Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
| Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
|---|---|---|---|---|---|---|---|---|---|
| subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 482-736 | 1.3e-29 | 97.9 | In-house | 17-274 (287) | alignment | ||
Range on Protein: 482-736
Range on HMM: 17-274/287.0
EAVQTASaSVLTYQYQTAMLPHNLEKNvRRNTLLPYEYNRVLLANPGEKD-QYYNASFIPTYSPQMPIIVAEGPQRPTLTLFWQMMWQQEVSLVAMTTTI
.|.. | |. ...| . .|| | .||.. .||||.. ||. .| || ....| . |.| || |. ||......... |.. |
dalkeds.esstatfkaaeelaavkkn.ryadvlPiddtrvllsaegelGsdyinanyvasytddeafiaaqgPiaatvrdfwravletrsasvitmtre
SDGSQVVGERYWPSEGDILEIGPLQIT-LEHEHTNLAICERSLRVKHIDLGITRDVKLLQMLFWVAGEACEDSHRFLAFAERV---RDARSKLKPDQPLL
. .. .||| . .| .. |... . . |.||. ... .| || |..| | .. . . .. |. | ... . . ||.
veearlkcykywPerevPmrvGGysvvlldydikePeygvralrlidletrearvvkqldllswPdkvlaPtavglirfvldvkqhielardasevGPlv
VHGITAVGRAGAFCALLNLLDRFDNERRLNVVDELTRLRQARSHFISDVVYLETILACVL
|| . .||.| . |.| |..| . |..| . |||. | .. || | . .
vhddvGiGrsGillatlvlvsrledlGrvdvaavvirlreyraalvqavvqlrllyealv
|
|||||||||
| subfamily_Cele-PTP-12_pd | Subfamily Cele-PTP-12 | 485-581 | 2.4e-07 | 24.6 | In-house | 15-111 (332) | alignment | ||
Range on Protein: 485-581
Range on HMM: 15-111/332.0
QTASASVLTYQYQTAMLPHNLEKNvRRNTLLPYEYNRVLLANPGEKDQYYNASFIPTYSPQMPIIVAEGPQR-PTLTLFWQMMWQQEVSLVAMTTTIS
. .| .|| . |.. | | | ....|| || ||..||||.. || . |.|. | | .||.|. ... |.. . |
nqmhtsamtypntydkflnnmdmn.riphlycfdhsrvelapqdgkddfynaswvdgyskksayifaqapfndhteyvfwrmvserkpsmilvfgdid
|
|||||||||
| subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 486-725 | 1.8e-38 | 127.5 | In-house | 38-276 (298) | alignment | ||
Range on Protein: 486-725
Range on HMM: 38-276/298.0
TASASVLTYQYQTAMLPHNLEKNvRRNTLLPYEYNRVLLAN--PGEKDQYYNASFIPTYSPQMPIIVAEGPQRPTLTLFWQMMWQQEVSLVAMTTTISDG
. | .. . ... | |.| .|| | ...... ||.| . |. .| ||||. .|. . . |....| .|.. ||.|....... . | |.. .
svsseieeeekevarkpenkkkN.RyadiialdssRvvLekedadeesdYiNAsflhaykgrnafiatqaPltetvedFWrmvteedigtiVmltnleel
SQVVGERYWPSEGDiLEIGPLQITLEHEHTNLAICERSLRVKHIDLGITRDVKLLQMLFWVAGEACEDSHRFLAFAERVRDaRSKLKPDQPLLVHGITAV
.. ..|||.|| . | ....| .... . | | |.. . .| |. |.. | . | .. |.. ..|| . ..|..|. |
dktkyhkywPdegk.etygeitvsllskeefadlivrklkvskkkeekerevrqlhftsWpdkgvpenatsvldllrkvra.sqqqagnkpvivqCsaGv
GRAGAFCALLNLLDRFDNERRLNVVDELTRLRQARSHFISDV
||.|.|.|. .|.| .|. . | . . .||. | . .
gRsGtfiaidsvlervkkeqvvDvfqvvkvlRkkrpgavqte
|
|||||||||
| DSPc_SM00195 | 490-739 | 9e-44 | 145.1 | In-house | 12-262 (263) | alignment | |||
Range on Protein: 490-739
Range on HMM: 12-262/263.0
SVLTYQYQTAMLPHNLEKNvRRNTLLPYEYNRVLLANPG--EKDQYYNASFIPTYSPQMPIIVAEGPQRPTLTLFWQMMWQQEVSLVAMTTTISDGSQVV
| . . ..| ..| .|| | . |||. .|| | .. |...|.||..| ..... .|.. ||. |. ||.|.|...|....|.| .. .
stspketteaekkknkskn.RyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivmlteeeengkek
GERYWPSE-GDILEIGPLQITLEHEHTNL-AICERSLRVKHIDLGITRDVKLLQMLFWVAGEACEDSHRFLAFAERVRDARSKLkpDQPLLVHGITAVGR
.||||.| |. ..| ....| .... | | |.... . ||.|. .|. | .. .. . .|.. . |. .|. ..|..|| . |||
cdrywpeesggketfgkisvklvevekkkdeiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkksksts..sgpivVhCsaGvgR
AGAFCALLNLLDRFDNERRLNVVDELTRLRQARSHFISDVVYLETILACVLDYA
.|.|... .|.....| .... . ...||. | . .. . .| ..|.|.
tgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaileyi
|
|||||||||
| PTPc_SM00194 | 490-739 | 9e-44 | 145.1 | In-house | 12-262 (263) | alignment | |||
Range on Protein: 490-739
Range on HMM: 12-262/263.0
SVLTYQYQTAMLPHNLEKNvRRNTLLPYEYNRVLLANPG--EKDQYYNASFIPTYSPQMPIIVAEGPQRPTLTLFWQMMWQQEVSLVAMTTTISDGSQVV
| . . ..| ..| .|| | . |||. .|| | .. |...|.||..| ..... .|.. ||. |. ||.|.|...|....|.| .. .
stspketteaekkknkskn.RyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivmlteeeengkek
GERYWPSE-GDILEIGPLQITLEHEHTNL-AICERSLRVKHIDLGITRDVKLLQMLFWVAGEACEDSHRFLAFAERVRDARSKLkpDQPLLVHGITAVGR
.||||.| |. ..| ....| .... | | |.... . ||.|. .|. | .. .. . .|.. . |. .|. ..|..|| . |||
cdrywpeesggketfgkisvklvevekkkdeiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkksksts..sgpivVhCsaGvgR
AGAFCALLNLLDRFDNERRLNVVDELTRLRQARSHFISDVVYLETILACVLDYA
.|.|... .|.....| .... . ...||. | . .. . .| ..|.|.
tgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaileyi
|
|||||||||
| subfamily_PTPN6_pd | Subfamily PTPN6 | 490-740 | 1.9e-29 | 97.7 | In-house | 40-298 (306) | alignment | ||
Range on Protein: 490-740
Range on HMM: 40-298/306.0
SVLTYQYQTAMLPHNLEKNVRRNtLLPYEYNRVLLANPGEKD-QYYNASFIPTY--SPQMPIIVAEGPQRPTLTLFWQMMWQQEVSLVAMTTTISDGSQV
. ... . . |.| ||| .| ||.. .|| |..|. .. .| ||..| . . . | ..| . |.. ||.|.||.. .. |||. . ..
akkllsrkegakpenkeknrykn.ilPfDhtrvilkepsvpgsdyinanyikkevkgsdksyiatqgclettvsdFWrmvwqensrvivmttkevErgke
VGERYWPSEGDILEIGPLQITLEHEHTNLAICERSLRVKHI-DLGITRDVKLLQMLFWVAGEACEDSHRFLAFAERVRDARSKLK--PDQPLLVHGITAV
||||.| . | | ...| .|... . |.|.|... . . .|.| .. | .| .|.| | |. ...|. |..|| .
kCarYWPdeeekeeyGkisvtnvseksladYilRelsvskkkkkkeerevfqyhfksWPdhgvpkdpgavLdfledvnrkqeeleeaeagpivvhCsaGi
GRAGAFCA---LLNLLDRFDNERRLNVVDELTRLRQARSHFISDVVYLETILACVLDYAA
|| |.| ||.|. . .. ... . .|. || .. . . |
GRtGtfiviDillkliekkgldadidiqklvksvreqrsglvqteqqykfvykaikkyie
|
|||||||||
| 0050432 | (Phosphotyrosine protein) phosphatases II | 492-743 | 1.3e-53 | 177.7 | In-house | 56-303 (308) | alignment | ||
Range on Protein: 492-743
Range on HMM: 56-303/308.0
LTYQYQTAMLPHNLEKNVRRNtLLPYEYNRVLLanpGEKDQYYNASFIPTY--SPQMPIIVAEGPQRPTLTLFWQMMWQQEVSLVAMTTTISDGSQVVGE
..| .|.|| | .|| .. |||...|| | .|.. |.|||....| .. .|.. || |. ||.|.|.|.|... | |.. . ... .
plleysvallpenkdkNrykd.ilpydhsRVkl...degsdYInAsyvdgyssklprkfIatqgPlpntvedFwrmvweqnvrvIvmLtklvengrekca
RYWPSE--GDILEIGPLQITLEHEHTNLAICERSLRVKHIDLGITRDVKLLQMLFWVAGEACEDSHRFLAFAERVRDARsklkPDQPLLVHGITAVGRAG
.|||.| |..||.|....|| .|... .. | |...... | .| |. .... | . .... .|.| |.||. . |. | .|| |||.|
qYwplelgggsleygkftvtllseevlddytvrtleltnlgdgesrtvthfhytnWpdhgvPpspeilldflelvrksl....pggpivVHCsaGvGRtG
AFCALLNLLDRFDNERRLNVVDELTRLRQARSHFISDVVYLETILACVLDYAANKD
.|.||. ||.... |....| . . .||. | . . .. ... . ..|.|. .|
tfialdllleqlekeggvdvfeavkklReqRpgmvqtpeqylflyralleylklkl
|
|||||||||
| 0046845 | (Phosphotyrosine protein) phosphatases II | 492-743 | 1.1e-52 | 174.5 | In-house | 16-278 (284) | alignment | ||
Range on Protein: 492-743
Range on HMM: 16-278/284.0
LTYQYQTAMLPHNLEKNVRRNtLLPYEYNRVLLANPGEK---DQYYNASFIPTY-----SPQMPIIVAEGPQRPTLTLFWQMMWQQEVSLVAMTTTISDG
|.... .|.||.||.|| .. .|||...|| | ..... . |.|||....| .. .|.. || |. ||.|.|.|.|... | |.. .
lllslsvallpenlsknRykd.ilpydhsRVklksldgdledsdYinAsyvdgydldltyikkkfIatqgPlpntvedFwrmvweqnvrvIVmltelven
SQVVGERYWPSEGDILEIGPLQITLEHEHTNLAICERSLRVKHID-LGITRDVKLLQMLFWVAGEACEDSHRFLAFAERVRDARSKLKPDQPLLVHGITA
... ..|||.||. |..|....|| .|... .. | |...... | .| |. .... | ..... .|.| . ||.....|... | .||
grekcaqYwplegevltygdftvtllseevkddytvrtleltnlgytgesrtvthfhytswpdhgvppspedlleflrlvrellenlpgggpivVHCsaG
VGRAGAFCALLNLLDRFDNER---RLNVVDELTRLRQARSHFISDVVYLETILACVLDYAANKD
|||.|.|.|| ||.....|. ...| . . |||. | ... . .. . ..|.|. .|
vgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvqtleqyrfvyealleylklkl
|
|||||||||
| 0036941 | (Phosphotyrosine protein) phosphatases II | 492-743 | 5.3e-52 | 172.3 | In-house | 27-281 (297) | alignment | ||
Range on Protein: 492-743
Range on HMM: 27-281/297.0
LTYQYQTAMLPHNLEKNVRRNtLLPYEYNRVLLanPGEKDQYYNASFIPTYSPQMPIIVAEGPQRPTLTLFWQMMWQQEVSLVAMTTTISDGSQVVGERY
| . . .|.|| ||||| .. |||...|| | ..|.. |.|||....|. .. .|...||. |. ||.|.|.| |. . | |. . . ..|
llgslsvallpenleknRykd.ilpydhtRVkl..ddegsdYinAsyvdgydlkrkfIatqgPlpntvedFWrmvweqnvtvIvmltelvelgrekcaqy
WPSE-GDILEIGPLQITLEHEHT--NLAICERSLRVKHIDLGITRDVKLLQMLFWVAGEACEDSHRFLAFAERVRDARSKLKPDQPLLVHGITAVGRAGA
||.| |. |. |....|| .... . .. | |.|.... | .| |. .... | . |. .|.| |.||.....| .. | ||| |||.|.
wpleegesltygdftvtllsvevvllddytlrtlevtdtgngesrtvthfhytgwpdhgvpespaslldfielvrkvlkllpsggpvlVHCsaGvgRsgt
FCALLNLLDRFD---NERRLNVVDELTRLRQARSHFISDVVYLETILACVLDYAANKD
|.|. .|.... |....... . ||. | . . . .. . ..|.. .|.
fiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyeallellkkkl
|
|||||||||
| 0043336 | (Phosphotyrosine protein) phosphatases II | 492-738 | 3.2e-45 | 150.1 | In-house | 33-276 (278) | alignment | ||
Range on Protein: 492-738
Range on HMM: 33-276/278.0
LTYQYQTAMLPHNLEKNVRRNtLLPYEYNRVLLANPGEK--DQYYNASFIPTYSPQMPIIVAEGPQRPTLTLFWQMMWQQEVSLVAMTTTISDGSQVVGE
.. | .|.||.| .|| .. |||...|| | . |. . |.|||....|. .. .|.. ||. |. ||.|.|.. |. . | |. . ..|
kldtysiallpenkdknrykd.ilpydhsrvklsllggdldsdYinAsyvdgynvprkfiatqgPlpetvedFwrmvwelgvttivmLtelvelgrvkca
RYWPseGDILEIGPLQITLEHEHTNLAICERSLRVKHIDLGITRDVKLLQMLFWVAGEACEDSHRFLAFAERVRDARSklKPDQPLLVHGITAVGRAGAF
.||| |. |..|....|| |... .. | |.|.. | .| | .. | | ....|. .| | ..||.|.. ... |.||| |||.|.|
qYwp..ggsltygdftvtllkeehlddytvrtlevtnlgdgesrtvthyhylgwpdhgvpeslsllldflkavreale..dsngpvlVHCsaGvgRTGtf
CALLNLLDRFDNERRLNVVDELTRLRQARSHFISDVVYLETILACVLDY
.||. ||.....|..... . . .||. | . . ... . ..|.|
ialyllleqlekeggvdleeavkelreqRpgavqtpsqyrflyealley
|
|||||||||
| subfamily_PTPN1_pd | Subfamily PTPN1 | 492-725 | 1.5e-27 | 91.1 | In-house | 20-257 (290) | alignment | ||
Range on Protein: 492-725
Range on HMM: 20-257/290.0
LTYQYQTAMLPHNLEKNVRRNtLLPYEYNRVLLANpgEKDQYYNASFIPTYSPQMPIIVAEGPQRPTLTLFWQMMWQQEVSLVAMTTTISDGSQVVGERY
.. ..| ||.| ..| |. . ||.. |. | . .. .| |||.. . |.. || | . ||||.|.|. | | . . .|. .|
sdfptreaklpenrnlnryrd.vspydhsrikler..adndyinaslveleeakrsyiltqGPlpntvdhfWqmvWeqkskavvmlnkvvekeqikcaqy
WPSEGD--ILEIG--PLQITLEHEHTNLAICERSLRVKHIDLGITRDVKLLQMLFWVAGEACEDSHRFLAFAERVRDARSKLKPDQPLLVHGITAVGRAG
||.. . |.. |...| .|... | |... . ||.. . | | || | .||.. | . | ..| . .||.|
wPqgeeekellledtklkvkliseerksyytvrllelenlktqetreilhfhyttwpdfgvpespaaflkflfkvresGslssdvGpavihcsaGiGrsG
AFCA---LLNLLDRFDNERRLNVVDELTRLRQARSHFISDV
.|| .| |... |. ... . | ||. | .|
tfclvdtclvliekkddlssvdikkvllelrkyrlGliqta
|
|||||||||
| 0040438 | (Phosphotyrosine protein) phosphatases II | 493-749 | 3.1e-51 | 169.9 | In-house | 32-286 (317) | alignment | ||
Range on Protein: 493-749
Range on HMM: 32-286/317.0
TYQYQTAMLPHNLEKNVRRNtLLPYEYNRVLLANPGE--KDQYYNASFIPTYSPQMPIIVAEGPQRPTLTLFWQMMWQQEVSLVAMTTTISDGSQVVGER
. |..|.|| | .|| .. |||...|| | ..|. . |.|||...... .. .|.. ||. |. ||.|.|.| |... | |. . ... ..
ldtysvaelpenkdknrypd.ilpydhsRVkLsplggdldsdYInAsyvdgpnlkrkfIatqgPlpntvedFwrmvweqgvtvivmLteleelgrekcaq
YWPSeGDILEIGPLQITLEHEHTNLAICERSLRVKHIDLGITRDVKLLQMLFWVAGEACEDSHRFLAFAERVRDARSklKPDQPLLVHGITAVGRAGAFC
|||. |. |..|....|| |... |. | |.|.. . . .| |. .....| . . .. .|.| |.||.|.. .|. |.||| |||.|.|.
