Gene MbreMKP-Un-2 in Monosiga brevicollis

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family DSP
Subfamily DSP_MKP-unclassified
Protein sequence
ID Type Fasta BLAST phosphatome Note
MbreP003_AA protein Get Run
MbreP003_AA_341-487 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
Rhodanese Rhodanese-like domain 201-306 4.6e-08 25.6 Pfam-A 11-109 (113) alignment 
Range on Protein: 201-306
Range on HMM: 11-109/113.0
PEQLLMLDCRAGLGFKTSSIKGAVSVQYSGLmlrrlrkqG---HVRIQLKHLQVsdEAAVAKRSDPNTLVVVYDeDSTVVEPEGNAAILLRILESEGV-K
 |... ||.|    .... |.|||.| .. |              ... |  .    . ..|. |... ||||.  |.     . |. |  ||.. |  .
kekvvllDvRspeeyakghIpgAvnvpldsl........yprrdlffkdklaee..leesgkkldkdktvvvyc.rsgnrsggaaalllalilkelgykn

AVFLKGGITA
  .|.||..|
vyvLdGGfea
0044763 (Phosphotyrosine protein) phosphatases II 337-485 2.3e-33 110.7 In-house 16-172 (178) alignment 
Range on Protein: 337-485
Range on HMM: 16-172/178.0
PRLATVPATVVFDHLVLGNQHQGTDPAFLARNRITHVINVTETPFANGLPNL--------VRCMQIPLLDGAHHDLLSVVPEALRFIEGCR-REHGRVLV
.|    .|. ....| ||.. .  |...| .. |||..|.||.   . |...        .. ..||. |.   |||. ..|...||| .. ...|.|||
ersdyinaseilpglylgslppaddlellkelgithivnlteelelgflkcdpywpeeagiqylhipipDhgvpdllehflefvefieealdekggpvlV

YCSNGYSRAVAVVMAYMMATRSYNYDAALQLLQAIRPrIAPHDSFLKQLRDFQSFLSN
.|| |..|. ..|.||.| ........|..|... || | |....|.||..|...| .
HCsaGvgRsgtlvaaylmkklglsleeaielvrerRp.ivpnpgqlrqLyefelrllk
0041856 (Phosphotyrosine protein) phosphatases II 337-485 6.8e-25 83.1 In-house 12-174 (182) alignment 
Range on Protein: 337-485
Range on HMM: 12-174/182.0
PRLATVPATVVFDHLVLGNQHQ--------------GTDPAFLARNRITHVINVTETPFANGLP--NLVRCMQIPLLDGAHHDllsvVPEALRFIEGCRR
|   . . . . ..|.||....                .  .| ...||...|.|| .    |   . .. ...|  |.   |    ..|.|.||| ...
pydhsrdldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlteelywpellerlgiqylylpwpDhgvpd....ldelldfieevle

EHGRVLVYCSNGYSRAVAVVMAYMMATRSYNYDAALQLLQAIRP--RIAPHDSFLKQLRDFQSFLSN
|.|.||| || | .|. ..|.||.| ....... |..|..  ||   | |.  |. ||  .. .| .
eggpvlVHCsaGvgRtgtlvaaylmkklgvsleeavklvrsrRpgmvitpnqyfflqlallellllk
subfamily_DSP10_pd Subfamily DSP10 338-488 5.1e-32 104.9 In-house 8-158 (159) alignment 
Range on Protein: 338-488
Range on HMM: 8-158/159.0
RLATVPATVVFDHLVLGNQHQGTDPAFLARNRITHVINVTETPFANGLPNLVRCMQIPLLDGAHHDLLSVVPEALRFIEGCRREHGRVLVYCSNGYSRAV
 . |.||. |. .|.||.... .| . | | .||.|.||| .   .   . .. ..||. |  ...|     ||| |||  |..  ||||.|  | ||..
dietapasqvlpfLflGsekdaadldaldrlnitavlnvttsvPnefeeealkYkripvsDtskqnlkqyfeealefieearkkgsrvLvhCqaGisrsa

AVVMAYMMATRSYNYDAALQLLQAIRPRIAPHDSFLKQLRDFQSFLSNAQT
.||.||.|. .. .   | .. .  || |.|  .|. || .|   |.. ..
tvviaYlmkhlnlslndaykfvkekrpiisPnLnfmGqLlefekelnkska
subfamily_STYXL1_pd Subfamily STYXL1 338-481 4.3e-24 78.5 In-house 6-151 (157) alignment 
Range on Protein: 338-481
Range on HMM: 6-151/157.0
RLATVPATVVFDHLVLGNQHQGTDPAFLARNRITHVINVTET--PFANGLPNLVRCMQIPLLDGAHHDLLSVVPEALRFIEGCRREHGRVLVYCSNGYSR
.| | |  |. ..| ||| .| ..||     ..  ..||.    .. .|... .. ..|.. |  . |||. . || .|||  ..|   |||.  .| ||
elktyPvevlPgklylGnykqaqnpaikkdlkvkahvnvsmdadkliagvadvakllhiavedeneadllerlkeavqfiekhkkegevvlvfsnkGisr

AVAVVMAYMMATRSYNYDAALQLLQAIRPRIAPHDSFLKQLRDFQS
..||..||.|  .  ..  |.. |.  .. . |. .|..||.... 
saaviiaylmyskkitlkkaykylkkCkenvkPnrafveqlseWek
subfamily_Choan-DSP_MKP-1_pd Subfamily Choan-DSP_MKP-1 338-479 4.7e-21 68.8 In-house 2-143 (148) alignment 
Range on Protein: 338-479
Range on HMM: 2-143/148.0
RLATVPATVVFDHLVLGNQHQGTDPAFLARNRITHVINVTEtPFANGLP-NLVRCMQIPLLDGAHHDLLSVVPEALRFIEGCRREHGRVLVYCSNGYSRA
 | | |. .   .| ||.... .|   |.   .|...| |.    | |    .. ....| |  ..|| .. ...  |..  . | .|||| .  | ||.
aLrtfpseikdafLFlGskksaadlealkalgvtrivnatk.erdnaldqrgieYlhvaldDkpkedlsaiFediiafvrkakdeGrrvLvhlqmGvsrs

