Gene MbreMKP-Un-3 in Monosiga brevicollis

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family DSP
Subfamily DSP_MKP-unclassified
Protein sequence
ID Type Fasta BLAST phosphatome Note
MbreP004_AA protein Get Run
MbreP004_AA_280-427 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
Rhodanese Rhodanese-like domain 62-172 3.3e-07 22.8 Pfam-A 7-111 (113) alignment
Range on Protein: 62-172
Range on HMM: 7-111/113.0
SMLeaysPAHATLLLDTRHPSQFARHHIISSINMITAPLmmrrLGQGKVPLSAALRLDANDSAPDLEQITAIVLIGagdAANDQSVFDAVV-----AAVG
..|     .   .|||.| |...|. ||  ..|.    |     .... .    |  . ..|. .|.. . .|. .   .  ..| . | .      .  
ell....ekekvvllDvRspeeyakghIpgAvnvpldsl....yprrdlffkdklaeeleesgkkldkdktvvvyc...rsgnrsggaaalllalilkel

GHVVCYYLQGGFPSFA
|.  .|.| ||| ...
gyknvyvLdGGfeawk

0037934 (Phosphotyrosine protein) phosphatases II 278-421 4.5e-21 71.0 In-house 34-239 (243) alignment
Range on Protein: 278-421
Range on HMM: 34-239/243.0
AVESSLSDVWqGSIYIGCV--------HDATDRDLLTRTGITHVLSALEDC---------------------------------------------PE-V
 .  .|..|. . ......        ..|.. ..| . |||....  |..                                             .. .
yinanliyvt.prliatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqywpgevtygdftvtllseehlddytvrtlllenldlddlt

PMSIEQLHLPISDTFSSE-FEVLPSFLRGA-QFIHE-----AVSAGGRVLVHCAAGVSRSPTMVAAYLILYH-NMSMETSISHLQALRQV-VSPNLAFLG
 . |  ..||. |    . .| | .||. . .||.|     | . ||.||||| |||.|. |..||||.|.. ....|  . .|.. |   . ... .. 
rlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgRtGtliaaylmllllgvdleeavkllreqRpgkavqtpsqyr

VLLTMEQ
 |  ...
flyeall

0044763 (Phosphotyrosine protein) phosphatases II 281-422 7.5e-32 105.8 In-house 21-169 (178) alignment
Range on Protein: 281-422
Range on HMM: 21-169/178.0
SSLSDVWQGsIYIGCVHDATDRDLLTRTGITHVLSALED--------CPEVPMS--IEQLHLPISDTFSSEfeVLPSFLRGAQFIHEAV-SAGGRVLVHC
  .| .. | .|.|.  .| |..|| . ||||...  |.        .|. |..  |. ||.||.|    .  .|  ||.  .||.||. . ||.|||||
inaseilpg.lylgslppaddlellkelgithivnlteelelgflkcdpywpeeagiqylhipipDhgvpd..llehflefvefieealdekggpvlVHC

AAGVSRSPTMVAAYLILYHNMSMETSISHLQALRQvVSPNLAFLGVLLTMEQQ
 |||.||.|.|||||......|.|  |..... |  ..||  .|  |. .|..
saGvgRsgtlvaaylmkklglsleeaielvrerRp.ivpnpgqlrqLyefelr

subfamily_LRR-DSP_pd Subfamily LRR-DSP 281-421 3.8e-20 66.1 In-house 117-256 (263) alignment
Range on Protein: 281-421
Range on HMM: 117-256/263.0
SSLSDVWQGSIYIGCVHDATDRDLLTRTGITHVLSALEDC-PEVPMSIEQLHL-PISDTfsSEFEVLPSFLRGAQFIHEAVSAGGrVLVHCAAGVSRSPT
||. |     ...|. . |... .|   |.||.| |. |. |  |     | .  | |.   |...   | .   ||.|    || ||||| |||||| |
ssvPdeiidklflGgldsannksilkdlgvthillavadfePlfPklfkylsiddiedv..deadisqhfeetnafieeGrkkGG.vlvhcraGvsrsst

MVAAYLILYHNMSMETSISHLQALRQVVSPNLAFLGVLLTMEQ
.| .||. .... .. ..   .  |  . ||  |.  |.  |.
lvisylmkkqrlkfkealdlvikkrpriqPnpGfkdqlkkyek

subfamily_DSP3_pd Subfamily DSP3 282-423 4.6e-27 88.6 In-house 10-157 (162) alignment
Range on Protein: 282-423
Range on HMM: 10-157/162.0
SLSDVWQgSIYIGCVHDATDRDLLTRTGITHVLSALED-CPEV--------PMSIEQLHLPISDTFSSEFEVlpSFLRGAQFIHEAVSA-GGRVLVHCAA
.. .|.. ..|.|  . |.|.. |.. |||||| | |    .|         ..|. | |...|........   | . |.||.||.|   |.|||||..
evdevyp.klyvgdeavakdkskLkklGithvlnaaegrfskvdtgaefykdleikylGlevdDvpefdlsk..yFetaakfidealsqkegkvlvhcvv

GVSRSPTMVAAYLILYHNMSMETSISHLQALRQVvSPNLAFLGVLLTMEQQR
|||||.|.| |||.....|..   |.. .. |..  ||  ||  | ..... 
GvsRsatlvlayLmirrkmtlveairtvrkkRei.lPneGFlkqLaeldeel

0051082 (Phosphotyrosine protein) phosphatases II 283-413 1.1e-19 65.9 In-house 8-143 (151) alignment
Range on Protein: 283-413
Range on HMM: 8-143/151.0
LSDVWQGsIYIGCVHDATDRDLLTRTGITHVLSALE-----DCPEVPM--SIEQLHLPISDTFSSEfeVLPSFLRGAQFIHEAVSA-GGRVLVHCAAGVS
.|.|. | .|..    | . .|| . ||.....  .      |||     .|| ||.|| |.      .  ||   ..|.... .  .| ||||| ||..
fsyvtgg.lyrsggpladflellkelgiktivnlrseeergycpeylpelgievlhipildwpdpg..lplsfdavleflellldkkngpvlvHCsaGkg

