrtGvliacylvyakrltaekaiklvrskrpksiqtreq
|
subfamily_DSP23_pd |
Subfamily DSP23 |
252-322 |
2.9e-16 |
54.4 |
In-house |
61-134 (148) |
alignment |
Range on Protein: 252-322
Range on HMM: 61-134/148.0
DGSTPSDNIVRRFLNICENTE---GAIAVHCKAGLGRTGTLIACYVMKHYRFTHAEIIAWIRICRPGSIIGPQQ
| |. . | .|... |..| |..||| | |||||..|||..|. ... || || .| ||||. .|
dyhppaleqvvefvrvveeaeekneavsvhcllgrgrtgtmlacylvkerklaaaeaiaevrrlrpgsvetveq
|
subfamily_PTEN_pd |
Subfamily PTEN |
252-307 |
1.1e-09 |
33.6 |
In-house |
89-150 (184) |
alignment |
Range on Protein: 252-307
Range on HMM: 89-150/184.0
DGSTPSDNIVRRFLNI-----CENTEGAIAVHCKAGLGRTGTLIACYVMKHYRFTHA-EIIA
| .|. ........ |... ..|||||| ||||.||..|..|. ...| |...
DhnppplelleeivediekwleedkknvvvvHCkaGkGRtGvlivayllkslllekaeeale
|
subfamily_Cele-PTP-18_pd |
Subfamily Cele-PTP-18 |
252-296 |
9.4e-06 |
19.5 |
In-house |
199-244 (305) |
alignment |
Range on Protein: 252-296
Range on HMM: 199-244/305.0
DGSTPSDNIVRRFLNICENTEGAIAVHCKAGLGRTGTLIA-CYVMK
| ..|. . .|. . . | |.||| ||.||||... |...
rgvpaadlailellekarpskgpivvhcsagigrtgsvvmleyild
|
subfamily_Urchin-PTP-7_pd |
Subfamily Urchin-PTP-7 |
254-294 |
1.1e-06 |
22.8 |
In-house |
194-234 (315) |
alignment |
Range on Protein: 254-294
Range on HMM: 194-234/315.0
STPSDNIVRRFLNICENTEGAIAVHCKAGLGRTGTLIACYV
..| |..|. .|. ||| |||.|| |||||.|.
tiplmnlirtvkqhhtnsvgaivvhcsaGvGrtGtfitlda
|
subfamily_Cele-PTP-20_pd |
Subfamily Cele-PTP-20 |
257-317 |
1.1e-07 |
25.9 |
In-house |
200-266 (290) |
alignment |
Range on Protein: 257-317
Range on HMM: 200-266/290.0
SDN-IVRRFLNICENTEGAIAVHCKAGLGRTGTLIACYVM-----KHYRFTHAEIIAWIRICRPGSI
. . | | | .. | ..||| ||.|||||..| | . . .... .| .| .|.
lstlallrtlrilrkasGpvvvhcsaGiGrtGtfvaievglqilldGkeldlldlvralrnsrlnsv
|
subfamily_PTPN12_pd |
Subfamily PTPN12 |
259-294 |
6e-06 |
20.3 |
In-house |
194-229 (290) |
alignment |
Range on Protein: 259-294
Range on HMM: 194-229/290.0
NIVRRFLNICENTEGAIAVHCKAGLGRTGTLIACYV
.... . .. |. . ..||| || |||||.||
elielvrelqesedaPlvvhCsaGvGrtGtiiaidy
|
PTPc_DSPc_SM00012 |
|
260-298 |
5e-09 |
31.7 |
In-house |
21-65 (105) |
alignment |
Range on Protein: 260-298
Range on HMM: 21-65/105.0
IVRRFLNICE-------NtEGAIAVHCKAGLGRTGTLIACYVMKHY
. ..|. .. . .. . |||.|| |||||..| ... .
silellravkknknkses.skpvvVhCsaGvgRtgtfvaldillqq
|
Y_phosphatase |
Protein-tyrosine phosphatase |
260-316 |
5.7e-07 |
24.5 |
Pfam-A |
154-219 (235) |
alignment |
Range on Protein: 260-316
Range on HMM: 154-219/235.0
IVRRFLNICENTE----GAIAVHCKAGLGRTGTLIACYVMKHYRF-----THAEIIAWIRICRPGS
. .... .|... | . |||.|| |||||..| .. . .|. .| .|||.
slldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldilleqleaeeevdvlqivkelRkqRpgm
|
Y_phosphatase |
Protein-tyrosine phosphatase |
260-316 |
5.7e-07 |
24.5 |
In-house |
154-219 (235) |
alignment |
Range on Protein: 260-316
Range on HMM: 154-219/235.0
IVRRFLNICENTE----GAIAVHCKAGLGRTGTLIACYVMKHYRF-----THAEIIAWIRICRPGS
. .... .|... | . |||.|| |||||..| .. . .|. .| .|||.
slldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldilleqleaeeevdvlqivkelRkqRpgm
|
DSPc_SM00195 |
|
260-319 |
6.3e-07 |
24.4 |
In-house |
179-247 (263) |
alignment |
Range on Protein: 260-319
Range on HMM: 179-247/263.0
IVRRFLNICEN----TEGAIAVHCKAGLGRTGTLIACYVM-----KHYRFTHAEIIAWIRICRPGSIIG
|...|. ... ..| | |||.||.|||||... .. .. .. ||. .| |||..
svlellravkkskstssgpivVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqt
|
PTPc_SM00194 |
|
260-319 |
6.3e-07 |
24.4 |
In-house |
179-247 (263) |
alignment |
Range on Protein: 260-319
Range on HMM: 179-247/263.0
IVRRFLNICEN----TEGAIAVHCKAGLGRTGTLIACYVM-----KHYRFTHAEIIAWIRICRPGSIIG
|...|. ... ..| | |||.||.|||||... .. .. .. ||. .| |||..
svlellravkkskstssgpivVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqt
|
subfamily_Slingshot_pd |
Subfamily Slingshot |
262-327 |
3.4e-08 |
27.0 |
In-house |
86-149 (169) |
alignment |
Range on Protein: 262-327
Range on HMM: 86-149/169.0
RRFLNICENTEGAIAVHCKAGLGRTGTLIACYVMKHYRFTHAEIIAWIRICRpgSIIGPQQHFLEE
.|.. . ... . |||| |. |. . . | ||.|... | ..... | |.| | . ||.
ykfiekakkkgskvlvhckmGvsrsastviayamkeyglsleealeyvkerr..svikPnkgflkq
|
subfamily_PTPN6_pd |
Subfamily PTPN6 |
262-293 |
3.4e-06 |
21.3 |
In-house |
217-248 (306) |
alignment |
Range on Protein: 262-293
Range on HMM: 217-248/306.0
RRFLNICENTEGAIAVHCKAGLGRTGTLIACY
|. .. |...|.| ||| ||.|||||.|
rkqeeleeaeagpivvhCsaGiGRtGtfiviD
|
subfamily_DSP12_pd |
Subfamily DSP12 |
263-326 |
3.4e-09 |
31.3 |
In-house |
73-134 (155) |
alignment |
Range on Protein: 263-326
Range on HMM: 73-134/155.0
RFLNICENTEGAIAVHCKAGLGRTGTLIACYVMKHYRFTHAEIIAWIRICRPgsIIGPQQHFLE
.|.. . ..|||. |||.||. | |... |.||.... . . .. .| | | . |||
dFieealeeegavlvHCqagvSRSvtiviAYlmkkeklslekAlklvkekkp..eiepNegFle
|
subfamily_Cele-PTP-7_pd |
Subfamily Cele-PTP-7 |
263-322 |
3.3e-07 |
24.1 |
In-house |
212-276 (302) |
alignment |
Range on Protein: 263-322
Range on HMM: 212-276/302.0
RFLNICENTEGAIAVHCKAGLGRTGTLIAC-YVM----KHYRFTHAEIIAWIRICRPGSIIGPQQ
|. || .. ||| ||.||||||.| | . |. ..|. .| || |.. ||
dilkfcesykknvlvhcsaGvGrtGtlvaikyGiqlcskkkvtdllsivlpvrqcryGavqdeqq
|
subfamily_DSP8_pd |
Subfamily DSP8 |
263-326 |
1e-06 |
22.4 |
In-house |
84-145 (159) |
alignment |
Range on Protein: 263-326
Range on HMM: 84-145/159.0
RFLNICENTEGAIAVHCKAGLGRTGTLIACYVMKHYRFTHAEIIAWIRICRpgSIIGPQQHFLE
|.. . ...| . ||. || | |.. .|.||. ... | ... | | |. ||.
efidkaksengrvlvhvlaGisrsatvaiayimktlemsldeayrfvkekr..ptispnlnflg
|
subfamily_STYXL1_pd |
Subfamily STYXL1 |
263-327 |
6.6e-06 |
19.4 |
In-house |
83-145 (157) |
alignment |
Range on Protein: 263-327
Range on HMM: 83-145/157.0
RFLNICENTEGAIAVHCKAGLGRTGTLIACYVMKHYRFTHAEIIAWIRICRPGsiIGPQQHFLEE
.|... .... .. | . |. |. ..|..|.| ....|. . . .. |.. . |.. |.|
qfiekhkkegevvlvfsnkGisrsaaviiaylmyskkitlkkaykylkkCken..vkPnrafveq
|
subfamily_Choan-PTP-2_pd |
Subfamily Choan-PTP-2 |
263-331 |
7.5e-06 |
20.1 |
In-house |
189-261 (270) |
alignment |
Range on Protein: 263-331
Range on HMM: 189-261/270.0
RFLNICENTEgAIAVHCKAGLGRTGTLIAC-----YVMKHYRFTHAEIIAWIRICRPGSIIGPQQHFLEEKQAS
|. . ...| . ||| ||.|||||||| . .. . ..||. .| |. . |.| . | .
