Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
---|---|---|---|---|---|---|---|---|---|
0050432 | (Phosphotyrosine protein) phosphatases II | 103-395 | 2.1e-91 | 301.7 | In-house | 14-303 (308) | alignment | ||
Range on Protein: 103-395
Range on HMM: 14-303/308.0
ICDNAVDDLSKPIPIALFPEYVAKMHGGIRLETEYKKFNNGQQfPWGAARKPANKNKNKNRYANIVAYDHSRVVLervngDEDLDYINASFIHGYD-GTP
.|. . |..... . ... |... .||.|...... . .. .||.|||| .|..||||||.| ||. ||||||...||. . |
frdtsilvsslklsvldllkllekaldlglleeefeellsvkp.lleysvallpenkdkNrykdilpydhsRVkl.....degsdYInAsyvdgyssklp
RSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPD----KTETYGGVTVTLHQSEVFAGYENCTFILSKEKRSGSRIVRQFHFTVW
| ||| ||||| .| |||||||||.. |||||.|| .. ||..|||. ....||..|||| ||...| |..|.. . . ||.|..||.| |
rkfIatqgPlpntvedFwrmvweqnvrvIvmLtklvengrekcaqYwplelgggsleygkftvtllseevlddytvrtleltnlgdgesrtvthfhytnW
PDKGVPQYATAVLAFRRKVRALNprDAGPVIVHCSVGVERTGAYIVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTCGN
|| |||......|.| ..|| . . ||..|||| || |||..|..| .||| .| ..||. ... .|..||.||||.||| |.. |.|| | .
pdhgvPpspeilldflelvrksl..pggpivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkklReqRpgmvqtpeqylflyralleylklkl
|
|||||||||
0039614 | (Phosphotyrosine protein) phosphatases II | 107-395 | 1.6e-84 | 279.2 | In-house | 8-293 (297) | alignment | ||
Range on Protein: 107-395
Range on HMM: 8-293/297.0
AVDDLSKPIPIALFPEYVAKMHGGIRLETEYKKFNNGQQfPWGAARKPanKNKNKNRYANIVAYDHSRVVLERVNG-DEDLDYINASFIHGYDGTPRSFI
... ..|. . . . |. . .|..|... . . .. |..| .||.|||| .|..||||||.| ..| |.|.||||||.. ||| ..| ||
llesipiplsvldlllllekansktllllefeellslkp.dysiallp..enkdknrykdilpydhsrvklkpedgvdldsdYinAsyvdgydlltrkfI
ASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKtKCHKYWPDKTETYGGVTVTLHQSEVFAGYENCTFILSKekRSGSRIVRQFHFTVWPDKGVPQY
|.||||| .| ||||||||....|||||.|| |.. ||..|||....|||..|||| . |. .|| |. ... . ||.|..|..| ||| |||..
atqgPlpetvedFwrmvweqgvtvivmLtklvelgr.kcaqywpeeggtygdftvtllkvehldgytvrtlevtn..ngesrtvthfqytgwpdhgvpps
ATAVLAFRRKVRALNPR--DAGPVIVHCSVGVERTGAYIVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTCGN
.. .| | ..|| . . . |||.|||| || |||..|... |||| .| ..||. . . .|..||..||| .|| |.. |.|| | ...
lellleflelvrealaelpkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavqtpsqyrflydallellkrkl
|
|||||||||
subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 109-399 | 8.3e-130 | 427.4 | In-house | 3-298 (298) | alignment | ||
Range on Protein: 109-399
Range on HMM: 3-298/298.0
DDLSKPIPIALFPEYVAKMH--GGIRLETEYKKFNNGQQ----FPWGAARKPAnkNKNKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGYDGTPr
....... .|......|... . .....|....|.... . . .||||. ||.|||||.|.|.|.||||||....||. |||||||.|.|.|..
teieaedlkaalqklaavkkkkkltgyalefqrlnsvsseieeeekevarkpe..nkkkNRyadiialdssRvvLekedadeesdYiNAsflhaykgrn.
SFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPD-KTETYGGVTVTLHQSEVFAGYENCTFILSKEKRSGSRIVRQFHFTVWPDKG
.|||.|.||....|.|||||.|.....|||||||. |.|||.|||||| ..|||| .||.|...|.|| ........||.|....| |||.|||.|||||
afiatqaPltetvedFWrmvteedigtiVmltnleeldktkyhkywPdegketygeitvsllskeefadlivrklkvskkkeekerevrqlhftsWpdkg
VPQYATAVLAFRRKVRAlNPRDAG--PVIVHCSVGVERTGAYIVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTCGNTEIQ
||..||.||...||||| ....|| ||||.|| ||.|.|..|.||..||..||...||........||.||..|||.|||.||..||||||...|.||.
vpenatsvldllrkvra.sqqqagnkpvivqCsaGvgRsGtfiaidsvlervkkeqvvDvfqvvkvlRkkrpgavqteeqYvfiyeavlealdsfndeie
|
|||||||||
subfamily_PTPRD_pd | Subfamily PTPRD | 112-626 | 1e-247 | 818.3 | In-house | 2-514 (564) | alignment | ||
Range on Protein: 112-626
Range on HMM: 2-514/564.0
SKPIPIALFPEYVAKMH--GGIRLETEYKKFNNGQQFPWGAARKPAnkNKNKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGYDgTPRSFIASQG
|||||.| ..|.|||.. .....|.||||...||||.| ||.||| ||.|||||||||||||||||..|.|||. ||||||||.||. .....||.||
skpipvaelkehvaklkansdlkfeeeykkieegqqftweaankpa..NkaKNRyanivaYdhsRVvLskvegdegsDYINAsfidgyr.krkayIAtqg
PLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPDK-TETYGGVTVTLHQSEVFAGYENCTFILSKEKRSGSRIVRQFHFTVWPDKGVPQYATA
||....| ||||||||||..|||||.|. .|.|||||||.| |||||..||||...| .| || .||.|.|.|.| || ||||||| |||.|||..||.
PlaetiedFWRmvweqnsstiVmltkleEkgkvkchkYWPekgtetygeltVtleeeeeladyeirtfklkkkkssesreVrqFhFtsWPdhgvpesats
VLAFRRKVRALNPRDAGPVIVHCSVGVERTGAYIVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTCGNTEIQSEKYNQAMQ
.|...|||||||..||||..|||| ||.|||..||||||||..|...||||..|..|.||.|..||||.|||.|||.|.||||.|||||..||...|..|
lLdlirkvralnepdagPivVhCSaGVGRTGtfividamlerikeektvDiyqyvkalrkqRnamVqteeQYiFiheailealacgntevesenlkqhlq
KLASVNGKFPMTGYALEFQRLNsvTSREIPVEEKSVGEKPQNLHKNRFSDIIALNSCRVMLHKEHADEESDYINAVFLHAHRGRNAFIATQHPLLETVED
|||.|. .. |||..||||||. |..||..||..|..||.|..|||||.|.||.||||.|....|.||||||||..|.|.|...||||||.|| .||||
kLaeveedtemtgleleFqrLa..takeieleefavatkpknkkknrfsnilalescrvvlsairakeesdyinasyleayrekrafiatqaplkntved
FWRMVTDYDIGTIVMLNNLHDQVAPESSEYWPDHGATKYGHIGISVLSKQKKGDVICVKPKVTRKKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQT
|||||.......||||..|..... |||||..|..|||||.|.|.||.|..|.|....| ||..|.|...|..||.|...||.. .|..||||||..|..
fwrmvweeevkiivmltkleekleeesseyysdleatkyGeitikvlkkkeksdilfrkkkvevkekseavyllhtvqavdkklltvidsvldllkavrk
SQQQCGNVPVLVQCRYNK
..... .|.| .....
vleravvvrvsegvtvtg
|
|||||||||
subfamily_PTPRB_pd | Subfamily PTPRB | 112-393 | 6.7e-90 | 296.1 | In-house | 4-287 (293) | alignment | ||
Range on Protein: 112-393
Range on HMM: 4-287/293.0
SKPIPIALFPEYVAKMH--GGIRLETEYKKFNN-GQQFPWGAARKPAnkNKNKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGYDgTPRSFIASQ
|||| . | |.|.||. .|. ||..... |.. ||.... |..|||| ||..|||||| |. ...... |||||..|.|| .|| |||.|
skpiklekfeehvkkmkadsdlrfseeyeelkavgkdqavkaaelav..nraknrytnilpydhsrvkLaalkdesgsDYinanyipgyn.sprefiatq
GPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPDK--TETYGGVTVTLHQSEVFAGYENCTFILSKEKRsgSRIVRQFHFTVWPDKGVPQYA
|||| ... |||||||..|. |||||.|| |.||..|||.. . .|| ..||| ..|. . .. ..|||. .| |||.||| ||| |||. .
GPlpetvddfWrmvwekkssiivmltqlvekgkvkCeeYWPadeepvlyGdikvtlvaeeeledwvirelkiekeke..erkvrqyhftsWpdhgvPekt
TAVLAFRRKVRALN--PRDAGPVIVHCSVGVERTGAYIVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTC
...|.| |.|| ...|..|||| || |||..| .| .|.. ... .||| ....|..| ..|||..|| |||..||. |.
ktlldfvrtvreaiektaskrPivvhCsaGvGRtGtfialdrllqaieeedyvdifgivaelReeRnllvqtekqYifihqcvldllrk
|
|||||||||
subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 113-411 | 2.8e-88 | 290.9 | In-house | 4-299 (315) | alignment | ||
Range on Protein: 113-411
Range on HMM: 4-299/315.0
KPIPIALFPEYVAKMHGGIR--LETEYKKFNNGQQFPWGAARKPanKNKNKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGYDgTPRSFIASQGP
.|||. . |||. . . .. .|. || .| |.| .||.|||| ||.|||.||| | .. |.. ||.||.|| ||. .| .||.|||
qpipldqlityvaqkkastkngfkqdyesipggqlhpldvakki..enkqknryiniiaydksrvqlpllendphsdyvnanfidGyn.kkrryiaaqgp
LPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPDKTETYGGVTVTLHQSEVFAGYENCTFilSKEKRSGSRIVRQFHFTVWPDKGVPQYATAVL
.. . . |||.|.|.. |||||||| .| |. |||||| .|| .|||. . ||. | |. | .. | | |.|.| ||| |||.|.....
nvasvkdfwrlvfeedigkivmltnlvegekrkaekywpdkkviyGkitvtrkseevnteytvrtl..svvfgdnirevvqlhytswpdmgvpkytiplm
AFRRKVRALNPRDAGPVIVHCSVGVERTGAYIVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTCGNTEIQSEKYNQAMQKL
. |.|. . ..|...|||| || |||..| .||.|.||. . .|. |.. .|. | .|||. ||| ||..|.||.. ||.| | . | | . |
nlirtvkqhhtnsvgaivvhcsaGvGrtGtfitldavldqaeaenaidvynfitgvrqnrikmvqvaeqyqfiydalletfvcgdtsiaqdlylqrydsl
A
l
|
|||||||||
subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 113-415 | 2.5e-77 | 254.8 | In-house | 1-301 (315) | alignment | ||
Range on Protein: 113-415
Range on HMM: 1-301/315.0
KPIPIALFPEYVAKMHGGIRLETEYKKFNNGQQFPWGAARKPANknKNKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGYDGtPRSFIASQGPLP
.|||.| || .| | . . |.. . . . .. .||.. | .|||| ||. .|..||.|| .. . | ||||||.|...| ...|||||||.
qpipvaqfpafvnknrhtalfseefhdlpdPdiyrqrvaretin..fkknryknilPldsarvkleviddsPdsdyinasyiksvdd.dkayiasqgPlk
PAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPD---KTETYGGVTVTLHQSEVFAGYENCTFILSKEKrsGSRIVRQFHFTVWPDKGVPQYATAV
. . |||||.... .|||.|.. .| || .|||| .. .| . |.| . | .. . ... | . || | ||.|| ||||||.. ....
asvddfwrmvlqekvttivmvtkkqegdkikcrqywPdrkadsvefGsikvellsleadtdgvarklvtrkse..esrtvtqfqftewPdkGvdkqtssl
LAFRRKVRALNPRDAGPVIVHCSVGVERTGAYIVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTCGNTEIQSEKYNQAMQK
| . ..|.| | .. ...|||| || ||| | || ...|.|..|.||. |.. .|..||..|||.|.|.||. |||| | || | .. . .|
lklikevkadngkkefsllvhcsaGvGrtGvvisidevvaqikrtrsvdvfnfvknlrakrpylvqteeeyafiydavledllwrntlilvihftdhlqd
LASVNG
| . .
lhtsvd
|
|||||||||
subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 113-403 | 1.9e-74 | 245.5 | In-house | 8-296 (297) | alignment | ||
Range on Protein: 113-403
Range on HMM: 8-296/297.0
KPIPIALFPEYVAKMHggiRLETEYKKFNNGQQFPWGAARKPANK-NKNKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGYDGtprSFIASQGPL
.|||.. |. .| | . . . ....|. . .. . .| | .|.||.||. || ||| |. || | | ||.||||..|. .|..| |
rpiplsdfatlvqknr...htdvfseeflclpeaniqpqtvaekkvnfeksRYkniLPydssRvkLaivnddpdsDyvnasfvkgnkh...rlittqmPm
PPAFEGFWRMVWEQNSQSIVMLTNLVGLNKtKCHKYWPDKT-ETYGGVTVTLHQSEVFAGYENCTFILSKEKRSGSRIVRQFHFTVWPDKGVPQ--YATA
. . . ||.||.... . ||||... .| || .||.||. |.| |.|.|. . |. . .. ..|.| |.|.|..|. |||| |.. |..
katvadfWamvldeqvstivmlnddnerdk.kcaryWsdkgvttfGdvsvvllsvsereGfikrelevtkgkakarrvvkqyqfveWPdkaverkdsass
VLAFRRKVRALNPRDAG-PVIVHCSVGVERTGAYIVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTCGNTEIQSEKY
.| . || | |..|||. || ||| .. || .. .||. .||| ... .|..||..|||||||.|.. |||||| . .|.||.. .
llklisevrkdfsqnaegPllvhclaGvGrtgvlltidsvvaeakrekevdifglvkklrqerpylvqtkeqykfvyvavleallsedtriqasyf
|
|||||||||
subfamily_Urchin-PTP-4_pd | Subfamily Urchin-PTP-4 | 113-416 | 8.1e-68 | 223.6 | In-house | 2-262 (392) | alignment | ||
Range on Protein: 113-416
Range on HMM: 2-262/392.0
KPIPIALFPEYVAKMHGGIRLETEYKKFNNGQQFPWGAARKPANknKNKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGYDGTpRSFIASQGPLP
.|||.| || .| | . . |.. . . . .| .|.|. | ..|||| ||. || .||.|| .. | ||.|||.|...| ...|||||| .
qpipvaqfpafveknrhsalffeefhdlpgpdiypqtvaqkein..lkknryknilpydsarvkleviddipdsdylnasyipsfdne.kayiasqgpna
PAFEGFWRMVWEQNSQSIVMLTNLVGLNktkchkywpdktetyggvtvtlhqsevfagyenctfilskeKRSGSRIVRQFHFTVWPDKGVPQYATAVLAF
... |||||...| .|.|.|.| . | | | ||||| ||||.||......| |
aslddfwrmvfqenvttiamvtklkegd.........................................kgddartvaqfhftewPdkdvpkhtssllkf
RRKVRALNPRDAGPVIVHCSVGVERTGAYIVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTCGNTEIQSEKYNQAMQKLA-
..|.| . . |.|.||| || ||| | ||... .|||.| ||. |.. ||..||.||||||||.||. |||| | || | .. . .|.|
ikevkadfGqythpliihcsagvgrtgvvisidsvvahakktrmvdvfnfvtnirrkrpymvqtkeqyafiygavledllwrntlipvvhftdhlqdlst
SVNGK
|..|.
ssdGd
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 113-198 | 2.8e-15 | 50.6 | In-house | 4-87 (440) | alignment | ||
Range on Protein: 113-198
Range on HMM: 4-87/440.0
KPIPIALFPEYVAKMHGGIRLETEYKKFNNGQQFPWGAARKPANknKNKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGYD
.|| .| | .|| . . | |. . .| . | | | | | |||| ||.|||||||.|| |.| | ||||||.| | .
rpiivadfadyvqnnrrsrafedewsllpsglsqpsdiaslpnn..kvknryrnilaydhsrvmleevkgvpdsdyinasyingie
|
|||||||||
subfamily_Sponge-PTP3_pd | Subfamily Sponge-PTP3 | 113-209 | 1.9e-11 | 38.0 | In-house | 3-95 (95) | alignment | ||
Range on Protein: 113-209
Range on HMM: 3-95/95.0
KPIPIALFPEYVAKMHGGI--RLETEYKKFNNGQQFPWGAARKPANknKNKNRYANIVAYDHSRVVLErvnGDEDLDYINASFIHGYDGTpRSFIASQG
||| ...| .| .|| .. |.| . |. . || |||. ||. || .|||| | ||||| |. || .||.||
kpihvsvfhshvlemhsnsdqefdnefksismtsgapytvgssean..ipknrflnifpydatrvvlt...tkrdsdyinacfvdgyark.ncyiaaqg
|
|||||||||
subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 114-411 | 3.3e-83 | 274.3 | In-house | 3-303 (305) | alignment | ||
Range on Protein: 114-411
Range on HMM: 3-303/305.0
PIPIALFPEYV--AKMHGGIRLETEYKKFNNGqQFPWGAARKpaNKNKNKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGYDGTpRSFIASQGPL
.| .. . .|. |... ||..||.. . . . .| ..||.|||...|. .|..|. | . ..| ||||||...||.. ..|..||||
iialddlaayikearvysdkgleaqykslyee.eesidvgkk..eankaknrlkeitlldddriiltekeslddsdyinasyvdgykrk.kkyivaqgPl
PPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPDKTET---YGGVTVTLHQSEVFAGYENCTFILSK-EKRSGSRIVRQFHFTVWPDKGVPQYAT
. . |||...| ..|||||.|| .| ||..|||... .| ..|.|.... ...| . . .|. .. . || | |...| |||.||||.||
kntvadfWrliveekvstivmltklveggkdkCrqYWpesktekkefgefsvelksektasdyieRklkisiededkesrtvlqyqltdWPdhGvpqfat
AVLAFRRKVRALNPRDAG-PVIVHCSVGVERTGAYIVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTCGNTEIQSEKYNQA
..| . ..|. .| | |..|||| || |||..|..| .||..|| .||. ..| ..|..|. ||||..|| |.| |. | .|||.|.| . .. .
sllslikrvqkdqkkdkgvpllVhCsagvgRtGvfiavdialerlkkEevvdvfevlkqlRskrmkmvqtldqYvflhdaldelitcgdtsiigsnlrar
MQKLA
..||
vnklk
|
|||||||||
subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 114-434 | 5.5e-78 | 257.3 | In-house | 1-319 (515) | alignment | ||
Range on Protein: 114-434
Range on HMM: 1-319/515.0
PIPIALFPEYVAKMHGGIRLETEYKKFNNGQQFPWGAARKPAnkNKNKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGYDGtPRSFIASQGPLPP
|.|.| || .|.| . |.. . . .| |.. | .|||| ||. || .|| || .| . . ||.|||.|...| ...||||||..
plplaqfPafvnknrhttlfseefhdlpgpniypqtvaqeei..nfkknryknilPydsvrvklevindnPhsdyfnasyipsfdn.dkayiasqgPnka
AFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPD---KTETYGGVTVTLHQSEVFAGYENCTFILSKEKRsgSRIVRQFHFTVWPDKGVPQYATAVL
. . |||.|...| |.|.|.| .| || ||||| .. .| . | | | .| .. . |.. || | ||||| |||||||. ....|
svddfWrlvlqenvttiamvtklkegdkikcgkyWPdkpgdsvkfGsikvelvsleactggikrkltvlkgdd..srtvtqfhfteWPdkGvpkhtssll
AFRRKVRALNPRDAGPVIVHCSVGVERTGAYIVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTCGNTEIQSEKYNQAMQKL
. ..|.| . . . |.|.||| || ||| .| || .. .||..|.||. |.. ||..||..|||.|||.||. |||| | || | .. . .| |
klikevkadhgqythpliihcsaGvGrtGvvisidsvvahakttrmvdvfnfvtnirqkrpylvqtqeqyafiygavledllwrntlipvihftdhlqdl
ASVNGKFPMTGYALEFQRLNSVTS
| . . ||| |.|..
hssgdgrgrskmtkefqtlkslcp
|
|||||||||
subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 115-427 | 1.5e-96 | 318.2 | In-house | 5-319 (319) | alignment | ||
Range on Protein: 115-427
Range on HMM: 5-319/319.0
IPIALFPEYVAKMH--GGIRLETEYKKFNNGQQFPWGAARKPanKNKNKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGYDGTpRSFIASQGPLP
|... . |.. ... | || |.|........ . | |. .||.|||| ||.|||..|||| ..| |. |||||||| ||. . ||| |.||
ievqeLkerlkalastgetllekefkllkeavndtfdsaske..enkkknryqnilaydrtrvvlseldgvegsdyinasfidgyqer.ekfiatqaPle
PAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPDKT-ETYGGVTVTLHQSEVFAGYENCTFILSKEKRSG-SRIVRQFHFTVWPDKGVPQYATAVL
..| |||||||..| .||||.|| | |..||||... |.|| ..||| . | ..|. . | | . .| | .|..| |||..||..||..|
ntiedfWrmvWeeessivvmltklveklkvklkkywpeenfeeyGrlivtleeeeeledyiirklklnkkssevetRevkhfqyteWpdhdvPekatsll
AFRRKVRALNPR-DAGPVIVHCSVGVERTGAYIVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTCGNTEIQSEKYNQAMQK
.. ...| . ..||..|||| || |||..||.|||||. |. ..|. .. .| |. |||..|||.||. |.|||...|.|||. .. .. ...
dllkrirksrektqsgPivvhCsaGvGRtGtfivldamlervkeegvlDvfstvsrlRtqRnimvqrpeqYkfiyealleaveagdteievqdlrdrlkq
LASVNGKFPMTGYALEFQ
||. . . .|| . |||
laekvadtgetglerefq
|
|||||||||
subfamily_PTPRG_pd | Subfamily PTPRG | 115-405 | 2.1e-95 | 315.1 | In-house | 1-301 (563) | alignment | ||
Range on Protein: 115-405
Range on HMM: 1-301/563.0
IPIALFPEYVAKMHG--GIRLETEYK---KFNNGQQFPWGAARKPanKNKNKNRYANIVAYDHSRVVLERVNGD-EDLDYINASFIHGYDgTPRSFIASQ
.|. | ..||..| |... |.. . . .... ...|| .||.|||| ||||||.||| |. . | ..||||||..|.|| . |||.|
vpvkefakhvaslhadgdigfseefealqsetiskdldaehsqkp..enkrKnRylnivaydrsRvklsplpgkkkklDYinAnyidGyq.kskafiatq
GPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWP-DKTETYGGVTVTLHQSEVFAGYENCTFILSK------EKRSGSRIVRQFHFTVWPDKG
|||. |. ||||.||||.. |||.|||| .. ||. ||| |..|||| ..||| ..||.| | |... . ... . |||.|.| |||.|
gplkdtfddFWrmiWeqnvaiivmitnlvergrrkcdvYWPkdesetygalqvtlieeevlalytvrtlviknlklkkkkqcdteklvrqyhytkWPdhg
VPQYATAVLAFRRKVRALNPRDAGPVIVHCSVGVERTGAYIVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTCGNTEIQSE
||.... || | .| | |...|||..|||| || ||| |||.|..|.| .. .|.. . | || .|...|||.||| |.| |.|||.. ..||...|
vPehslpvLifvkkssaankaeaGPivvHcsaGvgrtGtyivldtllkqiqqenavnvfgflkhiraqRnflvqteEqYiflhdalleaiasketellae
KYNQ
. ..
qvee
|
|||||||||
subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 115-395 | 1e-66 | 219.8 | In-house | 2-287 (290) | alignment | ||
Range on Protein: 115-395
Range on HMM: 2-287/290.0
IPIALFPEYVAKM--HGGIRLETEYKKFNNGQQfPWGAARKPANKNKNKNRYANIVAYDHSRVVLERVNGDED--LDYINASFIHGYDGTpRSFIASQGP
||. | |.||. .| . ....|....|.. . . .. ...||..||.|||| || |..| ...|..| .||||..|.|| ...|| |||
ipvdkfgefvanghakgnegfrnqfkmldsges.ehtvtvgltssnkllnRfanivvyddnritLrpisghkDCtneyinAcyikgykek.kqyiatqgp
LPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPDK-TETYGGVTVTLHQSEVFAGYENCTFILSKEKR-SGSRIVRQFHFTVWPDKG-VPQYAT
.. ||...|.... |||||| . .|.||..||||. |..|| ....|.. |.. .| . .. . ... ...| |...| |...| |....|
vsntlvdFWkliwqekvtiivmltniieegkvkCqqYWpdsdtkaygefsikllneetlneyierklevknknsagakqsvtqyqitnwdstgkvtnpqt
AVLAFRRKVRALNPRDAGPVIVHCSVGVERTGAYIVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTCGN
.|.... .. | ....|||| .| |.. ..... ....|. .|. . | | .| .|||..|| .|.. ||..|.. .
illvieemyktqrkrgntsivvHCSdtvgrsavfcaaattinkcktegvidvfqvlksqRiqkpgsvqtvqqyqgifqivltyldsfe
|
|||||||||
subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 115-398 | 3.4e-66 | 218.2 | In-house | 2-285 (287) | alignment | ||
Range on Protein: 115-398
Range on HMM: 2-285/287.0
IPIALFPEYVAKMH--GGIRLETEYKKFNNGQQFPWGAARKPANKNKNKNRYANIVAYDHSRVVLErvngDEDLDYINASFIHGYDGTpRSFIASQGPLP
||. | |.||| | | .. .. ... .| . . |..||.|||...|. .| ||.|. .|. |||||.|| || . ||....|.
ipvekfgefvakghakgnegfknqftvleqvtqredevthniasqnkdknRltqilvpdnyrvllk....gehpdyinavfidgykek.kafiiaesPmf
PAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPDKT-ETYGGVTVTLHQSEVFAGYENCTFILSKEKRSG-SRIVRQFHFTVWPDKG-VPQYATAV
. ||......| . ||||... .. .|..|||... ..| ...| . || ||| . .. . .....| . |.|...| |...| |....| .
ntarnfWkliddrnvtaivmlcqekendeevcyqyWpeeksvvlGeyniellneevnagyierklevknknkagdkqqvkqyqitnWdstgkvtepqtil
LAFRRKVRALNPRDAGPVIVHCSVGVERTGAYIVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTCGNTEI
| . ..... | ....|||| .| |.. .. .. ....|. ..|. . | | .|..||| ||| || .||| |....|
lvieemyktqrkrgntsivvhCsdtvGrsamfcaaattinkckteGviDvfqvlksqriqkpgsvqtveqykfindivleyldsfetys
|
|||||||||
subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 117-429 | 2.2e-103 | 340.6 | In-house | 4-318 (318) | alignment | ||
Range on Protein: 117-429
Range on HMM: 4-318/318.0
IALFPEYVAKM--HGGIRLETEYKKF-NNGQQFPWGAARKPANKnkNKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGYDgTPRSFIASQGPLPP
. . . |... .| . |..||... . ... . . .|.|| .|||||||.||||.|| |. ..|.|. |||||..| || ...||.|.|||
vedleshvrrlresGelllseeyerlsrseetvtslkslepvnk..aknryanilaydhtrvkLqmlegeegsDyinanyidGyr.rkkayiaaqaPlpe
AFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPDK-TETYGGVTVTLHQSEVFAGYENCTFILSKEKRSGSRIVRQFHFTVWPDKGVPQYATAVLAF
..| ||||||||||. |||||... |.|.|.|||.| ...|| ..|.|... .. | .| ..... . ||.|||.|.| |||.|||. .. .|..
tieDfWrmvWeqnsavivmltqeeergkakvhryWPskgsrsygklvvelkeevelsdyvlrefkvtrteeeesrqvrqyhytsWpdegvpesgaslldl
RRKVRALN-PRDAGPVIVHCSVGVERTGAYIVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTCGNTEIQSEKYNQAMQKLA
|.|.. . . .|||..|||| || ||| .|..|..||..|. .||. .. .|..|. ||||..|| ||. ..||||..|.||..... .. ...|
vrqvskaqqksgagpivvhCsaGvGrtGvfiavdillerikaealvDvfqtvkqlreqrnlmvqtedqyefiydvllealasgdtevdasdlrsrirelr
SVNGKFPMTGYALEFQRL
.. . .| .|||||
eqdpesgttemdaefqrl
|
|||||||||
subfamily_Cele-PTP-18_pd | Subfamily Cele-PTP-18 | 125-390 | 1.4e-35 | 117.5 | In-house | 18-286 (305) | alignment | ||
Range on Protein: 125-390
Range on HMM: 18-286/305.0
AKMHGGIRLET-EYKKFNNgqqFPWGAARKPANkNKNKNRYANIVAYDHSRVVLervNGDEDLDYINASFIHGyDGTPRSFIASQGPLPPAFEGFWRMVW
|. |.| | |.||. | | | |. ...|||| .. |. || | .| .|| | .. |. || .| || . || | .
ekgpaglraefvamkrfnd...fekmkafkeaq.eagknrykdvgcldnnrvkl...egpwpheyihanyvst.ptnpkrfictqaplektcadfwymcl
EQNSQSIVMLTNLVGLNKTKCHKYWPDKT-------ETYGGVTVTLHQSEVFAGYENC------TFILSKEKRSGSRIVRQFHFTVWPDKGVPQYATAVL
... ..| || ||. ||..|.. | | ..| . |. . ... | .. . . .| | ..|. |||.||| .|.|
qdkveaifmlcnllekgakkcleyfaskdkdvlefeekgqkisvkfessvtlkfrkdakakvtetvlviegpgekarkvthyhwidwpdrgvpaadlail
AFRRKVRALNprdaGPVIVHCSVGVERTGAYIVIDAMLEQAKKSRTVDIR-NYLIAIRKHRPHMVQTKEQYSFIHSAVLEA
. | |.. ||..|||| |. |||. .... .|.| . .. | ||. | .|| .|| |.| .|.