Ywpl.getltygdftvtllseeelagitlrtlevedlgdsesrtvthfhytgWpdhgvppspdllldfleavreale..dpggpvlVHCsaGvgRtGtfi
ALLNLLDRFDNERRLNVVDELTRLRQARSHFISDVVYLETILACVLDYAANKDKGLPLQ
|.. .|.... |....| . . .||..|.. . ... . ..|.| .|.. |..
aaylmleqlekeggvdveeavkelreqRpgavqtpeqyrflydalleylkrkltlepas
|
|||||||||
| 0051299 | (Phosphotyrosine protein) phosphatases II | 493-739 | 7.6e-51 | 168.6 | In-house | 38-286 (288) | alignment | ||
Range on Protein: 493-739
Range on HMM: 38-286/288.0
TYQYQTAMLPHNLEKNvRRNTLLPYEYNRVLLANPGE--KDQYYNASFIPTYSPQMPIIVAEGPQRPTLTLFWQMMWQQEVSLVAMTTTISDGSQVVGER
.... .|.||.||||| | .|||...|| | .... . |.|||.|..| .. |...|| |. ||.|.|.|.|... | |.. . ... ..
dltlsaallpenlekn.RysdilpydhsRVkLsvldgvegsdYinAsyidgynlkrkfIatqgPlpntvedFWrmvweqnvrvIvmltklvelgrekcaq
YWPSeGDILEIGPLQITLEHEHTNLAICERSLRVKHI----DLGITRDVKLLQMLFWVAGEACEDSHRFLAFAERVRDARSklKPDQPLLVHGITAVGRA
|||. |. |..|....|| .|... .. | |.|... | .| |. .... | . .. .|.| ..||.|.. ... | .|| |||.
Ywpl.ggsltygditvtllseevlddytvrtlevtnldlldgdgesrtvthfhytnwpdhgvpdspellldflrlvrkala..sgggpvvVHCsaGvgRt
GAFCALLNLLDRFDNERRLNVVDELTRLRQARSHFISDVVYLETILACVLDYA
|.|.||. ||.....|....| . . |||. | . . . .. . ..|.|.
gtfialdllleqlekeggvdvleavkrlreqRpgmvqtpeqyrfvyealleyl
|
|||||||||
| 0047943 | (Phosphotyrosine protein) phosphatases II | 493-738 | 1.1e-50 | 168.0 | In-house | 27-271 (273) | alignment | ||
Range on Protein: 493-738
Range on HMM: 27-271/273.0
TYQYQTAMLPHNLEKNVRRNtLLPYEYNRVLLanPGEKDQYYNASFIPTYSPQMPIIVAEGPQRPTLTLFWQMMWQQEVSLVAMTTTISDGSQVVGERYW
. |..|.||.|..|| .. .|||...|| | ..... |.|||....| .. .|...|| |. ||.|.|.| |... | |.. . ... ..||
lltysvallpenkdknrykd.ilpydhsrvkl..gdggsdyinAsyvdgynlkrkfiatqgPlpntvedfwrmvweqnvrviVmLtelvelgrekcaqYw
PSEGD--ILEIGPLQITLEHEHTNLAICERSLRVKHIDLGITRDVKLLQMLFWVAGEACEDSHRFLAFAERVRDARSKLKPDQPLLVHGITAVGRAGAFC
|.||. |. |....|| |.|. .. | |...... | .| |. .... | .... .| | | ||.|...|. . | .|| |||.|.|.
pleggelsltygkftvtllseetkddytvrtleltnlgtgesrtvthfhytgwpdhgvppslesllefielvrkalealpsngpvvVHCsaGvgRtgtfi
ALLNLLDRFDNERRLNVVDELTRLRQARSHFISDVVYLETILACVLDY
||. |||.. |....| . . .||. | . . . ... . ..|.|
aldllldqlekeggvdvleavkllrsqRpgmvqtpeqyrflyealley
|
|||||||||
| 0045450 | (Phosphotyrosine protein) phosphatases II | 493-739 | 7.3e-47 | 155.9 | In-house | 44-304 (307) | alignment | ||
Range on Protein: 493-739
Range on HMM: 44-304/307.0
TYQYQTAMLPHNLEKNVRRNtLLPYEYNRVLLANPGEK---DQYYNASFI--------PTYSPQMPIIVAEGPQRPTLTLFWQMMWQQEVSLVAMTTTIS
. | .|.||.| .|| .. |||...|| | ..... . |.|||.. ..| .. .|.. ||. |. ||.|.|.| |... | |.
lgeysiallpenkdknrykd.ilpydhtRVklssldgsledsdYiNAsyvrvpllllldgydlkrkfIatqgPlpetvedFwrmlweqgvtvivmltelv
DGSQVVGERYWPSEGDILEIGPLQITLEHEHTNLAICERSLRVKHI-DLGITRDVKLLQMLFWVAGEACEDSHRFLAFAERVRDARSKLKPDQPLLVHGI
. .. .|||.||. |..|....|| |.. .. | |.|.. | .| |. .... | . .... .|.| |.||.|...|... | |||
elgrekcaqywPdegeeltygnftvtllseehldgytvrtlevtdldgtgesrtvthfhytgwpdhgvppsfeelldfieevrkaleelpkggpvlVHCs
TAVGRAGAFCALLNLLDRFDNERR---LNVVDELTRLRQARSHFISDVVYLETILACVLDYA
|||.|.|.|.. .|.....| ... . . .||. |.. . ... . ..|..
aGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrflyeallell
|
|||||||||
| subfamily_PTPRG_pd | Subfamily PTPRG | 493-724 | 7.3e-32 | 105.3 | In-house | 36-272 (563) | alignment | ||
Range on Protein: 493-724
Range on HMM: 36-272/563.0
TYQYQTAMLPHNLEKNvRRNTLLPYEYNRVLLAN-PGEKDQ--YYNASFIPTYSPQMPIIVAEGPQRPTLTLFWQMMWQQEVSLVAMTTTISDGSQVVGE
. ..... |.| .|| | ...|. || |.. ||.|.. | ||..| | . |.. || . |. ||.|.|.|.|... | | . . . .
dldaehsqkpenkrKn.RylnivaydrsRvklsplpgkkkklDYinAnyidGyqkskafiatqgplkdtfddFWrmiWeqnvaiivmitnlvergrrkcd
RYWPSeGDILEIGPLQITLEHEHTNLAICERSLRVKHIDLGITRD------VKLLQMLFWVAGEACEDSHRFLAFAERVrdARSKLKPDQPLLVHGITAV
.|||. . ...| ||.||..|.. .|.| .|.. | ... |. .. | . | | | |... .... . |..|| . |
vYWPk.desetygalqvtlieeevlalytvrtlviknlklkkkkqcdteklvrqyhytkWPdhgvPehslpvLifvkks..saankaeaGPivvHcsaGv
GRAGAFCALLNLLDRFDNERRLNVVDELTRLRQARSHFISD
||.| ...| || . .| || . | ..| | . . .
grtGtyivldtllkqiqqenavnvfgflkhiraqRnflvqt
|
|||||||||
| subfamily_PTPN12_pd | Subfamily PTPN12 | 493-738 | 2.8e-30 | 100.2 | In-house | 29-276 (290) | alignment | ||
Range on Protein: 493-738
Range on HMM: 29-276/290.0
TYQYQTAMLPHNLEKNvRRNTLLPYEYNRVLLANPGEKD--QYYNASFIPTYSPQMPIIVAEGPQRPTLTLFWQMMWQQEVSLVAMTTTISDGSQVVGER
.|. ... ..| .|| | .|||...|| | . |.. .| ||.|| . .. | | || ||. ||.|.|...|..| | . . . ||
vysteagekeenvkkn.rykDilPydksrvelskieeeegsdYinanfikgvegkleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkkCer
YWPSEGDI-LEIGPLQITLEHEHTNL-AICERSLRVKHIdlGITRDVKLLQMLFWVAGEACEDSHRFLAFAERVRDARSklKPDQPLLVHGITAVGRAGA
|||.||. ||.|....|||.|.. . |.|.|.. . .| |. .. | . . .. |.. | ||. .. . |.||.|| |||.|.
YWpeegeeelefgefevtleeekavdddflirtLkveaq..kesrkvyqfhYtaWPDhgvPssaksllelielvrelqe..sedaPlvvhCsaGvGrtGt
FCALL---NLLDRFDNERRLNVVDELTRLRQARSHFISDVVYLETILACVLDY
.|. .|| . . .|.| | ...||. |. . | . .|...
iiaidyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavael
|
|||||||||
| subfamily_Sponge-PTP6_pd | Subfamily Sponge-PTP6 | 493-736 | 1.5e-16 | 54.9 | In-house | 35-276 (439) | alignment | ||
Range on Protein: 493-736
Range on HMM: 35-276/439.0
TYQYQTAMLPHNLEKN-VRRNTLLPYEYNRVLL-ANPGE-KDQYYNASFIPTYSPQMPIIVAEGPQRPTLTLFWQMMWQQEVSLVAMTTTISDGSQvvge
|. ..... .. .. | . . .... || | || . .|.|| .| | . | ..||.. | ||...... .. . | | . . .
dyaciaslaaqeydqtknrykdvgafdhtrvtlqeipgvphshyinanyikGyyddklyiatqgpkkettddfwrlviekktvtivmltnlvesyk....
rYWPSEGDILeIGPLQITLEHEHTNLAICERSLRVKHIDLGITRDVKLLQ--MLFWVAGEACEDSHRFLAFAERVRDARSKlKPDQPLLVHGITAVGRAG
||||.... | . . ... . | ..| .. .|| . | . .. | | . | | . |..|| . |||.|
.ywpsdaevc.ygdiavrvdrnielpnyvirgfkvfnerdttekertvlqfhyiawpdknvpaqashvldflrainsandk.eeygpvvvhcsagvGrtG
AFCALLNLLDRFDNERRLNVVDELTRLRQARSHFISDVVYLETILACVL
. || |... | .... .. ||. | ... ... | .||
tiialdialeqlklenkvdikgivkvlrkqrkqmvqalcqyvfiynavl
|
|||||||||
| 0039614 | (Phosphotyrosine protein) phosphatases II | 494-743 | 6.7e-45 | 149.2 | In-house | 46-293 (297) | alignment | ||
Range on Protein: 494-743
Range on HMM: 46-293/297.0
YQYQTAMLPHNLEKNVRRNtLLPYEYNRVLLANPGEK---DQYYNASFIPTYSP-QMPIIVAEGPQRPTLTLFWQMMWQQEVSLVAMTTTISDGSQvVGE
| .|.|| | .|| .. |||...|| | ... . |.|||....|. .. .|.. ||. |. ||.|.|.| |. . | |. . .. .
pdysiallpenkdknrykd.ilpydhsrvklkpedgvdldsdYinAsyvdgydlltrkfIatqgPlpetvedFwrmvweqgvtvivmLtklvelgr.kca
RYWPSEGDilEIGPLQITLEHEHTNLAICERSLRVKHidLGITRDVKLLQMLFWVAGEACEDSHRFLAFAERVRDARSKLKPDQPLLVHGITAVGRAGAF
.|||.||. . |....|| .... .. | |.|.. | .| |. .| . | . ..... .| | | ||.|...|... | ||| |||.|.|
qywpeegg..tygdftvtllkvehldgytvrtlevtn..ngesrtvthfqytgwpdhgvppslellleflelvrealaelpkggpvlVHCsaGvgRtGtf
CALLNLLDRFDNERRLNVVDELTRLRQARSHFISDVVYLETILACVLDYAANKD
.|.. .|.... |....| . . .||..|.. . ... . ..|.. .|.
iaaylmleqlekeggvdvleavkelreqRpgavqtpsqyrflydallellkrkl
|
|||||||||
| 0045098 | (Phosphotyrosine protein) phosphatases II | 494-739 | 3.3e-41 | 136.9 | In-house | 23-272 (278) | alignment | ||
Range on Protein: 494-739
Range on HMM: 23-272/278.0
YQYQTAMLPHNLEKNvRRNTLLPYEYNRVLlanpgekDqYYNASFIPTYspQMPIIVAEGPQRPTLTLFWQMMWQQEVSLVAMTTTISDGSQVVGERYWP
... .|... ||.|| | |||...|| | | |||.|..| .. |.. || |. ||.|.|.. .. . | |. ..... ..|||
seitpalylgnldkn.RykdilpydhsrVk.......d.YINAsyidgy..pkkfIatqgPlpstvadfwrmlwelgitvivmltelvelgrekcaqywp
SeGDILEIGPLQITLEHEHTNLAICERSLRVKHI----DLGITRDVKLLQMLFWVAGEACEDS--HRFLAFAERVRDARS-----------KLKPDQPLL
. |. |..|....||. |... .. | |.| .. . .| |. |..|.| ... ... || . |..|.|.. | .. | |
e.ggsltygdftvtllseevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllsslllldsggpvl
VHGITAVGRAGAFCALLNLLDRFdnERRLNVVDELTRLRQARSH-FISDVVYLETILACVLDYA
|| |||.|...|. .|... |..... . .. ||. | . . .. . ..|..
