Gene SSH1 in Homo sapiens

Synonym: SSH1L, SSH1

Gene expression: GTEx, DEPOD

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family DSP
Subfamily Slingshot
Protein sequence
ID Type Fasta BLAST phosphatome Note
HsapP041_AA protein Get Run
HsapP041_AA_306-451 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_LRR-DSP_pd Subfamily LRR-DSP 226-447 6.7e-31 101.3 In-house 38-258 (263) alignment 
Range on Protein: 226-447
Range on HMM: 38-258/263.0
AMQDLESTRPDSPALFVDKPTEGERTERLIKAKLRSIMMSQDLENVTsKEIRNELEKQMNCNLKELK-EFIDNEMLLILgQMDKPSLIFDHLYLGSEWNA
. ....|   ||     ..  . .  .   | ..  .. | .||      . .||. . | .|  |  |. . | |..| .   |..| |.|.||.   |
tcnninsnnndsnnsnnnnnnnndnnnncnknnileminsteleggg.lgclkelnirdnrelislpveykqveslitl.vssvPdeiidklflGgldsa

SNLEELQGSGVDYILNVTREIDNFFPGLFAYHNI-RVYDEETTDLLAHWNEAYHFINKAkRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYV
 |   |.  || .||    ... .|| || |  |  . | .  |.  |..|   ||..  |..   ||||. |||||.. ||.| ||     ...|.. |
nnksilkdlgvthillavadfePlfPklfkylsiddiedvdeadisqhfeetnafieeG.rkkGGvlvhcraGvsrsstlvisylmkkqrlkfkealdlv

KQKRSITRPNAGFMRQLSEYEGIL
..||.  .|| ||. ||  ||  |
ikkrpriqPnpGfkdqlkkyekkl
DEK_C DEK C terminal domain 251-303 1.2e-18 56.3 Pfam-A 1-53 (54) alignment 
Range on Protein: 251-303
Range on HMM: 1-53/54.0
TERLIKAKLRSIMMSQDLENVTSKEIRNELEKQMNCNLKELKEFIDNEMLLIL
|.. ||...| |....|||.||.|..| |||......|.| |.||....  .|
tdeeikeevreiLkeaDLetvTkkqvrkeLearlgvdLserKafIkdlieefL
subfamily_Slingshot_pd Subfamily Slingshot 292-459 1.1e-94 308.5 In-house 2-169 (169) alignment 
Range on Protein: 292-459
Range on HMM: 2-169/169.0
KEFIDNEMLLILGQMDKPSLIFDHLYLGSEWNASNLEELQGSGVDYILNVTREIDNFFPGLFAYHNIRVYDEETTDLLAHWNEAYHFINKAKRNHSKCLV
|||||||||.||||.|..| ||||.||||||||||||||. .||.||||||.|||||||. |.|.||||||||.||||..|||.|.||.|||...||.||
kefidnemlvilgqldsaskifdhvylGsewnasnleelkengveyilnvtkeidnffpekfeylnirvydeeetdllkywnetykfiekakkkgskvlv

HCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQKRSITRPNAGFMRQLSEYEGILDASKQRHNKLWR
||||||||||||||||||||.|. ||.|..|||..||...||.||..||.||||||.|||||||||.|
hckmGvsrsastviayamkeyglsleealeyvkerrsvikPnkgflkqleeyeGileaskqrhnklfr
0044763 (Phosphotyrosine protein) phosphatases II 296-447 1.9e-41 137.0 In-house 10-170 (178) alignment 
Range on Protein: 296-447
Range on HMM: 10-170/178.0
DNEMLLILGQMDKPSLIFDHLYLGSEWNASNLEELQGSGVDYILNVTREIDNFFPGL---------FAYHNIRVYDEETTDLLAHWNEAYHFINKAK-RN
.| . |  ...  .| |...||||| ..|..|| |.  |...|.|.| |. ..|...         . |..| . |  ..|||.|. |...||..|  ..
snleglersdyinaseilpglylgslppaddlellkelgithivnlteelelgflkcdpywpeeagiqylhipipDhgvpdllehflefvefieealdek

HSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQKRSiTRPNAGFMRQLSEYEGIL
....||||..||.||.. |.|| ||..|..||.|...|...|.   || |..||| |.| .|
ggpvlVHCsaGvgRsgtlvaaylmkklglsleeaielvrerRp.ivpnpgqlrqLyefelrl
0049772 (Phosphotyrosine protein) phosphatases II 304-458 5e-37 123.7 In-house 149-284 (314) alignment 
Range on Protein: 304-458
Range on HMM: 149-284/314.0
GQMDKPSlifdhlylgSEWNASNLEELQgsgvdyilnvtREI--DNFFPGL-FAYHNIRVYDeETTDLLAHWNEAYHFINKAkRNHSKCLVHCKMGVSRS
 ..| .          .|..|..||.|.           .|.  ...|..| . |..| |.| ....||....|...||..| ..... |||||.|..|.
lildgng.........neptaadlellk...........eelydpelferlgikylripvpD.gsaplledfdeflefieea.dkggpvlvHCkaGkgRt

AS-TVIAYAMKEFGWPLEKAYNYVKQKRSiTRPNAGFMRQLSEYEGILDASKQRHNKLW
..  |.|| || .|..||.|...|..||.  .|| ||..|| .|| ||.|.... ..|.
gtfvvaaylmkllgvsleealedvrlkRp.inpnpgfieqleqyefilealleylkflk
0045098 (Phosphotyrosine protein) phosphatases II 306-444 2.9e-26 87.9 In-house 19-268 (278) alignment 
Range on Protein: 306-444
Range on HMM: 19-268/278.0
MDKPSLIFDHLYLGSEW-----------------------------------------NASNLEELQGSGVDYILNVTREIDN-----------------
.  || |...||||. .                                          |.... |.  |. .|...|.....                 
lgipseitpalylgnldknRykdilpydhsrVkdYINAsyidgypkkfIatqgPlpstvadfwrmlwelgitvivmltelvelgrekcaqywpeggslty