ellekarpsk....gpivvhcsagigrtgsvvmleyildqllagqiiedtdkilqkireqrnnsiqtdaqylfvhqvilny
|
|||||||||
0047943 | (Phosphotyrosine protein) phosphatases II | 126-391 | 2.7e-83 | 274.9 | In-house | 7-272 (273) | alignment | ||
Range on Protein: 126-391
Range on HMM: 7-272/273.0
KMHGGIRLETEYKKFNNGQQfPWGAARKPANKNKNKNRYANIVAYDHSRVVLervnGDEDLDYINASFIHGYDGTPRsFIASQGPLPPAFEGFWRMVWEQ
|. | .|. |.... . . .. .||.|||| .|..||||||.| ||.. ||||||.. ||. ... ||| ||||| .| ||||||||
kllgltllleefelllslkp.lltysvallpenkdknrykdilpydhsrvkl....gdggsdyinAsyvdgynlkrk.fiatqgPlpntvedfwrmvweq
NSQSIVMLTNLVGLNKTKCHKYWPDK----TETYGGVTVTLHQSEVFAGYENCTFILSKEKRSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRALNP
|.. |||||.|| |.. ||..|||.. ..||| .|||| |....| |..|.. . . ||.|..||.| ||| |||.. . .| | ..|| .
nvrviVmLtelvelgrekcaqYwpleggelsltygkftvtllseetkddytvrtleltnlgtgesrtvthfhytgwpdhgvppslesllefielvrkale
R--DAGPVIVHCSVGVERTGAYIVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEAL
. |||.|||| || |||..|..| .|.| .| ..||. ... .|..||.|||| ||| |.. |.|| |
alpsngpvvVHCsaGvgRtgtfialdllldqlekeggvdvleavkllrsqRpgmvqtpeqyrflyealleyl
|
|||||||||
0051299 | (Phosphotyrosine protein) phosphatases II | 127-391 | 4.6e-89 | 293.9 | In-house | 19-286 (288) | alignment | ||
Range on Protein: 127-391
Range on HMM: 19-286/288.0
MHGGIRLETEYKKFNNGQQFpWGAARKPANKNKNKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGYDGTPRsFIASQGPLPPAFEGFWRMVWEQN
..| .|. |.... . . . .|..|||| .|..||||||.| ..|.|. ||||||.|.||. . . ||| ||||| .| |||||||||
angltglleefeellsllpd.ltlsaallpenleknRysdilpydhsRVkLsvldgvegsdYinAsyidgynlkrk.fIatqgPlpntvedFWrmvweqn
SQSIVMLTNLVGLNKTKCHKYWP-DKTETYGGVTVTLHQSEVFAGYENCTFILSKE----KRSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRALNP
.. |||||.|| |...||..||| ....||| .|||| ||...| |..... . . ||.|..||.| ||| |||......|.| |.|| ..
vrvIvmltklvelgrekcaqYwplggsltygditvtllseevlddytvrtlevtnldlldgdgesrtvthfhytnwpdhgvpdspellldflrlvrkala
RDAGPVIVHCSVGVERTGAYIVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEAL
. |||.|||| || |||..|..| .||| .| ..||. ... .|..||.|||| ||| |.. |.||.|
sgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlreqRpgmvqtpeqyrfvyealleyl
|
|||||||||
0043336 | (Phosphotyrosine protein) phosphatases II | 128-389 | 3.3e-84 | 277.9 | In-house | 17-275 (278) | alignment | ||
Range on Protein: 128-389
Range on HMM: 17-275/278.0
HGGIRLETEYKKFNNGQQFPWGAARKPANKNknKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGYDGTPRsFIASQGPLPPAFEGFWRMVWEQNS
. .|. |...... . ... |..|.||. |||| .|..||||||.|. ..||.|.||||||.. ||. ... |||.||||| .| |||||||...
nlktllllefeellsfkldtysiallpenkd..knrykdilpydhsrvklsllggdldsdYinAsyvdgynvprk.fiatqgPlpetvedFwrmvwelgv
QSIVMLTNLVGLNKTKCHKYWPDKTETYGGVTVTLHQSEVFAGYENCTFILSKEKRSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRALNPRDAGPV
..|||||.|| |...||..|||....|||..|||| |....| |. ... . . ||.|...|.. ||| ||| . .| | ..|| .. . |||
ttivmLtelvelgrvkcaqYwpggsltygdftvtllkeehlddytvrtlevtnlgdgesrtvthyhylgwpdhgvpeslsllldflkavrealedsngpv
IVHCSVGVERTGAYIVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLE
.|||| || |||..|... .|||..| ..||. . . .|..||..||| .|| |.. |.||
lVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqRpgavqtpsqyrflyealle
|
|||||||||
0045450 | (Phosphotyrosine protein) phosphatases II | 128-391 | 1.1e-80 | 266.9 | In-house | 24-304 (307) | alignment | ||
Range on Protein: 128-391
Range on HMM: 24-304/307.0
HGGIRLETEYKKFNNGQQF-PWGAARKPANKNKNKNRYANIVAYDHSRVVLERVNGD-EDLDYINASFI--------HGYDGtPRSFIASQGPLPPAFEG
. .|. |..|... . | .. .||.|||| .|..|||.||.| ..|. || ||||||.. .||| .| ||| ||||| .|
dfltgllkefekllsvtvfllgeysiallpenkdknrykdilpydhtRVklssldgsledsdYiNAsyvrvpllllldgydl.krkfIatqgPlpetved
FWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPDK--TETYGGVTVTLHQSEVFAGYENCTFILSKE-KRSGSRIVRQFHFTVWPDKGVPQYATAVLAFRR
||||.|||... |||||.|| |.. ||..||||. . ||| .|||| |. .|| |. .. . . ||.|..||.| ||| |||.. .|.| .
FwrmlweqgvtvivmltelvelgrekcaqywPdegeeltygnftvtllseehldgytvrtlevtdldgtgesrtvthfhytgwpdhgvppsfeelldfie
KVRALNPR--DAGPVIVHCSVGVERTGAYIVIDAMLEQAKKSRT---VDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEAL
.||. . . . |||.|||| || |||..|... ||.| .| | ||... . .|..||..||. ||| |.. |.|| |
evrkaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrflyeallell
|
|||||||||
0040438 | (Phosphotyrosine protein) phosphatases II | 129-409 | 2.8e-91 | 301.4 | In-house | 17-294 (317) | alignment | ||
Range on Protein: 129-409
Range on HMM: 17-294/317.0
GgIRLETEYKKFNNGQQFPWGAARKPANKNknKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGYDGTPRsFIASQGPLPPAFEGFWRMVWEQNSQ
.|. |.... . . .. |..|.||. |||| .|. ||||||.| ..||.|.||||||...|.. ... ||| ||||| .| ||||||||...
f.talleefedllslkldtysvaelpenkd..knrypdilpydhsRVkLsplggdldsdYInAsyvdgpnlkrk.fIatqgPlpntvedFwrmvweqgvt
SIVMLTNLVGLNKTKCHKYWP-DKTETYGGVTVTLHQSEVFAGYENCTFILSKEKRSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRALNPRDAGPV
.|||||.|. |.. ||..||| ..| |||..|||| . |. ||.. |. ... . | ||.|..||.| ||| |||.. . .|.| ..||. .... |||
vivmLteleelgrekcaqYwplgetltygdftvtllseeelagitlrtlevedlgdsesrtvthfhytgWpdhgvppspdllldfleavrealedpggpv
IVHCSVGVERTGAYIVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTCGNTEIQSEKYNQAMQK
.|||| || |||..|... |||| .| ..||. . . .|..||..||| ||| |.. |.|| |....| . .. ...|
lVHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrflydalleylkrkltlepaselklkllk
|
|||||||||
subfamily_PTPRK_pd | Subfamily PTPRK | 130-408 | 9e-90 | 295.7 | In-house | 21-294 (314) | alignment | ||
Range on Protein: 130-408
Range on HMM: 21-294/314.0
GIRLETEYKKFNNGqqfpWGAARKpaNKNKNKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGYDgTPRSFIASQGPLPPAFEGFWRMVWEQNSQS
| . ||. . .| | ||.| ..|..|||. .|.|||.|||.| ..|| . |||||..| .| |. ||. ||||. . |||.|...|. |
gygfkeeyeslfeg....wdaakk..denreknrsgdilaydrsrvflitidgdpssdyinaalidsyk.rpaafivtqgPlqetvkdfWrlvydencas
IVMLTNLVGLNKTKCHKYWPDKTETYGGVTVTLHQSEVFAGYENCTFILSK--EKRSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRALNPRDAGPV
|||||.|| . || ||||..||.|| . |.| ..|. | . . .| ..| . .. |.||||.|. ||| .||..||..|.. |.| . .. .||..
ivmltelvevgrvkClkyWPedtevygdikvelvetellaelvvrifrveklargqeeirevrqfqflgWpdhdvPvsatgllklvrrvkksqeeeaGri
IVHCSVGVERTGAYIVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTCGNTEIQSEKYNQAMQ
.|||| | |||..|.|| .|. ... ..||. | ..|.... ||.|.||| ||. ..||| ||.| | ... .
vvhCsaGaGrtGtfiaidivldmieregvvdvfnavktlrsrkvnmveteeqykfiydvileaclcgetaipvsefkalyl
|
|||||||||
subfamily_Ptp69D_pd | Subfamily Ptp69D | 132-410 | 3.4e-80 | 264.4 | In-house | 23-305 (307) | alignment | ||
Range on Protein: 132-410
Range on HMM: 23-305/307.0
RLETEYKKFNNGqQFPWGAARKPANKNKNKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGYDGTpRSFIASQGPLPPAFEGFWRMVWEQNSQSIV
|. ||.| .. ... . . |. |||| .|.|.|. ||.|...||.|| ||||||||.||. . ..|||.|.|. . ||||..||... ||
glakeyekLear.eidkstkvsekkenalknRyedikafDktRvkLkkingkedsdYinasfikgykek.kkfiaaqdPveatigDfWRmiaeqevtliv
MLTNLVGLNKTKCHKYWP-DKTETYGGVTVTLHQSEVFAGYENCTFILSKEKRSG-----SRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRALNPRDAG
||.|| |. ||.|||| ... || . |.| ..| | . .. .|| | .. || | |.|.| |.| ||. |...| . ..|| |. . .
mlsnlteknrkkcakYWpiedevqygdilvklvseekhsdyiiReldvskkkeesgevedsrkvvqyhytgWkDskvPevargllklieqvrelyklnrs
PVIVHCSVGVERTGAYIVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTCGNTEIQSEKYNQAMQKL
|..|||| ||.|.| .. .| .|.| |. .||| . .|..|. .|| |||.|.. |.|. . |.|... .....|...|
PivvhCsaGvgrsgifvaldsllqqlkaedkvdifetvkdLrsqRnllvqsleqYvflyralldyssygdtdedvddledaierl
|
|||||||||
subfamily_PTPRN_pd | Subfamily PTPRN | 132-390 | 9e-62 | 203.4 | In-house | 30-291 (297) | alignment | ||
Range on Protein: 132-390
Range on HMM: 30-291/297.0
RLETEYKKFNNGQQFPWGAARKPANKNKNKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGYDGTPRSFIASQGPLPPAFEGFWRMVWEQNSQSIV
||| |.. . . .. | .. |.|| .|||......|||||| |.. . .|. ||||||.| | ..||.||||. ||.||||| . ||
rlekewealcayeaepstkevakaeknvkknrskavlpydhsrvklkeeasaeksdyinasaildhdprapayiatqgplastvadfwqmvweqGvvviv
MLTNLVGLNKTKCHKYWPDK-TETYGGVTVTLHQSEVFA-GYENCTFILSKEKRSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRALNPRDAGPVIV
.||.| . ..|..||||. .|.|. | | ... | .| | . | .| | |||| ||..||| | ..| ||||| . |..|
nltrleeegvkqckrywpdeGsevyhiyevhlvsehiwcddylvrsfylknlqtsetrtvtqfhflswpeegvPasaksllefrrkvnksyrGrscpivv
HCSVGVERTGAYIVIDAMLEQAKK-SRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEA
||| |. |||.||.|| .|.. .| . .|| | .| ||..|.||.|. |. .|| |
hcsdGaGrtGvyilidlvlnrllkGvkeidiaatlehlrdqrpglvktkdqfefaltavaee
|
|||||||||
subfamily_PTPN23_pd | Subfamily PTPN23 | 132-390 | 6.4e-57 | 187.6 | In-house | 16-279 (288) | alignment | ||
Range on Protein: 132-390
Range on HMM: 16-279/288.0
RLETEYKKFNNGQQFP-WGAARKPANKNKNKNRYANIVAYDHSRVVLErvnGDEDlDYINASFIHGYDGTPRSFIASQGPLPPAFEGFWRMVWEQNSQSI
|....|.... |. . . |... .|||. .|. |||.||.|. | .| |||||||... . .|||.|.||... ||.||.|| |. |
aldkkfkeleqkqdkearkrsiaiaklyseknrsrdilPyDhnRvklr...gskD.DYinAsfvkdlspgcPdfiatqaPlqstlnDFWlmvyeqkssvi
VMLTNLVGLNKTKCHKYWP---DKTETYGGVTVTLHQSEVFAGYENCTFILSKEKRSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRA----LNPRD
|||.. |.|.|...||| ..|...| ..|||.. . . . ...|. .. . . |. ..| ||. |||. .|.| .|.. . .
VmllskeelgkpkvdrYwPedkgetvkfgdlsvtlksvretethvervlkletldadavksvshlqltsWpelGvPasPetllqfldevesayeavqrks
AGPVIVHCSVGVERTGAYIVID-AMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEA
|..|||| ||.|||.. .. |. | |. .|| . . .|. | .|||.|||. | .|||||
ktPlvvhCsaGvgRtgvfalvyaavrelekgnglldiiqvvsrlreqRrfmvqekeqlkfsyeavlea
|
|||||||||
0046845 | (Phosphotyrosine protein) phosphatases II | 133-396 | 3.2e-86 | 284.5 | In-house | 2-279 (284) | alignment | ||
Range on Protein: 133-396
Range on HMM: 2-279/284.0
LETEYKKFNNGQQFPW-GAARKPANKNKNKNRYANIVAYDHSRVVLERVNGD-EDLDYINASFIHGYD----GTPRSFIASQGPLPPAFEGFWRMVWEQN
|| |... .. . ... . .|..|||| .|..||||||.| ...|| || ||||||...||| ... ||| ||||| .| |||||||||
leeefeellsltvklllslsvallpenlsknRykdilpydhsRVklksldgdledsdYinAsyvdgydldltyikkkfIatqgPlpntvedFwrmvweqn
SQSIVMLTNLVGLNKTKCHKYWPDK--TETYGGVTVTLHQSEVFAGYENCTFILSKEK-RSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRALNP--
.. |||||.|| ...||..|||.. . |||..|||| ||. .| |. |.... . ||.|..||.| ||| |||.... .|.| |.|| |..
vrvIVmltelvengrekcaqYwplegevltygdftvtllseevkddytvrtleltnlgytgesrtvthfhytswpdhgvppspedlleflrlvrellenl
RDAGPVIVHCSVGVERTGAYIVIDAMLEQAKKSR---TVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTCGNT
. ||..|||| || |||..|..| .||| .| . .||. ... .|..||.|||| ||| |.. |.||.| ...|
pgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvqtleqyrfvyealleylklklt
|
|||||||||
subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 133-392 | 6.7e-84 | 276.3 | In-house | 17-277 (281) | alignment | ||
Range on Protein: 133-392
Range on HMM: 17-277/281.0
LETEYKKFNN-GQQFPWGAARKPAnkNKNKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGYDGtPRSFIASQGPLPPAFEGFWRMVWEQNSQSIV
. .||.|... |.. . |..... |..|||| ||||||..||.... . ... |||||.|. ||.| .. .||.|||.| ... ||.|||||. . ||
fieeyeklaaigvdntataskade..nvlknrYsnivaYDatrvkvtpneenkntDYinanfvpgykg.ekeyiatqgPvPaslvafWqmvweqkvsaiv
MLTNLVGLNKTKCHKYWPDKT--ETYGGVTVTLHQSEVFAGYENCTFILsKEKRSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKV-RALNPRDAGPVI
|.|. . .| |||.||||.. .|| |||. ...| | | . .| | ... . .| |.|...| |||.|||. ....| ||..| .. ... |..
mvtreieagklkChrYWPddnselkygdvtvkstaeeekatyierkfkl.eresgetreveqlaytaWPdhGvPattkellefrkevlkltekktkaplv
VHCSVGVERTGAYIVIDAMLEQAK-KSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALT
.||| || |||.|| .| ...... . ...|... . .||.| |||| ||.|.. |||.||
ihCsaGvGrtGtyialDrlvkaveaeleeldvkavvaelrkernlmvqtvvqyefvykavldald
|
|||||||||
subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 133-390 | 6.9e-80 | 263.2 | In-house | 23-278 (288) | alignment | ||
Range on Protein: 133-390
Range on HMM: 23-278/288.0
LETEYKKFNN-GQQFPWGAARKPanKNKNKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGYDGTpRSFIASQGPLPPAFEGFWRMVWEQNSQSIV
.. ||.. . ... |.|.. .|..|||| ||..||. || |. .. .. ||||||.|.|.... . .||.||||. . . ||..|.|.... ||
fseeynsLaalektksvtagrla..vnakknRyrnilpyDekrvklkkleeeagaDYinasyidgekkk.kkyiatqgPladtvndfWelvyenktstiv
MLTNLVGLNKTKCHKYWPDKTE--TYGGVTVTLHQSEVFAGYENCTFILSkeKRSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRALNPRDAGPVIV
|||.|| .||||..||||. . || ||||| .|. . . ...| |. . . . |.....|||.|||. .. .|...|.| |. |.||.||
mltelveggktkCeeYWPdadkpknyGsvtvtlveskeledfvlrkllle..kkkteleitqyqylaWpdhgvPeskapllellrqvkvanqadtgpiiv
HCSVGVERTGAYIVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEA
||| || ||| .|..||.... ... ..|. . . .||.|. .|||..|| ||....|.
hCsaGvGrtgtFialdalidaveeedyiDvagtvaklRkqRallvqtlkqYefiyevllsl
|
|||||||||
subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 133-410 | 2.6e-76 | 252.0 | In-house | 36-310 (319) | alignment | ||
Range on Protein: 133-410
Range on HMM: 36-310/319.0
LETEYKKFNNGQqfPWGAARKPA--NKNKNKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGYDgTPRSFIASQGPLPPAFEGFWRMVWEQNSQSI
|| |... . . .| .. | ..||.|||. ||.|.|...| |||..| | |||||||. || . .||.||||. . . ||||.||.|. .|
levefrracklg..vnladqtfanldqnkdknriinilafdknvvklerliGeefsdyinasfvtGyq.rkdkyiaaqGPldntladfWrmiweyncsti
VMLTnlvglnKTKCHKYWPDKT-ETYGGVTVTLHQSEVFAGYENCTFILSK-EKRSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRALNPRDAG--P
|.|| | || .||| |. .... | .. | | | . ||. | . | ..|||| |||.|||.|.. .. . .||| |. . . .
vllt......kdkcsqywplkivikeerfkvkvdsveetaeyvvrdielsedgkekdirkitqfhflGwpdvGvpdypsdlmrlvkkvrhltskenhran
VIVHCSVGVERTGAYIVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTCGNTEIQSEKYNQAMQKL
..|||| || |||.|||.|..|.. |. . ||. |.. .|. |...|| || ||.||.|| |.... . ...|
ivvhcsaGvGrtGvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysalleehlfghsdvampdfpayleel
|
|||||||||
subfamily_PTPN12_pd | Subfamily PTPN12 | 133-392 | 5.6e-72 | 237.1 | In-house | 17-278 (290) | alignment | ||
Range on Protein: 133-392
Range on HMM: 17-278/290.0
LETEYKKFNNGQQFPWGAARKPanKNKNKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGYDGTpRSFIASQGPLPPAFEGFWRMVWEQNSQSIVM
| .. .|. . .... |..|. .|..|||| .|. ||.|||.|.. ...|. |||||.||.| .|. ..||.||||| . . ||||.||.| . .||
lkklsekykaekvysteageke..envkknrykDilPydksrvelskieeeegsdYinanfikgvegk.leyiaaqgPLpktlddfWrmiweknveivvm
LTNLVGLNKTKCHKYWPDKT---ETYGGVTVTLHQSEVFAGyENCTFILSKEKRSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRALNPRDAGPVIV
. ..| |.|.||..|||... ..| ..|||.. . . . | |... ||.|.|||.| |||.|||. |. .|.. ..|| |. ... |..|
aCrevelgkkkCerYWpeegeeelefgefevtleeekavdd.dflirtLkveaqkesrkvyqfhYtaWPDhgvPssaksllelielvrelqesedaPlvv
HCSVGVERTGAYIVIDAMLEQ---AKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALT
||| || |||. |.|| . |. | . ..|. . .. .||.|. .|||||||.... ||.| ..
hCsaGvGrtGtiiaidyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavaelvq
|
|||||||||
subfamily_PTPN9_pd | Subfamily PTPN9 | 133-389 | 4.3e-67 | 221.2 | In-house | 18-288 (297) | alignment | ||
Range on Protein: 133-389
Range on HMM: 18-288/297.0
LETEYKKFNNGQqfPWGAA-RKPANKNKNKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGYDgTPRSFIASQGPLPPAFEGFWRMVWEQNSQSIV
| ||.. | . . | . . . | .||||.... ||..||||..|..|| |||||.|. || ...||| ||||. ... ||||||||. ||
lskeyaeirnep..veGtflasklranleknrytdvlcydetrvvlakvdedeasdyinanfvdGyk.qkkafiatqGplkktvsdfWrmvWeqevlviv
MLTNLVGLNKTKCHKYWP---DKTETYGGVTVTLHQSEVFAGYENCTFILSKEKRSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRA--------LN
| | .| . || .||| .... .| ..|. . |. |. .. ... | . || | | |. ||| |||. |...| ...||| |
mttrvvergrlkcgqyWpleeessaefgdlsvsnveveeeedykvrvleiknvkteesrkvthfqflsWPdyGvPssaaslldvlekvrekqalavkelg
PRDA-----GPVIVHCSVGVERTGAYIVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLE
.... |..|||| |. |||..| .| |.. .. |||... . .|. | ...|| ||| | . ||||
dewkghpsgPPivvhcsaGiGrtGtfitldiclsrleevgtvdvvetvkllrtqrafsiqtpeqyefcylavle
|
|||||||||
subfamily_Sponge-PTP9_pd | Subfamily Sponge-PTP9 | 133-397 | 5.4e-54 | 177.9 | In-house | 17-299 (301) | alignment | ||
Range on Protein: 133-397
Range on HMM: 17-299/301.0
LETEYKKFNNGQQFPWGAARkpANKNKNKNRYANIVAYDHSRVVLERVNG--DEDLDYINASFIHGYDGTpRSFIASQGPLPPAFEGFWRMVWEQNSQSI
.| .||. ..|.. . ..||. ||. ||. ||. |..|. . .|||||.|.|| . . |||.|||. |||..|.. .||
feeqykelkegedksctvgl..seenkalnrfknitvyddnriilkpkpnldlcqreyinasyidgysek.kkfiaaqgpmkktlvdfWrliwqekpvsi
VMLTNLVGLNKTKCHKYWPD---KTETYGGVTVTLHQSEVFAG-----------------YENCTFILSKEKrsGSRIVRQFHFTVWPDKGV-PQYATAV
||.||| |.||..|||. ..|..| .||||... |. | . .| ...| |. | |.. | ||. || ....| .
vmvtnlkegtkskceqywpnseaeseefgpftvtlvneqvyPdfvirqlnvkiqdgsnngyierkfkvksdk..sswdvlqlqvtdWpqdGvvreprtvL
LAFRRKVRALNPRDAGPVIVHCSVGVERTGAYIVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTCGNTE
. . . . . |||.|||| .| |.| |. .. |||.| ||. . |.|. .| .|.| |||..|. .. . |.. .|.
qviddvihrqqkigggpvvVHCSdtVsrsGvYcsvsiglEQckaegVVdvfqvtkavrrskpgaVtTLeqytsiydvidmylqlnsty
|
|||||||||
DSPc_SM00195 | 134-391 | 6.6e-80 | 263.6 | In-house | 3-262 (263) | alignment | |||
Range on Protein: 134-391
Range on HMM: 3-262/263.0
ETEYKKFNNGQQFPwGAARKPANKNKNKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGYdGTPRSFIASQGPLPPAFEGFWRMVWEQNSQSIVML
..|..| .. .. . .|||.|||| ||. |||.|| |.. ...|. |||||..| |. ....|| ||||| .| |||||||.... ||||
keefekleestspk.etteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikga.nkkkkyIatQgPlpstvedFWrmvweekvkiivml
TNLVGLNKTKCHKYWPDK---TETYGGVTVTLHQSEVFA-GYENCTFILSKEKRSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRALNPRDAGPVIV
|. . .|.||..|||.. .||.| ..|.| . | .. |. |.||... .| |.|.... |||.|||. .. ||.. |.|. . . ||..|
teeeengkekcdrywpeesggketfgkisvklvevekkkdeiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkkskstssgpivV
HCSVGVERTGAYIVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEAL
||| ||.|||....|| .|.. .. .||| . . ..||.||.||||.|||.||. |.||..
hCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaileyi
|
|||||||||
PTPc_SM00194 | 134-391 | 6.6e-80 | 263.6 | In-house | 3-262 (263) | alignment | |||
Range on Protein: 134-391
Range on HMM: 3-262/263.0
ETEYKKFNNGQQFPwGAARKPANKNKNKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGYdGTPRSFIASQGPLPPAFEGFWRMVWEQNSQSIVML
..|..| .. .. . .|||.|||| ||. |||.|| |.. ...|. |||||..| |. ....|| ||||| .| |||||||.... ||||
keefekleestspk.etteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikga.nkkkkyIatQgPlpstvedFWrmvweekvkiivml
TNLVGLNKTKCHKYWPDK---TETYGGVTVTLHQSEVFA-GYENCTFILSKEKRSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRALNPRDAGPVIV
|. . .|.||..|||.. .||.| ..|.| . | .. |. |.||... .| |.|.... |||.|||. .. ||.. |.|. . . ||..|
teeeengkekcdrywpeesggketfgkisvklvevekkkdeiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkkskstssgpivV
HCSVGVERTGAYIVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEAL
||| ||.|||....|| .|.. .. .||| . . ..||.||.||||.|||.||. |.||..
hCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaileyi
|
|||||||||
subfamily_PTPN1_pd | Subfamily PTPN1 | 141-399 | 2e-64 | 212.1 | In-house | 17-281 (290) | alignment | ||
Range on Protein: 141-399
Range on HMM: 17-281/290.0
NNGQQFPWGAARKPANknKNKNRYANIVAYDHSRVVLERVNGdedlDYINASFIHgYDGTPRSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLN
.. ..|| .|..|.| .|.||| .. |||||..||| . ||||||... . ||.| .||||| . . ||.|||||.|...||| ..| .
keasdfptreaklpen..rnlnryrdvspydhsrikleradn....dyinaslve.leeakrsyiltqGPlpntvdhfWqmvWeqkskavvmlnkvveke
KTKCHKYWPDKTE----TYG--GVTVTLHQSEVFAGYENCTFILSKEKRSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRAL--NPRDAGPVIVHCS
..||..||| . | .. ..|.| . |. | .. | . | .| . .||.| ||| |||. .| | | ||| .| ||...|||
qikcaqywPqgeeekellledtklkvkliseerksyytvrllelenlktqetreilhfhyttwpdfgvpespaaflkflfkvresGslssdvGpavihcs
VGVERTGAYIVIDAMLEQAKKSR---TVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTC--GNTEIQ
|. |.|.....|..| . .|. .|||.. |...||.| ..||..| | . |.|| . |.. .|
aGiGrsGtfclvdtclvliekkddlssvdikkvllelrkyrlGliqtadqlrfsylaileGakvikgdssvq
|
|||||||||
subfamily_Cele-PTP-6_pd | Subfamily Cele-PTP-6 | 145-391 | 1.2e-40 | 134.5 | In-house | 28-277 (307) | alignment | ||
Range on Protein: 145-391
Range on HMM: 28-277/307.0
QFPWGAARKPANKNKNKNRYANIVAYDHSRVVLErVNGDeDLDYINASFIhGYDGTPRSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKC
. | | . . . | .|||| .. . |..|.|.. ..| ||| | .. | |. ||..|||| . || |. ... .|..|| ... | | ||
ktpegvtveafsantdknryqdvkcqdkgrivvk.fdgl.asdyihanyl.giaikpkkficaqgplentqysfwamaiqekvesvimlckvielakikc
HKYWPD---KTETYGGVTVTL----HQSEVFAGYENCTFIL--SKEKRSGSRIVRQFHFTVWPDKGVPQYATAVLAFrrkVRALNpRDAGPVIVHCSVGV
..||| .. ..| . |. .. .| |.. . . ..|| .... .. |||.|||| . . . . | . | ||.|||| ||
eqywpleegqklvfgeapntisvanlgakklapdedlinvttlkvdwaqksrtiqhlqwenwpdrgvpqinltainl...leavr.ydtnpvvvhcsaGv
ERTGAYIVIDAMLEQAKKS-RTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEAL
|.|. . | . .. . |... . .|..|.. .||. || ..| .|| .
