Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
---|---|---|---|---|---|---|---|---|---|
0048567 | (Phosphotyrosine protein) phosphatases II | 222-401 | 4.7e-40 | 131.3 | In-house | 3-156 (157) | alignment | ||
Range on Protein: 222-401
Range on HMM: 3-156/157.0
QIDNACVIVPDRLYFATVRQLPPSTPEAFFFTVDSEFKYEafvsrpathaprnsapspqpfgltmcGFCADFGPFNLSTSVRFCRKLWQFLEQPQHKDQR
.. ....|.|||||||....|| |...|..|..| .. || |..||||.||.. .||..||..||.........
engdlieiipdrlyfallprlpkslynalyFsiddglvye..........................dfffdfGPlnlailyrFilklnkflkilelagka
IYFCTGTDMQVRSNAAALIGLFAVWCLNMTDEQAIACLDTAKPPFAPFRDASYAPVLYKLHVRYVISGAYQALLNGFIDV
|.... .... |...| |||......|..| |.|||.| . |.. |||||||.. ||.|.. |..| ..|| .||.|.
iavhckaglkkrgrtatLigcYlilhlgftpeeaiaplrivrpgsvpfrdasyllslynltlldvlyGllkAlelgfldl
|
|||||||||
subfamily_CDC14_pd | Subfamily CDC14 | 224-574 | 2.2e-158 | 521.3 | In-house | 1-326 (328) | alignment | ||
Range on Protein: 224-574
Range on HMM: 1-326/328.0
DNACVIVPDRLYFATVRQLPPSTPEAFFFTVDSEFKYEafvsrpathaprnsapspqpfgltmcGFCADFGPFNLSTSVRFCRKLWQFLEQPQHKDQRIY
|||.....|||||||.|. | ||.|...|.||.|.||| |.|||||.||....|.|.||...|.........|.
dnalelledrlyfatlrkkPkstselhyfsvddelkye..........................nfyadfGPlnlavlyrycvklnkkLkseekaskkiv
FCTGTDMQVRSNAAALIGLFAVWCLNMTDEQAIACLDTAK-PPFAPFRDASYAPVLYKLHVRYVISGAYQALLNGFIDVHTFDLDTYDHFERVENGDFTT
..|..|.. |.|||.|||..||..|..|.|.|...|..|. |||.|||||||... |||....|..|...|| .||.|...|||..|...||||||||..
lytsadskkranaalligayaviylkktaeeayraleaaetppfvpfrdasygsasykltlldvlkgvekalqkgfldledfdleeYekyervenGDfnw
IIPNKFIALAGPHNTRHVDDGYTHLAPENLFEPFRRLGVTDIVRLNKKMYDRTKFTQAGFAHHDLFFIDGTCPPPAILESFLEITEKCTGTAVVHCKAGL
|.|.||.|||||||.....|||.. |||.|.| ||. .||..||||||.||..|||.|||.|.|||||||..|. ||...||||.||..|...|||||||
ivPdkflalagPhnkskledgyplhaPeklleyfrknnvttvvrLnkklYdakkftdaGfdhkDlffiDGstPsdaivkkfleiaekaeGaiavhCkaGL
GRTGSLIGCYMMKHYRFNAPETIAWLRIARPGSVIGPQQTYLVNHQADMWLA
||||.||.||.||||||.|.|.||||||.||||||||||..|...||..||
GrtGtLiacylmkhyrftaaeaiawlricrPGsvigpqqkfleekqaalwle
|
|||||||||
DSPn | Dual specificity protein phosphatase, N-terminal half | 228-264 | 7.4e-10 | 29.7 | Pfam-A | 2-38 (141) | alignment | ||
Range on Protein: 228-264
Range on HMM: 2-38/141.0
VIVPDRLYFATVRQLPPSTPEAFFFTVDSEFKYEAFV
...|||||..... | .|.. ..|..|.|..|| |.
eliedrLyfvslkkkpkktenthyfsiDeelvYepfy
|
|||||||||
DSPn | Dual specificity protein phosphatase, N-terminal half | 288-393 | 1e-30 | 97.3 | Pfam-A | 36-141 (141) | alignment | ||
Range on Protein: 288-393
Range on HMM: 36-141/141.0
GFCADFGPFNLSTSVRFCRKLWQFLEQPQHKDQRIYFCTGTDMQVRSNAAALIGLFAVWCLNMTDEQAIACLDTAKPPFAPFRDASYAPVLYKLHVRYVI
.|.||||| ||. .|||.|| . |.....|...|...|..|.. |.||| ||| .|| .|... |.|.. | ...|.. ||||||| . |.|.. ..
pfyadFGPlnlaqiyrfcvklnkkLkeaelkkkkivlytsldekkranaalLigaYavivlklspeealkplesvepsllpFrDAsygestyeltildcl
SGAYQA
.| ..|
kglekA
|
|||||||||
0050432 | (Phosphotyrosine protein) phosphatases II | 361-567 | 1e-32 | 109.1 | In-house | 6-293 (308) | alignment | ||
Range on Protein: 361-567
Range on HMM: 6-293/308.0
TAKPPFAPFRDASYAPVLYKLHVRYVISGAYQALLNGFID------VHTFDLDTYDHFERVENGDFTT-------------------------------I
| ... .|||.|. .. .||.| .. ..|| .|... ....| .|......||.|. .
dallelllfrdtsilvsslklsvldllkllekaldlglleeefeellsvkplleysvallpenkdkNrykdilpydhsRVkldegsdYInAsyvdgyssk
IPNKFIALAGPHntrhvddgytHLAPENLFEPFRRLGVTDIVRLNKKMYDR-TKFTQ-------AGFAHHDLFFI-------------------------
.|.|||| ||. . |. . . .|. ||.|.| ... |. | |. ... |..
lprkfIatqgPl..........pntvedFwrmvweqnvrvIvmLtklvengrekcaqYwplelgggsleygkftvtllseevlddytvrtleltnlgdge
-------------DGTCPP-PAILESFLEITEKC--TGTAVVHCKAGLGRTGSLIGCYMM-----KHYRFNAPETIAWLRIARPGSVIGPQQTYLVNH
|. .|| |.|| .|||. .|. |. ||||.||.|||| .| .... |.......|....|| |||.|..|.| ... .