VHCsaGvgRtGtlvaaylmlell..eggvdlleavkelrsqRpglavqnleqyrflyefllell
|
|||||||||
| subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 494-724 | 1.7e-29 | 97.7 | In-house | 34-262 (315) | alignment | ||
Range on Protein: 494-724
Range on HMM: 34-262/315.0
YQYQTAMLPHNLEKNVRRNtLLPYEYNRVLL--ANPGEKDQYYNASFIPTYSPQMPIIVAEGPQRPTLTLFWQMMWQQEVSLVAMTTTISDGSQVVGERY
|. ..| . | .|| .| ||.. .|| | . .. |.|||.|... . | . ||.. .. ||.|..|..|. ..| | ..| .. .|
yrqrvaretinfkknrykn.ilPldsarvkleviddsPdsdyinasyiksvdddkayiasqgPlkasvddfwrmvlqekvttivmvtkkqegdkikcrqy
WPS-EGDILEIGPLQITLEHEHTNLAICERSLRVKHIDlgITRDVKLLQMLFWVAGEACEDSHRFLAFAERVRDArsKLKPDQPLLVHGITAVGRAGAFC
|| ..| | | ....| ... | | ... . .| | |. | . ... .| . |. . | . .|||| . |||.| ..
wPdrkadsvefGsikvellsleadtdgvarklvtrkse..esrtvtqfqftewPdkGvdkqtssllklikevkad..ngkkefsllvhcsaGvGrtGvvi
ALLNLLDRFDNERRLNVVDELTRLRQARSHFISD
.. . ... ..| ..| . .. ||. | ...
sidevvaqikrtrsvdvfnfvknlrakrpylvqt
|
|||||||||
| subfamily_Urchin-PTP-4_pd | Subfamily Urchin-PTP-4 | 494-737 | 1.4e-18 | 61.5 | In-house | 35-234 (392) | alignment | ||
Range on Protein: 494-737
Range on HMM: 35-234/392.0
YQYQTAMLPHNLEKNVRRNtLLPYEYNRVLL--ANPGEKDQYYNASFIPTYSPQMPIIVAEGPQRPTLTLFWQMMWQQEVSLVAMTTTISDGSqvvgery
|. ..| . ||.|| .| |||. .|| | . ...|.|||.||.. . | ..||. .| ||.|..|..|. .|| | . .|
ypqtvaqkeinlkknrykn.ilpydsarvkleviddipdsdylnasyipsfdnekayiasqgpnaaslddfwrmvfqenvttiamvtklkegd.......
wpsegdileigplqitlehehtnlaicerslrvkhidL-GITRDVKLLQMLFWVAGEACEDSHRFLAFAERVRDARSKLKpdQPLLVHGITAVGRAGAFC
.| | .. | . . . .| | . |. . .||..| ..|||.|
.....................................kgddartvaqfhftewPdkdvpkhtssllkfikevkadfGqyt..hpliihcsagvgrtgvvi
ALLNLLDRFDNERRLNVVDELTRLRQARSHFISDVVYLETILACVLD
.. ... . . | ..|.. .| .|. | ... | ..||.
sidsvvahakktrmvdvfnfvtnirrkrpymvqtkeqyafiygavle
|
|||||||||
| subfamily_PTPRD_pd | Subfamily PTPRD | 495-724 | 3.5e-43 | 143.1 | In-house | 39-266 (564) | alignment | ||
Range on Protein: 495-724
Range on HMM: 39-266/564.0
QYQTAMLPHNLEKNvRRNTLLPYEYNRVLLAN-PG-EKDQYYNASFIPTYSPQMPIIVAEGPQRPTLTLFWQMMWQQEVSLVAMTTTISDGSQVVGERYW
. ..| |.| .|| | . ..|. .|| | . .| |. | ||||| .| . | . || .|. ||.|.|.|..| . | | ... ..| ..||
tweaankpaNkaKN.RyanivaYdhsRVvLskvegdegsDYINAsfidgyrkrkayIAtqgPlaetiedFWRmvweqnsstiVmltkleEkgkvkchkYW
PSEGdILEIGPLQITLEHEHTNLAICERSLRVKHIDLGITRDVKLLQMLFWVAGEACEDSHRFLAFAERVRDARSklKPDQPLLVHGITAVGRAGAFCAL
|..| ..| |..|||.|.. .. |....|. . .| |. . | . | .|.. ..||.... . .|..|| ||| |.|...
Pekg.tetygeltVtleeeeeladyeirtfklkkkkssesreVrqFhFtsWPdhgvpesatslLdlirkvralne..pdagPivVhCSaGVGRTGtfivi
LNLLDRFDNERRLNVVDELTRLRQARSHFISD
.|.| .|. ... ...||. | . .
damlerikeektvDiyqyvkalrkqRnamVqt
|
|||||||||
| 0040439 | (Phosphotyrosine protein) phosphatases II | 495-739 | 5.2e-43 | 142.8 | In-house | 2-246 (249) | alignment | ||
Range on Protein: 495-739
Range on HMM: 2-246/249.0
QYQTAMLPHNLEKNVRRNtLLPYEYNRVLLANPGE--KDQYYNASFIPTYSPQMPIIVAEGPQRPTLTLFWQMMWQQEVSLVAMTTTISDGSQVVGERYW
.| .|.|| |..|| .. |||...|| | .. . |.|||.|..| .. .|.. || |. ||.|.|.. .. . | |. .. ..||
eysvallpenkdknrypd.ilpydhsrvklsilpglflsdyinAsyidgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqyw
PSeGDILEIGPLQITLEHEHTNLAICERSLRVKHIDLGITRDVKLLQMLFWVAGEACEDSHRFLAFAERVRDARSKLKPDQPLLVHGITAVGRAGAFCAL
|. |. ||.| ...|| ..... .. | |..... | .| |. .|.. | .... .|.| |.||.|...|... |.||| |||.|.|.|.
pl.ggsleygdftvtllsvevkddytvrtleltnlydgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtfiaa
LNLLDRFDNERRLNVVDELTRLRQARSHFISDVVYLETILACVLDYA
. .|.... |..... . . ||..|.. . ... .. ..|..
ylmleqlekelgvdleeavkllrsqRpgavqnpeqyrflyeallell
|
|||||||||
| subfamily_PTPRB_pd | Subfamily PTPRB | 495-742 | 1.8e-38 | 127.2 | In-house | 42-288 (293) | alignment | ||
Range on Protein: 495-742
Range on HMM: 42-288/293.0
QYQTAMLPHNLEKNVRRNtLLPYEYNRVLLANP--GEKDQYYNASFIPTYSPQMPIIVAEGPQRPTLTLFWQMMWQQEVSLVAMTTTISDGSQVVGERYW
. ..| |. | .|| .| .|||...|| ||. ... | ||..|| |. . |.. || |. ||.|.|....| . | | . .. .| |.||
avkaaelavnraknrytn.ilpydhsrvkLaalkdesgsDYinanyipgynsprefiatqGPlpetvddfWrmvwekkssiivmltqlvekgkvkCeeYW
PSEGDILEIGPLQITLEHEHTNLAICERSLRVKHidLGITRDVKLLQMLFWVAGEACEDSHRFLAFAERVRDARSKLKPDQPLLVHGITAVGRAGAFCAL
|.. . | ...|| .|.. |.|.... .|.|. .. . |. . |... .|.| ..||.| .| . ..|..|| |||.|.| ||
PadeepvlyGdikvtlvaeeeledwvirelkiek..ekeerkvrqyhftsWpdhgvPektktlldfvrtvreaiektaskrPivvhCsaGvGRtGtfial
LNLLDRFDNERRLNVVDELTRLRQARSHFISDVVYLETILACVLDYAANK
.||.. ..| .... ...||. | ... . | ||||. .|
drllqaieeedyvdifgivaelReeRnllvqtekqYifihqcvldllrkk
|
|||||||||
| subfamily_PTPN14_pd | Subfamily PTPN14 | 495-738 | 2.2e-37 | 123.7 | In-house | 40-295 (300) | alignment | ||
Range on Protein: 495-738
Range on HMM: 40-295/300.0
QYQTAMLPHNLEKNVRRNtLLPYEYNRVLLAN-PGEKDQYYNASFIPT--YSPQMPIIVAEGPQRPTLTLFWQMMWQQEVSLVAMTTTISDGSQVVGERY
...|| || | ||| .. .|||| ||| |. ....| ||| | . . .. ||| ||.. |.. ||||.|.|.|.|..| | . .. . .|
llstaklpenaeknrfkd.vlPyednrvelsptkenstgyinassikvsvggkersyivaqgPleltvqdfWqmvWeqgvqlivmlteeeedgkeksfky
WPSE---GDILEIGPLQITLEHEHTNLAICERSLRVKHIDLGITRDVKLLQMLFWVAGEACEDSHRFLAFAERVRDARSKLKPDQ-------PLLVHGIT
.|.. . .| | ..| . .. .. ..|..||. . |.| || | . || . || . |.|. | | . . |.|||
fPkleskkktvefgkfkvttkfsedsdsvittglklkhlpskeertvwhlqytDWpdhgvPeDvkgflsyLeevqsvrrktnseveskeskPPvlvhCsa
AVGRAGAFCALLNLLDRFDNERRLNVVDELTRLRQARSHFISDVVYLETILACVLDY
|||.| |. ......... |.|||. | .... . . . .. |
GvGrtGvlilsdlliatlehneeidikkvlarLreqrmllvqtlaqYkfvYkvliky
|
|||||||||
| subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 495-743 | 7.1e-35 | 115.6 | In-house | 39-287 (319) | alignment | ||
Range on Protein: 495-743
Range on HMM: 39-287/319.0
QYQTAMLPHNLEKNvRRNTLLPYEYNRVLLAN-PGE-KDQYYNASFIPTYSPQMPIIVAEGPQRPTLTLFWQMMWQQEVSLVAMTTTISDGSQVVGERYW
....| ..| .|| | . .|.|. || |.. .| . .| ||||| .| . | . .| |. ||.|.|..|.| | | | ... .| ..||
tfdsaskeenkkkn.ryqnilaydrtrvvlseldgvegsdyinasfidgyqerekfiatqaPlentiedfWrmvWeeessivvmltklveklkvklkkyw
PSEgDILEIGPLQITLEHEHTNLAICERSLRVKHIDLGI-TRDVKLLQMLFWVAGEACEDSHRFLAFAERVRDARSKLKpDQPLLVHGITAVGRAGAFCA
|.| .. | | | .|||.|. . | | ... . ||.|| | . | . |.. |.. .|.| .|.| . ..|. || ||| |.|..
pee.nfeeyGrlivtleeeeeledyiirklklnkkssevetRevkhfqyteWpdhdvPekatslldllkrirksrektq.sgPivvhCsaGvGRtGtfiv
LLNLLDRFDNERRLNVVDELTRLRQARSHFISDVVYLETILACVLDYAANKD
| |.| .| |.| ||| | .. . | .|... |
ldamlervkeegvlDvfstvsrlRtqRnimvqrpeqYkfiyealleaveagd
|
|||||||||
| subfamily_PTPRA_pd | Subfamily PTPRA | 495-745 | 1.2e-33 | 111.4 | In-house | 49-301 (330) | alignment | ||
Range on Protein: 495-745
Range on HMM: 49-301/330.0
QYQTAMLPHNLEKNvRRNTLLPYEYNRVLLANP-G-EKDQYYNASFIPTYSPQMPIIVAEGPQRPTLTLFWQMMWQQEVSLVAMTTTISDGSQVVGERYW
...| | ||| | .|||...|| |.. | |. | ||||| | . | | ||.. |. ||.|.|.|. . . | | . . . ..||
tlelaskeenkekn.rvvnilPydfsrvilsvkeGveesdyinasfidGykekdkfiaaqGPkeetvedfwrmiweqksativmltelkerkeekcaqyw
PSEGdILEIGPLQITLEHEHTNLAICERSLRVKHIDLGI----TRDVKLLQMLFWVAGEACEDSHRFLAFAERVRDARSKLKPdqPLLVHGITAVGRAGA
|.|| .. | .....|.| .. | . |... . .| |. . . | .. | . ..|. . . |. || . |||.|.
PdeG.lvtyGnirvevedetvlvdytvrkflvqqlpdatrekksrlvrqfhftswPdvGvPfepiGmlkllkkvkklnqqsag..pivvhcsaGvGrtGt
FCALLNLLDRFDNERRLNVVDELTRLRQARSHFISDVVYLETILACVLDYAANKDKG
|..| ..|.| ||...| . . |||. |.. . | | .|.| |
fivldavlervkaerkvdvfefvkrlrlqrpqmvqtdeqyefiykvlleyylygdte
|
|||||||||
| subfamily_PTPN9_pd | Subfamily PTPN9 | 495-743 | 5.2e-32 | 106.0 | In-house | 33-294 (297) | alignment | ||
Range on Protein: 495-743
Range on HMM: 33-294/297.0
QYQTAMLPHNLEKNvRRNTLLPYEYNRVLLANPGEKD--QYYNASFIPTYSPQMPIIVAEGPQRPTLTLFWQMMWQQEVSLVAMTTTISDGSQVVGERYW
......|. ||||| | . .| |. || ||. |.. | ||.|. | . .| . || . | . ||.|.|.||| . ||| . . .. .||
tflasklranlekn.rytdvlcydetrvvlakvdedeasdyinanfvdGykqkkafiatqGplkktvsdfWrmvWeqevlvivmttrvvergrlkcgqyW
P-SEGDILEIGPLQITLEHEHTNLAICERSLRVKHIDLGITRDVKLLQMLFWVAGEACEDSHRFLAFAERVRDARSKL----------K-PDQPLLVHGI
| .|.. | | |... . ... . .|.| .|... . .| | |.| | .... .| . | ||...... . . |..||
pleeessaefgdlsvsnveveeeedykvrvleiknvkteesrkvthfqflsWPdyGvPssaaslldvlekvrekqalavkelgdewkghpsgPPivvhcs
TAVGRAGAFCALLNLLDRFDNERRLNVVDELTRLRQARSHFISDVVYLETILACVLDYAANKD
. .||.|.|..| |.|.... ..||. . .||. |.. | | .||.|| ...
aGiGrtGtfitldiclsrleevgtvdvvetvkllrtqrafsiqtpeqyefcylavleyalelk
|
|||||||||
| subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 495-739 | 2.5e-29 | 97.4 | In-house | 39-288 (325) | alignment | ||
Range on Protein: 495-739
Range on HMM: 39-288/325.0
QYQTAMLPHNLEKNVRRNtLLPYEYNRVLLANPGEK--DQYYNASFIPTYSPQMPIIVAEGPQRPTLTLFWQMM--WQqevSLVAMTTTISDGSQVVGER
...||.|.| .|| .| ..... .|| | ... |.|||.. .. . . | |. |. .|... |. . | . . . |. .
akkvamkpenkaknrfkn.vvaldksrvvletkkddpssdyinasylrddkkkdvflaaqaPltatindlWrlvldWr...csvvvvlneldlgkdrcav
YWPSE-GDILEIGPLQITLEHEHTNLAICERSLRVKHIDLGITRDVKLLQMLFWVAGEACEDSHRFLAFAERVRDARS----KLKPDQPLLVHGITAVGR
||| | |. . |.|.. | . | | || .. | || || .|. | . .... . | . | |.||| .. |||
ywpkemgksktfGglevklrtieeisdyvhrvldvkqvkkGetrsvkqfqlqswddmGvqkrpatlisilqlvkavservtantkastpilvhcsaGvGr
AGAFCALLNLLDRFDNERRLNVVDELTRLRQARSHFISDVVYLETILACVLDYA
.|.| .| .|.. .| |... . . .||. | . | | .. ..
tGvfislysalakvieesrvdifgfvkklrkdrpsmvetvdqyiliyealveay
|
|||||||||
| subfamily_PTPN3_pd | Subfamily PTPN3 | 496-736 | 3.1e-38 | 126.3 | In-house | 33-272 (280) | alignment | ||
Range on Protein: 496-736
Range on HMM: 33-272/280.0
YQTAMLPHNLEKNVRRNtLLPYEYNRVLLANPGEkdQYYNASFIPTYSPQMP----IIVAEGPQRPTLTLFWQMMWQQEVSLVAMTTTISDGSQVVGERY
..| .|.||.|| |. .|||. || | . | ||... .| . |.. || . | | ||||.|.|..||. | ||. . .| .|
isaarkpenlsknryrd.ilpydatrvklkeset..dyinanyvnmeipstglvnryiatqGPlaktatdfWqmvweqksslivmlttlverGrvkChqy
WPSEGDILEIGPLQITLEHEHTNLAICERSLRVKHIDLGITRDVKLLQMLFWVAGEACEDSHRFLAFAERVRDARSKlkPDQPLLVHGITAVGRAGAFCA
||...| || | .....|.|... ... | | .|. . | . || | | . .||. || | ||||..|| ..|..|| . .||.| . .