GrsGtivaislvqdkmiaGinckdmkklveelrsqrhyaiqteaqylylhrvlleyf
|
|||||||||
0036941 | (Phosphotyrosine protein) phosphatases II | 147-402 | 9.9e-86 | 283.0 | In-house | 28-288 (297) | alignment | ||
Range on Protein: 147-402
Range on HMM: 28-288/297.0
PWGAARKPANKNKNKNRYANIVAYDHSRVVLervnGDEDLDYINASFIHGYDGTPRsFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHK
.. .|..|||| .|..|||.||.| .||. ||||||.. ||| . . ||| ||||| .| |||||||||...|||||.|| |.. ||..
lgslsvallpenleknRykdilpydhtRVkl....ddegsdYinAsyvdgydlkrk.fIatqgPlpntvedFWrmvweqnvtvIvmltelvelgrekcaq
YWP---DKTETYGGVTVTLHQSEV--FAGYENCTFILSKEKRSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRALNPR--DAGPVIVHCSVGVERTG
||| ... |||..|||| || ...| |. ... . . ||.|..||.| ||| |||.... .|.| ..|| .. . |||.|||| || |.|
ywpleegesltygdftvtllsvevvllddytlrtlevtdtgngesrtvthfhytgwpdhgvpespaslldfielvrkvlkllpsggpvlVHCsaGvgRsg
AYIVIDAMLEQAK---KSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTCGNTEIQSEK
..|..| ||.| . | ..||| ... .|..||..||| ||| |.. |.|| | ...| .. |
tfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyeallellkkkltkepllk
|
|||||||||
subfamily_PTPN3_pd | Subfamily PTPN3 | 148-390 | 1.4e-63 | 209.5 | In-house | 33-274 (280) | alignment | ||
Range on Protein: 148-390
Range on HMM: 33-274/280.0
WGAARKPANKnkNKNRYANIVAYDHSRVVLERVNGdedlDYINASFIHG-YDG--TPRSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKC
|||||.| .|||| .|..||. || |. . |||||... .. . .||.||||. . . ||.|||||.|. |||||.|| ..||
isaarkpenl..sknryrdilpydatrvklkeset....dyinanyvnmeipstglvnryiatqGPlaktatdfWqmvweqksslivmlttlverGrvkC
HKYWPDKTE--TYGGVTVTLHQSEVFAGYENCTFILSKEKRSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRALNPRDAGPVIVHCSVGVERTGAYI
|.|||.... .||. .|...... | ..|.... . .| . |. .. |||.|||. .. .| | ..||.| . ||.|||| |..||| .|
hqyWPetedeleygefsvkcekedetksyvlrelvlkdketkeerkilqlqylaWpdhgvPddsadflefvervrklrsgkeePvvvhCsaGigrtGvli
VIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEA
... | ... | . . . .| | .|||..|| |. |.|..
lletalalieaaepvypldivrtmrdqramlvqtasqykfvCeailkv
|
|||||||||
subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 149-420 | 7.8e-67 | 220.7 | In-house | 41-314 (325) | alignment | ||
Range on Protein: 149-420
Range on HMM: 41-314/325.0
GAARKPANKnkNKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGYDGTpRSFIASQGPLPPAFEGFWRMV--WEqnsQSIVMLTNLVGLNKTKCHK
.| ||.|| .|||. |.||.|.|||||| . | . ||||||... . . |.|.| ||. . . .||.| |. |.|...| . |.| .| .
kvamkpenk..aknrfknvvaldksrvvletkkddpssdyinasylrddkkk.dvflaaqaPltatindlWrlvldWr...csvvvvlneldlgkdrcav
YWPDK---TETYGGVTVTLHQSEVFAGYENCTFILSKEKRSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRAL------NPRDAGPVIVHCSVGVER
|||.. . |.||. | | | .. | . . . |. .| |.||.. |.| ||... ...... . | |. | . ..|..|||| || |
ywpkemgksktfGglevklrtieeisdyvhrvldvkqvkkGetrsvkqfqlqswddmGvqkrpatlisilqlvkavservtantkastpilvhcsaGvGr
TGAYIVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTCGNTEIQSEKYNQamqKLASVNGKFPMT
||..| . ..|.. . ||| ... .||.|| ||.| .||..|. |. ||. .|||.. .. ||.|.. . |.|
tGvfislysalakvieesrvdifgfvkklrkdrpsmvetvdqyiliyealveaymsgntdvpvssfea...klsslqernplt
|
|||||||||
subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 150-388 | 1.1e-49 | 163.7 | In-house | 32-274 (287) | alignment | ||
Range on Protein: 150-388
Range on HMM: 32-274/287.0
AARKPANknKNKNRYANIVAYDHSRVVLErVNGDEDLDYINASFIHGYDGTpRSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWP
|| . |. .|||||... .|..||.| .|. ||||| .. .| .|||.|||.. . |||.|.|..| |....| | . ||.||||
aaeelaa..vkknryadvlPiddtrvlls.aegelGsdyinanyvasytdd.eafiaaqgPiaatvrdfwravletrsasvitmtreveearlkcykywP
DKTE--TYGGVTVTL-HQSEVFAGYENCTFILSKEKRSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKV-----RALNPRDAGPVIVHCSVGVERTGAY
.. || .|.| .. | .. | . . .|.|.|... ||||... | ... | .| | . ..||..||..||. |.| .
erevPmrvGGysvvlldydikePeygvralrlidletrearvvkqldllswPdkvlaPtavglirfvldvkqhielardasevGPlvvhddvGiGrsGil
IVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVL
. . ..... .. ||. . .| .|..| .||. |. .. |.
latlvlvsrledlGrvdvaavvirlreyraalvqavvqlrllyealv
|
|||||||||
subfamily_Cele-PTP-10_pd | Subfamily Cele-PTP-10 | 150-390 | 9e-34 | 111.5 | In-house | 47-288 (305) | alignment | ||
Range on Protein: 150-390
Range on HMM: 47-288/305.0
AARKPANKNKNKNRYANIVAYDHSRVVLERVNgdeDLDYINASFIHGYDGTPRSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWP
| . |. .. ||||... . |.| | |.. . ||| | .. . ||..|||| . . || || ... . |||| . | | | || .|||
nanqsadiaitknryqdvpcqdqsavkldkps...psdyihanyvgcpmipekrficaqgpldqtidefwwmviqnkveqivmlcktvelgklkcaqywp
----DKTETYGGVTVT-LHQSEVFAGYENCTFILSKEKRSGSR--IVRQFHFTVWPDKGVPQYATAVLAFRRKVRAlnprDAGPVIVHCSVGVERTGAYI
.| | .|. | . | . . | . ||.. ||....| |||.||| . | . .| |..|||| |. |||. .
aaqgeklelksgivvenvsgskpmerdaeiqitllnltysgdqkmsvrhlqwtewpdrgvppckltslellsairg....skvpivvhcsagigrtgtiv
VIDAMLEQAKKSR-TVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEA
|. .||. . . . . . |.| .| . .|. || ||| .|.
aieyilekiaenkpcppmpelvkalrdqrafsiqndvqylfihrvmlny
|
|||||||||
subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 150-315 | 2.7e-29 | 97.0 | In-house | 27-192 (297) | alignment | ||
Range on Protein: 150-315
Range on HMM: 27-192/297.0
AARKPANknKNKNRYANIVAYDHSRVVLERVNGDEdlDYINASFIHGY-DGTPRSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYW
.|.... |||| .|.|.| .|| | || .. ||||| .. . .. .| .|||| . . ||..|.||. . |||...| . || ||
sakrnss..lrknryrdilatddtrvkllrviter..dyinadyvvfpdeeadlkyilaqGplsatvddfwtlvaeqdvrvivmvaklqedGrdkcapyw
PDKTE--TYGGVTVTLHQSEVFAGYENCTFI-LSKEKRSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRK
|. . | | . |.. ... . | || || || | |||.||| . |. .
psvvqerlkagdvvveflsstsdefdrviltelqliyrsesrvvrhvqflswpdhGvpsdledlvrfqaq
|
|||||||||
subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 151-400 | 5.9e-118 | 387.6 | In-house | 4-245 (250) | alignment | ||
Range on Protein: 151-400
Range on HMM: 4-245/250.0
ARKPAnkNKNKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGYDGTpRSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTkCHKYWP-
|.||. ||.|||||.|.|.|.||||||...||.. |||||||.||||.. ..|||.||||....|.|||||.|..|..|||||||. .|| .|.|||
akkpq..nkeknryadiialdssrvvLekekgdkesdyinasflhgyder.kafiatqgPlqatiedfWrmvleeksgtivmLtnLkesekt.yhqywPv
DKTETYGGVTVTLHQSEVFAGYENCTFILSKEKRSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRALNPR-DAGPVIVHCSVGVERTGAYIVIDAML
.|.|.||.|||.|...|.|| |. ...|||.|....|||||.||.||||||||..|||||....||.| ... ...||||.|| || |.||.|.|||.|
ekaekyGdvtvsllskeefadytkrklklskakkaderivrqlhfvvWPdkgvPevatavLellkkvqasqqqagnaPvivqCsaGvgrsGafiaidavl
EQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTCgnteiqS
|..||...||........||.|||.|...|||.|.....|.||.. .
erlkkekvvdvfkvikvlrkdrphavesleqyvfvyeiilkalds......v
|
|||||||||
subfamily_PTPN6_pd | Subfamily PTPN6 | 151-390 | 4.5e-72 | 237.6 | In-house | 49-296 (306) | alignment | ||
Range on Protein: 151-390
Range on HMM: 49-296/306.0
ARKPanKNKNKNRYANIVAYDHSRVVLErVNGDEDLDYINASFIH-GYDGTPRSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWP
..|| .||.|||| ||. .||.||.|. .. . |||||..|. |. .|.||.|| |. . ||||||..||. |||.|. | .| || .|||
gakp..enkeknryknilPfDhtrvilk.epsvpgsdyinanyikkevkgsdksyiatqgclettvsdFWrmvwqensrvivmttkevErgkekCarYWP
DKT--ETYGGVTVTLHQSEVFAGYENCTFILS-KEKRSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRA----LNPRDAGPVIVHCSVGVERTGAYI
|.. |.|| ..|| ... | |. .. .| |.| . .| |.|.||..|||.|||. |||.| ..|.. |. ..|||..|||| |. |||..|
deeekeeyGkisvtnvseksladYilRelsvskkkkkkeerevfqyhfksWPdhgvpkdpgavLdfledvnrkqeeleeaeagpivvhCsaGiGRtGtfi
VIDAMLEQAKKS---RTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEA
|||..|.. .|. .||.. .|..| .|||..|| |.. |. .
viDillkliekkgldadidiqklvksvreqrsglvqteqqykfvykaikky
|
|||||||||
subfamily_Sponge-PTP5_pd | Subfamily Sponge-PTP5 | 151-399 | 1.3e-51 | 170.2 | In-house | 26-274 (283) | alignment | ||
Range on Protein: 151-399
Range on HMM: 26-274/283.0
ARKPANKNKNKNRYANIVAYDHSRVVLERVNGdedlDYINASFIH--GYDGTPRSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYW
. |..||.|||. .||..| || |. . |||||.|| . . .|..|.|| . ||.||.... .|||||.| .. || .||
diasadenkrknrnqeivpadqwrvelksesr....dyinavfipvsksykqdkkyiiaqsPldrtvvdfWkmvfdekitaivmltklqedlrikCsqyW
PDK-TETYGGVTVTLHQSEVFAGYENCTFILSKEKRSG-SRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRALNPRDAGPVIVHCSVGVERTGAYIVIDA
| . .| || ||||.. . ..| .. . . .. . . | . | ... | . . . ||..|||| |. ||...| . |
PkrGsedyGeftvtlrkettsnsfiikelllrvnssakstlllahyqvidWleygeqaiinslvkfnkvislqteskkgPivvhCstgiGrtavfiaasa
MLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTCGNTEIQ
...|. . ||. . . .|..|. .|||..|| ..| .||| ||.|.|
svkdaltesvvdvfavvkimreqrmmavqtldqyklvhelvleqalcgdtqia
|
|||||||||
subfamily_Cele-PTP-16_pd | Subfamily Cele-PTP-16 | 152-391 | 1.2e-14 | 48.6 | In-house | 41-279 (303) | alignment | ||
Range on Protein: 152-391
Range on HMM: 41-279/303.0
RKPANKNKNKNRYANIVAYDHSRVVLErvngdeDLDYINASFIHgYDgTPRSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPDK
.. || .|||..... |||.| | | || ||... | . . | .| ||. . ||.|. ||. . ...| .| . .| .
knqfvknmdknrfvdvicldhskvkls......dssyihasyle.ld.sskkailtqlplshtaadfwqmiieqkvkcvlllltdseydklggdsvfprn
TETYG----GVT-VTLHQSEVFAGYENCtfILSKEKRSGSRIVRQFHFTVWPDKGVPQY-----ATAVLAFRRKVRALNprDAGPVIVHCSVGVERTGAY
. . ... |. |. .|| . . .. |. || . .| . . .| |. | . |. |.|..
qdflkfeersirvgefkrvelgdgwvlk..vlsvsngdyksflhvhhykawphnsipsdgspkfvkqiwqlqsvlrkys..dstptvymslsgcgragtf
IVID-AMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEAL
... | | .. ..|. . | .|. | | || |.|.... . | .
alfetahlslhseqasldlvkclenvrngrlhavqnlsqfsvvytllaehv
|
|||||||||
subfamily_Cele-PTP-14_pd | Subfamily Cele-PTP-14 | 153-399 | 1.9e-32 | 107.1 | In-house | 47-297 (310) | alignment | ||
Range on Protein: 153-399
Range on HMM: 47-297/310.0
KPANKNKNKNRYANIVAYDHSRVVLErVNGDEDLDYINASFIHGyDGTPRSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPD--
. .|. ||||...| | ||| |. .. ||| | ... . .|| ||||| . ||||.... ..||..| . . . || |||
eaykkymhknrysdvvcldtsrvklk.idksryedyihanyvkt.nylrstficsqgplqhtiidfwrmifqeraesilllckvgeegrpkcvgywpslg
KTETYGGVTVTlHQSEVFAGYENC----TFILS----KEKRSGSR--IVRQFHFTVWPDKGVPQYATAVLAFrrkvRALNPRDAGPVIVHCSVGVERTGA
||||| . || || .| | ||. |. . . | .. |||.|||. . | | ||..|||| |..|...
vtetygcirvt.nlsesseefeicnlavtfvpdnvpvdeqpanlkelrvslikwpnwpdrgvpdekchtvpq....rllaqvrhgpcvvhcsagkdrlyv
YIVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLeALTCGNTEIQ
. .. ...... ||. . ..|.| .||. || .|. . ... |.||.
vvalklkidkldrglkvdaeevktellksraiciqtelqyliidrvri.ifargeteva
|
|||||||||
subfamily_PTPN13_pd | Subfamily PTPN13 | 154-392 | 8.2e-63 | 207.2 | In-house | 33-270 (273) | alignment | ||
Range on Protein: 154-392
Range on HMM: 33-270/273.0
PANKNKNKNRYANIVAYDHSRVVLERVNGdedldYINASFIHGYDGTP-RSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPDKT
..||.|||| |.. ||..|| |. | |||||.|. | ..||.||||| . . ||.|||||... |.|.|. . .| |||.|||...
kkkenkdknryrnvlPydetrvklgdegg.....yinaslikvpvgkdeyeyiacqGPlPetvkdfwqmvweqkaeviamvtlekekgkvkchrywPesk
E----TYGGVTVTLHQSEVFAGYENCTFILSKEKRSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRALNPrDAGPVIVHCSVGVERTGAYIVIDAML
. .. ..|.| . . |. .. ... . . || | ...|. ||| |||. |. .| | ..|| |. ||||..|||| |. |.|..|.||..|
nkklkvsnrlevellkvqkldgfvvralavkdsesgesrevahlnfvkwPdhgvPssaaellqfvaevrrlqt.dagPivvhcsaGiGrsGtlitidvvl
EQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALT
. .. . .|... . .|. | .||||.|| |.. |.||.|.
glierdkefdvkeivrklreqrqgvvqtkdqyifvykailevlk
|
|||||||||
subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 154-389 | 1.7e-37 | 123.9 | In-house | 29-257 (267) | alignment | ||
Range on Protein: 154-389
Range on HMM: 29-257/267.0
PANKNKNKNRYANIVAYDHSRVVLERVNGDedldYINASFIHGYDgTPRSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNlVGLNktKCHKYWPDK--
|.||...||. . . ||..||.| . . |||||...|| | . ||. |.|| . |. .. .|. ||.||. |. . . ...|| |
iaeknqernrlddnlpyddtrvilrtkeee....yinasyvegyk.tknafivtqdplkntitdfltvihdqkvpvivlltk.vftd..nirlfwPPkmg
-TETYGGVTVTLHQSEVFAGYENCTFILSKeKRSGSRIVRQFHFTVWPDKG-VPQYATAVLAFRRKVRALNprDAGPVIVHCSVGVERTGAYIVIDAMLE
.. | .|| . |. |. | | .. | ... | . | ... | . | |..|.|| || |.|...|||..||
qakkyqdltvehslekeendyqiitlelkf.knesahnvtlyyykkwnintnnkpylkplfgilaknqlen..gnrPlvvacsdGvGrsGtflvidsqle
QAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLE
.||. ..|| ..| ||. |. .|.|||.| .|| . |
raktegvsdifdflrkirsqriglvdtkeryiyihellae
|
|||||||||
subfamily_PTPRA_pd | Subfamily PTPRA | 155-422 | 5.3e-88 | 290.1 | In-house | 55-326 (330) | alignment | ||
Range on Protein: 155-422
Range on HMM: 55-326/330.0
ANKNKNKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGYDGTpRSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPDK-TE
..||.|||. ||. ||.|||.| ..| |. ||||||||.|| .|||.|||. . | ||||.|||.|..|||||.| ...||..||||. .
keenkeknrvvnilPydfsrvilsvkeGveesdyinasfidGykek.dkfiaaqGPkeetvedfwrmiweqksativmltelkerkeekcaqywPdeGlv
TYGGVTVTLHQSEVFAGYENCTFILS----KEKRSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRALNPRDAGPVIVHCSVGVERTGAYIVIDAMLE
||| ..|......| | |.. . .. ||.||||||| ||| ||| . .| . .||..||.. |||..|||| || |||..||.||.||
tyGnirvevedetvlvdytvrkflvqqlpdatrekksrlvrqfhftswPdvGvPfepiGmlkllkkvkklnqqsagpivvhcsaGvGrtGtfivldavle
QAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTCGNTEIQSEKYNQAMQKLASVNGKFPMTGY
. | | ||. . . .|. ||.||||.||| ||. ..|| |.||.. .. .||| . .. .|
rvkaerkvdvfefvkrlrlqrpqmvqtdeqyefiykvlleyylygdteldvsslekhlqklynkitgtdkigl
|
|||||||||
subfamily_PTPN14_pd | Subfamily PTPN14 | 155-391 | 3.5e-50 | 165.7 | In-house | 46-296 (300) | alignment | ||
Range on Protein: 155-391
Range on HMM: 46-296/300.0
ANKNKNKNRYANIVAYDHSRVVLERVNgDEDLDYINASFIHGY-DGTPRSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPDK--
..|..|||. ... |...|| | . ... .||||| |. |. ||.|..||||. . . ||.|||||. | |||||. |.|..||.|..
lpenaeknrfkdvlPyednrvelsptk.enstgyinassikvsvggkersyivaqgPleltvqdfWqmvWeqgvqlivmlteeeedgkeksfkyfPkles
---TETYGGVTVTLHQSEVFAGYENCTFILSKEKRSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRALNPR---------DAGPVIVHCSVGVERTG
| ..| || . || . .. | . | | . .| |||.|||. . | . ..|... . ||.|||| || |||
kkktvefgkfkvttkfsedsdsvittglklkhlpskeertvwhlqytDWpdhgvPeDvkgflsyLeevqsvrrktnseveskeskPPvlvhCsaGvGrtG
AYIVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEAL
|. | ... .. ...||.. | .|. | ..||| || |....... |
vlilsdlliatlehneeidikkvlarLreqrmllvqtlaqYkfvYkvlikyl
|
|||||||||
subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 155-389 | 3.8e-40 | 132.4 | In-house | 51-281 (290) | alignment | ||
Range on Protein: 155-389
Range on HMM: 51-281/290.0
A--NKNKNKNRYANIVAYDHSRVVLErvNGdEDLDYINASFIHGydgTPRSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPDKT
| . .|||| ..| | .||.|. .| | ||. | ...| . || .||.| . .|||| ... |||| .|. |.||..|.|.|
fdkntefkknrykdvvcndktrvilk..dG.ydGdyvhanyvkG...lkamfiltqGalkdtvidiwrmvlqekvaaivmlceliedGkakceqyypeke
---ETYGGVTVTLHQSEVFAGYENCTFILSKEKRSG-SRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRALnprdAGPVIVHCSVGVERTGAYIVIDAML
|.| .||. ... . ..| || . ... .. |||| |.. . |.| | .| . .|||.|||| |. |||... |.. |
GevltfGeitvlcseeddkdaniikktlsvrdkdsGkehklkhlkikswpdksvalstlallrtlrilrka....sGpvvvhcsaGiGrtGtfvaievgl
EQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLE
. . . .|. . |.|. | || || . ..|.
qilldGkeldlldlvralrnsrlnsvqvdiqylalveilld
|
|||||||||
subfamily_ptpA1_pd | Subfamily ptpA1 | 155-349 | 1.7e-31 | 104.4 | In-house | 44-254 (418) | alignment | ||
Range on Protein: 155-349
Range on HMM: 44-254/418.0
ANKNKNKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGydGTPRSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPDKTET
..| .||||.||. .|.|| |.... | ||||| .| | |. ||..||||| . |||||||. . ||||. . || .|||..
kkhntsknrytnilpvnhtrvqlkkiqdkegsdyinanyidg..aypkqfictqgplpntiadfwrmvwenrcriivmlsresencrikcdrywpeqigg
yGGVTVTLHQSEVFAGYE--NCTFILSKEK-----------RSGSRIVRQFHFTVWPDKGVPQYATAVLAF-----RRKVRALNPRD-AGPVIVHCSVGV
... ||| | | |. .| . |... |||. .|... . . |. . . | |.||||| ||
.eqfsiygngnevfgtysvelveviqdpereiitrnirltfegetrditqyqyegwpdhnipdhtqpfrqllhsitnrqnqiipssdrnvpiivhcsagv
ERTGAYIVIDAMLE
|||.. |..
grtgtfctavimmk
|
|||||||||
subfamily_Cele-PTP-17_pd | Subfamily Cele-PTP-17 | 155-231 | 2.8e-09 | 31.0 | In-house | 34-114 (347) | alignment | ||
Range on Protein: 155-231
Range on HMM: 34-114/347.0
ANKNKNKNRYANIVAYDHSRVVLERV-----NGDEDLDYINASFIHgYDGTPRSFIASQGPLPPAFEGFWRMVWEQNSQSIV
.|. .||| . | .|||| . |. ||||| |. .| . . .| .| ||| . ||.|| . .|
wekslsknrskdvklidatrvvlspeksknsraddvetyinashik.fdnaskeyiltqyplpdtvrdfwkmvsvtkvtqvv
|
|||||||||
subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 156-389 | 1.5e-95 | 313.9 | In-house | 6-239 (239) | alignment | ||
Range on Protein: 156-389
Range on HMM: 6-239/239.0
NKNKNKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGYDGTPRSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPDKTETY
|| ||||||||.|||||||||... | ||||||... |||.|...||.|| . .. ||||.|.. ||||| |. | |||.|||| | |
rvnkaknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpdstsky
GGVTVTLHQSEVFAGYENCTFILSKEKRSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRALNPRDAGPVIVHCSVGVERTGAYIVIDAMLEQAKKSR
. |||...|||| | ||..|. .. | | |.|||||||||||||||||| .|||. . | | ..||| || ||||..|||||| |||| .
cnlrvtlrktevfadyiirtfvmsqvgqteeryvyqyhftvwpdkgvpqyatavlglrrkitkdslpgarpwvihcsagvgrtgaflvidamlrqakkqk
TVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLE
|||| ||. |||. ||||||| ||| ||| ||||
tvdifnyvkairedrphmvqtseqyvfihlavle
|
|||||||||
subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 156-410 | 5e-75 | 247.6 | In-house | 23-274 (284) | alignment | ||
Range on Protein: 156-410
Range on HMM: 23-274/284.0
NKNKNKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGYDgTPRSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTnlvglnKTKCHKYWPDKT-ET
..||.|||. .|.|.|...| |||. | | |||||||| || . .||.||||. . . ||||.||.|. .||.|| | || .||| |. ..
dqnkdknrighilafdknvvklerliGeefsdyinasfitGyq.rkdkyiatqGPldntladfWrmiweyncstivllt......kdkcsqywplkivik
YGGVTVTLHQSEVFAGYENCTFILSK-EKRSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRALNPRDAG--PVIVHCSVGVERTGAYIVIDAMLEQA
.. | .. | . | . ||. | . | .||||| |||.|||.|.. .... .||| |. . . ...|||| || |||.|||.|..|..
eerfkvkvdsveeseeyvvrdielsedgkekdirkirqfhflgwpdvgvpdypsdlmrlvkkvrhltskenhranivvhcsagvgrtgvyivldvlldrm
KKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTCGNTEIQSEKYNQAMQKL
|. . ||. |.. .|. |...|| || ||.||.|| |.... . ...|
keekqvdvynfvrdlrqqrntlvqdlvqykfiysalleehlfghsdvalpdfpayleel
|
|||||||||
subfamily_PTPN5_RR_pd | Subfamily PTPN5_RR | 156-389 | 4.2e-67 | 221.1 | In-house | 26-266 (274) | alignment | ||
Range on Protein: 156-389
Range on HMM: 26-266/274.0
NKNKNKNRYANIVAYDHSRVVLERVNGDE-DLDYINASFIHGYDGTPRSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPDKTET
....|||| .|. ..|||.||. .... |..|||| .|.|||.. . ..| ||||| . . ||||......| |||||.| |..||..|.||....
fgsqtknryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntvadfWrmiyqeevqvivmltklkeaneqkCavyfPdaedy
-----YGGVTVTLHQSEVFAGYENCTFILSKEKRsgSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRALNPR---DAGPVIVHCSVGVERTGAYIVIDA
||.| .. .. .|. ...|.. .| .| | . .| |||. .|. |...| . ..|. . . ..||.|||| |. |||..| |.
eiserygdveikvekiverndysvrklvlkyler..ersvkhywytdWPdhksPddantlldlvleveesreeenaklapvvvhCsaGiGrtGcfiaisi
MLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLE
. | ... .||. . .| .| ||||.||| .|| |. .
avrqlreeivvdvlkivcnlrldrGGmvqtseqyelihralcl
|
|||||||||
subfamily_CG7180_pd | Subfamily CG7180 | 156-395 | 6.9e-63 | 207.0 | In-house | 40-294 (296) | alignment | ||
Range on Protein: 156-395
Range on HMM: 40-294/296.0
NKNKNKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGYDgTPRSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKtKCHKYWPDK-TET
..|..|||. ..| ||. |||||...|.|. |||||... .. .. .| ..| . . |||.|........|.||. .| ....||| | |
kenreknrdvkvvPyDynRvvLekldGeeksdYinavyvdsfl.kkkeyivteapkketvdefWrlvydeeisavvvLtktfdfak.mypsywpnkskeq
YGGVTVTLHQSEVFAGYENCTFILSKE----------KRSGSRIVRQFHFTVWPD-KGVPQYATAVLAFRRKVRALNPRD-----AGPVIVHCSVGVERT
|| . | . ... .| . || | |. |||..|..|.|. . || ..|.. .||.|| . . |||.|..| |. |.
ygeifveiveekqyanlkirtfkltkkivalteqekqvkaetRivklfqlteWeledkvPlstnalielrrrvrlwrekvdedpeegPvvvvssdGasRs
GAYIVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTCGN
|.|. ||| ||...| ||. ... .|..||..|...|.| .| .|||. |.
GvylaidanlelvekeeevdvFeavktlrrsRpqLvenveeYkyiYdvlleavlcnk
|
|||||||||
subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 156-389 | 1.2e-61 | 203.1 | In-house | 18-262 (270) | alignment | ||
Range on Protein: 156-389
Range on HMM: 18-262/270.0
NKNKNKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGYDGTPRSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPDKTET-
..|. ||||.|. ..||.||... |. |||| ...|.|| ....||..|||| . . ||||.||.....|||.|.|. ...|| .||| ....
argkklnRyadiLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpaepkek
----YGGVTVTLHQSEVFAGYENCTFILSkEKRSGSRIVrQFHFTVWPDKGVPQYAT------AVLAFRRKVRALNPRD--AGPVIVHCSVGVERTGAYI
.| ..|. ..| || | || . |.| |... |||.|||. . .|. |.||. . . |.|..|||| ||.||| |
vkledgkikvlalseekeegyiltrlrle.ekgeerrlv.HfwyntWpdhgvpreedsslstdqllkmlravrrsekeldkaePllvHcsaGvgRtGtli
VIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLE
..| ... .... ||. . . ..||.|. .||. ||| |.. ||.|
alDiavrlLeetkkvdvlaiieelRkdRmalvqhpeqyeflykavve
|
|||||||||
subfamily_Cele-PTP-11_pd | Subfamily Cele-PTP-11 | 156-397 | 7.7e-30 | 98.7 | In-house | 41-282 (312) | alignment | ||
Range on Protein: 156-397
Range on HMM: 41-282/312.0
NKNKNKNRYANIVAYDHSRVVLervNGDEDLdYINASFIHGYdGTPRSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPDKTety
| |. ||| || .| | | |||.. || | |.. | |...|||| . ||... | ||..|. .| || || |
lkfkdlnrypniqcwdrgrftl...agdenf.yihanfvkic.tkperfvctqgplentcthfwqlalslgstsiillcgfvedgsekcakyisdiv...
