Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
| Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
|---|---|---|---|---|---|---|---|---|---|
| SH2 | SH2 domain | 129-202 | 1.4e-09 | 28.5 | Pfam-A | 1-75 (77) | alignment | ||
Range on Protein: 129-202
Range on HMM: 1-75/77.0
WYVGKISAAEAKIMLDT-EPCGAWLVRASA-EEHAYSLMVKDMRgDINNFLLTEEPKDGGICLGTSRFDRVDDLIR
||.|||| .||. .|.. .. |..||| | .. |.| |.| . ..... .. . . .. . .|. ...|..
WyhgkisreeaerlLlegkkdGtFLvReSeskpGdytlsvvddg.kvkhyriqslengkyyitenekfsslqeLve
|
|||||||||
| SH2 | SH2 domain | 417-491 | 3.9e-07 | 20.7 | Pfam-A | 1-75 (77) | alignment | ||
Range on Protein: 417-491
Range on HMM: 1-75/77.0
WYAGRVSRQAAAAVILQspNVRPGDFFFHQHPLEENVFYLTVNDHDRAAQYKIARNSAG--YVFGPKTFLTLQRLLE
|| | .||. | .|. . ..|.| . ... . |.| | .. .|.| .. | |... ..| .|| |.|
WyhgkisreeaerlLle..gkkdGtFLvReSeskpGdytlsvvddgkvkhyriqslengkyyitenekfsslqeLve
|
|||||||||
| 0040438 | (Phosphotyrosine protein) phosphatases II | 713-1008 | 1.3e-64 | 213.8 | In-house | 21-284 (317) | alignment | ||
Range on Protein: 713-1008
Range on HMM: 21-284/317.0
IQGYKELPRGETHESDLPDYARGPRLNRFRDILPNPVTRVRLEPLEVDHTLEYINANYVRdpsapcdnkpallgfGGRRAKEYVAAQAPKDTGLFNFWRM
.....|.. .. . . . .||..||||.. .||.| ||. |. . ||||.|| | .. ....|.|.|.. ...||||
leefedllslkldtysvaelpenkdknrypdilpydhsRVkLsplggdldsdYInAsyvd...............gpnlkrkfIatqgPlpntvedFwrm
IVHVQARCIAMTTGLVEGGKNKCSRYWPAtiyaetKEELVYgprdGKIHVRTMLVTKMEGYIKTNIQVL--YQGSTRNLVHFWFTAWPDHGVPTrpdgsm
. . . ..| | | |.| |..|| .||| .|.|.| |...|... .....|.. ....| . . .| . ||..|.|||||||
vweqgvtvivmLteleelgrekcaqYwpl......getlty....gdftvtllseeelagitlrtlevedlgdsesrtvthfhytgWpdhgvpp......
QTQQMIEMLLDIRRTRNeldRAESPLIVHCSAGIGRTGTMIALDHAMCALDMGVKVDVLSIVADIREDRMAMVQHVVQYRYLYQAVVEYAERLAAREQ
.......| .|. .. . ..|..||||||.|||||.||.. ... |. . .||| ..|. .|| |. .|| |||.||.|. || | .|
spdllldfleavreale...dpggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrflydalleylkrkltlep
|
|||||||||
| 0043336 | (Phosphotyrosine protein) phosphatases II | 714-999 | 5.4e-62 | 205.1 | In-house | 24-276 (278) | alignment | ||
Range on Protein: 714-999
Range on HMM: 24-276/278.0
QGYKELPRGETHESDLPDYARGPRLNRFRDILPNPVTRVRLEPLEVDHTLEYINANYVRdpsapcdnkpallgfGGRRAKEYVAAQAPKDTGLFNFWRMI
....||.. . . . . .||..||||.. .||.|..|. | . ||||.|| | .. ....|.|.| . . .||||.
lefeellsfkldtysiallpenkdknrykdilpydhsrvklsllggdldsdYinAsyvd...............gynvprkfiatqgPlpetvedFwrmv
VHVQARCIAMTTGLVEGGKNKCSRYWPatiyaetKEELVYGPrdgkIHVRTMLVTKMEGYIKTNIQVL--YQGSTRNLVHFWFTAWPDHGVPTrpdgsmQ
. . ..| | |.||| |..|| .||| .. |.||. ..|... ......|. ... | . | .| .|.....|||||||. .
welgvttivmLtelvelgrvkcaqYwp.......ggsltygd....ftvtllkeehlddytvrtlevtnlgdgesrtvthyhylgwpdhgvpe......s
TQQMIEMLLDIRRTRNeldRAESPLIVHCSAGIGRTGTMIALDHAMCALDMGVKVDVLSIVADIREDRMAMVQHVVQYRYLYQAVVEY
.......| ..|. .. ..|..||||||.|||||.|||. ... |. . .||....|...|| |. .|| |||.||.|. ||
lsllldflkavreale...dsngpvlVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqRpgavqtpsqyrflyealley
|
|||||||||
| subfamily_PTPRD_pd | Subfamily PTPRD | 714-1020 | 1.5e-60 | 200.5 | In-house | 27-301 (564) | alignment | ||
Range on Protein: 714-1020
Range on HMM: 27-301/564.0
QGYKELPRGETHESDLPDYARGPRLNRFRDILPNPVTRVRLEPLEVDHTLEYINANYVRdpsapcdnkpallGFGgrRAKEYVAAQAPKDTGLFNFWRMI
. ||.. .|.... . .. . ||. .|.. .||.|...| |. .||||... |. . |.|.|.|.|. . . .||||.
eeykkieegqqftweaankpaNkaKNRyanivaYdhsRVvLskvegdegsDYINAsfid.............gyr..krkayIAtqgPlaetiedFWRmv
VHVQARCIAMTTGLVEGGKNKCSRYWPAT---IYAETKEELVYGPRDGKIHVRTMLVTKMEgyiktniqvlyQGSTRNLVHFWFTAWPDHGVPTRPdgsm
. ..| | | |.| ||.||..|||.. | | . .|. . ....||. ..| . . ..|. .| ||.|||||||. .
weqnsstiVmltkleEkgkvkchkYWPekgtetygeltVtleeeeeladyeirtfklkkkk...........ssesreVrqFhFtsWPdhgvpesa....
qtQQMIEMLLDIRRTRNeldRAESPLIVHCSAGIGRTGTMIALDHAMCALDMGVKVDVLSIVADIREDRMAMVQHVVQYRYLYQAVVEYAERLAAREQEE
....... ..|.... . . |..||||||.||||| |..| . . .||. ..|. .|..| |||| || ....|..|. . . |
..tslLdlirkvralne...pdagPivVhCSaGVGRTGtfividamlerikeektvDiyqyvkalrkqRnamVqteeQYiFiheailealacgntevese
EAAQAYEQMR
. |. ....
nlkqhlqkLa
|
|||||||||
| subfamily_Ptp69D_pd | Subfamily Ptp69D | 714-1018 | 3e-47 | 156.2 | In-house | 26-304 (307) | alignment | ||
Range on Protein: 714-1018
Range on HMM: 26-304/307.0
QGYKELPRGET-HESDLPDYARGPRLNRFRDILPNPVTRVRLEPLEVDHTLEYINANYVRdpsapcdnkpallGFggRRAKEYVAAQAPKDTGLFNFWRM
. |..|.. |. ... . ||. || . |||.|.... ... .||||.... |. . |...|||.| .. ...||||
keyekLeareidkstkvsekkenalknRyedikafDktRvkLkkingkedsdYinasfik.............gy..kekkkfiaaqdPveatigDfWRm
IVHVQARCIAMTTGLVEGGKNKCSRYWPATiyaetkEELVYGprdgKIHVRTMLVTKMEGYIKTNIQVLYQG-------STRNLVHFWFTAWPDHGVPTR
| . | | . | | ..||..||| .| || .| |... |.. ||. ...| .. .|..| . .|.|.| ||
iaeqevtlivmlsnlteknrkkcakYWpie......devqyg....dilvklvseekhsdyiiReldvskkkeesgevedsrkvvqyhytgWkDskvPev
PDGSMQtqqMIEMLLDIRRTRneldraESPLIVHCSAGIGRTGTMIALDHAMCALDMGVKVDVLSIVADIREDRMAMVQHVVQYRYLYQAVVEYAERLAA
. | .. .||.. .. .. .||..|||||| ||.|...||| . | |||. .| |.|..| .|| || .||.|...| . .
argllk...lieqvrelykln......rsPivvhCsaGvgrsgifvaldsllqqlkaedkvdifetvkdLrsqRnllvqsleqYvflyralldyssygdt
REQEEEAAQAYEQ
|. .. ..|.|.
dedvddledaier
|
|||||||||
| subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 714-998 | 6.6e-41 | 135.2 | In-house | 28-277 (315) | alignment | ||
Range on Protein: 714-998
Range on HMM: 28-277/315.0
QGYKELPRGETHESDLPDYARGPRLNRFRDILPNPVTRVRLEPLEVDHTLEYINANYVRdpsapcdnkpallgfGGRRAKEYVAAQAPKDTGLFNFWRMI
| |. .| |. | | . ||. .|.. .||.| ||.| .|.|||.. | . . |.|||.|. . . .|||..
qdyesipggqlhpldvakkienkqknryiniiaydksrvqlpllendphsdyvnanfid...............Gynkkrryiaaqgpnvasvkdfwrlv
VHVQARCIAMTTGLVEGGKNKCSRYWPATiyaetkeELVYGprdgKIHVRTMLVTKMEGYIKTNIQVLYQGSTRNLVHFWFTAWPDHGVPTrpdgsmQTQ
. . | | |.|||| |.|. .||| ...|| || | . . . | . | .. |..| . .|.||| ||| |
feedigkivmltnlvegekrkaekywpdk.......kviyG....kitvtrkseevnteytvrtlsvvfgdnirevvqlhytswpdmgvpk......yti
QMIEMlldIRRTRNELDRAESPLIVHCSAGIGRTGTMIALDHAMCALDMGVKVDVLSIVADIREDRMAMVQHVVQYRYLYQAVVE
.... ||. . . . ....||||||.|||||.|.|| . ... .|| .. .|. |. ||| . ||...|.|..|
plmnl...irtvkqhhtnsvgaivvhcsaGvGrtGtfitldavldqaeaenaidvynfitgvrqnrikmvqvaeqyqfiydalle
|
|||||||||
| subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 716-1005 | 5.2e-124 | 407.6 | In-house | 1-269 (270) | alignment | ||
Range on Protein: 716-1005
Range on HMM: 1-269/270.0
YKELPRGETHESDLPDYARGPRLNRFRDILPNPVTRVRLEPLEVDHTLEYINANYVRdpsapcdnkpallGFGGRRAKeYVAAQAPKDTGLFNFWRMIVH
.|||...||.|||||..|||..|||..||||.|.||||||.|| |.. .|||||||| || |...| |.||..|..|.|..|||||..
fkeldkeetsesdlpeaargkklnRyadiLPsPatRvrleeleedsataYinAnyvr.............Gfdgekkk.YiaamgPlpttlksfwrmiwe
VQARCIAMTTGLVEGGKNKCSRYWPAtiyaETKEELVYgpRDGKIHVRTMLVTKMEGYIKTNIQVLYQGSTRNLVHFWFTAWPDHGVPTRPDGSMQTQQM
.....|.|||||.| |..||.||||| |.||.. . .||||.|... .|.||||.|.... ..|..|.|||||...|||||||...|.|..|.|.
ekvtaivmttgleEkgrkkCerYWpa....epkekvkl..edgkikvlalseekeegyiltrlrleekgeerrlvHfwyntWpdhgvpreedsslstdql
IEMLLDIRRTRNELDRAEsPLIVHCSAGIGRTGTMIALDHAMCALDMGVKVDVLSIVADIREDRMAMVQHVVQYRYLYQAVVEYAERLAA
..|| ..||...|||.|| ||.||||||.|||||.||||.|...|.. .|||||.|....|.||||.|||..||..||.||||||||.|.
lkmlravrrsekeldkae.PllvHcsaGvgRtGtlialDiavrlLeetkkvdvlaiieelRkdRmalvqhpeqyeflykavveyaerrak
|
|||||||||
| subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 716-1001 | 2.7e-55 | 182.5 | In-house | 27-280 (288) | alignment | ||
Range on Protein: 716-1001
Range on HMM: 27-280/288.0
YKEL-PRGETHESDLPDYARGPRLNRFRDILPNPVTRVRLEPLEVDHTLEYINANYVRDpsapcdNkpallgfggRRAKEYVAAQAPKDTGLFNFWRMIV
|. | . ..|.... |. . ||.|.||| .||.|. || .. .||||.|. . . .. |.|.|.|.| . .||...
ynsLaalektksvtagrlavnakknRyrnilpyDekrvklkkleeeagaDYinasyidg......e.........kkkkkyiatqgPladtvndfWelvy
HVQARCIAMTTGLVEGGKNKCSRYWPATiyaetKEELVYgprdGKIHVRTMLVTKMEGYIKTNIQVLYQGSTRNLVHFWFTAWPDHGVPTrpdgsmQTQQ
.. |.| |.||||||.|| .|||.. ... | |.. | . . ..| ... .. . ... ... .. ..|||||||| ....
enktstivmltelveggktkCeeYWPda.....dkpkny....GsvtvtlveskeledfvlrklllekkkteleitqyqylaWpdhgvPe......skap
MIEMLLDIRRTRNELdraESPLIVHCSAGIGRTGTMIALDHAMCALDMGVKVDVLSIVADIREDRMAMVQHVVQYRYLYQAVVEYAE
..|.| . . .. |.|||||||.||||| |||| .. |.. ..||...|| .|. |. .|| . || ..|..... .|
llellrqvkvanqad...tgpiivhCsaGvGrtgtFialdalidaveeedyiDvagtvaklRkqRallvqtlkqYefiyevllslie
|
|||||||||
| subfamily_Sponge-PTP9_pd | Subfamily Sponge-PTP9 | 716-999 | 1.5e-31 | 104.2 | In-house | 21-292 (301) | alignment | ||
Range on Protein: 716-999
Range on HMM: 21-292/301.0
YKELPRGETHESDLPDYARGPRLNRFRDILPNPVTRVRLEPLEV--DHTLEYINANYVRdpsapcdnkpallgfGGRRAKEYVAAQAPKDTGLFNFWRMI
|||| .|| ..... . .||||..| . . |. |.| . .. |||||.|. | ...|...|||.| . | .|||.|
ykelkegedksctvglseenkalnrfknitvyddnriilkpkpnldlcqreyinasyid...............gysekkkfiaaqgpmkktlvdfWrli
VHVQARCIAMTTGLVEGGKNKCSRYWPATIYAETKEELVYGPRDG-----KIHVRTMLVTKM----EGYIKTNIQVLYQGSTRNLVHFWFTAWPDHGVPT
.. . | | |.| || |.|| .||| . .... . .| . |. .|||. ...| . |..... . | ||..||
wqekpvsivmvtnlkegtkskceqywpnseaeseefgpftvtlvneqvyPdfvirqlnvkiqdgsnngyierkfkvksdksswdvlqlqvtdWpqdGvvr
RPDGSMQTqqmIEMLldIRRTRNeldRAESPLIVHCSAGIGRTGTMIALDHAMCALDMGVKVDVLSIVADIREDRMAMVQHVVQYRYLYQAVVEY
| .| |. | |.. .|..||||....|.|. .... .. ||| .. .| .. .|. || .|... .|
eprtvLqv...iddv..ihrqqk...igggpvvVHCSdtVsrsGvYcsvsiglEQckaegVVdvfqvtkavrrskpgaVtTLeqytsiydvidmy
|
|||||||||
| subfamily_Cele-PTP-8_pd | Subfamily Cele-PTP-8 | 716-999 | 5.6e-25 | 83.0 | In-house | 25-270 (288) | alignment | ||
Range on Protein: 716-999
Range on HMM: 25-270/288.0
YKELPRGEThESDLPDYARGPRLNRFRDILPNPVTRVRLEplevDHTLEYINANYVRdpsapcdnkpallgfGGRRAKEYVAAQAPKDTGLFNFWRMIVH
|.. | . . . . | .|.... .|||.|. | . ||.|| | .. . . |||| .. . ..|.|...
yrdspneas.idiidsfianptrdryenlprcditrvkls....ddpdfyiaanvvs...............sakykrrlicaqaPlngtieelWkmlle
VQARCIAMTTGLVEGGKNKCSRYWPATIYAETKEELVygprdgkI---HVRTmlvTKMEGYIK-TNIQVLYQGSTRN-LVHFWFTAWPDHGVPtrpDGSM
. . | | . |.| ||.| |.| . ... . .. . .. .| . ... .| .. . . . |.|.||| . .
sdveyivmlcellekGkeksaeyfPsklGekarigrl.......ctvvkkkr...adidklvkvsllriskegeekvivkilhlleWdddgvP...enyl
QTQQMIEMLldirrtrnelDRAESPLIVHCSAGIGRTGTMIALDHAMCALDMGVKVDVLSIVADIREDRMAMVQHVVQYRYLYQAVVEY
...|.| . |..||.|||.|||||.| |. .| . . . |..| ||.|. .| || |... | |.
splrllevl..........kslqkPivvhssaGvGrtgtlililialeslrlddflgirsllaklreerfkaiqtemqylyvhrcvlee
|
|||||||||
| subfamily_Urchin-PTP-4_pd | Subfamily Urchin-PTP-4 | 718-998 | 6.8e-31 | 102.0 | In-house | 28-234 (392) | alignment | ||
Range on Protein: 718-998
Range on HMM: 28-234/392.0
ELPRGETHESDLPDYARGPRLNRFRDILPNPVTRVRLEPLEVDHTLEYINANYVrdPSAPCDnkpallgfggrraKEYVAAQAPKDTGLFNFWRMIVHVQ
.|| . .. . ||...||| .||.|| .. .|.|| |. || .. | |.|.|.|. . | .||||. . .
dlpgpdiypqtvaqkeinlkknryknilpydsarvkleviddipdsdylnasyi..psfdne.............kayiasqgpnaaslddfwrmvfqen
ARCIAMTTGLVEGGknkcsrywpatiyaetkeelvygprdgkihvrtmlvtkmegyiktniqvlYQGSTRNLVHFWFTAWPDHGVPTRpdgsmqTQQMIE
. ||| | | || ..| | || |||..|| . | ...
vttiamvtklkegd..................................................kgddartvaqfhftewPdkdvpkh......tssllk
MlldIRRTRNELDRAESPLIVHCSAGIGRTGTMIALDHAMCALDMGVKVDVLSIVADIREDRMAMVQHVVQYRYLYQAVVE
. |. . . . |||.|||||.|||| .|..| .. |||. .|..||. | ||| || ..| ||.|
f...ikevkadfGqythpliihcsagvgrtgvvisidsvvahakktrmvdvfnfvtnirrkrpymvqtkeqyafiygavle
|
|||||||||
| subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 723-1003 | 2.6e-51 | 169.6 | In-house | 36-286 (319) | alignment | ||
Range on Protein: 723-1003
Range on HMM: 36-286/319.0
ETHESDLPDYARGPRLNRFRDILPNPVTRVRLEPLEVDHTLEYINANYVRdpsapcdnkpallGFggRRAKEYVAAQAPKDTGLFNFWRMIVHVQARCIA
.. . | . . . ||...||. ||| | .|. . .||||... |. .. ....|.|||... . .||||. . .. ..
vndtfdsaskeenkkknryqnilaydrtrvvlseldgvegsdyinasfid.............gy..qerekfiatqaPlentiedfWrmvWeeessivv
MTTGLVEGGKNKCSRYWPATIYAEtkeelvYgprdGKIHVRTMLVTKMEGYIKTNIQVLYQG---STRNLVHFWFTAWPDHGVPTrpdgsmQTQQMIEML
| |.||| .| |...||| . . | | |.. | ..|.||. .... . ||...|| .|.||||.||. ........|
mltklveklkvklkkywpeenfee......y....GrlivtleeeeeledyiirklklnkkssevetRevkhfqyteWpdhdvPe......katslldll
LDIRRTRNEldRAESPLIVHCSAGIGRTGTMIALDHAMCALDMGVKVDVLSIVADIREDRMAMVQHVVQYRYLYQAVVEYAERL
.||..|.. . |..||||||.||||| |.|| .. . .|| |.| .| | |||. ||...|.|..|..|
krirksrek..tqsgPivvhCsaGvGRtGtfivldamlervkeegvlDvfstvsrlRtqRnimvqrpeqYkfiyealleaveag
|
|||||||||
| subfamily_PTPRB_pd | Subfamily PTPRB | 726-1002 | 3.6e-62 | 205.1 | In-house | 42-287 (293) | alignment | ||
Range on Protein: 726-1002
Range on HMM: 42-287/293.0
ESDLPDYARGPRLNRFRDILPNPVTRVRLEPLEVDHTLEYINANYVRDPSAPcdnkpallgfggrraKEYVAAQAPKDTGLFNFWRMIVHVQARCIAMTT
. . . |. ||...||| .||.|..|. ... .||||||... ..| .|..|.| | . . .||||. ... | | |
avkaaelavnraknrytnilpydhsrvkLaalkdesgsDYinanyipgynsp...............refiatqGPlpetvddfWrmvwekkssiivmlt
GLVEGGKNKCSRYWPATiyaetKEELVYgprdGKIHVRTMLVTKMEGYIKTNIQVLYQGSTRNLVHFWFTAWPDHGVPtrpdgsMQTQQMIEMLLDIRRT
|||.|| || .||||. .|. .| |.|.| . ...| .. .... . ..|.. .. ||.||||||| .|....... .|..
qlvekgkvkCeeYWPad.....eepvly....GdikvtlvaeeeledwvirelkiekekeerkvrqyhftsWpdhgvP......ektktlldfvrtvrea
rNELDRAESPLIVHCSAGIGRTGTMIALDHAMCALDMGVKVDVLSIVADIREDRMAMVQHVVQYRYLYQAVVEYAER
| . ...|..||||||.||||| ||||. . |.. ||...|||..||.|. .|| . || ...|.|... ..