WPetedeleygefsvkcekedetksyvlrelvlkdketkeerkilqlqylaWpdhgvPddsadflefvervrklrsg..keePvvvhCsaGigrtGvlil
LLNLLDRFDNERRLNVVDELTRLRQARSHFISDVVYLETILACVL
| | .... ....| . ..|. |. .. . . . ..|
letalalieaaepvypldivrtmrdqramlvqtasqykfvCeail
|
|||||||||
| subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 496-739 | 2.8e-35 | 116.8 | In-house | 39-279 (288) | alignment | ||
Range on Protein: 496-739
Range on HMM: 39-279/288.0
YQTAMLPHNLEKNVRRNtLLPYEYNRVLLAN--PGEKDQYYNASFIPTYSPQMPIIVAEGPQRPTLTLFWQMMWQQEVSLVAMTTTISDGSQVVGERYWP
... |..| .|| || |||...|| | . ... | |||.| . . | . || |. ||........| ..| | . .| . |.|||
vtagrlavnakknRyrn.ilpyDekrvklkkleeeagaDYinasyidgekkkkkyiatqgPladtvndfWelvyenktstivmltelveggktkCeeYWP
SEGDILEIGPLQITLEHEHTNLAICERSLRVKhiDLGITRDVKLLQMLFWVAGEACEDSHRFLAFAERVRDARSKLkpDQPLLVHGITAVGRAGAFCALL
.... . | ...|| .... . .|.| .. . .... .| | |. . |... .|.. . | | .. .|..|| |||.| | ||
dadkpknyGsvtvtlveskeledfvlrkllle..kkkteleitqyqylaWpdhgvPeskapllellrqvkvanqad..tgpiivhCsaGvGrtgtFiald
NLLDRFDNERRLNVVDELTRLRQARSHFISDVVYLETILACVLDYA
.|.|. ..| ..|.. ...||. | .. . | | ..|. .
alidaveeedyiDvagtvaklRkqRallvqtlkqYefiyevllsli
|
|||||||||
| subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 496-736 | 1.4e-34 | 114.6 | In-house | 38-277 (318) | alignment | ||
Range on Protein: 496-736
Range on HMM: 38-277/318.0
YQTAMLPHNLEKNvRRNTLLPYEYNRVLLANPG--EKDQYYNASFIPTYSPQMPIIVAEGPQRPTLTLFWQMMWQQEVSLVAMTTTISDGSQVVGERYWP
.. | | || | . .|.|. ||.| . |. | ||..|. | . | | .| |.. ||.|.|.|. ... | | ... ... .||||
slkslepvnkakn.ryanilaydhtrvkLqmlegeegsDyinanyidGyrrkkayiaaqaPlpetieDfWrmvWeqnsavivmltqeeergkakvhryWP
SEGDIlEIGPLQITLEHEHTNLAICERSLRVKHIDLGITRDVKLLQMLFWVAGEACEDSHRFLAFAERVRDARSKlKPDQPLLVHGITAVGRAGAFCALL
|.| . ..| |...|..| . |...|.. . .|.|. .. | |.. .|.. .|. | | . .|..|| . |||.| |.|.
skgsr.sygklvvelkeevelsdyvlrefkvtrteeeesrqvrqyhytsWpdegvpesgaslldlvrqvskaqqk.sgagpivvhCsaGvGrtGvfiavd
NLLDRFDNERRLNVVDELTRLRQARSHFISDVVYLETILACVL
||.| .| ..| . ..||. | . | | .|
illerikaealvDvfqtvkqlreqrnlmvqtedqyefiydvll
|
|||||||||
| subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 496-737 | 7e-30 | 99.4 | In-house | 53-289 (319) | alignment | ||
Range on Protein: 496-737
Range on HMM: 53-289/319.0
YQTAMLPHNLEKNvRRNTLLPYEYNRVLLAN--PGEKDQYYNASFIPTYSPQMPIIVAEGPQRPTLTLFWQMMWQQEVSLVAMTTtisdgsQVVGERYWP
. | |..| .|| | .|... |.| | . | | ||||. | . | | ||. || ||.|.|....| . . | . .|||
qtfanldqnkdkn.riinilafdknvvklerliGeefsdyinasfvtGyqrkdkyiaaqGPldntladfWrmiweyncstivllt......kdkcsqywp
SEGDIL-EIGPLQITLEHEHTNLAIceRSLRVKH-IDLGITRDVKLLQMLFWVAGEACEDSHRFLAFAERVRDARSKLKPDQPLLVHGITAVGRAGAFCA
...| | . ..... .| . .. |.... . |... .| | . . .. . ..|| .|| . ....|| . |||.|.. .
lkivikeerfkvkvdsveetaeyvv..rdielsedgkekdirkitqfhflGwpdvGvpdypsdlmrlvkkvrhltskenhranivvhcsaGvGrtGvyiv
LLNLLDRFDNERRLNVVDELTRLRQARSHFISDVVYLETILACVLD
| ||||...|....| . . ||| |.... |.| | . .|.
ldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysalle
|
|||||||||
| subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 496-737 | 7.1e-30 | 99.5 | In-house | 17-253 (284) | alignment | ||
Range on Protein: 496-737
Range on HMM: 17-253/284.0
YQTAMLPHNLEKNvRRNTLLPYEYNRVLLAN--PGEKDQYYNASFIPTYSPQMPIIVAEGPQRPTLTLFWQMMWQQEVSLVAMTTtisdgsQVVGERYWP
. | |..| .|| | .|... |.| | . | | ||||| | . | . ||. || ||.|.|....| . . | . .|||
qtfanldqnkdkn.righilafdknvvklerliGeefsdyinasfitGyqrkdkyiatqGPldntladfWrmiweyncstivllt......kdkcsqywp
SEGDIL-EIGPLQITLEHEHTNLAIceRSLRVKH-IDLGITRDVKLLQMLFWVAGEACEDSHRFLAFAERVRDARSKLKPDQPLLVHGITAVGRAGAFCA
...| | . ..... .| . .. |.... . |... .| | . . .... ..|| .|| . ....|| . |||.|.. .
lkivikeerfkvkvdsveeseeyvv..rdielsedgkekdirkirqfhflgwpdvgvpdypsdlmrlvkkvrhltskenhranivvhcsagvgrtgvyiv
LLNLLDRFDNERRLNVVDELTRLRQARSHFISDVVYLETILACVLD
| ||||...|....| . . ||| |.... |.| | . .|.
ldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysalle
|
|||||||||
| subfamily_egg_pd | Subfamily egg | 496-692 | 3.5e-07 | 24.2 | In-house | 32-221 (307) | alignment | ||
Range on Protein: 496-692
Range on HMM: 32-221/307.0
YQTAMLPHNLEKnVRRNTLLPYEYNRVLLANPG--EKDQYYNASFIPTYSPQMPIIVAEGPQRPTLTLFWQMMWQQEVSLVAMTTTISDGSQVvgERYWP
..||. |||| .| . . .. || | . |.. | . |.|. | . | ||.|..|.|| . | |. . . | |||
lttaasdnnlek.arskrvhckdssrvklelrrGqylddfihanrvkGkpllnefilaqaplkntvddfwrmvfqeevqyivmltsrkeserc..eyywp
-SEGDILEI--GPLQITLehEHTNlAICERSLRVKHIDLgITRDVKLLQMLFWVaGEACEDSHRFLAFaERVRDARSKlkpDQPLLVHGITAVGRAGAFC
.| | | . | |.|. . . . .|| .. | . | . . . | |. . |. . . . .| .| .| .|. | | .|...
kaesdslvtvpGslrien..lkvd.skadplfrvtklkl.vGgddeerflehwq.gdvnnssdvyspl.rvlrklrnl...skpvvvqdilGvskaatlv
AL
|.
ai
|
|||||||||
| 0042113 | (Phosphotyrosine protein) phosphatases II | 497-738 | 3e-41 | 136.8 | In-house | 2-242 (245) | alignment | ||
Range on Protein: 497-738
Range on HMM: 2-242/245.0
QTAMLPHNLEKNVRRNtLLPYEYNRVLLANPGEK--DQYYNASFIPTYSPQMPIIVAEGPQRPTLTLFWQMMWQQEVSLVAMTTTISDGSQVVGERYWPS
..|.||.| .|| .. |||...|| | ..|. . |.|||....| .|.. ||.. |. ||.|.|.. .. . | |. . ..| ..|||.
svallpenkdknrysd.ilpydhtrvklspdggdldsdyinasyvdgyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywpl
eGDILEIGPLQITLEHEHTNLAICERSLRVKHIDLGITRDVKLLQMLFWVAGEACEDSHRFLAFAERVRDARSKlKPDQPLLVHGITAVGRAGAFCALLN
|..|..| ...|| |... .. | |.|... . .| | .. | | . ..... .| | |.||.|... ... |.||| |||.|.|.|..
.gesltygdftvtllseehlddytvrtlevtnlgddesrevihyhylpwpdhgvpdllellldflefvrkalae.dsngpvlVHCsaGvgRtGtfiaayl
LLDRFDNERRLNVVDELTRLRQARSHFISDVVYLETILACVLDY
.|.... |..... . . .||. |.. . ... . ..|..
mleqlekelgvsleeavkelrsqRpgavqtpsqyrflyeallel
|
|||||||||
| 0037934 | (Phosphotyrosine protein) phosphatases II | 497-737 | 1.6e-35 | 118.2 | In-house | 3-240 (243) | alignment | ||
Range on Protein: 497-737
Range on HMM: 3-240/243.0
QTAMLPHNLEKNVRRNtLLPYEYNRVLLanPGekDQYYNASFIPTYsPQmpIIVAEGPQRPTLTL----FWQMMWQQEVSLVAMTTTISDGSQVVGERYW
.|.|| ||.|| .. |||...|| | .| . |.||..|. . |. .|. || |. ||.|.|.. .. . | |. . ... ..||
siallpenlsknrysd.ilpydhsrvkl..eg..sdyinanliyvt.pr..liatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqyw
PseGDIlEIGPLQITLEHEHTNLAICERSLRVKHID-LGITRDVKLLQMLFWVAGEACEDSHRFLAFAERVRDARSK------LKPDQPLLVHGITAVGR
| |.. ..|....|| .|.. .. | |.....| . || | .. | | . . .. .|.| . ||. .. |... |.||| |||
p..gev.tygdftvtllseehlddytvrtlllenldlddltrlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgR
AGAFCALLNLLDRFdnerRLNVVDELTRLRQARSH-FISDVVYLETILACVLD
.|...|.. .|... .... . . .||. |.. . ... . ..|
tGtliaaylmllll....gvdleeavkllreqRpgkavqtpsqyrflyealle
|
|||||||||
| subfamily_PTPRK_pd | Subfamily PTPRK | 497-725 | 5.5e-28 | 92.7 | In-house | 36-263 (314) | alignment | ||
Range on Protein: 497-725
Range on HMM: 36-263/314.0
QTAMLPHNLEKNvRRNTLLPYEYNRVLLAN-PGE-KDQYYNASFIPTYSPQMPIIVAEGPQRPTLTLFWQMMWQQEVSLVAMTTTISDGSQVVGERYWPS
..| .| ||| | . .|.|. || | |. . .| ||..| .| ||. || . |.. ||....... . . | | . . ..| .|||
daakkdenrekn.rsgdilaydrsrvflitidgdpssdyinaalidsykrpaafivtqgPlqetvkdfWrlvydencasivmltelvevgrvkClkyWPe
EGDIleIGPLQITLEHEHTNLAICERSLRVKHIDLG--ITRDVKLLQMLFWVAGEACEDSHRFLAFAERVRDARSKlkPDQPLLVHGITAVGRAGAFCAL
.... |.....| . ... . | .||... | .| |. .| | | . . . .|.. || . . . ...|| . ||.|.|.|.
dtev..ygdikvelvetellaelvvrifrveklargqeeirevrqfqflgWpdhdvPvsatgllklvrrvkksqee..eaGrivvhCsaGaGrtGtfiai
LNLLDRFDNERRLNVVDELTRLRQARSHFISDV
.|| ..|. ..| ||. .. ..
divldmieregvvdvfnavktlrsrkvnmvete
|
|||||||||
| subfamily_PTPN5_RR_pd | Subfamily PTPN5_RR | 497-736 | 1.7e-25 | 84.6 | In-house | 21-265 (274) | alignment | ||
Range on Protein: 497-736
Range on HMM: 21-265/274.0
QTAMLPHNLEKNvRRNTLLPYEYNRVLLANPGEKD---QYYNASFIPTYSPQMPIIVA-EGPQRPTLTLFWQMMWQQEVSLVAMTTTISDGSQVVGERYW
. ... . .|| | .|.|| | |||| . .| .| || .| |. . . || || |.. ||.|..|.||... |.| ... . ..|.
eeldvfgsqtkn.ryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntvadfWrmiyqeevqvivmltklkeaneqkCavyf
PSEGDI---LEIGPLQITLEHEHTNLAICERSLRVKHIDLgiTRDVKLLQMLFWVAGEACEDSHRFLAFAERVRDARSKLKPD-QPLLVHGITAVGRAGA
| . |. . | ..|. |. .. |.| .|. .|.|| | .. .| . .| . . |...|.. . | .|| .||.|.
Pdaedyeiserygdveikvekiverndysvrklvlkyler..ersvkhywytdWPdhksPddantlldlvleveesreeenaklapvvvhCsaGiGrtGc
FCALLNLLDRFDNERRLNVVDELTRLRQARSHFISDVVYLETILACVL
| | .. . ....| ..|. . ||. | . | | .
fiaisiavrqlreeivvdvlkivcnlrldrGGmvqtseqyelihralc
|
|||||||||
| subfamily_PTPN23_pd | Subfamily PTPN23 | 498-741 | 1.5e-39 | 130.6 | In-house | 37-282 (288) | alignment | ||
Range on Protein: 498-741
Range on HMM: 37-282/288.0
TAMLPHNLEKNvRRNTLLPYEYNRVLLAnpGEKDQYYNASFIPTYSPQMP-IIVAEGPQRPTLTLFWQMMWQQEVSLVAMTTTISDGSQVVGERYWPSE-
.|. . ||| | . .|||. ||| | |.|| | ||||. ||. | .|.. .|...|| ||.|...| .|.. | .. .. . .||||..
iaiaklysekn.rsrdilPyDhnRvklr..gskDDYinAsfvkdlspgcPdfiatqaPlqstlnDFWlmvyeqkssviVmllskeelgkpkvdrYwPedk
GDILEIGPLQITLEHEHTNLAICERSLRVKHIDLGITRDVKLLQMLFWVAGEACEDSHRFLAFAERVRD--ARSKLKPDQPLLVHGITAVGRAGAFCALL
|. . |.|..||..... || |.... | ...|..||. | . . . .|.| . |.. . | ..||.|| . |||.|.|. .
getvkfgdlsvtlksvretethvervlkletldadavksvshlqltsWpelGvPasPetllqfldevesayeavqrksktPlvvhCsaGvgRtgvfalvy
NLLDRFDNERRL-NVVDELTRLRQARSHFISDVVYLETILACVLDYAAN
. .... | .... . |||. | . .... |. . || .| .
aavrelekgnglldiiqvvsrlreqRrfmvqekeqlkfsyeavleaarr
|
|||||||||
| subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 498-740 | 1.4e-38 | 127.4 | In-house | 40-284 (290) | alignment | ||
Range on Protein: 498-740
Range on HMM: 40-284/290.0
TAMLPHNLEKNvRRNTLLPYEYNRVLLA-NPGEKD---QYYNASFIPTYSPQMPIIVAEGPQRPTLTLFWQMMWQQEVSLVAMTTTISDGSQVVGERYWP
... . | ..| | .....|. ||. | .|.|| .| ||..| |. . |...|| || ||...||..|. . | |.| . .|. |||
vgltssnklln.RfanivvyddnritLrpisghkDCtneyinAcyikgykekkqyiatqgpvsntlvdFWkliwqekvtiivmltniieegkvkCqqYWp
SEgDILEIGPLQITLEHEHTNLAICERSLRVKHIDL-GITRDVKLLQMLFWVAGEACED-SHRFLAFAERVRDARSKLkpDQPLLVHGITAVGRAGAFCA
.. | ..|. .|.| .|.| . || |.||. . | .. |. .|. | . ... . |...|... | . .....|| .|||.. |||
ds.dtkaygefsikllneetlneyierklevknknsagakqsvtqyqitnwdstgkvtnpqtillvieemyktqrkrg..ntsivvHCSdtvgrsavfca
LLNLLDRFDNERRLNVVDELTRLRQARSHFISDVVYLETILACVLDYAA
. . ... | .|.. | ..|. . . |. ...| || |
aattinkcktegvidvfqvlksqRiqkpgsvqtvqqyqgifqivltyld
|
|||||||||
| subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 498-736 | 3.1e-31 | 103.5 | In-house | 43-276 (315) | alignment | ||
Range on Protein: 498-736
Range on HMM: 43-276/315.0
TAMLPHNLEKNvRRNTLLPYEYNRVLL--ANPGEKDQYYNASFIPTYSPQMPIIVAEGPQRPTLTLFWQMMWQQEVSLVAMTTTISDGSQVVGERYWPSE
.| .| .|| | ..|. || | . .. .| ||.||. |. . | |.||. .. ||......... . | | . .| . |.||| .
vakkienkqkn.ryiniiaydksrvqlpllendphsdyvnanfidGynkkrryiaaqgpnvasvkdfwrlvfeedigkivmltnlvegekrkaekywpdk
gdILEIGPLQITLEHEHTNLAICERSLRVKHIDlgITRDVKLLQMLFWVAGEACEDSHRFLAFAERVRDARSKLKpdQPLLVHGITAVGRAGAFCALLNL
. |.. .|. | | .. |.| | | |.| |.. | . .. . .. . .|. . . ...|| |||.|.|..| .