GGvtVTLHQSEVFAgyENCTFIL----SKEKRS-----------GS-RIVRQFHFTVWPDKGVPQYATAVLafrRKVRALNpRDAGPVIVHCSVGVERTG
| | | . |.. | || | ||.| . | . .. .. |||.|.|. . | | . |.. .| ||| ||| || |||
gf..vdledhrvyt..eycteieiggkskdkithrvlkvvvkatgqesklnhyqwaswpdhgmpdscdtal...rllsavk.kdkkpviahcsagvgrtg
AYIVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTCGNTE
. ..|..|. .. | .... .. .|| | |.. || . .||| | .
tlaliesmiaalrhprkqnvkdsfvllrkdrarsvrvfpqyvyalrcvleflyskgly
|
|||||||||
subfamily_Cele-PTP-15_pd | Subfamily Cele-PTP-15 | 156-391 | 5.7e-29 | 96.0 | In-house | 33-270 (285) | alignment | ||
Range on Protein: 156-391
Range on HMM: 33-270/285.0
NKNKNKNRYANIVAYDHSRVVLErvngDEDLDYINASFIHGYDGTPRSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPDKTE--
. | . ||||.. . . .||||. . | ||| ||... ..|..||||| .. ||.|..... ..|| |. || |.|.|
eanpdlnryadvrcieetrvvlk....nhdrdyihaswmrmpgkdqstyittqgplpetlsdfwhmiyqekiayvlmlctlfeggvekcalyypeklgev
-TYGGVTVT--LHQSEVFAG--YENCTFILSKEKRSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRALNPRDAgPVIVHCSVGVERTGAYIVIDAML
.| .| . | || ... | | ... | . . . |||. |. | .. . . |. .||.. |. |||| || || ... ||
vkfgkyeitlteckeeaiagtilnaltvintedasseplymnhvqvpwwpdqlapedarpmielykwvkkvnpkek.picvhcsagvgrtatfvgidyat
EQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEAL
. . ... . . .| | . ||.. |. |.. ..| .
irimenpniemldivremramrfqavqshmqflflyvvlmeyf
|
|||||||||
subfamily_egg_pd | Subfamily egg | 156-388 | 4.5e-23 | 76.4 | In-house | 38-267 (307) | alignment | ||
Range on Protein: 156-388
Range on HMM: 38-267/307.0
NKNKNKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGYDgTPRSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLnkTKCHKYWPDKtETY
. |..| | . | ||| || .| |.| | ..| || .| || . . |||||.... | ||||| . .|. ||| |.
dnnlekarskrvhckdssrvklelrrGqylddfihanrvkGkp.llnefilaqaplkntvddfwrmvfqeevqyivmltsrkes..erceyywpka.esd
GGVT--VTLHqSEVFAGYE--NCTFILSKEKRSGSRiVRQFHFTVWpdKGVPQYATAVLAFRRKVRALNpRDAGPVIVHCSVGVERTGAYIVIDAMLEQA
|| .|. | . .. . | ..| | |. . . | .| .... | | .| | . . ||.|.. || .... . |. | .
slvtvpGslr.ienlkvdskadplfrvtklklvGgd.deerflehw..qgdvnnssdvysplrvlrklr.nlskpvvvqdilGvskaatlvaieiallsl
KKSRT--VDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVL
. . ... .|..|. |.. .| |.. ||
lrGpitkslvlravvflrlrrrlsvesvllylfvyrlvl
|
|||||||||
subfamily_Cele-PTP-4_pd | Subfamily Cele-PTP-4 | 156-388 | 2.1e-20 | 67.3 | In-house | 49-282 (302) | alignment | ||
Range on Protein: 156-388
Range on HMM: 49-282/302.0
NKNKNKNRYANIVAYDHSRVVLERvngdEDLDYINASFIHGYDGTpRSFIASQGPLPP---AFEGFWRMVWEQNSQSIVMLTNLVGLNKtKCHKYWPDKT
|| .||. .. ..|. .| || | .|.||| .. . | || | .| | . | |||||.... .|.|.| |.| ....| |.
kknlkknqsedvpildsnlvklea....epdsyvnaskvevPelt.rsiilaQlpkvdsedsveeFWrmvfqekivsvvilvgeeelkk.tlselfpkks
ET---YGGVTVTLHQSEVFAGYE-NCTFILSKEKRSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRALNPRDAGPVIVHCSVGVERTGAYIVIDAML
.. || . | . | . . . . . | | | .. ..| |..| ||. ... . || |.. .... |. | || .. . .
gdykeygkmfvNnrkVekaeeektryviEvlPegcsnsvlanvyvltnWkqkkvpvkyaeliktaakvfakkikadentvivSknGaGRagafltlavav
EQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVL
|. .|. . | . ...||. ||..|.. .|| ... |.|
eklqkgkepnikeivksiRsqRpravdslkQyvslyiall
|
|||||||||
subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 157-390 | 4.8e-96 | 315.5 | In-house | 6-239 (239) | alignment | ||
Range on Protein: 157-390
Range on HMM: 6-239/239.0
KNKNKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGYDGTPRSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPDKTETYG
|| ||||||||.|||||||||... | ||||||... |||.|...||.|| . .. ||||.|.. ||||| |. | |||.|||| | |
vnkaknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpdstskyc
GVTVTLHQSEVFAGYENCTFILSKEKRSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRALNPRDAGPVIVHCSVGVERTGAYIVIDAMLEQAKKSRT
. |||...|||| | ||..|. .. | | |.|||||||||||||||||| .|||. . | | ..||| || ||||..|||||| |||| .|
nlrvtlrktevfadyiirtfvmsqvgqteeryvyqyhftvwpdkgvpqyatavlglrrkitkdslpgarpwvihcsagvgrtgaflvidamlrqakkqkt
VDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEA
||| ||. |||. ||||||| ||| ||| |||||
vdifnyvkairedrphmvqtseqyvfihlavlea
|
|||||||||
subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 157-389 | 6.3e-86 | 282.5 | In-house | 2-237 (237) | alignment | ||
Range on Protein: 157-389
Range on HMM: 2-237/237.0
KNKNKNRYANIVAYDHSRVVLERVNGDedLDYINASFIHGYDGTPRSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPD--KTET
.|| ||||.||||||||||||. .. |||||....|.||||...||.|||| .. . ||.|||... ||||| |. |. |||||||. . ..
enkiknrygnivaydhsrvvlkgagsg..sdyinatylkgfdgtpkkyiaaqgplesscddfwqmvwqekcsvivmltgliegnelkchkywpstdqpaa
YGGVTVTLHQSEVFAGYENCTFILSKE-KRSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRALNPR--DAGPVIVHCSVGVERTGAYIVIDAMLEQA
|| .||.|.. | |. | ...|||. . . |.. |..||.|||.||||...|.| ||... .| ..|| |.||| || ||| ..|||||| ||
ygvltvslkkkeefsdytvrslllskrltlkevrlihqyqftswpdrgvpqqtaallrfrkniinrsphvsesgpwiihcsagvgrtgiflvidamlrqa
KKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLE
|. . ||| ||. .| . ||...|||.|| ||| ..||
kekkvvdiynyvysieedrpyiiqtkdqyvfihqtile
|
|||||||||
0040439 | (Phosphotyrosine protein) phosphatases II | 157-391 | 4.1e-76 | 251.1 | In-house | 10-246 (249) | alignment | ||
Range on Protein: 157-391
Range on HMM: 10-246/249.0
KNKNKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGYDGTPRsFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWP-DKTETY
.||.|||| .|..||||||.|. ..| .. ||||||.|.||. ..| ||| ||||| ..| ||||.||.....|||||.|| |.. ||..||| ... .|
enkdknrypdilpydhsrvklsilpglflsdyinAsyidgyyikrr.fiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqywplggsley
GGVTVTLHQSEVFAGYENCTFILSKEKRSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRALNPR--DAGPVIVHCSVGVERTGAYIVIDAMLEQAKK
|..|||| . ||...| |. |.. . . || |.....| ||| |||.. .|.| ..|| . . . |||.|||| || |||..|... |||| .|
gdftvtllsvevkddytvrtleltnlydgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtfiaaylmleqlek
SRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEAL
..||. ... .|..||..||. ||| |.. |.|| |
elgvdleeavkllrsqRpgavqnpeqyrflyeallell
|
|||||||||
0042113 | (Phosphotyrosine protein) phosphatases II | 157-390 | 2.9e-75 | 248.1 | In-house | 8-242 (245) | alignment | ||
Range on Protein: 157-390
Range on HMM: 8-242/245.0
KNKNKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGYDGTPRsFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWP-DKTETY
.||.|||| .|..|||.||.| ..||.|.||||||...||. ||. |||.||||| .| ||||.||.....|||||... |.. ||..||| . . ||
enkdknrysdilpydhtrvklspdggdldsdyinasyvdgyritpk.fiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywplgeslty
GGVTVTLHQSEVFAGYENCTFILSKEKRSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRALNP-RDAGPVIVHCSVGVERTGAYIVIDAMLEQAKKS
|..|||| |....| |. ..... . || |...|.. ||| ||| . .| | . || . |||.|||| || |||..|... ||||..|
gdftvtllseehlddytvrtlevtnlgddesrevihyhylpwpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylmleqleke
RTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEA
..|.. . . .|..||..||| .|| |.. |.||
lgvsleeavkelrsqRpgavqtpsqyrflyeallel
|
|||||||||
0045098 | (Phosphotyrosine protein) phosphatases II | 157-394 | 3.4e-74 | 245.0 | In-house | 32-275 (278) | alignment | ||
Range on Protein: 157-394
Range on HMM: 32-275/278.0
KNKNKNRYANIVAYDHSRVVlervngdedlDYINASFIHGYdgtPRSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPDKT-ETY
.|..|||| .|..||||||. ||||||.|.|| |. ||| ||||| .. ||||.||.....|||||.|| |.. ||..|||.. .||
gnldknRykdilpydhsrVk..........dYINAsyidgy...pkkfIatqgPlpstvadfwrmlwelgitvivmltelvelgrekcaqywpeggslty
GGVTVTLHQSEVFAGYENCTFILSKE----KRSGSRIVRQFHFTVWPDKGVPQYA--TAVLAFRRKVRALNPR-------------DAGPVIVHCSVGVE
|..|||| . ||. | .|... . || |...|.. ||| ||| . . .| . . .|. . . . |||.|||| ||
gdftvtllseevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllsslllldsggpvlVHCsaGvg
RTGAYIVIDAMLEQAkkSRTVDIRNYLIAIRKHRPH-MVQTKEQYSFIHSAVLEALTCG
|||...... |||. ..||. ... .|..||. .||..||| |.. ..|| | .|
RtGtlvaaylmlell..eggvdlleavkelrsqRpglavqnleqyrflyefllelllrg
|
|||||||||
0037934 | (Phosphotyrosine protein) phosphatases II | 157-389 | 3.2e-69 | 228.5 | In-house | 9-240 (243) | alignment | ||
Range on Protein: 157-389
Range on HMM: 9-240/243.0
KNKNKNRYANIVAYDHSRVVLervngdEDLDYINASFIHGYDgtpRsFIASQGPLPPAFEG----FWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPDKT
|..|||| .|..||||||.| |. |||||..| ... | .||.||||| .| ||||.||.....|||||.|| |.. ||..|||...
enlsknrysdilpydhsrvkl......egsdyinanliyvtp...r.liatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqywpgev
eTYGGVTVTLHQSEVFAGYENCTFILSKEK-RSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRAL--------NPRDAGPVIVHCSVGVERTGAYIV
|||..|||| ..|....| |. |. . .| |...|.. ||| |||. . .|.| ..||. . . |||.|||| || |||..|.
.tygdftvtllseehlddytvrtlllenldlddltrlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgRtGtlia
IDAMLEQAkksrTVDIRNYLIAIRKHRPH-MVQTKEQYSFIHSAVLE
.. ||.. .||. ... .|..||. .||| .|| |.. |.||
aylmllll....gvdleeavkllreqRpgkavqtpsqyrflyealle
|
|||||||||
subfamily_Sponge-PTP6_pd | Subfamily Sponge-PTP6 | 157-405 | 2.7e-60 | 199.1 | In-house | 47-293 (439) | alignment | ||
Range on Protein: 157-405
Range on HMM: 47-293/439.0
KNKNKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGYDgTPRSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKtkchkYWPDKTETY-
.. |||| ...|.||.||.|. . | |||| .|.|| ... .||.||| . . |||.|.|... |||||||| | ||| ..|..
ydqtknrykdvgafdhtrvtlqeipgvphshyinanyikGyy.ddklyiatqgpkkettddfwrlviekktvtivmltnlvesyk.....ywpsdaevcy
GGVTVTLHQSEVFAGYENCTFILSKEKR--SGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRALNP-RDAGPVIVHCSVGVERTGAYIVIDAMLEQAK
| ..| . . | | . .|. | | |||.. |||| || |. || | | . . | .. |||.|||| || |||. | .| ||| |
gdiavrvdrnielpnyvirgfkvfnerdttekertvlqfhyiawpdknvpaqashvldflrainsandkeeygpvvvhcsagvGrtGtiialdialeqlk
KSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTCGNTEIQSEKYNQ
|||. . .||.| .|||. || ||. |||| . |.. .. .....
lenkvdikgivkvlrkqrkqmvqalcqyvfiynavledivyGdiavtidefkk
|
|||||||||
0049772 | (Phosphotyrosine protein) phosphatases II | 157-392 | 6.1e-39 | 130.0 | In-house | 45-281 (314) | alignment | ||
Range on Protein: 157-392
Range on HMM: 45-281/314.0
KNKNKNRYANIVAYDhSRVVLERVNGDeDLDYINASFIHGYdgtpRSFIASQGPLPPAFEGF----------WRMV--WEQNSQSIVM------------
.|..|||| .|. .| .||.| ..... . ||||||...|. ..|||.||||. .. | |||| ...|. |||
lnrdknryldilpad.nrvilpglpvs.gsdyinasyvdgf....lkfIatqgpleitvvdfreepvlyyngwrmvlrgdlnvrdivmsrdevladelsr
---------LTNLVGLNKTKCHKYWPDKTetyggvtvtlhqsevfagyenctfilSKE--KRSGSRIVRQFHFTVWPDKGVPqYATAVLAFRRKVRALnp
|..| |.. . ..... . . .| . ... . .|| ..| ...| . ....
LdaAlgKtpllildgngneptaadlellk..........................eelydpelferlgikylripvpDgsap.lledfdeflefieea..
RDAGPVIVHCSVGVERTGAYIVIDAMLEQAKksrtVDIRNYLIAIRKHRP-----HMVQTKEQYSFIHSAVLEALT
.. |||.|||. |. ||| ..|.. .. . . |... | .|. || ..... ||| ||. |.||.|
dkggpvlvHCkaGkgRtgtfvvaaylmkllg....vsleealedvrlkRpinpnpgfieqleqyefilealleylk
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 157-317 | 1.4e-33 | 110.9 | In-house | 27-191 (319) | alignment | ||
Range on Protein: 157-317
Range on HMM: 27-191/319.0
KNKNKNRYANIVAYDHSRVVLERVNGDEDLDYINASFIHGYDGTPRSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPD-----K
|.|.|..|.| ..||||.|. |. |..||.. ||| .| |.||.| .| . |||.||||.|. || ||.| | .| .|.|
tskdksrvinvvPlPetrvvlqrigdddkdeyldasyvrGyddapnsyiaaqvsledsssdfwrtvweqqsrvivqltdlselGikvcaeylPtketldn
TETYGGVTVTLHQSEVFAGYENCTFILSKEKRSGSRIVRQFHFtVWPDKGVPQYATAVLAFRRKVR
|..|| . ||| . || | |..| . ... || . . . |.. .|| .|..| .||
tslyGdilvtlkgrevkdryaistlllkrvdkeesrelthywy.kwleaevPaeeaaliamllevr
|
|||||||||
subfamily_Cele-PTP-13_pd | Subfamily Cele-PTP-13 | 157-389 | 9.6e-33 | 108.0 | In-house | 36-267 (281) | alignment | ||
Range on Protein: 157-389
Range on HMM: 36-267/281.0
KNKNKNRYANIVAYDHSRVVLER-VNGDEDLDYINASFIHGyDGTPRSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPDKTE--
|..||||.|| . | ||| |. . . ||| | .|. | .| .||| . ||||.|..|. .|||| ... |. || .|.| ..
vnnkknrylnipcldisrvqlkvkmpnknstdyihanyirs.pflkrgyiltqgpkketradfwrmiwqenttaivmlcqfletnrekcaeyfprnahcc
-TYGGVTVTLHQSEVFAGYENCTFILSKEkrSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRAlnpRDAgPVIVHCSVGVERTGAYIVIDAMLEQAK
. ..|. .| | . || | .|.. .. . ||| ||. . .| ||.|| | . | ..||| || |.|. . .. |. .
lqfdklsvsyedstvnkslvttrlnlsye..getrlithwlwkewpdwqvpessevmlkilrkira...rst.ppvihcsagvgrsgtlmaveialqsih
KSRTV-DIRNYLIAIRK-HRPHMVQTKEQYSFIHSAVLE
|. ||.. . .| | ||| .|| .| .|.
shftlpdikqivshlrvtgraasvqtlqqymliwkvlld
|
|||||||||
subfamily_Cele-PTP-8_pd | Subfamily Cele-PTP-8 | 157-399 | 2.6e-30 | 100.5 | In-house | 42-279 (288) | alignment | ||
Range on Protein: 157-399
Range on HMM: 42-279/288.0
KNKNKNRYANIVAYDHSRVVLErvngdEDLDYINASFIHGYDGTPRSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPDKTETY-
.| ..|| |. | .|| |. .| |. |. . .| .| .| || . | .|.|. |.. . ||||..|. . | | .|.| |
anptrdryenlprcditrvkls.....ddpdfyiaanvvssakykrrlicaqaPlngtieelWkmllesdveyivmlcellekGkeksaeyfPsklGeka
--G-GVTVTLHQSEVFAGYENCTFILSKEKRSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRALNprdaGPVIVHCSVGVERTGAYIVIDAMLEQAK
| ||. .. . . . . ... . ||.. |. |.|.|||. . | . ...|. |..||.| || |||. |.| .||...
rigrlctvvkkkradidklvkvsllriskegeekvivkilhlleWdddgvPenylsplrllevlkslq....kPivvhssaGvGrtgtlililialeslr
KSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTCGNTEIQ
. . ||. | |..| . .||. || ..| ||| | . .
lddflgirsllaklreerfkaiqtemqylyvhrcvleelllkkykvl
|
|||||||||
subfamily_Cele-PTP-1_pd | Subfamily Cele-PTP-1 | 157-408 | 9.3e-18 | 59.4 | In-house | 18-277 (290) | alignment | ||
Range on Protein: 157-408
Range on HMM: 18-277/290.0
KNKNKNRYANIVAyDHSRVVLERVNGDEDLDYINASFIHGYDGTprSFIASQGPLPPA-------FEGFWRMVWEQNSQSIVMLTNLVGLNKT----KCH
|.. ..|... .. ..||||. ||| |... .| .|..| |. | || |. . .....||| . .. |
khemdqRlevpLv.eatrvvLkgygkrfnddyiHAnrvtcpngl..rliltqsPqekitekrnStiekfwwmakqEkvkqvVmlcefeeksantslfaCa
KYWPDKTE---TYGGVTVTLHQSEVFAGYENCTFILSKEKRSGSRIvRQFHFTVWPDKGVPQYATAVLAFRRKVRalnpRDAGPVIVHCSVGVERTGAYI
|| |.. . ...|.|| . | . |. . .. ... . . | . |.. .|. .||. |||||| |. | |
kYvpesvgeelkfkgltvkCkskekeddvetRelvvkfddeeeftv.tHsllkgWnklnvqedtktllsliqkvk....asktpvivHcvdGiSrsAala
VIDAMLE-QAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAV-LEALTCGNTEIQSEKYNQAMQ
|. |..| | ... | |.||.| ..........|. .. | | ... ...|. ..|..
aiilgyQkiaetsgsvkledvlkalrkqralaitsalelafvdagivllaievldqfaeeetekkaka
|
|||||||||
subfamily_Sponge-PTP-2_pd | Subfamily Sponge-PTP-2 | 157-254 | 3.4e-10 | 33.1 | In-house | 26-90 (169) | alignment | ||
Range on Protein: 157-254
Range on HMM: 26-90/169.0
KNKNKNRYANIVAYDHSRVVLERVNGDEDLDYINAsfihgydgtprsfiasqgplppafegfwRMVWEQNSQSIVMLTNLVGLNktkchKYWPDKTET
|. ||| | .| | || |.|| | ||||| ||.|| |. ||.| . | .||.| .
cnetknrpagplapshtrvklqrvmedlgsdyina............................rmiwetnasvivvlgdtddkn.....nfwpekedy
|
|||||||||
subfamily_Sponge-PTP4_pd | Subfamily Sponge-PTP4 | 157-302 | 4e-10 | 33.7 | In-house | 95-235 (244) | alignment | ||
Range on Protein: 157-302
Range on HMM: 95-235/244.0
KNKNKNRYANIVAYDHSRVVLERvnGDEDLDYINASFIhGYDGTPRSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLvglnkTKCHKYWPDKT--ET
.| ||| . . .| .|| | . | ||||||. | | .| .| || . ||.|. |. . .|.| . . .|||| |
nnswknregaglpfdfnrvplsk..gsmgntyinasfv.gclgrtaeyiltqhpladtsmdfwkmmlerhvnvlvvlgsv.....eeedeywpdseplew
YG-GVTVTLHQSEVFAGYENCTFILSKEKRSGSRIVRQFHFTVWPDKGV
| .|||| . . | . . . . . | . || |
yeeditvtltdrdefknikasnleiesdmneshqaltmfqisnwpsdgt
|
|||||||||
subfamily_Sponge-PTP2_pd | Subfamily Sponge-PTP2 | 157-254 | 4.1e-10 | 32.7 | In-house | 25-89 (169) | alignment | ||
Range on Protein: 157-254
Range on HMM: 25-89/169.0
KNKNKNRYANIVAYDHSRVVLERVNGDEDLDYINAsfihgydgtprsfiasqgplppafegfwRMVWEQNSQSIVMLTNLVGLNktkchKYWPDKTET
|. ||| | .| | || |.|| | ||||| ||.|| |. ||.| . | .||.| .
cnetknrpagplapshtrvklqrvmedlgsdyina............................rmiwetnasvivvlGdtddkn.....nfwpekedy
|
|||||||||
subfamily_Cele-PTP-12_pd | Subfamily Cele-PTP-12 | 157-236 | 3.4e-08 | 27.4 | In-house | 33-110 (332) | alignment | ||
Range on Protein: 157-236
Range on HMM: 33-110/332.0
KNKNKNRYANIVAYDHSRVVLERVNGDEdlDYINASFIHGYDGTpRSFIASQGPLPPAFEG-FWRMVWEQNSQSIVMLTNL
.| . || . ..||||| | .| . |. |||.. || ..| .| |. | ||||| |.. |... ..
nnmdmnriphlycfdhsrvelapqdgkd..dfynaswvdgyskk.sayifaqapfndhteyvfwrmvserkpsmilvfgdi
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 158-389 | 6.2e-77 | 253.5 | Pfam-A | 1-235 (235) | alignment | ||
Range on Protein: 158-389
Range on HMM: 1-235/235.0
NKNKNRYANIVAYDHSRVVLERVNGDEDldYINASFIHGYDgTPRSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWP---DKTET
||.|||| .|..||..|| |. .|..| ||||....||. ....|||.||||. .| ||||||......|||||.|. ...||..||| ....|
nkkknRykdilpydktrvklkgsegpsd..YInAnyvkgyk.ekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeeslt
YGGVTVTLH-QSE-VFAGYENCTFILSKEKRS-GSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRALNPRDAGPVIVHCSVGVERTGAYIVIDAMLEQA
|| ..|.| ... ..| .. |.|.|.. .|.|.|.|.| |||.|||. ....| . |||. . . |||.|||| ||.||| ....|..|||.
ygdikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldilleql
KKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLE
.. ..||. ... .||.||.|||. ||| |.. |.||
eaeeevdvlqivkelRkqRpgmvqsleqYiflykaile
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 158-389 | 6.2e-77 | 253.5 | In-house | 1-235 (235) | alignment | ||
Range on Protein: 158-389
Range on HMM: 1-235/235.0
NKNKNRYANIVAYDHSRVVLERVNGDEDldYINASFIHGYDgTPRSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWP---DKTET
||.|||| .|..||..|| |. .|..| ||||....||. ....|||.||||. .| ||||||......|||||.|. ...||..||| ....|
nkkknRykdilpydktrvklkgsegpsd..YInAnyvkgyk.ekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeeslt
YGGVTVTLH-QSE-VFAGYENCTFILSKEKRS-GSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRALNPRDAGPVIVHCSVGVERTGAYIVIDAMLEQA
|| ..|.| ... ..| .. |.|.|.. .|.|.|.|.| |||.|||. ....| . |||. . . |||.|||| ||.||| ....|..|||.
ygdikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldilleql
KKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLE
.. ..||. ... .||.||.|||. ||| |.. |.||
eaeeevdvlqivkelRkqRpgmvqsleqYiflykaile
|
|||||||||
0041856 | (Phosphotyrosine protein) phosphatases II | 158-397 | 5.2e-49 | 161.6 | In-house | 1-177 (182) | alignment | ||
Range on Protein: 158-397
Range on HMM: 1-177/182.0
NKNKNRYANIVAYDHSRvvlervngdeDLDYINASFIHGYDGTPRsFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTnlvglnktkCHKYWPDKTetygg
|..|||| .|. ||||| |||||||... |. . | ||| ||||. .. |.||..|.. ..||.|| .. |||..
nldknrysdilpydhsr..........dldyInanlylgslpatr.fiatqgpllstvadflrmlkelgittivnlt.........eelywpell.....
vtvtlhqsevfagyenctfilskekrsgSRIVRQFHFTVWPDKGVPQyATAVLAFRRKVRAlnprDAGPVIVHCSVGVERTGAYIVIDAMLEQakksrTV
| . |.... ||| ||| .|.| ..|.. . |||.|||| || |||...... |... |
............................erlgiqylylpwpDhgvpd.ldelldfieevle....eggpvlVHCsaGvgRtgtlvaaylmkkl.....gv
DIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTCGNTE
.... . .|..||.||.| .|| |.. |.|| | ...|.
sleeavklvrsrRpgmvitpnqyfflqlallellllkktr
|
|||||||||
subfamily_Cele-PTP-19_pd | Subfamily Cele-PTP-19 | 158-409 | 6.4e-27 | 89.1 | In-house | 50-298 (301) | alignment | ||
Range on Protein: 158-409
Range on HMM: 50-298/301.0
NKNKNRYANIvAYDHSRVVLERVNGDEdlDYINASFIHGYdGTPRSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPDKTET---
.|.|.|| .. . | | |.| | | .| | |. |||.||||. . | || |. . . ||||.. | ...||..| | |..
pkdkhryptv.PckPstavevivdGkr..vPihanwipts.GhphrfiatqgPlkntsedfwamlvqydvekivmlgqkvekleekceeylpvkisekld
YGGVTVTLHQSEVFAGYENCTFILS---KEKRSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRalnpRDAGPVIVHCSVGVERTGAYIVIDAMLEQA
| .......|. . | .. .| | . .. |.|.|||. . . . |. . |..|||| |. |. |.| . . .
igrfkikiknkelilnkkiskrtlevedstgkfatrtvthyqysewtdrgvPkshaelfdlmelvk....ksekPivvhcsaGiGrsvafigteylarev
KKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTCgNTEIQSEKYNQAMQK
. .|... . | .|.|| . |||..| .. . | . ... |.. ..
eadptieltealkhlrehrwngvqtnsqlywmtlGtvyrlik.eygfdmkiyeeqlam
|
|||||||||
subfamily_eak_pd | Subfamily eak | 158-316 | 2.4e-14 | 47.5 | In-house | 52-207 (332) | alignment | ||
Range on Protein: 158-316
Range on HMM: 52-207/332.0
NKNKNrYANIVAYDHSRVVLERVNGDeDLDYINASFIHgYDGTPRSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPDKT---ET
. |.| .|| ||. | | . | ||||| . . | .| . . ||.|| ||.| .||.| . | |. | ||.||||
avnrn.vvkivpydrylvrltssqln.rlGyinaslae.fsevGrkyiltGiasedkvfafwqmvleqkspaivqlledvelkleksdkyfpdktreelk
YGGVTVTLHQSEVFAGYENCTFILSKEKRsgSRIVRQFHFTVWPDKGVPQYAtAVLAFRRKV
.| . |. . . .| ..||| . | ... | . .|.| ||.|. .
fGildverkefvkrniletrllelskGne..thrvlhykvfGwtettlpkye.dflalrkvm
|
|||||||||
subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 159-277 | 1.1e-20 | 68.6 | In-house | 48-178 (350) | alignment | ||
Range on Protein: 159-277
Range on HMM: 48-178/350.0
KNKNRYANIVAYDHSRVVLER--------VNGDEDLDYINASFIHGY----DGTPRS-FIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCH
|||| ||. |.|||| |.. . |||||.... . | .|| |.||| ... |.... . . . |..||..| || ||.
faknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvelnlekcy
KYWPDKteTYGGVTVTLHQ-SEVFAGYENCTFI
.||.. .| ..|| | . | .| ....
rYWqeg..sydditvklaskwenimgindssly
|
|||||||||
subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 159-277 | 2e-12 | 41.1 | In-house | 49-181 (349) | alignment | ||
Range on Protein: 159-277
Range on HMM: 49-181/349.0
KNKNRYANIVAYDHSRVVLERVN--------------GDEDLDYINASFIHGYDGTP-RSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTK
|||| .|. |.||||.|.. . ||||| ... .. . .|| | ||| . . |.... .. . .. |.. |. |
faknrykdilPyehsrvklkkslksskvikastsesdsgklddyinanylkltrisvekkyiatqaPlPstvddfykvillngvklvlsLnddkelslek
CHKYWPDktETYGGVTVTLHQSE-VFAGYENCTFI
|..|| . .| ..|| | | |. . ..
cdiywqe..lsysnitvklqnsslyianvqGnslr
|
|||||||||
0044763 | (Phosphotyrosine protein) phosphatases II | 170-388 | 9.7e-36 | 118.4 | In-house | 2-168 (178) | alignment | ||
Range on Protein: 170-388
Range on HMM: 2-168/178.0
YDHSRVVLERVNGDEDLDYINASFIHGYdgtprSFIASQGPlppafEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPDKTEtyggvtvtlhqsevfa
.|..||.|. . | | ||||||.| .. ...|..| . ......|.. ..||.||. . |.. ||..|||....
ldrtrvllsnleglersdyinaseilpg.....lylgslpp.....addlellkelgithivnlteelelgflkcdpywpeeag................
gyenctfilskekrsgsrivRQFHFTVWPDKGVPQYATAVLAFRRKVRALNPRDAGPVIVHCSVGVERTGAYIVIDAMLEQakksrTVDIRNYLIAIRKH
|.... .|| |||. .|.| . .... ... |||.|||| || |.|. .... |... ... . . .|..
....................iqylhipipDhgvpdllehflefvefieealdekggpvlVHCsaGvgRsgtlvaaylmkkl.....glsleeaielvrer
RPhMVQTKEQYSFIHSAVL
|| .|.. .|. ... |
Rp.ivpnpgqlrqLyefel
|
|||||||||
subfamily_Sponge-PTP-4_pd | Subfamily Sponge-PTP-4 | 172-301 | 6.5e-07 | 23.7 | In-house | 7-125 (130) | alignment | ||
Range on Protein: 172-301
Range on HMM: 7-125/130.0
HSRVVlervngdeDLDYINASFIhGYDGTPRSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLvglnkTKCHKYWPDKT--ETY-GGVTVTLHQSEVF
||. . .||||||. | | . .. .| || . ||.|. |. .|.| . . .|||| | | ..||| . . |
vsrlq........gntyinasfv.Gllgrtaeylltqhpladtsmdfwkmmleryvnvlvvlgsv.....eeedeywpdsePlewyeediivtltdrdef
AGYENCTFILSKEKRSGSRIVRQFHFTVWPDKG
. . ... . . |. . || |
knikasnleiesdlneshqaltmfqisnwpsdg
|
|||||||||
0046846 | (Phosphotyrosine protein) phosphatases II | 180-389 | 9.3e-40 | 131.6 | In-house | 6-171 (176) | alignment | ||
Range on Protein: 180-389
Range on HMM: 6-171/176.0
VNGDEDLDYINASFIHGYDgtprsFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPDKTETYGgvtvtlhqsevfagyenctfils
|.|||||||..| |. .|| ||||| .. |..|..|.. . .|.||..| |.. ||. |||. ..
lgldldldyinanlilgsr.....piatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpeleklgi.......................
kekrsgsrivrQFHFTVWPDKGVPQYaTAVLAFRRKVRALNPRDaGPVIVHCSVGVERTGAYIVIDAMLEqakkSRTVDIRNYLIAIRKHRP-HMVQTKE
|.... ||| |||.. ...| . . .| .. |||.|||| |. |||...... . .. ... . | .|..|| ..||| |
...........qylhlpwpDhgvpdl.elllellefirealkeg.gpvlVHCsaGigRtgtlvaayllel....ekglsveealalvreqRplgavqtpe
QYSFIHSAVLE
|| |.. ..|.