-----------------------------------FFPGLFAYHNIRVYDEETTDLLAHWNEAYHFINKAKR--------------NHSKCLVHCKMGVS
                                   ..   . |...  ..  ....|... |.. ||..| .              .. ..||||..||.
gdftvtllseevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllsslllldsggpvlVHCsaGvg

RSASTVIAYAMKEF---GWPLEKAYNYVKQKRSI-TRPNAGFMRQLSEYE
|..  |.|| |.|    |. |..|.......| .   .| ...|.| |..
RtGtlvaaylmlelleggvdlleavkelrsqRpglavqnleqyrflyefl
subfamily_DSP8_pd Subfamily DSP8 307-448 4.4e-32 104.8 In-house 13-155 (159) alignment 
Range on Protein: 307-448
Range on HMM: 13-155/159.0
DKPSLIFDHLYLGSEWNASNLEELQGSGVDYILNVTRE-IDNFFPGLFAYHNIRVYDEETTDLLAHWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVI
..|  | ..|||||. .. . | |.  |..|.||. .. ..  .     .. . | |. . .||  ......||.|||......|||.  | ||||. .|
vgptrilknlylGsqkdvlseellsklgisyvlnasnscpkleelkeskflrvPvkDkydekllpwfdksvefidkaksengrvlvhvlaGisrsatvai

AYAMKEFGWPLEKAYNYVKQKRSITRPNAGFMRQLSEYEGILD
|| ||..   |..||..||.||    ||  |. || |||  | 
ayimktlemsldeayrfvkekrptispnlnflgqLleyekelk
subfamily_DSP1_pd Subfamily DSP1 308-448 4e-48 157.6 In-house 16-157 (163) alignment 
Range on Protein: 308-448
Range on HMM: 16-157/163.0
KPSL-IFDHLYLGSEWNASNLEELQGSGVDYILNVTREIDNFFPGLFAYHNIRVYDEETTDLLAHWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIA
 |.  | |.|||||| .||||| |.  |.  ||||..|.||.|. || |... . |... |. ....|. .||...|... | |.||..|.|||.. ..|
dPvekildfLylGsetvasnleiLkslgitailnvskeldnvfedlfeYkklkleDspkadislvfeeviefidevkkknGkvlihCqaGisRsstlcla

YAMKEFGWPLEKAYNYVKQKRSITRPNAGFMRQLSEYEGILD
| ||.  . ||.|...|||.||| .|||||..|| .||  | 
ylmktkrvsleeafdfvkqrRsiisPnagFvlqLlnyekkll
subfamily_DSP6_pd Subfamily DSP6 308-449 3.6e-41 134.3 In-house 13-156 (158) alignment 
Range on Protein: 308-449
Range on HMM: 13-156/158.0
KPSLIFDHLYLGSEWNASNLEELQGSGVDYILNVTREIDNFFP--GLFAYHNIRVYDEETTDLLAHWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVI
 |  | ..|||||. .||||| |. ... |.|||| ...|.|   | . | .| . |. ...| ... || .||..|....||.||||  |.|||   ..
fpveilpllylGsakdasnlevlkklkikyvlnvtsnlpnkfeesgelkylqipiedhlsqnlakffPeaiefidearskkskvlvhClaGisrsvtvtl

AYAMKEFGWPLEKAYNYVKQKRSITRPNAGFMRQLSEYEGILDA
|| ||.    |..||..||...|   ||  || || ..|  |  
aylmkklalslndaydlvkkrksnisPnfnfmgqlldferslrl
PTPc_motif_SM00404 308-444 2.2e-39 129.5 In-house 1-138 (140) alignment 
Range on Protein: 308-444
Range on HMM: 1-138/140.0
KPSLIFDHLYLGSEWNASNLEELQGSGVDYILNVTREIDN-FFPGLFAYHNIRVYDEETTDLLAHWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIA
.|| | .||||||. .|.|.. |.  |.....|||.|...      | . .| . |.|...|........ ||..|.... |.||||..||||||. .||
epsrilphlylgskskaqnpallkklgithvinvteevsltkensgfqilqiplddnekdklskyldkvldfienaekkggkvlVHCqaGvSRSatliia

YAMKEFGWPLEKAYNYVKQKRSITRPNAGFMRQLSEYE
| |.. .. |..||..||..|.| .||..|.||| |||
YlmryrqlslaeayefvkerRpiispnlnfvrqLieye
0041856 (Phosphotyrosine protein) phosphatases II 308-447 8.5e-33 108.8 In-house 18-172 (182) alignment 
Range on Protein: 308-447
Range on HMM: 18-172/182.0
KPSLIFDHLYLGSEWN--------------ASNLEELQGSGVDYILNVTREI---DNFFPGLFAYHNIRVYDEETTDllahWNEAYHFINKAKRNHSKCL
 .. | ..||||| ..              |..|. |.. |. .|.|.| |    ...    . |... . | ...|    ..|...||....... ..|
dldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlteelywpellerlgiqylylpwpDhgvpd....ldelldfieevleeggpvl

VHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQKRS--ITRPNAGFMRQLSEYEGIL
|||..||.|... |.|| ||. |..||.|...|...|.  ...|| .|..|| ..| .|
VHCsaGvgRtgtlvaaylmkklgvsleeavklvrsrRpgmvitpnqyfflqlallelll
0046846 (Phosphotyrosine protein) phosphatases II 308-445 1.7e-27 91.7 In-house 11-170 (176) alignment 
Range on Protein: 308-445
Range on HMM: 11-170/176.0
KPSLIFDHLYLGSEW----------NASNLEELQGSGVDYILNVTREIDNFFP-------G----LFAYHNIRVYDEETTDLlAHWNEAYHFINKAKRNH
 .. | ..|.||| .           |..||.|.  |.....|.| |..  .              . |... . |  . || ... |.. ||..| ...
dldyinanlilgsrpiatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpeleklgiqylhlpwpDhgvpdl.elllellefirealkeg