RSPTMVAAYLILyHNMSMETSISHLQALRQ-VVSPNLAFL
|. |.||.||.| ...|.|. ...... |  || ||  ||
RTGtlvalylml.lgvsleealeeyrlkrpgvvqpnqqfl

subfamily_Choan-DSP_MKP-1_pd Subfamily Choan-DSP_MKP-1 284-422 6.8e-24 78.1 In-house 8-146 (148) alignment
Range on Protein: 284-422
Range on HMM: 8-146/148.0
SDVWQGSIYIGCVHDATDRDLLTRTGITHVLSALEDCPEV--PMSIEQLHLPISDtfSSEFEVLPSFLRGAQFIHEAVSAGGRVLVHCAAGVSRSPTMVA
|..... ...|  . |.| . |   |.|.. .| .... .    .|| ||....|    ....   |   ..|...|...|.|||||.  |||||  .. 
seikdafLFlGskksaadlealkalgvtrivnatkerdnaldqrgieYlhvaldD..kpkedlsaiFediiafvrkakdeGrrvLvhlqmGvsrssalal

AYLILYHNMSMETSISHLQALRQVVSPNLAFLGVLLTMEQQ
..|| ....|..  .   .  |. | ||| ||  |  .||.
lwlidfkrvslkealalvkskrryvdpnlgfLkqLaeleqa

subfamily_MKPLT_pd Subfamily MKPLT 285-421 6.8e-23 75.0 In-house 23-158 (164) alignment
Range on Protein: 285-421
Range on HMM: 23-158/164.0
DVWQGSIYIGCVHDATDRDLLTRTGITHVLSALEDCP-EVPMSIEQLHLPISDTfsSEFEVLPSFLRGAQFIHEAVSAGGRVLVHCAAGVSRSPTMVAAY
 | .  .| | ...||.. .|.   |||..   ...    |.|.| | . ..|.  |. .. . . | |.|. .|. .||||||||  |.||| ..  |.
vvledtlylGnakhatnekvlkdlkithivnvsqekkdafpksveYlqvkvede..sdeqlssfleraakfladaidsGGrvlvhcvqGksrsssvtvaf

LILYHNMSMETSISHLQALRQVVSPNLAFLGVLLTMEQ
||...   .. . ..|.  | .|.||  ||  | ..|.
LikskgwtlkeayeylkerrsivapnrGflkqlakfee

subfamily_MKPLV_pd Subfamily MKPLV 285-421 6.8e-23 75.0 In-house 23-158 (164) alignment
Range on Protein: 285-421
Range on HMM: 23-158/164.0
DVWQGSIYIGCVHDATDRDLLTRTGITHVLSALEDCP-EVPMSIEQLHLPISDTfsSEFEVLPSFLRGAQFIHEAVSAGGRVLVHCAAGVSRSPTMVAAY
 | .  .| | ...||.. .|.   |||..   ...    |.|.| | . ..|.  |. .. . . | |.|. .|. .||||||||  |.||| ..  |.
vvledtlylGnakhatnekvlkdlkithivnvsqekkdafpksveYlqvkvede..sdeqlssfleraakfladaidsGGrvlvhcvqGksrsssvtvaf

LILYHNMSMETSISHLQALRQVVSPNLAFLGVLLTMEQ
||...   .. . ..|.  | .|.||  ||  | ..|.
LikskgwtlkeayeylkerrsivapnrGflkqlakfee

0048179 (Phosphotyrosine protein) phosphatases II 286-421 5e-28 93.0 In-house 7-142 (144) alignment
Range on Protein: 286-421
Range on HMM: 7-142/144.0
VWQGsIYIGCVHDATDRDLLTRTGITHVLSALEDCPEVPM---SIEQLHLPISDTFSSefEVLPSFLRGAQFIHEAVSAGGRVLVHCAAGVSRSPTMVAA
...| .|.|.. .| | .|| . |||.|..  |...   .    |. ||||. |      . |  .|.  .||.||.. ||.||||| |||.|..|.|||
ilpg.lylgslptaldlellkklgittvinlteeyepefleregiqylhlpwpDhgvp..dllellleflefieealeeggpvlVHCsaGvgRtgtlvaa

YLILYHNMSMETSISHLQALRQVVSPNLAFLGVLLTMEQ
||......|.|  . .... |  . ||  .|  ||  |.
ylmkklglsleealalvrsrrpgavpnpgqlrfLleyek

0051429 (Phosphotyrosine protein) phosphatases II 286-440 1.5e-20 69.4 In-house 19-241 (272) alignment
Range on Protein: 286-440
Range on HMM: 19-241/272.0
VWQGSIYIGCVH---DATDRDLLTRTGITHVLSALE-------DCPEVPMSIEQLHLPISDTFSSEFEVL------------------------------
|. | .| .      .| | . | . ||.....  .       .|. ..  |. ||||| |.   . ...                              
vkpgrlyrsggplpltaadfwrlkelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseellldyilrellltlllsage

-------------------PSFLRGAQFIHEavsaGGRVLVHCAAGVSRSPTMVAAYLILyHNMS--------------METSISHLQALRQVVSPNLAF
                    ..|.  .....    ||.|||||.||..|. |.||..|.| ...|              .|  ...|.| |  . .. ..
arevmhlhytdwpdhgvpqeallellellld....ggpvlvHCsaGkdRTGtvvalllll.lgvsletivddYlltnlyleeaveelraqrpgavqteeq

LGVLLTMEQQRNDGRLSVDTTALTQHFD
.  |.  ...  .. |||.  .| ...|
ylflyeallellrsllsvraeyllaald

subfamily_STYXL1_pd Subfamily STYXL1 286-422 2.5e-16 53.3 In-house 14-152 (157) alignment
Range on Protein: 286-422
Range on HMM: 14-152/157.0
VWQGSIYIGCVHDATDRDLLTRTGITHVLSALEDCPEVPMSIE----QLHLPISDtfSSEFEVLPSFLRGAQFIHEAVSAGGRVLVHCAAGVSRSPTMVA
|  | .|.|  ..|... .     .  ..    |. ..  ...     ||....|  . | ..|. . .  |||.. .  |  |||    |.||| ....
vlPgklylGnykqaqnpaikkdlkvkahvnvsmdadkliagvadvakllhiaved..eneadllerlkeavqfiekhkkegevvlvfsnkGisrsaavii

AYLILYHNMSMETSISHLQALRQVVSPNLAFLGVLLTMEQQ
|||. ......... ..|.  .. | || ||.  |   |.|
aylmyskkitlkkaykylkkCkenvkPnrafveqlseWekq