Qyrflyefell
|
|||||||||
0043147 | (Phosphotyrosine protein) phosphatases II | 183-384 | 9.4e-39 | 128.2 | In-house | 2-154 (172) | alignment | ||
Range on Protein: 183-384
Range on HMM: 2-154/172.0
DEDLDYINASFIHGYDGTPRsFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLvglnktkchkywpdktetyggvtvtlhqsevfagyenctfilSKEK
||. ||||||....| ..| ||| ||||. .. ||||..|.. . ||.||.| . .
degsdyinasyldlyyipdr.fiatqgplrntladfwrmlkelgithivnltel..........................................lydp
RSGSRIVRQFHFTVWPDKGVPqYATAVLAFRRKVRA-LNPRDAGPVIVHCSVGVERTGAYIVIDAMLeqakksRTVDIRNYLIAIRKHRPHMVQTKEQYS
.| . |.... ||| ||| . .| | . .. |. .. |||.|||| || |||. .... || . ... . . .|..||..||...||
ellerlgiqylylpwpDhgvp.llellleflefidellalspggpvlVHCsaGvgRtgtlvaaylml......lglsleeavalvrekRpgavqnpsqyr
FIH
|..
fly
|
|||||||||
0051082 | (Phosphotyrosine protein) phosphatases II | 186-388 | 4.4e-32 | 106.1 | In-house | 3-150 (151) | alignment | ||
Range on Protein: 186-388
Range on HMM: 3-150/151.0
LDYINASFIHGYdgtprsFIASQGPLPpafeGFWRMVWEQNSQSIVMLTNLVGLNktKCHKYWPDKTetyggvtvtlhqsevfagyenctfilskekrsg
||||.|.. |. ...|.|||. |.....|.. ..||.|.... . .|..|.|.
sdyinfsyvtgg......lyrsggpla....dflellkelgiktivnlrseeerg..ycpeylpelg.................................
sRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRAlnpRDAGPVIVHCSVGVERTGAYIVIDAMLEQakksrtVDIRNYLIAIRKHRPHMVQTKEQYSFIHS
. |...... ||| |.|.. |||.| ..... . |||.|||| |. |||. .... ||.. |.. | .|..||..||...|. |..
.ievlhipildwpdpglplsfdavleflellld...kkngpvlvHCsaGkgRTGtlvalylmllg......vsleealeeyrlkrpgvvqpnqqflfqlf
AVL
|.|
all
|
|||||||||
0051429 | (Phosphotyrosine protein) phosphatases II | 187-411 | 2.6e-48 | 160.3 | In-house | 5-244 (272) | alignment | ||
Range on Protein: 187-411
Range on HMM: 5-244/272.0
DYINASFIHGYdGT---PRSFIASQGPLPPAFEGFWRMvWEQNSQSIVMLTNLVGLNKTKCHKYWP-------------DKTETYGGVTVTLHQSEVFAG
.||||... || | |. ...|.|||| ..|||. .|.. .||.|.... ... ||..||| . | .|| ..|||.. |..
gyiNardvggy.grvvkpgrlyrsggplpltaadfwrl.kelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseellld
YENCTFILSKE-KRSGSRIVRQFHFTVWPDKGVPQYAtaVLAFRRKVRAlnprdAGPVIVHCSVGVERTGAYIVIDAMLEQAKKSRTVD--------IRN
| ...|... . . .| |...|.| ||| |||| | .|.. . ... |||.|||| |. ||| ..... .|.. .. || ...
yilrellltlllsagearevmhlhytdwpdhgvpqea..llellellld.....ggpvlvHCsaGkdRTGtvvallllllgvsletivddYlltnlylee
YLIAIRKHRPHMVQTKEQYSFIHSAVLEAlTCGNTEIQSEKYNQAMQKLA
.. .|..||..||| ||| |.. |.||. .. .... | ...|.. .
aveelraqrpgavqteeqylflyeallel.lrsllsvraeyllaaldaid
|
|||||||||
0036282 | (Phosphotyrosine protein) phosphatases II | 187-384 | 2.1e-43 | 143.3 | In-house | 3-163 (174) | alignment | ||
Range on Protein: 187-384
Range on HMM: 3-163/174.0
DYINASFIHGYDGTPrSFIASQGPLPpafegFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPDktetyggvtvtlhqsevfagyenctfilskEKRSGS
||||||..... || .||.||||. ||.|..|......|||.... |...||. |||. . . .
dyinaspldlsyitp.rliagqgpla.....fwemlkelgittvvmlleekelglykcinywpe..............................lredle
RIVRQFHFTVWPDKGVPQYATaVLAFRRKVRALNPR-DAGPVIVHCSVGVERTGAYIVIDAMLEQAKkSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIH
| . |.... ||| ||| .. .| | . |. . . |||.|||| || |||. .... || . . ...||. ... ..|..||.|||| .|| |..
rlgiqylylpwpDhgvpdlsi.llefvkfveealsedpggpvlVHCsaGvgRtGtlvaaylmlrgll.eslvdaldlvrelRlqrpgmvqtpsQyrfly
|
|||||||||
0049260 | (Phosphotyrosine protein) phosphatases II | 201-384 | 6.9e-37 | 121.8 | In-house | 8-143 (152) | alignment | ||
Range on Protein: 201-384
Range on HMM: 8-143/152.0
PRSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWpdktetyggvtvtlhqsevfagyenctfilskekrsgsrivrQFHFTVWPDK
|. ||| |||.| .. ||||..|.. . |||||.|. |.| ||..|. |.... |||
pfefiatqgpgpntladfwrmlkelgittivmltellelgklkceqyi..........................................qylhlpwpDh
GVPQYATAVLAFRRKVRALNPRDAGPVIVHCSVGVERTGAYIVIDAMLeqakksRTVDIRNYLIAIRKHRPHMVQTKEQYSFIH
|||. . .| . . .. |. .. |||.|||| || |||...... || . |.. ... .|..||..|....|. |..
gvpdlsqlllflllfieklaldkggpvlVHCsaGvgRtgtlvaaylml......lgvsleeavalvrekRpgavpnpgqlrfly
|
|||||||||
subfamily_Anemone-PTP-3_pd | Subfamily Anemone-PTP-3 | 202-384 | 4.7e-20 | 66.6 | In-house | 5-197 (199) | alignment | ||
Range on Protein: 202-384
Range on HMM: 5-197/199.0
RSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPD---KTETYGGVTVTLHQSEVFAGYENCTFILSKEKR--SGSRIVRQFHFTV
| .||.| || .. ||.|||| | |||. . ... ||| | || ..|| . . . | ...||... .| . .. ||
rryiatqhplretmadfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyqfts
WPDKGVPQYAT---AVLAFRRKVRALNPRDAGPVIVHCSVGVERTGAYIVIDAMLEQAKKSRT--VDIRNYLIAIRKHRPHMVQTKEQYSFIH
| .| |. | |.| | . . ||||||| | || .. .| . ..|.| ||. . .|. | .. . ..| ||.
wkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiisslqhynfiy
|
|||||||||
subfamily_Nvec-PTP-3_pd | Subfamily Nvec-PTP-3 | 202-384 | 5e-20 | 66.5 | In-house | 4-196 (198) | alignment | ||
Range on Protein: 202-384
Range on HMM: 4-196/198.0
RSFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPD---KTETYGGVTVTLHQSEVFAGYENCTFILSKEKR--SGSRIVRQFHFTV
| .||.| || .. ||.|||| | |||. . ... ||| | || ..|| . . . | ...||... .| . .. ||
rryiatqhplretladfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyqfts
WPDKGVPQYAT---AVLAFRRKVRALNPRDAGPVIVHCSVGVERTGAYIVIDAMLEQAKKSRT--VDIRNYLIAIRKHRPHMVQTKEQYSFIH
| .| |. | |.| | . . ||||||| | || .. .| . ..|.| ||. . .|. | .. . ..| ||.
wkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiisslqhynfiy
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 203-267 | 2.1e-07 | 24.6 | In-house | 237-300 (440) | alignment | ||
Range on Protein: 203-267
Range on HMM: 237-300/440.0
SFIASQGPLPPAFEGFWRMVWEQNSQSIVMLTNlvgLNKTKCHKYWPDKTE--TYGGVTVTLHQSEV
.|||.| || . |||.| . . .|.|| . || | ||| .| |.| || . ||
afiatqmpldstvldfwrlvhdyristiimlnq...lndktcsiywpvntrsvtfgpftvghkgsen
|
|||||||||
subfamily_Cele-PTP-9_pd | Subfamily Cele-PTP-9 | 214-391 | 1.4e-17 | 58.7 | In-house | 40-221 (255) | alignment | ||
Range on Protein: 214-391
Range on HMM: 40-221/255.0
AFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWP---DKTETYGGVTVTL--HQSEVFAGYENCTFILSKEKRsgSRIVRQFHFTVWPDKGVPQYATA
. . |.... .... .|||... .. ||..|.| |. . |.|| ..| . | |.. |. . |. .... |..| |. |
tvdkfyqtivqtktevvvmlcdfaeegvekcssyfplekdeklkladvnvtttkssadvvlrtleitstlgekkk..thtvkhysykGWieknaPelare
VLAFRRKVRalnprDAGPVIVHCSVGVERTGAYIVIDAM----LEQAKKSRTVDI--RNYLIAIRKHRPHMVQTKEQYSFIHSAVLEAL
.| . || |. .|.|||| |. |. |..... . . . ... ||.. .. | .|..|. ..| | .| ||. .
ilnilkvvr.....dsksvvvhCstGiGrsaafvlaelvyqkmirsldttetveldylslleelrskrkraihtPlqlafsilmvldlv
|
|||||||||
subfamily_hpo-7_pd | Subfamily hpo-7 | 214-404 | 1.2e-15 | 52.1 | In-house | 46-241 (263) | alignment | ||
Range on Protein: 214-404
Range on HMM: 46-241/263.0
AFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWP---DKTETYGGVTV--TLHQSEVFAGYENCTFILSKeKRSgSRIVRQFHFTVWPDKGVPQYATA
. . |.... .... .|||.. .. || .|.| |. . |.| | ||.| .. . .|.. |. . |... .. |..| |. |
tidkfyqtivqtktevvvmLcDfneegvekcssyfPlekdekqklanvnvcttkvqsdvllktlellstlge.Kkk.thtvkhysykgWiekndpelare
VLAFRRKVRalnprDAGPVIVHCSVGVERTGAYIVIDA----MLEQAKKSRTVDI--RNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTCGNTEIQSE-
.| . .| . ...|||| |. |. |. |.. |. . ... ||.. .. | .|..|. ..| | .| ||. . ... . |
ilnilkvar.....nskslvvhcstGiGrsaafsvaElvyqkmirsldttstveldylsLleelrssrkraihtPmqLafsilmvLdfvlnnfakgelea
KYN
||.
kyq
|
|||||||||
subfamily_Cele-PTP-7_pd | Subfamily Cele-PTP-7 | 214-391 | 5.2e-15 | 49.7 | In-house | 103-288 (302) | alignment | ||
Range on Protein: 214-391
Range on HMM: 103-288/302.0
AFEGFWRMVWEQNSQSIVMLTNLVGLNKTKCHKYWPDKTE---TYGGVTVT---LHQ-SEVFAGYENC-----TFILSKEKRSGSRIVRQFHFTVWPDKG
. | .| .. . | .| |...| .. || .|. || . ..| ||. ... | |. .. . .| |. . | ..|. |||.|
tlekhwalieqynvaivvqlcsfvedeekkcaeyysdkvggelkfgrytvktvsvktdleeftdkksfklytveiknekkkkkvkktvdilafsawpdhG
VPQYATAVLAFRRKVRALNPRdagpVIVHCSVGVERTGAYIVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEAL
|. | . | . . |.||||.|| |||. . | .. .| .. |. . .. .|. | ||...| .. | .|
apkeaytaldilkfcesykkn....vlvhcsaGvGrtGtlvaikyGiqlcskkkvtdllsivlpvrqcryGavqdeqqliylllcvtkgl
|
|||||||||
subfamily_Cele-PTP-12_pd | Subfamily Cele-PTP-12 | 240-394 | 4.2e-08 | 27.0 | In-house | 146-306 (332) | alignment | ||
Range on Protein: 240-394
Range on HMM: 146-306/332.0
NKTKCHKYWPDKTETYGGVTVTLHQSEVFAGYENCTFILSKEKRSGSRIVRQFHFTVWPDK-GVPQYATAVLAFRR--KVRALN--PRDAGPVIVHCSVG
. |.|.||.|. ..... |. .. || |. .. . .|| | | .|.| . | . .|. . ||... |. |
kakicrkfwpekrskkdfpalsiqasddhsethmktfnltvtekkqdhqtvlmhfyewadasklpeymldmrasiklqyirsskktgvcigpimlvcatg
VERTGAYIVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLE-ALTCG
||. . || .. . . . | ... . ||. .| ..| || ... |.| |
vekcaisatidiivsriteehrvgfketmsaikmqrfgcfrtvgpystacemlmkfavttg
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 272-415 | 4e-32 | 106.1 | In-house | 78-218 (440) | alignment | ||
Range on Protein: 272-415
Range on HMM: 78-218/440.0
ENCTFILSKEkrsgSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRALN-PRDAGPVIVHCSVGVERTGAYIVIDAMLEQAKKSRTVDIRNYLIAIRKHR
|...| . | || ..|.|. |||||||..| || . . | . ||..||||.|. ||| |..|..| .||.| .|| ... ..|. |
inasyingie....srtlkqyhyqgwpdkgvpkfagpvlkmiqdvnesqekagngpllvhcsagagrtgviiavdsilreakrsdqidifsfinsmrnnr
PHMVQTKEQYSFIHSAVLEALTCGNTEIQSEKYNQAMQKLASVNG
|.|||| |||.|.| ||||.| ||.| | . . .... |
pqmvqtpeqyafvheavlegllcgdtliledditerveqiqwpnp
|
|||||||||
0048076 | (Phosphotyrosine protein) phosphatases II | 276-388 | 2.2e-23 | 77.9 | In-house | 34-140 (145) | alignment | ||
Range on Protein: 276-388
Range on HMM: 34-140/145.0
FILSKEKRSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRALNPRDaGPVIVHCSVGVERTGAYIVIDAMLEqakksRTVDIRNYLIAIRKHRPHMVQ
. |. |.. .| . |.... ||| |||. . .|.| . .... ... |||.|||| || |||...... ||. . |.. . | .|..||..|.
lnltselellerlgiqylylpwpDhgvpdllellleflefieealkeg.gpvlVHCsaGvgRtgtlvaaylmll.....lgvsleealelvrsqrpgavp
TKEQYSFIHSAVL
. .|. |.. ..|
npgqlrflyefel
|
|||||||||
0048179 | (Phosphotyrosine protein) phosphatases II | 281-385 | 1.3e-22 | 75.5 | In-house | 41-139 (144) | alignment | ||
Range on Protein: 281-385
Range on HMM: 41-139/144.0
EKRSGSRIVRQFHFTVWPDKGVPQYATAVLAFRRKVRALNPRDaGPVIVHCSVGVERTGAYIVIDAMLeqakkSRTVDIRNYLIAIRKHRPHMVQTKEQY
|. . | . |.... ||| |||.... .|.| . .... ... |||.|||| || |||...... |. . ... . | .|..||..|.. .|.
epefleregiqylhlpwpDhgvpdllellleflefieealeeg.gpvlVHCsaGvgRtgtlvaaylmk.....klglsleealalvrsrrpgavpnpgql
SFIHS
|..
rfLle
|
|||||||||
PTPc_DSPc_SM00012 | 289-389 | 1.1e-31 | 104.5 | In-house | 2-105 (105) | alignment | |||
Range on Protein: 289-389
Range on HMM: 2-105/105.0
VRQFHFTVWPDKGVPQYATAVLAFRRKVRALNPRDA--GPVIVHCSVGVERTGAYIVIDAMLEQAKKS-RTVDIRNYLIAIRKHRPHMVQTKEQYSFIHS
|...|.| |||.|||......| . |.|. . . .||.|||| || ||| ....| .|.| .|. ..||| ... ..||.||.||||.|||.|..
vkhyhytgwpdhgvPeesdsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgmvqteeqylflyr
AVLE
|.||
alle
|
|||||||||
subfamily_PTPDC1_pd | Subfamily PTPDC1 | 292-384 | 3.1e-06 | 21.7 | In-house | 85-169 (182) | alignment | ||
Range on Protein: 292-384
Range on HMM: 85-169/182.0
FHFTVWPDKGVPQYATAvLAFRrKVRALNPrDAGPVIVHCSVGVERTGAyiVIDAMLEQAKKsrtVDIRNYLIAIRKHRPHMVQTKEQYSFIH
.. |.| ||. .. | || | . | | ||| | ||| .| ..| ||. .. . . .|..||. .||.|| ...
vynfgwkDygvasleri.Ldiv.kvvafal.qegkvavhChaGlGrtGv..liacylvyakr...ltaekaiklvrskrpksiqtreqvelvk
|
|||||||||
0038934 | (Phosphotyrosine protein) phosphatases II | 293-385 | 5.9e-06 | 21.6 | In-house | 83-171 (194) | alignment | ||
Range on Protein: 293-385
Range on HMM: 83-171/194.0
HFTVWPDKG-VPQYATAVLAFRRKVRALNPRDAGPVIVHCSVGVERTGAYIVIdAMLEqakkSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHS
. .||.| ||.... .. . || | | ||| |. ||| .. .... .. . . . .| ||..... .... ...
lklpfpddgtvPsleillrfldlvdeflnedpggvvaVHCkaGlgRtGtlvaa.YLiy....rlgmsaeeAialfrekRpgaipnqdyleallk
|
|||||||||
subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 314-391 | 1.6e-15 | 51.7 | In-house | 219-295 (297) | alignment | ||
Range on Protein: 314-391
Range on HMM: 219-295/297.0
RKVRALNPRDAgPVIVHCSVGVERTGAYIVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEAL
.|| ||.| ...|||| || |.| . |..|.. .| | |.. | .|. |. .||| ||. ....|||. |
eslraemprna.yllvhcsaGvGrsGvvvlsdvilaklrkkripdvaailsilreqrarlvqtleqfellydavlkkl
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 322-386 | 1.2e-15 | 52.0 | In-house | 245-310 (319) | alignment | ||
Range on Protein: 322-386
Range on HMM: 245-310/319.0
RDAGPVIVHCSVGVERTGAYIVIDAMLEQAKKS-RTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSA
. ||..|||| || ||| | | ... ..| |.||| . . .|. | . |.||||| ||.
esqGPlvvhcsdGvGrtGlviasdiairsleeskrsvdiPqlvssvrrdrasavltkeqyefiykv
|
|||||||||
subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 322-388 | 1.5e-10 | 35.4 | In-house | 260-341 (350) | alignment | ||
Range on Protein: 322-388
Range on HMM: 260-341/350.0
RDAGPVIVHCSVGVERTGAYIVIDAMLE-------QAKKSRTVDIRNY--------LIAIRKHRPHMVQTKEQYSFIHSAVL
. |..|||| || ||| .. .| .|. |.|| .| . . .|| | |||...|. ||. |.|
arsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaaktrDlisiivnelrkqrismvqnldqfifiYeall
|
|||||||||
subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 322-389 | 1.6e-06 | 21.7 | In-house | 263-342 (349) | alignment | ||
Range on Protein: 322-389
Range on HMM: 263-342/349.0
RDAGPVIVHCSVGVERTGAYIVIDAMLE----QAKKSRTVDIRN-------YLI-AIRKHRPHMVQTKEQYSFIHSAVLE
. ...|||| | ||| .. .| .|. ..| ..... . . .|| | ||| |. .|. |.|.
dqlstllvhcsaGcGrtGvlvtldlllsileplqnesnkiklqallkDlisiivnelrkqrismvqnlaqfiaiyealLk
|
|||||||||
subfamily_eak_pd | Subfamily eak | 324-402 | 6.6e-11 | 36.2 | In-house | 237-317 (332) | alignment | ||
Range on Protein: 324-402
Range on HMM: 237-317/332.0
AGPvIVHCSVGVERTGAYIVIDAMLE--QAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTCGNTEIQS-EK
| |. .. | |.|...||| ... ..|| . . .... ....| | | .. |.|||. .||. | | ... .|
fap.iiqsarGsaraGvfvvidllirlidnkkknlysvedlilkvkskrihsvlvalqhsfiyeivldyllrrnnrlrdlkk
|
|||||||||
subfamily_Sponge-PTP-7_pd | Subfamily Sponge-PTP-7 | 328-394 | 2e-15 | 50.9 | In-house | 2-68 (69) | alignment | ||
Range on Protein: 328-394
Range on HMM: 2-68/69.0
IVHCSVGVERTGAYIVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTCG
.|||| | |||..| | . . | . ||| | . .|| || || . .| ||| |. ||| |
vvhcssgtgrtgtfiaimvemarikseklvdifnnvqymrkcrpmmvmneieyifihdalvealklG
|
|||||||||
subfamily_Sponge-PTP7_pd | Subfamily Sponge-PTP7 | 328-394 | 3.9e-15 | 50.0 | In-house | 1-67 (69) | alignment | ||
Range on Protein: 328-394
Range on HMM: 1-67/69.0
IVHCSVGVERTGAYIVIDAMLEQAKKSRTVDIRNYLIAIRKHRPHMVQTKEQYSFIHSAVLEALTCG
.|||| | |||..| | . . | . ||| | . .|| || || ...| ||| |. ||| |
vvhcssGtGrtGtfiaimvemarikseklvdifnnvqymrkcrpmmvmneneymfihdalvealklG
|
|||||||||
0050432 | (Phosphotyrosine protein) phosphatases II | 391-623 | 2.7e-53 | 176.7 | In-house | 12-240 (308) | alignment | ||
Range on Protein: 391-623
Range on HMM: 12-240/308.0
LTCGNTEIQSEKYNQAMQKLAS-VNGKFPMTGYALEFQRLNSVTSreipVEEKSVGEKPQNLHKNRFSDIIALNSCRVMLhkehaDEESDYINAVFLHAH
|....|.|. ..... ...|. ..... .... ||..|.||. ..| ||...|.| .|||..||... ..|| | ||.|||||| . . .
llfrdtsilvsslklsvldllkllekaldlglleeefeellsvkp....lleysvallpenkdkNrykdilpydhsRVkl.....degsdYInAsyvdgy
--RGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEYWPDH---GATKYGHIGISVLSKQKKGDVICVKPKVTR--KKKTHEVRHL
. ...|||||.|| .||||||||| .... .||||..|.. . .|||. | ..||.. . .|| ....|... . ..| ......|.|.
ssklprkfIatqgPlpntvedFwrmvweqnvrvIvmLtklvengrekcaqYwplelgggsleygkftvtllseevlddytvrtleltnlgdgesrtvthf
HHVSWTDKCIPKVSRSVLDLLDEVQTSQqqcGNVPVLVQCR
|. .| | ..| ...||.|..|..|. .. |..| |.
hytnWpdhgvPpspeilldflelvrksl...pggpivVHCs
|
|||||||||
subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 394-622 | 1e-102 | 338.4 | In-house | 1-230 (298) | alignment | ||
Range on Protein: 394-622
Range on HMM: 1-230/298.0
GNTEIQSEKYNQAMQKLASVNGKFPMTGYALEFQRLNSVTSrEIPVEEKSVGEKPQNLHKNRFSDIIALNSCRVMLHKEHADEESDYINAVFLHAHRGRN
|||||..|....|.||||.|. |. .|||||||||||||.| ||. |||.|..||.| .|||..|||||.|.||.|.||.||||||||||.||||..|||
gnteieaedlkaalqklaavkkkkkltgyalefqrlnsvss.eieeeekevarkpenkkkNRyadiialdssRvvLekedadeesdYiNAsflhaykgrn
AFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEYWPDHGATKYGHIGISVLSKQKKGDVICVKPKVTRKK--KTHEVRHLHHVSWTDKC
||||||.|| |||||||||||..||||||||.||... . ..||||.|...||.| .|.|||....|.|..| ||..|| |..|||.||..||.||.
afiatqaPltetvedFWrmvteedigtiVmltnleeldktkyhkywPdegketygeitvsllskeefadlivrklkvskkkeekerevrqlhftsWpdkg
IPKVSRSVLDLLDEVQTSQQQCGNVPVLVQC
.|....||||||..|..||||.||.||.|||
vpenatsvldllrkvrasqqqagnkpvivqC
|
|||||||||
0051299 | (Phosphotyrosine protein) phosphatases II | 394-623 | 4.2e-54 | 179.3 | In-house | 1-227 (288) | alignment | ||
Range on Protein: 394-623
Range on HMM: 1-227/288.0
GNTEIQSEKYNQAMQKLAsvngKFPMTGYALEFQRLNSVTSReipvEEKSVGEKPQNLHKNRFSDIIALNSCRVMLHKEHADEESDYINAVFLHAHRGRN
|.|||. |.. ....|| . .||.. ||..| |.. . |.. .|.||.|||.|||......|| |. .. .|.|||||| ... .. .
gdteisveellklvlkll....angltglleefeellsllpd....ltlsaallpenleknRysdilpydhsRVkLsvldgvegsdYinAsyidgynlkr
AFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEYWPDHGATKYGHIGISVLSKQKKGDVICVKPKVT------RKKKTHEVRHLHHVSW
.|||||.|| .||||||||| .... .||||..|.. . |||..| ..||.| . || ....|... . .|| ......|.|.|. .|
kfIatqgPlpntvedFWrmvweqnvrvIvmltklvelgrekcaqYwplggsltygditvtllseevlddytvrtlevtnldlldgdgesrtvthfhytnw
TDKCIPKVSRSVLDLLDEVQTSQQqCGNVPVLVQCR
| ..| ...||.| .|..... |. ||.| |.
pdhgvpdspellldflrlvrkala.sgggpvvVHCs
|
|||||||||
subfamily_PTPN6_pd | Subfamily PTPN6 | 396-622 | 6.4e-38 | 125.5 | In-house | 2-234 (306) | alignment | ||
Range on Protein: 396-622
Range on HMM: 2-234/306.0
TEIQSEKYNQAMQKLASVNGKFPMTGYALEFQRLNSVTSREipVEEKSVGEKPQNLHKNRFSDIIALNSCRVMLHkEHADEESDYINAVFLH--AHRGRN
|.. ... .| ...| . .. .|. ||..|. ... . ... |.||.| .|||. |. . ||.|. |. .|||||| ... .. ..
tsllakeieqrvselekeeeslekagfeeefeelqqeeakk..llsrkegakpenkeknryknilPfDhtrvilk.epsvpgsdyinanyikkevkgsdk
AFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEYWPDHGAT-KYGHIGISVLSKQKKGDVICVKPKVT---RKKKTHEVRHLHHVSWTD
..|||| | .||.|||||| . . |||. . .. . ||||. .. .||.| .. .|.... | | . .|. .||...||...|. || |
syiatqgclettvsdFWrmvwqensrvivmttkevErgkekCarYWPdeeekeeyGkisvtnvseksladYilRelsvskkkkkkeerevfqyhfksWPd
KCIPKVSRSVLDLLDEVQTSQQQCG---NVPVLVQC
. .|| |||.|..|.. |... . |..| |
hgvpkdpgavLdfledvnrkqeeleeaeagpivvhC
|
|||||||||
subfamily_PTPRB_pd | Subfamily PTPRB | 397-622 | 8.5e-45 | 148.0 | In-house | 6-225 (293) | alignment | ||
Range on Protein: 397-622
Range on HMM: 6-225/293.0
EIQSEKYNQAMQKLASVNGkfpmTGYALEFQRLNSVTSREipveEKSVGEKPQNLHKNRFSDIIALNSCRVMLHKEHADEESDYINAVFLHAHRGRNAFI
.|. ||... ..|... . .... |...|..| . . .... |...| |||...|.. . || |.. . ...|||||| ... .. .. ||
piklekfeehvkkmkadsd....lrfseeyeelkavgkdq....avkaaelavnraknrytnilpydhsrvkLaalkdesgsDYinanyipgynsprefi
ATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEYWPDH-GATKYGHIGISVLSKQKKGDVICVKPKVTRKKKTHEVRHLHHVSWTDKCIPKV
||| || |||.|||||| . .|||| .| .. ||||.. .. ||.| ......... | .. . |....|....||..|..||.| .|.
atqGPlpetvddfWrmvwekkssiivmltqlvekgkvkCeeYWPadeepvlyGdikvtlvaeeeledwvirelkiekekeerkvrqyhftsWpdhgvPek
SRSVLDLLDEVQTSQ-QQCGNVPVLVQC
....||.. .|.... ... . |..| |
tktlldfvrtvreaiektaskrPivvhC
|
|||||||||
subfamily_Cele-PTP-14_pd | Subfamily Cele-PTP-14 | 401-565 | 5.3e-22 | 72.8 | In-house | 8-167 (310) | alignment | ||
Range on Protein: 401-565
Range on HMM: 8-167/310.0
EKYNQAMQKLASVNGKFPMTGYALEFQRLNSVTSREIPVEEksvgeKPQNLHKNRFSDIIALNSCRVMLHKEHADeESDYINAVFLHAHRGRNAFIATQH
|| .|.... |. . | . ....|.. . | ...||||.||.. |...|| |. ... ||| | .... |..|| .|
lkylkalenfiiateklgieglvkqyrkldakqdssltyea.....ykkymhknrysdvvcldtsrvklkidksr.yedyihanyvktnylrstficsqg
PLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEYWPDHGATK-YGHIGISVLSKQKKGDVIC
|| |. |||||. . .|..| . .. | . ||| | |. || | .. ||. . ||
plqhtiidfwrmifqeraesilllckvgeegrpkcvgywpslgvtetygcirvtnlsesseefeic
|
|||||||||
subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 405-622 | 2.3e-26 | 87.1 | In-house | 12-223 (290) | alignment | ||
Range on Protein: 405-622
Range on HMM: 12-223/290.0
QAMQKLASVNGKFPMTGYALEFqrLNSVTSR-EIPVEEKSVGEKPQNLHKNRFSDIIALNSCRVMLHKehaDEESDYINAVFLHAHrgRNAFIATQHPLL
.|..|.|| | . ..| |. |. . |... .| ...|||. |.. . ||.|. . ||. | ... . || || .|
eafekfasdvvkknvdelakey..leklkpylpvqylerkifdkntefkknrykdvvcndktrvilkd...GydGdyvhanyvkGl..kamfiltqGalk
ETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEYWPDHG--ATKYGHIGISVLSKQKKGDVICVKPK-VTRK--KKTHEVRHLHHVSWTDKCIPKVSRS
.|| |.|||| . .. .|||| .| .. . ..|.|.. . .|.| . ...| . | | | | | | ..||. .|| ||.... . .