rsekeldkae.PllvHcsaGvgRtGtlialDiavrlLeetkkvdvlaiieelRkdRmalvqhpeqyeflykavv
|
subfamily_DSP10_pd |
Subfamily DSP10 |
264-325 |
4.7e-09 |
30.3 |
In-house |
84-143 (159) |
alignment |
Range on Protein: 264-325
Range on HMM: 84-143/159.0
FLNICENTEGAIAVHCKAGLGRTGTLIACYVMKHYRFTHAEIIAWIRICRPgsIIGPQQHFL
|.. ... . |||.||. | |.. |.||| . . . ... .|| || | |.
fieearkkgsrvLvhCqaGisrsatvviaYlmkhlnlslndaykfvkekrp..iisPnLnfm
|
subfamily_DSP6_pd |
Subfamily DSP6 |
264-326 |
2.4e-06 |
21.1 |
In-house |
85-145 (158) |
alignment |
Range on Protein: 264-326
Range on HMM: 85-145/158.0
FLNICENTEGAIAVHCKAGLGRTGTLIACYVMKHYRFTHAEIIAWIRICRpgSIIGPQQHFLE
|.. ... .. ||| ||. |. |.. .|.||.. .. . .... . | | | .|..
fidearskkskvlvhClaGisrsvtvtlaylmkklalslndaydlvkkrk..snisPnfnfmg
|
subfamily_Dicty-DSP19-like_pd |
Subfamily Dicty-DSP19-like |
266-327 |
2.7e-07 |
24.1 |
In-house |
85-144 (154) |
alignment |
Range on Protein: 266-327
Range on HMM: 85-144/154.0
NICENTEGAIAVHCKAGLGRTGTLIACYVMKHYRFTHAEIIAWIRICRPgsIIGPQQHFLEE
.| .. . ||...|. |. .|. |.|.. . . . . .. .|. || | | ||.
aiggvennkvlvhsdkGvsrsaallisylmdklkislslalellkdsry..iikPnqGflkq
|
subfamily_PTPN13_pd |
Subfamily PTPN13 |
266-314 |
1.5e-06 |
22.7 |
In-house |
196-249 (273) |
alignment |
Range on Protein: 266-314
Range on HMM: 196-249/273.0
NICENTEGAIAVHCKAGLGRTGTLIACYVM-----KHYRFTHAEIIAWIRICRP
. .. .| |.||| ||.||.||||. .|. . | ||. .| |
rrlqtdagPivvhcsaGiGrsGtlitidvvlglierdkefdvkeivrklreqrq
|
subfamily_DSP14_pd |
Subfamily DSP14 |
268-326 |
1.8e-07 |
25.3 |
In-house |
79-135 (157) |
alignment |
Range on Protein: 268-326
Range on HMM: 79-135/157.0
CENTEGAIAVHCKAGLGRTGTLIACYVMKHYRFTHAEIIAWIRICRPgsIIGPQQHFLE
....|.. |||.|| | .| |.||. . . .| ... .|| || | . | .
vkkkggktlvhCvaGvSRSAslclaylmkyeklsLreayklvksaRp..iirPNvGFwk
|
subfamily_Dicty-DSP-Subfam1_pd |
Subfamily Dicty-DSP-Subfam1 |
268-308 |
3.2e-06 |
19.9 |
In-house |
62-102 (128) |
alignment |
Range on Protein: 268-308
Range on HMM: 62-102/128.0
CENTEGAIAVHCKAGLGRTGTLIACYVMKHYRFTHAEIIAW
.. . |||. | ||| ..| ||||. . . . |
erelplvlyvhcecgcdrtgevlasyvmkykgydlkkalew
|
subfamily_Dicty-DSP19-1_pd |
Subfamily Dicty-DSP19-1 |
268-308 |
3.3e-06 |
19.9 |
In-house |
61-101 (128) |
alignment |
Range on Protein: 268-308
Range on HMM: 61-101/128.0
CENTEGAIAVHCKAGLGRTGTLIACYVMKHYRFTHAEIIAW
.. . |||. | ||| ..| ||||. . . . |
erelplvlyvhcecgcdrtgevlasyvmkykgydlkkalew
|
subfamily_VSP_pd |
Subfamily VSP |
269-304 |
7e-06 |
20.1 |
In-house |
125-160 (212) |
alignment |
Range on Protein: 269-304
Range on HMM: 125-160/212.0
ENTEGAIAVHCKAGLGRTGTLIACYVMKHYRFTHAE
.... .|.||| | |||||.. ..... |..|.
kdlknvlaihckGGkgrtGtivcalllaseifetak
|
subfamily_LRR-DSP_pd |
Subfamily LRR-DSP |
271-325 |
2e-06 |
21.1 |
In-house |
196-248 (263) |
alignment |
Range on Protein: 271-325
Range on HMM: 196-248/263.0
TEGAIAVHCKAGLGRTGTLIACYVMKHYRFTHAEIIAWIRICRPgsIIGPQQHFL
.| . |||.||. |. ||. .|.||. |.. | . . || | | . |.
kkGGvlvhcraGvsrsstlvisylmkkqrlkfkealdlvikkrp..riqPnpGfk
|