Gene UBLCP1 in Homo sapiens

Synonym: CPUB1, UBLCP1

Gene expression: GTEx, DEPOD

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold HAD
Superfamily HAD
Family FCP
Subfamily UBLCP1
Protein sequence
ID Type Fasta BLAST phosphatome Note
HsapP125_AA protein Get Run
HsapP125_AA_136-275 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
ubiquitin Ubiquitin family 18-76 4.4e-09 25.1 Pfam-A 11-66 (69) alignment 
Range on Protein: 18-76
Range on HMM: 11-66/69.0
TLSEDDTVLDLKQFLKTLTGVLPERQKLLglkVKGKPAENDVKLGALKLKPNTKIMMMG
.....|||..||. .   .|. ...|.|.    .||. |.| .|. ...... ..... 
evepsdtvselKekieekegipvdqqrLi...ysGkvLeDdrtlsdyniqdgstlhlvl
CPDc_SM00577 137-275 3.1e-20 64.7 In-house 2-143 (146) alignment 
Range on Protein: 137-275
Range on HMM: 2-143/146.0
KKLLVLDVDYTLFD------HRSCAET-----GVE-----LMRPYLHEFLTSAYEDYDIVIWSATNMKWIEakmkelgvstnanyKITFMLDSAAMITVH
||.|||| |.||        ..|..|.     ..|     |.|||..|||..|.. ...||......|...              .|  .||. ...  .
kkvLVlDLdetLvhsanmaepksfsevsptdslaetlvlvlkRPyvdeFLkkaaklfelvifTsaskkyad..............tildllDpkrllkyr

-TPRRGLIDVK-----P-LGVIWGkfsefySKKNTIMFDDIGRNFLMNPQNGLKIRPFMKAH
   |.    ||     . | ...       ........|.  ...|.||.| |||.|...|.
vlyRqdcrlvkgkllkddlsllkv......dlskvviiDnseestlvnpenalkikpyisal
subfamily_UBLCP1_pd Subfamily UBLCP1 138-275 4e-81 259.7 In-house 1-137 (138) alignment 
Range on Protein: 138-275
Range on HMM: 1-137/138.0
KLLVLDVDYTLFDHRSCAETGVELMRPYLHEFLTSAYEDYDIVIWSATNMKWIEAKMKELGVSTNANYKITFMLDSAAMITVHTPRRGLIDVKPLGVIWG
|||||||||||.|.||.||...||.||||.||||||||||||||||||.|||||.|.|||||..|.||||.|.|||.|||.|.||..|.|.||.|||||.
kllvldvdytlldfrsvaedalelkrpyleefltsayedydiviwsatsmkwievklkelGvadnpnykiafvldstamikvttpkygvievkalgviwk

KFSEFySKKNTIMFDDIGRNFLMNPQNGLKIRPFMKAH
|...| |.||||||||. |||||||.||||||||..|.
klekf.sskntimfddlrrnflmnpknGlkirpfkead
NIF NLI interacting factor-like phosphatase 138-300 2.5e-31 100.7 Pfam-A 1-158 (159) alignment 
Range on Protein: 138-300
Range on HMM: 1-158/159.0
KLLVLDVDYTLFDHRSCA-----------ETGVEL-MRPYLHEFLTSAYEDYDIVIWSATNMKWIEAKMKELGvstnanY-KITFmldsAAMITV-HT-P
|.||||.|.||.....             .| ... .||.|.|||... ..|..||..|......|. ...|       . |  |     ....  ..  
ktLVLDLDetLvhskekkdlkedgkkveektkasvkkRPgldeFLkelskayevviftasskeyaepvldkld......pkkklf....kkrlyresctl

RRGLIdVKPLGVIwgkfsefyS--KKNTIMFDDIGRNFLMNPQNGLKIRPFMKAHlnrDKDKELLKLTQYLKEIAKLDDF
|.| . || | ..        .   ......||  |.|...|.||..|.||....   |||.|||||...|....| ||.
rngky.vKdLsll........grdlsrvvivDdsprsfelqpdngipiepfygds...dkdtellkllpflealeksddv