dtvidiwrmvlqekvaaivmlceliedGkakceqyypekeGevltfGeitvlcseeddkdaniikktlsvrdkdsGkehklkhlkikswpdksvalstla
VLDLLDEVQTSqqqCGnvPVLVQC
.| .| ... | || | |
llrtlrilrka...sG..pvvvhc
|
|||||||||
0039614 | (Phosphotyrosine protein) phosphatases II | 412-623 | 1.4e-46 | 154.7 | In-house | 24-230 (297) | alignment | ||
Range on Protein: 412-623
Range on HMM: 24-230/297.0
SVNGKFPMTGYALEFQRLNSVTSreipvEeKSVGEKPQNLHKNRFSDIIALNSCRVMLHKEHA-DEESDYINAVFLHAHRG-RNAFIATQHPLLETVEDF
.. .. .|.. |||..| |.. . .|....|.| .|||..||......|| |. | |..|||||| .. .. ..|||||.|| ||||||
llekansktllllefeellslkp.....d.ysiallpenkdknrykdilpydhsrvklkpedgvdldsdYinAsyvdgydlltrkfIatqgPlpetvedF
WRMVTDYDIGTIVMLNNLHDQVApESSEYWPDHGAtKYGHIGISVLSKQKKGDVICVKPKVTRKKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTS
|||| .... .||||..| . .|||. | .||.. . .|. ....... . .||.......|.|.....| | ..| ....|..|..|..
wrmvweqgvtvivmLtklvelgr.kcaqywpeegg.tygdftvtllkvehldgytvrtlevtnngesrtvthfqytgwpdhgvppslellleflelvrea
QQQC-GNVPVLVQCR
.... .. |||| |
laelpkggpvlVHCs
|
|||||||||
0047943 | (Phosphotyrosine protein) phosphatases II | 413-623 | 1.4e-48 | 161.1 | In-house | 5-213 (273) | alignment | ||
Range on Protein: 413-623
Range on HMM: 5-213/273.0
VNGKFPMTGYALEFQRLNSVTSreipVEEKSVGEKPQNLHKNRFSDIIALNSCRVMLhkehADEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRM
..... .|....||..| |.. . ..||...|.|..|||..||......|| | |..|||||| .. .. ..|||||.|| .||||||||
lekllgltllleefelllslkp....lltysvallpenkdknrykdilpydhsrvkl....gdggsdyinAsyvdgynlkrkfiatqgPlpntvedfwrm
VTDYDIGTIVMLNNLHDQVAPESSEYWPDHG---ATKYGHIGISVLSKQKKGDVICVKPKVTR--KKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQ
| .... .||||..|.. . |||. | ..||.. . .|| ..|.|.. . ..|. .....|.|.|. .| | ..| |.|.....|.
vweqnvrviVmLtelvelgrekcaqYwpleggelsltygkftvtllseetkddytvrtleltnlgtgesrtvthfhytgwpdhgvppslesllefielvr
TSQQQC-GNVPVLVQCR
. .... .| ||.| |.
kalealpsngpvvVHCs
|
|||||||||
0036941 | (Phosphotyrosine protein) phosphatases II | 413-623 | 1.1e-47 | 158.2 | In-house | 6-215 (297) | alignment | ||
Range on Protein: 413-623
Range on HMM: 6-215/297.0
VNGKFPMTGYALEFQRLnsvtSREIPVEEKSVGEKPQNLHKNRFSDIIALNSCRVMLhkehADEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRM
..... .... ||..| . .. ..||...|.||.|||..||......|| | ||.|||||| .. .. ..|||||.|| .||||||||
lekllflalllkefeel....lpllllgslsvallpenleknRykdilpydhtRVkl....ddegsdYinAsyvdgydlkrkfIatqgPlpntvedFWrm
VTDYDIGTIVMLNNLHDQVAPESSEYWPDH--GATKYGHIGISVLSKQK--KGDVICVKPKVTR--KKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEV
| .... .||||..| . . .|||. . .||.. . .|| .. ..|.. . .|| ......|.|.|. .| | ..| .|.||....|
vweqnvtvIvmltelvelgrekcaqywpleegesltygdftvtllsvevvllddytlrtlevtdtgngesrtvthfhytgwpdhgvpespaslldfielv
QTSQQQC-GNVPVLVQCR
.. ... .. |||| |.
rkvlkllpsggpvlVHCs
|
|||||||||
0043336 | (Phosphotyrosine protein) phosphatases II | 414-623 | 1.1e-44 | 148.4 | In-house | 14-218 (278) | alignment | ||
Range on Protein: 414-623
Range on HMM: 14-218/278.0
NGKFPMTGYALEFQRLNSVTSreipvEEKSVGEKPQNLHKNRFSDIIALNSCRVMLHKEHADEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMV
.. |.. |||..|.|.. ...|....|.| .|||..||......|| |. . |. |||||| .. .. ..|||||.|| ||||||||||
lllnlktllllefeellsfkl.....dtysiallpenkdknrykdilpydhsrvklsllggdldsdYinAsyvdgynvprkfiatqgPlpetvedFwrmv
TDYDIGTIVMLNNLHDQVAPESSEYWPdHGATKYGHIGISVLSKQKKGDVICVKPKVT--RKKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQ
.... |||||..| . . . .||| | ..||.. . .|. ....|.. . .|| .......|.|.|...| | ..| ..||.| .|.. ..
welgvttivmLtelvelgrvkcaqYwp.ggsltygdftvtllkeehlddytvrtlevtnlgdgesrtvthyhylgwpdhgvpeslsllldflkavreale
qCGNVPVLVQCR
| |||| |.
.dsngpvlVHCs
|
|||||||||
subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 418-622 | 1.2e-41 | 137.6 | In-house | 13-215 (281) | alignment | ||
Range on Protein: 418-622
Range on HMM: 13-215/281.0
PMTGYALEFQRLNSVTSREIPVeeksVGEKPQNLHKNRFSDIIALNSCRVMLHKEHADEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYD
.|.. |.. |... .. . ....| .|||.|.|.| . || ..........||||| |. . .| ...|||| |. .....||.|| ...
dnaGfieeyeklaaigvdntat....askadenvlknrYsnivaYDatrvkvtpneenkntDYinanfvpgykgekeyiatqgPvPaslvafWqmvweqk
IGTIVMLNNLHDQVAPESSEYWPDHG-ATKYGHIGISVLSKQKKGDVICVKPKV-TRKKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQQCGN
. .|||. . .. ||||. ..|||.. .. .....| |. | |. ... .| ||..|....| |. .|. .. .|. .||. ... .
vsaivmvtreieagklkChrYWPddnselkygdvtvkstaeeekatyierkfkleresgetreveqlaytaWPdhGvPattkellefrkevlkltekktk
VPVLVQC
.|... |
aplvihC
|
|||||||||
0045450 | (Phosphotyrosine protein) phosphatases II | 419-623 | 3.8e-46 | 153.6 | In-house | 26-242 (307) | alignment | ||
Range on Protein: 419-623
Range on HMM: 26-242/307.0
MTGYALEFQRLNSVTSREipVEEKSVGEKPQNLHKNRFSDIIALNSCRVMLHKEHAD-EESDYINAVFL--------HAHRGRNAFIATQHPLLETVEDF
.||.. ||..|.||| . . | |....|.| .|||..||......|| |. .. . |.|||||| . . .. ..|||||.|| ||||||
ltgllkefekllsvtvfl..lgeysiallpenkdknrykdilpydhtRVklssldgsledsdYiNAsyvrvpllllldgydlkrkfIatqgPlpetvedF
WRMVTDYDIGTIVMLNNLHDQVAPESSEYWPDHGAT-KYGHIGISVLSKQKKGDVICVKPKVT---RKKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDE
|||. ......||||..| . . .|||| | . ||.. . .||......... . .|| ......|.|.|. .| | ..|. ..||...|
wrmlweqgvtvivmltelvelgrekcaqywPdegeeltygnftvtllseehldgytvrtlevtdldgtgesrtvthfhytgwpdhgvppsfeelldfiee
VQTSQQQC-GNVPVLVQCR
|.. .... .. |||| |.
vrkaleelpkggpvlVHCs
|
|||||||||
subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 419-622 | 2.2e-36 | 120.3 | In-house | 19-218 (287) | alignment | ||
Range on Protein: 419-622
Range on HMM: 19-218/287.0
MTGYALEFQRLNSVTSREipvEEKSVGEKPQNLHKNRFSDIIALNSCRVMLHkehaDEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDI
.|. |. |..|| || .| .. .|| .|||...|. . ||.|. .|. |||||||. ... ..|||... |. .|. .||... | .
negfknqftvleqvtqre...devthniasqnkdknRltqilvpdnyrvllk....gehpdyinavfidgykekkafiiaesPmfntarnfWkliddrnv
GTIVMLNNLHDQVAPESSEYWPDHGATKYGHIGISVLSKQKKGDVICVKPKVTRKKK---THEVRHLHHVSWTDKC-IPKVSrSVLDLLDEVQTSQQQCG
.|||| ..... .|||.. .. .|. |..|..... ..| | .|..|.| ...|. . .| .. ... ..| ...| .|.. |
taivmlcqekendeevcyqyWpeeksvvlGeyniellneevnagyierklevknknkagdkqqvkqyqitnWdstgkvtepq.tillvieemyktqrkrg
NVPVLVQC
| ...| |
ntsivvhC
|
|||||||||
subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 419-622 | 7.3e-35 | 115.2 | In-house | 19-223 (290) | alignment | ||
Range on Protein: 419-622
Range on HMM: 19-223/290.0
MTGYALEFQRLNSvTSREIPVeekSVGEKPQNLHKNRFSDIIALNSCRVMLH--KEHADEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDY
..|. .|..|.| ...| | || ..| ..|||..|. . |..|. .| | . .||||.... .. ....|||| |. .|. |||... .
negfrnqfkmlds.gesehtv...tvgltssnkllnRfanivvyddnritLrpisghkDCtneyinAcyikgykekkqyiatqgpvsntlvdFWkliwqe
DIGTIVMLNNLHDQVAPESSEYWPDHGATKYGHIGISVLSKQKKGDVICVKPKVTRKKK---THEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQQC
.. |||| | .. . ||||.....||.. | .|. .. . | | .|. |.. ...| ... .| .. . ..| .. |.. | .
kvtiivmltniieegkvkCqqYWpdsdtkaygefsikllneetlneyierklevknknsagakqsvtqyqitnwdstgkvtnpqtillvieemyktqrkr
GNVPVLVQC
|| ...| |
gntsivvHC
|
|||||||||
0040438 | (Phosphotyrosine protein) phosphatases II | 420-623 | 2.4e-48 | 160.4 | In-house | 18-217 (317) | alignment | ||
Range on Protein: 420-623
Range on HMM: 18-217/317.0
TGYALEFQRLNSVtsreiPVEEKSVGEKPQNLHKNRFSDIIALNSCRVMLHKEHADEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIG
|. ||..| |. .... ||.|.|.| .|||..||. . ..|| |. . |..|||||| . . .. ...|||||.|| .||||||||| .....
talleefedllsl.....kldtysvaelpenkdknrypdilpydhsRVkLsplggdldsdYInAsyvdgpnlkrkfIatqgPlpntvedFwrmvweqgvt
TIVMLNNLHDQVAPESSEYWPDHGATKYGHIGISVLSKQKKGDVICVKPKVT--RKKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQqCGNVP
.||||..| . . . .|||. . ..||.. . .|| ....... . .|. .......|.|.|. .|.| ..|. ...||.|..|..... .. |
vivmLteleelgrekcaqYwplgetltygdftvtllseeelagitlrtlevedlgdsesrtvthfhytgWpdhgvppspdllldfleavreale.dpggp
VLVQCR
||| |
vlVHCs
|
|||||||||
subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 420-622 | 1e-47 | 157.6 | In-house | 21-219 (288) | alignment | ||
Range on Protein: 420-622
Range on HMM: 21-219/288.0
TGYALEFQRLNSVTSReipvEEKSVGEKPQNLHKNRFSDIIALNSCRVMLHKEHADEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIG
||. |.. | .. . .....|....| .|||. .|.... || |.| . ...||||| ... .......|||| || .||.|||..| ....
tgfseeynsLaalekt....ksvtagrlavnakknRyrnilpyDekrvklkkleeeagaDYinasyidgekkkkkyiatqgPladtvndfWelvyenkts
TIVMLNNLHDQVAPESSEYWPDHGA-TKYGHIGISVLSKQKKGDVICVKPKVTRKKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQQCgNVPV
|||||..| .. . ||||| . ..||.. . ........|.. | . .||. |. .... .|.|. .|. .. .|.||. |....|. |.
tivmltelveggktkCeeYWPdadkpknyGsvtvtlveskeledfvlrklllekkkteleitqyqylaWpdhgvPeskapllellrqvkvanqad.tgpi
LVQC
.|.|
ivhC
|
|||||||||
subfamily_PTPRG_pd | Subfamily PTPRG | 420-624 | 9.4e-40 | 131.3 | In-house | 19-229 (563) | alignment | ||
Range on Protein: 420-624
Range on HMM: 19-229/563.0
TGYALEFQRL-NSVTSREIPVEEksvGEKPQNLHKNRFSDIIALNSCRVMLHKEHADEES-DYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYD
.|.. ||. | . ..|.....| .||.| .||| ..|.| .. || |.. ... ||||| ... .. .||||||.|| .|..|||||. .
igfseefealqsetiskdldaeh...sqkpenkrKnRylnivaydrsRvklsplpgkkkklDYinAnyidGyqkskafiatqgplkdtfddFWrmiWeqn
IGTIVMLNNLHDQVAPESSEYWPDHGATKYGHIGISVLSKQKKG----DVICVKP-KVTRKKK---THEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTS
.|||. || .. . . ||| .. .||.. . ..... . .| |. .||. ..||. | .| |.. |. | || ...
vaiivmitnlvergrrkcdvYWPkdesetygalqvtlieeevlalytvrtlviknlklkkkkqcdteklvrqyhytkWPdhgvPehslpvLifvkkssaa
QQQ-CGnvPVLVQCRY
... | |..| |..
nkaeaG..PivvHcsa
|
|||||||||
subfamily_PTPN23_pd | Subfamily PTPN23 | 420-622 | 1.9e-34 | 113.8 | In-house | 15-219 (288) | alignment | ||
Range on Protein: 420-622
Range on HMM: 15-219/288.0
TGYALEFQRLNSVTSREipVEEKSVGEKPQNLHKNRFSDIIALNSCRVMLHkehaDEESDYINAVFLHAH-RGRNAFIATQHPLLETVEDFWRMVTDYDI
|. .|. |.. .| ...|. . .|||. ||. .. ||.|. ... ||||| |.. | ||||| || .|. |||.|| .
taldkkfkeleqkqdke..arkrsiaiaklyseknrsrdilPyDhnRvklr....gskDDYinAsfvkdlspgcPdfiatqaPlqstlnDFWlmvyeqks
GTIVMLNNLHDQVAPESSEYWPDH--GATKYGHIGISVLSKQKKGDVICVKPKVT--RKKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQT---SQQ
.|||| . ... |. ..||| . ..|.|.. ... |... . .. . |.. .......|.||. ||.. .|. ..|..||||.. ..|
sviVmllskeelgkpkvdrYwPedkgetvkfgdlsvtlksvretethvervlkletldadavksvshlqltsWpelGvPasPetllqfldevesayeavq
QCGNVPVLVQC
. ..|..|.|
rksktPlvvhC
|
|||||||||
subfamily_CG7180_pd | Subfamily CG7180 | 420-623 | 4e-29 | 96.2 | In-house | 13-231 (296) | alignment | ||
Range on Protein: 420-623
Range on HMM: 13-231/296.0
TGYALEFQRLNSVTSReIPVEEKSVGEKPQNLHKNRFSDIIALNSCRVMLHKEHADEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIG
. .|.. . .|.| . .. | . .|. ||| ... . ||.|.| . .|.|||||||. .. ...| |. | |||..|||.| | .|
rkfrveyklelkltpr.leigdCagglrkenreknrdvkvvPyDynRvvLekldGeeksdYinavyvdsflkkkeyivteapkketvdefWrlvydeeis
TIVMLNNLHDQVApESSEYWPDHGATKYGHIGISVLSKQKKGDVICVKPKVTRK------------KKTHEVRHLHHVSWTD-KCIPKVSRSVLDLLDEV
..|.| . |. .||| .. ..||.| . ...... .. . |.|.| .| |.... | . .| .. ....|. |
avvvLtktfdfak.mypsywpnkskeqygeifveiveekqyanlkirtfkltkkivalteqekqvkaetRivklfqlteWeledkvPlstnalielrrrv
QTSQQQC----GNVPVLVQCR
.. ... . ||.| .
rlwrekvdedpeegPvvvvss
|
|||||||||
subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 421-622 | 5.3e-47 | 155.4 | In-house | 24-223 (319) | alignment | ||
Range on Protein: 421-622
Range on HMM: 24-223/319.0
GYALEFQRLNSVTSReipveEKSVGEKPQNLHKNRFSDIIALNSCRVMLHKEHADEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGT
. . ||. |. .. . . .|..| .|||...|.| . .||.| . . |.|||||| |. ... |..||||| || .|.||||||| .... .
llekefkllkeavnd.....tfdsaskeenkkknryqnilaydrtrvvlseldgvegsdyinasfidgyqerekfiatqaPlentiedfWrmvWeeessi
IVMLNNLHDQVAPESSEYWPDHGATKYGHIGISVLSKQKKGDVICVKPKVTRKKKT---HEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQQCGNVP
.|||..| ... . ..|||.. ..||.. . ....... |.| | |. .|. || | .. .|.|. .|. ..|.|||| ... |... . |
vvmltklveklkvklkkywpeenfeeyGrlivtleeeeeledyiirklklnkkssevetRevkhfqyteWpdhdvPekatslldllkrirksrektqsgP
VLVQC
. | |
ivvhC
|
|||||||||
subfamily_Ptp69D_pd | Subfamily Ptp69D | 421-624 | 4.7e-45 | 149.0 | In-house | 23-228 (307) | alignment | ||
Range on Protein: 421-624
Range on HMM: 23-228/307.0
GYALEFQRLNSVtsrEIPvEEKSVGEKPQNLHKNRFSDIIALNSCRVMLHKEHADEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGT
|.| |...|.. ||. . .|.|| |. |||. ||.| .. ||.|.| .|.|||||| |..... .. ||| | |. .|..|||||... .. .
glakeyekLear...eid.kstkvsekkenalknRyedikafDktRvkLkkingkedsdYinasfikgykekkkfiaaqdPveatigDfWRmiaeqevtl
IVMLNNLHDQVAPESSEYWPDHGATKYGHIGISVLSKQKKGDVICVKPKVTRKK-------KTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQQC
|||| || .. . . |||. ..||.| . . |..|..| | . .|..|| ....| |. .| | .|.|.|..|.|...|. ...
ivmlsnlteknrkkcakYWpiedevqygdilvklvseekhsdyiiReldvskkkeesgevedsrkvvqyhytgWkDskvPevargllklieqvrelykln
gNVPVLVQCRY
. |..| |.
.rsPivvhCsa
|
|||||||||
subfamily_PTPN12_pd | Subfamily PTPN12 | 421-622 | 5.3e-44 | 145.2 | In-house | 9-214 (290) | alignment | ||
Range on Protein: 421-622
Range on HMM: 9-214/290.0
GYALEFQRLNSVTSREI--PVEEKSVGEKPQNLHKNRFSDIIALNSCRVMLHKEHADEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDI
.| |||.| ..... | ....|||..| .|||. ||. . ||.|.|.. .|.|||||| |.. |. ..||.| || .|..|||||. ....
efakefqklkklsekykaekvysteagekeenvkknrykDilPydksrvelskieeeegsdYinanfikgvegkleyiaaqgPLpktlddfWrmiweknv
GTIVMLNNLHDQVAPESSEYWPDHGAT--KYGHIGISVLSKQKKG-DVICVKPKVTRKKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQqCGN
.||. .. . |||..| . ..|.. ... .... | . ||...|....|. .|. .| |. .|. |.|.|...|.. |. .
eivvmaCrevelgkkkCerYWpeegeeelefgefevtleeekavdddflirtLkveaqkesrkvyqfhYtaWPDhgvPssaksllelielvrelqe.sed
VPVLVQC
.|..| |
aPlvvhC
|
|||||||||
subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 421-622 | 5.5e-37 | 122.6 | In-house | 24-228 (325) | alignment | ||
Range on Protein: 421-622
Range on HMM: 24-228/325.0
GYALEFQRLNSVTSReipveEKSVGEKPQNLHKNRFSDIIALNSCRVMLHKEHADEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGT
|.| ||. | |. . | | ||.| |||| ...||. ||.| . | .|||||| .|. ..... |.|.| || .|..|.||.| |.
gfahefgllpsddgi.....akkvamkpenkaknrfknvvaldksrvvletkkddpssdyinasylrddkkkdvflaaqaPltatindlWrlvldWrcsv
IVMLNNLHDQvAPESSEYWPDH--GATKYGHIGISVLSKQKKGDVICVKPKVTRKKK--THEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQQ----
.|.|| | . . . |||.. . ..| . ... . .. | . . .| . || | |. ... || | .| ... .|. |.. ...
vvvlneldlg.kdrcavywpkemgksktfGglevklrtieeisdyvhrvldvkqvkkGetrsvkqfqlqswddmGvqkrpatlisilqlvkavservtan
-CGNVPVLVQC
. |.|| |
tkastpilvhc
|
|||||||||
subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 423-622 | 4.3e-49 | 162.3 | In-house | 23-220 (318) | alignment | ||
Range on Protein: 423-622
Range on HMM: 23-220/318.0
ALEFQRLNSVtsREIPVEEKSvgEKPQNLHKNRFSDIIALNSCRVMLHKEHADEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIV
|..||. . .| . . || .| | .|||. .|.| ...|| |.. . .|.|||||| .. .| ..|.||.| || ||.||||||| . . .||
seeyerlsrs..eetvtslks..lepvnkaknryanilaydhtrvkLqmlegeegsDyinanyidGyrrkkayiaaqaPlpetieDfWrmvWeqnsaviv
MLNNLHDQVAPESSEYWPDHGATKYGHIGISVLSKQKKGDVICVKPKVTRKKK--THEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQQCGNVPVLV
|| ..... |||..|...||.. . . .. . .| . . ||||... . .|| |. ||.|. .|. . |.|||. .|.. ||..|. |..|
mltqeeergkakvhryWPskgsrsygklvvelkeevelsdyvlrefkvtrteeeesrqvrqyhytsWpdegvpesgaslldlvrqvskaqqksgagpivv
QC
|
hC
|
|||||||||
subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 423-622 | 1.5e-33 | 111.5 | In-house | 37-231 (319) | alignment | ||
Range on Protein: 423-622
Range on HMM: 37-231/319.0
ALEFQRLnsvTSREIPVEEKSVGEKPQNLHKNRFSDIIALNSCRVMLHKEHADEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIV
||.|. . . .. ... . .|| |||. .|.| . .| |.. | |||||| |. .. .. .||.| || .|..|||||. .|.. |||
evefrra...cklgvnladqtfanldqnkdknriinilafdknvvklerliGeefsdyinasfvtGyqrkdkyiaaqGPldntladfWrmiweyncstiv
MLNnlhdqvAPESSEYWPDHGATKYGHIGISVLSKQKKGDVICVKPKVTR---KKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQT-SQQQCGNVPV
.| |.||| .. |... ..| | .. . . . .... .| ... | | |. |. . .. |.. |. ... .. ..
llt......kdkcsqywplkivikeerfkvkvdsveetaeyvvrdielsedgkekdirkitqfhflGwpdvGvpdypsdlmrlvkkvrhltskenhrani
LVQC
.| |
vvhc
|
|||||||||
0046845 | (Phosphotyrosine protein) phosphatases II | 424-623 | 2.8e-49 | 163.4 | In-house | 4-212 (284) | alignment | ||
Range on Protein: 424-623
Range on HMM: 4-212/284.0
LEFQRLNSVTSREIpvEEKSVGEKPQNLHKNRFSDIIALNSCRVMLHKEHAD-EESDYINAVFLHAH-----RGRNAFIATQHPLLETVEDFWRMVTDYD
||..|.|.| . . ||. .|.||.|||..||......|| |. .. | |.|||||| ... . . ...|||||.|| .||||||||| ...
eefeellsltvkll..lslsvallpenlsknRykdilpydhsRVklksldgdledsdYinAsyvdgydldltyikkkfIatqgPlpntvedFwrmvweqn
IGTIVMLNNLHDQVAPESSEYWPDHG-ATKYGHIGISVLSKQKKGDVICVKPKVTR---KKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQQ-
. .||||..|.. . |||. | .||.. . .||...|.|... . ..|. ......|.|.|. || | ..| ....|..|..|......
vrvIVmltelvengrekcaqYwplegevltygdftvtllseevkddytvrtleltnlgytgesrtvthfhytswpdhgvppspedlleflrlvrellenl
CGNVPVLVQCR
|. |..| |.
pgggpivVHCs
|
|||||||||
subfamily_Sponge-PTP5_pd | Subfamily Sponge-PTP5 | 424-623 | 1.7e-30 | 100.9 | In-house | 10-207 (283) | alignment | ||
Range on Protein: 424-623
Range on HMM: 10-207/283.0
LEFQRLNSVTsreIPVEEKSVGEKPQNLHKNRFSDIIALNSCRVMLHKEHAdeesDYINAVFLH---AHRGRNAFIATQHPLLETVEDFWRMVTDYDIGT
| ...|. .. .| . . .| .|||. .|.. . || |. | |||||||. .. . .|..| || .|| |||.|| | .| .
lfrevlkrls...vpdldadiasadenkrknrnqeivpadqwrvelksesr....dyinavfipvsksykqdkkyiiaqsPldrtvvdfWkmvfdekita
IVMLNNLHDQVAPESSEYWPDHGATKYGHIGISVLSKQKKGDVICVKPKVTRK---KKTHEVRHLHHVSWTDkCIPKVSRSVLDLLDEVQTSQQQCGNVP
|||| .| .. . | ||| .|. .|| ... . | . . . |.| . | . |.. . .. | .. |.. |.. . |
ivmltklqedlrikCsqyWPkrGsedyGeftvtlrkettsnsfiikelllrvnssakstlllahyqvidWle.ygeqaiinslvkfnkvislqteskkgP
VLVQCR
..| |
ivvhCs
|
|||||||||
DSPc_SM00195 | 425-623 | 3e-47 | 156.5 | In-house | 5-203 (263) | alignment | |||
Range on Protein: 425-623
Range on HMM: 5-203/263.0
EFQRLNSVTSREipveEKSVGEKPQNLHKNRFSDIIALNSCRVMLHKEHADEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVML
||..|.. || . |.. .||..| .|||...|. .. || |.||. .|.|||||| .. .. ....||||.|| .|||||||||.. .. .||||
efekleestspk....etteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivml
NNLHDQVAPESSEYWPDH--GATKYGHIGISVLSKQKKG-DVICVKPKVTRKK--KTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQQCgNVPVL
.. .. . ..|||. | ...|.| . . ...|| ..| . ..| .. .|..|..... .|.|. .|. .|||.|| .|..|... ..|..
teeeengkekcdrywpeesggketfgkisvklvevekkkdeiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkksksts.sgpiv
VQCR
|.|
VhCs
|
|||||||||
PTPc_SM00194 | 425-623 | 3e-47 | 156.5 | In-house | 5-203 (263) | alignment | |||
Range on Protein: 425-623
Range on HMM: 5-203/263.0
EFQRLNSVTSREipveEKSVGEKPQNLHKNRFSDIIALNSCRVMLHKEHADEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVML
||..|.. || . |.. .||..| .|||...|. .. || |.||. .|.|||||| .. .. ....||||.|| .|||||||||.. .. .||||
efekleestspk....etteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivml
NNLHDQVAPESSEYWPDH--GATKYGHIGISVLSKQKKG-DVICVKPKVTRKK--KTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQQCgNVPVL
.. .. . ..|||. | ...|.| . . ...|| ..| . ..| .. .|..|..... .|.|. .|. .|||.|| .|..|... ..|..
teeeengkekcdrywpeesggketfgkisvklvevekkkdeiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkksksts.sgpiv
VQCR
|.|
VhCs
|
|||||||||
subfamily_PTPN13_pd | Subfamily PTPN13 | 425-622 | 9e-26 | 85.7 | In-house | 16-209 (273) | alignment | ||
Range on Protein: 425-622
Range on HMM: 16-209/273.0
EFQRLNSVTsreiPVEEKSVGEKPQNLHKNRFSDIIALNSCRVMLHKEHAdeesdYINAVFLHAHRGRNAF--IATQHPLLETVEDFWRMVTDYDIGTIV
||. |. . |... .||.| .| .|||. ... . || | .| . |||| ..... | . . ||.| || |||.|||.|| . . |.
efkelrelk....pldtcevgkkkenkdknryrnvlPydetrvklgdegg.....yinaslikvpvgkdeyeyiacqGPlPetvkdfwqmvweqkaevia
MLNNLHDQVAPESSEYWPDHGATK---YGHIGISVLSKQKKGDVICVKPKV--TRKKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQqcGNVP
|. . .. |||.. | .. . ...| ||. . . .| .. ....|| ||. |.| | .|. . ..| .. ||.. |. . |
mvtlekekgkvkchrywPesknkklkvsnrlevellkvqkldgfvvralavkdsesgesrevahlnfvkwPdhgvPssaaellqfvaevrrlqt..dagP
VLVQC
..| |
ivvhc
|
|||||||||
subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 425-623 | 4.7e-20 | 66.7 | In-house | 11-200 (267) | alignment | ||
Range on Protein: 425-623
Range on HMM: 11-200/267.0
EFQRLNSVTSREIPVeEKSVGEKPQnlHKNRFSDIIALNSCRVMLHKEHADeesdYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVML
||. .. ... . . .|..|| | .||. | . . ||.| .. . |||| ...... .||||.|| || |. ||. ...|... .||.|
efelikkisdtssti.sqsiaeknq..ernrlddnlpyddtrvilrtkeee....yinasyvegyktknafivtqdplkntitdfltvihdqkvpvivll
NNLHdqvAPESSEYWPDH--GATKYGHIGISVLSKQKKG--DVICVKPKVtRKKKTHEVRHLHHVSWTDKCIPKVsrSVLDLLDEVQTSQQQCGNVPVLV
. . .|| . | || . . .... ..| .. |. ... .|.| .. | . | . |. . | . || |..|
tkvf...tdnirlfwPPkmgqakkyqdltvehslekeendyqiitlelkf.knesahnvtlyyykkwnintnnkp..ylkplfgilaknqlengnrPlvv
QCR
.|
acs
|
|||||||||
subfamily_Cele-PTP-6_pd | Subfamily Cele-PTP-6 | 426-622 | 4.8e-19 | 63.5 | In-house | 22-216 (307) | alignment | ||
Range on Protein: 426-622
Range on HMM: 22-216/307.0
FQRLNSVTSREIPVEEKSvgekpQNLHKNRFSDIIALNSCRVMLHKEHAdeESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLN
|. | | ..|| | | .|||..|. . . .|.... . . |||| | .| . ||..| || .|. .|| |. . .. ...||
frvlakktpegvtveafs.....antdknryqdvkcqdkgrivvkfdgl..asdyihanylgiaikpkkficaqgplentqysfwamaiqekvesvimlc
NLHDQVAPESSEYWPDHGATK--YGH----IGISVLSKQK---KGDVICV-KPKVTRKKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQqcgn
.. . .||| | .|. | .. | .| |.| | . || .|. ..|| | |. .|.. . ..||. |. .