0048076 (Phosphotyrosine protein) phosphatases II 287-422 1.8e-28 94.4 In-house 8-141 (145) alignment
Range on Protein: 287-422
Range on HMM: 8-141/145.0
WQGsIYIGCVHDATDRDLLTRTGITHVLSALEDCPEV-PMSIEQLHLPISDTFSSefEVLPSFLRGAQFIHEAVSAGGRVLVHCAAGVSRSPTMVAAYLI
..| .|.|....| |..|| . |||.||.   ... . .. |. |.||. |      . |  .|.  .||.||...||.||||| |||.|..|.|||||.
lpg.lylgslptaldlellkdlgittvlnltselellerlgiqylylpwpDhgvp..dllellleflefieealkeggpvlVHCsaGvgRtgtlvaaylm

LYHNMSMETSISHLQALRQVVSPNLAFLGVLLTMEQQ
|....|.|  . .... |  . ||  .|  |.  |..
lllgvsleealelvrsqrpgavpnpgqlrflyefele

PTEN_1 287-425 8e-23 76.3 In-house 44-193 (196) alignment
Range on Protein: 287-425
Range on HMM: 44-193/196.0
WQGSIYIGCVHDA-TDRDLLTRTGITHVLSALEDCPE----------VPMSIEQLHLPISDTFSSEFEVLPSFLrgAQFIHEAVS--AGGRVLVHCAAGV
. .. |.| ..|.  |.| |   |||.|..  |....            . .|.||.|| |   . .. |  ..  ..||. . |   |. |||||.||.
ideglyrgslkdvaadldnlkedgitlvvnlseeeelsgrsydleeffksgveylhfpieDhgapslselfdic..ksfiewllsdpngnvVlVHCkaGl

SRSPTMVAAYLILYHNMSMETSISHLQALRQVVSPNLAFLGVLLTMEQQRND
.|| |.|||||. .......  ...... | ...|| ...  ||  ......
gRsGtvvaayLmykgkltadeAlelvrekRppgapnspsqerlleyfaella

PTPc_motif_SM00404 289-421 3.6e-29 96.4 In-house 7-139 (140) alignment
Range on Protein: 289-421
Range on HMM: 7-139/140.0
GSIYIGCVHDATDRDLLTRTGITHVLSALEDCPE--VPMSIEQLHLPISDtfSSEFEVLPSFLRGAQFIHEAVSAGGRVLVHCAAGVSRSPTMVAAYLIL
. .|.|   .|....||.  |||||... | ..      ... |..|..|  . . .... . . ..||..| . ||.|||||.|||||| |...|||. 
phlylgskskaqnpallkklgithvinvteevsltkensgfqilqipldd..nekdklskyldkvldfienaekkggkvlVHCqaGvSRSatliiaYlmr

YHNMSMETSISHLQALRQVVSPNLAFLGVLLTMEQ
|...|.. ... ..  |. .|||| |.  |. .|.
yrqlslaeayefvkerRpiispnlnfvrqLieyek

subfamily_DSP14_pd Subfamily DSP14 289-427 2.6e-28 92.9 In-house 12-148 (157) alignment
Range on Protein: 289-427
Range on HMM: 12-148/157.0
GSIYIGcVHDATDRDLLTRTGITHVLSALEDCPEVPMS-IEQLHLPISDTfsSEFEVLPSFLRGAQFIHEAVSAGGRVLVHCAAGVSRSPTMVAAYLILY
 |....    |....||....||... .  . |. ... ||....|..|.  .| .. . | . |. |.|.  .||..||||.|||||| ... |||. |
psLfls.gvaalskellkkkkitliinvtvelpntklkdiervkvpveDn..peaklakhfdevadkieevkkkggktlvhCvaGvSRSAslclaylmky

HNMSMETSISHLQALRQVVSPNLAFLGVLLTMEQQRNDGR
...|.. . ..... | ...||. |   | . |.. ..  
eklsLreayklvksaRpiirPNvGFwkqlidyEkklkgks

subfamily_DSP19_pd Subfamily DSP19 289-423 9.9e-28 91.4 In-house 17-150 (152) alignment
Range on Protein: 289-423
Range on HMM: 17-150/152.0
GSIYIGCVHDATDRDLLTRTGITHVLSALEDCPEV-PMSIEQLHLPISDTfsSEFEVLPSFLRGAQFIHEAVSAGGRVLVHCAAGVSRSPTMVAAYLILY
 ..|.| .  |.|.. | ...|||.|.   . |.| |  .. |...| |.  .| ..|  . .  .||.|| |. |.||||| ||||||...| |||.  
prlylgsqdvaadkeilkekkitHilnvatgvpnvfpkdftylsieilDl..petdllsylkealdFieearskdgavlvHCnAGvSRsasvviaylmkk

HNMSMETSISHLQALRQVVSPNLAFLGVLLTMEQQR
...|.|.... ... |. ..||  |.  | ..|.. 
eelsleealelvrearpcikPneGFikqLkeyeael

0046846 (Phosphotyrosine protein) phosphatases II 289-422 7.2e-27 89.7 In-house 17-171 (176) alignment
Range on Protein: 289-422
Range on HMM: 17-171/176.0
GSIYIGCVH----------DATDRDLLTRTGITHVLSALED------------CPEVPMSIEQLHLPISDTFSSEFevlPSFLRGAQFIHEAVSAGGRVL
.....|.             |.. ..| . |||.|.. .|.              .  ..|. ||||. |    ..     .|.  .||.||...||.||
anlilgsrpiatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpeleklgiqylhlpwpDhgvpdl...elllellefirealkeggpvl

VHCAAGVSRSPTMVAAYLILY-HNMSMETSISHLQALRQ-VVSPNLAFLGVLLTMEQQ
||| ||..|..|.|||||. . ...|.|  ...... |   . .. ...  |  .|..
VHCsaGigRtgtlvaayllelekglsveealalvreqRplgavqtpeQyrflyefell