srtvthfhytnWpdhgvPpspeilldflelvrkslpggpivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkklReqRpgmvqtpeqylflyr
|
|||||||||
0045450 | (Phosphotyrosine protein) phosphatases II | 364-565 | 1.7e-30 | 102.3 | In-house | 3-296 (307) | alignment | ||
Range on Protein: 364-565
Range on HMM: 3-296/307.0
PPFAPFRDASYAPVLYKLHVRYVISGAYQALLnGFIDVHTFDLDTYDHFERVENGDFTTI----------------------------------------
.|. .|.|| . |..| .. ..| ... ...|..|.|..|......||.|. .
lplslfidalkllllvllllldfltgllkefe.kllsvtvfllgeysiallpenkdknrykdilpydhtRVklssldgsledsdYiNAsyvrvpllllld
---IPNKFIALAGPHNTrhvddgythlAPENLFEPFRRLGVTDIVRLNKKMYDRTK------------------------------------------FT
...|||| ||.. .|. .. ....||| ||.|.. ... . .|
gydlkrkfIatqgPlpe..........tvedFwrmlweqgvtvivmltelvelgrekcaqywPdegeeltygnftvtllseehldgytvrtlevtdldgt
QAGFAHHDLFF---IDGTCPP-PAILESFLEITEK------CTGTAVVHCKAGLGRTGSLIGCYMMKHYR--------FNAPETIAWLRIARPGSVIGPQ
. .. .. ... |...|| ...| .|.|. .| . | .|||.||.||||..|..|.|.... ....|....|| |||.| |.
gesrtvthfhytgwpdhgvppsfeelldfieevrkaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpe
QTYLV
| . .
qyrfl
|
|||||||||
0039614 | (Phosphotyrosine protein) phosphatases II | 368-566 | 4e-30 | 100.7 | In-house | 3-282 (297) | alignment | ||
Range on Protein: 368-566
Range on HMM: 3-282/297.0
PFRDASYAPVLYKLHVRYVISGAYQALLNGFIDVHTFDL----DTYDHFERVENGDFTTII------------------------------------PNK
|.|||.. .....|.| .. . ..|. ..... . ..| . | .....||.|. .. ..|
plrdallesipiplsvldlllllekansktllllefeellslkpdysiallpenkdknrykdilpydhsrvklkpedgvdldsdYinAsyvdgydlltrk
FIALAGPHNTrhvddgythlAPENLFEPFRRLGVTDIVRLNKKMYDRTKF----------------------TQAGFA-----------------HHDLF
||| ||.. .|. .. ....||| ||.|.| ... |. . .|. .. .
fIatqgPlpe..........tvedFwrmvweqgvtvivmLtklvelgrkcaqywpeeggtygdftvtllkvehldgytvrtlevtnngesrtvthfqytg
FIDGTCPP-PAILESFLEITEK------CTGTAVVHCKAGLGRTGSLIGCYMM-----KHYRFNAPETIAWLRIARPGSVIGPQQTYLVN
. |...|| ...| .|||. .. | .|||.||.||||..|..|.| |.......|....|| .|||.| |.| . .
wpdhgvppslellleflelvrealaelpkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavqtpsqyrfly
|
|||||||||
0049772 | (Phosphotyrosine protein) phosphatases II | 379-561 | 2.3e-32 | 108.4 | In-house | 79-268 (314) | alignment | ||
Range on Protein: 379-561
Range on HMM: 79-268/314.0
YKLHVRYVIsGAYQALLNGFIDVHTFDLDTYDHFERVENGDFTTIIPNK---------------------FIALAGPHntrhvddgythlapenlfepfR
| .. | . | ....| ..... |.....|..||. .... . .. | |..
yvdgflkfI.atqgpleitvvdfreepvlyyngwrmvlrgdlnvrdivmsrdevladelsrLdaAlgKtpllildgng.....................n
RLGVTDIVRLNKKMYDRTKFTQAGFAHHDLFFIDGTCPPPAILESFLEITEK--CTGTAVVHCKAGLGRTGS-LIGCYMMKHYRFNAPETIAWLRIARP-
. . |. |.. .||. .|...|. .... . ||..|.......|||. |. | .|||||| ||||. .. .|.||...... |.....| .||
eptaadlellkeelydpelferlgikylripvpDgsaplledfdeflefieeadkggpvlvHCkaGkgRtgtfvvaaylmkllgvsleealedvrlkRpi
----GSVIGPQQ
|.. ..|
npnpgfieqleq
|
|||||||||
0040438 | (Phosphotyrosine protein) phosphatases II | 381-567 | 1.8e-33 | 111.6 | In-house | 7-270 (317) | alignment | ||
Range on Protein: 381-567
Range on HMM: 7-270/317.0
LHVRYVISGAYQALLNGFIDVHTFDLDTYDHFERVENGDFTTII----------------------------------PNKFIALAGPHNTrhvddgyth
|.. ... . .|||..|.|. ...||||...|..||.|. . ..|||| ||..
lalldllksdftalleefedllslkldtysvaelpenkdknrypdilpydhsRVkLsplggdldsdYInAsyvdgpnlkrkfIatqgPlpn.........
lAPENLFEPFRRLGVTDIVRLNKKMYD------------------------RTKFTQAGFAHHDLFF-------------------IDGTCPP-PAILES
|. .. . ..||| ||.|.. ... . .. ||. .. | . |...|| | .| .
.tvedFwrmvweqgvtvivmLteleelgrekcaqYwplgetltygdftvtllseeelagitlrtlevedlgdsesrtvthfhytgWpdhgvppspdllld
FLEITEKC----TGTAVVHCKAGLGRTGSLIGCYMM-----KHYRFNAPETIAWLRIARPGSVIGPQQTYLVNH
|||. ... | .|||.||.||||..|..|.| |.......|....|| .|||.| |.| . .
fleavrealedpggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrflyd
|
|||||||||
0043336 | (Phosphotyrosine protein) phosphatases II | 381-565 | 1.5e-30 | 102.0 | In-house | 9-269 (278) | alignment | ||
Range on Protein: 381-565
Range on HMM: 9-269/278.0
LHVRYVISGAYQALLNGFIDVHTFDLDTYDHFERVENGDFTTII----------------------------------PNKFIALAGPHNTrhvddgyth
..... . ...||..| ....|.||||......||.|. . |.|||| ||..
kallelllnlktllllefeellsfkldtysiallpenkdknrykdilpydhsrvklsllggdldsdYinAsyvdgynvprkfiatqgPlpe.........