SKCLVHCKMGVSRSASTVIAYAMKE-FGWPLEKAYNYVKQKRS-ITRPNAGFMRQLSEYEG
 . ||||..|..|..  |.|| ..  .|...|.|. .|...|.    .. ...|.| |.| 
gpvlVHCsaGigRtgtlvaayllelekglsveealalvreqRplgavqtpeQyrflyefel
PTEN_1 308-450 1.5e-26 88.4 In-house 38-194 (196) alignment 
Range on Protein: 308-450
Range on HMM: 38-194/196.0
KP--SLIFDHLYLGSEWNA-SNLEELQGSGVDYILNVTREIDN---------FFPGLFAYHNIRVYDEETTDLLAHWNEAYHFINKAKR--NHSKCLVHC
.|  . |...||.||.  . ..|..|...|.  ..|.. | ..         || . . |... . |  . .|  .. ... ||. ...  |. ..||||
rpllqeideglyrgslkdvaadldnlkedgitlvvnlseeeelsgrsydleeffksgveylhfpieDhgapslselfdicksfiewllsdpngnvVlVHC

KMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQKRSITRPNAGFMRQLSEYEGILDAS
| |..||.  |.|| |.  ..  ..|  .|..||.  .|| .....| ||.  | |.
kaGlgRsGtvvaayLmykgkltadeAlelvrekRppgapnspsqerlleyfaellae
subfamily_Dicty-DSP19-like_pd Subfamily Dicty-DSP19-like 308-444 9.9e-25 80.7 In-house 2-149 (154) alignment 
Range on Protein: 308-444
Range on HMM: 2-149/154.0
KPSLIFDHLYLGSEWNASNLEELQGSGVDYILNVTREIDNFFPGL---------FAYHNIRVYDEETTDLLAHWNEAYHFINKAK--RNHSKCLVHCKMG
..|    .||..|   | |  .||   .  ||||   |.| |.           . | |....|.   |.. . . |..||..|    ...| |||.. |
rnskeaiflyissfdaalnkldlqlkniksilnvgiGinnlftdensdindgfiieylnlelfddvnfdiiekldkafefiddaiggvennkvlvhsdkG

VSRSASTVIAYAMKEFGWPLEKAYNYVKQKRSITRPNAGFMRQLSEYE
|||||. .|.| |..   .| .|.  .|. | | .|| ||..||  .|
vsrsaallisylmdklkislslalellkdsryiikPnqGflkqleife
subfamily_DSP10_pd Subfamily DSP10 309-450 4.5e-44 144.1 In-house 14-156 (159) alignment 
Range on Protein: 309-450
Range on HMM: 14-156/159.0
PSLIFDHLYLGSEWNASNLEELQGSGVDYILNVTREIDNFFPG-LFAYHNIRVYDEETTDLLAHWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAY
 | .. .|.|||| .|..|. |.  .....|||| .. |.| .  . |. | | | .. .|  ...||..||..|... |. ||||. |.||||. ||||
asqvlpfLflGsekdaadldaldrlnitavlnvttsvPnefeeealkYkripvsDtskqnlkqyfeealefieearkkgsrvLvhCqaGisrsatvviaY

AMKEFGWPLEKAYNYVKQKRSITRPNAGFMRQLSEYEGILDAS
 ||...  |..||..||.||.|  || .|| || |.|  |. |
lmkhlnlslndaykfvkekrpiisPnLnfmGqLlefekelnks
0048076 (Phosphotyrosine protein) phosphatases II 309-446 1.2e-37 124.1 In-house 4-141 (145) alignment 
Range on Protein: 309-446
Range on HMM: 4-141/145.0
PSLIFDHLYLGSEWNASNLEELQGSGVDYILNVTREIDNFFPGLFAYHNIRVYDEETTDLLAHWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYA
|| |...||||| ..|..||.|.  |. ..||.|.|......  . |... . | .. |||... |...||..| ... ..||||..||.|... |.|| 
pseilpglylgslptaldlellkdlgittvlnltselellerlgiqylylpwpDhgvpdllellleflefieealkeggpvlVHCsaGvgRtgtlvaayl

MKEFGWPLEKAYNYVKQKRSITRPNAGFMRQLSEYEGI
|...|..||.|...|...|..  || |..|.| |.| .
mlllgvsleealelvrsqrpgavpnpgqlrflyefele
0048179 (Phosphotyrosine protein) phosphatases II 309-447 1.4e-37 124.0 In-house 4-144 (144) alignment 
Range on Protein: 309-447
Range on HMM: 4-144/144.0
PSLIFDHLYLGSEWNASNLEELQGSGVDYILNVTREIDNFFPGLF--AYHNIRVYDEETTDLLAHWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIA
|| |...||||| . |..||.|.  |.....|.| | .. |.. .   |... . | .. |||....|...||..| ... ..||||..||.|... |.|
pseilpglylgslptaldlellkklgittvinlteeyepefleregiqylhlpwpDhgvpdllellleflefieealeeggpvlVHCsaGvgRtgtlvaa

YAMKEFGWPLEKAYNYVKQKRSITRPNAGFMRQLSEYEGIL
| ||..|..||.|...|...|..  || |..|.| ||| .|
ylmkklglsleealalvrsrrpgavpnpgqlrfLleyekll
subfamily_MKPLT_pd Subfamily MKPLT 309-446 4.7e-33 108.0 In-house 21-159 (164) alignment 
Range on Protein: 309-446
Range on HMM: 21-159/164.0
PSLIF-DHLYLGSEWNASNLEELQGSGVDYILNVTREIDNFFPGLFAYHNIRVYDEETTDLLAHWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAY
||... |.||||   .| | . |.   ...|.||..|  . ||  . | ...| || .. | .. . | .|. .|  .  . |||| .|.|||.|. .|.
psvvledtlylGnakhatnekvlkdlkithivnvsqekkdafpksveYlqvkvedesdeqlssfleraakfladaidsGGrvlvhcvqGksrsssvtvaf