0041856 (Phosphotyrosine protein) phosphatases II 289-424 5.9e-26 86.6 In-house 24-173 (182) alignment
Range on Protein: 289-424
Range on HMM: 24-173/182.0
GSIYIGCVHD--------------ATDRDLLTRTGITHVLSALEDC----PEVPMSIEQLHLPISDTFSSEfevlpsFLRGAQFIHEAVSAGGRVLVHCA
 ..|.|. ..              | . ..| . |||..... |..     .  . |. |.||. |    .      .    .||.|. . ||.||||| 
anlylgslpatrfiatqgpllstvadflrmlkelgittivnlteelywpellerlgiqylylpwpDhgvpd......ldelldfieevleeggpvlVHCs

AGVSRSPTMVAAYLILYHNMSMETSISHLQALRQ--VVSPNLAFLGVLLTMEQQRN
|||.|..|.|||||......|.|  .....  |   |..||  |.  |. .| ...
aGvgRtgtlvaaylmkklgvsleeavklvrsrRpgmvitpnqyfflqlallellll

subfamily_DSP12_pd Subfamily DSP12 289-417 2e-25 84.0 In-house 7-137 (155) alignment
Range on Protein: 289-417
Range on HMM: 7-137/155.0
GSIYIGCVHDATDRDLLTRTGITHVLSALEDC----PEVPMSIEQLHLPISDTfsSEFEVLPSFLRGAQFIHEAVSAGGRVLVHCAAGVSRSPTMVAAYL
. .|.| ...... .||. ..||||||  .       . .  .......| |.   | ..|  . .  .||.||.. .| |||||.|||||| |.|.|||
pglylggleavqeeellkelkithvlsvikeelpehklkkgkvstkfiqilDe..peediLshldeavdFieealeeegavlvHCqagvSRSvtiviAYl

ILYHNMSMETSISHLQALRQVVSPNLAFLGVLL
. ....|.|. .. ... .. ..||  ||  | 
mkkeklslekAlklvkekkpeiepNegFleQLk

0045098 (Phosphotyrosine protein) phosphatases II 289-421 8.4e-24 79.8 In-house 27-269 (278) alignment
Range on Protein: 289-421
Range on HMM: 27-269/278.0
GSIYIGCVH-----------------------------------------DATDRDLLTRTGITHVLSALED----------------------------
 ..|.|...                                          | . ..|   |||..... |                             
palylgnldknRykdilpydhsrVkdYINAsyidgypkkfIatqgPlpstvadfwrmlwelgitvivmltelvelgrekcaqywpeggsltygdftvtll

----------------------CPEVPMSIEQLHL-PISDTFSSEFEVLPSFLRGAQFIHEAVS--------------AGGRVLVHCAAGVSRSPTMVAA
                          .. ...||. |. |  . ....| |||.  .||.||..               ||.||||| |||.|. |.|||
seevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllsslllldsggpvlVHCsaGvgRtGtlvaa

YLILYH---NMSMETSISHLQALRQV-VSPNLAFLGVLLTMEQ
||.|..   .....  ...|.  |   . .|| ..  |  ...
ylmlelleggvdlleavkelrsqRpglavqnleqyrflyefll

0042113 (Phosphotyrosine protein) phosphatases II 289-420 1.6e-17 59.2 In-house 52-239 (245) alignment
Range on Protein: 289-420
Range on HMM: 52-239/245.0
GSIYIGCVHDATDRD----LLTRTGITHVLSALE-----------------------------------------------DCPEVPMSIEQLHLPISDT
. ....    . . .    .| . |||....  |                                                ..|. . |  ..||. | 
pkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywplgesltygdftvtllseehlddytvrtlevtnlgddesrevihyhylpwpdh

FSSefEVLPSFLRGAQFIHEAVS--AGGRVLVHCAAGVSRSPTMVAAYLI-----LYHNMSMETSISHLQALRQVVSPNLAFLGVLLTME
     . | ..|.  .|...|..  ..|.||||| |||.|. |..||||.      ....|.|  . .|.  |  . ... ..  |  ..
gvp..dllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylmleqlekelgvsleeavkelrsqRpgavqtpsqyrflyeal

subfamily_DSP8_pd Subfamily DSP8 290-421 6.3e-29 94.6 In-house 21-152 (159) alignment
Range on Protein: 290-421
Range on HMM: 21-152/159.0
SIYIGCVHDATDRDLLTRTGITHVLSALEDCPEVPMSIE--QLHLPISDTFSSefEVLPSFLRGAQFIHEAVSAGGRVLVHCAAGVSRSPTMVAAYLILY
 .|.|. .|. ...||...||..|| | . ||.. .  |   |..|. |...   ..|| | .  .||  |.|. ||||||. || |||.|.. ||.. .
nlylGsqkdvlseellsklgisyvlnasnscpkleelkeskflrvPvkDkyde..kllpwfdksvefidkaksengrvlvhvlaGisrsatvaiayimkt

HNMSMETSISHLQALRQVVSPNLAFLGVLLTMEQ
 .||.. .  ...  |...|||| ||| ||  |.
lemsldeayrfvkekrptispnlnflgqLleyek

subfamily_DSP1_pd Subfamily DSP1 290-423 2.8e-28 93.0 In-house 24-156 (163) alignment
Range on Protein: 290-423
Range on HMM: 24-156/163.0
SIYIGCVHDATDRDLLTRTGITHVLSALEDCPEV-PMSIEQLHLPISDTFSSefEVLPSFLRGAQFIHEAVSAGGRVLVHCAAGVSRSPTMVAAYLILYH
 .|.|  ..|.....|...|||..| . .....| .   |  .|...|. .   ..   | .  .||.|. ...|.||.||.||.||| |.. |||.  .
fLylGsetvasnleiLkslgitailnvskeldnvfedlfeYkklkleDspka..dislvfeeviefidevkkknGkvlihCqaGisRsstlclaylmktk

NMSMETSISHLQALRQVVSPNLAFLGVLLTMEQQR
..|.|      .  |...|||..| . ||. |.. 
rvsleeafdfvkqrRsiisPnagFvlqLlnyekkl

subfamily_DSP6_pd Subfamily DSP6 290-422 3.7e-26 85.5 In-house 20-153 (158) alignment
Range on Protein: 290-422
Range on HMM: 20-153/158.0
SIYIGCVHDATDRDLLTRTGITHVLSALEDCPEVPMSIE---QLHLPISDTFSSEFEvlPSFLRGAQFIHEAVSAGGRVLVHCAAGVSRSPTMVAAYLIL
 .|.|. .||.....|.. .| .||   .. |..  . .    |..||.| .| ..     |    .|| || |.   ||||| ||.||| |.. |||. 
llylGsakdasnlevlkklkikyvlnvtsnlpnkfeesgelkylqipiedhlsqnla..kffPeaiefidearskkskvlvhClaGisrsvtvtlaylmk