lAPENLFEPFRRLGVTDIVRLNKKM--------------------------------------------YDRTKFTQAGFAHHDLFfiDGTCP-PPAILE
.|. .. .. |||| ||.|.. . .| ..| .. ... |...| ....|
.tvedFwrmvwelgvttivmLtelvelgrvkcaqYwpggsltygdftvtllkeehlddytvrtlevtnlgdgesrtvthyhylgwp..dhgvpeslslll
SFLEITEK----CTGTAVVHCKAGLGRTGSLIGCYMM-----KHYRFNAPETIAWLRIARPGSVIGPQQTYLV
.||.. . . | .|||.||.|||| .|..|.. |.......|....|| |||.| |.| . .
dflkavrealedsngpvlVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqRpgavqtpsqyrfl
|
|||||||||
0047943 | (Phosphotyrosine protein) phosphatases II | 391-566 | 4.6e-24 | 80.8 | In-house | 18-265 (273) | alignment | ||
Range on Protein: 391-566
Range on HMM: 18-265/273.0
YQALLNGFIdvhtfdLDTYDHFERVENGDFTTI------------------------------IPNKFIALAGPHNTRhvddgythlaPENLFEPFRRLG
...||. .. | || .....||.|. . ...|||| || . |. . . .
felllslkp......lltysvallpenkdknrykdilpydhsrvklgdggsdyinAsyvdgynlkrkfiatqgPlpnt..........vedfwrmvweqn
VTDIVRLNKKMYD----------------------------------------------RTKFTQAGFAHHDLFFIDGTCP-PPAILESFLEITEK----
|. ||.|.. ... |. . .| . . | .| ...| .|.|. .|
vrviVmLtelvelgrekcaqYwpleggelsltygkftvtllseetkddytvrtleltnlgtgesrtvthfhytgwpdhgvppslesllefielvrkalea
--CTGTAVVHCKAGLGRTGSLIGCYMM-----KHYRFNAPETIAWLRIARPGSVIGPQQTYLVN
|. ||||.||.||||..| .... |.......|....|| |||.|. |.| ...
lpsngpvvVHCsaGvgRtgtfialdllldqlekeggvdvleavkllrsqRpgmvqtpeqyrfly
|
|||||||||
0045098 | (Phosphotyrosine protein) phosphatases II | 393-571 | 4.6e-30 | 100.4 | In-house | 9-271 (278) | alignment | ||
Range on Protein: 393-571
Range on HMM: 9-271/278.0
ALLNGFIDVHTFDLDTYDHFERVENGDFT----------------------T-IiPNKFIALAGPHNtrhvddgythLAPENLFEPFRRLGVTDIVRLNK
.|| .. ..... ... .. ...|.|. . |.|||| .||.. .. .. .. ||.| ||.|..
lllefefllllgipseitpalylgnldknRykdilpydhsrVkdYINAsyidgy.pkkfIatqgPlp..........stvadfwrmlwelgitvivmlte
KMYDR----------------------------------------------TKFTQAGFAHHDL-FFIDGTCPPPAILESFLEITE--------------
... . ....|. |... .. |...|. || ||||..|
lvelgrekcaqywpeggsltygdftvtllseevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslll
------KCTGTAVVHCKAGLGRTGSLIGCYMMKHY---RFNAPETIAWLRIARPG-SV-IGPQQTYLVNHQADM
|. .|||.||.|||| |...|.|... .....|....|| ||| .| . |. .| ....
sslllldsggpvlVHCsaGvgRtGtlvaaylmlelleggvdlleavkelrsqRpglavqnleqyrflyefllel
|
|||||||||
0044763 | (Phosphotyrosine protein) phosphatases II | 402-571 | 9.3e-31 | 102.2 | In-house | 5-170 (178) | alignment | ||
Range on Protein: 402-571
Range on HMM: 5-170/178.0
HTFDLDTYDHFERVENGDFTTIIPNKFIALAGPhntrhvddgythlapENLFEPFRRLGVTDIVRLNKKMY------DRTKFTQAGFAHHDLFFIDGTCP
. ..|... ..||... ... |.|. ... ..| .. .| ...||.| ||.|.. .. |. ...||. .. . . |...|
trvllsnleglersdyinaseilpglylgslpp...............addlellkelgithivnlteelelgflkcdpywpeeagiqylhipipDhgvp
P-PAILESFLEITE----KCTGTAVVHCKAGLGRTGSLIGCYMMKHYRFNAPETIAWLRIARPGSVIGPQQTYLVNHQADM
. ..... |.|. | .. |. .|||.||.||.|.|. .|.||.......| |...| .||.. |. .| . .
dllehflefvefieealdekggpvlVHCsaGvgRsgtlvaaylmkklglsleeaielvrerRpivpnpgqlrqLyefelrl
|
|||||||||
0041856 | (Phosphotyrosine protein) phosphatases II | 405-568 | 3.6e-36 | 119.8 | In-house | 3-166 (182) | alignment | ||
Range on Protein: 405-568
Range on HMM: 3-166/182.0
DLDTYDHFERVENGDFTTIIPNKFIALAGPHNTRHVDDGYTHLAPENLFEPFRRLGVTDIVRLNKKMYDRTKFTQAGFAHHDLFFIDGTCPPPAILESFL
|.. | .. ..... . . | ..... . |... .. |.. ... .. ...||.| ||.|. .|. ......|. ...|.. |...|.. .| .|.
dknrysdilpydhsrdldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlteelywpellerlgiqylylpwpDhgvpdldelldfi
EITEKCTGTAVVHCKAGLGRTGSLIGCYMMKHYRFNAPETIAWLRIARPGSVIGPQQTYLVNHQ
|. .. |. .|||.||.||||.|...|.||.......|.....| .|||.|| |.| ... .
eevleeggpvlVHCsaGvgRtgtlvaaylmkklgvsleeavklvrsrRpgmvitpnqyfflqla
|
|||||||||
0051429 | (Phosphotyrosine protein) phosphatases II | 405-568 | 1.2e-17 | 59.9 | In-house | 2-220 (272) | alignment | ||
Range on Protein: 405-568
Range on HMM: 2-220/272.0
DLDTYDHFERVENGdFTTIIPNKFIALAGPHNTRHVDdgythlapenlFEPFRRLGVTDIVRLNKKM---YDRTKFTQAGFAHHDLFFIDGTCPPP----
.|..| .. | . ...|..... .||.. . | |. ...||.. || | . . .. . . .|. .. | ..| . |..
plsgyiNardvggy.grvvkpgrlyrsggplpltaad...........fwrlkelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilyga
------------------------------------------------AILESFLEITEKcTGTAVVHCKAGLGRTGSLIGCYMMKhYRFN---------
| ..||. . | .|||.|| .||| .. .... ....