..kviyGkitvtrkseevnteytvrtlsvvfgd..nirevvqlhytswpdmgvpkytiplmnlirtvkqhhtnsv..gaivvhcsaGvGrtGtfitldav
LDRFDNERRLNVVDELTRLRQARSHFISDVVYLETILACVL
||. . |. ..| . .|..|| | . .. . . | .|
ldqaeaenaidvynfitgvrqnrikmvqvaeqyqfiydall
|
|||||||||
| subfamily_PTPRN_pd | Subfamily PTPRN | 498-737 | 4.5e-29 | 96.1 | In-house | 50-290 (297) | alignment | ||
Range on Protein: 498-737
Range on HMM: 50-290/297.0
TAMLPHNLEKNvRRNTLLPYEYNRVLLANP--GEKDQYYNASFIPTYSPQMPIIV-AEGPQRPTLTLFWQMMWQQEVSLVAMTTTISDGSQVVGERYWPS
.| ..|..|| | ...|||. .|| | . ||..| |||.| |..|. . ..|| |.. ||||.|.| | .. . |.... . .||||
vakaeknvkkn.rskavlpydhsrvklkeeasaeksdyinasaildhdprapayiatqgplastvadfwqmvweqGvvvivnltrleeegvkqckrywpd
EGDI-LEIGPLQITLEHEHTNlAICERSLRVKHIDLGITRDVKLLQMLFWVAGEACEDSHRFLAFAERVRDARSKlkPDQPLLVHGITAVGRAGAFCALL
|| .| ... || .. ||. .| .. || | . | | . .. .. .| | .| . |..||. .||.|.....
eGsevyhiyevhlvsehiwcd.dylvrsfylknlqtsetrtvtqfhflswpeegvPasaksllefrrkvnksyrG..rscpivvhcsdGaGrtGvyilid
NLLDRFDN-ERRLNVVDELTRLRQARSHFISDVVYLETILACVLD
.|.|. . ...... | ||. |.... .| .|..| .
lvlnrllkGvkeidiaatlehlrdqrpglvktkdqfefaltavae
|
|||||||||
| 0049772 | (Phosphotyrosine protein) phosphatases II | 498-739 | 1.7e-16 | 56.3 | In-house | 40-280 (314) | alignment | ||
Range on Protein: 498-739
Range on HMM: 40-280/314.0
TAMLPHNLEKNVRRNTLlPYEyNRVLLAN-PGEKDQYYNASFIPTYspqMPIIVAEGPQRPTLTLF----------WQMM--WQQEVSLVAM--------
.| |. | .|| . | |.. ||| | . |.. |.|||.. .. . |...|| |. | |.|. ... | . |
vadlflnrdknryldil.pad.nrvilpglpvsgsdyinasyvdgf...lkfIatqgpleitvvdfreepvlyyngwrmvlrgdlnvrdivmsrdevlad
-------------TTTISDGSqvvgerywpS---EGDILEIGplqitlehehtnlaicerslRVKHIDLGITRD-VKLLQMlFWVAgEACEDSHRFLAFA
.... . . . |. .. .. . . .| .|.|.. . . . .. |..|
elsrLdaAlgKtpllildgng.........neptaadlellk....................eelydpelferlgikylri.pvpD.gsaplledfdefl
ERVRDArsklKPDQPLLVHGITAVGRAGAFCALLNLLDRFdnerRLNVVDELTRLRQARS-----HFISDVVYLETILACVLDYA
| ...| ... |.||| .||.| |... |. .. .... . | ..|..|. .|| .| || ..|.|
efieea....dkggpvlvHCkaGkgRtgtfvvaaylmkll....gvsleealedvrlkRpinpnpgfieqleqyefilealleyl
|
|||||||||
| subfamily_Sponge-PTP4_pd | Subfamily Sponge-PTP4 | 498-594 | 2.2e-07 | 24.8 | In-house | 90-180 (244) | alignment | ||
Range on Protein: 498-594
Range on HMM: 90-180/244.0
TAMLPHNLEKNvRRNTLLPYEYNRVLLANPGEKDQYYNASFIPTYSPQMPIIVAEGPQRPTLTLFWQMMWQQEVSLVAMTttisdGSQVVGERYWPS
|. | | || | . ||...||| |.. . | ||||. |... | | ||.|| .. | .. . || . |||
dafnpnnswkn.regaglpfdfnrvplskgsmgntyinasfvgclgrtaeyiltqhpladtsmdfwkmmlerhvnvlvvl.....gsveeedeywpd
|
|||||||||
| subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 499-741 | 6.2e-38 | 125.5 | In-house | 36-278 (281) | alignment | ||
Range on Protein: 499-741
Range on HMM: 36-278/281.0
AMLPHNLEKNVRRNtLLPYEYNRVLLANPG--EKDQYYNASFIPTYSPQMPIIVAEGPQRPTLTLFWQMMWQQEVSLVAMTTTISDGSQVVGERYWPSEG
. ..| .|| .| . |. || ... .. | ||.|.|.|. . |...|| .|. ||||.|.|.||...| | ..... |||| .
skadenvlknrYsn.ivaYDatrvkvtpneenkntDYinanfvpgykgekeyiatqgPvPaslvafWqmvweqkvsaivmvtreieagklkChrYWPddn
DILEIGPLQITLEHEHTNLAICERSLRVkHIDLGITRDVKLLQMLFWVAGEACEDSHRFLAFAERVRDARSKlKPDQPLLVHGITAVGRAGAFCALLNLL
|..| .... ..|... || ... . . | ||.|. |. . | . .... .| | . |. ...| | ..||..| . |||.|.. || |.
selkygdvtvkstaeeekatyierkfkl.eresgetreveqlaytaWPdhGvPattkellefrkevlkltek.ktkaplvihCsaGvGrtGtyialDrlv
DRFDNE-RRLNVVDELTRLRQARSHFISDVVYLETILACVLDYAAN
.. ..| ..|.| . .. ||..| .. || | . |||. .
kaveaeleeldvkavvaelrkernlmvqtvvqyefvykavldaldk
|
|||||||||
| subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 500-741 | 1.2e-32 | 108.2 | In-house | 46-286 (297) | alignment | ||
Range on Protein: 500-741
Range on HMM: 46-286/297.0
MLPH-NLEKNVRRNtLLPYEYNRVLLANPGEK--DQYYNASFIPTYSPqmPIIVAEGPQRPTLTLFWQMMWQQEVSLVAMTTTISDGSQvVGERYWPSEG
. |.||. .| |||. .|| || ... | ||||.... .| . |.. |. ||.|.....|| ..| . ... . |||. .|
aekkvnfeksRYkn.iLPydssRvkLaivnddpdsDyvnasfvkgnkh..rlittqmPmkatvadfWamvldeqvstivmlnddnerdk.kcaryWsdkg
dILEIGPLQITLEHEHTNLAICERSLRVKHIDLGITRDVKLLQMLFWVAGEACE--DSHRFLAFAERVRDARSKLKPDqPLLVHGITAVGRAGAFCALLN
. . | . ..|. . .|.| |.. . .| || | . | . . . . .| . . ||. |. . ||||| .. |||.| ......
.vttfGdvsvvllsvsereGfikrelevtkgkakarrvvkqyqfveWPdkaverkdsassllklisevrkdfsqnaeg.PllvhclaGvGrtgvlltids
LLDRFDNERRLNVVDELTRLRQARSHFISDVVYLETILACVLDYAAN
. . .| ... . ...||| | ... . . ||..
vvaeakrekevdifglvkklrqerpylvqtkeqykfvyvavlealls
|
|||||||||
| subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 500-602 | 5.2e-13 | 43.5 | In-house | 29-133 (297) | alignment | ||
Range on Protein: 500-602
Range on HMM: 29-133/297.0
MLPHNLEKNVRRNtLLPYEYNRVLLANPGEKDQYYNASFI--PTYSPQMPIIVAEGPQRPTLTLFWQMMWQQEVSLVAMTTTISDGSQVVGERYWPSE-G
. | || |. .| .. .|| | . . .| || .. | .. |.|.|| . |. ||.....|.| ..| . . .. . |||| .
krnsslrknryrd.ilatddtrvkllrviterdyinadyvvfpdeeadlkyilaqGplsatvddfwtlvaeqdvrvivmvaklqedGrdkcapywpsvvq
DILEIG
. |. |
erlkag
|
|||||||||
| subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 501-727 | 4.6e-30 | 99.6 | In-house | 6-230 (250) | alignment | ||
Range on Protein: 501-727
Range on HMM: 6-230/250.0
LPHNLEKNvRRNTLLPYEYNRVLLANPG--EKDQYYNASFIPTYSPQMPIIVAEGPQRPTLTLFWQMMWQQEVSLVAMTTTISDGSQVvGERYWPSEGDi
|.|.||| | ..... ||.| . .. | ||||. .|. . |.. || .|. ||.|....... . | |.... .. ..||| |.
kpqnkekn.ryadiialdssrvvLekekgdkesdyinasflhgyderkafiatqgPlqatiedfWrmvleeksgtivmLtnLkesekt.yhqywPveka.
LEIGPLQITLEHEHTNLAICERSLRVKHIDLGITRDVKLLQMLFWVAGEACEDSHRFLAFAERVRDARSKLKpDQPLLVHGITAVGRAGAFCALLNLLDR
. | ....| ... . | | . . | |. |. . | | . |.. ..|. . . . ..|..|. . |||.|||.|. .|.|
ekyGdvtvsllskeefadytkrklklskakkaderivrqlhfvvWPdkgvPevatavLellkkvqasqqqag.naPvivqCsaGvgrsGafiaidavler
FDNERRLNVVDELTRLRQARSHFISDVVY
.|. ..| . . .||. | | .
lkkekvvdvfkvikvlrkdrphavesleq
|
|||||||||
| subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 502-739 | 6.8e-35 | 115.4 | In-house | 45-278 (287) | alignment | ||
Range on Protein: 502-739
Range on HMM: 45-278/287.0
PHNLEKNvRRNTLLPYEYNRVLLAnpGEKDQYYNASFIPTYSPQMPIIVAEGPQRPTLTLFWQMMWQQEVSLVAMTTTISDGSQVVGERYWPSEGDiLEI
..| .|| | . .|... .|||| ||...| ||.|| .|. . |.||.| |. ||.......|. . | . . . | .|||.| . .
sqnkdkn.Rltqilvpdnyrvllk..gehpdyinavfidgykekkafiiaesPmfntarnfWkliddrnvtaivmlcqekendeevcyqyWpeeks.vvl
GPLQITLEHEHTNLAICERSLRVKHID-LGITRDVKLLQMLFWVA-GEACEDSHRFLAFAERVRDARSKlkPDQPLLVHGITAVGRAGAFCALLNLLDRF
|. .|.| .|..| || |.||. . | .. || |. | |. | .| . |... | . . ...|| .|||.. ||| ...
GeyniellneevnagyierklevknknkagdkqqvkqyqitnWdstgkvtepqtillvieemyktqrkr..gntsivvhCsdtvGrsamfcaaattinkc
DNERRLNVVDELTRLRQARSHFISDVVYLETILACVLDYA
..| ..|.. | . |. . . . | . | || |
kteGviDvfqvlksqriqkpgsvqtveqykfindivleyl
|
|||||||||
| subfamily_Ptp69D_pd | Subfamily Ptp69D | 502-741 | 2.3e-33 | 110.7 | In-house | 46-288 (307) | alignment | ||
Range on Protein: 502-741
Range on HMM: 46-288/307.0
PHNLEKNvRRNTLLPYEYNRVLLAN--PGEKDQYYNASFIPTYSPQMPIIVAEGPQRPTLTLFWQMMWQQEVSLVAMTTTISDGSQVVGERYWPSEgDIL
|. || | . . ... .|| |.. |. .| ||||| .| . |.| .| |. ||.|...||| |. | . ... .. ..||| | |.
kenalkn.RyedikafDktRvkLkkingkedsdYinasfikgykekkkfiaaqdPveatigDfWRmiaeqevtlivmlsnlteknrkkcakYWpie.dev
EIGPLQITLEHEHTNLAICERSLRVKHID-----LGITRDVKLLQMLFWVAGEACEDSHRFLAFAERVRDARSKLkpDQPLLVHGITAVGRAGAFCALLN
. | . ..| .|.. .|.| | ... . .| | . . | .. | .. | . |.||. .. |..|| . |||.| | ||
qygdilvklvseekhsdyiiReldvskkkeesgevedsrkvvqyhytgWkDskvPevargllklieqvrelykln..rsPivvhCsaGvgrsgifvalds
LLDRFDNERRLNVVDELTRLRQARSHFISDVVYLETILACVLDYAAN
||.. .| ...... ||. |. .. . . .|||
llqqlkaedkvdifetvkdLrsqRnllvqsleqYvflyralldyssy
|
|||||||||
| subfamily_CG7180_pd | Subfamily CG7180 | 502-725 | 8.7e-31 | 101.6 | In-house | 40-276 (296) | alignment | ||
Range on Protein: 502-725
Range on HMM: 40-276/296.0
PHNLEKNvRRNTLLPYEYNRVLLAN-PG-EKDQYYNASFIPTYSPQMPIIVAEGPQRPTLTLFWQMMWQQEVSLVAMTTTISDGSQvVGERYWPSEGdIL
.|.||| | . .||.||||.| . | ||..| ||... .. . || |.|.. |. ||......|.| | . | | .. ||| ..
kenrekn.rdvkvvPyDynRvvLekldGeeksdYinavyvdsflkkkeyivteapkketvdefWrlvydeeisavvvLtktfdfak.mypsywpnks.ke
EIGPLQITLEHEHTNLAICERSLRVKHI-------DLG---ITRDVKLLQMLFWVAGEACEDS-HRFLAFAERVRDARSKL---KPDQPLLVHGITAVGR
. |.. . . .|.. .. | ..... . . || |||.|. | .. . | .. . .||| | | . .|..|. ..|
qygeifveiveekqyanlkirtfkltkkivalteqekqvkaetRivklfqlteWeledkvPlstnalielrrrvrlwrekvdedpeegPvvvvssdGasR
AGAFCALLNLLDRFDNERRLNVVDELTRLRQARSHFISDV
.|...|. |. ..| ...| . . .||. | . . |
sGvylaidanlelvekeeevdvFeavktlrrsRpqLvenv
|
|||||||||
| subfamily_PTPN13_pd | Subfamily PTPN13 | 503-722 | 1.3e-28 | 95.0 | In-house | 36-252 (273) | alignment | ||
Range on Protein: 503-722
Range on HMM: 36-252/273.0
HNLEKNVRRNtLLPYEYNRVLLANPGEkdqYYNASFIP--TYSPQMPIIVAEGPQRPTLTLFWQMMWQQEVSLVAMTTTISDGSQVVGERYWPSE-GDIL
.| .|| || .|||. || | . | | |||.| . |.. || | . ||||.|.|.....|| |. .. .| .||||.. .. |
enkdknryrn.vlPydetrvklgdegg...yinaslikvpvgkdeyeyiacqGPlPetvkdfwqmvweqkaeviamvtlekekgkvkchrywPesknkkl
EIGP-LQITLEHEHTNLAICERSLRVKHIDLGITRDVKLLQMLFWVAGEACEDSHRFLAFAERVRDARSklkPDQPLLVHGITAVGRAGAFCALLNLLDR
. |...|.. . |.| ||... | .|.| |.. | . . .| |. .|| .. |..|| . .||.|.. .. .|.
kvsnrlevellkvqkldgfvvralavkdsesgesrevahlnfvkwPdhgvPssaaellqfvaevrrlqt...dagPivvhcsaGiGrsGtlitidvvlgl
FDNERRLNVVDELTRLRQARSHFI
.... ..| . . .||. | .
ierdkefdvkeivrklreqrqgvv
|
|||||||||
| subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 503-723 | 1.1e-27 | 91.4 | In-house | 42-260 (515) | alignment | ||
Range on Protein: 503-723
Range on HMM: 42-260/515.0
HNLEKNVRRNtLLPYEYNRVLL--ANPGEKDQYYNASFIPTYSPQMPIIVAEGPQRPTLTLFWQMMWQQEVSLVAMTTTISDGSQVVGERYWPS-EGDIL
| .|| .| |||. .|| | | . |.|||.||.. . | . ||.. .. ||....|..|. .|| | ..| .. .||| || .
infkknrykn.ilPydsvrvklevindnPhsdyfnasyipsfdndkayiasqgPnkasvddfWrlvlqenvttiamvtklkegdkikcgkyWPdkpgdsv
EIGPLQITLEHEHTNLAICERSLRVKHIDLgiTRDVKLLQMLFWVAGEACEDSHRFLAFAERVRDARSKLKpdQPLLVHGITAVGRAGAFCALLNLLDRF
. | ... | .. | |.| . | .| | .. | . ... .| . |. ..... ||..| . |||.| .... . . .
kfGsikvelvsleactggikrkltvlkgdd..srtvtqfhfteWPdkGvpkhtssllklikevkadhgqyt..hpliihcsaGvGrtGvvisidsvvaha
DNERRLNVVDELTRLRQARSHFIS
. | ..| . .| .|| | ...
kttrmvdvfnfvtnirqkrpylvq
|
|||||||||
| subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 503-722 | 4.5e-16 | 53.7 | In-house | 31-242 (267) | alignment | ||
Range on Protein: 503-722
Range on HMM: 31-242/267.0
HNLEKNVRRNTLLPYEYNRVLLANPGEKdqYYNASFIPTYSPQMPIIVAEGPQRPTLTLFWQMMWQQEVSLVAMTTTISDGSqvVgERYWPSE-GDILEI
.. .. | . |||. .|| | . | | |||.. .| . || ..| . | | |.... .|.|. . . |.. . . ..|| . |. .
eknqernrlddnlpyddtrvilrtkeee..yinasyvegyktknafivtqdplkntitdfltvihdqkvpvivlltkvftdn..i.rlfwPPkmgqakky
GPLQI--TLEHEHTNLAICERSLRVKHIDlgiTRDVKLLQMLFWVAGEaceDSHRFLAFAERVRDARSKLKPDQPLLVHGITAVGRAGAFCALLNLLDRF
| . .||.| . | |..| ...| | | . . .| . . ..||.|. |||.|.| . |.|
qdltvehslekeendyqiitlelkfknes...ahnvtlyyykkwnint...nnkpylkplfgilaknqlengnrPlvvacsdGvGrsGtflvidsqlera
DNERRLNVVDELTRLRQARSHFI
.| ... | | ..|. | ..
ktegvsdifdflrkirsqriglv
|
|||||||||
| subfamily_ptpA1_pd | Subfamily ptpA1 | 503-701 | 1.3e-12 | 42.2 | In-house | 46-258 (418) | alignment | ||
Range on Protein: 503-701
Range on HMM: 46-258/418.0
HNLEKNvRRNTLLPYEYNRVLLANPGEK--DQYYNASFIPTYSPQMpIIVAEGPQRPTLTLFWQMMWQQEVSLVAMTTTISDGSQVVGERYWPSE--GDI
|| || | .|| .. || | . .| .| || .| |. .|...|| |.. ||.|.|.. . .. | . |. .. .|||| . |.
hntskn.rytnilpvnhtrvqlkkiqdkegsdyinanyidgaypkq.fictqgplpntiadfwrmvwenrcriivmlsresencrikcdrywpeqiggeq
LEIG-P---LQITLEHEHTN-LAICERSLRVKHIDL---GITRDVKLLQMLFWVAGEACEDSHRFLAFAERVRDARSKLKPD----QPLLVHGITAVGRA
. | . | | . . || . . | | | |||. | | . . .. | . . . . .. | |..|| . |||.
fsiygngnevfgtysvelveviqdpereiitrnirltfegetrditqyqyegwpdhnipdhtqpfrqllhsitnrqnqiipssdrnvpiivhcsagvgrt
GAFCALLNLLDRFDN
|.||. . .. ..|
gtfctavimmkkldh
|
|||||||||
| subfamily_Cele-PTP-6_pd | Subfamily Cele-PTP-6 | 503-725 | 2.4e-12 | 41.5 | In-house | 40-263 (307) | alignment | ||
Range on Protein: 503-725
Range on HMM: 40-263/307.0
HNLEKNvRRNTLLPYEYNRVLLANPGEKDQYYNASFIPTYSPQMPIIVAEGPQRPTLTLFWQMMWQQEVSLVAMTTTISDGSQVVGERYWPSE-GDILEI
| .|| | . . . .|... .| .| | .. . .|.|.||. | || |. |..| | | . . ... |.||| | |. |
antdkn.ryqdvkcqdkgrivvkfdglasdyihanylgiaikpkkficaqgplentqysfwamaiqekvesvimlckvielakikceqywpleegqklvf
G--PLQITLEH-EHTNLAICERSLRVKHIDLGITRDVKLLQMLFWVAGEACEDSHRFLAFAERVRDARSKlkpDQPLLVHGITAVGRAGAFCALLNLLDR
| | |... .|| | . | ... ... . .| | | . |. . . | . |..|| . |||.|. |. . |.
geapntisvanlgakklapdedlinvttlkvdwaqksrtiqhlqwenwpdrgvpqinltainlleavryd...tnpvvvhcsaGvGrsGtivaislvqdk
FDNERRLNVVDELT-RLRQARSHFISDV
. ...| ||. | . | .
miaGinckdmkklveelrsqrhyaiqte
|
|||||||||
| subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 505-720 | 2.8e-20 | 67.5 | In-house | 4-220 (237) | alignment | ||
Range on Protein: 505-720
Range on HMM: 4-220/237.0
LEKNvRRNTLLPYEYNRVLLANPGEKDQYYNASFIPTYSPQ-MPIIVAEGPQRPTLTLFWQMMWQQEVSLVAMTTTISDGSQVVGERYWPSEGDILEIGP
|| | . |...||.| .| . .| ||... . | |.|| .. ||||.||. |.. | | . .| .. .|||| . |
kikn.rygnivaydhsrvvlkgagsgsdyinatylkgfdgtpkkyiaaqgplesscddfwqmvwqekcsvivmltgliegnelkchkywpstdqpaaygv
LQITLEHEHTNLAICERSLRV-KHIDLGITRDVKLLQMLFWVAGEACEDSHRFLAFAERVRDARSKLKPDQPLLVHGITAVGRAGAFCALLNLLDRFDNE
| ..| .. ||| . |.. | | .. |. | . . .| | .. . .. | ..| ..|||.| | . .| . ..
ltvslkkkeefsdytvrslllskrltlkevrlihqyqftswpdrgvpqqtaallrfrkniinrsphvsesgpwiihcsagvgrtgiflvidamlrqakek
RRLNVVDELTRLRQARSH
. ... . . . . | .
kvvdiynyvysieedrpy
|
|||||||||
| Y_phosphatase | Protein-tyrosine phosphatase | 506-736 | 6.5e-43 | 142.2 | Pfam-A | 3-234 (235) | alignment | ||
Range on Protein: 506-736
Range on HMM: 3-234/235.0
EKNvRRNTLLPYEYNRVLLANPGEKDQYYNASFIPTYSPQMPIIVAEGPQRPTLTLFWQMMWQQEVSLVAMTTTISDGSQVVGERYWP-SEGDILEIGPL
.|| | .. |||. .|| | . ... .|.||... .|. . .|...|| |. ||.|.||..|....| |. . ... ..||| .|.. |. | .
kkn.RykdilpydktrvklkgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeesltygdi
QITLE-HEH-TNLAICERSLRVKHIDLGI-TRDVKLLQMLFWVAGEACEDSHRFLAFAERVRDARskLKPDQPLLVHGITAVGRAGAFCALLNLLDRFDN
...|. .|. . ... | |..|. . .| || |.. | .. |... .| . ..|. . . ..|..|| .. |||.| |.|| ||.....
kvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkveksk..eaksgpvvVhCsaGvgRtgtfvaldilleqlea
ERRLNVVDELTRLRQARSHFISDVVYLETILACVL
|. ..|.. . .||. | . .... .. . ...|
eeevdvlqivkelRkqRpgmvqsleqYiflykail
|
|||||||||
| Y_phosphatase | Protein-tyrosine phosphatase | 506-736 | 6.5e-43 | 142.2 | In-house | 3-234 (235) | alignment | ||
Range on Protein: 506-736
Range on HMM: 3-234/235.0
EKNvRRNTLLPYEYNRVLLANPGEKDQYYNASFIPTYSPQMPIIVAEGPQRPTLTLFWQMMWQQEVSLVAMTTTISDGSQVVGERYWP-SEGDILEIGPL
.|| | .. |||. .|| | . ... .|.||... .|. . .|...|| |. ||.|.||..|....| |. . ... ..||| .|.. |. | .
kkn.RykdilpydktrvklkgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeesltygdi
QITLE-HEH-TNLAICERSLRVKHIDLGI-TRDVKLLQMLFWVAGEACEDSHRFLAFAERVRDARskLKPDQPLLVHGITAVGRAGAFCALLNLLDRFDN
...|. .|. . ... | |..|. . .| || |.. | .. |... .| . ..|. . . ..|..|| .. |||.| |.|| ||.....
kvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkveksk..eaksgpvvVhCsaGvgRtgtfvaldilleqlea
ERRLNVVDELTRLRQARSHFISDVVYLETILACVL
|. ..|.. . .||. | . .... .. . ...|
eeevdvlqivkelRkqRpgmvqsleqYiflykail
|
|||||||||
| subfamily_Sponge-PTP5_pd | Subfamily Sponge-PTP5 | 506-737 | 9.9e-26 | 85.3 | In-house | 34-264 (283) | alignment | ||
Range on Protein: 506-737
Range on HMM: 34-264/283.0
EKNVRRNTLLPYEYNRVLLANpgEKDQYYNASFIP---TYSPQMPIIVAEGPQRPTLTLFWQMMWQQEVSLVAMTTTISDGSQVVGERYWPSEGDIlEIG
.. | . ..|.. .|| | . | .| ||.||| | . |.| .| . | ||.|....... . | | . .. .. .|||..| . . |
krknrnqeivpadqwrvelks..esrdyinavfipvsksykqdkkyiiaqsPldrtvvdfWkmvfdekitaivmltklqedlrikCsqyWPkrGse.dyG
PLQITLEHEHTNLAICERSLRVKHI-DLGITRDVKLLQMLFWVAGEACEDSHRFLAFaERVRDARSKlKPDQPLLVHGITAVGRAGAFCALLNLLDRFDN
.. .||..| |. . . | ... | . |. |. . .. | ..|. . . ... |..|| |..||...|.|. ..
eftvtlrkettsnsfiikelllrvnssakstlllahyqvidWleygeqaiinslvkf.nkvislqte.skkgPivvhCstgiGrtavfiaasasvkdalt
ERRLNVVDELTRLRQARSHFISDVVYLETILACVLD
| ..| .. .|. | . . ||.
esvvdvfavvkimreqrmmavqtldqyklvhelvle
|
|||||||||
| subfamily_eak_pd | Subfamily eak | 507-626 | 1.1e-06 | 22.3 | In-house | 51-174 (332) | alignment | ||
Range on Protein: 507-626
Range on HMM: 51-174/332.0
KNVRRN--TLLPYEYNRVLLANP-GEKDQYYNASFIPTYSPQMPIIVAEGPQRPTLTLFWQMMWQQEVS-LVAMTTTISDGSQvVGERYWPSEG-DILEI
..|.|| ..||... | |.. ... | ||| . |.. .. . .||||. .| .| . . . . ..|.| .. . |.
eavnrnvvkivpydrylvrltssqlnrlGyinaslaefsevGrkyiltGiasedkvfafwqmvleqkspaivqlledvelkle.ksdkyfpdktreelkf
GPLQITLEHEHTNLAICERSLRVKH
| |... . . . | | ..
Gildverkefvkrniletrllelsk
|
|||||||||
| subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 509-724 | 2.4e-31 | 104.0 | In-house | 50-268 (305) | alignment | ||
Range on Protein: 509-724
Range on HMM: 50-268/305.0
VRRNTLLPYEYNRVLLANPGEKD--QYYNASFIPTYSPQMPIIVAEGPQRPTLTLFWQMMWQQEVSLVAMTTTISDGSQVVGERYWPSE-GDILEIGPLQ
| . ... .|. |.. ..| .| |||.. .|. . ||| || . |.. ||..... || . | | . .| . ..||| . .. |.|...
nrlkeitlldddriiltekeslddsdyinasyvdgykrkkkyivaqgPlkntvadfWrliveekvstivmltklveggkdkCrqYWpesktekkefgefs
ITLEHEHTNLAICERSLRVKHID-LGITRDVKLLQMLFWVAGEACEDSHRFLAFAERVRDARSKLKpDQPLLVHGITAVGRAGAFCALLNLLDRFDNERR
..|. |.| || |.. | .| | .|. | . . .| . .||. ...| | ..||||| .|||.|.|.|. |.| .|
velksektasdyieRklkisiededkesrtvlqyqltdWPdhGvpqfatsllslikrvqkdqkkdk.gvpllVhCsagvgRtGvfiavdialerlkkEev
LNVVDELTRLRQARSHFISD
..| . | .||. | ..
vdvfevlkqlRskrmkmvqt
|
|||||||||
| subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 509-742 | 1.3e-26 | 88.2 | In-house | 24-267 (270) | alignment | ||
Range on Protein: 509-742
Range on HMM: 24-267/270.0
VRRNTLLPYEYNRVLLANPGE--KDQYYNASFIPTYS-PQMPIIVAEGPQRPTLTLFWQMMWQQEVSLVAMTTTISDGSQVVGERYWPSEGDI---LEIG
| . .|| || |.. | . .|.|| ... .. . | | ||. ||. ||.|.|...|. ..||| . . . |||||.| . || |
nRyadiLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpaepkekvkledg
PLQITLEHEHTNLAICERSLRVKhiDLGITRDVKLLQMLFWVAGEA------CEDSHRFLAFAERVRDARSKLKPDQPLLVHGITAVGRAGAFCALLNLL
.... ..|. . . ||.. . | .| . .. | . ... |. . || ...|. .||||| |||.| . || .
kikvlalseekeegyiltrlrle..ekgeerrlvHfwyntWpdhgvpreedsslstdqllkmlravrrsekeldkaePllvHcsaGvgRtGtlialDiav
DRFDNERRLNVVDELTRLRQARSHFISDVVYLETILACVLDYAANK
.......|. ...||. | ... .. | . . |. || .
rlLeetkkvdvlaiieelRkdRmalvqhpeqyeflykavveyaerr
|
|||||||||
| 0041856 | (Phosphotyrosine protein) phosphatases II | 510-723 | 6.2e-18 | 60.5 | In-house | 6-155 (182) | alignment | ||
Range on Protein: 510-723
Range on HMM: 6-155/182.0
RRNTLLPYEYNRvllanpgeKDQYYNASFIPTYSPQMPIIVAEGPQRPTLTLFWQMMWQQEVSLVAMTTtisdgsqvvGERYWPSEGdileigplqitle
| |||...| | ||... . |.. .|.. || |. |..|.... .... . | .|.|||..
rysdilpydhsr........dldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlt.........eelywpell.............
hehtnlaicerslrvkhidlgiTRDVKLLQMLFWVAGEACEdSHRFLAFAERVRDarsklkPDQPLLVHGITAVGRAGAFCALLNLLDRfdnerRLNVVD
.| . .. |.| ..... . .|.| |.|.. .. | ||| |||.|...|. .. . .... .
......................erlgiqylylpwpDhgvpd.ldelldfieevle......eggpvlVHCsaGvgRtgtlvaaylmkkl.....gvslee
ELTRLRQARSHFIS
. .|..|.. .
avklvrsrRpgmvi
|
|||||||||
| subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 510-724 | 4.3e-14 | 47.3 | In-house | 13-226 (239) | alignment | ||
Range on Protein: 510-724
Range on HMM: 13-226/239.0
RRNTLLPYEYNRVLLANPG--EKDQYYNASFIPTYSPQM-PIIVAEGPQRPTLTLFWQMMWQQEVSLVAMTTTISDGSQVVGERYWPSEGDilEIGPLQI
| .. |...||.| . . .| |||.. | | ..| .. ||.||||. .. | | . .| . .||| . |..
ryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpdsts..kycnlrv
TLEHEHTNLAICERSLRVKHIdlGITRDVKLLQMLFWVAGEACEDSHRFLAFAERVRDARSKLKPDQPLLVHGITAVGRAGAFCALLNLLDRFDNERRLN
|| . |.. . .. | | . . | | | . . . | . .. | .| ..| . |||.||| . .| . ... ..
tlrktevfadyiirtfvmsqv..gqteeryvyqyhftvwpdkgvpqyatavlglrrkitkdslpgarpwvihcsagvgrtgaflvidamlrqakkqktvd
VVDELTRLRQARSHFISD
... . .|. | |..
ifnyvkairedrphmvqt
|
|||||||||
| subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 510-724 | 4.4e-14 | 47.2 | In-house | 12-225 (239) | alignment | ||
Range on Protein: 510-724
Range on HMM: 12-225/239.0
RRNTLLPYEYNRVLLANPG--EKDQYYNASFIPTYSPQM-PIIVAEGPQRPTLTLFWQMMWQQEVSLVAMTTTISDGSQVVGERYWPSEGDilEIGPLQI
| .. |...||.| . . .| |||.. | | ..| .. ||.||||. .. | | . .| . .||| . |..
ryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpdsts..kycnlrv
TLEHEHTNLAICERSLRVKHIdlGITRDVKLLQMLFWVAGEACEDSHRFLAFAERVRDARSKLKPDQPLLVHGITAVGRAGAFCALLNLLDRFDNERRLN
|| . |.. . .. | | . . | | | . . . | . .. | .| ..| . |||.||| . .| . ... ..
tlrktevfadyiirtfvmsqv..gqteeryvyqyhftvwpdkgvpqyatavlglrrkitkdslpgarpwvihcsagvgrtgaflvidamlrqakkqktvd
VVDELTRLRQARSHFISD
... . .|. | |..
ifnyvkairedrphmvqt
|
|||||||||
| subfamily_Sponge-PTP9_pd | Subfamily Sponge-PTP9 | 512-718 | 2.9e-17 | 57.3 | In-house | 47-272 (301) | alignment | ||
Range on Protein: 512-718
Range on HMM: 47-272/301.0
NTLLPYEYNRVLLANPGE----KDQYYNASFIPTYSPQMPIIVAEGPQRPTLTLFWQMMWQQEVSLVAMTTTISDGSQVVGERYWPS-EGDILEIGPLQI
. .|. ||..|.. . . .| |||.| || . |.|.|| . ||. ||...||. .. . | | .|.. |.|||. | . | ||...
knitvyddnriilkpkpnldlcqreyinasyidgysekkkfiaaqgpmkktlvdfWrliwqekpvsivmvtnlkegtkskceqywpnseaeseefgpftv
TLEHEHTNLAIC-----------------ERSLRVKHIDlgITRDVKLLQMLFWVAGEACEDSHRFLAFAERVRDARSKLKpDQPLLVHGITAVGRAGAF
|| .|.. ||...||. ..|| ||. | . . | . | .. | |..|| .|.|.| .
tlvneqvyPdfvirqlnvkiqdgsnngyierkfkvksdk..sswdvlqlqvtdWpqdGvvreprtvLqviddvihrqqkig.ggpvvVHCSdtVsrsGvY
CALLNLLDRFDNERRLNVVDELTRLRQAR
|.. |. | .|.. ..|. .
csvsiglEQckaegVVdvfqvtkavrrsk
|
|||||||||
| subfamily_Cele-PTP-16_pd | Subfamily Cele-PTP-16 | 514-729 | 1.3e-07 | 25.6 | In-house | 56-269 (303) | alignment | ||
Range on Protein: 514-729
Range on HMM: 56-269/303.0
LLPYEYNRVLLANpgekDQYYNASFIPTYSpQMPIIVAEGPQRPTLTLFWQMMWQQEVSLVAMTTTISDGSQVVGERYWPSEGDILEIGPLQITLEhEHT
.. .. .| |.. | ||.. | . |... | | . ||||. .| | | . | |. .. |. .| . |.|.. | . |
vicldhskvklsd....ssyihasylelds.skkailtqlplshtaadfwqmiieqkvkcvlllltdseydklggdsvfprnqdflkfeersirvg.efk
NLAICE-RSLRVKHIDLGITRD-VKLLQMLFWVAGEACED-SHRFLAFAERVRDARSKLKPDQPLLVHGITAVGRAGAFCALLN-LLDRFDNERRLNVVD
.. . . .|.| . | . ... . | .. | | .|. ... | . .| . .. .||||.|. . | ... |..|
rvelgdgwvlkvlsvsngdyksflhvhhykawphnsipsdgspkfvkqiwqlqsvlrkysdstptvymslsgcgragtfalfetahlslhseqasldlvk
ELTRLRQARSHFISDVVYLE
| .|. | | . .. .
clenvrngrlhavqnlsqfs
|
|||||||||
| subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 515-740 | 1.1e-15 | 52.0 | In-house | 66-284 (290) | alignment | ||
Range on Protein: 515-740
Range on HMM: 66-284/290.0
LPYEYNRVLLANpGEKDQYYNASFIPTYSPqmPIIVAEGPQRPTLTLFWQMMWQQEVSLVAMTTTISDGSQVVGERYWP-SEGDILEIGPLQITLEHEHT
. ||.| . | . .| | .. . ..|...|. . | .|.|. |..|. . | . . . |.|.| ||..| .| . .. |..
vcndktrvilkd.GydGdyvhanyvkGlka..mfiltqGalkdtvidiwrmvlqekvaaivmlceliedGkakceqyypekeGevltfGeitvlcseedd
N-LAICERSLRVKHIDLGITRDVKLLQMLFWVAGEACEDShrfLAFAERVRDARsklKPDQPLLVHGITAVGRAGAFCALLNLLDRFDNERRLNVVDELT
. | . | |.. | | .| |.. | . ||. .| | | |. || . .||.|.| |. |. . . . |...|
kdaniikktlsvrdkdsGkehklkhlkikswpdksvalst...lallrtlrilr...kasGpvvvhcsaGiGrtGtfvaievglqilldGkeldlldlvr
RLRQARSHFIS-DVVYLEtILACVLDYAA
||..| . |. || .. .||.
alrnsrlnsvqvdiqyla.lveilldlGk
|
|||||||||
| subfamily_Cele-PTP-10_pd | Subfamily Cele-PTP-10 | 517-744 | 1.7e-08 | 28.5 | In-house | 67-294 (305) | alignment | ||
Range on Protein: 517-744
Range on HMM: 67-294/305.0
YEYNRVLLANPGeKDQYYNASFIPT-YSPQMPIIVAEGPQRPTLTLFWQMMWQQEVSLVAMTTTISDGSQVVGERYWPS-EGDILEIGPLQITLEHEHTN
. . |.|..| .| | .. |. .|.|.|| |. || |. |. | . | . .. .||| |. ||. . . ..
qdqsavkldkps.psdyihanyvgcpmipekrficaqgpldqtidefwwmviqnkveqivmlcktvelgklkcaqywpaaqgeklelksgivvenvsgsk
LAICERSLRVKHIDLGITRDVKL-LQMLFWVAGEACEDSHRFLAFAERVRDARSKLkpdQPLLVHGITAVGRAGAFCALLNLLDRFDNERRLNVVDELT-
. ... ..| . | |. .. | | |. | . | |..|| . .||.|. |. .|.. .... . ||
pmerdaeiqitllnltysgdqkmsvrhlqwtewpdrgvppckltslellsairgsk...vpivvhcsagigrtgtivaieyilekiaenkpcppmpelvk
RLRQARSHFIS-DVVYLeTILACVLDYAANKDK
||. |.. | || || | .|.| .| |
alrdqrafsiqndvqyl.fihrvmlnyflekyk
|
|||||||||
| subfamily_Cele-PTP-4_pd | Subfamily Cele-PTP-4 | 517-742 | 1e-07 | 25.7 | In-house | 63-288 (302) | alignment | ||
Range on Protein: 517-742
Range on HMM: 63-288/302.0
YEYNRVllANPGEKDQYYNASFIPTYSPQMPIIVAEGPQRPTL---TLFWQMMWQQEVSLVAMTTTISDGSQvVGERYWP-SEGDILEIGPLQITLEH-E
.. |.| ...|.|.|.||| . . . .||.| |.. . ||.|..|... | . . .. . ..| || .| | . . |
ldsnlv..kleaepdsyvnaskvevPeltrsiilaQlpkvdsedsveeFWrmvfqekivsvvilvgeeelkk.tlselfpkksgdykeygkmfvNnrkVe
HTNLAICERSLRVKHIDLGITRDVKLLQMLFWVAGEACEDSHRFLAFAERVrdARSKLKPDQPLLVHGITAVGRAGAFCALLNLLDRFDNERRLNVVDEL
... . . .. | . . ... . .| . . . . . |. | .| | |..... .|||||| .| ... ... |. . .
kaeeektryviEvlPegcsnsvlanvyvltnWkqkkvpvkyaeliktaakv..fakkikadentvivSknGaGRagafltlavaveklqkgkepnikeiv
TRLRQARSHFISDVVYLETILACVLDYAANK
. .|. |.. . . .. ..| | .|
ksiRsqRpravdslkQyvslyialllyikkk
|
|||||||||
| subfamily_Cele-PTP-15_pd | Subfamily Cele-PTP-15 | 518-721 | 1.3e-10 | 35.8 | In-house | 48-252 (285) | alignment | ||
Range on Protein: 518-721
Range on HMM: 48-252/285.0
EYNRVLLANpgEKDQYYNASFIPTY-SPQMPIIVAEGPQRPTLTLFWQMMWQQEVSLVAMTTTISDGSQVVGERYWPSE-GDILEIGPLQITLEH--EHT
| ||.| | .| ||.. | | ..|| ||. ||.|..|.... | | |. .| |.| . |.....| .||| | .
eetrvvlkn..hdrdyihaswmrmpgkdqstyittqgplpetlsdfwhmiyqekiayvlmlctlfeggvekcalyypeklgevvkfgkyeitlteckeea
NLAICERSLRVKHIDLGITRDV--KLLQMLFWVAGEACEDSHRFLAFAERVRDARSKlkpDQPLLVHGITAVGRAGAFCALLNLLDRFDNERRLNVVDEL
.| | . . . . .|. .| | ||.. .. . . |. | ..|. || . |||. .| . | .. ....| .
iagtilnaltvintedasseplymnhvqvpwwpdqlapedarpmielykwvkkvnpk...ekpicvhcsagvgrtatfvgidyatirimenpniemldiv
TRLRQARSHF
.| | .
remramrfqa
|
|||||||||
| subfamily_Cele-PTP-8_pd | Subfamily Cele-PTP-8 | 519-739 | 1e-09 | 32.9 | In-house | 57-271 (288) | alignment | ||
Range on Protein: 519-739
Range on HMM: 57-271/288.0
YNRVLLAnpGEKDQYYNASFIPTYSPQMPIIVAEGPQRPTLTLFWQMMWQQEVSLVAMTTTISDGSQVVGERYWPSE-GDILEIGPLQITLEHEHTNLAI
. || | . | | .| ... . .| |. | . |. .|.|. ...| . | . . . . . |.||. |. || | ......
itrvkls..ddpdfyiaanvvssakykrrlicaqaPlngtieelWkmllesdveyivmlcellekGkeksaeyfPsklGekarigrlctvvkkkradidk
CERSLRVKHIDLGITRD-VKLLQMLFWVAGEACEDSHRFLAFAERVrdaRSKlkpDQPLLVHGITAVGRAGAFCALLNLLDRFDNERRLNVVDELTRLRQ
. .. | .. || | .| | |. .| . |.. .| ..|..|| . |||.|.. | |. . | . |..||.
lvkvsllriskegeekvivkilhlleWdddgvPenylsplrllevl...ksl...qkPivvhssaGvGrtgtlililialeslrlddflgirsllaklre
ARSHFISDVVYLETILACVLDYA
| . | . |||..
erfkaiqtemqylyvhrcvleel
|
|||||||||
| subfamily_CG42327_pd | Subfamily CG42327 | 519-657 | 3.1e-08 | 27.6 | In-house | 42-185 (319) | alignment | ||
Range on Protein: 519-657
Range on HMM: 42-185/319.0
YNRVLLANPG--EKDQYYNASFIPTYS-PQMPIIVAEGPQRPTLTLFWQMMWQQEVSLVAMTTTISDGSQVVGERYWPSEG---DILEIGPLQITLEHEH
|| | . | .||.| .||.. | . | |. . . . ||...|.| . | .|. | .|.|.. . | ...|| .
etrvvlqrigdddkdeyldasyvrGyddapnsyiaaqvsledsssdfwrtvweqqsrvivqltdlselGikvcaeylPtketldntslyGdilvtlkgre
TNLAICERSLRVKHIDLGITRDVKLLQMlFWVAGEACEDSHRFLA
.. .| .|..| .|.. |. | . ..|
vkdryaistlllkrvdkeesrelthywy.kwleaevPaeeaalia
|
|||||||||
| subfamily_Cele-PTP-11_pd | Subfamily Cele-PTP-11 | 521-742 | 2.4e-06 | 21.5 | In-house | 59-279 (312) | alignment | ||
Range on Protein: 521-742
Range on HMM: 59-279/312.0
RVLLAnpGEKDQYYNASFIPTYSPQMPIIVAEGPQRPTLTLFWQMMWQQ-EVSLVAMTTTISDGSQVVGeRYWPSEGDILEIGPLQITLEHeHTNLAICE
| || |... | | |. . .....|| | | |||. .|.. ... . |||. . .| .... .. |. |.. |
rftla..gdenfyihanfvkictkperfvctqgplentcthfwqlalslgstsiillcgfvedgsekca.kyisdivgfvdledhrvytey.cteieigg
RS--------LRVKHIDLGITRDVKLLQMLFWVA---GEACEDSHRFLAfaervrdARSklKPDQPLLVHGITAVGRAGAFCALLNLLDRFDNERRLNVV
.| |.| | .. | | ..|. ..|.|. | | .|.. | . |||.|... . .. . |. ||
kskdkithrvlkvvvkatgqesklnhyqwaswpdhgmpdscdtalrlls.......avk..kdkkpviahcsagvgrtgtlaliesmiaalrhprkqnvk
DELTRLRQARSHFISDVVYLETILACVLDYAANK
| . ||. |. . . | |||.. .|
dsfvllrkdrarsvrvfpqyvyalrcvleflysk
|
|||||||||
| 0043147 | (Phosphotyrosine protein) phosphatases II | 529-727 | 2.4e-17 | 58.7 | In-house | 3-149 (172) | alignment | ||
Range on Protein: 529-727
Range on HMM: 3-149/172.0
EKDQYYNASFIPTYSPQMPIIVAEGPQRPTLTLFWQMMWQQEVSLVAMTTTIsdgsqvvgerywpsegdileigplqitlehehtnlaicerslrvKHID
| . |.|||....| . .|. || | || ||.|.... .... . |. ..
egsdyinasyldlyyipdrfiatqgplrntladfwrmlkelgithivnltel............................................lydp
LGITRDVKLLQMLFWVAGEACeDSHRFLAFAERVRDARsKLKPDQPLLVHGITAVGRAGAFCALLNLLdrfdneRRLNVVDELTRLRQARSHFISDVVY
. .| . .. | | . .. .. .| | | .... |.|. | ||| |||.|...|.. .| ..|.. . . .|..|.. . .
ellerlgiqylylpwpDhgvp.llellleflefidell.alspggpvlVHCsaGvgRtgtlvaaylml......lglsleeavalvrekRpgavqnpsq
|
|||||||||
| subfamily_Cele-PTP-13_pd | Subfamily Cele-PTP-13 | 530-693 | 7.4e-07 | 23.1 | In-house | 65-221 (281) | alignment | ||
Range on Protein: 530-693
Range on HMM: 65-221/281.0
KDQYYNASFIPTYSPQMPIIVAEGPQRPTLTLFWQMMWQQEVSLVAMTTTISDGSQVVGERYWPSEGD-ILEIGPLQITLEHEHTNLAICERSLRVKHid
.| | .| . . |...||.. | . ||.|.||.. . . | . . . |.| . |.. | .. | | .. | . .
stdyihanyirspflkrgyiltqgpkketradfwrmiwqenttaivmlcqfletnrekcaeyfprnahcclqfdklsvsyedstvnkslvttrlnlsy..
LGITRDVKLLQMLFWVAGEACEDSHRFLAFAERVRdARSklkpdQPLLVHGITAVGRAGAFCALL
| || . | . | | .| ..| ||| | ..| . |||.|.. |.
egetrlithwlwkewpdwqvpessevmlkilrkir.ars.....tppvihcsagvgrsgtlmave
|
|||||||||
| 0051429 | (Phosphotyrosine protein) phosphatases II | 531-739 | 4.2e-19 | 64.7 | In-house | 4-225 (272) | alignment | ||
Range on Protein: 531-739
Range on HMM: 4-225/272.0
DQYYNASFIPTYspqMP------IIVAEGPQRPTLTLFWQMmWQQEVSLVAMTTTISDGSQVVGERYWP-----------SEGDILEIGPLQITLEHEHT
. |.||.....| .. . || . | ||.. ... .. . . .. . .. .|||| .. ..| | .|| .|..
sgyiNardvggy...grvvkpgrlyrsggplpltaadfwrl.kelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseel
NLAICERSLRVKHI-DLGITRDVKLLQMLFWVAGEACEDShrFLAFAERVRDarsklkpDQPLLVHGITAVGRAGAFCALLNLLDRFDNERRLN------
| . | |..... . | .| | .|... |. ..... .|.. | ..| ..|.||| ..| | ..||| || ... | ..
lldyilrellltlllsagearevmhlhytdwpdhgvpqea..llellellld.......ggpvlvHCsaGkdRTGtvvallllllgvsletivddYlltn
--VVDELTRLRQARSHFISDVVYLETILACVLDYA
. . . .||..| ... . .. .. ..|...
lyleeaveelraqrpgavqteeqylflyeallell
|
|||||||||
| 0036282 | (Phosphotyrosine protein) phosphatases II | 531-727 | 1.6e-17 | 59.2 | In-house | 2-158 (174) | alignment | ||
Range on Protein: 531-727
Range on HMM: 2-158/174.0
DQYYNASFIPTYSPQMPIIVAEGPQRptltlFWQMMWQQEVSLVAMTTTISDGSQVVGERYWPSegdileigplqitlehehtnlaicerslrvkhIDLG
. |.|||.. . .|. || . ||.|.... .. | | .. . .|||.
sdyinaspldlsyitprliagqgpla.....fwemlkelgittvvmlleekelglykcinywpe................................lred
ITRDVKLLQMLFWVAGEACEDSHrFLAFAERVRDARSKlKPDQPLLVHGITAVGRAGAFCALLNLLDRFDnERRLNVVDELTRLRQARSHFISDVVY
.| . .. | |. ... ..| .| | ..|..|.|. .|. |.||| |||.|...|.. .| . |. ...| . .||. |.. . .
lerlgiqylylpwpDhgvpdlsi.llefvkfveealse.dpggpvlVHCsaGvgRtGtlvaaylmlrgll.eslvdaldlvrelRlqrpgmvqtpsQ
|
|||||||||
| 0046846 | (Phosphotyrosine protein) phosphatases II | 531-733 | 9.3e-13 | 43.8 | In-house | 12-167 (176) | alignment | ||
Range on Protein: 531-733
Range on HMM: 12-167/176.0
DQYYNASFIPTYSpqmpIIVAEGPQRPTLTLFWQMMWQQEVSLVAMTTTISDGSQVVGERYWPSegdIL---Eigplqitlehehtnlaicerslrvkhi
| ||..| .. |. || . || |..|.... ...| . |. . ... .||| .
ldyinanlilgsr....piatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpe...leklgi...........................
dlgitrdvkLLQMLFWVAGEACEDsHRFLAFAERVRDARSKlkpDQPLLVHGITAVGRAGAFCALLnL-LDrfdnERRLNVVDELTRLRQARS-HFISDV
. | |. . .... .| . | .|.|... ..| ||| .||.|...|.. | |. |.| . | ..|. |. . .
.........qylhlpwpDhgvpdl.elllellefirealke...ggpvlVHCsaGigRtgtlvaay.llel....ekglsveealalvreqRplgavqtp
VYLETILA
... .
eQyrflye
|
|||||||||
| 0044763 | (Phosphotyrosine protein) phosphatases II | 531-726 | 2.2e-09 | 32.7 | In-house | 18-158 (178) | alignment | ||
Range on Protein: 531-726
Range on HMM: 18-158/178.0
DQYYNASFIPTYspqmpIIVAEGPQrptlTLFWQMMWQQEVSLVAMTTTISDGSQVVGERYWPSEGDileigplqitlehehtnlaicerslrvkhidlg
.|.|||.| . .... |. ........ .... . |. . .. .|||.| .
sdyinaseilpg.....lylgslpp....addlellkelgithivnlteelelgflkcdpywpeeag.................................
itrdvKLLQMLFWVAGEACEDSHRFLAFAERVRDARSklKPDQPLLVHGITAVGRAGAFCALLNLLDRfdnerRLNVVDELTRLRQARShFISDVV
. . .. . ... . ||.| | ...|.. ... | ||| |||.|...|. .. . .|.. . . ..|..|. ..
.....iqylhipipDhgvpdllehflefvefieeald..ekggpvlVHCsaGvgRsgtlvaaylmkkl.....glsleeaielvrerRp.ivpnpg
|
|||||||||
| 0051082 | (Phosphotyrosine protein) phosphatases II | 531-723 | 2.2e-09 | 32.6 | In-house | 3-137 (151) | alignment | ||
Range on Protein: 531-723
Range on HMM: 3-137/151.0
DQYYNASFIPTYspqmpIIVAEGPqrptLTLFWQMMWQQEVSLVAMTTTISDGSqvVGERYWPSEGdileigplqitlehehtnlaicerslrvkhidlg
. |.|.|.. . ... || | |....... .. . . .. .|.|..|
sdyinfsyvtgg.....lyrsggp....ladflellkelgiktivnlrseeerg..ycpeylpelg..................................
itRDVKLLQMLFWVAGEACEDSHRFLAFAERVRDarsklKPDQPLLVHGITAVGRAGAFCALLNLLDRfdnerrLNVVDELTRLRQARSHFIS
..|. ...| | . . . .|.| | ..| |...|.||| .|| |...||. .| . ... . | .|. | ...
..ievlhipildwpdpglplsfdavleflellld.....kkngpvlvHCsaGkgRTGtlvalylmllg......vsleealeeyrlkrpgvvq
|
|||||||||
| subfamily_Cele-PTP-19_pd | Subfamily Cele-PTP-19 | 535-723 | 3.3e-11 | 37.5 | In-house | 79-265 (301) | alignment | ||
Range on Protein: 535-723
Range on HMM: 79-265/301.0
NASFIPTYSPQMPIIVAEGPQRPTLTLFWQMMWQQEVSLVAMTTTISDGSQVVGERYWPSE-GDILEIGPLQITLEHEHTNL--AICERSLRVKHIDLG-
| .||| |.. || . | || |. | .| ..| . . . . | | |.. .. |.|| .|....... | | .|.|.|.
hanwiptsGhphrfiatqgPlkntsedfwamlvqydvekivmlgqkvekleekceeylpvkisekldigrfkikiknkelilnkkiskrtlevedstgkf
ITRDVKLLQMLFWVAGEACEDSHRFLAFAERVRdarsklKPDQPLLVHGITAVGRAGAFCALLNLLDRFDNERRLNVVDELTRLRQARSHFIS
|| | | | . . . . | |. | ..|..|| . .||. || . | . ........ . | .||. | . .
atrtvthyqysewtdrgvPkshaelfdlmelvk......ksekPivvhcsaGiGrsvafigteylareveadptieltealkhlrehrwngvq
|
|||||||||
| 0049260 | (Phosphotyrosine protein) phosphatases II | 538-726 | 4.2e-15 | 51.2 | In-house | 1-137 (152) | alignment | ||
Range on Protein: 538-726
Range on HMM: 1-137/152.0
FIPTYSPQMPIIVAEGPQRPTLTLFWQMMWQQEVSLVAMTTTISDGSQVVGERYWpsegdileigplqitlehehtnlaicerslrvkhidlgitrdvkL
||. | .....| ..|| . || ||.|.... .. . | |. .. . |.|.
fidgyampfefiatqgpgpntladfwrmlkelgittivmltellelgklkceqyi............................................q
LQMLFWVAGEACEDSHRFLAFAERVRDArsKLKPDQPLLVHGITAVGRAGAFCALLNLLdrfdneRRLNVVDELTRLRQARSHFISDVV
. |.| . ....| .| . . .. . .|... | ||| |||.|...|.. .| ..... . . ..|..|.. .
ylhlpwpDhgvpdlsqlllflllfiekl..aldkggpvlVHCsaGvgRtgtlvaaylml......lgvsleeavalvrekRpgavpnpg
|
|||||||||
| subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 542-724 | 1.1e-07 | 25.5 | In-house | 232-423 (440) | alignment | ||
Range on Protein: 542-724
Range on HMM: 232-423/440.0
YSPQMPIIVAEGPQRPTLTLFWQMMWQQEVSLVAMTTTISDGSQVVgerYWPSEGDILEIGPLQITLEHEHTNLAICERSLRVKHI-DLGITRDVKLLQM
|| . .| .. | |. ||... . ..| . | . | . . ||| . . .||. . . |.| .|. .. |. ..
yskknafiatqmpldstvldfwrlvhdyristiimlnqlndktcsi...ywpvntrsvtfgpftvghkgsenmnrvkvrtlelkykeevheirqfevqtw
LFWVA------GEACEDSH-RFLAFAERVRDARS----KLKPDQPLLVHGITAVGRAGAFCALLNLLDRFDNERRLNVVDELTRLRQARSHFISD
|. | | |. ... . ... || . |.||| .. . .| ||...| |....|. ..| ..| || .| |.
ptwiqsdgvqsqeqcmdavlqlmdylrkceiqrsteqsrpgdgppilvhclsgieesgvfctvmncleqlnndgaidvfqnlrllrlsrpnfvpt
|
|||||||||
| subfamily_Anemone-PTP-3_pd | Subfamily Anemone-PTP-3 | 547-728 | 4e-08 | 27.7 | In-house | 6-193 (199) | alignment | ||
Range on Protein: 547-728
Range on HMM: 6-193/199.0
PIIVAEGPQRPTLTLFWQMMWQQEVSLVAMTTTISDGSQVVGERYWPS-EGDILEIGPLQITLEHEHT--NLAICERSLRVKHIDLGITRDVKLLQMLFW
|... | | |.. ||||.|. . | .. |||. | . | | .| . | . .|. | . ||.. |. |
ryiatqhplretmadfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyqftsw
VAgEACEDSHRFLAFAERVRDARSKL--KPDQPLLVHGITAVGRAGAFCALlNLLDRFDNERRLNVVDEL---TRLRQARSHFISDVVYL
. . |. | |. | . | |..|| | .| | || .. | .| . ||| . |||||| || . .
ke.kttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfval.digvrsheesktsvvdlfevakrlrqarcgiisslqhy
|
|||||||||
| subfamily_Nvec-PTP-3_pd | Subfamily Nvec-PTP-3 | 548-728 | 4.8e-08 | 27.4 | In-house | 6-192 (198) | alignment | ||
Range on Protein: 548-728
Range on HMM: 6-192/198.0
IIVAEGPQRPTLTLFWQMMWQQEVSLVAMTTTISDGSQVVGERYWPS-EGDILEIGPLQITLEHEHT--NLAICERSLRVKHIDLGITRDVKLLQMLFWV
|... | | ||. ||||.|. . | .. |||. | . | | .| . | . .|. | . ||.. |. |
yiatqhplretladfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyqftswk
AgEACEDSHRFLAFAERVRDARSKL--KPDQPLLVHGITAVGRAGAFCALlNLLDRFDNERRLNVVDEL---TRLRQARSHFISDVVYL
. . |. | |. | . | |..|| | .| | || .. | .| . ||| . |||||| || . .
e.kttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfval.digvrsheesktsvvdlfevakrlrqarcgiisslqhy
|
|||||||||
| subfamily_Cele-PTP-9_pd | Subfamily Cele-PTP-9 | 558-739 | 9e-08 | 26.5 | In-house | 40-221 (255) | alignment | ||
Range on Protein: 558-739
Range on HMM: 40-221/255.0
TLTLFWQMMWQQEVSLVAMTTTISDGSQVVGERYWPSEGDI-LEIGPLQITLEHEHTNLAICERSLRVKHIDLGITRDVKLLQMLFWVAGEACEDSHRFL
|. |.|.. |.. . |.| . . ... ..|.| | | | . ...| . .. . . . . . |..|| . |.. | |... |
tvdkfyqtivqtktevvvmlcdfaeegvekcssyfplekdeklkladvnvtttkssadvvlrtleitstlgekkkthtvkhysykGWieknaPelareil
AFAERVRDARSklkpdqpLLVHGITAVGRAGAFCALLNLLD----RFD--NERRLNVVDELTRLRQARSHFISDVVYLETILACVLDYA
|||..| ..|| | .||. || . .| . |. . |. ||. |. | . ..| . |||.
nilkvvrdsks.......vvvhCstGiGrsaafvlaelvyqkmirsldttetveldylslleelrskrkraihtPlqlafsilmvldlv
|
|||||||||
| 0048179 | (Phosphotyrosine protein) phosphatases II | 625-727 | 5.7e-07 | 24.9 | In-house | 39-133 (144) | alignment | ||
Range on Protein: 625-727
Range on HMM: 39-133/144.0
KHIDLGITRDVKLLQMLFWVAGEACEDSHRFLAFAERVRDARSklkPDQPLLVHGITAVGRAGAFCALLNLLdrfdnERRLNVVDELTRLRQARSHFISD
.. .| . .. | | .. .... .|.| | ...|.. .. | ||| |||.|...|. .. ...|.. . | ..|..|.. .
eyepefleregiqylhlpwpDhgvpdllellleflefieeale...eggpvlVHCsaGvgRtgtlvaaylmk.....klglsleealalvrsrrpgavpn
VVY
.
pgq
|
|||||||||
| 0048076 | (Phosphotyrosine protein) phosphatases II | 632-732 | 4.3e-07 | 25.2 | In-house | 44-136 (145) | alignment | ||
Range on Protein: 632-732
Range on HMM: 44-136/145.0
TRDVKLLQMLFWVAGEACEDSHRFLAFAERVRDARSKlkpDQPLLVHGITAVGRAGAFCALLNLLDrfdneRRLNVVDELTRLRQARSHFISDVVYLETI
.| . .. | | .. ... .|.| | ...|... . | ||| |||.|...|. .| ..... . | ..|..|.... . .|. .
erlgiqylylpwpDhgvpdllellleflefieealke...ggpvlVHCsaGvgRtgtlvaaylmll.....lgvsleealelvrsqrpgavpnpgqlrfl
L
.
y
|
|||||||||
| PTPc_DSPc_SM00012 | 635-736 | 3.2e-10 | 35.5 | In-house | 2-104 (105) | alignment | |||
Range on Protein: 635-736
Range on HMM: 2-104/105.0
VKLLQMLFWVAGEACEDSHRFLAFAERVRDARSKLKPDQPLLVHGITAVGRAGAFCALLNLLDRFDNE-RRLNVVDELTRLRQARSHFISDVVYLETILA
|| .... | .. |.|. .| . . |.. ..| . .|..|| . |||.| |.|| ||.....| ..... . . .||. |.. .. ...
vkhyhytgwpdhgvPeesdsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgmvqteeqylflyr
CVL
..|
all
|
|||||||||