.iektaskrPivvhCsaGvGRtGtfialdrllqaieeedyvdifgivaelReeRnllvqtekqYifihqcvldllrk
|
|||||||||
| subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 726-1000 | 2.5e-50 | 166.4 | In-house | 37-283 (305) | alignment | ||
Range on Protein: 726-1000
Range on HMM: 37-283/305.0
ESDLPDYARGPRLNRFRDILPNPVTRVRLEPLEVDHTLEYINANYVRdpsapcdnkpallgfGGRRAKEYVAAQAPKDTGLFNFWRMIVHVQARCIAMTT
|. . ||...| . . |..| . | .. .||||.|| | .| |.|..||.| .. . .|||.||... . | | |
sidvgkkeankaknrlkeitlldddriiltekeslddsdyinasyvd...............gykrkkkyivaqgPlkntvadfWrliveekvstivmlt
GLVEGGKNKCSRYWPATIyaetKEELVYgprdGKIHVRTMLVTKMEGYIKTNIQVLY---QGSTRNLVHFWFTAWPDHGVPTRpdgsmqTQQMIEMLLDI
.||||||.|| .||| .. .|. . |...| .....||. .... . .|..... .| |||||||. . ..... ..
klveggkdkCrqYWpesk....tekkef....gefsvelksektasdyieRklkisiededkesrtvlqyqltdWPdhGvpqf......atsllslikrv
RRTRNEldRAESPLIVHCSAGIGRTGTMIALDHAMCALDMGVKVDVLSIVADIREDRMAMVQHVVQYRYLYQAVVEYA
...... . ||.||||||.||||. ||.| |. | ||| .. .|. || ||| || .|..|. |.
qkdqkk..dkgvpllVhCsagvgRtGvfiavdialerlkkEevvdvfevlkqlRskrmkmvqtldqYvflhdaldeli
|
|||||||||
| 0050432 | (Phosphotyrosine protein) phosphatases II | 729-1002 | 6e-68 | 224.8 | In-house | 62-301 (308) | alignment | ||
Range on Protein: 729-1002
Range on HMM: 62-301/308.0
LPDYARGPRLNRFRDILPNPVTRVRLeplevDHTLEYINANYVRDPSapcdnkpallgfgGRRAKEYVAAQAPKDTGLFNFWRMIVHVQARCIAMTTGLV
. .||..||||. .||.| |.. ||||.||. .| .. ....|.|.|... . .||||. . . |.| | | ||
vallpenkdkNrykdilpydhsRVkl.....degsdYInAsyvdgys.............sklprkfIatqgPlpntvedFwrmvweqnvrvIvmLtklv
EGGKNKCSRYWPATIYAETKEElvygprdGKIHVRTMLVTKMEGYIKTNIQVLY--QGSTRNLVHFWFTAWPDHGVPTRpdgsmqTQQMIEMLLDIRRTR
| |..|| .||| .. ...| ||..|... ......|....... . | .| . ||..|.|||||||. .......| .|...
engrekcaqYwplelgggsley.......gkftvtllseevlddytvrtleltnlgdgesrtvthfhytnWpdhgvPps......peilldflelvrksl
neldrAESPLIVHCSAGIGRTGTMIALDHAMCALDMGVKVDVLSIVADIREDRMAMVQHVVQYRYLYQAVVEYAER
..| .||||||.|||||.||||.... |... .|||...|. .|| |. ||| . ||..||.|..||...
.....pggpivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkklReqRpgmvqtpeqylflyralleylkl
|
|||||||||
| subfamily_PTPN5_RR_pd | Subfamily PTPN5_RR | 730-1004 | 1.5e-63 | 209.5 | In-house | 23-272 (274) | alignment | ||
Range on Protein: 730-1004
Range on HMM: 23-272/274.0
PDYARGPRLNRFRDILPNPVTRVRLEPLEVDHT-LEYINANYVRDPSapcdnkpallgfggRRAKEYVAAQAPKDTGLFNFWRMIVHVQARCIAMTTGLV
.| .. . ||...||||. .|| ||. .... ..||||||.. .. .. | |||.| | . ...||||| . ... | |.| |
ldvfgsqtknryktilPnensrvllesessededssyinanyikGyd..............eeskayvatqGPlpntvadfWrmiyqeevqvivmltklk
EGGKNKCSRYWPatiyaeTKEELVYGPRDGKIHVRTMLVTKMEGYIKTNIQVLYQGSTRNLVHFWFTAWPDHGVPTRPdgsmqtQQMIEMLLDIRRTRNE
| ..||..|.| ..|.. | |...... ... ..| ... ..|. ..|...|.|.|.|||| .| .. .......|.....|.|
eaneqkCavyfP......daedyeiserygdveikvekiverndysvrklvlkylerersvkhywytdWPdhksPdda......ntlldlvleveesree
LDRAESPLIVHCSAGIGRTGTMIALDHAMCALDMGVKVDVLSIVADIREDRMAMVQHVVQYRYLYQAVVEYAERLA
. .| .||||||||||| || . |. |. .||||.||...| || ||| ||.....|...|..||.
enaklapvvvhCsaGiGrtGcfiaisiavrqlreeivvdvlkivcnlrldrGGmvqtseqyelihralclylkrll
|
|||||||||
| 0049772 | (Phosphotyrosine protein) phosphatases II | 731-1003 | 2.9e-30 | 101.5 | In-house | 42-283 (314) | alignment | ||
Range on Protein: 731-1003
Range on HMM: 42-283/314.0
DYARGPRLNRFRDILPNPvTRVRLEPLEVDHtLEYINANYVRDPsapcdnkpallgfggrraKEYVAAQAPKDTGLFNF----------WRMIV--HVQA
|. ... ||. |||| . .||.| |.|. ||||.||. . . ..|.|.|.. ....| |||.. .
dlflnrdknryldilpad.nrvilpglpvsg.sdyinasyvdgf..................lkfIatqgpleitvvdfreepvlyyngwrmvlrgdlnv
RCIAM---------------------TTGLVEGGknkcsR-YWPATIYAETkeelvygprdgkihvrtmlvtkM-------EgyiktniqvlyqgsTRNL
| | | ..| ..| ...|.. .|.
rdivmsrdevladelsrLdaAlgKtpllildgng.....neptaadlellk......................eelydpelf..............erlg
VHFWFTAWPDHGVPTRPDgsmqtqqmiemlldIRRTRNELD--RAESPLIVHCSAGIGRTGTMIALDHAMCALdmgvKVDVLSIVADIREDRM-----AM
.... . .||...|. | ... . .. ....|..|||.||.|||||..... | .| .|.. ...|.|. |. .
ikylripvpDgsaplled..............fdeflefieeadkggpvlvHCkaGkgRtgtfvvaaylmkll....gvsleealedvrlkRpinpnpgf
VQHVVQYRYLYQAVVEYAERL
.. || . ..|. || ..|
ieqleqyefilealleylkfl
|
|||||||||
| 0045098 | (Phosphotyrosine protein) phosphatases II | 732-1002 | 1.5e-54 | 180.6 | In-house | 30-274 (278) | alignment | ||
Range on Protein: 732-1002
Range on HMM: 30-274/278.0
YARGPRLNRFRDILPNPVTRVRleplevdhtlEYINANYVrdpsapcdnkpallgfGGRrAKEYVAAQAPKDTGLFNFWRMIVHVQARCIAMTTGLVEGG
| . .||..||||.. .||. .||||.|. | |...|.|.|... . .||||. . . ..| | |.|||.|
ylgnldknRykdilpydhsrVk..........dYINAsyi................dgy.pkkfIatqgPlpstvadfwrmlwelgitvivmltelvelg
KNKCSRYWPAtiyaetKEELVYgprdGKIHVRTMLVTKMEGYIKTNIQVL------YQGSTRNLVHFWFTAWPDHGVPTRP--DGSMQTQQMIEMLL---
..|| .||| .. |.| |...|... .. .. |... . | . . .|.. |.... |||||||. | . . ..|. |
rekcaqywpe......ggslty....gdftvtllseevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkll
-DIRRTRNELDRAESPLIVHCSAGIGRTGTMIALDHAMCALdmGVKVDVLSIVADIREDRMA-MVQHVVQYRYLYQAVVEYAER
. .... |. . | .||||||.|||||..|.. .. | . .||.|..|. .|. |. .||. |||.||....|. .|
aslllsslllldsggpvlVHCsaGvgRtGtlvaaylmlell..eggvdlleavkelrsqRpglavqnleqyrflyefllelllr
|
|||||||||
| subfamily_Cele-PTP-15_pd | Subfamily Cele-PTP-15 | 732-1000 | 6.8e-23 | 76.0 | In-house | 32-270 (285) | alignment | ||
Range on Protein: 732-1000
Range on HMM: 32-270/285.0
YARGPRLNRFRDILPNPVTRVRLEplevDHTLEYINANYVRDPsapcdnkpallgfgGRRAKEYVAAQAPKDTGLFNFWRMIVHVQARCIAMTTGLVEGG
| | |||. |. ||| |. .| .|| |...| | |. |...| | | .||.|| . . . | |.|||
yeanpdlnryadvrcieetrvvlk....nhdrdyihaswmrmp..............gkdqstyittqgplpetlsdfwhmiyqekiayvlmlctlfegg
KNKCSRYWPATIYAETKeelvYGPRdgKIHVRTMLVTKMEGYIKTNIQVLYQ----GSTRNLVHFWFTAWPDHGVPTrpdgsmQTQQMIEMLLDIRRtrn
.||. |.| . | .| .| . . | | .. |. . | |||. | ... |||. ...
vekcalyypeklgevvk....fgky..eitlteckeeaiagtilnaltvintedasseplymnhvqvpwwpdqlape......darpmielykwvkk...
eLDRAESPLIVHCSAGIGRTGTMIALDHAMCALDMGVKVDVLSIVADIREDRMAMVQHVVQYRYLYQAVVEYA
.. | |. ||||||.||| |.. .|.| . ....| || ..| |. || .|. .|| ..||
.vnpkekpicvhcsagvgrtatfvgidyatirimenpniemldivremramrfqavqshmqflflyvvlmeyf
|
|||||||||
| 0046845 | (Phosphotyrosine protein) phosphatases II | 733-1002 | 1.6e-65 | 216.6 | In-house | 26-276 (284) | alignment | ||
Range on Protein: 733-1002
Range on HMM: 26-276/284.0
ARGPRLNRFRDILPNPVTRVRLEPLEVD-HTLEYINANYVRDPSAPCDnkpallgfggRRAKEYVAAQAPKDTGLFNFWRMIVHVQARCIAMTTGLVEGG
.||..||||. .||.| .|. | .. .||||.||. .. . .. |...|.|.|... . .||||. . ..|.| | |.||| |
penlsknRykdilpydhsRVklksldgdledsdYinAsyvdgydldlt..........yikkkfIatqgPlpntvedFwrmvweqnvrvIVmltelveng
KNKCSRYWPATiyaetKE---ElvygprdGKIHVRTMLVTKMEGYIKTNIQVLY---QGSTRNLVHFWFTAWPDHGVPTRpdgsmqTQQMIEMLLDIRRT
..||..||| . .| |...|... ......|....... . | .| . ||..|.|||||||. .....|.| ..|.
rekcaqYwple.....gevlty.......gdftvtllseevkddytvrtleltnlgytgesrtvthfhytswpdhgvpps......pedlleflrlvrel
RNElDRAESPLIVHCSAGIGRTGTMIALDHAMCALDMGV---KVDVLSIVADIREDRMAMVQHVVQYRYLYQAVVEYAER
... ..| .||||||.|||||.||||.... |. . .||||..|. .|| |. ||| . |||..|.|..||. .
len.lpgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvqtleqyrfvyealleylkl
|
|||||||||
| 0039614 | (Phosphotyrosine protein) phosphatases II | 733-1001 | 1.3e-59 | 197.5 | In-house | 54-290 (297) | alignment | ||
Range on Protein: 733-1001
Range on HMM: 54-290/297.0
ARGPRLNRFRDILPNPVTRVRLEPLEV-DHTLEYINANYVRDPSApcdnkpallgfggrRAKEYVAAQAPKDTGLFNFWRMIVHVQARCIAMTTGLVEGG
.||..||||.. .||.| |.. |. . ||||.|| .. . ....|.|.| . . .||||. . . ..| | | ||| |
penkdknrykdilpydhsrvklkpedgvdldsdYinAsyvdgydl..............ltrkfIatqgPlpetvedFwrmvweqgvtvivmLtklvelg
KnKCSRYWPATIYaetkeelvygpRDGKIHVRTMLVTKMEGYIKTNIQVLYQGSTRNLVHFWFTAWPDHGVPTRPDGSMQTQQMIEMLLDIRrtrneldR
. || .||| . . |...|... |.. .||. ... | . | .| . ||..| ||||||| .. .. .... | .
r.kcaqywpeegg...........tygdftvtllkvehldgytvrtlevtnngesrtvthfqytgwpdhgvppslellleflelvrealael.......p
AESPLIVHCSAGIGRTGTMIALDHAMCALDMGVKVDVLSIVADIREDRMAMVQHVVQYRYLYQAVVEYAE
. | .||||||.|||||.||.. ... |. . .||||..|. .|| |. .|| |||.||.|..|.
kggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavqtpsqyrflydallellk
|
|||||||||
| subfamily_Sponge-PTP5_pd | Subfamily Sponge-PTP5 | 734-1000 | 2.3e-35 | 116.9 | In-house | 32-266 (283) | alignment | ||
Range on Protein: 734-1000
Range on HMM: 32-266/283.0
RGPRLNRFRDILPNPVTRVRLEPLEVdhtlEYINANYVRDpsapcdnkpallGFGGRRAKEYVAAQAPKDTGLFNFWRMIVHVQARCIAMTTGLVEGGKN
. .| ||...|.| . ||.|... .|||| .. .. |.|..||.| | .||.|. . .. .| | | | |. .
enkrknrnqeivpadqwrvelksesr....dyinavfipv............sksykqdkkyiiaqsPldrtvvdfWkmvfdekitaivmltklqedlri
KCSRYWPAtiyaETKEElvYGPRdgKIHVRTMlvTKMEGYIKTNIQVLYQGSTRN---LVHFWFTAWpdhgvptrpdGSMQTQQMIEMLLDIRRT-RNEL
|||.||| . |. ||. . .| | . .|. .. . ...|... | |. . | ... | .|. |. . . .
kCsqyWPk....rGsed..yGef..tvtlrke..ttsnsfiikelllrvnssakstlllahyqvidW..........leygeqaiinslvkfnkvislqt
DRAESPLIVHCSAGIGRTGTMIALDHAMCALDMGVKVDVLSIVADIREDRMAMVQHVVQYRYLYQAVVEYA
. ..|..||||.|||||...||. .. . ||| ..| .||.|| .|| ||. ....|.| |
eskkgPivvhCstgiGrtavfiaasasvkdaltesvvdvfavvkimreqrmmavqtldqyklvhelvleqa
|
|||||||||
| 0051299 | (Phosphotyrosine protein) phosphatases II | 735-1000 | 2.8e-66 | 219.3 | In-house | 49-286 (288) | alignment | ||
Range on Protein: 735-1000
Range on HMM: 49-286/288.0
GPRLNRFRDILPNPVTRVRLEPLEVDHTLEYINANYVRDPSAPcdnkpallgfggrraKEYVAAQAPKDTGLFNFWRMIVHVQARCIAMTTGLVEGGKNK
||..||||. .||.| .|. ... ||||.|.. . . ....|.|.|... . .||||. . . |.| | |.||| |..|
nleknRysdilpydhsRVkLsvldgvegsdYinAsyidgynlk...............rkfIatqgPlpntvedFWrmvweqnvrvIvmltklvelgrek
CSRYWPAtiyaetKEELVYGPrdgkIHVRTMLVTKMEGYIKTNIQVL------YQGSTRNLVHFWFTAWPDHGVPTrpdgsmQTQQMIEMLLDIRRTRNe
| .||| .. |.||. |.|... ......|......| ..| .|. ||..|.|||||||. .......| ..|. ..
caqYwpl......ggsltygd....itvtllseevlddytvrtlevtnldlldgdgesrtvthfhytnwpdhgvpd......spellldflrlvrkala.
ldRAESPLIVHCSAGIGRTGTMIALDHAMCALDMGVKVDVLSIVADIREDRMAMVQHVVQYRYLYQAVVEYA
..| .||||||.|||||.||||.... |. . .||||..|. .|| |. ||| . |||..|.|..||.
..sgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlreqRpgmvqtpeqyrfvyealleyl
|
|||||||||
| 0040439 | (Phosphotyrosine protein) phosphatases II | 735-999 | 7e-55 | 181.7 | In-house | 11-245 (249) | alignment | ||
Range on Protein: 735-999
Range on HMM: 11-245/249.0
GPRLNRFRDILPNPVTRVRLEPLEVDHTLEYINANYVrdpsapcdnkpallgFGGRRAKEYVAAQAPKDTGLFNFWRMIVHVQARCIAMTTGLVEGGKNK
. .||..||||.. .||.|..|. ||||.|. | .. ....|.|.| . . .||||. . . ..| | | ||| |..|
nkdknrypdilpydhsrvklsilpglflsdyinAsyi...............dgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrek
CSRYWPAtiyaetKEELVYgprdGKIHVRTMLVTKMEGYIKTNIQVL--YQGSTRNLVHFWFTAWPDHGVPTRPDGSMQTQQMIEMLLDIRrtrneldRA
| .||| ...|.| |...|... |.....|. ..... | |..| |...| ||||||| .. .. .... |. .
caqywpl......ggsley....gdftvtllsvevkddytvrtleltnlydgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleel.......pk
ESPLIVHCSAGIGRTGTMIALDHAMCALDMGVKVDVLSIVADIREDRMAMVQHVVQYRYLYQAVVEY
..|..||||||.|||||.||.. ... |. .||....|...|. |. .|| |||.||.|. |.
ggpvlVHCsaGvgRtGtfiaaylmleqlekelgvdleeavkllrsqRpgavqnpeqyrflyeallel
|
|||||||||
| 0047943 | (Phosphotyrosine protein) phosphatases II | 736-1000 | 1.9e-60 | 200.0 | In-house | 39-272 (273) | alignment | ||
Range on Protein: 736-1000
Range on HMM: 39-272/273.0
PRLNRFRDILPNPVTRVRLepleVDHTLEYINANYVRDPsapcdnkpallgfggRRAKEYVAAQAPKDTGLFNFWRMIVHVQARCIAMTTGLVEGGKNKC
.||..||||. .||.| | . ||||.||. . .. ....|.|.|.. . .||||. . ..|.| | | ||| |..||
kdknrykdilpydhsrvkl....gdggsdyinAsyvdgy...............nlkrkfiatqgPlpntvedfwrmvweqnvrviVmLtelvelgrekc
SRYWPATIYAetkEELVYGPrdgkIHVRTMLVTKMEGYIKTNIQVLY--QGSTRNLVHFWFTAWPDHGVPTRPDGSMQTQQMIEMLLDIRRTRneldrae
.||| . .|.||. ..|... ... ..|....... . | .| ||..| |||||||. .. .. .... | .
aqYwplegge...lsltygk....ftvtllseetkddytvrtleltnlgtgesrtvthfhytgwpdhgvppslesllefielvrkalealpsn.......
SPLIVHCSAGIGRTGTMIALDHAMCALDMGVKVDVLSIVADIREDRMAMVQHVVQYRYLYQAVVEYA
.| .||||||.|||||.||||.... | .. .||||..|. .|. |. ||| . |||.||.|..||.
gpvvVHCsaGvgRtgtfialdllldqlekeggvdvleavkllrsqRpgmvqtpeqyrflyealleyl
|
|||||||||
| 0045450 | (Phosphotyrosine protein) phosphatases II | 736-999 | 3.7e-59 | 196.3 | In-house | 56-303 (307) | alignment | ||
Range on Protein: 736-999
Range on HMM: 56-303/307.0
PRLNRFRDILPNPVTRVRLEPLEVD-HTLEYINANYVRDPSAPcdnkpalLGFGGRRAKEYVAAQAPKDTGLFNFWRMIVHVQARCIAMTTGLVEGGKNK
.||..||||.. |||.| .|. . .. ||||.|||.|. |. | .. ....|.|.|.. . .||||. . . ..| | |.||| |..|
kdknrykdilpydhtRVklssldgsledsdYiNAsyvrvplll.......lldgydlkrkfIatqgPlpetvedFwrmlweqgvtvivmltelvelgrek
CSRYWPATiyaetKEELVYGPrdgkIHVRTMLVTKMEGYIKTNIQVL---YQGSTRNLVHFWFTAWPDHGVPTrpdgsmQTQQMIEMLLDIRRTRNELdR
| .||| . .|||.||. ..|... .....||. ... | . | .| . ||..|.|||||||. ........ .|. ..|| .
caqywPde.....geeltygn....ftvtllseehldgytvrtlevtdldgtgesrtvthfhytgwpdhgvpp......sfeelldfieevrkaleel.p
AESPLIVHCSAGIGRTGTMIALDHAMCALDMGVK---VDVLSIVADIREDRMAMVQHVVQYRYLYQAVVEY
..| .||||||.|||||.||.. ... |. . . ||.|..|. .|| |. .|| |||.||.|. |.
kggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrflyeallel
|
|||||||||
| 0042113 | (Phosphotyrosine protein) phosphatases II | 736-1000 | 5.9e-57 | 188.2 | In-house | 10-243 (245) | alignment | ||
Range on Protein: 736-1000
Range on HMM: 10-243/245.0
PRLNRFRDILPNPVTRVRLEPLEVDHTLEYINANYVRdpsapcdnkpallgfGGRRAKEYVAAQAPKDTGLFNFWRMIVHVQARCIAMTTGLVEGGKNKC
. .||..||||.. |||.| | . | . ||||.|| | |. . . |.|.| . . .||||. . . ..| | | ..| |..||
kdknrysdilpydhtrvklspdggdldsdyinasyvd...............gyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkc
SRYWPAtiyaetKEELVYgprdGKIHVRTMLVTKMEGYIKTNIQVL--YQGSTRNLVHFWFTAWPDHGVPTRPDGSMQTQQMIEMLLDIrrtrneldRAE
.||| .|.|.| |...|... ......|. ....| . . .|. .|.... |||||||. .. . .... | ..
aqywpl......geslty....gdftvtllseehlddytvrtlevtnlgddesrevihyhylpwpdhgvpdllellldflefvrkalae........dsn
SPLIVHCSAGIGRTGTMIALDHAMCALDMGVKVDVLSIVADIREDRMAMVQHVVQYRYLYQAVVEYA
|..||||||.|||||.||.. ... |. .|.. ..|...|. |. .|| |||.||.|. |.
gpvlVHCsaGvgRtGtfiaaylmleqlekelgvsleeavkelrsqRpgavqtpsqyrflyeallell
|
|||||||||
| subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 736-1000 | 9.2e-48 | 158.0 | In-house | 57-290 (298) | alignment | ||
Range on Protein: 736-1000
Range on HMM: 57-290/298.0
PRLNRFRDILPNPVTRVRLEPLEVDHTLEYINANYVRdpsapcdnkpallGFGGRRakEYVAAQAPKDTGLFNFWRMIVHVQARCIAMTTGLVEGGKNKC
. ||. ||.. .||.|| . |. .|||| .. .. || ..|.||| . . .||||... .. .| | | |.| .| |.
kkkNRyadiialdssRvvLekedadeesdYiNAsflh.............aykgrn..afiatqaPltetvedFWrmvteedigtiVmltnleeldktky
SRYWPATiyaeTKEElvYgprdGKIHVRTMLVTKMEGYIKTNIQVL--YQGSTRNLVHFWFTAWPDHGVPTrpdgsmQTQQMIEMLLDIRRtrNELDRAE
..||| . ||. | |.|.|. . .. .|.....| . ..|..... || |||.|||. ... ....| ..|. .. . .
hkywPde....gket..y....geitvsllskeefadlivrklkvskkkeekerevrqlhftsWpdkgvpe......natsvldllrkvra..sqqqagn
SPLIVHCSAGIGRTGTMIALDHAMCALDMGVKVDVLSIVADIREDRMAMVQHVVQYRYLYQAVVEYA
.|.||.||||.||.|| ||.| . . .|||. .| .|..|...|| || ..|.|| |.
kpvivqCsaGvgRsGtfiaidsvlervkkeqvvDvfqvvkvlRkkrpgavqteeqYvfiyeavleal
|
|||||||||
| subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 736-1000 | 8.9e-43 | 141.3 | In-house | 45-277 (315) | alignment | ||
Range on Protein: 736-1000
Range on HMM: 45-277/315.0
PRLNRFRDILPNPVTRVRLEPLEVDHTLEYINANYVrdPSAPCDnkpallgfggrraKEYVAAQAPKDTGLFNFWRMIVHVQARCIAMTTGLVEGGKNKC
. ||...||| .||.|| .. . .|||| |. .| .| | |.|.|.|... . .||||... .. |.| | . || | ||
fkknryknilPldsarvkleviddsPdsdyinasyi..ksvddd.............kayiasqgPlkasvddfwrmvlqekvttivmvtkkqegdkikc
SRYWPATiyaetKEELVygpRDGKIHVRTMLVTKMEGYIKTNIQVLYQGSTRNLVHFWFTAWPDHGVPTRPDgsmqtqQMIEMlldIRRTRNELDRAESP
.||| | ..| . |.|.| .. . . .. .. . ..|.. | || |||.||. . .... |. . . .. | .
rqywPdr.....kadsv...efGsikvellsleadtdgvarklvtrkseesrtvtqfqftewPdkGvdkqts......sllkl...ikevkadngkkefs
LIVHCSAGIGRTGTMIALDHAMCALDMGVKVDVLSIVADIREDRMAMVQHVVQYRYLYQAVVEYA
|.||||||.|||| .|..|. . . . |||. .| .|..|. .|| .| ..|.|| |.
llvhcsaGvGrtGvvisidevvaqikrtrsvdvfnfvknlrakrpylvqteeeyafiydavledl
|
|||||||||
| subfamily_Cele-PTP-14_pd | Subfamily Cele-PTP-14 | 736-1002 | 8.5e-22 | 72.1 | In-house | 53-292 (310) | alignment | ||
Range on Protein: 736-1002
Range on HMM: 53-292/310.0
PRLNRFRDILPNPVTRVRLEpLEVDHTLEYINANYVRDpsapcdNkpaLLgfggrRaKEYVAAQAPKDTGLFNFWRMIVHVQARCIAMTTGLVEGGKNKC
||. |.. .||.|. .. .|| ||||. | | | . .. .| | . . .||||| .| | . .| |. ||
mhknrysdvvcldtsrvklk.idksryedyihanyvkt......n...yl.....r.stficsqgplqhtiidfwrmifqeraesilllckvgeegrpkc
SRYWPATIYAETKEEL---VYGPRDGKIHVRTMLVTKMEGYIKTNIQVLYQGSTR-NLVHfWfTAWPDHGVPtrpDGSMQTQQMiEMLLDIRrtrneldr
|||. .|| . .. .. . . || . . . | | .|.. | ||| ||| | .| .| ..|
vgywpslgvtetygcirvtnlsesseefeicnlavtfvpdnvpvdeqpanlkelrvslik.w.pnwpdrgvp...dekchtvpq.rllaqvr........
aESPLIVHCSAGIGRTGTMIALDHAMCALDMGVKVDVLSIVADIREDRMAMVQHVVQYRYLYQAVVEYAER
| .||||||..|.....||. .. || | |||. ...... .|. .| .|| .. . . .|
.hgpcvvhcsagkdrlyvvvalklkidkldrglkvdaeevktellksraiciqtelqyliidrvriifarg
|
|||||||||
| DSPc_SM00195 | 737-1000 | 3.2e-63 | 208.9 | In-house | 28-262 (263) | alignment | |||
Range on Protein: 737-1000
Range on HMM: 28-262/263.0
RLNRFRDILPNPVTRVRLEPLEVDHTLEYINANYVRDPsapcdnkpallgfggRRAKEYVAAQAPKDTGLFNFWRMIVHVQARCIAMTTGLVEGGKNKCS
. ||...|||. |||.|.. | . . .||||||.. . .. |.|.|.|.|... . ||||... . ..|.|.| .| ||.||.
sknRyknilpydhtrVklkkeekkegsdYINAnyikga...............nkkkkyIatQgPlpstvedFWrmvweekvkiivmlteeeengkekcd
RYWPATIyaetKEELVYGprdgKIHVRTMLVTKME-GYIKTNIQVLYQG--STRNLVHFWFTAWPDHGVPtrpdgsMQTQQMIEMLLDIRRTRNELdraE
|||| .. ... ..| ||.| .. |.|.. .|...... ..| ||.. ......||||||| .|....|.| .. .... .
rywpees....ggketfg....kisvklvevekkkdeiilrtleltkegkeetrkvtqyqyknWpdhgvp......dstksvlellravkksksts...s
SPLIVHCSAGIGRTGTMIALDHAMCALDMGVKVDVLSIVADIREDRMAMVQHVVQYRYLYQAVVEYA
.|..||||||.|||||....| .. |... |||. .|| .|. |. ||| ||...|.|..||.
gpivVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaileyi
|
|||||||||
| PTPc_SM00194 | 737-1000 | 3.2e-63 | 208.9 | In-house | 28-262 (263) | alignment | |||
Range on Protein: 737-1000
Range on HMM: 28-262/263.0
RLNRFRDILPNPVTRVRLEPLEVDHTLEYINANYVRDPsapcdnkpallgfggRRAKEYVAAQAPKDTGLFNFWRMIVHVQARCIAMTTGLVEGGKNKCS
. ||...|||. |||.|.. | . . .||||||.. . .. |.|.|.|.|... . ||||... . ..|.|.| .| ||.||.
sknRyknilpydhtrVklkkeekkegsdYINAnyikga...............nkkkkyIatQgPlpstvedFWrmvweekvkiivmlteeeengkekcd
RYWPATIyaetKEELVYGprdgKIHVRTMLVTKME-GYIKTNIQVLYQG--STRNLVHFWFTAWPDHGVPtrpdgsMQTQQMIEMLLDIRRTRNELdraE
|||| .. ... ..| ||.| .. |.|.. .|...... ..| ||.. ......||||||| .|....|.| .. .... .
rywpees....ggketfg....kisvklvevekkkdeiilrtleltkegkeetrkvtqyqyknWpdhgvp......dstksvlellravkksksts...s
SPLIVHCSAGIGRTGTMIALDHAMCALDMGVKVDVLSIVADIREDRMAMVQHVVQYRYLYQAVVEYA
.|..||||||.|||||....| .. |... |||. .|| .|. |. ||| ||...|.|..||.
gpivVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaileyi
|
|||||||||
| 0036941 | (Phosphotyrosine protein) phosphatases II | 737-1002 | 3.2e-61 | 202.6 | In-house | 41-279 (297) | alignment | ||
Range on Protein: 737-1002
Range on HMM: 41-279/297.0
RLNRFRDILPNPVTRVRLepleVDHTLEYINANYVRdpsapcdnkpallgfGGRRAKEYVAAQAPKDTGLFNFWRMIVHVQARCIAMTTGLVEGGKNKCS
.||..||||.. |||.| | ||||.|| | .. ....|.|.|... . .||||. . . ..| | | ||| |..||
eknRykdilpydhtRVkl....ddegsdYinAsyvd...............gydlkrkfIatqgPlpntvedFWrmvweqnvtvIvmltelvelgrekca
RYWPATiyaeTKEELVYgprdGKIHVRTMLVTK--MEGYIKTNIQVLY--QGSTRNLVHFWFTAWPDHGVPTrpdgsmQTQQMIEMLLDIRRTRNELdRA
.||| . . |.|.| |...|... |.. ..|. ....|.. | .| . ||..| |||||||. ........ .|. ...| .
qywple....egeslty....gdftvtllsvevvllddytlrtlevtdtgngesrtvthfhytgwpdhgvpe......spaslldfielvrkvlkll.ps
ESPLIVHCSAGIGRTGTMIALDHAMCALD---MGVKVDVLSIVADIREDRMAMVQHVVQYRYLYQAVVEYAER
..| .||||||.||.||.||.| ... |. . .||.|..| .|| |. .|| . |||.||.|. |. .
ggpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyeallellkk
|
|||||||||
| subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 737-1002 | 8.4e-56 | 184.1 | In-house | 43-278 (281) | alignment | ||
Range on Protein: 737-1002
Range on HMM: 43-278/281.0
RLNRFRDILPNPVTRVRLEPLEVDHTLEYINANYVRdpsapcdnkpallgfGGRRAKEYVAAQAPKDTGLFNFWRMIVHVQARCIAMTTGLVEGGKNKCS
||...| |||...| | ... .|||||.| | . |||.|.|.| . | .||.|.. ... |.| | .|.|| ||
lknrYsnivaYDatrvkvtpneenkntDYinanfvp...............gykgekeyiatqgPvPaslvafWqmvweqkvsaivmvtreieagklkCh
RYWPATIYaetkeELVYgprdGKIHVRTMLVTKMEGYIKTNIQV-LYQGSTRNLVHFWFTAWPDHGVPTrpdgsmQTQQMIEMLLDIRRTRNEldRAESP
|||| || | |...|... .. . ||. .... .| ||..... .|||||||||. .|....| ........ . . |
rYWPddns.....elky....gdvtvkstaeeekatyierkfkleresgetreveqlaytaWPdhGvPa......ttkellefrkevlkltek..ktkap
LIVHCSAGIGRTGTMIALDHAMCAL-DMGVKVDVLSIVADIREDRMAMVQHVVQYRYLYQAVVEYAER
|..|||||.||||| |||| .. |. .. ..|| .||..|..|. ||| ||||...|.||... ..
lvihCsaGvGrtGtyialDrlvkaveaeleeldvkavvaelrkernlmvqtvvqyefvykavldaldk
|
|||||||||
| subfamily_PTPN12_pd | Subfamily PTPN12 | 737-1005 | 1.2e-55 | 183.4 | In-house | 42-282 (290) | alignment | ||
Range on Protein: 737-1005
Range on HMM: 42-282/290.0
RLNRFRDILPNPVTRVRLEPLEVDHTLEYINANYVRDPSAPcdnkpallgfggrraKEYVAAQAPKDTGLFNFWRMIVHVQARCIAMTTGLVEGGKNKCS
. ||..|||| .|| |. | .. .|||||... .. . .||.|||.| . | .||||| ... . . | .|| ||.||
kknrykDilPydksrvelskieeeegsdYinanfikgvegk...............leyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkkCe
RYWPAtiyaETKEELVYGprdgKIHVRTMLVTKME-GYIKTNIQVLYQGSTRNLVHFWFTAWPDHGVPTRPDgsmqtqQMIEMLLDIRRTRNeldRAESP
|||| |..||| .| ...| .. ... ... ..| |. .|.. | .|||||||||.... ...|.. ..|.... . ..|
rYWpe....egeeelefg....efevtleeekavdddflirtLkveaqkesrkvyqfhYtaWPDhgvPssak......sllelielvrelqe...sedaP
LIVHCSAGIGRTGTMIALDHAMCALDMGVK---VDVLSIVADIREDRMAMVQHVVQYRYLYQAVVEYAERLAA
|.||||||.|||||.||.|.. .| . .|| ..|...|..| |.|| ||...|.||.|. .. .
lvvhCsaGvGrtGtiiaidyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavaelvqkele
|
|||||||||
| 0037934 | (Phosphotyrosine protein) phosphatases II | 737-999 | 1e-51 | 171.2 | In-house | 12-241 (243) | alignment | ||
Range on Protein: 737-999
Range on HMM: 12-241/243.0
RLNRFRDILPNPVTRVRLeplevDHtLEYINANYVRDPsaPcdnkpallgfggrrakEYVAAQAPKDTGLFN----FWRMIVHVQARCIAMTTGLVEGGK
||..||||.. .||.| . |||||... . | . | |.| . ... ||||. . . ..| | | ||| |.