lrvtllseellldyilrellltlllsagearevmhlhytdwpdhgvpqeallellellld.ggpvlvHCsaGkdRTGtvvalllll.lgvsletivddYl
-----APETIAWLRIARPGSVIGPQQTYLVNHQ
. |....|| .|||.| ..| . . .
ltnlyleeaveelraqrpgavqteeqylflyea
|
|||||||||
0038934 | (Phosphotyrosine protein) phosphatases II | 409-562 | 1.3e-35 | 118.2 | In-house | 6-166 (194) | alignment | ||
Range on Protein: 409-562
Range on HMM: 6-166/194.0
YDHFERVENgdfttIIPNKFIALAGPHNTR--HVDDGYTHLAPENLFEPFRRL--GVTDIVRLN--KKMYDRTKFTQAGFAHHDLFFID-GTCPPPAILE
. ..|||.. ||...|||...|.. . .. ... ...||.|.. .. | ... ...|. ...||...|..||. ...|.|.| ||.|. .||
wlkyervgd.....iitgrfiafkvPlsgsldkyieelyrfspedlvrylkllnvklglvidltnteryYdpeefekagieylklpfpddgtvPsleill
SFLEIT-----EKCTGTAVVHCKAGLGRTGSLIGCYMMKHYRFNAPETIAWLRIARPGSVIGPQQT
.||.. |. |. .||||||||||| |...|........| | ||..|..|||... ...
rfldlvdeflnedpggvvaVHCkaGlgRtGtlvaaYLiyrlgmsaeeAialfrekRpgaipnqdyl
|
|||||||||
PTEN_1 | 409-570 | 6.3e-25 | 83.1 | In-house | 14-190 (196) | alignment | |||
Range on Protein: 409-570
Range on HMM: 14-190/196.0
YDHFERVENGDFTTIIPNKFIALAGP-HNtRHVDDGYTHLAPEN--LFEPFRRLGVTDIVRLNK------KMYDRTKFTQAGFAHHDLFFIDGTCPPPAI
... | .... .|. | .. | . | . .. .. | .... ... . |.| .|.|. . || ..| . |. .... . | . |. .
alptelldltyitsriiamgkapsrpllq.eideglyrgslkdvaadldnlkedgitlvvnlseeeelsgrsydleeffksgveylhfpieDhgapslse
LESFLEITEKC------TGTAVVHCKAGLGRTGSLIGCYMMKHYRFNAPETIAWLRIAR-PGSVIGPQQTYLVNHQAD
| ... . . ....|||||||||.| .. .|.|......| |.....|..| ||.. |.| |.. .|.
lfdicksfiewllsdpngnvVlVHCkaGlgRsGtvvaayLmykgkltadeAlelvrekRppgapnspsqerlleyfae
|
|||||||||
0042113 | (Phosphotyrosine protein) phosphatases II | 410-565 | 7.3e-29 | 96.3 | In-house | 2-235 (245) | alignment | ||
Range on Protein: 410-565
Range on HMM: 2-235/245.0
DHFERVENGDFTTI----------------------------------IPNKFIALAGPHNTrhvddgythlAPENLFEPFRRLGVTDIVRLNKKMYD--
......||.|. . |..|||| .||.. .|. .. ...||.| ||.|.. ...
svallpenkdknrysdilpydhtrvklspdggdldsdyinasyvdgyritpkfiatqgPlpe..........tvedfwrmlwelgittivmLteeeelgr
-----------------------------------------RTKFTQAGFAHHDLFFIDGTCPP-PAILESFLEITEK-----CTGTAVVHCKAGLGRTG
...... .. .| | . |...|. ...|..|||. .| |. .|||.||.||||
vkcaqywplgesltygdftvtllseehlddytvrtlevtnlgddesrevihyhylpwpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtG
SLIGCYMM-----KHYRFNAPETIAWLRIARPGSVIGPQQTYLV
.|..|.| |.......|....|| |||.| |.| . .
tfiaaylmleqlekelgvsleeavkelrsqRpgavqtpsqyrfl
|
|||||||||
0040439 | (Phosphotyrosine protein) phosphatases II | 411-565 | 1.4e-27 | 92.3 | In-house | 5-238 (249) | alignment | ||
Range on Protein: 411-565
Range on HMM: 5-238/249.0
HFERVENGDFTTI----------------------------------IPNKFIALAGPHNTrhvddgythlAPENLFEPFRRLGVTDIVRLNKKM-----
.....||.| . |...||| || . . |. .. ...||.| ||.|.. .
vallpenkdknrypdilpydhsrvklsilpglflsdyinAsyidgyyikrrfiatqgPlpe..........tvedfwrmlwelgitvivmLtslvelgre
----------------------------------------YDRTKFTQAGFAHHDLFfIDGTCPPPAILESFLEITEK------CTGTAVVHCKAGLGRT
|| ...| .. ..|. .|..| ...| .|.|. .| . | .|||.||.|||
kcaqywplggsleygdftvtllsvevkddytvrtleltnlydgesrtvlhiqytdwp.dhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRt
GSLIGCYMM-----KHYRFNAPETIAWLRIARPGSVIGPQQTYLV
| .|..|.| |.......|....|| .|||.| |.| . .
GtfiaaylmleqlekelgvdleeavkllrsqRpgavqnpeqyrfl
|
|||||||||
0043147 | (Phosphotyrosine protein) phosphatases II | 413-567 | 1.7e-32 | 107.9 | In-house | 8-155 (172) | alignment | ||
Range on Protein: 413-567
Range on HMM: 8-155/172.0
ERVENGDFTTiIPNKFIALAGPhntrhvddgyTHLAPENLFEPFRRLGVTDIVRLNKKMYDRTKFTQAGFAHHDLFFIDGTCPPPAILESFLEITEK---
..... |.. ||..||| || . . .. ...||.| ||.|.. .||...... |. .. | . |...|....|..|||. ..
inasyldlyy.ipdrfiatqgp..........lrntladfwrmlkelgithivnltellydpellerlgiqylylpwpDhgvpllellleflefidella
--CTGTAVVHCKAGLGRTGSLIGCYMMKhYRFNAPETIAWLRIARPGSVIGPQQTYLVNH
|. .|||.||.|||| |. .|.|. ..... |..|..| .|||.| |.| ... .
lspggpvlVHCsaGvgRtgtlvaaylml.lglsleeavalvrekRpgavqnpsqyrflyy
|
|||||||||
0037934 | (Phosphotyrosine protein) phosphatases II | 414-566 | 6.4e-30 | 99.9 | In-house | 33-235 (243) | alignment | ||
Range on Protein: 414-566
Range on HMM: 33-235/243.0
RVENGDFTTIIPNkFIALAGPHNTRHVDdgythlAPENLFEPFRRLGVTDIVRLNKKM------------------------------------------
|...... |. .|| ||.. . | .... .. . .||.| || |.. .
dyinanliyvtpr.liatqgPlpetved......dlasfwrmlwelgitvivmltelvElgrekcaqywpgevtygdftvtllseehlddytvrtlllen
YDRTKFTQAGFAHHDLFFIDGTCPP-PAILESFLEITE------------KCTGTAVVHCKAGLGRTGSLIGCYMMKHY-RFNAPETIAWLRIARPG-SV
.| ...|. .. .| | . |...|. |..| .||... . |. .|||.||.|||| || .|.|... .... |....|| ||| .|
ldlddltrlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgRtGtliaaylmllllgvdleeavkllreqRpgkav
IGPQQTYLVN
|.| . .
qtpsqyrfly
|
|||||||||
0048567 | (Phosphotyrosine protein) phosphatases II | 415-572 | 8.4e-35 | 114.3 | In-house | 2-138 (157) | alignment | ||
Range on Protein: 415-572
Range on HMM: 2-138/157.0
VENGDFTTIIPNKFIALAGPHNTRhvddgythlapenlfepfrrlgvtdivrlnkKMYDRTKF-TQAGFAHHDLFFIDGtcPPP--------AILESFLE
.||||...|||..... ..|. .. ..|.. | ...|. ..|.|| .| |.. .|..||.
kengdlieiipdrlyfallprlpk...............................slynalyFsiddglvyedfffdfG..PlnlailyrFilklnkflk
ITEKCTGTAVVHCKAGL---GRTGSLIGCYMMKHYRFNAPETIAWLRIARPGSVIGPQQTYLVNHQADMW
|.|.. .. .||||||| |||. |||||...|..|.. |.||.|||.|||||......||. .. ..
ilelagkaiavhckaglkkrgrtatLigcYlilhlgftpeeaiaplrivrpgsvpfrdasyllslynltl
|
|||||||||
0051082 | (Phosphotyrosine protein) phosphatases II | 419-567 | 2e-26 | 87.8 | In-house | 7-147 (151) | alignment | ||
Range on Protein: 419-567
Range on HMM: 7-147/151.0
DFTTIIPNkFIALAGPHNtrhvddgythlapeNLFEPFRRLGVTDIVRLNKKM---YDRTKFTQAGFAHHDLFFIDGTCPPP----AILESFLEITEKC-
.|. . .. ... .||.. .| ...||.. || |.... |. ....|. .... ..| . |. ... .|||. ...
nfsyvtgg.lyrsggpla..............dflellkelgiktivnlrseeergycpeylpelgievlhipildwpdpglplsfdavleflellldkk
TGTAVVHCKAGLGRTGSLIGCYMMKhYRFNAPETIAWLRIARPGSVIGPQQTYLVNH
| .|||.||.|||| |...|.|. ..... |.....|. |||.|. .|| ... .
ngpvlvHCsaGkgRTGtlvalylml.lgvsleealeeyrlkrpgvvqpnqqflfqlf
|
|||||||||
0036282 | (Phosphotyrosine protein) phosphatases II | 422-565 | 1.5e-28 | 95.1 | In-house | 13-162 (174) | alignment | ||
Range on Protein: 422-565
Range on HMM: 13-162/174.0
TIIPNKFIALAGPHNtrhvddgythlapenLFEPFRRLGVTDIVRLNKKMYDR------------TKFTQAGFAHHDLFFIDGTCPPPAILESFLEITEK
..|....|| .||.. .| ...||.|..|.|.. ... . ... |. ...| . |...|. .||..|... |.
syitprliagqgpla...............fwemlkelgittvvmlleekelglykcinywpelredlerlgiqylylpwpDhgvpdlsillefvkfvee
C-----TGTAVVHCKAGLGRTGSLIGCYMMKHYRF-NAPETIAWLRIAR---PGSVIGPQQTYLV
. |. .|||.||.|||| |...|.|... . .. . ....| .| ||.|. |.| . .
alsedpggpvlVHCsaGvgRtGtlvaaylmlrglleslvdaldlvrelRlqrpgmvqtpsQyrfl
|
|||||||||
0046845 | (Phosphotyrosine protein) phosphatases II | 423-567 | 5.4e-21 | 70.7 | In-house | 74-268 (284) | alignment | ||
Range on Protein: 423-567
Range on HMM: 74-268/284.0
IIPNKFIALAGPHNTrHVDDGYTHLAPEnlfepfrrlGVTDIVRLNKKMYDR---------------------------------------------TKF
.|..|||| || .. |.| . . . .|. || |.. . . |..
yikkkfIatqgPlpn.tvedFwrmvweq.........nvrvIVmltelvengrekcaqYwplegevltygdftvtllseevkddytvrtleltnlgytge
TQAGFAHHDLFFIDGTCPP-PAILESFLEITEKC------TGTAVVHCKAGLGRTGSLIGCYMMKHY--------RFNAPETIAWLRIARPGSVIGPQQT
. .| . . | .|| |..| .||.. ... |. ||||.||.|||| .| ....... .....|....|| |||.| ..|
srtvthfhytswpdhgvppspedlleflrlvrellenlpgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvqtleqy
YLVNH
..| .
rfvye
|
|||||||||
subfamily_RNGTT_pd | Subfamily RNGTT | 423-556 | 1.6e-09 | 31.7 | In-house | 13-158 (189) | alignment | ||
Range on Protein: 423-556
Range on HMM: 13-158/189.0
IIPNKFIALAGPHNTRHVDDG--YTHLAPENLFEPFR----RLGVTDIVRLNKKMYDRTKFTQAGFAHHDLFFI-DGTCPPPAILESFLEITEK-----C
.| .||... | .|. || .. |. |.. .. .||. . ....||. .... | .. | | .| . ..| .. |.
liaekflpfktplskrydddlaeenrfepsmllsylktlkvklglvidltntsryYdkeelekegikyvklqcagkgeaPeaeqvkefiklveeffkknp
TGTAVVHCKAGLGRTGSLIGCYMMKHYRFNAPETIAWLRIARPGSV
. . |||. | ||| || .|.... ... . .| . ||| .
eevigvhCthGfnRtGFlivsyLvekedwsveaavalFakaRppGi
|
|||||||||
0051299 | (Phosphotyrosine protein) phosphatases II | 424-566 | 1.9e-20 | 68.9 | In-house | 90-279 (288) | alignment | ||
Range on Protein: 424-566
Range on HMM: 90-279/288.0
IPNKFIALAGPHNTrHVDDGYTHLAPEnlfepfrrlGVTDIVRLNKKM-----------------------------------------------YDRTK
...|||| || .. |.| . . . .|. ||.|.| . .| ..
lkrkfIatqgPlpn.tvedFWrmvweq.........nvrvIvmltklvelgrekcaqYwplggsltygditvtllseevlddytvrtlevtnldlldgdg
FTQAGFAHHDLFFIDGTCPP-PAILESFLEITEKC----TGTAVVHCKAGLGRTGSLIGCYMM-----KHYRFNAPETIAWLRIARPGSVIGPQQTYLVN
... .| . . | .|. | | .||.. |. |. ||||.||.|||| .| .... |.......|....|| |||.|. |.| ..|
esrtvthfhytnwpdhgvpdspellldflrlvrkalasgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlreqRpgmvqtpeqyrfvy
|
|||||||||
0049260 | (Phosphotyrosine protein) phosphatases II | 449-566 | 6.1e-28 | 92.8 | In-house | 22-143 (152) | alignment | ||
Range on Protein: 449-566
Range on HMM: 22-143/152.0
PENLFEPFRRLGVTDIVRLNKKMYDRTKFTQAGFAHHDLFFIDGTCPPPAILESFLEI-----TEKCTGTAVVHCKAGLGRTGSLIGCYMMKhYRFNAPE
.. .. ...||.| ||.|.. ... .. .. .. |.. |...|. ..| || . .. |. .|||.||.|||| |. .|.|. ..... |
ladfwrmlkelgittivmltellelgklkceqyiqylhlpwpDhgvpdlsqlllflllfieklaldkggpvlVHCsaGvgRtgtlvaaylml.lgvslee
TIAWLRIARPGSVIGPQQTYLVN
..|..| .|||.|. |.| ...
avalvrekRpgavpnpgqlrfly
|
|||||||||
0046846 | (Phosphotyrosine protein) phosphatases II | 449-571 | 6.3e-27 | 89.8 | In-house | 36-171 (176) | alignment | ||
Range on Protein: 449-571
Range on HMM: 36-171/176.0
PENLFEPFRRLGVTDIVRLNKK--------MYDRTKFTQAGFAHHDLFFIDGTCPPPAILESFLEITEKCT---GTAVVHCKAGLGRTGSLIGCYMMKH-
.. .| ...||.| .|.|.. ... ....|. .. | . |...|. ..|...||. ... |. .|||.||.|||| |. .|....
ladflemlkelgitavvnlteevelgrlkcpnywpeleklgiqylhlpwpDhgvpdlelllellefirealkeggpvlVHCsaGigRtgtlvaayllele
YRFNAPETIAWLRIARP-GSVIGPQQTYLVNHQADM
. ... |..|..| || |.| |.| . . . . .
kglsveealalvreqRplgavqtpeQyrflyefell
|
|||||||||
0048179 | (Phosphotyrosine protein) phosphatases II | 453-565 | 3.4e-25 | 83.9 | In-house | 22-137 (144) | alignment | ||
Range on Protein: 453-565
Range on HMM: 22-137/144.0
FEPFRRLGVTDIVRLNKKmYDRTKFTQAGFAHHDLFFIDGTCPPP-AILESFLEITEKC---TGTAVVHCKAGLGRTGSLIGCYMMKHYRFNAPETIAWL
.| ...||.| ...|. . |. . ... |. .. | . | .|. ..|..|||. |.. | .|||.||.||||.|. .|.||...... |..|..
lellkklgittvinltee.yepefleregiqylhlpwpDhgvpdllellleflefieealeeggpvlVHCsaGvgRtgtlvaaylmkklglsleealalv
RIARPGSVIGPQQTYLV
| .|||.|. |.| . .
rsrrpgavpnpgqlrfL
|
|||||||||
0048076 | (Phosphotyrosine protein) phosphatases II | 453-565 | 1.2e-24 | 82.0 | In-house | 22-135 (145) | alignment | ||
Range on Protein: 453-565
Range on HMM: 22-135/145.0
FEPFRRLGVTDIVRLnkkMYDRTKFTQAGFAHHDLFFIDGTCPPP-AILESFLEITEKC---TGTAVVHCKAGLGRTGSLIGCYMMKHYRFNAPETIAWL
.| ...||.| ...| ..... ... |. .. | . | ..|. ..|..|||. |.. | .|||.||.||||.|...|.|........|.....
lellkdlgittvlnl...tselellerlgiqylylpwpDhgvpdllellleflefieealkeggpvlVHCsaGvgRtgtlvaaylmlllgvsleealelv
RIARPGSVIGPQQTYLV
| .|||.|. |.| . .
rsqrpgavpnpgqlrfl
|
|||||||||
subfamily_PRL_pd | Subfamily PRL | 454-570 | 1.2e-14 | 48.7 | In-house | 28-148 (151) | alignment | ||
Range on Protein: 454-570
Range on HMM: 28-148/151.0
EPFRRLGVTDIVRLNKKMYDRTKFTQAGFAHHDLFFIDGTCPPPAILESFLEIT-----EKCTGTAVVHCKAGLGRTGSLIGCYMMKHyRFNAPETIAWL
| ... .|. .|| . || .|. ..| .|| | ||. || ...|..||. |. | ||| |||||. |. .. . .. ... ..
eelkkeevktvvrvceptydteklekegievldlafddGavPpeevveeWlellkekfkeepkstvavhcvaGlGraPvlvalaliea.Gmkyedavefi
RIARPGSVIGPQQTYLVNHQAD
| | |.. | ..| ...|
rekrrgainskqlkflekykak
|
|||||||||
subfamily_DSP11_pd | Subfamily DSP11 | 459-552 | 3.2e-07 | 24.4 | In-house | 57-157 (178) | alignment | ||
Range on Protein: 459-552
Range on HMM: 57-157/178.0
LGV-TDIVrLNKKMYDRTKFTQAGFAHHDLFFIDGTCPPPAILESFLEITEKCT-------GTAVVHCKAGLGRTGSLIGCYMMKHYRFNAPETIAWLRI
||. |. .. |.....|. | .. |. . | ....| | .. . ||| |. ||| || |.... ... . | .
lGLvidlt.ntdryykkkeltdegvkylklncpGhevpkeelvkkfkeavkefleknkdndkligvhCthGvnrtGyliCrylidvegyepedaieafee
AR
||
ar
|
|||||||||
0036941 | (Phosphotyrosine protein) phosphatases II | 460-569 | 7.3e-19 | 63.6 | In-house | 102-272 (297) | alignment | ||
Range on Protein: 460-569
Range on HMM: 102-272/297.0
GVTDIVRLNKKMYD---------------------------------RTKFTQAGFAHHD--------------LFFIDGTCPP-PAILESFLEITEK--
.|| || |.. . . . .|. . | . | .|. ||.| .|.| .|
nvtvIvmltelvelgrekcaqywpleegesltygdftvtllsvevvllddytlrtlevtdtgngesrtvthfhytgwpdhgvpespaslldfielvrkvl
----CTGTAVVHCKAGLGRTGSLIGCYMM--------KHYRFNAPETIAWLRIARPGSVIGPQQTYLVnHQA
| .|||.||.||.|..|....| |..... .|.. .|| |||.| ..| . . ..|
kllpsggpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrfl.yea
|
|||||||||
subfamily_DSP23_pd | Subfamily DSP23 | 460-566 | 1.1e-13 | 46.1 | In-house | 31-139 (148) | alignment | ||
Range on Protein: 460-566
Range on HMM: 31-139/148.0
GVTDIVRLNKKMYDRTKFTqAGFAHHDLFfIDGTCPP-PAILESFLEITEKCT--GTAV-VHCKAGLGRTGSLIGCYMMKHYRFNAPETIAWLRIARPGS
|| .| | .. ... | . . . | || .|| . .. |... |. . || ||| | ||||... ||..|. .. | |.|| .| ||||
gvrylvslteegrphveat.pnltlvrlr.iddyhppaleqvvefvrvveeaeekneavsvhcllgrgrtgtmlacylvkerklaaaeaiaevrrlrpgs
VIGPQQTYLVN
| .| ||
vetveqeklvr
|
|||||||||
subfamily_PTEN_pd | Subfamily PTEN | 470-552 | 2.8e-09 | 32.2 | In-house | 71-156 (184) | alignment | ||
Range on Protein: 470-552
Range on HMM: 71-156/184.0
KMYDRTKFTQAgFAHhdLFFIDGTCPPPAILESFLEITE-----KCTGTAVVHCKAGLGRTGSLIGCYMMKHYRFNAP-ETIAWLRIAR
. || .||.. |. . | | . || .||...| | . . .||||||| |||| || .|..|. .. . |.... ||
rkydskkfdgr.vav..ypfdDhnppplelleeivediekwleedkknvvvvHCkaGkGRtGvlivayllkslllekaeealelfaeaR
|
|||||||||
subfamily_PTPDC1_pd | Subfamily PTPDC1 | 472-566 | 1.2e-13 | 46.0 | In-house | 73-169 (182) | alignment | ||
Range on Protein: 472-566
Range on HMM: 73-169/182.0
YDRTKFTQAGFAHHDLFFID-GTCPPPAILESFLEITEKCT-GTAVVHCKAGLGRTGSLIGCYMMKHYRFNAPETIAWLRIARPGSVIGPQQTYLVN
|| .....| ... . . | |... ||. .. .. | ||| ||||||| || ||.. . |..| ..| .| || |. .| ||.
YdlealmeqgiyvynfgwkDygvasleriLdivkvvafalqegkvavhChaGlGrtGvliacylvyakrltaekaiklvrskrpksiqtreqvelvk
|
|||||||||
subfamily_PTPMT1_pd | Subfamily PTPMT1 | 476-566 | 6.2e-09 | 30.5 | In-house | 68-162 (171) | alignment | ||
Range on Protein: 476-566
Range on HMM: 68-162/171.0
KFTQAGFAHHDLFFIDGT-CPPPAILESFLEITEKCT--GTA-VVHCKAGLGRTGSLIGCYMMKHYRFNAPETIAWLRIARPGSVIGPQQTYLVN
.... | . | .| | | . || .|. || . | |||||| ||...|..||.||..... | . |. |. . .| ...
ewkklgveqlqlatvDfteapdleklekgvefiekvaskgkrvYvHCkaGrgRsatlvacylmkkeklspeeAlkalkkkRkiirlakkqwkalq
|
|||||||||
subfamily_CDKN3_pd | Subfamily CDKN3 | 476-552 | 5.2e-06 | 20.2 | In-house | 94-174 (202) | alignment | ||
Range on Protein: 476-552
Range on HMM: 94-174/202.0
KFTQAGFAHHDLFFIDGTCPPPAILESFLE---ITEKCTGTAVVHCKAGLGRTGSLIGCYMMK-HYRFNAPETIAWLRIAR
...|||.. | . ||. | .| .|| |. | ..||| ||||. .| | .. . .. ..|. || .
lyqqaglivhhypiadglvpdiasclkileelrinlkayrktlvhcygglgrsslviaclllylddtiepkdaidklrdlk
|
|||||||||
DSPc | Dual specificity phosphatase, catalytic domain | 502-559 | 9.4e-12 | 39.9 | Pfam-A | 64-119 (133) | alignment | ||
Range on Protein: 502-559
Range on HMM: 64-119/133.0
SFLEITEKCTGTAVVHCKAGLGRTGSLIGCYMMKHYRFNAPETIAWLRIARpgSVIGP
.|.| |. .. .|||.||. |...|| .|.|| ..... | .. .. | | | |
efiekaeqkgkkvlVHCqaGisRSatliiaYlmktknlslneAyefvkerr..skisp
|
|||||||||
DSPc | Dual specificity phosphatase, catalytic domain | 502-559 | 9.4e-12 | 39.9 | In-house | 64-119 (133) | alignment | ||
Range on Protein: 502-559
Range on HMM: 64-119/133.0
SFLEITEKCTGTAVVHCKAGLGRTGSLIGCYMMKHYRFNAPETIAWLRIARpgSVIGP
.|.| |. .. .|||.||. |...|| .|.|| ..... | .. .. | | | |
efiekaeqkgkkvlVHCqaGisRSatliiaYlmktknlslneAyefvkerr..skisp
|
|||||||||
PTPc_motif_SM00404 | 502-560 | 1.1e-10 | 36.5 | In-house | 71-127 (140) | alignment | |||
Range on Protein: 502-560
Range on HMM: 71-127/140.0
SFLEITEKCTGTAVVHCKAGLGRTGSLIGCYMMKHYRFNAPETIAWLRIARpgSVIGPQ
.|.| || |. .|||.||. |...|| .|.|. . ... | . .. | . | |.
dfienaekkggkvlVHCqaGvSRSatliiaYlmryrqlslaeayefvkerR..piispn
|
|||||||||
subfamily_DSP1_pd | Subfamily DSP1 | 502-562 | 3.7e-07 | 24.4 | In-house | 86-144 (163) | alignment | ||
Range on Protein: 502-562
Range on HMM: 86-144/163.0
SFLEITEKCTGTAVVHCKAGLGRTGSLIGCYMMKHYRFNAPETIAWLRIARPgsVIGPQQT
|.. .|. | .||.||. | .|. |.||. |.. | . . |. .| | .
efidevkkknGkvlihCqaGisRsstlclaylmktkrvsleeafdfvkqrRs..iisPnag
|
|||||||||
subfamily_DSP19_pd | Subfamily DSP19 | 502-554 | 7e-07 | 23.7 | In-house | 80-132 (152) | alignment | ||
Range on Protein: 502-554
Range on HMM: 80-132/152.0
SFLEITEKCTGTAVVHCKAGLGRTGSLIGCYMMKHYRFNAPETIAWLRIARPG
|.| . . |. .|||.|| |. |.. |.||. . . |.. .| |||
dFieearskdgavlvHCnAGvSRsasvviaylmkkeelsleealelvrearpc
|
|||||||||
subfamily_DSP8_pd | Subfamily DSP8 | 502-553 | 4.5e-06 | 20.3 | In-house | 84-135 (159) | alignment | ||
Range on Protein: 502-553
Range on HMM: 84-135/159.0
SFLEITEKCTGTAVVHCKAGLGRTGSLIGCYMMKHYRFNAPETIAWLRIARP
.|.. . . |. .||. || | ... .|.||. ... |. ... ||
efidkaksengrvlvhvlaGisrsatvaiayimktlemsldeayrfvkekrp
|
|||||||||
subfamily_Slingshot_pd | Subfamily Slingshot | 503-564 | 3.2e-07 | 23.9 | In-house | 88-147 (169) | alignment | ||
Range on Protein: 503-564
Range on HMM: 88-147/169.0
FLEITEKCTGTAVVHCKAGLGRTGSLIGCYMMKHYRFNAPETIAWLRIARpgSVIGPQQTYL
|.| . | ..|||| |. |. | . | ||.|... |...... | ||| | ...|
fiekakkkgskvlvhckmGvsrsastviayamkeyglsleealeyvkerr..svikPnkgfl
|
|||||||||
subfamily_DSP10_pd | Subfamily DSP10 | 503-560 | 1.8e-06 | 21.9 | In-house | 84-139 (159) | alignment | ||
Range on Protein: 503-560
Range on HMM: 84-139/159.0
FLEITEKCTGTAVVHCKAGLGRTGSLIGCYMMKHYRFNAPETIAWLRIARPgsVIGPQ
|.| |. . .|||.||. | ... |.||| . . . . . .|| .| |
fieearkkgsrvLvhCqaGisrsatvviaYlmkhlnlslndaykfvkekrp..iisPn
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 503-561 | 3.6e-06 | 21.9 | Pfam-A | 158-225 (235) | alignment | ||
Range on Protein: 503-561
Range on HMM: 158-225/235.0
FLEITE----KCTGTAVVHCKAGLGRTGSLIGCYMM-KHY----RFNAPETIAWLRIARPGSVIGPQQ
... | ...| ||||.|| ||||... .. .. .. ... || |||.| .|
lirkvekskeaksgpvvVhCsaGvgRtgtfvaldilleqleaeeevdvlqivkelRkqRpgmvqsleq
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 503-561 | 3.6e-06 | 21.9 | In-house | 158-225 (235) | alignment | ||
Range on Protein: 503-561
Range on HMM: 158-225/235.0
FLEITE----KCTGTAVVHCKAGLGRTGSLIGCYMM-KHY----RFNAPETIAWLRIARPGSVIGPQQ
... | ...| ||||.|| ||||... .. .. .. ... || |||.| .|
lirkvekskeaksgpvvVhCsaGvgRtgtfvaldilleqleaeeevdvlqivkelRkqRpgmvqsleq
|
|||||||||
subfamily_DSP12_pd | Subfamily DSP12 | 503-553 | 4.1e-06 | 21.3 | In-house | 74-124 (155) | alignment | ||
Range on Protein: 503-553
Range on HMM: 74-124/155.0
FLEITEKCTGTAVVHCKAGLGRTGSLIGCYMMKHYRFNAPETIAWLRIARP
|.| . . |. .|||.||. | ... |.||..... . . .. ..|
FieealeeegavlvHCqagvSRSvtiviAYlmkkeklslekAlklvkekkp
|
|||||||||
DSPc_SM00195 | 504-561 | 1.1e-06 | 23.5 | In-house | 188-250 (263) | alignment | |||
Range on Protein: 504-561
Range on HMM: 188-250/263.0
LEITEKCTGTAVVHCKAGLGRTGSLIGCYMM-----KHYRFNAPETIAWLRIARPGSVIGPQQ
. ... .|. ||||.||.||||... .. .. ... |.. || |||.| .|
kkskstssgpivVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleq
|
|||||||||
PTPc_SM00194 | 504-561 | 1.1e-06 | 23.5 | In-house | 188-250 (263) | alignment | |||
Range on Protein: 504-561
Range on HMM: 188-250/263.0
LEITEKCTGTAVVHCKAGLGRTGSLIGCYMM-----KHYRFNAPETIAWLRIARPGSVIGPQQ
. ... .|. ||||.||.||||... .. .. ... |.. || |||.| .|
kkskstssgpivVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleq
|
|||||||||
PTPc_DSPc_SM00012 | 505-556 | 1.6e-07 | 26.8 | In-house | 27-90 (105) | alignment | |||
Range on Protein: 505-556
Range on HMM: 27-90/105.0
EITEKC------TGTAVVHCKAGLGRTGSLIGCYMMKHYR------FNAPETIAWLRIARPGSV
. ..|. .. ||||.|| |||| .. ... . .. ... || |||.|
ravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgmv
|
|||||||||
subfamily_DSP14_pd | Subfamily DSP14 | 508-558 | 1.2e-06 | 22.6 | In-house | 80-128 (157) | alignment | ||
Range on Protein: 508-558
Range on HMM: 80-128/157.0
EKCTGTAVVHCKAGLGRTGSLIGCYMMKHYRFNAPETIAWLRIARPgsVIG
.| | ..|||.|| | || |.||. . . |. ... ||| .|
kkkggktlvhCvaGvSRSAslclaylmkyeklsLreayklvksaRp..iir
|