YHNMSMETSISHLQALRQVVSPNLAFLGVLLTMEQQ
....|.. .   ... .  .|||. |.| ||  |..
klalslndaydlvkkrksnisPnfnfmgqlldfers

subfamily_DSP15_pd Subfamily DSP15 290-421 6e-26 85.4 In-house 8-137 (151) alignment
Range on Protein: 290-421
Range on HMM: 8-137/151.0
SIYIGCVHDATDRDLLTRTGITHVLSALEDCPEVPMSIEQLHLPISDTFSSEFEVlpSFLRGAQFIHEAVSAGGRVLVHCAAGVSRSPTMVAAYLILYHN
 .|.| ..|. |..||... |||.||  ..  ..   || . ...||| | ...    |    .|||.. . .. |||||.|||||| |.|.|||.   .
glylgnfrdskdeelLkeknithilsvhdnakkllkdieYkciaasDtpsaklsk..ffkesvefihkcRlkeenvlvhClaGvsRsvtlvvaYlmtvte

MSMETSISHLQALRQVVSPNLAFLGVLLTMEQ
.. . ... ..| |.|  ||. |   |   |.
lnwrdalevikaaRsvanPnfGfkrqlkeyek

0036282 (Phosphotyrosine protein) phosphatases II 290-422 1.2e-21 72.7 In-house 18-168 (174) alignment
Range on Protein: 290-422
Range on HMM: 18-168/174.0
SIYIGCVHDAtDRDLLTRTGITHVLSALEDCPE----------------VPMSIEQLHLPISDTFSSEFEVlpsFLRGAQFIHEAVSA--GGRVLVHCAA
 ...|..  | . ..| . |||.|.. || ..                 ... |. |.||. |    ....   .|.  .|..||.|   || ||||| |
rliagqgpla.fwemlkelgittvvmlleekelglykcinywpelredlerlgiqylylpwpDhgvpdlsi...llefvkfveealsedpggpvlVHCsa

GVSRSPTMVAAYLILYHNM-SMETSISHLQALR---QVVSPNLAFLGVLLTMEQQ
||.|..|.|||||.|.. . |..  ......||     . ..  ..  |  .|..
GvgRtGtlvaaylmlrglleslvdaldlvrelRlqrpgmvqtpsQyrflyyfekl

subfamily_Slingshot_pd Subfamily Slingshot 290-418 2.3e-19 63.4 In-house 25-152 (169) alignment
Range on Protein: 290-418
Range on HMM: 25-152/169.0
SIYIGCVHDATDRDLLTRTGITHVLSALEDCPEV-PMSIEQLHLPISDTFSSefEVLPSFLRGAQFIHEAVSAGGRVLVHCAAGVSRSPTMVAAYLILYH
 .|.|   .|.. . | ..|....|   ... .  | ..| |.. . |. ..  ..|. . .  .||..| ..| .|||||  ||||| . | || .  .
hvylGsewnasnleelkengveyilnvtkeidnffpekfeylnirvydeeet..dllkywnetykfiekakkkgskvlvhckmGvsrsastviayamkey

NMSMETSISHLQALRQVVSPNLAFLGVLLT
..|.|.......  |.|. || .||  | .
glsleealeyvkerrsvikPnkgflkqlee

subfamily_DSP10_pd Subfamily DSP10 291-424 3.8e-30 98.9 In-house 21-154 (159) alignment
Range on Protein: 291-424
Range on HMM: 21-154/159.0
IYIGCVHDATDRDLLTRTGITHVLSALEDCPEVPMS--IEQLHLPISDTFSSEfeVLPSFLRGAQFIHEAVSAGGRVLVHCAAGVSRSPTMVAAYLILYH
...|  .||.| |.| | .||.||    ..|       ..  ..|.||| . .  .   |    .||.|| . | |||||| ||.||| |.| |||. . 
LflGsekdaadldaldrlnitavlnvttsvPnefeeealkYkripvsDtskqn..lkqyfeealefieearkkgsrvLvhCqaGisrsatvviaYlmkhl

NMSMETSISHLQALRQVVSPNLAFLGVLLTMEQQRN
|.|.. .  . .  | ..||||.|.| || .|.. |
nlslndaykfvkekrpiisPnLnfmGqLlefekeln

DSPc Dual specificity phosphatase, catalytic domain 291-421 2.3e-28 93.7 Pfam-A 1-132 (133) alignment
Range on Protein: 291-421
Range on HMM: 1-132/133.0
IYIGCVHDATdRDLLTRTGITHVLSALEDCPE----VPMSIEQLHLPISDtfSSEFEVLPSFLRGAQFIHEAVSAGGRVLVHCAAGVSRSPTMVAAYLIL
.|.|   .|.  .||.  |||.|... . .|.     . .||.|..|. |  ..| .. . . .  .||..| . |..|||||.||.|||.|...|||. 
lylgskstas.lalleklgitlvinvtkevpnnnaikkseieylripved..etetkiskeleeavefiekaeqkgkkvlVHCqaGisRSatliiaYlmk

YHNMSMETSISHLQALRQVVSPNLAFLGVLLTMEQ
..|.|..  .....  |. .|||  ||. || .|.
tknlslneAyefvkerrskispnagflrqLleyer

DSPc Dual specificity phosphatase, catalytic domain 291-421 2.3e-28 93.7 In-house 1-132 (133) alignment
Range on Protein: 291-421
Range on HMM: 1-132/133.0
IYIGCVHDATdRDLLTRTGITHVLSALEDCPE----VPMSIEQLHLPISDtfSSEFEVLPSFLRGAQFIHEAVSAGGRVLVHCAAGVSRSPTMVAAYLIL
.|.|   .|.  .||.  |||.|... . .|.     . .||.|..|. |  ..| .. . . .  .||..| . |..|||||.||.|||.|...|||. 
lylgskstas.lalleklgitlvinvtkevpnnnaikkseieylripved..etetkiskeleeavefiekaeqkgkkvlVHCqaGisRSatliiaYlmk