AMKEFGWPLEKAYNYVKQKRSITRPNAGFMRQLSEYEGI
 .|  || |..||.|.|..|||..|| ||..||...| .
LikskgwtlkeayeylkerrsivapnrGflkqlakfeel
subfamily_MKPLV_pd Subfamily MKPLV 309-446 4.7e-33 108.0 In-house 21-159 (164) alignment 
Range on Protein: 309-446
Range on HMM: 21-159/164.0
PSLIF-DHLYLGSEWNASNLEELQGSGVDYILNVTREIDNFFPGLFAYHNIRVYDEETTDLLAHWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAY
||... |.||||   .| | . |.   ...|.||..|  . ||  . | ...| || .. | .. . | .|. .|  .  . |||| .|.|||.|. .|.
psvvledtlylGnakhatnekvlkdlkithivnvsqekkdafpksveYlqvkvedesdeqlssfleraakfladaidsGGrvlvhcvqGksrsssvtvaf

AMKEFGWPLEKAYNYVKQKRSITRPNAGFMRQLSEYEGI
 .|  || |..||.|.|..|||..|| ||..||...| .
LikskgwtlkeayeylkerrsivapnrGflkqlakfeel
subfamily_Choan-DSP_MKP-1_pd Subfamily Choan-DSP_MKP-1 309-444 2.5e-30 98.9 In-house 7-144 (148) alignment 
Range on Protein: 309-444
Range on HMM: 7-144/148.0
PSLIFD-HLYLGSEWNASNLEELQGSGVDYILNVTREIDNFFPGLFA-YHNIRVYDEETTDLLAHWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIA
|| | | .|.|||   |..|| |.  ||  | | |.| || .      | .... |..  || | ....  |..||| .  ..|||..||||||.  ...
pseikdafLFlGskksaadlealkalgvtrivnatkerdnaldqrgieYlhvaldDkpkedlsaiFediiafvrkakdeGrrvLvhlqmGvsrssalall

YAMKEFGWPLEKAYNYVKQKRSITRPNAGFMRQLSEYE
. ..     |..|...||.||   .|| ||..|| |.|
wlidfkrvslkealalvkskrryvdpnlgfLkqLaele
0049260 (Phosphotyrosine protein) phosphatases II 309-447 3.9e-29 96.7 In-house 8-149 (152) alignment 
Range on Protein: 309-447
Range on HMM: 8-149/152.0
PSLIFDHLYLGSEWNASNLEELQGSGVDYILNVTREIDN---FFPGLFAYHNIRVYDEETTDLLAHWNEAYHFINK-AKRNHSKCLVHCKMGVSRSASTV
|  .  ....|... |.... |.  |...|...|.. ..   ... .. |... . |  . ||  .  ....||.| |.... ..||||. ||.|..  |
pfefiatqgpgpntladfwrmlkelgittivmltellelgklkceqyiqylhlpwpDhgvpdlsqlllflllfieklaldkggpvlVHCsaGvgRtgtlv

IAYAMKeFGWPLEKAYNYVKQKRSITRPNAGFMRQLSEYEGIL
.|| |. .|..||.|...|..||..  || |..|.| |.|..|
aaylml.lgvsleeavalvrekRpgavpnpgqlrflyefekll
subfamily_MSG5_pd Subfamily MSG5 309-449 2.5e-19 63.0 In-house 26-162 (165) alignment 
Range on Protein: 309-449
Range on HMM: 26-162/165.0
PSLIF-DHLYLGSEwnaSNLEELQgsGVDYILNVTREIDNFF---PGlFAYHNIRVydEETTDLLAHWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTV
| |.. ..||| ||    .|.||     | ..||..||...    |    |. |.   | .. .    ..  . |  |. .. | ||||. |.||||| .
pllvlpeklylyse...pklkell..sfdlvinvakeindlellvpa.vkyyhiew..ehdskivkdlsrltriihaatskrkkilvhcqcglsrsasli

IAYAMKEFGWPLEKAYNYVKQKRSITRPNAGFMRQLSEYEGILDA
.|| || ..  |..||. .| .     |. |.. || |.| .|..
vayimkyynlslrdaydklksvaddispsiglifqlmewevalsk
subfamily_DSP14_pd Subfamily DSP14 310-450 6.8e-38 124.1 In-house 8-147 (157) alignment 
Range on Protein: 310-450
Range on HMM: 8-147/157.0
SLIFDHLYLGsEWNASNLEELQGSGVDYILNVTREIDNFFPGLFAYHNIRVYDEETTDLLAHWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAM
| | ..|.|.    |.. |.|.  ..  |.|||.|. |     ... ...| |.....| .|..|..  |...|... |.||||..||||||| ..|| |
sqitpsLfls.gvaalskellkkkkitliinvtvelpntklkdiervkvpveDnpeaklakhfdevadkieevkkkggktlvhCvaGvSRSAslclaylm

KEFGWPLEKAYNYVKQKRSITRPNAGFMRQLSEYEGILDAS
|     |..||..||..|.| ||| || .|| .||  | ..
kyeklsLreayklvksaRpiirPNvGFwkqlidyEkklkgk
0036282 (Phosphotyrosine protein) phosphatases II 310-447 1.3e-24 82.3 In-house 13-169 (174) alignment 
Range on Protein: 310-447
Range on HMM: 13-169/174.0
SLIFDHLYLGSEWNAsNLEELQGSGVDYILNVTREI---------------DNFFPGLFAYHNIRVYDEETTDLLAhWNEAYHFINKAKRN--HSKCLVH
| | ..|..|.   | ..|.|.  |. .......|.               . . .  . |. . . | .. ||   . |.. |...|  .  . ..|||
syitprliagqgpla.fwemlkelgittvvmlleekelglykcinywpelredlerlgiqylylpwpDhgvpdlsi.llefvkfveealsedpggpvlVH