kvielakikceqywpleegqklvfgeapntisvanlgakklapdedlinvttlkvdwaqksrtiqhlqwenwpdrgvpqinltainlleavrydtn....
vPVLVQC
||.| |
.pvvvhc
|
|||||||||
subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 434-622 | 3.4e-33 | 110.3 | In-house | 9-195 (284) | alignment | ||
Range on Protein: 434-622
Range on HMM: 9-195/284.0
SREIPVEEKSVGEKPQNLHKNRFSDIIALNSCRVMLHKEHADEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNnlhdqvAP
. .. ... . .|| |||. .|.| . .| |.. | |||||| |. .. .. .|||| || .|..|||||. .|.. |||.|
klgvngtdqtfanldqnkdknrighilafdknvvklerliGeefsdyinasfitGyqrkdkyiatqGPldntladfWrmiweyncstivllt......kd
ESSEYWPDHGATKYGHIGISVLSKQKKGDVICVKPKVTR---KKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQT-SQQQCGNVPVLVQC
|.||| .. |... ..| | .. . . . .... .|. ..| | | |. |. . .. |.. |. .... .. ...| |
kcsqywplkivikeerfkvkvdsveeseeyvvrdielsedgkekdirkirqfhflgwpdvgvpdypsdlmrlvkkvrhltskenhranivvhc
|
|||||||||
subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 435-546 | 1.3e-17 | 58.6 | In-house | 32-157 (350) | alignment | ||
Range on Protein: 435-546
Range on HMM: 32-157/350.0
REIPVEEKSVGEKPQNLHKNRFSDIIALNSCRVMLH--------KEHADEESDYINAVFLHAH----RGRNAF--IATQHPLLETVEDFWRMVTDYDIGT
| | .. . | . |||...|. . || |. |.|. . .||||| .|. . | |||| || .||.||..... ..
sespsnDvilseGvelfaknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkv
IVMLNNLHDQVAPESSEYWPDHGATK
|..|... .. .||.. . .
ilsltsdvelnlekcyrYWqegsydd
|
|||||||||
subfamily_eak_pd | Subfamily eak | 435-596 | 3.2e-14 | 47.1 | In-house | 37-198 (332) | alignment | ||
Range on Protein: 435-596
Range on HMM: 37-198/332.0
REIPVEEKSVGEKPQNLHKNrFSDIIALNSCRVMLHKEHADeESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPE
. .. .|.... .....| .|. . | | . . |||| . . .| | . . | ||.|| . .||.| . .. .
dyqrllsisetarleavnrn.vvkivpydrylvrltssqln.rlGyinaslaefsevGrkyiltGiasedkvfafwqmvleqkspaivqlledvelklek
SSEYWPDHG--ATKYGHIGISVLSKQKKGDVICVKPKVTRKKKTHEVRHLHHVSWTDKCIPKVS
| |.||.. |.|.. . . |.. . . .... .||.| | . ||. .||.
sdkyfpdktreelkfGildverkefvkrniletrllelskGnethrvlhykvfGwtettlpkye
|
|||||||||
subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 436-598 | 2.4e-24 | 80.7 | In-house | 19-185 (297) | alignment | ||
Range on Protein: 436-598
Range on HMM: 19-185/297.0
EIPVEEKSVGEKPQNLHKNRFSDIIALNSCRVMLHKEHadEESDYINAVFLH--AHRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAP
| |. |. .. |.|||. ||.| .. || | . |.||||| .. .| .| || .||.|||..|.. |...|||. .| ..
eargesfssakrnsslrknryrdilatddtrvkllrvi..terdyinadyvvfpdeeadlkyilaqGplsatvddfwtlvaeqdvrvivmvaklqedGrd
ESSEYWPD--HGATKYGHIGISVLSKQKK--GDVICVKPKVTRKKKTHEVRHLHHVSWTDKCIPKVSRS
|||. . | |.. . ||. || . .. .... ||| ..|| |. .|
kcapywpsvvqerlkagdvvveflsstsdefdrviltelqliyrsesrvvrhvqflswpdhGvpsdled
|
|||||||||
subfamily_Cele-PTP-13_pd | Subfamily Cele-PTP-13 | 436-608 | 8.9e-18 | 58.9 | In-house | 23-198 (281) | alignment | ||
Range on Protein: 436-608
Range on HMM: 23-198/281.0
EIPVEEKSVGEKPQNLHKNRFSDIIALNSCRVMLHK-EHADEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPE
. | . .| ..| | .|||...| .|. || |. . .||| | .... . .| || | || |||||. . . .|||| .. . .
dppsdlctvfnqpvnnkknrylnipcldisrvqlkvkmpnknstdyihanyirspflkrgyiltqgpkketradfwrmiwqenttaivmlcqfletnrek
SSEYWPD--HGATKYGHIGISVLSKQKKGDVICVKPKVTRKKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQT
.||.| | . .. .. .| . .. . ... . .|. . | | | .|. | .| .| ....
caeyfprnahcclqfdklsvsyedstvnkslvttrlnlsyegetrlithwlwkewpdwqvpessevmlkilrkira
|
|||||||||
subfamily_PTPN5_RR_pd | Subfamily PTPN5_RR | 437-622 | 3.4e-34 | 113.2 | In-house | 14-208 (274) | alignment | ||
Range on Protein: 437-622
Range on HMM: 14-208/274.0
IPVEEKSV-GEKPQNLHKNRFSDIIALNSCRVMLHKEHADEE-SDYINAVFLHAHRG-RNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAP
.|.. . . . . .|||. .|. . ||.|..|....| |.|||| ... .. .|..||| || .||.|||||. .. |||| .|...
lPlnfdqeeldvfgsqtknryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntvadfWrmiyqeevqvivmltklkeaneq
ESSEYWPDHGAT----KYGHIGISVLSKQKKGDVICVKPKVTRKKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQQCGNV--PVLVQC
..|.||. . .||.. | | .. .. | | . .....| | . .| |. |. ...|||..||..|... . ||.| |
kCavyfPdaedyeiserygdveikvekiverndysvrklvlkylerersvkhywytdWPdhksPddantlldlvleveesreeenaklapvvvhC
|
|||||||||
0045098 | (Phosphotyrosine protein) phosphatases II | 438-623 | 2.1e-40 | 134.3 | In-house | 21-214 (278) | alignment | ||
Range on Protein: 438-623
Range on HMM: 21-214/278.0
PVEEKSVGEKPQNLHKNRFSDIIALNSCRVMlhkehadeesDYINAVFLHAHrgRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSE
.. | ... .. ||.|||..||......|| ||||| ... . ...|||||.|| .||.|||||. ...| .||||..|.. .
ipseitpalylgnldknRykdilpydhsrVk..........dYINAsyidgy..pkkfIatqgPlpstvadfwrmlwelgitvivmltelvelgrekcaq
YWPDHGATKYGHIGISVLSKQKKGDVICVKPKVT------RKKKTHEVRHLHHVSWTDKCIPKVS--RSVLDLLDEVQTSQQ------------QCGNVP
|||..| ||.. . .|| . .|.. .. .|| ....|.||| ..| | ..| . .|.|.||.... .. . .. |
ywpeggsltygdftvtllseevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllsslllldsggp
VLVQCR
||| |.
vlVHCs
|
|||||||||
subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 438-623 | 2.7e-37 | 123.3 | In-house | 32-218 (315) | alignment | ||
Range on Protein: 438-623
Range on HMM: 32-218/315.0
PVEEKSVGEKPQNLHKNRFSDIIALNSCRVMLHKEHADEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSE
.. .. |. ...| .|||. .|. |.| ||.| . .|||||| .... .|.||.| || .|.|||||| .... ||||....... .
diyrqrvaretinfkknryknilPldsarvkleviddsPdsdyinasyiksvdddkayiasqgPlkasvddfwrmvlqekvttivmvtkkqegdkikcrq
YWPD--HGATKYGHIGISVLSKQKKGDVICVKPkVTRK-KKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSqQQCGNVPVLVQCR
|||| ....| | ...|| . .| . | |||| .... | . | || ..| . |.| |. ||... .. . ..|| |
ywPdrkadsvefGsikvellsleadtdgvarkl.vtrkseesrtvtqfqftewPdkGvdkqtssllklikevkad.ngkkefsllvhcs
|
|||||||||
subfamily_Urchin-PTP-4_pd | Subfamily Urchin-PTP-4 | 438-622 | 1.4e-26 | 87.8 | In-house | 33-176 (392) | alignment | ||
Range on Protein: 438-622
Range on HMM: 33-176/392.0
PVEEKSVGEKPQNLHKNRFSDIIALNSCRVMLHKEHADEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVapesse
.. ...|..|. ||.|||. .|. ..| ||.| .|||.|| .... .|.||.| | ...|||||| . .. ||.|...|..
diypqtvaqkeinlkknryknilpydsarvkleviddipdsdylnasyipsfdnekayiasqgpnaaslddfwrmvfqenvttiamvtklkegd......
ywpdhgatkyghigisvlskqkkgdvicvkpkvtRKKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQQCGNvPVLVQC
. .... | | . | || .|| . |.| .. ||.. | |....|
..................................kgddartvaqfhftewPdkdvpkhtssllkfikevkadfGqyth.pliihc
|
|||||||||
subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 438-542 | 2.3e-09 | 31.0 | In-house | 36-156 (349) | alignment | ||
Range on Protein: 438-542
Range on HMM: 36-156/349.0
PVEEKSVGEKPQNLHKNRFSDIIALNSCRVMLHKE--------HADEE------SDYINAVFLHAHRG--RNAFIATQHPLLETVEDFWRMVTDYDIGTI
.... . | . |||..||. . ||.|.| .. | ||||| .|. | . .|||| || ||.||..... . .
eiddvilseGvelfaknrykdilPyehsrvklkkslksskvikastsesdsgklddyinanylkltrisvekkyiatqaPlPstvddfykvillngvklv
VMLNNLHDQVAPESSEYWPDH
. ||. ... || .
lsLnddkelslekcdiywqel
|
|||||||||
subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 439-623 | 3.9e-40 | 132.8 | In-house | 40-225 (297) | alignment | ||
Range on Protein: 439-623
Range on HMM: 40-225/297.0
VEEKSVGEKPQNLHKNRFSDIIALNSCRVMLHKEHADEESDYINAVFLHAHRGrnAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVApESSEY
. .. | || |..|.|...|. .| ||.|. | .|||.|| |... . .|.|| | .||.|||.|| |... ||||||..... . |
iqpqtvaekkvnfeksRYkniLPydssRvkLaivnddpdsDyvnasfvkgnkh..rlittqmPmkatvadfWamvldeqvstivmlnddnerdk.kcary
WPDHGATKYGHIGISVLSKQKKGDVICVKPKVTRKK--KTHEVRHLHHVSWTDKCIPK--VSRSVLDLLDEVQTSQQQCGNVPVLVQCR
|.|.| |..|.. . .|| ... | . .||. | ... |. ..|.| || ... .|.|.|..||. . .| . |.|| |
WsdkgvttfGdvsvvllsvsereGfikrelevtkgkakarrvvkqyqfveWPdkaverkdsassllklisevrkdfsqnaegPllvhcl
|
|||||||||
subfamily_ptpA1_pd | Subfamily ptpA1 | 439-622 | 1.2e-21 | 72.0 | In-house | 36-236 (418) | alignment | ||
Range on Protein: 439-622
Range on HMM: 36-236/418.0
VEEKSVGEKPQNLHKNRFSDIIALNSCRVMLHKEHADEESDYINAVFLHAHRGRnAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEY
| | |.| .| |||...|. .| || |.| . | |||||| .. . ||.|| || .|. |||||| . ||||. ... . |
psetsegdkkhntsknrytnilpvnhtrvqlkkiqdkegsdyinanyidgaypk.qfictqgplpntiadfwrmvwenrcriivmlsresencrikcdry
WPDH-GAT----------KYGHIGISVL--SKQKKGDVICVKPKVTRKKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQQC-----GNVPVLV
||.. | .| . .. .. . ..| . ..| . .|... . .. | |. || .. . .|| . |.| |||..|
wpeqiggeqfsiygngnevfgtysvelveviqdpereiitrnirltfegetrditqyqyegwpdhnipdhtqpfrqllhsitnrqnqiipssdrnvpiiv
QC
.|
hc
|
|||||||||
subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 440-622 | 7.8e-41 | 135.2 | In-house | 36-223 (305) | alignment | ||
Range on Protein: 440-622
Range on HMM: 36-223/305.0
EEKSVGEKPQNLHKNRFSDIIALNSCRVMLHKEHADEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEYW
| ||.| .| .|||...|. |. |..| ... ...|||||| ...........|..| || .||.||||.. .. . ||||| .| .. ||
esidvgkkeankaknrlkeitlldddriiltekeslddsdyinasyvdgykrkkkyivaqgPlkntvadfWrliveekvstivmltklveggkdkCrqYW
PDHGAT--KYGHIGISVLSKQKKGDVICVKPKVTR---KKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQQCGNVPVLVQC
|. . ..|.. . . |... | | | |.. .|... | ... .| |. .|. . |.|.|...|| .|.. .||.|| |
pesktekkefgefsvelksektasdyieRklkisiededkesrtvlqyqltdWPdhGvpqfatsllslikrvqkdqkkdkgvpllVhC
|
|||||||||
subfamily_PTPRN_pd | Subfamily PTPRN | 440-623 | 5.3e-32 | 105.7 | In-house | 46-232 (297) | alignment | ||
Range on Protein: 440-623
Range on HMM: 46-232/297.0
EEKSVGEKPQNLHKNRFSDIIALNSCRVMLHKEHADEESDYINAVFLHAHRGRN-AFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEY
. |.|.....|..||| ..... . || |..| ..|.|||||| .. | |. |.|||| || .|| |||.|| . . ||.| .|... . ..|
stkevakaeknvkknrskavlpydhsrvklkeeasaeksdyinasaildhdprapayiatqgplastvadfwqmvweqGvvvivnltrleeegvkqckry
WPDHGATKYGHIGISVLSKQKKGDVICVKP---KVTRKKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQQcGNVPVLVQCR
|||.|. |. . ..|. | |. | ....| | .|..||... .| ..|.|.. |. | . |..| |
wpdeGsevyhiyevhlvsehiwcddylvrsfylknlqtsetrtvtqfhflswpeegvPasaksllefrrkvnksyrG.rscpivvhcs
|
|||||||||
subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 440-622 | 3.9e-31 | 103.0 | In-house | 10-204 (270) | alignment | ||
Range on Protein: 440-622
Range on HMM: 10-204/270.0
EEKSVGEKPQNLHKNRFSDIIALNSCRVMLHKEHADEESDYINAVFLH-AHRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEY
.|... | .. . ||. ||. ||.|.... |... |||| ... .. ....||.. || |...||||. . .|||. .|... . . |
sesdlpeaargkklnRyadiLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerY
WPDHGAT----KYGHIGISVLSKQKKGDVICVKPKVTRKKKTHEVRHLHHVSWTDKCIPKVSR------SVLDLLDEVQTSQQQCGNV-PVLVQC
|| . . ..|.| . .||..|. | . ....| ..... | ....| |. .|. . ..| .| .|. |... . |.|| |
WpaepkekvkledgkikvlalseekeegyiltrlrleekgeerrlvHfwyntWpdhgvpreedsslstdqllkmlravrrsekeldkaePllvHc
|
|||||||||
subfamily_Sponge-PTP9_pd | Subfamily Sponge-PTP9 | 440-622 | 1.3e-26 | 88.0 | In-house | 30-233 (301) | alignment | ||
Range on Protein: 440-622
Range on HMM: 30-233/301.0
EEKSVGEKPQNLHKNRFSDIIALNSCRVMLHKEHA--DEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSE
.. .|| . .| . ||| .| .. |..|..... . .|||| .... . ...|||.| |. .|. ||||.. .. .|||. ||... .. .
ksctvglseenkalnrfknitvyddnriilkpkpnldlcqreyinasyidgysekkkfiaaqgpmkktlvdfWrliwqekpvsivmvtnlkegtkskceq
YWPDHGATKYGHIGISVLSKQKK--G-----------------DVICVKPKVTRKKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQQCGNVPV
|||. |... ..|. .... | | ||...|....| |. ..| . . . | || .|.| ||. | ||
ywpnseaeseefgpftvtlvneqvyPdfvirqlnvkiqdgsnngyierkfkvksdksswdvlqlqvtdWpqdGvvreprtvLqviddvihrqqkigggpv
LVQC
.| |
vVHC
|
|||||||||
subfamily_PTPN3_pd | Subfamily PTPN3 | 441-622 | 4.2e-35 | 116.0 | In-house | 32-215 (280) | alignment | ||
Range on Protein: 441-622
Range on HMM: 32-215/280.0
EKSVGEKPQNLHKNRFSDIIALNSCRVMLHKEhadeESDYINAVFLHAHR----GRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESS
. |. ||.||.|||. ||.. .. ||.|... |.||||| .. | .|||| || .|..|||.|| . .. .|||| .| ..
aisaarkpenlsknryrdilpydatrvklkes....etdyinanyvnmeipstglvnryiatqGPlaktatdfWqmvweqksslivmlttlverGrvkCh
EYWPDHG-ATKYGHIGISVLSKQKKGDVICVKPKVTRKK--KTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQqQCGNVPVLVQC
.|||... ..||.. . . ..... .. . ...|. . ... .| ...|.|...|. | ..|.....|.. . . . ||.| |
qyWPetedeleygefsvkcekedetksyvlrelvlkdketkeerkilqlqylaWpdhgvPddsadflefvervrklr.sgkeePvvvhC
|
|||||||||
subfamily_PTPN14_pd | Subfamily PTPN14 | 441-612 | 2.9e-26 | 87.2 | In-house | 40-218 (300) | alignment | ||
Range on Protein: 441-612
Range on HMM: 40-218/300.0
EKSVGEKPQNLHKNRFSDIIALNSCRVMLHKEHADeESDYINAVFLHAHRG--RNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEY
. |... |.| .|||| |.. . .|| | . . ...|||| ... | . .|..| || ||.|||.|| . .. |||| . ... | .|
llstaklpenaeknrfkdvlPyednrvelsptken.stgyinassikvsvggkersyivaqgPleltvqdfWqmvWeqgvqlivmlteeeedgkeksfky
WPDH----GATKYGHIGISVLSKQKKGDVICVKPKV--TRKKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQQ
.|.. ..|. .. ... . || . |. |. .| || .. |.|. .|. .. |. |.||| ...
fPkleskkktvefgkfkvttkfsedsdsvittglklkhlpskeertvwhlqytDWpdhgvPeDvkgflsyLeevqsvrrk
|
|||||||||
subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 442-622 | 8.5e-82 | 269.1 | In-house | 1-182 (250) | alignment | ||
Range on Protein: 442-622
Range on HMM: 1-182/250.0
KSVGEKPQNLHKNRFSDIIALNSCRVMLHKEHADEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPeSSEYWPD
|||..||||..|||..|||||.|.||.|.||..|.|||||||.|||....|.||||||.|| .|.|||||||.....||||||.||... ..|||
ksvakkpqnkeknryadiialdssrvvLekekgdkesdyinasflhgyderkafiatqgPlqatiedfWrmvleeksgtivmLtnLkesekt.yhqywPv
HGATKYGHIGISVLSKQKKGDVICVKPKVTRKKKTHE--VRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQQCGNVPVLVQC
.|.|||.. .|.|||....|.. | |....||..| ||.||.|.| ||..|.| ..||.||..||.||||.|| ||.|||
ekaekyGdvtvsllskeefadytkrklklskakkaderivrqlhfvvWPdkgvPevatavLellkkvqasqqqagnaPvivqC
|
|||||||||
0040439 | (Phosphotyrosine protein) phosphatases II | 442-623 | 2e-42 | 140.9 | In-house | 3-187 (249) | alignment | ||
Range on Protein: 442-623
Range on HMM: 3-187/249.0
KSVGEKPQNLHKNRFSDIIALNSCRVMLHKEHADEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEYWPD
.||...| |..|||..||......|| |. . |||||| ... . ..|||||.|| |||||||||. ...|..||||..| .|||.
ysvallpenkdknrypdilpydhsrvklsilpglflsdyinAsyidgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqywpl
HGATKYGHIGISVLSKQKKGDVICVKPKVT--RKKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQQC-GNVPVLVQCR
| ..||.. . .|| ..|.|... . ..| ......|.|.....| | .|. ..||....|.. .... . |||| |
ggsleygdftvtllsvevkddytvrtleltnlydgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleelpkggpvlVHCs
|
|||||||||
subfamily_PTPN1_pd | Subfamily PTPN1 | 442-622 | 8.7e-28 | 91.8 | In-house | 24-208 (290) | alignment | ||
Range on Protein: 442-622
Range on HMM: 24-208/290.0
KSVGEKPQNLHKNRFSDIIALNSCRVMLHKEHAdeesDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEYWPD
.. ..|.| .||. |. . .|..|.... ||||| ...... . .| || || .||. ||.|| . . ..||||.. .. .|||
treaklpenrnlnryrdvspydhsrikleradn....dyinaslveleeakrsyiltqGPlpntvdhfWqmvWeqkskavvmlnkvvekeqikcaqywPq
HG---ATKYG--HIGISVLSKQKKGDVICVKPKVTR--KKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQQCGNV-PVLVQC
. . .. .. . ..|...| . . ... ..|.|. | |...|.| .|. . |..| .|. | .| |... |
geeekellledtklkvkliseerksyytvrllelenlktqetreilhfhyttwpdfgvpespaaflkflfkvresGslssdvGpavihc
|
|||||||||
subfamily_PTPRK_pd | Subfamily PTPRK | 443-623 | 2.3e-45 | 149.8 | In-house | 36-218 (314) | alignment | ||
Range on Protein: 443-623
Range on HMM: 36-218/314.0
SVGEKPQNLHKNRFSDIIALNSCRVMLHKEHADEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEYWPDH
. | .| .|||. ||.| . .||.|. . | .|||||| .. ... .|||.||.|| |||.||||.| |.. .||||..| .. . . ..|||..
daakkdenreknrsgdilaydrsrvflitidgdpssdyinaalidsykrpaafivtqgPlqetvkdfWrlvydencasivmltelvevgrvkClkyWPed
GATkYGHIGISVLSKQKKGDVICVKPKVTR----KKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQQcGNVPVLVQCR
. . ||.| . ... . . ... .|.. .....|||......|.| .|. ...|.|. .|..||.. .. ...| |
tev.ygdikvelvetellaelvvrifrveklargqeeirevrqfqflgWpdhdvPvsatgllklvrrvkksqee.eaGrivvhCs
|
|||||||||
subfamily_PTPRA_pd | Subfamily PTPRA | 443-622 | 6.8e-45 | 148.4 | In-house | 51-235 (330) | alignment | ||
Range on Protein: 443-622
Range on HMM: 51-235/330.0
SVGEKPQNLHKNRFSDIIALNSCRVMLHKEHADEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEYWPDH
. .| .| .|||. .|. . ||.| . . |||||||| |.. .. .. |||.| |. |||||||||. ... ||||| .|... ||||.
elaskeenkeknrvvnilPydfsrvilsvkeGveesdyinasfidGykekdkfiaaqGPkeetvedfwrmiweqksativmltelkerkeekcaqywPde
GATKYGHIGISVLSKQKKGDV----ICVK--PKVTRKKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQQCGNvPVLVQC
|. ||.| ..| .. |. ..|. |. ||.||. || .| || | .| .. .|.|| .|.. .|| .. |. | |
GlvtyGnirvevedetvlvdytvrkflvqqlpdatrekksrlvrqfhftswPdvGvPfepiGmlkllkkvkklnqqsag.pivvhc
|
|||||||||
0042113 | (Phosphotyrosine protein) phosphatases II | 443-623 | 5.8e-43 | 142.4 | In-house | 2-184 (245) | alignment | ||
Range on Protein: 443-623
Range on HMM: 2-184/245.0
SVGEKPQNLHKNRFSDIIALNSCRVMLHKEHADEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEYWPDH
||...| | .|||.|||......|| | . |. |||||| . . .| . |||||.|| |||||||||. ...| |||||..... . . .|||..
svallpenkdknrysdilpydhtrvklspdggdldsdyinasyvdgyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywplg
GATKYGHIGISVLSKQKKGDVICVKPKVT--RKKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQQCGNVPVLVQCR
. ..||.. . .|| ....|... . .|| ......||.|.|...| | ..| ....||.|..|.. .....| |||| |.
esltygdftvtllseehlddytvrtlevtnlgddesrevihyhylpwpdhgvpdllellldflefvrkalaedsngpvlVHCs
|
|||||||||
subfamily_PTPN9_pd | Subfamily PTPN9 | 443-612 | 5.1e-38 | 125.8 | In-house | 35-208 (297) | alignment | ||
Range on Protein: 443-612
Range on HMM: 35-208/297.0
SVGEKPQNLHKNRFSDIIALNSCRVMLHKEHADEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEYWP--
. ... ||.|||..|.. ... ||.| |.. ||.|||||| |. .. ..|||||| || .||.|||||| . .. .||| . .. ..|||
lasklranleknrytdvlcydetrvvlakvdedeasdyinanfvdGykqkkafiatqGplkktvsdfWrmvWeqevlvivmttrvvergrlkcgqyWple
DHGATKYGHIGISVLSKQKKGDVICVKPKVT--RKKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQQ
.. ....|.. .|... ... | . ... ..... .| | .|| | .|. . |.||.|..|. | .
eessaefgdlsvsnveveeeedykvrvleiknvkteesrkvthfqflsWPdyGvPssaaslldvlekvrekqal
|
|||||||||
subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 443-623 | 1.2e-37 | 124.2 | In-house | 36-217 (515) | alignment | ||
Range on Protein: 443-623
Range on HMM: 36-217/515.0
SVGEKPQNLHKNRFSDIIALNSCRVMLHKEHADEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEYWPD-
.| .. | .|||. .|. ..| || | . . .|||.|| .... .|.||.| |. .|.||||.| .... ||.|...|... ..||||
tvaqeeinfkknryknilPydsvrvklevindnPhsdyfnasyipsfdndkayiasqgPnkasvddfWrlvlqenvttiamvtklkegdkikcgkyWPdk
-HGATKYGHIGISVLSKQKKGDVICVKPKVTRKKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQQCGnVPVLVQCR
. |.|.| ....| . .. | | .|.. .... | | | || .|| ..|.| |. ||.....| |... |
pgdsvkfGsikvelvsleactggikrkltvlkgddsrtvtqfhfteWPdkGvpkhtssllklikevkadhgqyt.hpliihcs
|
|||||||||
subfamily_Sponge-PTP3_pd | Subfamily Sponge-PTP3 | 443-499 | 5.7e-08 | 26.8 | In-house | 41-94 (95) | alignment | ||
Range on Protein: 443-499
Range on HMM: 41-94/95.0
SVGEKPQNLHKNRFSDIIALNSCRVMLHKEhadEESDYINAVFLHAHRGRNAFIATQ
.|| |. |||| .|. .. ||.| .||||||.|. . .|..||.|
tvgsseanipknrflnifpydatrvvlttk...rdsdyinacfvdgyarkncyiaaq
|
|||||||||
subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 444-623 | 1.1e-39 | 131.2 | In-house | 43-220 (315) | alignment | ||
Range on Protein: 444-623
Range on HMM: 43-220/315.0
VGEKPQNLHKNRFSDIIALNSCRVMLHKEHADEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEYWPDHg
| | .| .|||. .||| . || | |..|||.|| |. . .. .||.| |. ..|.||||.| ..|||.||||.|| .. . .||||.
vakkienkqknryiniiaydksrvqlpllendphsdyvnanfidGynkkrryiaaqgpnvasvkdfwrlvfeedigkivmltnlvegekrkaekywpdk.