YHNMSMETSISHLQALRQVVSPNLAFLGVLLTMEQ
..|.|..  .....  |. .|||  ||. || .|.
tknlslneAyefvkerrskispnagflrqLleyer

0049260 (Phosphotyrosine protein) phosphatases II 291-421 4.2e-24 80.4 In-house 15-147 (152) alignment
Range on Protein: 291-421
Range on HMM: 15-147/152.0
IYIGCVHDATDRDLLTRTGITHVLSALEDCPE----VPMSIEQLHLPISDTFSSEFEVLPSFLRGAQFIHeAVSAGGRVLVHCAAGVSRSPTMVAAYLIL
...|. . | . ..| . |||....  |...     ... |. ||||. |    ... |  ||  .  .. | . ||.||||| |||.|..|.|||||.|
qgpgpntladfwrmlkelgittivmltellelgklkceqyiqylhlpwpDhgvpdlsqlllflllfiekl.aldkggpvlVHCsaGvgRtgtlvaaylml

yHNMSMETSISHLQALRQVVSPNLAFLGVLLTMEQ
 ...|.|  ...... | .. ||  .|  |.  |.
.lgvsleeavalvrekRpgavpnpgqlrflyefek

0043147 (Phosphotyrosine protein) phosphatases II 292-423 1.8e-26 88.3 In-house 27-160 (172) alignment
Range on Protein: 292-423
Range on HMM: 27-160/172.0
YIGCVHDATDRDLLTRTGITHVLSALE----DCPEVPMSIEQLHLPISDTFSSefeVLPSFLRGAQFIHE--AVSAGGRVLVHCAAGVSRSPTMVAAYLI
. .. ..| ....| . ||||.... |      ..... |. |.||. |        |  .|.  .||.|  |.| ||.||||| |||.|..|.|||||.
gplrntladfwrmlkelgithivnltellydpellerlgiqylylpwpDhgvp...llellleflefidellalspggpvlVHCsaGvgRtgtlvaaylm

LyHNMSMETSISHLQALRQVVSPNLAFLGVLLTMEQQR
| ...|.|  ...... |  ...|  ..  |.  |...
l.lglsleeavalvrekRpgavqnpsqyrflyyfekll

subfamily_Sponge-DSP-Subfam1_pd Subfamily Sponge-DSP-Subfam1 292-423 6.4e-14 45.3 In-house 7-141 (145) alignment
Range on Protein: 292-423
Range on HMM: 7-141/145.0
YIGCVHDATDRDLLTRTGITHVLS-----ALEDCPEVPMSIEQLHLPISDTFSseFEVLPSFLRGAQFIHEAVSAGGRVLVHCAAGVSRSPTMVAAYLIL
|.| .  | |  .|.  ||. ..      ..        ||| | .  .|  |  ...   |   ..||      |  |.||| |||||| |.  |.|. 
yvgsalhandvptlqelgisrivnmaagslvasqelksesieillitaedles..ydlsqhfdevtdfidkgkeegagvfvhcmagvsrsvtvsvaflmk

YHNMSMETSISHLQALRQVVSPNLAFLGVLLTMEQQR
| ||..  .   ... |    ||. ||  || .|.| 
ycnmtlseaarqvrsnrllaypnvtflknllnlekql

subfamily_STYX_pd Subfamily STYX 292-418 1.4e-13 44.3 In-house 20-152 (166) alignment
Range on Protein: 292-418
Range on HMM: 20-152/166.0
YIGCVHDATD--RDLLTRTGITHVLSALED------CPEVPMSIEQLHLPISDTFSSefEVLPSFLRGAQFIHEAVSAGGRVLVHCAAGVSRSPTMVAAY
..|    |     . | . ||||..   ..       |. | ..  | | ..|.     ...  . .  .|| .... ||.||||  ||.||| ..| ||
flgpysaamksklevlkkhgithivcirqnieanlikpnfpdrfrylvldvadntve..niirylptvkefiddslqkggkvlvhgnagisrsaalviay

LILYHNMSMETSISHLQALRQVVSPNLAFLGVLLT
..  . .   ..  ..|  |  ..||  |   |  
imetyglkyreafayvqerrfcinpnegfvsqlke

0049772 (Phosphotyrosine protein) phosphatases II 296-422 6.7e-25 83.9 In-house 157-272 (314) alignment
Range on Protein: 296-422
Range on HMM: 157-272/314.0
VHDATDRDLLTrtgithvlSALEDCPEVPMS-IEQLHLPISDtFSSEfeVLPSFLRGAQFIHEAvSAGGRVLVHCAAGVSRSPT-MVAAYLILYHNMSME
  .| | .||         . | | . ..   |. |..|..| .|     |  |..  .||.|| ..||.|||||.||..|..| .|||||......|.|
eptaadlellk........eelydpelferlgikylripvpD.gsap..lledfdeflefieea.dkggpvlvHCkaGkgRtgtfvvaaylmkllgvsle

TSISHLQALRQvVSPNLAFLGVLLTMEQQ
. ...... |  ..||  |.  |. .|..
ealedvrlkRp.inpnpgfieqleqyefi

0040439 (Phosphotyrosine protein) phosphatases II 301-421 7.7e-20 67.0 In-house 70-243 (249) alignment
Range on Protein: 301-421
Range on HMM: 70-243/249.0
DRDLLTRTGITHVLSALEDCP--------------------------------------------EVPMSIEQLHLPISDTFssEFEVLPSFLRGAQFIH
....| . |||..... ....                                            . . |.. ||... |    .. | |||    .||.
fwrmlwelgitvivmLtslvelgrekcaqywplggsleygdftvtllsvevkddytvrtleltnlydgesrtvlhiqytdwp..dhgvppsfedlldfie

EAVS------AGGRVLVHCAAGVSRSPTMVAAYLI-----LYHNMSMETSISHLQALRQVVSPNLAFLGVLLTMEQ
.. .       ||.||||| |||.|..|..||||.      ......|  ...|.  |  . .|. ..  |. ...
avrkaleelpkggpvlVHCsaGvgRtGtfiaaylmleqlekelgvdleeavkllrsqRpgavqnpeqyrflyeall