CKMGVSRSASTVIAYAMKEFGW-PLEKAYNYVKQKR---SITRPNAGFMRQLSEYEGIL
|..||.|..  |.|| |.  .. .|..|...|...|   .   .. ...|.| ..| .|
CsaGvgRtGtlvaaylmlrglleslvdaldlvrelRlqrpgmvqtpsQyrflyyfekll
0051082 (Phosphotyrosine protein) phosphatases II 310-443 5.2e-23 76.7 In-house 9-149 (151) alignment 
Range on Protein: 310-443
Range on HMM: 9-149/151.0
SLIFDHLYLGSEWNASNLEELQGSGVDYILNVTREI-----DNFFPG-LFAYHNIRVYDEETTDLLAHWNEAYHFINKAKRN-HSKCLVHCKMGVSRSAS
| . ..||...   | .||.|.  |...|.|.. |       ...|   . ...| . |  ...|  ..... .|.... .. . ..||||..|..|.. 
syvtgglyrsggpladflellkelgiktivnlrseeergycpeylpelgievlhipildwpdpglplsfdavleflellldkkngpvlvHCsaGkgRTGt

TVIAYAMKeFGWPLEKAYNYVKQKRS-ITRPNAGFMRQLSEY
 |..| |.  |..||.|......||  ...|| .|. || ..
lvalylml.lgvsleealeeyrlkrpgvvqpnqqflfqlfal
0037934 (Phosphotyrosine protein) phosphatases II 311-444 5e-25 83.9 In-house 41-238 (243) alignment 
Range on Protein: 311-444
Range on HMM: 41-238/243.0
LIFDHLYLGSE--------WNASNLEELQGSGVDYILNVTREI---------------------------------------------DNFFPGLFAYHN
 ....|....         . ||... |.  |...|...|...                                             |...   . || 
yvtprliatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqywpgevtygdftvtllseehlddytvrtlllenldlddltrlvihyhy

IRVYD----EETTDLLAHWNEAYHFINK-----AKRNHSKCLVHCKMGVSRSASTVIAYAMKEF-GWPLEKAYNYVKQKRSI-TRPNAGFMRQLSEYE
. . |    ....|||....|.. ||..     |  .....||||..||.|..  ..|| |..  |..||.|.......|.    .. ...|.| |..
lpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgRtGtliaaylmllllgvdleeavkllreqRpgkavqtpsqyrflyeal
subfamily_DSP19_pd Subfamily DSP19 312-445 3.3e-41 135.1 In-house 15-148 (152) alignment 
Range on Protein: 312-445
Range on HMM: 15-148/152.0
IFDHLYLGSEWNASNLEELQGSGVDYILNVTREIDNFFPGLFAYHNIRVYDEETTDLLAHWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKE
. ..|||||   |.. |.|.  .. .||||. ...|.||  | | .| ..|.. ||||....||  ||..|....   ||||. ||||||| |||| ||.
veprlylgsqdvaadkeilkekkitHilnvatgvpnvfpkdftylsieilDlpetdllsylkealdFieearskdgavlvHCnAGvSRsasvviaylmkk

FGWPLEKAYNYVKQKRSITRPNAGFMRQLSEYEG
    ||.|...|...|   .||.||..|| ||| 
eelsleealelvrearpcikPneGFikqLkeyea
subfamily_DSP12_pd Subfamily DSP12 312-447 1.7e-35 116.7 In-house 5-143 (155) alignment 
Range on Protein: 312-447
Range on HMM: 5-143/155.0
IFDHLYLGSEWNASNLEELQGSGVDYILNVTRE-ID--NFFPGLFAYHNIRVYDEETTDLLAHWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYA
| . ||||.  .. . | |.  ..  .| |..| ..  .  .|  .. .| ..||...|.| | .|| .||..|  .. . ||||..|||||...|||| 
ilpglylggleavqeeellkelkithvlsvikeelpehklkkgkvstkfiqilDepeediLshldeavdFieealeeegavlvHCqagvSRSvtiviAYl

MKEFGWPLEKAYNYVKQKRSITRPNAGFMRQLSEYEGIL
||. ...||||.. ||.|.. ..||.||..||  .| . 
mkkeklslekAlklvkekkpeiepNegFleQLklfekmg
0043147 (Phosphotyrosine protein) phosphatases II 312-448 1.7e-31 104.6 In-house 22-161 (172) alignment 
Range on Protein: 312-448
Range on HMM: 22-161/172.0
IFDHLYLGSEWNASNLEELQGSGVDYILNVTRE---IDNFFPGLFAYHNIRVYDEETTdLLAHWNEAYHFINK--AKRNHSKCLVHCKMGVSRSASTVIA
..........  |.... |.  |...|.|.|..    .....  . |. . ..|  .. ||... |...||..  |.... ..||||..||.|..  |.|
fiatqgplrntladfwrmlkelgithivnltellydpellerlgiqylylpwpDhgvp.llellleflefidellalspggpvlVHCsaGvgRtgtlvaa

YAMKeFGWPLEKAYNYVKQKRSITRPNAGFMRQLSEYEGILD
| |.  |..||.|...|..||..  .| ...|.| ..| .| 
ylml.lglsleeavalvrekRpgavqnpsqyrflyyfeklll
subfamily_DSP3_pd Subfamily DSP3 312-447 9.3e-29 94.2 In-house 14-157 (162) alignment 
Range on Protein: 312-447
Range on HMM: 14-157/162.0
IFDHLYLGSEWNASNLEELQGSGVDYILNVTRE----I---DNFFPGL-FAYHNIRVYDEETTDLLAHWNEAYHFINKAKRN-HSKCLVHCKMGVSRSAS
....||.| |  |.. ..|.  |. ..|| ..     .   ..|. .| . |. . | |  ..|| .....| .||..|  . ..| ||||..|||||| 
vypklyvgdeavakdkskLkklGithvlnaaegrfskvdtgaefykdleikylGlevdDvpefdlskyFetaakfidealsqkegkvlvhcvvGvsRsat