VAVVMAYMMATRSYNYDAALQLLQAIRPRIAPHDSFLKQLRDF
 |....... ..      ||.| .  |. . |.  ||||| ..
salallwlidfkrvslkealalvkskrryvdpnlgfLkqLael
subfamily_MKPLT_pd Subfamily MKPLT 338-481 1.2e-18 61.2 In-house 16-158 (164) alignment 
Range on Protein: 338-481
Range on HMM: 16-158/164.0
RLATVPATVVFDHLVLGNQHQGTDPAFLARNRITHVINVTETpFANGLPNLVRCMQIPLLDGAHHDLLSVVPEALRFIEGCRREHGRVLVYCSNGYSRAV
|. . |. |. |.| ||| .. |.   |    |||..||..   ..  |. |  .|. . | ... | | .  |  |.       |||||.|  | ||. 
rikiypsvvledtlylGnakhatnekvlkdlkithivnvsqe.kkdafpksveYlqvkvedesdeqlssfleraakfladaidsGGrvlvhcvqGksrss

AVVMAYMMATRSYNYDAALQLLQAIRPRIAPHDSFLKQLRDFQS
.| .|...  . . .. | . |.  |  .||   |||||  |. 
svtvafLikskgwtlkeayeylkerrsivapnrGflkqlakfee
subfamily_MKPLV_pd Subfamily MKPLV 338-481 1.2e-18 61.2 In-house 16-158 (164) alignment 
Range on Protein: 338-481
Range on HMM: 16-158/164.0
RLATVPATVVFDHLVLGNQHQGTDPAFLARNRITHVINVTETpFANGLPNLVRCMQIPLLDGAHHDLLSVVPEALRFIEGCRREHGRVLVYCSNGYSRAV
|. . |. |. |.| ||| .. |.   |    |||..||..   ..  |. |  .|. . | ... | | .  |  |.       |||||.|  | ||. 
rikiypsvvledtlylGnakhatnekvlkdlkithivnvsqe.kkdafpksveYlqvkvedesdeqlssfleraakfladaidsGGrvlvhcvqGksrss

AVVMAYMMATRSYNYDAALQLLQAIRPRIAPHDSFLKQLRDFQS
.| .|...  . . .. | . |.  |  .||   |||||  |. 
svtvafLikskgwtlkeayeylkerrsivapnrGflkqlakfee
subfamily_LRR-DSP_pd Subfamily LRR-DSP 340-484 5.2e-20 65.6 In-house 117-259 (263) alignment 
Range on Protein: 340-484
Range on HMM: 117-259/263.0
ATVPATvVFDHLVLGNQHQGTDPAFLARNRITHV-INVTEtpFANGLPNLVRCMQI-PLLDGAHHDLLSVVPEALRFIEGCRrEHGRVLVYCSNGYSRAV
..||   . |.| || ..  .. ..|  . .||. . |..  |    |.| . . |  . |  . |.     |   |||  | ..| |||.|  | ||. 
ssvPde.iidklflGgldsannksilkdlgvthillavad..fePlfPklfkylsiddiedvdeadisqhfeetnafieeGr.kkGGvlvhcraGvsrss

AVVMAYMMATRSYNYDAALQLLQAIRPRIAPHDSFLKQLRDFQSFLS
..|..|.|  .. ..  || | .  |||| |   |..||. ..  |.
tlvisylmkkqrlkfkealdlvikkrpriqPnpGfkdqlkkyekklf
subfamily_DSP6_pd Subfamily DSP6 342-484 8.1e-31 100.7 In-house 13-155 (158) alignment 
Range on Protein: 342-484
Range on HMM: 13-155/158.0
VPATVvFDHLVLGNQHQGTDPAFLARNRITHVINVTET-PFANGLPNLVRCMQIPLLDGAHHDLLSVVPEALRFIEGCRREHGRVLVYCSNGYSRAVAVV
.|...  ..| ||.... ..   |.. .| .|.|||.  | .    . .. .|||. | ....| . .|||..||.  |...  |||.|  | ||.|.|.
fpvei.lpllylGsakdasnlevlkklkikyvlnvtsnlpnkfeesgelkylqipiedhlsqnlakffPeaiefidearskkskvlvhClaGisrsvtvt

MAYMMATRSYNYDAALQLLQAIRPRIAPHDSFLKQLRDFQSFLS
.||.| .. .  . | .|... .. |.|  .|..|| ||.. |.
laylmkklalslndaydlvkkrksnisPnfnfmgqlldferslr
subfamily_DSP8_pd Subfamily DSP8 342-486 9e-26 84.3 In-house 13-157 (159) alignment 
Range on Protein: 342-486
Range on HMM: 13-157/159.0
VPATVVFDHLVLGNQHQGTDPAFLARNRITHVINVTETPF-ANGLPNlVRCMQIPLLDGAHHDLLSVVPEALRFIEGCRREHGRVLVYCSNGYSRAVAVV
|  | . ..| || |..  .  .| .. |..|.|. ..    . |.. .. ...|. |  . .|| . .... ||. ...|.|||||..  | ||. .|.
vgptrilknlylGsqkdvlseellsklgisyvlnasnscpkleelke.skflrvPvkDkydekllpwfdksvefidkaksengrvlvhvlaGisrsatva

MAYMMATRSYNYDAALQLLQAIRPRIAPHDSFLKQLRDFQSFLSNA
.||.| | . ..| | . ..  || | |   ||.|| ...  | . 
iayimktlemsldeayrfvkekrptispnlnflgqLleyekelkll
PTEN_1 342-484 2.7e-22 74.5 In-house 38-192 (196) alignment 
Range on Protein: 342-484
Range on HMM: 38-192/196.0
VPAT-VVFDHLVLGNQHQG-TDPAFLARNRITHVINVTETPFAN---G-----LPNLVRCMQIPLLDGAHHDLLSVVPEALRFIEGCRR--EHGRVLVYC
.| .  ....| .|....   |   |  . ||.|.|..| .  .   .       . |.  ..|  |    .| ..  .. .||| ...  ... |||.|
rpllqeideglyrgslkdvaadldnlkedgitlvvnlseeeelsgrsydleeffksgveylhfpieDhgapslselfdicksfiewllsdpngnvVlVHC

SNGYSRAVAVVMAYMMATRSYNYDAALQLLQAIRPRIAPHDSFLKQLRDFQSFLS
  | .| . ||.||.|... ...| ||.|... ||..||. .....|. ... | 
kaGlgRsGtvvaayLmykgkltadeAlelvrekRppgapnspsqerlleyfaell
0045098 (Phosphotyrosine protein) phosphatases II 342-482 3.8e-21 71.1 In-house 20-270 (278) alignment 
Range on Protein: 342-482
Range on HMM: 20-270/278.0
VPATVVFDHLVLGNQH-----------------------------------------QGTDPAFLARNRITHVINVTET---------------------
 .   ....| |||..                                            .  .|  ..||.....||                      
gipseitpalylgnldknRykdilpydhsrVkdYINAsyidgypkkfIatqgPlpstvadfwrmlwelgitvivmltelvelgrekcaqywpeggsltyg

---------------------------PFANGLPNLVRCMQI-PLLDGAHHDLL--SVVPEALRFIEGCRR--------------EHGRVLVYCSNGYSR
                            .... .. |. ... |  |.  ..|   . . |.|.||. ...              ..|.||| || | .|
dftvtllseevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllsslllldsggpvlVHCsaGvgR

AVAVVMAYMMATR---SYNYDAALQLLQAIRPR-IAPHDSFLKQLRDFQSF
. ..|.||.| ..    .... |.. |.  ||  . .. .....| .|.  
tGtlvaaylmlelleggvdlleavkelrsqRpglavqnleqyrflyeflle
subfamily_DSP3_pd Subfamily DSP3 342-484 4.2e-20 66.0 In-house 9-158 (162) alignment 
Range on Protein: 342-484
Range on HMM: 9-158/162.0
VPATVVFDHLVLGNQHQGTDPAFLARNRITHVINVTETPFA--NGLPNL-----VRCMQIPLLDGAHHDLLSVVPEALRFIEGC-RREHGRVLVYCSNGY
  .  |...| .|...  .|   |..  ||||.| .|. |.  .  ..      .. . ... |  . ||     .| .||.    ...|.||| |  |.
kevdevypklyvgdeavakdkskLkklGithvlnaaegrfskvdtgaefykdleikylGlevdDvpefdlskyFetaakfidealsqkegkvlvhcvvGv

SRAVAVVMAYMMATRSYNYDAALQLLQAIRpRIAPHDSFLKQLRDFQSFLS
||. ..|.||.| .|. .   |..  .. | .| | . |||||..... |.
sRsatlvlayLmirrkmtlveairtvrkkR.eilPneGFlkqLaeldeelk
subfamily_DSP1_pd Subfamily DSP1 343-484 2e-30 100.0 In-house 17-157 (163) alignment 
Range on Protein: 343-484
Range on HMM: 17-157/163.0
PATVVFDHLVLGNQHQGTDPAFLARNRITHVINVTETpFANGLPNLVRCMQIPLLDGAHHDLLSVVPEALRFIEGCRREHGRVLVYCSNGYSRAVAVVMA
| . . |.| || ... ..  .|....||...||...   |  ..| . ....| |  . |. .|  |.. ||. .....|.||..|  | ||. ....|
PvekildfLylGsetvasnleiLkslgitailnvske.ldnvfedlfeYkklkleDspkadislvfeeviefidevkkknGkvlihCqaGisRsstlcla

YMMATRSYNYDAALQLLQAIRPRIAPHDSFLKQLRDFQSFLS
|.| |. .... | .. .  |. | |  .| .|| .... | 
ylmktkrvsleeafdfvkqrRsiisPnagFvlqLlnyekkll
0046846 (Phosphotyrosine protein) phosphatases II 343-482 3.4e-23 77.7 In-house 11-171 (176) alignment 
Range on Protein: 343-482
Range on HMM: 11-171/176.0
PATVVFDHLVLGNQH----------QGTDPAFLARNRITHVINVTET------------PFanGLPNLVRCMQIPLLDGAHHDLlSVVPEALRFIEGCRR
. . . ..|.||.              .. ..| ...||.|.|.||             |      . .. ...|  |.   || . ..|.|.||. ...
dldyinanlilgsrpiatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpe..leklgiqylhlpwpDhgvpdl.elllellefirealk

EHGRVLVYCSNGYSRAVAVVMAYMMAT-RSYNYDAALQLLQAIRP-RIAPHDSFLKQLRDFQSF
|.|.||| || | .|. ..|.||.. . . .... ||.|....|| .. ........|..|  .
eggpvlVHCsaGigRtgtlvaayllelekglsveealalvreqRplgavqtpeQyrflyefell
subfamily_DSP19_pd Subfamily DSP19 344-481 6e-33 108.3 In-house 12-148 (152) alignment 
Range on Protein: 344-481
Range on HMM: 12-148/152.0
ATVVFDHLVLGNQHQGTDPAFLARNRITHVINVTETpFANGLPNLVRCMQIPLLDGAHHDLLSVVPEALRFIEGCRREHGRVLVYCSNGYSRAVAVVMAY
...| ..| || |   .|   | ...|||..||.     |  |. . ...|..||   .||||. .||| |||  |...|.||| |. | ||...||.||
vgeveprlylgsqdvaadkeilkekkitHilnvatg.vpnvfpkdftylsieilDlpetdllsylkealdFieearskdgavlvHCnAGvSRsasvviay

MMATRSYNYDAALQLLQAIRPRIAPHDSFLKQLRDFQS
.|.... ..  ||.|....|| | | . |.|||.....
lmkkeelsleealelvrearpcikPneGFikqLkeyea
subfamily_Slingshot_pd Subfamily Slingshot 344-488 2.5e-25 82.8 In-house 19-162 (169) alignment 
Range on Protein: 344-488
Range on HMM: 19-162/169.0
ATVVFDHLVLGNQHQGTDPAFLARNRITHVINVTETpFANGLPNLVRCMQIPLLDGAHHDLLSVVPEALRFIEGCRREHGRVLVYCSNGYSRAVAVVMAY
|. .|||. || .   ..   | .|......|||.    |  |. .. ..| . |  ..|||.   |. .||| ..... .|||.|  | ||. ..|.||
askifdhvylGsewnasnleelkengveyilnvtke.idnffpekfeylnirvydeeetdllkywnetykfiekakkkgskvlvhckmGvsrsastviay

MMATRSYNYDAALQLLQAIRPRIAPHDSFLKQLRDFQSFLSNAQT
 | . ..... ||. ..  |  | | ..|||||. ..  |. .. 
amkeyglsleealeyvkerrsvikPnkgflkqleeyeGileaskq
0036282 (Phosphotyrosine protein) phosphatases II 344-485 1.1e-22 76.0 In-house 12-171 (174) alignment 
Range on Protein: 344-485
Range on HMM: 12-171/174.0
ATVVFDHLVLGNQHQGtDPAFLARNRITHVINVTETPFAN--------------GLPNLVRCMQIPLLDGAHHDLLSvVPEALRFIEGCRRE--HGRVLV
 ... ..|..|.     . ..| ...||.|....|    .                .. .. ...|  |.   ||   . |...|.| .. |  .| |||
lsyitprliagqgpla.fwemlkelgittvvmlleekelglykcinywpelredlerlgiqylylpwpDhgvpdlsi.llefvkfveealsedpggpvlV

YCSNGYSRAVAVVMAYMMATRSY-NYDAALQLLQAIR---PRIAPHDSFLKQLRDFQSFLSN
 || | .|. ..|.||.| .. . ... ||.|....|   |.. ...|....|..|...||.
HCsaGvgRtGtlvaaylmlrglleslvdaldlvrelRlqrpgmvqtpsQyrflyyfekllsg
0051082 (Phosphotyrosine protein) phosphatases II 344-478 1.4e-18 62.4 In-house 8-148 (151) alignment 
Range on Protein: 344-478
Range on HMM: 8-148/151.0
ATVVFDHLVLGNQHQGTDPAFLARNRITHVINVTETPFANGLPNL-----VRCMQIPLLDGAHHDLLSVVPEALRFIEGCRRE-HGRVLVYCSNGYSRAV
.. | ..| ....    . ..|... |....|.....  . .|..     .. ..||.||   ..|    ...|.|.| ...  .| |||.|| | .|  
fsyvtgglyrsggpladflellkelgiktivnlrseeergycpeylpelgievlhipildwpdpglplsfdavleflellldkkngpvlvHCsaGkgRTG

AVVMAYMMAtRSYNYDAALQLLQAIRP-RIAPHDSFLKQLRD
..|..|.|. . .....||. ....||  . |.. ||.||..
tlvalylml.lgvsleealeeyrlkrpgvvqpnqqflfqlfa
0048179 (Phosphotyrosine protein) phosphatases II 346-482 1.2e-28 95.0 In-house 6-143 (144) alignment 
Range on Protein: 346-482
Range on HMM: 6-143/144.0
VVFDHLVLGNQHQGTDPAFLARNRITHVINVTETPFANGLPNLV-RCMQIPLLDGAHHDLLSVVPEALRFIEGCRREHGRVLVYCSNGYSRAVAVVMAYM
 ....| ||..    | ..|... ||.|||.||.   . | . . . ...|. |    |||. ..|.|.||| ...|.|.|||.|| |..|. ..|.||.
eilpglylgslptaldlellkklgittvinlteeyepefleregiqylhlpwpDhgvpdllellleflefieealeeggpvlVHCsaGvgRtgtlvaayl

MATRSYNYDAALQLLQAIRPRIAPHDSFLKQLRDFQSF
| .. .... ||.|....|| . |....|..|......
mkklglsleealalvrsrrpgavpnpgqlrfLleyekl
0048076 (Phosphotyrosine protein) phosphatases II 346-483 3e-28 93.7 In-house 6-142 (145) alignment 
Range on Protein: 346-483
Range on HMM: 6-142/145.0
VVFDHLVLGNQHQGTDPAFLARNRITHVINVTETPfANGLPNLVRCMQIPLLDGAHHDLLSVVPEALRFIEGCRREHGRVLVYCSNGYSRAVAVVMAYMM
 ....| ||...   | ..|... ||.|.|.| ..  .  .. .. ...|. |    |||. ..|.|.||| ...|.|.|||.|| |..|. ..|.||.|
eilpglylgslptaldlellkdlgittvlnltsel.ellerlgiqylylpwpDhgvpdllellleflefieealkeggpvlVHCsaGvgRtgtlvaaylm

ATRSYNYDAALQLLQAIRPRIAPHDSFLKQLRDFQSFL
 ....... ||.|... || . |....|..|..|.  |
lllgvsleealelvrsqrpgavpnpgqlrflyefelel
0037934 (Phosphotyrosine protein) phosphatases II 346-482 4.1e-20 67.8 In-house 41-240 (243) alignment 
Range on Protein: 346-482
Range on HMM: 41-240/243.0
VVFDHLVLGNQ--------HQGTDPAFLARNRITHVINVTETP--------------------------------------------FANGLPNLVRCMQ
 |...| ....        .  ..  .| ...||.....||.                                               .   . .. ..
yvtprliatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqywpgevtygdftvtllseehlddytvrtlllenldlddltrlvihyhy

IPLLD----GAHHDLLSVVPEALRFIEG-----CRREHGRVLVYCSNGYSRAVAVVMAYMMATR-SYNYDAALQLLQAIRPR-IAPHDSFLKQLRDFQSF
.|  |      . |||. . |.  |||      .. ..|.||| || | .|. ....||.| .. ..... |..||.. ||  . .  |....|...  .
lpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgRtGtliaaylmllllgvdleeavkllreqRpgkavqtpsqyrflyealle
PTPc_motif_SM00404 347-480 3.1e-31 103.1 In-house 5-138 (140) alignment 
Range on Protein: 347-480
Range on HMM: 5-138/140.0
VFDHLVLGNQHQGTDPAFLARNRITHVINVTETPFANGLPNLVRCMQIPLLDGAHHDLLSVVPEALRFIEGCRREHGRVLVYCSNGYSRAVAVVMAYMMA
. .|| ||.. . ..||.|. ..|||||||||.  ..   . .. .|||| |    .|.   ...|.||| .....|.|||.|  |.|| .....||.| 
ilphlylgskskaqnpallkklgithvinvteevsltkensgfqilqiplddnekdklskyldkvldfienaekkggkvlVHCqaGvSRSatliiaYlmr