0045450 (Phosphotyrosine protein) phosphatases II 304-420 8.3e-19 63.9 In-house 126-300 (307) alignment
Range on Protein: 304-420
Range on HMM: 126-300/307.0
LLTRTGITHVLSALEDCPE-----------------------------VPMSIEQLHLPISDT-FS--------------SEFEVLPSFLRGAQFIHEAV
.| . |.|....  |...                              .  ..  ..|...|. ..               .. | |||    .||.|. 
mlweqgvtvivmltelvelgrekcaqywPdegeeltygnftvtllseehldgytvrtlevtdldgtgesrtvthfhytgwpdhgvppsfeelldfieevr

S------AGGRVLVHCAAGVSRSPTMVAAYLILYHN--------MSMETSISHLQALRQVVSPNLAFLGVLLTME
.       ||.||||| |||.|..|..||||.|..         ....  ...|.. |  . .|. ..  |  ..
kaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrflyeal

subfamily_DSP23_pd Subfamily DSP23 304-403 3.1e-09 31.7 In-house 26-125 (148) alignment
Range on Protein: 304-403
Range on HMM: 26-125/148.0
LLTRTGITHVLSALEDCPEVPMSI---EQLHLPISDTFSSEFEVLPSFLrgaQFIHEAVSAGGRVLVHCAAGVSRSPTMVAAYLILYHNMSMETSISHLQ
 |   |. ...|  |...    ..      .| | |      | .  |.   . ..|| . .  | |||. |  |. ||.| ||.  ....   .|. ..
ylldlgvrylvslteegrphveatpnltlvrlriddyhppaleqvvefv...rvveeaeekneavsvhcllgrgrtgtmlacylvkerklaaaeaiaevr

ALR
 ||
rlr

0040438 (Phosphotyrosine protein) phosphatases II 307-420 1.5e-16 56.0 In-house 108-272 (317) alignment
Range on Protein: 307-420
Range on HMM: 108-272/317.0
RTGITHVLSALEDCPE----------------------------VPMSIEQLHLPISDTFS--------------SEFEVLPSFLRGAQFIHEAVSA---
. |.|....  | ..                             .  .|. ..|...|. .               .. | ||.    .|.... .|   
eqgvtvivmLteleelgrekcaqYwplgetltygdftvtllseeelagitlrtlevedlgdsesrtvthfhytgWpdhgvppspdllldfleavrealed

-GGRVLVHCAAGVSRSPTMVAAYLI-----LYHNMSMETSISHLQALRQVVSPNLAFLGVLLTME
 || ||||| |||.|. |..||||.      ......|  . .|.. |  . ......  | ...
pggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrflydal

subfamily_Dicty-DSP19-like_pd Subfamily Dicty-DSP19-like 324-423 1.5e-14 47.6 In-house 53-152 (154) alignment
Range on Protein: 324-423
Range on HMM: 53-152/154.0
PMSIEQLHLPISDTfsSEFEVLPSFLRGAQFIHEAV--SAGGRVLVHCAAGVSRSPTMVAAYLILYHNMSMETSISHLQALRQVVSPNLAFLGVLLTMEQ
 . || |.| . |    .|... .. .  .||..|.     ..||||. .||||| ... .||.   ..|.  ..  |.  | ...||  ||  |  .|.
gfiieylnlelfdd..vnfdiiekldkafefiddaiggvennkvlvhsdkGvsrsaallisylmdklkislslalellkdsryiikPnqGflkqleifek

QR
..
el

0038934 (Phosphotyrosine protein) phosphatases II 325-425 6.3e-19 63.8 In-house 78-178 (194) alignment
Range on Protein: 325-425
Range on HMM: 78-178/194.0
MSIEQLHLPISDT-FSSEFEVLPSFLRGAQFIHEAvSAGGRVLVHCAAGVSRSPTMVAAYLILYHNMSMETSISHLQALRQVVSPNLAFLGVLLTMEQQR
. || |.||. |  ..  .|.| .||. ....... ..|| |.||| ||..|..|.|||||| ...||.| .| ...  |. . ||  .| .||.  .. 
agieylklpfpddgtvPsleillrfldlvdeflne.dpggvvaVHCkaGlgRtGtlvaaYLiyrlgmsaeeAialfrekRpgaipnqdyleallkrykel

ND
..
rk

subfamily_PTPMT1_pd Subfamily PTPMT1 326-407 5.5e-16 53.5 In-house 73-152 (171) alignment
Range on Protein: 326-407
Range on HMM: 73-152/171.0
SIEQLHLPISDTF-SSEFEVLpsfLRGAQFIHEAVSAGGRVLVHCAAGVSRSPTMVAAYLILYHNMSMETSISHLQALRQVVS
 .|||.|.. | . . ..| |   ..| .||..  | | || ||| || .|| |.||.||.. ...|.|. ...|.. |. . 
gveqlqlatvDfteapdlekl...ekgvefiekvaskgkrvYvHCkaGrgRsatlvacylmkkeklspeeAlkalkkkRkiir

subfamily_Laforin_pd Subfamily Laforin 330-399 1.2e-06 21.6 In-house 80-147 (183) alignment
Range on Protein: 330-399
Range on HMM: 80-147/183.0
LHLPISDTF-SSEFEVLPsflRGAQFIHEAVSAGGRVLVHCAAGVSRSPTMVAAYLILYHNMSMETSISHL
. ||. |    |  | ||   ..  ..|  .  | .| ||| ||| || ..|  .|    . |.     .|
iwlptedlstesrvenlp...qavyllhallekghivyvhcnagvgrstaivcgflqyvlgwslakvqyfl

subfamily_PTEN_pd Subfamily PTEN 331-394 1.7e-06 23.2 In-house 84-146 (184) alignment
Range on Protein: 331-394
Range on HMM: 84-146/184.0
HLPISDTFSSEFEVLPSFLRGAQFIHEAvSAGGRVLVHCAAGVSRSPTMVAAYLILYHNMSMET
..|..| .. ..|.| .... ..   |. .    | ||| ||  |. ....|||. .. .. ..
vypfdDhnppplelleeivediekwlee.dkknvvvvHCkaGkGRtGvlivayllkslllekae

0047943 (Phosphotyrosine protein) phosphatases II 334-414 1.6e-12 42.9 In-house 176-262 (273) alignment
Range on Protein: 334-414
Range on HMM: 176-262/273.0
ISDTFSS-EFEVLPSFLRGAQFIHEAVSAGGRVLVHCAAGVSRSPTMVAAYLI-----LYHNMSMETSISHLQALRQVVSPNLAFLG
. |      .| | .|.. .. ..||.  .| |.||| |||.|. |..|..|.      .......  . .|.  |  . ... .. 
wpdhgvppslesllefielvrkalealpsngpvvVHCsaGvgRtgtfialdllldqlekeggvdvleavkllrsqRpgmvqtpeqyr