ATKYGHIGISVLSKQKKGDVICVKPKVTRKKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQQCGnVPVLVQCR
||.| .. |.... .. . |. ... .|| ||. || | .|| . ....| |. ... ...| |.
kviyGkitvtrkseevnteytvrtlsvvfgdnirevvqlhytswpdmgvpkytiplmnlirtvkqhhtnsv.gaivvhcs
|
|||||||||
0037934 | (Phosphotyrosine protein) phosphatases II | 444-624 | 2.8e-38 | 127.3 | In-house | 4-187 (243) | alignment | ||
Range on Protein: 444-624
Range on HMM: 4-187/243.0
VGEKPQNLHKNRFSDIIALNSCRVMLhkehadEESDYINAVFLHAHrGRnaFIATQHPLLETVED----FWRMVTDYDIGTIVMLNNLHDQVAPESSEYW
.. .|.||.|||.|||.... || | | |||||| . .| .||||.|| ||||| ||||. ...|..||||..| . . .||
iallpenlsknrysdilpydhsrvkl......egsdyinanliyvt.pr..liatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqyw
PdhGATKYGHIGISVLSKQKKGDVICVKPKVTR---KKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQQ-------CGNVPVLVQCRY
| | . ||.. . .|| . ..|.. . .... .. |..|.|.|...| | ..| ..||.||||.. ... .. |||| |.
p..gevtygdftvtllseehlddytvrtlllenldlddltrlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsa
|
|||||||||
0049772 | (Phosphotyrosine protein) phosphatases II | 444-623 | 4.2e-22 | 74.7 | In-house | 40-220 (314) | alignment | ||
Range on Protein: 444-623
Range on HMM: 40-220/314.0
VGEKPQNLHKNRFSDIIALNsCRVMLHKEHADEeSDYINAVFLHAHrgrNAFIATQHPLLETVEDF----------WRMV--TDYDIGTIVM--------
|. .. | .|||. ||. . .||.|.... . |||||| ... . ..|||||.|| .||.|| |||| |... .|||
vadlflnrdknryldilpad.nrvilpglpvsg.sdyinasyvdgf...lkfIatqgpleitvvdfreepvlyyngwrmvlrgdlnvrdivmsrdevlad
-------------LNNLHDQVapesseywpdhgaT---------KYghigisvlskqkkgdvicvkpKVT--RKKKTHEVRHLHHVSWTDKCIPkVSRSV
|..| . ... ... .... ..... ..| . | .. .
elsrLdaAlgKtpllildgng.............neptaadlellk.....................eelydpelferlgikylripvpDgsap.lledf
LDLLDEVQTSqqqCGNVPVLVQCR
...|. ... . |||| |.
deflefieea...dkggpvlvHCk
|
|||||||||
subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 446-622 | 3.4e-23 | 76.9 | In-house | 34-217 (287) | alignment | ||
Range on Protein: 446-622
Range on HMM: 34-217/287.0
EKPQNLHKNRFSDIIALNSCRVMLHKEhADEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEYWPD-HGA
|. . .|||..|.. .. ||.| .| .. |||||| .. ... .||||.| |. || ||||.| . ..... .. . .|||. .
eelaavkknryadvlPiddtrvllsae.gelGsdyinanyvasytddeafiaaqgPiaatvrdfwravletrsasvitmtreveearlkcykywPerevP
TKYGHIGISVLSKQKKGDVICVKPKVTRKKKTHE---VRHLHHVSWTDKCIPKV----SRSVLDLLDEVQTSQQQCGNVPVLVQC
. | . .|....| .|. . .|.| |. |. .|| || .. | ||| . .. ... . |..| .
mrvGGysvvlldydikePeygvralrlidletrearvvkqldllswPdkvlaPtavglirfvldvkqhielardasevGPlvvhd
|
|||||||||
subfamily_Sponge-PTP4_pd | Subfamily Sponge-PTP4 | 446-547 | 8e-13 | 42.6 | In-house | 92-186 (244) | alignment | ||
Range on Protein: 446-547
Range on HMM: 92-186/244.0
EKPQNLHKNRFSDIIALNSCRVMLHKEHAdeESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHdqvapESSEYWPDHGAT
.|.| .||| . . .. || | | |||| |. .| ||||| .| |||.|. . . .|.| . | |||||
fnpnnswknregaglpfdfnrvplskgsm..gntyinasfvgclgrtaeyiltqhpladtsmdfwkmmlerhvnvlvvlgsve.....eedeywpdsepl
KY
..
ew
|
|||||||||
subfamily_Cele-PTP-17_pd | Subfamily Cele-PTP-17 | 446-524 | 2.8e-11 | 37.5 | In-house | 33-116 (347) | alignment | ||
Range on Protein: 446-524
Range on HMM: 33-116/347.0
EKPQNLHKNRFSDIIALNSCRVMLHKEH-----ADEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVML
| ..| ||| | .. ||.| |. ||. |||| .. .. .| ||.|| .|| |||.||. . .| .
ewekslsknrskdvklidatrvvlspeksknsraddvetyinashikfdnaskeyiltqyplpdtvrdfwkmvsvtkvtqvvti
|
|||||||||
subfamily_Sponge-PTP6_pd | Subfamily Sponge-PTP6 | 447-623 | 5.8e-27 | 89.2 | In-house | 45-220 (439) | alignment | ||
Range on Protein: 447-623
Range on HMM: 45-220/439.0
KPQNLHKNRFSDIIALNSCRVMLHKEHADEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVApesseYWPDHGATK
. . |||. |. |.. ||.|.. | |||| ... . . .|||| | ||..||||.| . ||||| || . ||| . .
qeydqtknrykdvgafdhtrvtlqeipgvphshyinanyikGyyddklyiatqgpkkettddfwrlviekktvtivmltnlvesyk.....ywpsdaevc
YGHIGISVLSKQKKGDVICVKPKVT----RKKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQQCGNVPVLVQCR
|| | . | . . . . || . .| . | ..|...| || .| . |||.| ....... ||.|.|
ygdiavrvdrnielpnyvirgfkvfnerdttekertvlqfhyiawpdknvpaqashvldflrainsandkeeygpvvvhcs
|
|||||||||
subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 447-622 | 8.5e-23 | 75.8 | In-house | 5-181 (239) | alignment | ||
Range on Protein: 447-622
Range on HMM: 5-181/239.0
KPQNLHKNRFSDIIALNSCRVMLHKEHADEESDYINAVFLHAHRGR-NAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEYWPDHgAT
| | |||...|.. . ||.| | | |||||| .|. . | .|.|||| . . |||||. . |||| | . . .|||| ..
krvnkaknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpds.ts
KYGHIGISVLSKQKKGDVICVKPKVTRKKKTHE--VRHLHHVSWTDKCIPKVSRSVLDLLDEVqTSQQQCGNVPVLVQC
|| . ... . | | ... .| | | . | | || .|. . .|| | .. | . | | ...|
kycnlrvtlrktevfadyiirtfvmsqvgqteeryvyqyhftvwpdkgvpqyatavlglrrki.tkdslpgarpwvihc
|
|||||||||
subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 447-622 | 9.3e-23 | 75.6 | In-house | 4-180 (239) | alignment | ||
Range on Protein: 447-622
Range on HMM: 4-180/239.0
KPQNLHKNRFSDIIALNSCRVMLHKEHADEESDYINAVFLHAHRGR-NAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEYWPDHgAT
| | |||...|.. . ||.| | | |||||| .|. . | .|.|||| . . |||||. . |||| | . . .|||| ..
krvnkaknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpds.ts
KYGHIGISVLSKQKKGDVICVKPKVTRKKKTHE--VRHLHHVSWTDKCIPKVSRSVLDLLDEVqTSQQQCGNVPVLVQC
|| . ... . | | ... .| | | . | | || .|. . .|| | .. | . | | ...|
kycnlrvtlrktevfadyiirtfvmsqvgqteeryvyqyhftvwpdkgvpqyatavlglrrki.tkdslpgarpwvihc
|
|||||||||
subfamily_Cele-PTP-18_pd | Subfamily Cele-PTP-18 | 447-611 | 1.7e-17 | 58.1 | In-house | 45-220 (305) | alignment | ||
Range on Protein: 447-611
Range on HMM: 45-220/305.0
KPQNLHKNRFSDIIALNSCRVMLHKEHAdeeSDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEYWPDHG--A
. |. .|||. |. |. || |. .|| | .. . . || || || .| ||| | . . .| || || .. | .||.. .
eaqeagknrykdvgcldnnrvklegpwp...heyihanyvstptnpkrfictqaplektcadfwymclqdkveaifmlcnllekgakkcleyfaskdkdv
TKYGHIGISVLSKQKKGDVIC----VKPKVTR--------KKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQ
.. | . | . . | |||. .|.. | | | . | |. .| ..|.|| . ..|.
lefeekgqkisvkfessvtlkfrkdakakvtetvlviegpgekarkvthyhwidwpdrgvpaadlailellekarpskg
|
|||||||||
subfamily_egg_pd | Subfamily egg | 447-595 | 2.3e-15 | 51.1 | In-house | 37-187 (307) | alignment | ||
Range on Protein: 447-595
Range on HMM: 37-187/307.0
KPQNLHKNRFSDIIALNSCRVMLHKEHADEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQvaPESSEYWPDHG--A
. ||.| | . .|.|| |. .. |.| | .. . | || .| || .||.|||||| .. ||||. . . ||| .
sdnnlekarskrvhckdssrvklelrrGqylddfihanrvkGkpllnefilaqaplkntvddfwrmvfqeevqyivmltsrkes..erceyywpkaesds
TK--YGHIGISVLSKQKKGDVICVKPKVTRKKKTHEVRHLHHVSWTDKCIPKV
. | . | | ..| | . |. .| |.| | . . .|
lvtvpGslrienlkvdskadplfrvtklklvGgddeerflehwqgdvnnssdv
|
|||||||||
subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 449-622 | 5.6e-23 | 76.4 | In-house | 2-179 (237) | alignment | ||
Range on Protein: 449-622
Range on HMM: 2-179/237.0
QNLHKNRFSDIIALNSCRVMLHKEHADeeSDYINAVFLHAHRGR-NAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEYWPDHG-ATK
.| |||...|.| . .||.|. .. |||||| .|. | . .||.| || . .|||.|| . |||| | .. .|||. .
enkiknrygnivaydhsrvvlkgagsg..sdyinatylkgfdgtpkkyiaaqgplesscddfwqmvwqekcsvivmltgliegnelkchkywpstdqpaa
YGHIGISVLSKQKKGDVICVKPKVTRKKKTHEVRHLH---HVSWTDKCIPKVSRSVLDLLDEVQT-SQQQCGNVPVLVQC
|| . .|. |.. | .... . .||| .| || |. .|. . ..| . .. |. | .. |
ygvltvslkkkeefsdytvrslllskrltlkevrlihqyqftswpdrgvpqqtaallrfrkniinrsphvsesgpwiihc
|
|||||||||
subfamily_Cele-PTP-8_pd | Subfamily Cele-PTP-8 | 449-623 | 2.6e-22 | 74.2 | In-house | 42-212 (288) | alignment | ||
Range on Protein: 449-623
Range on HMM: 42-212/288.0
QNLHKNRFSDIIALNSCRVMLHkehaDEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEYWPDHG--ATK
.| ..|. .. . .|| |. |. ||.| . ... .. .| .| || |.| .|.|. . |. ||||..| .. ..| ||.| . ...
anptrdryenlprcditrvkls....ddpdfyiaanvvssakykrrlicaqaPlngtieelWkmllesdveyivmlcellekGkeksaeyfPsklGekar
YGHIGISVLSKQKKGDVICV--KPKVTRKKKTHE-VRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQqcgnvPVLVQCR
.|.. | |.. | . . ..... ... |..|| | |...|. | | ||. ... |. |..|...
igrlctvvkkkradidklvkvsllriskegeekvivkilhlleWdddgvPenylsplrllevlkslqk.....Pivvhss
|
|||||||||
subfamily_Cele-PTP-16_pd | Subfamily Cele-PTP-16 | 449-524 | 4.1e-11 | 37.0 | In-house | 46-114 (303) | alignment | ||
Range on Protein: 449-524
Range on HMM: 46-114/303.0
QNLHKNRFSDIIALNSCRVMLHkehadeESDYINAVFLHAHRGRNAfIATQHPLLETVEDFWRMVTDYDIGTIVML
.|..|||| |.| |. .| | .| || | .|. . ..| | || || | |||.|. . . ...|
knmdknrfvdvicldhskvkls......dssyihasyleldsskka.iltqlplshtaadfwqmiieqkvkcvlll
|
|||||||||
subfamily_Cele-PTP-4_pd | Subfamily Cele-PTP-4 | 449-540 | 1.9e-06 | 21.5 | In-house | 50-139 (302) | alignment | ||
Range on Protein: 449-540
Range on HMM: 50-139/302.0
QNLHKNRFSDIIALNSCRVMLHKEhadeESDYINAVFLHAHRGRNAFIATQHPLLETV---EDFWRMVTDYDIGTIVMLNNLHDQVApESSEYWP
.||.||. |. .|.| .| |..| . .|.|| .. .. | .| | .... |.||||| . | ..|.| . ||..|
knlkknqsedvpildsnlvkleae....pdsyvnaskvevPeltrsiilaQlpkvdsedsveeFWrmvfqekivsvvilvgeeelkk.tlselfp
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 450-623 | 1.3e-43 | 144.5 | Pfam-A | 1-178 (235) | alignment | ||
Range on Protein: 450-623
Range on HMM: 1-178/235.0
NLHKNRFSDIIALNSCRVMLhkEHADEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEYWP--DHGATKY
|..|||..||.. .. || | .. ...|||||| ... .. ..|||||.|| .|.|||||||..... .||||..| .. . ..||| ... ..|
nkkknRykdilpydktrvkl..kgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeeslty
GHIGISVL-SKQ-KKGDVICVKPKVTRKKKT---HEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQqQCGNVPVLVQCR
|.| . . ... .. ... | ... ||. .||..||. .|.|...|. ..|.|||...|..|. . . ||.|.|
gdikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkveksk.eaksgpvvVhCs
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 450-623 | 1.3e-43 | 144.5 | In-house | 1-178 (235) | alignment | ||
Range on Protein: 450-623
Range on HMM: 1-178/235.0
NLHKNRFSDIIALNSCRVMLhkEHADEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEYWP--DHGATKY
|..|||..||.. .. || | .. ...|||||| ... .. ..|||||.|| .|.|||||||..... .||||..| .. . ..||| ... ..|
nkkknRykdilpydktrvkl..kgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeeslty
GHIGISVL-SKQ-KKGDVICVKPKVTRKKKT---HEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQqQCGNVPVLVQCR
|.| . . ... .. ... | ... ||. .||..||. .|.|...|. ..|.|||...|..|. . . ||.|.|
gdikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkveksk.eaksgpvvVhCs
|
|||||||||
0041856 | (Phosphotyrosine protein) phosphatases II | 450-624 | 3e-24 | 81.0 | In-house | 1-118 (182) | alignment | ||
Range on Protein: 450-624
Range on HMM: 1-118/182.0
NLHKNRFSDIIALNSCRvmlhkehadeESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNnlhdqvapeSSEYWPDHGatkygh
||.|||.|||. . | .||||| .. . . |||||.|||.||.||.||. ...|.|||.|. . |||..
nldknrysdilpydhsr..........dldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlt.........eelywpell......
igisvlskqkkgdvicvkpkvtrkkkTHEVRHLHHVSWTDKCIPKvSRSVLDLLDEVQTsqqqcGNVPVLVQCRY
.... ......| | ..| ...||...||. . |||| |..
..........................erlgiqylylpwpDhgvpd.ldelldfieevle.....eggpvlVHCsa
|
|||||||||
subfamily_Cele-PTP-10_pd | Subfamily Cele-PTP-10 | 450-622 | 4.7e-16 | 53.3 | In-house | 55-228 (305) | alignment | ||
Range on Protein: 450-622
Range on HMM: 55-228/305.0
NLHKNRFSDIIALNSCRVMLHKEHadeESDYINAVFLHAHR-GRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEYWPDHGATK-Y
. |||..|. . . | |.| |||| | .. . . ||..| || .|...|| || . . |||| . . ..||| |
aitknryqdvpcqdqsavkldkps...psdyihanyvgcpmipekrficaqgpldqtidefwwmviqnkveqivmlcktvelgklkcaqywpaaqgekle
GHIGISV--LSKQK----KGDVICVKPKVTR-KKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQqqcgnVPVLVQC
. || | .| | .. ..| ... ||||. | |. .| . . |.|| .. |. ||..|.|
lksgivvenvsgskpmerdaeiqitllnltysgdqkmsvrhlqwtewpdrgvppckltslellsairgsk.....vpivvhc
|
|||||||||
subfamily_Cele-PTP-15_pd | Subfamily Cele-PTP-15 | 450-622 | 1.4e-13 | 45.4 | In-house | 35-210 (285) | alignment | ||
Range on Protein: 450-622
Range on HMM: 35-210/285.0
NLHKNRFSDIIALNSCRVMLhKEHadeESDYINAVFLHA-HRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEYWPDHG--ATK
| ||..|. ... ||.| |.| . ||| | ... . ....|.|| || ||. |||.|. . | ..|| | . . . |.|.. |
npdlnryadvrcieetrvvl.knh...drdyihaswmrmpgkdqstyittqgplpetlsdfwhmiyqekiayvlmlctlfeggvekcalyypeklgevvk
YGHIGISVLSKQKK---GDVICVKPKVTRKKKTHEVRHLHHV---SWTDKCIPKVSRSVLDLLDEVQTSQQQcgNVPVLVQC
.|. |.. ... | .. . . . | .. || | |. |. .| ...| |. . . . |. |.|
fgkyeitlteckeeaiagtilnaltvintedasseplymnhvqvpwwpdqlapedarpmielykwvkkvnpk..ekpicvhc
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 451-609 | 8.1e-17 | 55.9 | In-house | 29-193 (319) | alignment | ||
Range on Protein: 451-609
Range on HMM: 29-193/319.0
LHKNRFSDIIALNSCRVMLHKEHADEESDYINAVFLHAHR-GRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEYWPDH----GAT
|.|. ... | ||.|.. |... |..| .. .. .| .||.| .| .. ||||.| . .|| | .|... .||.| . .
kdksrvinvvPlPetrvvlqrigdddkdeyldasyvrGyddapnsyiaaqvsledsssdfwrtvweqqsrvivqltdlselGikvcaeylPtketldnts
KYGHIGISvLSKQKKGDVICVKPKVTRKKKTHEVRHLHHV--SWTDKCIPKVSRSVLDLLDEVQTS
||.| .. | ... .| . . .. . .| |.| | | . .| .... .| ||..|
lyGdilvt.lkgrevkdryaistlllkrvdkeesrelthywykwleaevPaeeaaliamllevrss
|
|||||||||
subfamily_Cele-PTP-11_pd | Subfamily Cele-PTP-11 | 454-610 | 9.8e-07 | 22.8 | In-house | 47-209 (312) | alignment | ||
Range on Protein: 454-610
Range on HMM: 47-209/312.0
NRFSDIIALNSCRVMLhkehADEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEYWPD---------HGA
||. .| . | | | .| || | |.. . |..|| || .|. ||... .|..| . .. . ....| | |
nrypniqcwdrgrftl....agdenfyihanfvkictkperfvctqgplentcthfwqlalslgstsiillcgfvedgsekcakyisdivgfvdledhrv
-TKY-GHIGISVLSKQKKGD-VICVKPKVTrkKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQ
|.| | | ||.| |. | | | . . | || |. .| . | || |. .
yteycteieiggkskdkithrvlkvvvkat..gqesklnhyqwaswpdhgmpdscdtalrllsavkkdk
|
|||||||||
subfamily_Cele-PTP-1_pd | Subfamily Cele-PTP-1 | 462-622 | 6e-11 | 37.0 | In-house | 30-198 (290) | alignment | ||
Range on Protein: 462-622
Range on HMM: 30-198/290.0
LNSCRVMLHKEHADEESDYINAVFLHAHRGRnAFIATQHPLLET-------VEDFWRMVTDYDIGTIVMLNNLHDQVAPE----SSEYWPDHGA--TKYG
.. ||.|. .||| | .. | ..|.|| |. .. .|.|| |. . . .||| . ... | ..| |.. |..
veatrvvLkgygkrfnddyiHAnrvtcpngl.rliltqsPqekitekrnStiekfwwmakqEkvkqvVmlcefeeksantslfaCakYvpesvgeelkfk
HIGISVLSKQKKGDVICVKPKVT-RKKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQqqcgnVPVLVQC
. .. || |. ||. . |. ... . | | ..|.. ... ....|.|.. |..|. ||.| |
gltvkCkskekeddvetRelvvkfddeeeftvtHsllkgWnklnvqedtktllsliqkvkask.....tpvivHc
|
|||||||||
0044763 | (Phosphotyrosine protein) phosphatases II | 464-623 | 4.5e-13 | 44.7 | In-house | 4-118 (178) | alignment | ||
Range on Protein: 464-623
Range on HMM: 4-118/178.0
SCRVMLHKEHADEESDYINAVFLHAHrgrnaFIATQHPLletvEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEYWPDHGAtkyghigisvlskqkkgdv
.|| |.. | ||||||.. . ......| .|..... ...|..||.|.. ... .|||.
rtrvllsnleglersdyinaseilpg.....lylgslpp....addlellkelgithivnlteelelgflkcdpywpeeag...................
icvkpkvtrkkkthevRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQQCGNvPVLVQCR
. .|. . | . | ... .|.... ... ....|. |||| |.
................iqylhipipDhgvpdllehflefvefieealdekgg.pvlVHCs
|
|||||||||
0046846 | (Phosphotyrosine protein) phosphatases II | 471-623 | 2.9e-18 | 61.7 | In-house | 5-117 (176) | alignment | ||
Range on Protein: 471-623
Range on HMM: 5-117/176.0
KEHADEESDYINAVFLHAHRgrnaFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEYWPDhgATKYGHigisvlskqkkgdvicvkpkv
. . |. .||||| .. .| .||||.|| .|..||..|. ...|...|.|..... |||. .|.|.
llgldldldyinanlilgsr....piatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpe..leklgi.....................
trkkkthevrHLHHVSWTDKCIPKVsRSVLDLLDEVQTSQQQcgNVPVLVQCR
. .|. | | ..| . .|.||..... ... . |||| |.
..........qylhlpwpDhgvpdl.elllellefirealke..ggpvlVHCs
|
|||||||||
0043147 | (Phosphotyrosine protein) phosphatases II | 475-623 | 6.7e-22 | 73.4 | In-house | 2-108 (172) | alignment | ||
Range on Protein: 475-623
Range on HMM: 2-108/172.0
DEESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLhdqvapesseywpdhgatkyghigisvlskqkkgdvicvkpKVTRKK
|| |||||| .|. .. . ||||| || .|..|||||. ...|..||.|..| .....
degsdyinasyldlyyipdrfiatqgplrntladfwrmlkelgithivnltel.........................................lydpel
KTHEVRHLHHVSWTDKCIPkVSRSVLDLLDEVQTSQQQCGNVPVLVQCR
.... ......| | . | .. .|..|. ... .... . |||| |.
lerlgiqylylpwpDhgvp.llellleflefidellalspggpvlVHCs
|
|||||||||
subfamily_Sponge-PTP-4_pd | Subfamily Sponge-PTP-4 | 477-558 | 4.3e-09 | 30.8 | In-house | 12-88 (130) | alignment | ||
Range on Protein: 477-558
Range on HMM: 12-88/130.0
ESDYINAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHdqvapESSEYWPDHGATKYGHIGISVLSKQ
. .|||| |. . .. ||||| .| |||.|. . . .|.| . | ||||| .. | | . .
gntyinasfvGllgrtaeylltqhpladtsmdfwkmmleryvnvlvvlgsve.....eedeywpdsePlewyeediivtltd
|
|||||||||
0036282 | (Phosphotyrosine protein) phosphatases II | 478-624 | 2.2e-21 | 71.8 | In-house | 2-113 (174) | alignment | ||
Range on Protein: 478-624
Range on HMM: 2-113/174.0
SDYINAVFLHAHRGRNAFIATQHPLLetvedFWRMVTDYDIGTIVMLNNLHDQVAPESSEYWPDhgatkyghigisvlskqkkgdvicvkpkvTRKKKTH
|||||| .|. .. . .||.|.|| ||.|. ...| |.|||.... |||. .|. ..
sdyinaspldlsyitprliagqgpla.....fwemlkelgittvvmlleekelglykcinywpe.............................lredler
EVRHLHHVSWTDKCIPKVSRsVLDLLDEVQTSQQQCGNVPVLVQCRY
.. ..... | | . | .| .|.....|.. ...... |||| |.
lgiqylylpwpDhgvpdlsi.llefvkfveealsedpggpvlVHCsa
|
|||||||||
0051429 | (Phosphotyrosine protein) phosphatases II | 478-623 | 5.1e-21 | 71.0 | In-house | 4-158 (272) | alignment | ||
Range on Protein: 478-623
Range on HMM: 4-158/272.0
SDYINAVFLHAHRG---RNAFIATQHPLLETVEDFWRMvTDYDIGTIVMLNNLHDQVAPESSEYWP------------DHGATKYGHIGISVLSKQKKGD
|.|||| .. . .........|| |..||||. ...| |||.| ... . . . ||| .. ||.. . .||.. . |
sgyiNardvggygrvvkpgrlyrsggplpltaadfwrl.kelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseellld
VICVKPKVT---RKKKTHEVRHLHHVSWTDKCIPKvsRSVLDLLDEVQTsqqqcgNVPVLVQCR
.|. . .| ....||.|||. .| | ..|. ..|.||..... . |||| |.
yilrellltlllsagearevmhlhytdwpdhgvpq..eallellellld......ggpvlvHCs
|
|||||||||
0051082 | (Phosphotyrosine protein) phosphatases II | 478-624 | 1.1e-13 | 46.6 | In-house | 3-101 (151) | alignment | ||
Range on Protein: 478-624
Range on HMM: 3-101/151.0
SDYINAVFLHAHrgrnaFIATQHPlletVEDFWRMVTDYDIGTIVMLNNLHDQVapESSEYWPDHGatkyghigisvlskqkkgdvicvkpkvtrkkktH
|||||. .. . ......| .||.... ...| |||.|.... ||.|..| .
sdyinfsyvtgg.....lyrsggp....ladflellkelgiktivnlrseeerg..ycpeylpelg.................................i
EVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTsqqqCGNVPVLVQCRY
||.|.. ..|.| .| .||..|.... ..| |||| |.
evlhipildwpdpglplsfdavleflellld....kkngpvlvHCsa
|
|||||||||
subfamily_Cele-PTP-19_pd | Subfamily Cele-PTP-19 | 481-622 | 1.9e-17 | 58.0 | In-house | 78-221 (301) | alignment | ||
Range on Protein: 481-622
Range on HMM: 78-221/301.0
INAVFLHAHRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEYWPDHGATK--YGHIGISVLSKQK------KGDVICVKpKVTR
| | .. .. . ||||| || .| |||| |.. ||. .|||| . .. .|| | . . | | | . .|.. . . |. |.
ihanwiptsGhphrfiatqgPlkntsedfwamlvqydvekivmlgqkvekleekceeylpvkisekldigrfkikiknkelilnkkiskrtleve.dstg
KKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQqcgnvPVLVQC
| .|. | | ...|||. .|| . ||.. |. |.. |..|.|
kfatrtvthyqysewtdrgvPkshaelfdlmelvkksek.....Pivvhc
|
|||||||||
subfamily_Anemone-PTP-3_pd | Subfamily Anemone-PTP-3 | 489-623 | 1.8e-17 | 58.2 | In-house | 1-143 (199) | alignment | ||
Range on Protein: 489-623
Range on HMM: 1-143/199.0
HRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEYWP--DHGATKYGHIGISVLSKQKKGDVI----CVKPKVTRKKKTHEVRHL
|.|. .||||||| ||. |||.|| . | |||.|. . . . ||| . |..||| . ... . | | . ..| | |. |
hkgqrryiatqhplretmadfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishy
HHVSWTDKCIPKVSRSVLDLL--DEVQTSQQQCGNVPVLVQCR
|| .| |.|. | .. || .| . ||.|.|
qftswkekttpnvalfvgfvvasrevskkyeqekdapvivhcs
|
|||||||||
0049260 | (Phosphotyrosine protein) phosphatases II | 489-624 | 2.7e-16 | 55.1 | In-house | 5-98 (152) | alignment | ||
Range on Protein: 489-624
Range on HMM: 5-98/152.0
HRGRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEYWpdhgatkyghigisvlskqkkgdvicvkpkvtrkkkthevrHLHHVSWT
.. ..|||||.|. .|..|||||. ...|.|||||..|.. . .|. . .|. |
yampfefiatqgpgpntladfwrmlkelgittivmltellelgklkceqyi.........................................qylhlpwp
DKCIPKVSRSVLDLLDEVQTSqQQCGNVPVLVQCRY
| . |. | .|.||. .. .. . |||| |..
Dhgvpdlsqlllflllfiekl.aldkggpvlVHCsa
|
|||||||||
subfamily_Nvec-PTP-3_pd | Subfamily Nvec-PTP-3 | 491-623 | 6.9e-17 | 56.3 | In-house | 2-142 (198) | alignment | ||
Range on Protein: 491-623
Range on HMM: 2-142/198.0
GRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEYWP--DHGATKYGHIGISVLSKQKKGDVI----CVKPKVTRKKKTHEVRHLHH
|. .||||||| ||. |||.|| . | |||.|. . . . ||| . |..||| . ... . | | . ..| | |. |
gqrryiatqhplretladfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyqf
VSWTDKCIPKVSRSVLDLL--DEVQTSQQQCGNVPVLVQCR
|| .| |.|. | .. || .| . ||.|.|
tswkekttpnvalfvgfvvasrevskkyeqekdapvivhcs
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 492-551 | 3.4e-15 | 50.3 | In-house | 235-292 (440) | alignment | ||
Range on Protein: 492-551
Range on HMM: 235-292/440.0
RNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHDQVapeSSEYWPDHG-ATKYGHIG
.||||||| || || ||||.| || | ||.|||.| |. | ||| . .| .
knafiatqmpldstvldfwrlvhdyristiimlnqlndkt...csiywpvntrsvtfgpft
|
|||||||||
subfamily_Cele-PTP-9_pd | Subfamily Cele-PTP-9 | 497-611 | 3.7e-12 | 40.9 | In-house | 39-150 (255) | alignment | ||
Range on Protein: 497-611
Range on HMM: 39-150/255.0
AtqhplleTVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEYWPDHGATKYGHIGISVLSKQKKGDVIC----VKPKVTRKKKTHEVRHLHHVSWTDKCI
||. |.... . ..||| ..... . |.|.| | ..| . . ||. . ....|||||.|.| .. | .|
l.......tvdkfyqtivqtktevvvmlcdfaeegvekcssyfplekdeklkladvnvtttkssadvvlrtleitstlgekkkthtvkhysykGWiekna
PKVSRSVLDLLDEVQTSQQ
|. .| .| .| |. |.
Pelareilnilkvvrdsks
|
|||||||||
subfamily_hpo-7_pd | Subfamily hpo-7 | 497-610 | 2.7e-11 | 37.9 | In-house | 42-155 (263) | alignment | ||
Range on Protein: 497-610
Range on HMM: 42-155/263.0
AtqhpLLETVEDFWRMVTDYDIGTIVMLNNLHDQVAPESSEYWPDHGATKYGHIGISVLSKQKKGDVICVKPKVTR----KKKTHEVRHLHHVSWTDKCI
|..|.. |.... ..||| . ... . |.|.| | ..| . . . ||. ... |||||.|.| .. | .|
l....lvqtidkfyqtivqtktevvvmLcDfneegvekcssyfPlekdekqklanvnvcttkvqsdvllktlellstlgeKkkthtvkhysykgWieknd
PKVSRSVLDLLDEVQTSQ
|. .|..| .|. .. |.
pelareilnilkvarnsk
|
|||||||||
0048179 | (Phosphotyrosine protein) phosphatases II | 552-624 | 1.9e-06 | 23.2 | In-house | 22-92 (144) | alignment | ||
Range on Protein: 552-624
Range on HMM: 22-92/144.0
ISVLSKQKKGDVICVKPKVTRKKKTHEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQqcGNVPVLVQCRY
. | |.. . ||.. .. ..|. ...|..| | ..| . .|..|. ... .. . |||| |..
lellkklgittvinlteeyepefleregiqylhlpwpDhgvpdllellleflefieeale..eggpvlVHCsa
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 577-623 | 6.2e-07 | 23.1 | In-house | 89-135 (440) | alignment | ||
Range on Protein: 577-623
Range on HMM: 89-135/440.0
HEVRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQQCGNVPVLVQCR
. ... |. .| || .||.. || ....|. ||...|| |.||.|
rtlkqyhyqgwpdkgvpkfagpvlkmiqdvnesqekagngpllvhcs
|
|||||||||
PTPc_DSPc_SM00012 | 579-623 | 7.1e-08 | 28.0 | In-house | 2-47 (105) | alignment | |||
Range on Protein: 579-623
Range on HMM: 2-47/105.0
VRHLHHVSWTDKCIPKVSRSVLDLLDEVQTSQQQCG-NVPVLVQCR
|.|.|. .|.|...|. | |.|.||..|........ . ||.|.|.
vkhyhytgwpdhgvPeesdsilellravkknknksesskpvvVhCs
|