sknrysdilpydhsrvkl.....eg.sdyinanliyvt..p................rliatqgPlpetveddlasfwrmlwelgitvivmltelvElgr
NKCSRYWPatiyaetkEELVYGPrdgkIHVRTMLVTKMEGYIKTNIQVLY---QGSTRNLVHFWFTAWPDHGVPTRpdgsmqTQQMIEMLLDIRRTRNE-
.|| .||| .| .||. ..|... .. ...|. ..... . .. ||. .|.....|||||||. .......| ..| .|
ekcaqywp........gevtygd....ftvtllseehlddytvrtlllenldlddltrlvihyhylpwpdhgvPds......pedlldfldevrefieel
----LDRAESPLIVHCSAGIGRTGTMIALDHAMCALdmgvKVDVLSIVADIREDRMA-MVQHVVQYRYLYQAVVEY
. ..|..||||||.|||||.||.. . | .||....|...|| |. .|| |||.||.|. |.
lsllaldsggpvlVHCsaGvgRtGtliaaylmllll....gvdleeavkllreqRpgkavqtpsqyrflyeallel
|
|||||||||
| subfamily_PTPN9_pd | Subfamily PTPN9 | 737-1003 | 2.3e-50 | 166.3 | In-house | 44-293 (297) | alignment | ||
Range on Protein: 737-1003
Range on HMM: 44-293/297.0
RLNRFRDILPNPVTRVRLEPLEVDHTLEYINANYVRdpsapcdnkpallgfGGRRAKEYVAAQAPKDTGLFNFWRMIVHVQARCIAMTTGLVEGGKNKCS
. ||. |.| ||| |. .. |.. .|||||.| | .. | ..|.| | . .||||. ... | ||| .|| |. ||.
eknrytdvlcydetrvvlakvdedeasdyinanfvd...............GykqkkafiatqGplkktvsdfWrmvWeqevlvivmttrvvergrlkcg
RYWPATiyAETKEElvYgprdGKIHVRTMLVTKMEGYIKTNIQVL--YQGSTRNLVHFWFTAWPDHGVPTRPDGSMQTQQMI----EMLLDIRRTRNELD
.||| . |. .| . |...|... | ..| | .. ... .. .|...|| |..|||.||| .. ... .. . ... .
qyWple..eessae..f....gdlsvsnveveeeedykvrvleiknvkteesrkvthfqflsWPdyGvPssaaslldvlekvrekqalavkelgdewkgh
RAESPLIVHCSAGIGRTGTMIALDHAMCALDMGVKVDVLSIVADIREDRMAMVQHVVQYRYLYQAVVEYAERL
. |..||||||||||||.|.|| .. |.. .||| | .|. | ..| || . |.||.||| .|
psgPPivvhcsaGiGrtGtfitldiclsrleevgtvdvvetvkllrtqrafsiqtpeqyefcylavleyalel
|
|||||||||
| subfamily_PTPN13_pd | Subfamily PTPN13 | 737-1002 | 3.1e-50 | 165.9 | In-house | 39-271 (273) | alignment | ||
Range on Protein: 737-1002
Range on HMM: 39-271/273.0
RLNRFRDILPNPVTRVRLEPLEVdhtleYINANYVRDPSapcdnkpallgfgGRRAKEYVAAQAPKDTGLFNFWRMIVHVQARCIAMTTGLVEGGKNKCS
. ||.|..|| |||.|. ||||.... | | ||.|.| | . .||.|. .|. ||| | .|.|| ||
dknryrnvlPydetrvklgdegg.....yinaslikvpv.............gkdeyeyiacqGPlPetvkdfwqmvweqkaeviamvtlekekgkvkch
RYWPATIYAETKeelVYgprdGKIHVRTMLVTKMEGYIKTNIQVLY--QGSTRNLVHFWFTAWPDHGVPTRPdgsmqtQQMIEMLLDIRRTRNeldrAES
|||| . ..| |. ....|. . |.|..|. ...| | .|...|. |..|||||||. . ....... .|| .. ..
rywPesknkklk...vs....nrlevellkvqkldgfvvralavkdsesgesrevahlnfvkwPdhgvPssa......aellqfvaevrrlqt....dag
PLIVHCSAGIGRTGTMIALDHAMCALDMGVKVDVLSIVADIREDRMAMVQHVVQYRYLYQAVVEYAER
|..|||||||||.||.|..| .. .. ..|| || ..|| | ..|| || . |.|..| ..
PivvhcsaGiGrsGtlitidvvlglierdkefdvkeivrklreqrqgvvqtkdqyifvykailevlks
|
|||||||||
| subfamily_PTPN23_pd | Subfamily PTPN23 | 737-1005 | 6.5e-47 | 154.7 | In-house | 45-285 (288) | alignment | ||
Range on Protein: 737-1005
Range on HMM: 45-285/288.0
RLNRFRDILPNPVTRVRLEplevDHTLEYINANYVRDPSAPCdnkPAllgfggrrakeYVAAQAPKDTGLFNFWRMIVHVQARCIAMTTGLVEGGKNKCS
||.||||| .|| |. ... .|||| .|.| |. | | ..|.|||... | ||.|... ... | | . | ||.|..
eknrsrdilPyDhnRvklr....gskDDYinAsfvkdlspgc...Pd...........fiatqaPlqstlnDFWlmvyeqkssviVmllskeelgkpkvd
RYWPAtiyaETKEELVYGPrdgkIHVRTMLVTKMEGYIKTNIQ--VLYQGSTRNLVHFWFTAWPDHGVPTRPDGSMQTQQMIEMLLDIRRTRNELdraes
||||. .. | ..|. ..| |...| ... ... .| . .....| .|.||..||| |. .| . .| .. .. . .
rYwPe....dkgetvkfgd....lsvtlksvretethvervlkletldadavksvshlqltsWpelGvPasPetllqfldevesayeavqrkskt.....
PLIVHCSAGIGRTGTMIALDHAMCALDMGVK-VDVLSIVADIREDRMAMVQHVVQYRYLYQAVVEYAERLAA
||.||||||.||||.. . |. .|. | .|.. .| .||.| |||.. |.. .|.||.|.|.|
PlvvhCsaGvgRtgvfalvyaavrelekgnglldiiqvvsrlreqRrfmvqekeqlkfsyeavleaarrvld
|
|||||||||
| subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 737-1003 | 9.5e-39 | 128.0 | In-house | 48-286 (290) | alignment | ||
Range on Protein: 737-1003
Range on HMM: 48-286/290.0
RLNRFRDILPNPVTRVRLEPLE--VDHTLEYINANYVRDPSapcdnkpallgfggrRAKEYVAAQAPKDTGLFNFWRMIVHVQARCIAMTTGLVEGGKNK
.||||..|... |. | |. | | ||||| |. . . .|.|.|.|.| | .||..|.. . .| | | .| ||.|
llnRfanivvyddnritLrpisghkDCtneyinAcyikgyk...............ekkqyiatqgpvsntlvdFWkliwqekvtiivmltniieegkvk
CSRYWPATiyaETKEelvYGPrdgkIHVRTMLVTKMEGYIKTNIQVLYQGS---TRNLVHFWFTAWPDHGVPTRPDGSMqtqqmieMLLDiRRTRNELDR
| |||.. .||. ||. .... . .....||.....| . | ....... .|.|...| | | ... ... ...... |
CqqYWpds...dtka...yge....fsikllneetlneyierklevknknsagakqsvtqyqitnwdstgkvtnpqtil.......lvie.emyktqrkr
AESPLIVHCSAGIGRTGTMIALDHAMCALDMGVKVDVLSIVADIREDRMAMVQHVVQYRYLYQAVVEYAERL
. ...||||...||... .|.. .. . .||.... | .. .|| |.||....| |..| ...
gntsivvHCSdtvgrsavfcaaattinkcktegvidvfqvlksqRiqkpgsvqtvqqyqgifqivltyldsf
|
|||||||||
| subfamily_PTPN1_pd | Subfamily PTPN1 | 737-1003 | 4.8e-38 | 125.5 | In-house | 34-274 (290) | alignment | ||
Range on Protein: 737-1003
Range on HMM: 34-274/290.0
RLNRFRDILPNPVTRVRLEPLEVdhtlEYINANYVRDPSApcdnkpallgfggrrAKEYVAAQAPKDTGLFNFWRMIVHVQARCIAMTTGLVEGGKNKCS
|||.||. | .|..|| .. .||||. | . | ..|. .| | ||.|. . ..... | .|| ...||
nlnryrdvspydhsrikleradn....dyinaslveleea...............krsyiltqGPlpntvdhfWqmvWeqkskavvmlnkvvekeqikca
RYWPATIYaetKEELVYgpRDGKIHVRTMLVTKMEGYIKTNIQV--LYQGSTRNLVHFWFTAWPDHGVPTRPDgsmqtqQMIEMLLDIRRTrNELDRAES
.||| ..||.. | |..|. . . . |. ... | ||...|| .|.||| ||| | .....| ..|.. | .
qywPqgee...ekelll..edtklkvkliseerksyytvrllelenlktqetreilhfhyttwpdfgvpespa......aflkflfkvres.GslssdvG
PLIVHCSAGIGRTGTMIALDHAMCALDMGVK---VDVLSIVADIREDRMAMVQHVVQYRYLYQAVVEYAERL
| ..||||||||.||.. .| . .. . ||. . ..|. |. ..| | |. |.|..| | .
pavihcsaGiGrsGtfclvdtclvliekkddlssvdikkvllelrkyrlGliqtadqlrfsylaileGakvi
|
|||||||||
| subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 737-997 | 1.2e-35 | 117.8 | In-house | 35-292 (297) | alignment | ||
Range on Protein: 737-997
Range on HMM: 35-292/297.0
RLNRFRDILPNPVTRVRLepLEVDHTLEYINANYVRDPSAPCDNKpallgfggrrakeYVAAQAPKDTGLFNFWRMIVHVQARCIAMTTGLVEGGKNKCS
| ||.|||| |||.| | | .||||.|| | . | | |. || | .. . .||..... . | |.| . | |.|..||
rknryrdilatddtrvkl..lrviterdyinadyvvfpdeeadlk.............yilaqGplsatvddfwtlvaeqdvrvivmvaklqedGrdkca
RYWPATIYAETKEELVYgprdgKIHVRTMlVTKMEGYIKTNIQVLYQGSTRNLVHFWFTAWPDHGVPTRPDGSMQT--------------QQMIEM----
||| . | | .. .. . . | |..|..|. .| . | | .|||||||. . . ..||
pywpsvvqerlkagdvv.....veflsst.sdefdrviltelqliyrsesrvvrhvqflswpdhGvpsdledlvrfqaqvcscciavpmmlalvemftam
-LLDIRRTRNELDRAeSPLIVHCSAGIGRTGTMIALDHAMCALDMGVKVDVLSIVADIREDRMAMVQHVVQYRYLYQAVV
.| . | | | .|.||||||.||.| .. | . | . || .|. .|| | .|| . |. .||.||.
vflqleslraemprn.ayllvhcsaGvGrsGvvvlsdvilaklrkkripdvaailsilreqrarlvqtleqfellydavl
|
|||||||||
| subfamily_PTPRN_pd | Subfamily PTPRN | 737-1000 | 3.9e-31 | 102.9 | In-house | 58-292 (297) | alignment | ||
Range on Protein: 737-1000
Range on HMM: 58-292/297.0
RLNRFRDILPNPVTRVRLEPLEVDHTLEYINANYVRDpsapcdNKPallgfggrRAKEYVAAQAPKDTGLFNFWRMIVHVQARCIAMTTGLVEGGKNKCS
. || ...|| .||.|. ... .|||| . | . | || |.|.|.| . . .||.|. . . | . | | | | ..|.
kknrskavlpydhsrvklkeeasaeksdyinasaild......hdp........rapayiatqgplastvadfwqmvweqGvvvivnltrleeegvkqck
RYWPAT---IYAETKEELVygprDGKIHVRTMLVTKMegYIKtNIQvlyQGSTRNLVHFWFTAWPDHGVPTRPdgsmqtqqmiEMLLDIRRTRNELDRAE
|||| . .| . .|| .| || . |.| |.| . || . | | .||..|||. . ||. || | |
rywpdeGsevyhiyevhlv....sehiwcddylvrsf..ylk.nlq...tsetrtvtqfhflswpeegvPasa..........ksllefrrkvnksyrGr
-SPLIVHCSAGIGRTGTMIALDHAMCALDMGVK-VDVLSIVADIREDRMAMVQHVVQYRYLYQAVVEYA
.|..||||.| ||||. |..| . | ||| .|. . . .|..| .|. |... ..||.|
scpivvhcsdGaGrtGvyilidlvlnrllkGvkeidiaatlehlrdqrpglvktkdqfefaltavaeev
|
|||||||||
| subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 737-1000 | 3.1e-30 | 99.8 | In-house | 58-283 (290) | alignment | ||
Range on Protein: 737-1000
Range on HMM: 58-283/290.0
RLNRFRDILPNPVTRVRLEpleVDHTLEYINANYVRdpsapcdnkpallgfgGRRAkEYVAAQAPKDTGLFNFWRMIVHVQARCIAMTTGLVEGGKNKCS
. ||..|. | .||| |. . .|. ||||. | .| .. .| . ...|||... .. | | |.| || ||.
kknrykdvvcndktrvilk...dGydGdyvhanyvk................Glka.mfiltqGalkdtvidiwrmvlqekvaaivmlceliedGkakce
RYWPATiyaeTKEELVYGprdgKIHVRTMLVTKMEGY-IKTNIQVL--YQGSTRNLVHFWFTAWPDHGVPTrpdgsmQTQQMIEMLLDIRrtrneldRAE
.|.| . | | .| .| | . .. . || . | .| | |. .|||. |. | .. .| .| .|
qyypek....eGevltfG....eitvlcseeddkdaniikktlsvrdkdsGkehklkhlkikswpdksval......stlallrtlrilr.......kas
SPLIVHCSAGIGRTGTMIALDHAMCALDMGVKVDVLSIVADIREDRMAMVQHVVQYRYLYQAVVEYA
|..||||||||||||..|.. .. | | ..|.| .| .|. |.. || .|| | ......
GpvvvhcsaGiGrtGtfvaievglqilldGkeldlldlvralrnsrlnsvqvdiqylalveilldlG
|
|||||||||
| subfamily_ptpA1_pd | Subfamily ptpA1 | 737-962 | 2.4e-26 | 87.4 | In-house | 49-258 (418) | alignment | ||
Range on Protein: 737-962
Range on HMM: 49-258/418.0
RLNRFRDILPNPVTRVRLEPLEVDHTLEYINANYVrdpsapcDnkpallgfgGRRAKEYVAAQAPKDTGLFNFWRMIVHVQARCIAMTTGLVEGGKNKCS
||. .||| |||.|. .. .||||||. | | |.....| | . .||||. ..| | | . | . ||
sknrytnilpvnhtrvqlkkiqdkegsdyinanyi.......d.........gaypkqfictqgplpntiadfwrmvwenrcriivmlsresencrikcd
RYWPATIYAETKEelVYGPRD---GKIHVRTMLVT--KMEGYIKTNIQVLYQGSTRNLVHFWFTAWPDHGVPtrpDgsmQTQQMIEMLLDIRRTRNEL--
|||| | | .|| . | | . | | ||.. ..| ||.. .. . |||| .| | .|| . ..| | .|..
rywpeqiggeqfs..iygngnevfgtysvelveviqdpereiitrnirltfegetrditqyqyegwpdhnip...d...htqpfrqllhsitnrqnqiip
-DRAESPLIVHCSAGIGRTGTMIALDHAMCALDM
. |.|||||||.|||||. . | ||
ssdrnvpiivhcsagvgrtgtfctavimmkkldh
|
|||||||||
| Y_phosphatase | Protein-tyrosine phosphatase | 738-998 | 3.5e-55 | 182.4 | Pfam-A | 4-235 (235) | alignment | ||
Range on Protein: 738-998
Range on HMM: 4-235/235.0
LNRFRDILPNPVTRVRLEPLEVDHTleYINANYVrdpsapcdnkpallgFGGRRAKEYVAAQAPKDTGLFNFWRMIVHVQARCIAMTTGLVEGGKNKCSR
||..|||| |||.|. | .. ||||||| | .. |...|.|.| . . ||||... . ..|.| | |.| |..||..
knRykdilpydktrvklkgsegpsd..YInAnyv...............kgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaq
YWPatiyAETKEELVYgprdGKIHVRTM-LVT-KMEGYIKTNIQVLYQGST---RNLVHFWFTAWPDHGVPTRpdgsmqTQQMIEMLLDIRRTRnelDRA
||| |..|.| | |.|.|... .. ....|. ..... ... | . ....|.|||||||. ........ ...... .
Ywp....eeeeeslty....gdikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpes......pkslldlirkveksk...eak
ESPLIVHCSAGIGRTGTMIALDHAMCALDMGVKVDVLSIVADIREDRMAMVQHVVQYRYLYQAVVE
..|..||||||.|||||..||| ... |. . .||||.|| .|. |. ||| . || .||.|..|
sgpvvVhCsaGvgRtgtfvaldilleqleaeeevdvlqivkelRkqRpgmvqsleqYiflykaile
|
|||||||||
| Y_phosphatase | Protein-tyrosine phosphatase | 738-998 | 3.5e-55 | 182.4 | In-house | 4-235 (235) | alignment | ||
Range on Protein: 738-998
Range on HMM: 4-235/235.0
LNRFRDILPNPVTRVRLEPLEVDHTleYINANYVrdpsapcdnkpallgFGGRRAKEYVAAQAPKDTGLFNFWRMIVHVQARCIAMTTGLVEGGKNKCSR
||..|||| |||.|. | .. ||||||| | .. |...|.|.| . . ||||... . ..|.| | |.| |..||..
knRykdilpydktrvklkgsegpsd..YInAnyv...............kgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaq
YWPatiyAETKEELVYgprdGKIHVRTM-LVT-KMEGYIKTNIQVLYQGST---RNLVHFWFTAWPDHGVPTRpdgsmqTQQMIEMLLDIRRTRnelDRA
||| |..|.| | |.|.|... .. ....|. ..... ... | . ....|.|||||||. ........ ...... .
Ywp....eeeeeslty....gdikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpes......pkslldlirkveksk...eak
ESPLIVHCSAGIGRTGTMIALDHAMCALDMGVKVDVLSIVADIREDRMAMVQHVVQYRYLYQAVVE
..|..||||||.|||||..||| ... |. . .||||.|| .|. |. ||| . || .||.|..|
sgpvvVhCsaGvgRtgtfvaldilleqleaeeevdvlqivkelRkqRpgmvqsleqYiflykaile
|
|||||||||
| subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 738-1021 | 2.1e-51 | 169.9 | In-house | 49-301 (318) | alignment | ||
Range on Protein: 738-1021
Range on HMM: 49-301/318.0
LNRFRDILPNPVTRVRLEPLEVDHTLEYINANYVRdpsapcdnkpallgfGGRRAKEYVAAQAPKDTGLFNFWRMIVHVQARCIAMTTGLVEGGKNKCSR
||. .||. |||.|..||.... .||||||. | || |.|.||||| . .||||. ... | | | ..| ||.|. |
knryanilaydhtrvkLqmlegeegsDyinanyid...............GyrrkkayiaaqaPlpetieDfWrmvWeqnsavivmltqeeergkakvhr
YWPAtiyaetKEELVYgprdGKIHVRTMLVTKMEGYIKTNIQVLYQG--STRNLVHFWFTAWPDHGVPTRPdgsmqtQQMIEMLLDIRRTRNelDRAESP
||| |. | ||..| . .... |. ...| .. ..|. . .|.|||.|||. . ...... ..... . . ..|
yWPs......kgsrsy....gklvvelkeevelsdyvlrefkvtrteeeesrqvrqyhytsWpdegvpesg......aslldlvrqvskaqq..ksgagp
LIVHCSAGIGRTGTMIALDHAMCALDMGVKVDVLSIVADIREDRMAMVQHVVQYRYLYQAVVEYAERLAAREQEEEAAQAYEQMRE
..||||||.||||. ||.| . . |||. .| .|| | .||| || ..|....|. . . . .. .. ...||
ivvhCsaGvGrtGvfiavdillerikaealvDvfqtvkqlreqrnlmvqtedqyefiydvllealasgdtevdasdlrsrirelre
|
|||||||||
| subfamily_PTPN3_pd | Subfamily PTPN3 | 738-999 | 3.6e-51 | 168.7 | In-house | 44-274 (280) | alignment | ||
Range on Protein: 738-999
Range on HMM: 44-274/280.0
LNRFRDILPNPVTRVRLEPLEVdhtlEYINANYVRDPSaPcdnkpallgfGGRRAKEYVAAQAPKDTGLFNFWRMIVHVQARCIAMTTGLVEGGKNKCSR
||.||||| |||.|. |. .||||||| . | . . |.|.| | .. .||.|. . ... | | | ||| |. || .
knryrdilpydatrvklkeset....dyinanyvnmei.p..........stglvnryiatqGPlaktatdfWqmvweqksslivmlttlverGrvkChq
YWPAtiyaeTKEELVYGprdgKIHVRTMLVTKMEGYIKTNIQVLYQG--STRNLVHFWFTAWPDHGVPTRPdgsmqtQQMIEMLLDIRRTRnelDRAESP
||| |..|| || ...|. . . |. .. . . |..... ..||||||||. . ....|.. .|..| .|.|
yWPe.....tedeleyg....efsvkcekedetksyvlrelvlkdketkeerkilqlqylaWpdhgvPdds......adflefvervrklr...sgkeeP
LIVHCSAGIGRTGTMIALDHAMCALDMGVKVDVLSIVADIREDRMAMVQHVVQYRYLYQAVVEY
..||||||||||| .|.|. |.. ... .| .| || .|. |...|| . ||... .|...
vvvhCsaGigrtGvlilletalalieaaepvypldivrtmrdqramlvqtasqykfvCeailkv
|
|||||||||
| subfamily_PTPN14_pd | Subfamily PTPN14 | 738-1001 | 1e-47 | 157.6 | In-house | 52-297 (300) | alignment | ||
Range on Protein: 738-1001
Range on HMM: 52-297/300.0
LNRFRDILPNPVTRVRLEPLEVDhTLEYINANYVRDPSapcdnkpallgfgGRRAKEYVAAQAPKDTGLFNFWRMIVHVQARCIAMTTGLVEGGKNKCSR
|||.|.|| .||.| | . . . .|||| .. . | . ..|..||.| .. . .||.|. . . |.| | |.||.|. .
knrfkdvlPyednrvelsptken.stgyinassikvsv.............ggkersyivaqgPleltvqdfWqmvWeqgvqlivmlteeeedgkeksfk
YWPATiyAETKEELVYGprdgKIHVRTMLVTKMEGYIKTNIQVLY--QGSTRNLVHFWFTAWPDHGVPTRPDGSMQTQQMIEMLLDIRRTRNELDRAESP
|.| . . |... .| | .| | .... . .| | ... . . |...|. .| ||||||| ..| .. .... . . .| .. |
yfPkl..eskkktvefg....kfkvttkfsedsdsvittglklkhlpskeertvwhlqytDWpdhgvPeDvkgflsyLeevqsvrrktnseveskeskPP
LIVHCSAGIGRTGTMIALDHAMCALDMGVKVDVLSIVADIREDRMAMVQHVVQYRYLYQAVVEYAE
..||||||.|||| .| | . .|. . ..|. ...| .|| || .|| . ||...|.....| .
vlvhCsaGvGrtGvlilsdlliatlehneeidikkvlarLreqrmllvqtlaqYkfvYkvlikylk
|
|||||||||
| subfamily_PTPRA_pd | Subfamily PTPRA | 738-999 | 4.9e-46 | 152.1 | In-house | 61-294 (330) | alignment | ||
Range on Protein: 738-999
Range on HMM: 61-294/330.0
LNRFRDILPNPVTRVRLEPLEVDHTLEYINANYVRdpsapcdnkpallgfGGRRAKEYVAAQAPKDTGLFNFWRMIVHVQARCIAMTTGLVEGGKNKCSR
||. .|||. .|| | ..| .. .|||| .. | .. ....||| ||. . .||||| .. | | | | | ..|| .
knrvvnilPydfsrvilsvkeGveesdyinasfid...............GykekdkfiaaqGPkeetvedfwrmiweqksativmltelkerkeekcaq
YWPAT---IYAETKEELVYGPRDGKIHVRTMLVTKMEGYIKtniqvlyQGSTRNLVHFWFTAWPDHGVPTRPDGsmqtqqMIEMLLDIRRTRNEldRAEs
||| | . . |. .. || .||... . . ..| . | ||.||| |||. | | |...| ...... |.
ywPdeGlvtyGnirvevedetvlvdytvrkflvqqlpdatr.......ekksrlvrqfhftswPdvGvPfepiG......mlkllkkvkklnqq..sag.
PLIVHCSAGIGRTGTMIALDHAMCALDMGVKVDVLSIVADIREDRMAMVQHVVQYRYLYQAVVEY
|..||||||.|||||.|.|| . . |||| .| .| | ||| || ..|... ||
pivvhcsaGvGrtGtfivldavlervkaerkvdvfefvkrlrlqrpqmvqtdeqyefiykvlley
|
|||||||||
| subfamily_PTPRK_pd | Subfamily PTPRK | 738-998 | 1.9e-44 | 146.7 | In-house | 46-275 (314) | alignment | ||
Range on Protein: 738-998
Range on HMM: 46-275/314.0
LNRFRDILPNPVTRVRLEPLEVDHTLEYINANYVrdpsapcdnkpallgFGGRRAKEYVAAQAPKDTGLFNFWRMIVHVQARCIAMTTGLVEGGKNKCSR
||. |||. .||.| ... | .||||... . .|.......| |.. . .|||.. . .. .| | | ||| |. ||..
knrsgdilaydrsrvflitidgdpssdyinaali...............dsykrpaafivtqgPlqetvkdfWrlvydencasivmltelvevgrvkClk
YWPA--TIYAETKEELVYGPRDGKIHVRTMLVTKmegyiktnIQVLYQgSTRNLVHFWFTAWPDHGVPTrpdgsmQTQQMIEMLLDIRRTRNEldrAESP
||| ..| . | ||| . .. ||.. |.| .. .. .| . .| |..||||.||. . . ..... . ...| . .
yWPedtevygdikvelvetellaelvvrifrvek........largqe.eirevrqfqflgWpdhdvPv......satgllklvrrvkksqee...eaGr
LIVHCSAGIGRTGTMIALDHAMCALDMGVKVDVLSIVADIREDRMAMVQHVVQYRYLYQAVVE
..|||||| ||||| ||.| . .. ||| .| ..|. .. ||. ||...|....|
ivvhCsaGaGrtGtfiaidivldmieregvvdvfnavktlrsrkvnmveteeqykfiydvile
|
|||||||||
| subfamily_PTPRG_pd | Subfamily PTPRG | 738-1012 | 8.4e-41 | 134.8 | In-house | 50-296 (563) | alignment | ||
Range on Protein: 738-1012
Range on HMM: 50-296/563.0
LNRFRDILPNPVTRVRLEPLE-VDHTLEYINANYVRdpsapcdnkpallgfGGRRAKEYVAAQAPKDTGLFNFWRMIVHVQARCIAMTTGLVEGGKNKCS
|| .|.. .||.|.|| ....|.||||||. | ...|...|.| | . . ||||| .. | | | ||| |..||
KnRylnivaydrsRvklsplpgkkkklDYinAnyid...............GyqkskafiatqgplkdtfddFWrmiWeqnvaiivmitnlvergrrkcd
RYWPAtIYAETKEELVYG-PRDGKIHVRTMLVTKMEGY-IKTNIQvlyQGSTRNLVHFWFTAWPDHGVPTRPdgsmqtqqmIEMLLDIRRTRNELDRAES
.|||. .|| ..| . .. . |. ... .| . | . . .. .. .| |||||||. . . | ... ..
vYWPk.desetygalqvtlieeevlalytvrtlviknlklkkkkq...cdteklvrqyhytkWPdhgvPehs.........lpvLifvkkssaankaeaG
PLIVHCSAGIGRTGTMIALDHAMCALDMGVKVDVLSIVADIREDRMAMVQHVVQYRYLYQAVVEYaerLAAREQEEEA
|..||||||.||||| |.|| . . .|.|. .. || | .|| || .|..|..| .|..|.| |
PivvHcsaGvgrtGtyivldtllkqiqqenavnvfgflkhiraqRnflvqteEqYiflhdallea...iasketella
|
|||||||||
| subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 738-1001 | 1.1e-36 | 121.3 | In-house | 50-279 (287) | alignment | ||
Range on Protein: 738-1001
Range on HMM: 50-279/287.0
LNRFRDILPNPVTRVRLEplevDHTLEYINANYVRdpsapcdnkpallgfGGRRAKEYVAAQAPKDTGLFNFWRMIVHVQARCIAMTTGLVEGGKNKCSR
.||...||. || |. .. .|||| .. | . .|....|..| . |||..| . . | | . . | ...| .
knRltqilvpdnyrvllk....gehpdyinavfid...............gykekkafiiaesPmfntarnfWkliddrnvtaivmlcqekendeevcyq
YWPATiyaetKEeLVYGPRdgkiHVRTMLVTKMEGYIKTNIQVLYQG---STRNLVHFWFTAWPDHGvptrpdgSMQTQQMIEMLLDiRRTRNELDRAES
||| . | .|.|. ... . ....|||. ...| .. ...... . .|.|...| ....| | .... .. ... |...
yWpee.....ks.vvlGey....niellneevnagyierklevknknkagdkqqvkqyqitnWdstg.......kvtepqtillvie.emyktqrkrgnt
PLIVHCSAGIGRTGTMIALDHAMCALDMGVKVDVLSIVADIREDRMAMVQHVVQYRYLYQAVVEYAE
...||||...||.....| . .. . .||.... | .. .|| | ||......|.|| .
sivvhCsdtvGrsamfcaaattinkckteGviDvfqvlksqriqkpgsvqtveqykfindivleyld
|
|||||||||
| 0041856 | (Phosphotyrosine protein) phosphatases II | 738-1000 | 3.6e-34 | 113.3 | In-house | 4-171 (182) | alignment | ||
Range on Protein: 738-1000
Range on HMM: 4-171/182.0
LNRFRDILPNPVTRvrleplevdhTLEYINANYVRdpsapcdnkpallgfGGRRAKEYVAAQAPKDTGLFNFWRMIVHVQARCIAMTTglveggknkCSR
.||..||||.. .| | |||||... |...|....|.|.| . . .|.||. . . ..| . | . .
knrysdilpydhsr..........dldyInanlyl...............gslpatrfiatqgpllstvadflrmlkelgittivnlt.........eel
YWPatiyaetkeelvygprdgkihvrtmlvtkmegyiktniqvlyQGSTRNLVHFWFTAWPDHGVPTrpdgsmqTQQMIEMLLDIRRtrneldrAESPLI
||| . .|. ...... |||||||. ........ .... . | .
ywp..........................................ellerlgiqylylpwpDhgvpd.......ldelldfieevle.......eggpvl
VHCSAGIGRTGTMIALDHAMCAldmgvKVDVLSIVADIREDRMAMVQHVVQYRYLYQAVVEYA
||||||.|||||..|.. .. .|.. ..|. .|. |. ||.. ||..|..|. |.
VHCsaGvgRtgtlvaaylmkkl.....gvsleeavklvrsrRpgmvitpnqyfflqlallell
|
|||||||||
| subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 738-1000 | 9e-34 | 111.5 | In-house | 41-277 (287) | alignment | ||
Range on Protein: 738-1000
Range on HMM: 41-277/287.0
LNRFRDILPNPVTRVRLEpLEVDHTLEYINANYVrdpsaPcdnkpallGFggRRAKEYVAAQAPKDTGLFNFWRMIVHVQARCIAMTTGLVEGGKNKCSR
||. |.|| ||| | | .. .||||||| . .. .. ....|||.| . . .|||.... .. ... | || ...|| .
knryadvlPiddtrvlls.aegelGsdyinanyv.....a........sy..tddeafiaaqgPiaatvrdfwravletrsasvitmtreveearlkcyk
YWPatiyaETKEELVYGprDGKIHVRTMLVTKMEgYIKTNIQVLyQGSTRN--LVH-FWFTAWPDHGVPTRPDGSMQTQQMIEMLLDIRRTRNELdraeS
||| | . . | . . . . | | .... . ||. .|. . . .|||.... | .. .. ....| .|
ywP.....erevPmrvG..GysvvlldydikePe.ygvralrli.dletrearvvkqldllswPdkvlaPtavglirfvldvkqhielardasev....G
PLIVHCSAGIGRTGTMIALDHAMCALDMGVKVDVLSIVADIREDRMAMVQHVVQYRYLYQAVVEYA
||.||...||||.|...|. . | .||| .|. .|| | |.|| |||.|.||.|.| |
PlvvhddvGiGrsGillatlvlvsrledlGrvdvaavvirlreyraalvqavvqlrllyealvtyy
|
|||||||||
| subfamily_Cele-PTP-18_pd | Subfamily Cele-PTP-18 | 738-1007 | 2.6e-28 | 93.6 | In-house | 51-294 (305) | alignment | ||
Range on Protein: 738-1007
Range on HMM: 51-294/305.0
LNRFRDILPNPVTRVRLEPlevDHTLEYINANYVRDPSAPcdnkpallgfggrraKEYVAAQAPKDTGLFNFWRMIVHVQARCIAMTTGLVEGGKNKCSR
||..|. ||.||. ||| |||| |. | | .. .||| . .|| | . . | | |.| | .||.
knrykdvgcldnnrvkleg...pwpheyihanyvstptnp...............krfictqaplektcadfwymclqdkveaifmlcnllekgakkcle
YWPAtiyaETKEELVYGPRDGKIHVRTMLVTKMEGY------I-KTNIQVLYQG-STRNLVHFWFTAWPDHGVPTRpDgsmqtQQMIEMLLDIRRTRnel
|... . |..| . .. || |. .... . .| . . | ..| |. . ||| |||. | . ..|.| . | ..
yfas....kdkdvlefeekgqkisvkfessvtlkfrkdakakvtetvlviegpgekarkvthyhwidwpdrgvpaa.d.....lailellekarpsk...
draeSPLIVHCSAGIGRTGTMIALDHAMCALDMGVKVD-VLSIVADIREDRMAMVQHVVQYRYLYQAVVEYAERLAARE
|..|||||||||||... |.. . | | ... |. |||.| .| || ...| ...| .. .
....gpivvhcsagigrtgsvvmleyildqllagqiiedtdkilqkireqrnnsiqtdaqylfvhqvilnyfrkkklld
|
|||||||||
| subfamily_Cele-PTP-13_pd | Subfamily Cele-PTP-13 | 738-1000 | 8.9e-25 | 81.9 | In-house | 40-269 (281) | alignment | ||
Range on Protein: 738-1000
Range on HMM: 40-269/281.0
LNRFRDILPNPVTRVRLEP-LEVDHTLEYINANYVRDPsapcdnkpaLLgfggrrAKEYVAAQAPKDTGLFNFWRMIVHVQARCIAMTTGLVEGGKNKCS
||. .| ..||.|. . . .|| |||.| | .| . |. .| || .||||| . .. .| | ..| ..||.
knrylnipcldisrvqlkvkmpnknstdyihanyirsp.........fl......krgyiltqgpkketradfwrmiwqenttaivmlcqfletnrekca
RYWPATIYAETKeelvYgprdGKIHVRTMLVTKMEGYIKTNIQVLYQGSTRNLVHFWFTAWPDHGVPTrpdgSmqTQQMIEMLLDIRRtrneldRAeSPL
|.| .. . . |. | | . . | ... |.| || . |. . ||| || | .. |...| || |. .|
eyfprnahcclq....f....dklsvsyedstvnkslvttrlnlsyegetrlithwlwkewpdwqvpe....s..sevmlkilrkira......rs.tpp
IVHCSAGIGRTGTMIALDHAMCALDMGVK-VDVLSIVADIRE-DRMAMVQHVVQYRYLYQAVVEYA
..|||||.||.||..|.. |. .. . |. ||. .| | | || . || ... ....
vihcsagvgrsgtlmaveialqsihshftlpdikqivshlrvtgraasvqtlqqymliwkvlldfg
|
|||||||||
| subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 738-1003 | 4.1e-16 | 53.8 | In-house | 36-262 (267) | alignment | ||
Range on Protein: 738-1003
Range on HMM: 36-262/267.0
LNRFRDILPNPVTRVRLEPLEVDhtleYINANYVRdpsapcdnkpallgfGGRRAKEYVAAQAPKDTGLFNFWRMIVHVQARCIAMttgLVEGGKNKCSR
||. | || ||| | | . |||| || | .. . ... | | . .|. .| . . | . | .... .
rnrlddnlpyddtrvilrtkeee....yinasyve...............gyktknafivtqdplkntitdfltvihdqkvpvivl...ltkvftdnirl
YWPATIYAETKeelvYgpRdgKIHVRTMLVTKMEGYIKTNIQVLY-QGSTRNLVHFWFTAWpdhGVPTrpdgsmQTQQMIEMLLDIRrTRNELDRAESPL
.|| . | | . . | | . . | ... . . |..|.. ... | . | . . .. |. | ..|.|. .. ||
fwPPkmgqakk....y..q..dltvehslekeendyqiitlelkfknesahnvtlyyykkw...nint......nnkpylkplfgil.aknqlengnrPl
IVHCSAGIGRTGTMIALDHAMCALDMGVKVDVLSIVADIREDRMAMVQHVVQYRYLYQAVVEYAERL
.|.||.|.||.||.. .| . . .|. . ||. |...|. .| |... ..||||
vvacsdGvGrsGtflvidsqleraktegvsdifdflrkirsqriglvdtkeryiyihellaeyaegr
|
|||||||||
| subfamily_PTPN6_pd | Subfamily PTPN6 | 739-1005 | 2.9e-56 | 185.7 | In-house | 58-300 (306) | alignment | ||
Range on Protein: 739-1005
Range on HMM: 58-300/306.0
NRFRDILPNPVTRVRLEpLEVDHTLEYINANYVRdPSAPCDNkpallgfggrraKEYVAAQAPKDTGLFNFWRMIVHVQARCIAMTTGLVEGGKNKCSRY
||.. ||| ||| |. . .||||||.. ... . |.|.|.| .| . .||||.. ..| | ||| || ||.||.||
nryknilPfDhtrvilk.epsvpgsdyinanyik.kevkgsd............ksyiatqgclettvsdFWrmvwqensrvivmttkevErgkekCarY
WPATiyaETKEElvYgprdGKIHVRTMLVTKMEGYIKTNIQVL---YQGSTRNLVHFWFTAWPDHGVPTRPdgsmqtQQMIEMLLDIRRTRNELD-RAES
||.. |.||| | |||.|... .... || ...| ....|..... |..|||||||. | ......| |..| ..|| . .
WPde...eekee..y....GkisvtnvseksladYilRelsvskkkkkkeerevfqyhfksWPdhgvpkdp......gavLdfledvnrkqeeleeaeag
PLIVHCSAGIGRTGTMIALDHAMC---ALDMGVKVDVLSIVADIREDRMAMVQHVVQYRYLYQAVVEYAERlaA
|..||||||||||||.| .| . . ...|. ..| .|| | .|| ||...|.|. .| |.
pivvhCsaGiGRtGtfiviDillkliekkgldadidiqklvksvreqrsglvqteqqykfvykaikkyiet..k
|
|||||||||
| subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 739-1000 | 5.3e-46 | 151.8 | In-house | 47-276 (515) | alignment | ||
Range on Protein: 739-1000
Range on HMM: 47-276/515.0
NRFRDILPNPVTRVRLEPLEVDHTLEYINANYVrdPSAPCDnkpallgfggrraKEYVAAQAPKDTGLFNFWRMIVHVQARCIAMTTGLVEGGKNKCSRY
||...||| .||.|| .. . .|.|| |. || .| | |.|.|.|... . .|||.... . ||| | | || | ||..|
nryknilPydsvrvklevindnPhsdyfnasyi..psfdnd.............kayiasqgPnkasvddfWrlvlqenvttiamvtklkegdkikcgky
WPATIyAETkeeLvygpRDGKIHVRTMLVTKMEGYIKTNIQVLYQGSTRNLVHFWFTAWPDHGVPTRpdgsmqTQQMIEMlldIRRTRNELDRAESPLIV
|| ... . . |.|.| .. . | || ...|| . .| . | || |||.||| . |. .. . |. . . .. . |||.
WPdkp.gds...v....kfGsikvelvsleactggikrkltvlkgddsrtvtqfhfteWPdkGvpkh......tssllkl...ikevkadhgqythplii
HCSAGIGRTGTMIALDHAMCALDMGVKVDVLSIVADIREDRMAMVQHVVQYRYLYQAVVEYA
|||||.|||| .|..| . . |||. .| ||..|. .|| || ..|.|| |.
hcsaGvGrtGvvisidsvvahakttrmvdvfnfvtnirqkrpylvqtqeqyafiygavledl
|
|||||||||
| subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 739-998 | 4.7e-44 | 146.0 | In-house | 65-289 (319) | alignment | ||
Range on Protein: 739-998
Range on HMM: 65-289/319.0
NRFRDILPNPVTRVRLEPLEVDHTLEYINANYVRdpsapcdnkpallgfGGRRAKEYVAAQAPKDTGLFNFWRMIVHVQARCIAMTTglveggKNKCSRY
||. .||. ..|.||.|. .|||| .| | .| . |.||| |.| | .||||| .. | . | |.|||.|
nriinilafdknvvklerliGeefsdyinasfvt...............GyqrkdkyiaaqGPldntladfWrmiweyncstivllt......kdkcsqy
WPATIYAetKEelvygprdGKIHVRTMLVTKMEGYIKTNIQVLYQG---STRNLVHFWFTAWPDHGVPTRPDGSMQtqqMIEmllDIRRTRNElDRAESP
|| | || .. .|. .|.. . |. .|.. .| |.. | | |||.||| | |. ... .| .. . . .
wplkivi..ke........erfkvkvdsveetaeyvvrdielsedgkekdirkitqfhflGwpdvGvpdypsdlmr...lvk...kvrhltsk.enhran
LIVHCSAGIGRTGTMIALDHAMCALDMGVKVDVLSIVADIREDRMAMVQHVVQYRYLYQAVVE
..||||||.||||. |.|| . .. .||| .| |.|..| .||..||| ..| |..|
ivvhcsaGvGrtGvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysalle
|
|||||||||
| subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 739-1000 | 1.6e-43 | 144.0 | In-house | 55-284 (297) | alignment | ||
Range on Protein: 739-1000
Range on HMM: 55-284/297.0
NRFRDILPNPVTRVRLEPLEVDHTLEYINANYVRdpsapcD--NkpallgfggrrakEYVAAQAPKDTGLFNFWRMIVHVQARCIAMTTGLVEGGKnKCS
.|...||| . ||.|. .. | .|.|| .|. . .... | |... . .||.|... |. |.| . . |. | ||
sRYkniLPydssRvkLaivnddpdsDyvnasfvk......gnkh.............rlittqmPmkatvadfWamvldeqvstivmlnddnerdk.kca
RYWPATIYAEtkeelvygprDGKIHVRTMLVTKMEGYIKTNIQVLYQG--STRNLVHFWFTAWPDHGVPTRPdgsmQTQQMIEMLLDIRRTRNelDRAES
|||. . .. |.. | .. |.. ||.|| ...| . ..| . . |. |||. |. . ......... ..| . . ..||.
ryWsdkgvtt..........fGdvsvvllsvsereGfikrelevtkgkakarrvvkqyqfveWPdkaverkd....sassllklisevrkdfs..qnaeg
PLIVHCSAGIGRTGTMIALDHAMCALDMGVKVDVLSIVADIREDRMAMVQHVVQYRYLYQAVVEYA
||.|||.||.|||| ....| .. .||.. .| .|..|. .|| ||...|.||.|.
PllvhclaGvGrtgvlltidsvvaeakrekevdifglvkklrqerpylvqtkeqykfvyvavleal
|
|||||||||
| subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 739-998 | 2.1e-43 | 143.8 | In-house | 29-253 (284) | alignment | ||
Range on Protein: 739-998
Range on HMM: 29-253/284.0
NRFRDILPNPVTRVRLEPLEVDHTLEYINANYVRdpsapcdnkpallgfGGRRAKEYVAAQAPKDTGLFNFWRMIVHVQARCIAMTTglveggKNKCSRY
||. .||. ..|.||.| .|||| .. | .| . |.|.| |.| | .||||| .. | . | |.|||.|
nrighilafdknvvklerliGeefsdyinasfit...............GyqrkdkyiatqGPldntladfWrmiweyncstivllt......kdkcsqy
WPATIYAetKEelvygprdGKIHVRTMLVTKMEGYIKTNIQVLYQG---STRNLVHFWFTAWPDHGVPTRPDGSMQtqqMIEmllDIRRTRNElDRAESP
|| | || .. .|. .|.. | |. .|.. .| |.. | | |||.||| | |. ... .| .. . ...
wplkivi..ke........erfkvkvdsveeseeyvvrdielsedgkekdirkirqfhflgwpdvgvpdypsdlmr...lvk...kvrhltsk.enhran
LIVHCSAGIGRTGTMIALDHAMCALDMGVKVDVLSIVADIREDRMAMVQHVVQYRYLYQAVVE
..||||||.||||..|.|| . .. .||| .| |.|..| .||..||| ..| |..|
ivvhcsagvgrtgvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysalle
|
|||||||||
| subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 739-1001 | 1.4e-41 | 137.3 | In-house | 13-243 (250) | alignment | ||
Range on Protein: 739-1001
Range on HMM: 13-243/250.0
NRFRDILPNPVTRVRLEPLEVDHTLEYINANYVRdpsapcdnkpallGFGGRraKEYVAAQAPKDTGLFNFWRMIVHVQARCIAMTTGLVEGGKNkCSRY
||. ||.. .|| ||. . |. .|||| .. |. .| | ..|.|.| . . .||||... .. | | | |.| .|. ...|
nryadiialdssrvvLekekgdkesdyinasflh.............gyder..kafiatqgPlqatiedfWrmvleeksgtivmLtnLkesekt.yhqy
WPAtiyaETKEElvYgprdGKIHVRTMLVTKMEGYIKTNIQVLYQGS--TRNLVHFWFTAWPDHGVPTrpdgsmQTQQMIEMLLDIRRTRNELDraESPL
||. |. |. | |...| . .. |.|..... . | .... |..||| ||| ... ..|.| ........ . ..|.
wPv....ekaek..y....GdvtvsllskeefadytkrklklskakkaderivrqlhfvvWPdkgvPe......vatavLellkkvqasqqqag..naPv
IVHCSAGIGRTGTMIALDHAMCALDMGVKVDVLSIVADIREDRMAMVQHVVQYRYLYQAVVEYAE
||.||||.||.|. ||.| . | .||| .. .|.||. .|. || ..|... .. .
ivqCsaGvgrsGafiaidavlerlkkekvvdvfkvikvlrkdrphavesleqyvfvyeiilkald
|
|||||||||
| subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 739-1000 | 7.2e-40 | 132.1 | In-house | 52-288 (325) | alignment | ||
Range on Protein: 739-1000
Range on HMM: 52-288/325.0
NRFRDILPNPVTRVRLEPLEVDHTLEYINANYVRDpsapcdnkpallgFggRRAKEYVAAQAPKDTGLFNFWRMIVHVQARCIAMTTgLVEGGKNKCSRY
|||..... .|| || .. | .||||.|.|| . .. . ..|||||. . . ..||... .. . .. ...||..|. |
nrfknvvaldksrvvletkkddpssdyinasylrd.............d..kkkdvflaaqaPltatindlWrlvldWrcsvvvvln.eldlgkdrcavy
WPATIyaetKEELVYGPrdgkIHVRTMLVTKMEGYIKT--NIQVLYQGSTRNLVHFWFTAWPDHGVPTRPDGSMQTQQMIEMLLDIRRTRnelDRAESPL
|| . . .|. ..|. . . .. |.. ... .| || . | . .|.| ||. || . |... . . .. .| .|.
wpkem....gksktfGg....levklrtieeisdyvhrvldvkqvkkGetrsvkqfqlqswddmGvqkrpatlisilqlvkavservtan...tkastpi
IVHCSAGIGRTGTMIALDHAMCALDMGVKVDVLSIVADIREDRMAMVQHVVQYRYLYQAVVEYA
.||||||.||||..|.| |. . .||.. | .|.|| .||. | || .|.|.||.
lvhcsaGvGrtGvfislysalakvieesrvdifgfvkklrkdrpsmvetvdqyiliyealveay
|
|||||||||
| subfamily_Sponge-PTP6_pd | Subfamily Sponge-PTP6 | 739-998 | 6.3e-33 | 108.9 | In-house | 52-277 (439) | alignment | ||
Range on Protein: 739-998
Range on HMM: 52-277/439.0
NRFRDILPNPVTRVRL-EPLEVDHTlEYINANYVRdpsapcdnkpallgfGGRRAKEYVAAQAPKDTGLFNFWRMIVHVQARCIAMTTGLVEGGKnkcsr
||..|. . ||| | | | |. ||||||.. | | |.|.|.||. .|||.... .. | | | ||| |
nrykdvgafdhtrvtlqeipgvphs.hyinanyik...............Gyyddklyiatqgpkkettddfwrlviekktvtivmltnlvesyk.....
YWPatiyaeTKEELVYGprdgKIHVRTMLVTKMEGYIKTNIQVLYQG----STRNLVHFWFTAWPDHGVPTrpdgsmQTQQMIEMLLDIRRTRNEldRAE
||| ...| .|| | ||. .. |. ..|. . | ...| ..||||. ||. |. ....| | . .. .
ywp......sdaevcyg....diavrvdrnielpnyvirgfkvfnerdttekertvlqfhyiawpdknvpa......qashvldflrainsandk..eey
SPLIVHCSAGIGRTGTMIALDHAMCALDMGVKVDVLSIVADIREDRMAMVQHVVQYRYLYQAVVE
|..||||||.|||||.|||| |. | . |||. || .|..| |||...|| ..|.||.|
gpvvvhcsagvGrtGtiialdialeqlklenkvdikgivkvlrkqrkqmvqalcqyvfiynavle
|
|||||||||
| subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 739-998 | 1.3e-31 | 104.6 | In-house | 11-238 (239) | alignment | ||
Range on Protein: 739-998
Range on HMM: 11-238/239.0
NRFRDILPNPVTRVRLEPLEVDHTLEYINANYVRDpsapCDNKPallgfggrraKEYVAAQAPKDTGLFNFWRMIVHVQARCIAMTTGLVEGGKNKCSRY
||. .|. .|| || | | .||||.|.|| | | | |.|.| . .||||. . . | | |||.|| |.|| .|
nryanivtydhsrvvleklsndphsdyinasylrd....ydgsp..........kayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqy
WPATIYAETkeELVYGPRDGKIHVRTMLVTkmegYIKTniqVLYQGSTRNLVHFWFTAWPDHGVPtrpdgsmqtqQMIEMLLDI--RRTRNELDRAeSPL
|| . .| | .. .. | .. . . | | . .. || |||.||| | .| . . |.. | | |
wpdstskyc..nlrvtlrktevfadyiirt....fvms...qvgqteeryvyqyhftvwpdkgvp..........qyatavlglrrkitkdslpga.rpw
IVHCSAGIGRTGTMIALDHAMCALDMGVKVDVLSIVADIREDRMAMVQHVVQYRYLYQAVVE
..|||||.||||... .| . ||.. | ||||| ||| || ... ||.|
vihcsagvgrtgaflvidamlrqakkqktvdifnyvkairedrphmvqtseqyvfihlavle
|
|||||||||
| subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 739-998 | 1.7e-31 | 104.2 | In-house | 12-239 (239) | alignment | ||
Range on Protein: 739-998
Range on HMM: 12-239/239.0
NRFRDILPNPVTRVRLEPLEVDHTLEYINANYVRDpsapCDNKPallgfggrraKEYVAAQAPKDTGLFNFWRMIVHVQARCIAMTTGLVEGGKNKCSRY
||. .|. .|| || | | .||||.|.|| | | | |.|.| . .||||. . . | | |||.|| |.|| .|
nryanivtydhsrvvleklsndphsdyinasylrd....ydgsp..........kayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqy
WPATIYAETkeELVYGPRDGKIHVRTMLVTkmegYIKTniqVLYQGSTRNLVHFWFTAWPDHGVPtrpdgsmqtqQMIEMLLDI--RRTRNELDRAeSPL
|| . .| | .. .. | .. . . | | . .. || |||.||| | .| . . |.. | | |
wpdstskyc..nlrvtlrktevfadyiirt....fvms...qvgqteeryvyqyhftvwpdkgvp..........qyatavlglrrkitkdslpga.rpw
IVHCSAGIGRTGTMIALDHAMCALDMGVKVDVLSIVADIREDRMAMVQHVVQYRYLYQAVVE
..|||||.||||... .| . ||.. | ||||| ||| || ... ||.|
vihcsagvgrtgaflvidamlrqakkqktvdifnyvkairedrphmvqtseqyvfihlavle
|
|||||||||
| subfamily_CG7180_pd | Subfamily CG7180 | 739-999 | 4.7e-30 | 99.2 | In-house | 46-289 (296) | alignment | ||
Range on Protein: 739-999
Range on HMM: 46-289/296.0
NRFRDILPNPVTRVRLEPLEVDHTLEYINANYVRdpsapcdnkpallGFggRRAKEYVAAQAPKDTGLFNFWRMIVHVQARCIAMTTGLVEGGKnKCSRY
|| ...| .|| || |. ... .|||| || .| . |||. .|||. . .|||.. .. .. . | . | .. |
nrdvkvvPyDynRvvLekldGeeksdYinavyvd.............sf..lkkkeyivteapkketvdefWrlvydeeisavvvLtktfdfak.mypsy
WPAT---IYAETKEELVYGPRDGKIHVRTMLVTKM-EGYIKTNIQVlyQGSTRNLVHFWFTAWPD-HGVPTRPDGSMQTQQMIEMLldirRTRNELDRAE
|| . | | |.| ... ||. .||. ... || . || . .| .| |. . || . .. ...... | ... | |
wpnkskeqygeifveiveekqyanlkirtfkltkkivalteqekqv..kaetRivklfqlteWeledkvPlstnalielrrrvrlw....rekvdedpee
SPLIVHCSAGIGRTGTMIALDHAMCALDMGVKVDVLSIVADIREDRMAMVQHVVQYRYLYQAVVEY
.|..|..| | .|.| .|.| .. .. .||| | .|..| .|. | .|.|.|. . |.
gPvvvvssdGasRsGvylaidanlelvekeeevdvFeavktlrrsRpqLvenveeYkyiYdvllea
|
|||||||||
| subfamily_CG42327_pd | Subfamily CG42327 | 739-925 | 6.2e-21 | 69.4 | In-house | 32-193 (319) | alignment | ||
Range on Protein: 739-925
Range on HMM: 32-193/319.0
NRFRDILPNPVTRVRLEPLEVDHTLEYINANYVRDPSA-PCdnkpallgfggrrakEYVAAQAPKDTGLFNFWRMIVHVQARCIAMTTGLVEGGKNKCSR
.|. ...| | ||| |. | ||..|.||| . |. |.|||.. . .|||.. |.| | | | | | ..|..
srvinvvPlPetrvvlqrigdddkdeyldasyvrGyddapn...............syiaaqvsledsssdfwrtvweqqsrvivqltdlselGikvcae
YWPATiyAETKEELVYGprdgKIHVRTMLVTKMEGYIK-T-NIQVLYQGSTRNLVHFWFtAWPDHGVPTRPdgsmqtQQMIEMLLDIRRT
|.|. . ... .|| .| | . |. | .. . . .|.| |.|. |.. .||. . . .| |||..| .
ylPtk..etldntslyG....dilvtlkgrevkdryaistlllkrvdkeesrelthywy.kwleaevPaee......aaliamllevrss
|
|||||||||
| subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 739-847 | 4.2e-16 | 53.6 | In-house | 51-158 (350) | alignment | ||
Range on Protein: 739-847
Range on HMM: 51-158/350.0
NRFRDILPNPVTRVRLE-----PLEVDHTL---EYINANYVRDPSAPCDNKPALlgfggrrakEYVAAQAPKDTGLFNFWRMIVHVQARCIAMTTGLVEG
||...||| .||.|. . ..|.| .||||||.. . . .| |.|.||| . .|...|.. . . | . | .||
nrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdf.........kYiatqaPlpstvddfykvillnkvkvilsltsdvel
GKNKCSRYWPATIYAET
. .|| |||. | .
nlekcyrYWqegsyddi
|
|||||||||
| 0044763 | (Phosphotyrosine protein) phosphatases II | 748-996 | 1.4e-23 | 78.9 | In-house | 3-167 (178) | alignment | ||
Range on Protein: 748-996
Range on HMM: 3-167/178.0
PVTRVRLEPLEVDHTLEYINANYVRDPsapcdnkpallgfggrrakEYVAAQAPkdtglFNFWRMIVHVQARCIAMTTGLVEGGKNKCSRYWPATIYaet
. ||| |..|| . .||||... . |.... | ...... ..| . |. .|.|..|| .|||
drtrvllsnleglersdyinaseilpg...................lylgslpp.....addlellkelgithivnlteelelgflkcdpywpeeag...
keelvygprdgkihvrtmlvtkmegyiktniqvlyqgstrnlVHFWFTAWPDHGVPTRPDGSMQTQQMIEMLLdirrtrnelDRAESPLIVHCSAGIGRT
... .. .||||||. .. ... ..|| .| |. ..| .||||||.||.