TRSYNYDAALQLLQAIRPRIAPHDSFLKQLRDFQ
.|......|.....  ||.| |  .|..|| ...
yrqlslaeayefvkerRpiispnlnfvrqLieye
subfamily_DSP12_pd Subfamily DSP12 347-491 2.7e-30 99.8 In-house 5-151 (155) alignment 
Range on Protein: 347-491
Range on HMM: 5-151/155.0
VFDHLVLGNQHQGTDPAFLARNRITHVINVTETPF--ANGLPNLVRCMQIPLLDGAHHDLLSVVPEALRFIEGCRREHGRVLVYCSNGYSRAVAVVMAYM
. . | ||. .. .....|.   ||||. |....    .  .. |.. .|..||  . |.||  .||..||| .. |.| ||| |  | || |..|.||.
ilpglylggleavqeeellkelkithvlsvikeelpehklkkgkvstkfiqilDepeediLshldeavdFieealeeegavlvHCqagvSRSvtiviAYl

MATRSYNYDAALQLLQAIRPRIAPHDSFLKQLRDFQSFLSNAQTPER
| .   . . ||.|.....|.| | ..||.||. |.    . .| ..
mkkeklslekAlklvkekkpeiepNegFleQLklfekmgckvdtsnk
subfamily_DSP15_pd Subfamily DSP15 347-483 7.6e-26 85.0 In-house 5-139 (151) alignment 
Range on Protein: 347-483
Range on HMM: 5-139/151.0
VFDHLVLGNQHQGTDPAFLARNRITHVINVTETPfANGLPNlVRCMQIPLLDGAHHDLLSVVPEALRFIEGCRREHGRVLVYCSNGYSRAVAVVMAYMMA
|   | ||| ..  | . | ...|||...| . .  . |.. ..   |.. | .. .| ... |. .||  || . . |||.|  | ||.| .|.||.|.
vlpglylgnfrdskdeelLkeknithilsvhdna.kkllkd.ieYkciaasDtpsaklskffkesvefihkcRlkeenvlvhClaGvsRsvtlvvaYlmt

TRSYNYDAALQLLQAIRPRIAPHDSFLKQLRDFQSFL
  ..|.  ||. ..| |    |   | .||.... . 
vtelnwrdalevikaaRsvanPnfGfkrqlkeyektk
subfamily_DSP14_pd Subfamily DSP14 347-486 5.8e-25 82.1 In-house 10-147 (157) alignment 
Range on Protein: 347-486
Range on HMM: 10-147/157.0
VFDHLVLGnQHQGTDPAFLARNRITHVINVTETPFANGLPNlVRCMQIPLLDGAHHDLLSVVPEALRFIEGCRREHGRVLVYCSNGYSRAVAVVMAYMMA
. ..| |.     .... |....||..||||    .. |.. .. ...|. |  ...| .   |.   ||  ....|..||.| .| ||  ....||.| 
itpsLfls.gvaalskellkkkkitliinvtvelpntklkd.iervkvpveDnpeaklakhfdevadkieevkkkggktlvhCvaGvSRSAslclaylmk

TRSYNYDAALQLLQAIRPRIAPHDSFLKQLRDFQSFLSNA
... .   | .|....|| | |   | |||.|. . | . 
yeklsLreayklvksaRpiirPNvGFwkqlidyEkklkgk
0042113 (Phosphotyrosine protein) phosphatases II 347-481 1.3e-18 62.8 In-house 50-240 (245) alignment 
Range on Protein: 347-481
Range on HMM: 50-240/245.0
VFDHLVLGNQHQGTDPA----FLARNRITHVINVTETP---------------------------------------------FANGLPNLVRCMQIPLL
. ... .... .  ...    .| ...||.....||.                                                .   . .. ...|  
itpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywplgesltygdftvtllseehlddytvrtlevtnlgddesrevihyhylpwp

DGAHHDLLSVVPEALRFIEGCRR--EHGRVLVYCSNGYSRAVAVVMAYMM-----ATRSYNYDAALQLLQAIRPRIAPHDSFLKQLRDFQS
|.   |||. . ..|.|.. ...  ..|.||| || | .|. ....||.|     ... .. . |.. |.  || . . .|....|...  
dhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylmleqlekelgvsleeavkelrsqRpgavqtpsqyrflyeall
0043147 (Phosphotyrosine protein) phosphatases II 349-483 1.2e-25 85.6 In-house 24-160 (172) alignment 
Range on Protein: 349-483
Range on HMM: 24-160/172.0
DHLVLGNQHQGTDPAFLARNRITHVINVTET--PFANGLPNLVRCMQIPLLDGAHHdLLSVVPEALRFIEG--CRREHGRVLVYCSNGYSRAVAVVMAYM
... ... .   . ..| .. |||..|.||   .  .  .. .. . .|  |.    ||....|.|.||.   .....|.||| || | .|....|.||.
atqgplrntladfwrmlkelgithivnltellydpellerlgiqylylpwpDhgvp.llellleflefidellalspggpvlVHCsaGvgRtgtlvaayl

MAtRSYNYDAALQLLQAIRPRIAPHDSFLKQLRDFQSFL
|  ...... |..|... || . ...|....|..|...|
ml.lglsleeavalvrekRpgavqnpsqyrflyyfekll
0049260 (Phosphotyrosine protein) phosphatases II 349-483 5.8e-22 73.4 In-house 13-149 (152) alignment 
Range on Protein: 349-483
Range on HMM: 13-149/152.0
DHLVLGNQHQGTDPAFLARNRITHVINVTETPFA--NGLPNLVRCMQIPLLDGAHHDLLSVVPEALRFIEG-CRREHGRVLVYCSNGYSRAVAVVMAYMM
 .. .|...   .  .| .. ||.....||       . ... . ...|  |.   ||  .....|.|||  .....|.||| || | .|. ..|.||.|
atqgpgpntladfwrmlkelgittivmltellelgklkceqyiqylhlpwpDhgvpdlsqlllflllfieklaldkggpvlVHCsaGvgRtgtlvaaylm

AtRSYNYDAALQLLQAIRPRIAPHDSFLKQLRDFQSFL
  . .... |..|... || . |. ..|..| .|...|
l.lgvsleeavalvrekRpgavpnpgqlrflyefekll
0051429 (Phosphotyrosine protein) phosphatases II 350-479 3.5e-13 45.3 In-house 23-220 (272) alignment 
Range on Protein: 350-479
Range on HMM: 23-220/272.0
HLVLGNQH---QGTDPAFLARNRITHVINVTETPFANGLP-----NLVRCMQIPLLDGAHHDLLSVV---------------------------------
 | ....       | ..|....|.........   . |.       .| ...|.|| .. . |                                    
rlyrsggplpltaadfwrlkelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseellldyilrellltlllsagearev

---------------PEALRFIEGCRReHGRVLVYCSNGYSRAVAVVMAYMMAtRSYN--------------YDAALQLLQAIRPRIAPHDSFLKQLRDF
                . |...| ... .|.||| || | .|   ||...... .  .              ...|.. |.|.|| . ... ....|...
mhlhytdwpdhgvpqeallellellld.ggpvlvHCsaGkdRTGtvvalllll.lgvsletivddYlltnlyleeaveelraqrpgavqteeqylflyea
DSPc Dual specificity phosphatase, catalytic domain 353-481 4.2e-28 92.9 Pfam-A 3-132 (133) alignment 
Range on Protein: 353-481
Range on HMM: 3-132/133.0
LGNQHQGTdPAFLARNRITHVINVTETPFA--NGLPNLVRCMQIPLLDGAHHDLLSVVPEALRFIEGCRREHGRVLVYCSNGYSRAVAVVMAYMMATRSY
||.. . . .|.|. . ||.|||||..  .     ..  . ..||. |    .. .  .|| .||| .......|||.|  |.||  ....||.| |...
lgskstas.lalleklgitlvinvtkevpnnnaikkseieylripvedetetkiskeleeavefiekaeqkgkkvlVHCqaGisRSatliiaYlmktknl

NYDAALQLLQAIRPRIAPHDSFLKQLRDFQS
... |.....  |..| | ..||.||.....
slneAyefvkerrskispnagflrqLleyer
DSPc Dual specificity phosphatase, catalytic domain 353-481 4.2e-28 92.9 In-house 3-132 (133) alignment 
Range on Protein: 353-481
Range on HMM: 3-132/133.0
LGNQHQGTdPAFLARNRITHVINVTETPFA--NGLPNLVRCMQIPLLDGAHHDLLSVVPEALRFIEGCRREHGRVLVYCSNGYSRAVAVVMAYMMATRSY
||.. . . .|.|. . ||.|||||..  .     ..  . ..||. |    .. .  .|| .||| .......|||.|  |.||  ....||.| |...
lgskstas.lalleklgitlvinvtkevpnnnaikkseieylripvedetetkiskeleeavefiekaeqkgkkvlVHCqaGisRSatliiaYlmktknl

NYDAALQLLQAIRPRIAPHDSFLKQLRDFQS
... |.....  |..| | ..||.||.....
slneAyefvkerrskispnagflrqLleyer
0040439 (Phosphotyrosine protein) phosphatases II 363-482 2.7e-20 68.5 In-house 72-244 (249) alignment 
Range on Protein: 363-482
Range on HMM: 72-244/249.0
AFLARNRITHVINVTETPFAN------------------------------------------GLPNLVRCMQIPLLDGAHHDLLSVVPEALRFIEGCRR
 .| ...||.....|..   .                                          . .. .....|. .|  .|.. . ....|.||| .| 
rmlwelgitvivmLtslvelgrekcaqywplggsleygdftvtllsvevkddytvrtleltnlydgesrtvlhiqytdwpdhgvppsfedlldfieavrk

------EHGRVLVYCSNGYSRAVAVVMAYMM-----ATRSYNYDAALQLLQAIRPRIAPHDSFLKQLRDFQSF
      ..|.||| ||.| .|. ....||.|      .. .... |..||.  || . . ......| ..  .
aleelpkggpvlVHCsaGvgRtGtfiaaylmleqlekelgvdleeavkllrsqRpgavqnpeqyrflyealle
0045450 (Phosphotyrosine protein) phosphatases II 363-481 2.5e-18 62.3 In-house 108-301 (307) alignment 
Range on Protein: 363-481
Range on HMM: 108-301/307.0
A-----------------FLARNRITHVINVTETPFAN--------------------------------------------GLPNLVRCMQIPLLDGAH
.                 .| ....|.....||.   .                                            |  .  ...... ..  .
kfIatqgPlpetvedFwrmlweqgvtvivmltelvelgrekcaqywPdegeeltygnftvtllseehldgytvrtlevtdldgtgesrtvthfhytgwpd

HDLLSVVPEALRFIEGCRR------EHGRVLVYCSNGYSRAVAVVMAYMMATRS--------YNYDAALQLLQAIRPRIAPHDSFLKQLRDFQS
|.. . . |.|.||| .|.      ..|.||| || | .|. ....||.| ..         .... |..||.. || . .  .....|...  
hgvppsfeelldfieevrkaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrflyeall
0039614 (Phosphotyrosine protein) phosphatases II 364-482 8.7e-16 53.7 In-house 120-287 (297) alignment 
Range on Protein: 364-482
Range on HMM: 120-287/297.0
FLARNRITHVINVTETPFAN----------------------------------------GLPNL---VRCMQIPllDGAHHDLLSVVPEALRFIEGCRR
.. ....|.....|..   .                                        | .     . .. .|  |.   ..|... |.|.... ...
mvweqgvtvivmLtklvelgrkcaqywpeeggtygdftvtllkvehldgytvrtlevtnngesrtvthfqytgwp..dhgvppslellleflelvreala

---EHGRVLVYCSNGYSRAVAVVMAYMM-----ATRSYNYDAALQLLQAIRPRIAPHDSFLKQLRDFQSF
   ..|.||| ||.| .|. ....||.|      .. .... |.. |.  || . . .|....|.|.  .
elpkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavqtpsqyrflydalle
0049772 (Phosphotyrosine protein) phosphatases II 365-481 2.3e-22 75.6 In-house 166-271 (314) alignment 
Range on Protein: 365-481
Range on HMM: 166-271/314.0
LArnrithvinvTETPFANGLPNL-VRCMQIPLLDgAHHDLLSVVPEALRFIEGCrREHGRVLVYCSNGYSRAV-AVVMAYMMATRSYNYDAALQLLQAI
|           .|.  .. ...| .. ..||. |  . .||. ..|.|.||| . ...|.||| |. | .|.  .||.||.|  . .... ||. ....
lk..........eelydpelferlgikylripvpD.gsaplledfdeflefieea.dkggpvlvHCkaGkgRtgtfvvaaylmkllgvsleealedvrlk

