Gene PXYLP1 in Homo sapiens

Synonym: ACPL2, HEL124, XYLP, UNQ370/PRO706, PXYLP1

Gene expression: GTEx, DEPOD

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold HP
Superfamily HP
Family HP2
Subfamily PXYLP1
Protein sequence
ID Type Fasta BLAST phosphatome Note
HsapP166_AA protein Get Run
HsapP166_AA_46-477 phosphatase_domain Get Run
Domains
Summary
100200300400MLFRNRFLLLLALAALLAFVSLSLQFFHLIPVSTPKNGMSSKSRKRIMPDPVTEPPVTDPVYEALLYCNIPSVAERSMEGHAPHHFKLVSVHVFIRHGDRYPLYVIPKTKRPEIDCTLVANRKPYHPKLEAFISHMSKGSGASFESPLNSLPLYPNHPLCEMGELTQTGVVQHLQNGQLLRDIYLKKHKLLPNDWSADQLYLETTGKSRTLQSGLALLYGFLPDFDWKKIYFRHQPSALFCSGSCYCPVRNQYLEKEQRRQYLLRLKNSQLEKTYGEMAKIVDVPTKQLRAANPIDSMLCHFCHNVSFPCTRNGCVDMEHFKVIKTHQIEDERERREKKLYFGYSLLGAHPILNQTIGRMQRATEGRKEELFALYSAHDVTLSPVLSALGLSEARFPRFAARLIFELWQDREKPSEHSVRILYNGVDVTFHTSFCQDHHKRSPKPMCPLENLVRFVKRDMFVALGGSGTNYYDACHREGFHP2Curated phosphatase domainHis_Phos_2Pfam Domainsubfamily_PXYLP1_pd(1)0048946(2)0049059(3)0047369(4)0049226(5)SubfamilyTransmembrane region
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
0047369 Phosphoglycerate mutase-like 47-476 6.9e-72 235.9 In-house 5-437 (438) alignment
0048946 Phosphoglycerate mutase-like 48-477 5.9e-76 249.1 In-house 4-411 (447) alignment
0049059 Phosphoglycerate mutase-like 52-458 3.7e-75 246.4 In-house 9-424 (435) alignment
subfamily_PXYLP1_pd Subfamily PXYLP1 66-478 4.6e-208 682.5 In-house 2-419 (419) alignment
subfamily_HP2-Group1_pd Subfamily HP2-Group1 81-224 2.2e-14 44.6 In-house 14-153 (422) alignment
0048439 Phosphoglycerate mutase-like 82-457 1.3e-64 211.9 In-house 3-387 (391) alignment
0046349 Phosphoglycerate mutase-like 83-461 1.4e-63 208.5 In-house 3-404 (409) alignment
subfamily_ACP2_pd Subfamily ACP2 83-458 1.5e-49 161.4 In-house 4-346 (361) alignment
subfamily_ACP6_pd Subfamily ACP6 86-430 1.3e-32 104.9 In-house 2-341 (376) alignment
0049226 Phosphoglycerate mutase-like 87-475 1e-67 221.8 In-house 2-340 (342) alignment
0053031 Phosphoglycerate mutase-like 87-459 7.9e-67 218.9 In-house 2-331 (342) alignment
His_Phos_2 Histidine phosphatase superfamily (branch 2) 87-424 3.1e-46 150.8 Pfam-A 1-347 (347) alignment
His_Phos_2 Histidine phosphatase superfamily (branch 2) 87-424 3.1e-46 150.8 In-house 1-347 (347) alignment
subfamily_HP2-Group1_pd Subfamily HP2-Group1 295-438 9.9e-16 49.1 In-house 252-393 (422) alignment