..........................................iqylhipipDhgvpdllehflefvefieeal.........dekggpvlVHCsaGvgRs
GTMIALDHAMCAldmgvKVDVLSIVADIREDRMaMVQHVVQYRYLYQAV
||..|.. .. .... .... .|| |. .|.. |.|.||.
gtlvaaylmkkl.....glsleeaielvrerRp.ivpnpgqlrqLyefe
|
|||||||||
| 0046846 | (Phosphotyrosine protein) phosphatases II | 757-1001 | 2.4e-30 | 101.0 | In-house | 6-174 (176) | alignment | ||
Range on Protein: 757-1001
Range on HMM: 6-174/176.0
LEVDHTLEYINANYVRDPsapCdnkpallgfggrrakeYVAAQAPKDTGLFNFWRMIVHVQARCIAMTTGLVEGGKNKCSRYWPATIYAETkeelvygpr
| | | |||||.. . . ..| |.| | .|..|. . . ... . | .|| |. || .||| ..
lgldldldyinanlilgs...r................piatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpeleklgi.........
dgkihvrtmlvtkmegyiktniqvlyqgstrnlvHFWFTAWPDHGVPTRpdgsMQTQQMIEMLLDIRRTRneldraeSPLIVHCSAGIGRTGTMIALDHA
..... |||||||. . ....|.. . .. | .||||||||||||..|..
..................................qylhlpwpDhgvpdl....elllellefirealkeg.......gpvlVHCsaGigRtgtlvaayll
MCaldmGVKVDVLSIVADIREDRM-AMVQHVVQYRYLYQAVVEYAE
.. . ..|. ..| .|| |. .||. |||.||... .. .
el....ekglsveealalvreqRplgavqtpeQyrflyefellllk
|
|||||||||
| 0051082 | (Phosphotyrosine protein) phosphatases II | 764-996 | 1e-24 | 82.3 | In-house | 4-149 (151) | alignment | ||
Range on Protein: 764-996
Range on HMM: 4-149/151.0
EYINANYVRDPsapcdnkpallgfggrrakeYVAAQAPKDtglfNFWRMIVHVQARCIAMTTGLVEGGknKCSRYWPATIyaetkeelvygprdgkihvr
|||..|| . . . ..| . |.... . . ..| . ....| | .| .|.|..
dyinfsyvtgg....................lyrsggpla....dflellkelgiktivnlrseeerg..ycpeylpelg....................
tmlvtkmegyiktniqvlyqgstRNLVHFWFTAWPDHGVPTRPdgsMQTQQMIEMLLDirrtrneldRAESPLIVHCSAGIGRTGTMIALDHAMCAldmg
....|.... |||.|.|. . . ....|.||| . |..||||||.|||||..||. ..
.......................ievlhipildwpdpglplsf...davleflellld.........kkngpvlvHCsaGkgRTGtlvalylmllg....
vkVDVLSIVADIREDRMAMVQHVVQYRYLYQAV
|.. ......|. |. .||. |......|.
..vsleealeeyrlkrpgvvqpnqqflfqlfal
|
|||||||||
| subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 764-847 | 8e-07 | 22.7 | In-house | 91-161 (349) | alignment | ||
Range on Protein: 764-847
Range on HMM: 91-161/349.0
EYINANYVRDPSAPCDNkpallgfggrrakEYVAAQAPKDTGLFNFWRMIVHVQARCIAMTTGLVEGGKNKCSRYWPATIYAET
.||||||.. . .. |.| ||| . . .|...|. . . . . | . .|| .|| |..
dyinanylkltrisvek.............kyiatqaPlPstvddfykvillngvklvlsLnddkelslekcdiywqelsysni
|
|||||||||
| 0051429 | (Phosphotyrosine protein) phosphatases II | 765-1020 | 1.1e-40 | 135.3 | In-house | 6-244 (272) | alignment | ||
Range on Protein: 765-1020
Range on HMM: 6-244/272.0
YINANYVRDPsapcdnkpallgFGGRRAKEYVAAQAPKDTGLFNFWRMiVHVQARCIAMTTGLVEGGKNKCSRYWP--ATIYAETKEELVYGPRDGKIHV
||||..| . .. . . . ....| . .|||. . . ..| . ....| |..||.|||| .. . .. .. .. |...|
yiNardvggy............grvvkpgrlyrsggplpltaadfwrl.kelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrv
RTMLVTKMEGYIKTNIQVL---YQGSTRNLVHFWFTAWPDHGVPTRPdgsmqTQQMIEMLLDirrtrneldraESPLIVHCSAGIGRTGTMIALDHAMCA
... .. .. || ..... . | .| . |...|.|||||||. . ...|.||| . |..||||||..||||..||.. .
tllseellldyilrellltlllsagearevmhlhytdwpdhgvpqea.....llellellld...........ggpvlvHCsaGkdRTGtvvallllllg
LDMGVKVD--------VLSIVADIREDRMAMVQHVVQYRYLYQAVVEYAERLAAREQEeEAAQAYEQMR
... . || .. .|. .|. |...||. ||..||.|..|....|.... | ..|.....
vsletivddYlltnlyleeaveelraqrpgavqteeqylflyeallellrsllsvrae.yllaaldaid
|
|||||||||
| subfamily_Cele-PTP-10_pd | Subfamily Cele-PTP-10 | 769-999 | 1.1e-26 | 88.2 | In-house | 72-288 (305) | alignment | ||
Range on Protein: 769-999
Range on HMM: 72-288/305.0
NYVRDPSaPCDNKP-ALLGFGGRRAKEYVAAQAPKDTGLFNFWRMIVHVQARCIAMTTGLVEGGKNKCSRYWPATIyaETKEELVYGPRDGKIHVRTMLV
. .|| |.| .| | ...|| | | . .|| |... . | | || || ||..||||. | || | .. .
vkldkps.psdyihanyvgcpmipekrficaqgpldqtidefwwmviqnkveqivmlcktvelgklkcaqywpaaq..geklelksgivvenvsgskpme
TKMEGYIkTNIQVLYQG-STRNLVHFWFTAWPDHGVPTRPDGSmqtqqmIEMLLDIRRTRneldraeSPLIVHCSAGIGRTGTMIALDHAMCALDMGVKV
| | | ... | | . . |. .| ||| ||| | .|.| || .. |..||||||||||||..|... . . ..
rdaeiqi.tllnltysgdqkmsvrhlqwtewpdrgvppcklts......lellsairgsk.......vpivvhcsagigrtgtivaieyilekiaenkpc
D-VLSIVADIREDRMAMVQHVVQYRYLYQAVVEY
. .| .|..| .| ||| .... ...|
ppmpelvkalrdqrafsiqndvqylfihrvmlny
|
|||||||||
| subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 781-998 | 1e-30 | 101.7 | In-house | 34-237 (237) | alignment | ||
Range on Protein: 781-998
Range on HMM: 34-237/237.0
KPALLGFGGRrAKEYVAAQAPKDTGLFNFWRMIVHVQARCIAMTTGLVEGGKNKCSRYWPATIYAETKEELVY----GPRDGKIHVRTMLVTKMEgYIKt
| || | |.|.||| | .. .||.|. . | | |||.|| . || .||| | .. | ||..|..| .|
atylkgfdgt.pkkyiaaqgplesscddfwqmvwqekcsvivmltgliegnelkchkywpstdqpaaygvltvslkkkeefsdytvrslllskrl.tlk.
niqvlyqgSTRNLVHFWFTAWPDHGVPTRPDGSMQTQQMIemlldIRRTRNeLdRAESPLIVHCSAGIGRTGTMIALDHAMCALDMGVKVDVLSIVADIR
| . . ||.|||.||| . .. .. | | |.. . .| |.|||||.|||| .. .| . ||. | |
........evrlihqyqftswpdrgvpqqtaallrfrkni.....inrsph.v.sesgpwiihcsagvgrtgiflvidamlrqakekkvvdiynyvysie
EDRMAMVQHVVQYRYLYQAVVE
||| ..| || ...|...|
edrpyiiqtkdqyvfihqtile
|
|||||||||
| subfamily_Cele-PTP-6_pd | Subfamily Cele-PTP-6 | 790-1002 | 9.3e-34 | 111.8 | In-house | 79-279 (307) | alignment | ||
Range on Protein: 790-1002
Range on HMM: 79-279/307.0
RRAKEYVAAQAPKDTGLFNFWRMIVHVQARCIAMTTGLVEGGKNKCSRYWPAtiyaETKEELVYGPRDGKIHVRTMLVTKM---EGYIK-TNIQVLYQGS
. | ...|| |... ..|| |.. . .. | ..| .| || .|||. | ..||.| . | | . . |. | .|. |...| . .
ikpkkficaqgplentqysfwamaiqekvesvimlckvielakikceqywpl....eegqklvfgeapntisvanlgakklapdedlinvttlkvdwaqk
TRNLVHFWFTAWPDHGVPTRpdgSMQTqqmIEMLLDIRRTRNeldraesPLIVHCSAGIGRTGTMIALDHAMCALDMGVKV-DVLSIVADIREDRMAMVQ
.| . |. .. |||.||| . . |..| .| .| |..||||||.||.||..|. . . |. |. .| ..|..| .|
srtiqhlqwenwpdrgvpqi...nlta...inlleavrydtn.......pvvvhcsaGvGrsGtivaislvqdkmiaGinckdmkklveelrsqrhyaiq
HVVQYRYLYQAVVEYAER
.|| ||.. ..||
teaqylylhrvlleyfle
|
|||||||||
| 0043147 | (Phosphotyrosine protein) phosphatases II | 791-994 | 2.7e-28 | 94.3 | In-house | 18-155 (172) | alignment | ||
Range on Protein: 791-994
Range on HMM: 18-155/172.0
RAKEYVAAQAPKDTGLFNFWRMIVHVQARCIAMTTGLveggknkcsrywpatiyaetkeelvygprdgkihvrtmlvtkmegyiktniQVLYQGSTRNLV
....| |.| . | ||||. . . ..| . |.| ...... .|. .
ipdrfiatqgplrntladfwrmlkelgithivnltel...................................................lydpellerlgi
HFWFTAWPDHGVPtRPDGSMQTQQMIEMLLDIRRtrneldraESPLIVHCSAGIGRTGTMIALDHAMcaldmgVKVDVLSIVADIREDRMAMVQHVVQYR
..... ||||||| .. ... . |. || ... . | .||||||.|||||..|.. . ..... .|| .|| |. .||. |||
qylylpwpDhgvp.llellleflefidellalsp........ggpvlVHCsaGvgRtgtlvaaylml......lglsleeavalvrekRpgavqnpsqyr
YLYQ
.||.
flyy
|
|||||||||
| subfamily_egg_pd | Subfamily egg | 791-1000 | 3.7e-15 | 50.4 | In-house | 81-270 (307) | alignment | ||
Range on Protein: 791-1000
Range on HMM: 81-270/307.0
RAKEYVAAQAPKDTGLFNFWRMIVHVQARCIAMTTGLVEGgkNKCSRYWPATiyaeTKEELVYGPrdGKIHVRTMLVTKMEGYI--KTNIQVLYQGSTRN
|.. |||| .||||. . . | | | .| ..| ||| . .. ||. | | ... .. | . . |.....
llnefilaqaplkntvddfwrmvfqeevqyivmltsrkes..erceyywpka....esdslvtvp..GslrienlkvdskadplfrvtklklvGgddeer
LVHFWFTAWpdhgvptrpdgsmQTQQMIEMLLDI-RRTRNeldrAESPLIVHCSAGIGRTGTMIALDHAMCALDMG--VKVDVLSIVADIREDRMAMVQH
. | . . . . | . |. || . | .|.. |. ...|..|.. |.. | | .| || | .| | |.
flehwqgdv.............nnssdvysplrvlrklrn....lskpvvvqdilGvskaatlvaieiallsllrGpitkslvlravvflrlrrrlsves
VVQYRYLYQAVVEYA
|..| ..|. |. .
vllylfvyrlvlfff
|
|||||||||
| 0049260 | (Phosphotyrosine protein) phosphatases II | 792-994 | 5.9e-30 | 99.4 | In-house | 8-144 (152) | alignment | ||
Range on Protein: 792-994
Range on HMM: 8-144/152.0
AKEYVAAQAPKDTGLFNFWRMIVHVQARCIAMTTGLVEGGKNKCSRYWpatiyaetkeelvygprdgkihvrtmlvtkmegyiktniqvlyqgstrnlvH
.|..|.|.| . | .||||. . ....| | | |.| || || .|. .
pfefiatqgpgpntladfwrmlkelgittivmltellelgklkceqyi...................................................q
FWFTAWPDHGVPTRPDGSMQTQQMIEMLldirrtrneLDRAESPLIVHCSAGIGRTGTMIALDHAMcaldmgVKVDVLSIVADIREDRMAMVQHVVQYRY
. .. |||||||. .. .. ..|| | . . . | .||||||.|||||..|.. . .|... .|| .|| |. .|.. |.|.
ylhlpwpDhgvpdlsqlllflllfiekl.........aldkggpvlVHCsaGvgRtgtlvaaylml......lgvsleeavalvrekRpgavpnpgqlrf
LYQ
||.
lye
|
|||||||||
| subfamily_Cele-PTP-19_pd | Subfamily Cele-PTP-19 | 792-992 | 5.7e-20 | 66.2 | In-house | 89-273 (301) | alignment | ||
Range on Protein: 792-992
Range on HMM: 89-273/301.0
AKEYVAAQAPKDTGLFNFWRMIVHVQARCIAMTTGLVEGGKNKCSRYWPATIYaetkEELVYGPRDGKIHVRTMLVTKMegYIKTNIQVLY---QGSTRN
.. ..|.|.| . .|| |.|. . |.| . || ..||. | | .| |.| | . ||. . ... | .| ...| . .||
phrfiatqgPlkntsedfwamlvqydvekivmlgqkvekleekceeylpvkis....ekldigrfkikiknkelilnkk..iskrtlevedstgkfatrt
LVHFWFTAWPDHGVPtrpDGSMQTQQMIEMLldirrtrnelDRAESPLIVHCSAGIGRTGTMIALDHAMCALDMGVKVDVLSIVADIREDRMAMVQHVVQ
..|. .. |.|.||| . ... ...|.. ..| |..|||||||||. ..|. . ... .... ....||.| ||.. |
vthyqysewtdrgvP...kshaelfdlmelv..........kksekPivvhcsaGiGrsvafigteylareveadptieltealkhlrehrwngvqtnsq
YRYL
..
lywm
|
|||||||||
| 0036282 | (Phosphotyrosine protein) phosphatases II | 793-994 | 9e-31 | 102.3 | In-house | 17-164 (174) | alignment | ||
Range on Protein: 793-994
Range on HMM: 17-164/174.0
KEYVAAQAPKDtglfnFWRMIVHVQARCIAMTTGLVEGGKNKCSRYWPAtiyaetkeelvygprdgkihvrtmlvtkmegyiktniqvLYQGSTRNLVHF
....| |.| . ||.|. . . ... | . ..| |. || .||| |.. .|. ...
prliagqgpla.....fwemlkelgittvvmlleekelglykcinywpe.......................................lredlerlgiqy
WFTAWPDHGVPTRPDgsmqTQQMIEMLLDIRRTrneldRAESPLIVHCSAGIGRTGTMIALDHAMCALDmGVKVDVLSIVADIREDRMAMVQHVVQYRYL
... |||||||. . ..... . ... . |..||||||.|||||..|.. .. | ||.|..|. .| |. |||. |||.|
lylpwpDhgvpdlsi....llefvkfveealse.....dpggpvlVHCsaGvgRtGtlvaaylmlrgll.eslvdaldlvrelRlqrpgmvqtpsQyrfl
YQ
|.
yy
|
|||||||||
| subfamily_Cele-PTP-11_pd | Subfamily Cele-PTP-11 | 793-1007 | 2.7e-24 | 80.4 | In-house | 82-285 (312) | alignment | ||
Range on Protein: 793-1007
Range on HMM: 82-285/312.0
KEYVAAQAPKDTGLFNFWRMIVHVQARCIAMTTGLVEGGKNKCSRYWPATI-YAETKEELVYGPRDGKIHVRTMLVTKMEGYIkTNIQVLYQGSTRNLVH
. .|..|.| . .||.. . . . .| . .|.|| | .||..| . . . .. || .| . |. . .. | | .| |
erfvctqgplentcthfwqlalslgstsiillcgfvedgsekcakyisdivgfvdledhrvyteycteieiggkskdkithrv.lkvvvkatgqesklnh
FWFTAWPDHGVPTRPDGSMQtqqmieMLLDIRrtrneldRAESPLIVHCSAGIGRTGTMIALDHAMCALDMGVKVDVLSIVADIREDRMAMVQHVVQYRY
. ...|||||.| | ... .| .. . |.| |||||.|||||.. .. ..|| | .| . .| || |. . || |
yqwaswpdhgmpdscdtalr......llsavk.......kdkkpviahcsagvgrtgtlaliesmiaalrhprkqnvkdsfvllrkdrarsvrvfpqyvy
LYQAVVEYAERL--AARE
..|.|. |.
alrcvleflyskglykrn
|
|||||||||
| subfamily_Anemone-PTP-3_pd | Subfamily Anemone-PTP-3 | 793-994 | 9.7e-15 | 49.3 | In-house | 5-198 (199) | alignment | ||
Range on Protein: 793-994
Range on HMM: 5-198/199.0
KEYVAAQAPKDTGLFNFWRMIVHVQARCIAMTTGLVEGGKNKCSRYWPATIYAETKeelvYgprdGKIHVRTMLVTKMEGYIKTNIQ----VLYQGSTRN
. |.|.| | . .||.|. . | | . . |||.| . .| | | . | | .| | | . . |||.
rryiatqhplretmadfwqmvwetgsghivmvnddqknkeadypfywpttesgtgk....y....gslsvttktittkpdytitaliltnnttappstre
LVHFWFTAWPDHgvpTRPDGSMqtqqMIEMLLDIRRTRNELD-RAESPLIVHCSAGIGRTGTMIALDHAMCALDM--GVKVDVLSIVADIREDRMAMVQH
. |. ||.| .. | |. .. .. ... | . . ..|.||||| | | || ..||| . . . ||.. . .|. | ..
ishyqftswkek...ttpnval....fvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiiss
VVQYRYLYQ
. .| ..||
lqhynfiyq
|
|||||||||
| subfamily_Nvec-PTP-3_pd | Subfamily Nvec-PTP-3 | 793-994 | 1.1e-14 | 49.1 | In-house | 4-197 (198) | alignment | ||
Range on Protein: 793-994
Range on HMM: 4-197/198.0
KEYVAAQAPKDTGLFNFWRMIVHVQARCIAMTTGLVEGGKNKCSRYWPATIYAETKeelvYgprdGKIHVRTMLVTKMEGYIKTNIQ----VLYQGSTRN
. |.|.| | | .||.|. . | | . . |||.| . .| | | . | | .| | | . . |||.
rryiatqhplretladfwqmvwetgsghivmvnddqknkeadypfywpttesgtgk....y....gslsvttktittkpdytitaliltnnttappstre
LVHFWFTAWPDHgvpTRPDGSMqtqqMIEMLLDIRRTRNELD-RAESPLIVHCSAGIGRTGTMIALDHAMCALDM--GVKVDVLSIVADIREDRMAMVQH
. |. ||.| .. | |. .. .. ... | . . ..|.||||| | | || ..||| . . . ||.. . .|. | ..