TVIAYAMKEFGWPLEKAYNYVKQKRSITrPNAGFMRQLSEYEGIL
 |.|| |      | .| . |..||.|. || ||..|| |..  |
lvlayLmirrkmtlveairtvrkkReil.PneGFlkqLaeldeel
subfamily_DSP15_pd Subfamily DSP15 312-446 9.5e-28 91.2 In-house 5-138 (151) alignment 
Range on Protein: 312-446
Range on HMM: 5-138/151.0
IFDHLYLGSEWNASNLEELQGSGVDYILNVTREIDNFFPGlFAYHNIRVYDEETTDLLAHWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKE
.   ||||   .... | |.   .  ||.|  .  ....  . |. |.. |   ..|  . .|. .|| |.. .  ..|||| .|||||.  |.|| |  
vlpglylgnfrdskdeelLkeknithilsvhdnakkllkd.ieYkciaasDtpsaklskffkesvefihkcRlkeenvlvhClaGvsRsvtlvvaYlmtv

FGWPLEKAYNYVKQKRSITRPNAGFMRQLSEYEGI
     ..| . .|..||.  ||.|| ||| |||  
telnwrdalevikaaRsvanPnfGfkrqlkeyekt
0042113 (Phosphotyrosine protein) phosphatases II 312-444 5.7e-21 70.5 In-house 50-239 (245) alignment 
Range on Protein: 312-444
Range on HMM: 50-239/245.0
IFDHLYLGSEWNASNLE----ELQGSGVDYILNVTREI----------------------------------------------DNFFPGLFAYHNIRVY
| .......   ....|     |.  |. .|...|.|                                               |..    . || . . 
itpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywplgesltygdftvtllseehlddytvrtlevtnlgddesrevihyhylpwp

DEETTDLLAHWNEAYHFINKAKR--NHSKCLVHCKMGVSRSASTVIAYAM-----KEFGWPLEKAYNYVKQKRSITRPNAGFMRQLSEYE
|  ..|||..  ....|..|| .  .. ..||||..||.|..  ..|| |     || |..||.|. .....|.  ... ...|.| |..
dhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylmleqlekelgvsleeavkelrsqRpgavqtpsqyrflyeal
0036941 (Phosphotyrosine protein) phosphatases II 312-444 5.6e-17 57.4 In-house 22-273 (297) alignment 
Range on Protein: 312-444
Range on HMM: 22-273/297.0
IFDHLYLGSEWNASNLEELQ----------------------------------------------------------GSGVDYILNVTREIDNFF----
....|.||| . |...| |.                                                            .|  |...|..... .    
llpllllgslsvallpenleknRykdilpydhtRVklddegsdYinAsyvdgydlkrkfIatqgPlpntvedFWrmvweqnvtvIvmltelvelgrekca

-------PGLFAYHNIRVYD------------------------------------EETTDLLAHWNEAYHFINKAKR------NHSKCLVHCKMGVSRS
       .. . |....|                                          ..  ....  .||.....      .... ||||..||.||
qywpleegesltygdftvtllsvevvllddytlrtlevtdtgngesrtvthfhytgwpdhgvpespaslldfielvrkvlkllpsggpvlVHCsaGvgRs

ASTVIAYAM--------KEFGWPLEKAYNYVKQKRSITRPNAGFMRQLSEYE
.. ..|. |        || |... .|.......|    .. ...|.| |..
gtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyeal
subfamily_STYX_pd Subfamily STYX 313-452 1.4e-23 76.8 In-house 16-162 (166) alignment 
Range on Protein: 313-452
Range on HMM: 16-162/166.0
FDHLYLGSE--WNASNLEELQGSGVDYILNVTREID-----NFFPGLFAYHNIRVYDEETTDLLAHWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVI
.  |.||       | || |.  |. .|. . ..|.       ||  | |  . | |. . ... .  .  .||... ..  | ||| . |.||||. ||
lpglflgpysaamksklevlkkhgithivcirqnieanlikpnfpdrfrylvldvadntveniirylptvkefiddslqkggkvlvhgnagisrsaalvi

AYAMKEFGWPLEKAYNYVKQKRSITRPNAGFMRQLSEYEGILDASKQ
|| |. .|    .|. ||...|    ||.||..|| ||| |  |  .
ayimetyglkyreafayvqerrfcinpnegfvsqlkeyeaiylaklt
0051429 (Phosphotyrosine protein) phosphatases II 313-443 2.1e-17 59.2 In-house 21-220 (272) alignment 
Range on Protein: 313-443
Range on HMM: 21-220/272.0
FDHLYLGSEW---NASNLEELQGSGVDYILNVTREI-------DNFFPGlFAYHNIRVYDEETTDLLAHW------------------------------
 . ||... .   .| ... |.  |...|.....|        | . || . |... ..|..... | ..                              
pgrlyrsggplpltaadfwrlkelgiktivdLrseeErgrlkcdrywpg.irylhlpilddsaptilygalrvtllseellldyilrellltlllsagea

------------------NEAYHFINKAKRnHSKCLVHCKMGVSRSASTVIAYAMKeFGWP--------------LEKAYNYVKQKRSITRPNAGFMRQL
                  ..  ....   . . ..||||. |..|..  | .. .   |..              ||.|.......|   ... .....|
revmhlhytdwpdhgvpqeallellellld.ggpvlvHCsaGkdRTGtvvalllll.lgvsletivddYlltnlyleeaveelraqrpgavqteeqylfl

SEY
 |.
yea
subfamily_STYXL1_pd Subfamily STYXL1 314-445 2e-22 73.1 In-house 17-151 (157) alignment 
Range on Protein: 314-445
Range on HMM: 17-151/157.0
DHLYLGSEWNASNLEELQGSGVDYILNVTREIDNFFPGLFA---YHNIRVYDEETTDLLAHWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMK
..|||| . .| | .  .   |   .||. . |... |.       .|.| ||. .||| . .|| .||.| |.. .  ||  . |.||||. .||| | 
gklylGnykqaqnpaikkdlkvkahvnvsmdadkliagvadvakllhiavedeneadllerlkeavqfiekhkkegevvlvfsnkGisrsaaviiaylmy

EFGWPLEKAYNYVKQKRSITRPNAGFMRQLSEYEG
.  . |.|||.|.|. ..  .|| .|. ||||.| 
skkitlkkaykylkkCkenvkPnrafveqlseWek
0040439 (Phosphotyrosine protein) phosphatases II 314-444 5.3e-22 74.1 In-house 34-242 (249) alignment 
Range on Protein: 314-444
Range on HMM: 34-242/249.0
DHLYLGSEWNASNLE------------------------ELQGSGVDYILNVTREIDN------------------------------------------
. |.|..  ||| ..                         |.  |. .|...|..  .                                          
pglflsdyinAsyidgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqywplggsleygdftvtllsvevkddytvrtleltn

-FFPGLFAYHNIRVYDEETTDLLAHWNEAYHFINKAKR------NHSKCLVHCKMGVSRSASTVIAYAM-----KEFGWPLEKAYNYVKQKRSITRPNAG
  ..  . .. |...|   ...  . ...  ||....       .....||||..||.|..  ..|| |     || |..|| |.......|.   .| .
lydgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtfiaaylmleqlekelgvdleeavkllrsqRpgavqnpe

FMRQLSEYE
..|.| |..
qyrflyeal
0038934 (Phosphotyrosine protein) phosphatases II 315-447 1.9e-19 65.5 In-house 37-176 (194) alignment 
Range on Protein: 315-447
Range on HMM: 37-176/194.0
HLYLGSEWNASNLEELQGSGVDYILNVTREIDNFFPGLFAYHNIRVYDEETTD--------LLAHWNEAYHFINKaKRNHSKCLVHCKMGVSRSASTVIA
 ||  | ..  .. .|.. .. .....| .   . | .|  ..|....  . |        .| .. .. ..... . .. ...||||.|..|..  |.|
elyrfspedlvrylkllnvklglvidltnteryYdpeefekagieylklpfpddgtvPsleillrfldlvdefln.edpggvvaVHCkaGlgRtGtlvaa

YAMKEFGWPLEKAYNYVKQKRSITRPNAGFMRQLSEYEGIL
| .. .|...|.|......||    || .....| .. . |
YLiyrlgmsaeeAialfrekRpgaipnqdyleallkrykel
DSPc Dual specificity phosphatase, catalytic domain 316-444 1.4e-36 120.3 Pfam-A 1-131 (133) alignment 
Range on Protein: 316-444
Range on HMM: 1-131/133.0
LYLGSEWNASnLEELQGSGVDYILNVTREIDN---FFPGLFAYHNIRVYDEETTDLLAHWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKEF
|||||. .|| |. |.  |.....|||.|..|   . .. . | .| | ||..|.. .. .||. ||.||.... |.||||..|.||||. .||| ||..
lylgskstas.lalleklgitlvinvtkevpnnnaikkseieylripvedetetkiskeleeavefiekaeqkgkkvlVHCqaGisRSatliiaYlmktk

GWPLEKAYNYVKQKRSITRPNAGFMRQLSEYE
...|..||..||..||. .|||||.||| |||
nlslneAyefvkerrskispnagflrqLleye
DSPc Dual specificity phosphatase, catalytic domain 316-444 1.4e-36 120.3 In-house 1-131 (133) alignment 
Range on Protein: 316-444
Range on HMM: 1-131/133.0
LYLGSEWNASnLEELQGSGVDYILNVTREIDN---FFPGLFAYHNIRVYDEETTDLLAHWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKEF
|||||. .|| |. |.  |.....|||.|..|   . .. . | .| | ||..|.. .. .||. ||.||.... |.||||..|.||||. .||| ||..
lylgskstas.lalleklgitlvinvtkevpnnnaikkseieylripvedetetkiskeleeavefiekaeqkgkkvlVHCqaGisRSatliiaYlmktk

GWPLEKAYNYVKQKRSITRPNAGFMRQLSEYE
...|..||..||..||. .|||||.||| |||
nlslneAyefvkerrskispnagflrqLleye
subfamily_Sponge-DSP-Subfam1_pd Subfamily Sponge-DSP-Subfam1 316-446 9.7e-16 51.2 In-house 6-140 (145) alignment 
Range on Protein: 316-446
Range on HMM: 6-140/145.0
LYLGSEWNASNLEELQGSGVDYILNVTRE----IDNFFPGLFAYHNIRVYDEETTDLLAHWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKE
|| ||  .|...  ||  |.  |.|..       ..     .    |   | |. ||  |..|   ||.| | . .  .|||  ||||| .  .|. || 
lyvgsalhandvptlqelgisrivnmaagslvasqelksesieillitaedlesydlsqhfdevtdfidkgkeegagvfvhcmagvsrsvtvsvaflmky

FGWPLEKAYNYVKQKRSITRPNAGFMRQLSEYEGI
 .  | .|   |. .|  . ||  |...| . |  
cnmtlseaarqvrsnrllaypnvtflknllnlekq
0045450 (Phosphotyrosine protein) phosphatases II 323-444 8.6e-21 70.4 In-house 88-300 (307) alignment 
Range on Protein: 323-444
Range on HMM: 88-300/307.0
NASNL--------------------------------EELQGSGVDYILNVTREIDN-------FF---------------------PGLFAYHNIRVYD
|||                                  . |.  || .|...|.....       ..                      . . .....| |
NAsyvrvpllllldgydlkrkfIatqgPlpetvedFwrmlweqgvtvivmltelvelgrekcaqywPdegeeltygnftvtllseehldgytvrtlevtd

E-----------------ETTDLLAHWNEAYHFINKAKR------NHSKCLVHCKMGVSRSASTVIAYAMKEFG--------WPLEKAYNYVKQKRSITR
                    ...  ...|. .||.....      .....||||..||.|... ..|| |.. .        ..|..|.......|.   
ldgtgesrtvthfhytgwpdhgvppsfeelldfieevrkaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgav

PNAGFMRQLSEYE
.| ...|.| |..
qnpeqyrflyeal
0039614 (Phosphotyrosine protein) phosphatases II 329-444 4.1e-18 61.3 In-house 120-285 (297) alignment 
Range on Protein: 329-444
Range on HMM: 120-285/297.0
ELQGSGVDYILNVTREIDN--------------------FFPGLFA----------------------YHNIRVYDEETTDLLAHWNEAYHFINKAKR--
 ..  || .|...|.....                     . . .                       .. .   |  . ..|..  |.......| .  
mvweqgvtvivmLtklvelgrkcaqywpeeggtygdftvtllkvehldgytvrtlevtnngesrtvthfqytgwpdhgvppslellleflelvrealael

-NHSKCLVHCKMGVSRSASTVIAYAM-----KEFGWPLEKAYNYVKQKRSITRPNAGFMRQLSEYE
 .. ..||||..||.|... ..|| |     || |. ...|.......|.  ... ...|.| ...
pkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavqtpsqyrflydal
0040438 (Phosphotyrosine protein) phosphatases II 330-443 8.6e-19 63.4 In-house 106-271 (317) alignment 
Range on Protein: 330-443
Range on HMM: 106-271/317.0
LQGSGVDYILNVTREIDN---------------------------FFPGLFAYHNIRVYDE----------------ETTDLLAHWNEAYHFINKAKRN-
..  || .|...|.. ..                           .  . . .....|.|                    ..  ....  .|....... 
vweqgvtvivmLteleelgrekcaqYwplgetltygdftvtllseeelagitlrtlevedlgdsesrtvthfhytgWpdhgvppspdllldfleavreal

---HSKCLVHCKMGVSRSASTVIAYAM-----KEFGWPLEKAYNYVKQKRSITRPNAGFMRQLSEY
   ....||||..||.|... ..|| |     || |. .|.|.......|.   .. ...|.| ..
edpggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrflyda
0043336 (Phosphotyrosine protein) phosphatases II 335-443 9.3e-15 50.3 In-house 158-272 (278) alignment 
Range on Protein: 335-443
Range on HMM: 158-272/278.0
VDYILNVTREIDNFFPGLFAYHNIRVYDEETT-DLLAHWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAM-----KEFGWPLEKAYNYVKQKRS
. . |.||.  |..      || . . | ..  .|  ...    .... . .... ||||. ||.|..  ...| .     || |..||.|.......| 
tvrtlevtnlgdgesrtvthyhylgwpdhgvpeslsllldflkavrealedsngpvlVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqRp

ITRPNAGFMRQLSEY
   ..  ..|.| |.
gavqtpsqyrflyea
0051299 (Phosphotyrosine protein) phosphatases II 337-432 1.3e-09 33.4 In-house 165-270 (288) alignment 
Range on Protein: 337-432
Range on HMM: 165-270/288.0
YILNVTRE----IDNFFPGLFAYHNIRVYDEETTDLLAHWNEAYHFINKA-KRNHSKCLVHCKMGVSRSASTVIAYAM-----KEFGWPLEKAYNYVKQK
. | ||.      |..      .| .   |  . | . .. . .....|| . ... ..|||. ||.|..  .... .     || |. ...|.......
rtlevtnldlldgdgesrtvthfhytnwpdhgvpdspellldflrlvrkalasgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlreq

RSITRP
|    .
Rpgmvq
0047943 (Phosphotyrosine protein) phosphatases II 355-440 1.8e-11 39.5 In-house 171-264 (273) alignment 
Range on Protein: 355-440
Range on HMM: 171-264/273.0
YHNIRVYDEETTDLLAHWNEAYHFINKAKR---NHSKCLVHCKMGVSRSASTVIAYAM-----KEFGWPLEKAYNYVKQKRSITRPNAGFMRQL
.|     |  . . |..  | .....|| .   .... .|||. ||.|... .... .     || |. ...|.......|    ..  ..|.|
fhytgwpdhgvppslesllefielvrkalealpsngpvvVHCsaGvgRtgtfialdllldqlekeggvdvleavkllrsqRpgmvqtpeqyrfl
subfamily_PTPMT1_pd Subfamily PTPMT1 356-445 1.3e-14 49.0 In-house 77-166 (171) alignment 
Range on Protein: 356-445
Range on HMM: 77-166/171.0
HNIRVYDEETTDLLAHWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQKRSITRPNAGFMRQLSEYEG
 .... |   .  |.. ... .||.| . . ..  |||| | .|||. |..| ||.  . .|.| ...|.||.|.| .   ...|.||| 
lqlatvDfteapdleklekgvefiekvaskgkrvYvHCkaGrgRsatlvacylmkkeklspeeAlkalkkkRkiirlakkqwkalqeyee
0046845 (Phosphotyrosine protein) phosphatases II 360-428 1.2e-08 30.2 In-house 175-254 (284) alignment 
Range on Protein: 360-428
Range on HMM: 175-254/284.0
VYDEETTDLLAHWNEAYHFINKAK---RNHSKCLVHCKMGVSRSASTVIAYAMKEF--------GWPLEKAYNYVKQKRS
  |  . . ...  | .......     .... .|||. ||.|..  .... ..|         |.....|.......| 
wpdhgvppspedlleflrlvrellenlpgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRp
0050432 (Phosphotyrosine protein) phosphatases II 367-429 6.7e-09 31.0 In-house 211-280 (308) alignment 
Range on Protein: 367-429
Range on HMM: 211-280/308.0
DLLAHWNEAYHFINKAKRN--HSKCLVHCKMGVSRSASTVIAYAM-----KEFGWPLEKAYNYVKQKRSI
.   ....  .|......   .....|||. ||.|..  .... .     || |. ...|.......|  
gvPpspeilldflelvrkslpggpivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkklReqRpg
0048567 (Phosphotyrosine protein) phosphatases II 375-438 3.2e-07 24.8 In-house 63-131 (157) alignment 
Range on Protein: 375-438
Range on HMM: 63-131/157.0
AYHFINKAKRNHSKCLVHCKMGV---SRSASTVIAYAMKEFGWPLEKAYNYVKQKR--SITRPNAGFMR
...|..  . .. .  ||||.|    .|.|  . .|... .|.. |.|...... |  |.  . |... 
lnkflkilelagkaiavhckaglkkrgrtatLigcYlilhlgftpeeaiaplrivrpgsvpfrdasyll