RPrIAPHDSFLKQLRDFQS
|| | |...|..||.... 
Rp.inpnpgfieqleqyef
subfamily_STYX_pd Subfamily STYX 365-487 2.6e-17 56.4 In-house 35-162 (166) alignment 
Range on Protein: 365-487
Range on HMM: 35-162/166.0
LARNRITHVINVTETPFANG----LPNLVRCMQIPLLDGAHHDLLSVVPEALRFIEGCRREHGRVLVYCSNGYSRAVAVVMAYMMATRSYNYDAALQLLQ
| .. |||.. . ... ||     .|.  | . . . | .  ...  .|.   ||... .. |.|||.   | ||. |.|.||.| |   .|  | . .|
lkkhgithivcirqnieanlikpnfpdrfrylvldvadntveniirylptvkefiddslqkggkvlvhgnagisrsaalviayimetyglkyreafayvq

AIRPRIAPHDSFLKQLRDFQS-FLSNAQ
  |  |.| . | .||..... .|.. .
errfcinpnegfvsqlkeyeaiylaklt
subfamily_Dicty-DSP19-like_pd Subfamily Dicty-DSP19-like 365-480 2.7e-17 56.5 In-house 24-149 (154) alignment 
Range on Protein: 365-480
Range on HMM: 24-149/154.0
LARNRITHVINV-T--ETPFANG-----LPNLVRCMQIPLLDGAHHDLLSVVPEALRFIEGCR--REHGRVLVYCSNGYSRAVAVVMAYMMATRSYNYDA
|  ..|....|| .  .  |..         ..  ... | | ...|..  .  |. ||.      |...|||.. .| ||. |....|.|  .. ..  
lqlkniksilnvgiGinnlftdensdindgfiieylnlelfddvnfdiiekldkafefiddaiggvennkvlvhsdkGvsrsaallisylmdklkislsl

ALQLLQAIRPRIAPHDSFLKQLRDFQ
||.||.  |. | |   |||||  |.
alellkdsryiikPnqGflkqleife
0040438 (Phosphotyrosine protein) phosphatases II 365-480 3.6e-15 51.5 In-house 106-272 (317) alignment 
Range on Protein: 365-480
Range on HMM: 106-272/317.0
LARNRITHVINVTETPFAN--------------------------GLPNLVRCMQIPLLDG----------------AHHDLLSVVPEALRFIEGCRRE-
. ....|.....||.   .                             . .   .... |                  .|.. .   . |.|.| .|.  
vweqgvtvivmLteleelgrekcaqYwplgetltygdftvtllseeelagitlrtlevedlgdsesrtvthfhytgWpdhgvppspdllldfleavreal

---HGRVLVYCSNGYSRAVAVVMAYMM-----ATRSYNYDAALQLLQAIRPRIAPHDSFLKQLRDFQ
   .| ||| ||.| .|. ....||.|      .. .... |.. |.. || . .  .....| |. 
edpggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrflydal
0043336 (Phosphotyrosine protein) phosphatases II 365-479 1.7e-12 42.9 In-house 108-272 (278) alignment 
Range on Protein: 365-479
Range on HMM: 108-272/278.0
LARNRITHVINVTETPFAN-----------------------------------------GLPNL-----VRCMQIPlLDGAHHDLLSVVPEALRFIEGC
.  ...|.....||    .                                         | ..      . .. .|  .|. ..| ...    ...| .
vwelgvttivmLtelvelgrvkcaqYwpggsltygdftvtllkeehlddytvrtlevtnlgdgesrtvthyhylgwp.dhgvpeslsllldflkavreal

RREHGRVLVYCSNGYSRAVAVVMAYMM-----ATRSYNYDAALQLLQAIRPRIAPHDSFLKQLRDF
. ..| ||| ||.| .|. .....|..      .. .... |.. |.  || . . .|....|...
edsngpvlVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqRpgavqtpsqyrflyea
0036941 (Phosphotyrosine protein) phosphatases II 369-483 1.5e-14 49.5 In-house 102-276 (297) alignment 
Range on Protein: 369-483
Range on HMM: 102-276/297.0
RITHVINVTETPFAN----------------------------------------------GLPNLVRCMQIPLLDGAHHDLLSVVPEALRFIEGCRR--
..|.....||    .                                              | ..  .....  ..  .|.. . . . |.||| .|.  
nvtvIvmltelvelgrekcaqywpleegesltygdftvtllsvevvllddytlrtlevtdtgngesrtvthfhytgwpdhgvpespaslldfielvrkvl

----EHGRVLVYCSNGYSRAVAVVMAYMM--------ATRSYNYDAALQLLQAIRPRIAPHDSFLKQLRDFQSFL
    ..|.||| ||.| .|. ....|..|         .. ...  |.. |   || . .  .....|...  .|
kllpsggpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyeallel
0038934 (Phosphotyrosine protein) phosphatases II 370-487 1.2e-13 46.7 In-house 57-180 (194) alignment 
Range on Protein: 370-487
Range on HMM: 57-180/194.0
ITHVINVTETPFANGLPN----LVRCMQIPLLDGAHHDLLSVVPEALRFIEGCRRE--HGRVLVYCSNGYSRAVAVVMAYMMATRSYNYDAALQLLQAIR
...||..|.| .           .. ...|  |  .   |... . |....   .|  .| |.| |  |..|.  .| ||.. .. .....|..|.. .|
lglvidltnteryYdpeefekagieylklpfpddgtvPsleillrfldlvdeflnedpggvvaVHCkaGlgRtGtlvaaYLiyrlgmsaeeAialfrekR

PRIAPHDSFLKQLRDFQSFLSNAQ
| . |. ..|..|. . ..| .|.
pgaipnqdyleallkrykelrkav
0051299 (Phosphotyrosine protein) phosphatases II 370-469 1.9e-08 29.6 In-house 163-271 (288) alignment 
Range on Protein: 370-469
Range on HMM: 163-271/288.0
ITHVINVTETPFANGLPNLVRCMQIPLLDGAHHDLLSVVPEALRFIEGCRRE----HGRVLVYCSNGYSRAVAVVMAYMM-----ATRSYNYDAALQLLQ
..... || . . .|  .  .....  ..  .|.  . . . |.|.. .|.     .| |.| ||.| .|. ........     ...  ..  |.. | 
tvrtlevtnldlldgdgesrtvthfhytnwpdhgvpdspellldflrlvrkalasgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlr

AIRPRIAPH
  || . . 
eqRpgmvqt
0047943 (Phosphotyrosine protein) phosphatases II 386-476 6.1e-10 34.5 In-house 163-264 (273) alignment 
Range on Protein: 386-476
Range on HMM: 163-264/273.0
PNLVRCMQIPLLDGAHHDLLSVVPEALRFIEGCRR------EHGRVLVYCSNGYSRAVAVVMAYMM-----ATRSYNYDAALQLLQAIRPRIAPHDSFLK
..   ....  ..   |.  . . . |.||| .|.      ..| |.| ||.| .|. ........     ...  ... |..||.  || . .  ....
gesrtvthfhytgwpdhgvppslesllefielvrkalealpsngpvvVHCsaGvgRtgtfialdllldqlekeggvdvleavkllrsqRpgmvqtpeqyr

QL
.|
fl
0050432 (Phosphotyrosine protein) phosphatases II 388-466 7.3e-08 27.6 In-house 196-281 (308) alignment 
Range on Protein: 388-466
Range on HMM: 196-281/308.0
LVRCMQIPLLDGAHHDLLSVVPEALRFIEGCRRE--HGRVLVYCSNGYSRAVAVVMAYMM-----ATRSYNYDAALQLLQAIRPRI
  .....  ..  .|.  . . . |.|.| .|.   .| ..| ||.| .|. ........     ...  ..  |.. |   ||  
srtvthfhytnWpdhgvPpspeilldflelvrkslpggpivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkklReqRpgm
subfamily_PTPMT1_pd Subfamily PTPMT1 389-483 5e-13 43.9 In-house 74-168 (171) alignment 
Range on Protein: 389-483
Range on HMM: 74-168/171.0
VRCMQIPLLDGAHHDLLSVVPEALRFIEGCRREHGRVLVYCSNGYSRAVAVVMAYMMATRSYNYDAALQLLQAIRPRIAPHDSFLKQLRDFQSFL
|  .|..  | ...  |  . ....|||  . .  || | |  | .|. ..| .|.| ..  . . ||. |...|. |  ..  .|.|. ....|
veqlqlatvDfteapdleklekgvefiekvaskgkrvYvHCkaGrgRsatlvacylmkkeklspeeAlkalkkkRkiirlakkqwkalqeyeekl
0046845 (Phosphotyrosine protein) phosphatases II 390-467 1.5e-07 26.6 In-house 166-257 (284) alignment 
Range on Protein: 390-467
Range on HMM: 166-257/284.0
RCMQIPLLDGAHHDLLSVVPEALRFIEGCRRE------HGRVLVYCSNGYSRAVAVVMAYMMATR--------SYNYDAALQLLQAIRPRIA
.....  ..  .|.  . .   |.|.. .|.       .| ..| ||.| .|. ........ ..         ...  |.. |   ||   
tvthfhytswpdhgvppspedlleflrlvrellenlpgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmv
subfamily_Sponge-DSP-Subfam1_pd Subfamily Sponge-DSP-Subfam1 397-483 2.2e-07 24.1 In-house 55-141 (145) alignment 
Range on Protein: 397-483
Range on HMM: 55-141/145.0
LDGAHHDLLSVVPEALRFIEGCRREHGRVLVYCSNGYSRAVAVVMAYMMATRSYNYDAALQLLQAIRPRIAPHDSFLKQLRDFQSFL
 |   .||     |   ||.  . |   |.|.|  | ||.|.| .|..|   .     | . ... | .  |   |||.| ...  |
edlesydlsqhfdevtdfidkgkeegagvfvhcmagvsrsvtvsvaflmkycnmtlseaarqvrsnrllaypnvtflknllnlekql
subfamily_MSG5_pd Subfamily MSG5 408-485 3.1e-07 23.7 In-house 85-162 (165) alignment 
Range on Protein: 408-485
Range on HMM: 85-162/165.0
VPEALRFIEGCRREHGRVLVYCSNGYSRAVAVVMAYMMATRSYNYDAALQLLQAIRPRIAPHDSFLKQLRDFQSFLSN
...  | |   . .. ..||.|  | ||. ....||.|   .     | ..|..    |.|   .. || ...  ||.
lsrltriihaatskrkkilvhcqcglsrsaslivayimkyynlslrdaydklksvaddispsiglifqlmewevalsk
0048567 (Phosphotyrosine protein) phosphatases II 411-476 1.8e-08 28.9 In-house 63-131 (157) alignment 
Range on Protein: 411-476
Range on HMM: 63-131/157.0
ALRFIEGCRREHGRVLVYCSNGY---SRAVAVVMAYMMATRSYNYDAALQLLQAIRPRIAPHDSFLKQL
. .|.. .. ..... |.|. |.   .|.. .. .|..   ... . |...|. .|| . |.      |
lnkflkilelagkaiavhckaglkkrgrtatLigcYlilhlgftpeeaiaplrivrpgsvpfrdasyll
subfamily_RNGTT_pd Subfamily RNGTT 420-478 2.3e-06 21.4 In-house 111-169 (189) alignment 
Range on Protein: 420-478
Range on HMM: 111-169/189.0
REHGRVLVYCSNGYSRAVAVVMAYMMATRSYNYDAALQLLQAIRPRIAPHDSFLKQLRD
. .  . |.|  |. |.  ....|.. ..... .||..| .  ||    .. .||.| .
npeevigvhCthGfnRtGFlivsyLvekedwsveaavalFakaRppGiykedylkellr
subfamily_PTPDC1_pd Subfamily PTPDC1 421-485 6.9e-06 20.6 In-house 113-177 (182) alignment 
Range on Protein: 421-485
Range on HMM: 113-177/182.0
EHGRVLVYCSNGYSRAVAVVMAYMMATRSYNYDAALQLLQAIRPRIAPHDSFLKQLRDFQSFLSN
..|.| |.|  |  |.  .. .|.. ..... . |..|... ||.     . .. ...|. ||..
qegkvavhChaGlGrtGvliacylvyakrltaekaiklvrskrpksiqtreqvelvkefalflip