ishyqftswkek...ttpnval....fvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiiss
VVQYRYLYQ
. .| ..||
lqhynfiyq
|
|||||||||
| subfamily_eak_pd | Subfamily eak | 793-1009 | 9.3e-11 | 35.7 | In-house | 93-314 (332) | alignment | ||
Range on Protein: 793-1009
Range on HMM: 93-314/332.0
KEYVAAQAPKDTGLFNFWRMIVHVQARCIAMTTGLVEGGKNKCSRYWPAtiyaETKEELVYGPRDgkIHVRTMlvTKMEGYIKTNIQVLYQGSTRNLVHF
..|. . ..... .| ||.|.. .. .| . || . .| .|.| .|.||| .| | .. . | . . .... | .. |.
rkyiltGiasedkvfafwqmvleqkspaivqlledvelkleksdkyfpd....ktreelkfGild..verkef..vkrniletrllelskGnethrvlhy
WFTAWPDHGVPTRPDGSMQTQQMIEM-LLDIRRTRNE-----------LDRAESPlIVHCSAGIGRTGTMIALDHAMCALDMGVK--VDVLSIVADIRED
. | . .| | . | |. | . .... . .| |. .. | |.|... .| . .| .| | .. ...
kvfGwtettlpkyedflalrkvmkevGvlllivmksallsstlkkyihtppsfap.iiqsarGsaraGvfvvidllirlidnkkknlysvedlilkvksk
RMAMVQHVVQYRYLYQAVVEYAERLAAREQE
|. | |. ..|..|..| | | ..
rihsvlvalqhsfiyeivldyllrrnnrlrd
|
|||||||||
| subfamily_Cele-PTP-16_pd | Subfamily Cele-PTP-16 | 793-999 | 4.1e-08 | 27.2 | In-house | 83-278 (303) | alignment | ||
Range on Protein: 793-999
Range on HMM: 83-278/303.0
KEYVAAQAPKDTGLFNFWRMIVHVQARCIAMTtgLVEGGKNKcsrYWPATIYAETKEELVYGPRDgkIHVRT-MLVTKMEGYIKTNIQVlYQGSTRNLVH
| . .| | .||.||.. . .|. . | .. .| . ... . .. | . | | | | ..|. . | .|. . ..|
kkailtqlplshtaadfwqmiieqkvkcvlll..ltdseydk...lggdsvfprnqdflkfeers..irvgefkrvelgdgwvlkvlsv.sngdyksflh
F-WFTAWPDHGVPTrpDGSMQTQQMIEMLLDIRRTRNEldraESPLIVHCSAGIGRTGTMIALDHAMCALDM-GVKVDVLSIVADIREDRMAMVQHVVQY
. ||| .|. ||| . . | | . | . .| . .| ||.||. .. | .| .|.. . .|. |. || . |.
vhhykawphnsips..dgspkfvkqiwqlqsvlrkysd....stptvymslsgcgragtfalfetahlslhseqasldlvkclenvrngrlhavqnlsqf
RYLYQAVVEY
..| . |.
svvytllaeh
|
|||||||||
| subfamily_Cele-PTP-1_pd | Subfamily Cele-PTP-1 | 794-1015 | 6.8e-10 | 33.6 | In-house | 72-277 (290) | alignment | ||
Range on Protein: 794-1015
Range on HMM: 72-277/290.0
EyvaaQAPKDTGLFNFWRMIVHVQARCIAMTTGLVEGGKN----KCSRYWPATIYAETKeelvYGprdgKIHVRTMLVTKMEGYIKTNIQVLYQGSTR-N
.. ...|| |. ... . |. | .| |..| | .. | | .. . |. | .. .. .. | ...
i....tekrnStiekfwwmakqEkvkqvVmlcefeeksantslfaCakYvpesvgeelk....fk....gltvkCkskekeddvetRelvvkfddeeeft
LVHFWFTAWPDHGVPTrpdgsmQTQQMIEMLldirrtrNELDRAESPLIVHCSAGIGRTGTMIALDHAMCALD-MGVKVDVLSIVADIREDRMAMVQHVV
. | .. | . |. .|. ..... . . ..| |||| || | .. |.. .. . . .| . ... ..|. | ....
vtHsllkgWnklnvqe......dtktllsli.......qkvkasktpvivHcvdGiSrsAalaaiilgyQkiaetsgsvkledvlkalrkqralaitsal
QYRYLYQAVVEYAERLAAREQEEEAA---QA
.. . ..| .| . . ||| .|
elafvdagivllaievldqfaeeetekkaka
|
|||||||||
| subfamily_Cele-PTP-7_pd | Subfamily Cele-PTP-7 | 798-995 | 1.9e-16 | 54.4 | In-house | 96-283 (302) | alignment | ||
Range on Protein: 798-995
Range on HMM: 96-283/302.0
AQAPKDTGLFNFWRMIVHVQARCIAMTTGLVEGGKNKCSRYWPATIyaetKEELVYG---PRDGKIHVRTMLVTKMEGYIKTNIQVLYQ----GSTRNLV
|| | .| .| . . .. ...||....||. |. . ..|| .| . ... | ... .... . . .
pivpkkstlekhwalieqynvaivvqlcsfvedeekkcaeyysdkv....ggelkfgrytvktvsvktdleeftdkksfklytveiknekkkkkvkktvd
HFWFTAWPDHGVPTRPDGSMQTQQMIEMLldirrtrneldraESPLIVHCSAGIGRTGTMIALDHAMCALDMGVKVDVLSIVADIREDRMAMVQHVVQYR
. |.|||||| | .. ... . | ..||||||.|||||..|. . . |.|||| .|. | ||. |
ilafsawpdhGapkeaytaldilkfcesy.............kknvlvhcsaGvGrtGtlvaikyGiqlcskkkvtdllsivlpvrqcryGavqdeqqli
YLYQA
||
ylllc
|
|||||||||
| subfamily_Cele-PTP-4_pd | Subfamily Cele-PTP-4 | 798-1008 | 3.2e-14 | 47.1 | In-house | 95-293 (302) | alignment | ||
Range on Protein: 798-1008
Range on HMM: 95-293/302.0
AQAPKDTG---LFNFWRMIVHVQARCIAMTTGLVEGGKnKCSRYWPATiyaetKEELVYGprdGKIHVRTMLVTKMEGYI-KTNIQVLYQGSTRNLVH--
|| || . . .||||. . . . . | | | | ..| . .. .. ||. | . | |.|. . | || .| . ..
aQlpkvdsedsveeFWrmvfqekivsvvilvgeeelkk.tlselfpkk.....sgdykey...gkmfvNnrkVekaeeektryviEvlPegcsnsvlanv
FWFTAWPDHGVPTRPDGSMQTQQMIemlldirrTRNELdRAESPLIVHCSAGIGRTGTMIALDHAMCALDMGVKVDVLSIVADIREDRMAMVQHVVQYRY
.| |... ||.. ..| . . .. |...... |.|| |....| |.. |. | .. . ||. ||..| ..|. . ||
yvltnWkqkkvpvkyaeliktaakv........fakki.kadentvivSknGaGRagafltlavaveklqkgkepnikeivksiRsqRpravdslkQyvs
LYQAVVEYAERLAAREQ
|| |.. | . ...
lyialllyikkkvtkpe
|
|||||||||
| subfamily_Cele-PTP-9_pd | Subfamily Cele-PTP-9 | 807-1007 | 8.9e-13 | 42.9 | In-house | 42-226 (255) | alignment | ||
Range on Protein: 807-1007
Range on HMM: 42-226/255.0
FNFWRMIVHVQARCIAMTTGLVEGGKNKCSRYWPAtiyaETKEELVYgpRdgKIHVRTMLvTKMEGYIKTNIQVLYQG---STRNLVHFWFTAWPDHGVP
.|...|| .. ..| . . | |..|||.|.| | | |.. .. | | . . ..| ... | |... |. .. |... |
dkfyqtivqtktevvvmlcdfaeegvekcssyfpl....ekdeklkl..a..dvnvtttk.ssadvvlrtleitstlgekkkthtvkhysykGWieknaP
TRPDgsmqtqqMIEMLLdiRRTRNEldraeSPLIVHCSAGIGRTGTMIALDHA----MCALDM--GVKVDVLSIVADIREDRMAMVQHVVQYRYLYQAVV
. | .| . |. ...||||.||||. ... . . . .|| |..| ||.. ..|. | . .. .| . |.
elar.......eilnil..kvvrds.....ksvvvhCstGiGrsaafvlaelvyqkmirsldttetveldylslleelrskrkraihtPlqlafsilmvl
EYAerLAARE
.. . |
dlv..fpkge
|
|||||||||
| subfamily_hpo-7_pd | Subfamily hpo-7 | 808-1020 | 2.4e-10 | 34.7 | In-house | 49-244 (263) | alignment | ||
Range on Protein: 808-1020
Range on HMM: 49-244/263.0
NFWRMIVHVQARCIAMTTGLVEGGKNKCSRYWPAtiyaETKEELVYgprdGKIHVRTMLVTKmEGYIKTNIQVLYQG---STRNLVHFWFTAWPDHGVPT
.|...|| .. ..| . | |..|||.|.| | | ... .. | | | . . .||. . . | |... |. .. |... |.
kfyqtivqtktevvvmLcDfneegvekcssyfPl....ekdekqkl....anvnvcttkvqs.dvllktlellstlgeKkkthtvkhysykgWiekndpe
RPdgsmqtqQMIEMLLDIRRTRneldraeSPLIVHCSAGIGRTGTMIALDHA----MCALDM--GVKVDVLSIVADIREDRMAMVQHVVQYRYLYQAVVE
. . | .|.. | .|.||||.||||. . . . .|| |..| ||.. ..|. | . .. .| . |..
la.......reilnilkvarns.......kslvvhcstGiGrsaafsvaElvyqkmirsldttstveldylsLleelrssrkraihtPmqLafsilmvLd
YAERLAAReqeEEAAQAYEQMR
. |. .|. |...|
fvlnnfak...geleakyqeir
|
|||||||||
| 0048076 | (Phosphotyrosine protein) phosphatases II | 877-998 | 2.1e-21 | 71.5 | In-house | 35-141 (145) | alignment | ||
Range on Protein: 877-998
Range on HMM: 35-141/145.0
NIQVLYQGSTRNLVHFWFTAWPDHGVPTRPDGSMQTQQMIemlldirrtrNELDRAESPLIVHCSAGIGRTGTMIALDHAMCaldmgVKVDVLSIVADIR
|. .. .|. ...... |||||||. .. .. ..| .|. ... | .||||||.|||||..|.. .. .|.. .... .|
nltselellerlgiqylylpwpDhgvpdllellleflefi..........eealkeggpvlVHCsaGvgRtgtlvaaylmll.....lgvsleealelvr
EDRMAMVQHVVQYRYLYQAVVE
. |. .|... |.|.||... |
sqrpgavpnpgqlrflyefele
|
|||||||||
| 0048179 | (Phosphotyrosine protein) phosphatases II | 881-994 | 1.2e-19 | 65.9 | In-house | 41-139 (144) | alignment | ||
Range on Protein: 881-994
Range on HMM: 41-139/144.0
LYQGSTRNLVHFWFTAWPDHGVPTRPDGSMQTQQMIEMLldirrtrnelDRAESPLIVHCSAGIGRTGTMIALDHAMcaldmGVKVDVLSIVADIREDRM
.. .|. ...... |||||||. .. .. ..|| . . . | .||||||.|||||..|.. . .... ...| .|. |.
epefleregiqylhlpwpDhgvpdllellleflefieea..........leeggpvlVHCsaGvgRtgtlvaaylmk.....klglsleealalvrsrrp
AMVQHVVQYRYLYQ
.|.. |.|.|..
gavpnpgqlrfLle
|
|||||||||
| subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 881-1020 | 4.6e-17 | 56.5 | In-house | 83-214 (440) | alignment | ||
Range on Protein: 881-1020
Range on HMM: 83-214/440.0
LYQGSTRNLVHFWFTAWPDHGVPTRpdgsmqTQQMIEMLLDIRRTRNEldRAESPLIVHCSAGIGRTGTMIALDHAMCALDMGVKVDVLSIVADIREDRM
. .| | .. . .|||.||| . ...|. |. .... ...||.|||||| |||| .||.| . ..|..|.. .|..|
ingiesrtlkqyhyqgwpdkgvpkf......agpvlkmiqdvnesqek..agngpllvhcsagagrtgviiavdsilreakrsdqidifsfinsmrnnrp
AMVQHVVQYRYLYQAVVEYAERLAAREQEEEAAQAYEQMR
||| || ....||.| . |.. .. ||..
qmvqtpeqyafvheavlegllcgdtliledditerveqiq
|
|||||||||
| subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 888-1000 | 4.7e-14 | 46.5 | In-house | 219-344 (349) | alignment | ||
Range on Protein: 888-1000
Range on HMM: 219-344/349.0
NLVHFWFTAWPDHGVPTRPDGSMQTQQMIEMLLDIRRTRNELDRAES-PLIVHCSAGIGRTGTMIALDHAMCALDM----GVKVDVLSI--------VAD
|. . . |.| .. | .|. .. . |.| .|. || ... .|.|||||| ||||... || . | . .|... .. |
ellqlqvknwldlslllnPisilqalevkndliddlfarlyldtdqlstllvhcsaGcGrtGvlvtldlllsileplqnesnkiklqallkDlisiivne
IREDRMAMVQHVVQYRYLYQAVVEYA
.| |..||| . |. .|.|...|
lrkqrismvqnlaqfiaiyealLkyf
|
|||||||||
| subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 889-1000 | 3.1e-18 | 60.6 | In-house | 217-344 (350) | alignment | ||
Range on Protein: 889-1000
Range on HMM: 217-344/350.0
LVHFWFTAWPDHGVPTRPDGSMQTQQMIEMLLDIRRTRNELDRAE-SPLIVHCSAGIGRTGTMIALDHAMC---ALDM----GVKVDV--------LSIV
. .. . |.| .. .| .|. .. . |.| ... || |. ||..||||||.|||||...||. . |.. .|.|| ||
vyqlqvknWkDlslllnPesilqalevkndliddlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaaktrDlisiiv
ADIREDRMAMVQHVVQYRYLYQAVVEYA
.|. |. ||| . |. ..|.|. |
nelrkqrismvqnldqfifiYeallfyf
|
|||||||||
| PTPc_DSPc_SM00012 | 890-997 | 2.5e-29 | 96.9 | In-house | 3-104 (105) | alignment | |||
Range on Protein: 890-997
Range on HMM: 3-104/105.0
VHFWFTAWPDHGVPTRPdgsmqtQQMIEMLLDIRRTRNELDRaESPLIVHCSAGIGRTGTMIALDHAMCALDMG-VKVDVLSIVADIREDRMAMVQHVVQ
|...|.|||||||... . ..|.| .... .|. .. ..|..||||||.|||||..||| ... |. . .||.. || .|. |. ||| |
khyhytgwpdhgvPees......dsilellravkknknkses.skpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgmvqteeq
YRYLYQAVV
| .||.|.
ylflyrall
|
|||||||||
| 0038934 | (Phosphotyrosine protein) phosphatases II | 896-998 | 1.4e-07 | 26.9 | In-house | 86-175 (194) | alignment | ||
Range on Protein: 896-998
Range on HMM: 86-175/194.0
AWPDHGVPTRPDGSMQTQQMIEMLLdirrtrnElDRAESPLIVHCSAGIGRTGTMIAldhamCALDMGVKVDVLSIVADIREDRMAMVQHVVQYRYLYQA
.||.|.. . .. .... | . . .. ||| ||.|||||..| ..| . . .. .| .|| | ..... ....|..
pfpddgtvPsleillrfldlvdefl.......n.edpggvvaVHCkaGlgRtGtlva.....aYLiyrlgmsaeeAialfrekRpgaipnqdyleallkr
VVE
. |
yke
|
|||||||||
| subfamily_CDC14_pd | Subfamily CDC14 | 907-953 | 7.9e-06 | 19.9 | In-house | 243-283 (328) | alignment | ||
Range on Protein: 907-953
Range on HMM: 243-283/328.0
DGSMQTQQMIEMLLDIrrtrneLDRAESPLIVHCSAGIGRTGTMIAL
|||. ...... .|.| ...|| ..||| ||.|||||.||
DGstPsdaivkkflei......aekaeGaiavhCkaGLGrtGtLiac
|
|||||||||
| subfamily_CG42327_pd | Subfamily CG42327 | 932-1003 | 5.5e-17 | 56.4 | In-house | 246-318 (319) | alignment | ||
Range on Protein: 932-1003
Range on HMM: 246-318/319.0
AESPLIVHCSAGIGRTGTMIALDHAMCALDMG-VKVDVLSIVADIREDRMAMVQHVVQYRYLYQAVVEYAERL
||.|||| |.||||..|| | |. |. ||. .| .|.|| |. . || ..|. . |||. |
sqGPlvvhcsdGvGrtGlviasdiairsleeskrsvdiPqlvssvrrdrasavltkeqyefiykvlseyakkl
|
|||||||||
| subfamily_PTEN_pd | Subfamily PTEN | 936-993 | 5.4e-06 | 21.5 | In-house | 117-173 (184) | alignment | ||
Range on Protein: 936-993
Range on HMM: 117-173/184.0
LIVHCSAGIGRTGTMIALdHAMCALDMGVKVDVLSIVADIREDRMAMVQHVVQYRYLY
.||| || ||||..|. . . .| . . ..|.. | .| |. | ||..
vvvHCkaGkGRtGvliva.yllkslllekaeealelfaeaRtknkkgvtiPsqrRYve
|
|||||||||
| subfamily_Sponge-PTP-7_pd | Subfamily Sponge-PTP-7 | 937-998 | 2.5e-09 | 31.4 | In-house | 2-63 (69) | alignment | ||
Range on Protein: 937-998
Range on HMM: 2-63/69.0
IVHCSAGIGRTGTMIALDHAMCALDMGVKVDVLSIVADIREDRMAMVQHVVQYRYLYQAVVE
.||||.| |||||.||. | . ||.. | .| | || ..| ... |.||
vvhcssgtgrtgtfiaimvemarikseklvdifnnvqymrkcrpmmvmneieyifihdalve
|
|||||||||
| subfamily_Sponge-PTP7_pd | Subfamily Sponge-PTP7 | 937-998 | 1e-08 | 29.4 | In-house | 1-62 (69) | alignment | ||
Range on Protein: 937-998
Range on HMM: 1-62/69.0
IVHCSAGIGRTGTMIALDHAMCALDMGVKVDVLSIVADIREDRMAMVQHVVQYRYLYQAVVE
.||||.| |||||.||. | . ||.. | .| | || .| ....|.||
vvhcssGtGrtGtfiaimvemarikseklvdifnnvqymrkcrpmmvmneneymfihdalve
|
|||||||||
| SH2 | SH2 domain | 1116-1197 | 7.4e-13 | 39.0 | Pfam-A | 1-77 (77) | alignment | ||
Range on Protein: 1116-1197
Range on HMM: 1-77/77.0
WFRSNFTRAQVEDLLSG-TPPGTFVVRPSS-KKDHFALSLQTVRhkiaNMLIVPIAQPN-GkflyKLGASNDQSFSSVAELVEHY
|. . .|...|.|| ..|||.||.|. |.....||. . . .. . | . . | |. .....|||..||||||
WyhgkisreeaerlLlegkkdGtFLvReSeskpGdytlsvvddg....kvkhyriqsleng....kyyitenekfsslqeLvehY
|
|||||||||