0046845 (Phosphotyrosine protein) phosphatases II 336-405 2.1e-11 39.2 In-house 178-255 (284) alignment
Range on Protein: 336-405
Range on HMM: 178-255/284.0
DTFSSEFEVLPSFLRGAQFIHEAVSAGGRVLVHCAAGVSRSPTMVAAYLILYH--------NMSMETSISHLQALRQV
.   ...| | .||| .. ..|... || ..||| |||.|. |..|..|.|..        .....  ...|   |  
hgvppspedlleflrlvrellenlpgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpg

0036941 (Phosphotyrosine protein) phosphatases II 339-420 2.7e-14 48.6 In-house 178-273 (297) alignment
Range on Protein: 339-420
Range on HMM: 178-273/297.0
SSEFEVLPSFLRGAQFIHEAVS------AGGRVLVHCAAGVSRSPTMVAAYLI--------LYHNMSMETSISHLQALRQVVSPNLAFLGVLLTME
  .. | .|.    .||... .       ||.||||| |||.|| |..||.|.         ......   . .|   |  . ..| ..  |  ..
wpdhgvpespaslldfielvrkvlkllpsggpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyeal

0051299 (Phosphotyrosine protein) phosphatases II 341-407 2.4e-10 35.8 In-house 194-269 (288) alignment
Range on Protein: 341-407
Range on HMM: 194-269/288.0
EFEVLPSFLRGAQFIHEAVSA----GGRVLVHCAAGVSRSPTMVAAYLI-----LYHNMSMETSISHLQALRQVVS
.. | .|.    .|.... .|    || |.||| |||.|. |..|..|.       . ....  . .|   |  . 
dhgvpdspellldflrlvrkalasgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlreqRpgmv

0039614 (Phosphotyrosine protein) phosphatases II 342-421 9.3e-16 53.6 In-house 202-286 (297) alignment
Range on Protein: 342-421
Range on HMM: 202-286/297.0
FEVLPSFLRGAQFIHEAVSAGGRVLVHCAAGVSRSPTMVAAYLI-----LYHNMSMETSISHLQALRQVVSPNLAFLGVLLTMEQ
.|.| .||. .. .... . ||.||||| |||.|. |..||||.      .......  ...|.  |  . ... ..  |  ...
lellleflelvrealaelpkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavqtpsqyrflydall

0050432 (Phosphotyrosine protein) phosphatases II 342-405 1.7e-09 32.9 In-house 210-280 (308) alignment
Range on Protein: 342-405
Range on HMM: 210-280/308.0
FEVLPSFLRGAQFIHEAVSA--GGRVLVHCAAGVSRSPTMVAAYLI-----LYHNMSMETSISHLQALRQV
. | ||.    .|.... .   || ..||| |||.|. |..|..|.       ......  . .|   |  
hgvPpspeilldflelvrkslpggpivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkklReqRpg

0043336 (Phosphotyrosine protein) phosphatases II 346-417 7.5e-13 44.0 In-house 193-270 (278) alignment
Range on Protein: 346-417
Range on HMM: 193-270/278.0
PSFLRGAQFIHEAVS-AGGRVLVHCAAGVSRSPTMVAAYLI-----LYHNMSMETSISHLQALRQVVSPNLAFLGVLL
 ..|.  ....||..  .| ||||| |||.|. |..|.||.      ......|  ...|.  |    ... ..  | 
sllldflkavrealedsngpvlVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqRpgavqtpsqyrfly

subfamily_MSG5_pd Subfamily MSG5 350-418 2.1e-14 47.0 In-house 87-155 (165) alignment
Range on Protein: 350-418
Range on HMM: 87-155/165.0
RGAQFIHEAVSAGGRVLVHCAAGVSRSPTMVAAYLILYHNMSMETSISHLQALRQVVSPNLAFLGVLLT
| .. || | | . ..||||  |.||| ... ||.. |.|.|.. .  .|..  . .||.. ..  |. 
rltriihaatskrkkilvhcqcglsrsaslivayimkyynlslrdaydklksvaddispsiglifqlme

subfamily_CDC14_pd Subfamily CDC14 353-412 2.3e-07 25.0 In-house 254-315 (328) alignment
Range on Protein: 353-412
Range on HMM: 254-315/328.0
QFIHEAVSAGGRVLVHCAAGVSRSPTMVAAYLILYHNMSMETSISHLQALR--QVVSPNLAF
.|.. | .| | . ||| ||. |  |..|.||.  .... . .|..|.  |  .|..|   |
kfleiaekaeGaiavhCkaGLGrtGtLiacylmkhyrftaaeaiawlricrPGsvigpqqkf

subfamily_PTPDC1_pd Subfamily PTPDC1 354-403 7.5e-07 23.8 In-house 107-155 (182) alignment
Range on Protein: 354-403
Range on HMM: 107-155/182.0
FIHEAVSAGgRVLVHCAAGVSRSPTMVAAYLILYHNMSMETSISHLQALR
 .. |.. | .| ||| ||  |   ..|.||.  .... | .|. ... |
vvafalqeg.kvavhChaGlGrtGvliacylvyakrltaekaiklvrskr

0048567 (Phosphotyrosine protein) phosphatases II 355-404 6.3e-09 30.4 In-house 67-119 (157) alignment
Range on Protein: 355-404
Range on HMM: 67-119/157.0
IHEAVSAGGRVLVHCAAGV---SRSPTMVAAYLILYHNMSMETSISHLQALRQ
..    ||... ||| ||    .|. |....||||..... |  | .|.  |.
lkilelagkaiavhckaglkkrgrtatLigcYlilhlgftpeeaiaplrivrp

PTPc_DSPc_SM00012 357-405 7.9e-09 31.0 In-house 31-82 (105) alignment
Range on Protein: 357-405
Range on HMM: 31-82/105.0
E------AvsaGGRVLVHCAAGVSRSPTMVAAYLILYHNMSMETSISHLQALRQV
.          .. |.||| |||.|. |.||....| .... ..... .| ....
knknkses...skpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkel