Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
---|---|---|---|---|---|---|---|---|---|
fn3 | Fibronectin type III domain | 1-78 | 3.9e-14 | 45.7 | Pfam-A | 2-79 (85) | alignment | ||
Range on Protein: 1-78
Range on HMM: 2-79/85.0
APTSLSTTVLTSTSIRVTWSALPgtCTNGIVRKYVISYHKNGGSDETTEINAPRTS--FDISDLEKYTEYTIKVCGYTVK
||. || . ||||....||. . .| . .| . | . ||..|..|...|||. . ...|. .|||...| .. .
aPenlsvsevtstsltlsWsppk..dgggpitgYeveyrekgggeewkeftvprtttsvtltgLkpgteYefrVqavnga
|
|||||||||
fn3 | Fibronectin type III domain | 98-185 | 5.6e-12 | 38.8 | Pfam-A | 2-85 (85) | alignment | ||
Range on Protein: 98-185
Range on HMM: 2-85/85.0
SPSAVSHSEINSTTFNISWSSIPkdQRNGIITSYDLELSSGQARRrrWSIPESFTSTLTYIVLHNLESCTIYHLRVRARTGKGPGPYS
.|. .| ||..||....||| . ...| ||.|..|... . . .. . ..| | .|..|. | |..||.|..|.| ||.|
aPenlsvsevtstsltlsWsppk..dgggpitgYeveyrekggge..ewkeftvprtttsvtltgLkpgteYefrVqavngagegpeS
|
|||||||||
subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 308-598 | 9.3e-133 | 437.1 | In-house | 3-298 (298) | alignment | ||
Range on Protein: 308-598
Range on HMM: 3-298/298.0
DDLSKPISVAHFPKYVAIMQANRGIRLEAEYKNVSNEQQ----FSWDAARKAANKKKNRYGNIVTYDHSRVVLERVNGDEDSDYINASFIHGFDGTPrSY
....... |...|..|...... .....|...... .. .....||| .||||||| .|...|.||||||....||.||||||||.|...|.. ..
teieaedlkaalqklaavkkkkkltgyalefqrlnsvsseieeeekevarkpenkkkNRyadiialdssRvvLekedadeesdYiNAsflhaykgrn.af
IASQGPPPPTFEGFWRMVWEQNSQSIVMLTNLVELGKTKCHKYWPE-KTETYGGVTVTLHQTEVFADYVIRTFILFREERAVRRMVRQFNFTVWPDKGVP
||.|.| ..|.|.|||||.|.....|||||||.||.|||.|||||. ..|||| .||.|...|.|||...|.... ..... .|.|||..||.|||||||
iatqaPltetvedFWrmvteedigtiVmltnleeldktkyhkywPdegketygeitvsllskeefadlivrklkvskkkeekerevrqlhftsWpdkgvp
QYATAVLAFRRKVRAlNPRDAG--PVIVHCSAGVGRTGAYIVIDAMLEQAKINRTVDIRNYLIALRKDRPHMVQTKEQYSFIHSAVLEALTCGNTEIQ
..||.||...||||| ....|| ||||.|||||||.|..|.||..||..|....||.......|||.||..|||.|||.||..||||||...|.||.
enatsvldllrkvra.sqqqagnkpvivqCsaGvgRsGtfiaidsvlervkkeqvvDvfqvvkvlRkkrpgavqteeqYvfiyeavlealdsfndeie
|
|||||||||
0045450 | (Phosphotyrosine protein) phosphatases II | 310-590 | 1.1e-87 | 290.0 | In-house | 5-304 (307) | alignment | ||
Range on Protein: 310-590
Range on HMM: 5-304/307.0
LSKPISVAHFPKYVAIMQANRGIRLEAEYKNVSNEQQF---SWDAARKAANKKKNRYGNIVTYDHSRVVLERVNGD-EDSDYINASFI--------HGFD
||..|.. .. ..|...... .|..|.. . ... | ....|.. .||.|||| .|. |||.||.| ..|. |||||||||.. .|.|
lslfidalkllllvllllldfltgllkefekllsvtvfllgeysiallpenkdknrykdilpydhtRVklssldgsledsdYiNAsyvrvpllllldgyd
GtPRSYIASQGPPPPTFEGFWRMVWEQNSQSIVMLTNLVELGKTKCHKYWPEK--TETYGGVTVTLHQTEVFADYVIRTFILFRE-ERAVRRMVRQFNFT
.| .|| ||| | |.| ||||.|||... |||||.|||||. ||..|||.. . ||| .|||| .|. ..|..||. . . . |.|..| .|
l.krkfIatqgPlpetvedFwrmlweqgvtvivmltelvelgrekcaqywPdegeeltygnftvtllseehldgytvrtlevtdldgtgesrtvthfhyt
VWPDKGVPQYATAVLAFRRKVRALNPR--DAGPVIVHCSAGVGRTGAYIVIDAMLEQAKINRT---VDIRNYLIALRKDRPHMVQTKEQYSFIHSAVLEA
||| |||.. .|.| ..||. . . . |||.|||||||||||..|... ||.| . . | ||... . ||. ||..||. ||| |.. |.||
gwpdhgvppsfeelldfieevrkaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrflyeallel
L
|
l
|
|||||||||
subfamily_PTPRD_pd | Subfamily PTPRD | 311-772 | 6.6e-229 | 756.2 | In-house | 2-462 (564) | alignment | ||
Range on Protein: 311-772
Range on HMM: 2-462/564.0
SKPISVAHFPKYVAIMQANRGIRLEAEYKNVSNEQQFSWDAARKAANKKKNRYGNIVTYDHSRVVLERVNGDEDSDYINASFIHGFDgTPRSYIASQGPP
||||.||.....|| ..||.....| |||.....|||.|.||.| |||.|||| ||| ||||||||..|.|||.|||||||||.|.. ....|||.|||
skpipvaelkehvaklkansdlkfeeeykkieegqqftweaankpaNkaKNRyanivaYdhsRVvLskvegdegsDYINAsfidgyr.krkayIAtqgPl
PPTFEGFWRMVWEQNSQSIVMLTNLVELGKTKCHKYWPEK-TETYGGVTVTLHQTEVFADYVIRTFILFREERAVRRMVRQFNFTVWPDKGVPQYATAVL
..|.| ||||||||||..|||||.|.| ||.||||||||| |||||..||||...| .|||.||||.| .... |.||||.|| |||.|||..||..|
aetiedFWRmvweqnsstiVmltkleEkgkvkchkYWPekgtetygeltVtleeeeeladyeirtfklkkkkssesreVrqFhFtsWPdhgvpesatslL
AFRRKVRALNPRDAGPVIVHCSAGVGRTGAYIVIDAMLEQAKINRTVDIRNYLIALRKDRPHMVQTKEQYSFIHSAVLEALTCGNTEIQSENFNQTTQKL
...|||||||..||||..|||||||||||..||||||||..| ..||||..|..||||.|..||||.|||.|||.|.||||.|||||..|||..|..|||
dlirkvralnepdagPivVhCSaGVGRTGtfividamlerikeektvDiyqyvkalrkqRnamVqteeQYiFiheailealacgntevesenlkqhlqkL
ASVNRKFQMTGYALEFQRLNsfTSREIPAEEKSVGEEPQNLQKNRFCDIVALNSCRVMLRKEHADEESDYINAVFLHAHRERNAFIATQHPLLETVEDFW
|.|.....|||..||||||. |..||..||..|...|.|..|||| .|.||.||||.|....|.||||||||..|.|.||..||||||.|| .||||||
aeveedtemtgleleFqrLa..takeieleefavatkpknkkknrfsnilalescrvvlsairakeesdyinasyleayrekrafiatqaplkntvedfw
RMVTDYDIGTIVMLNNLHE-LDQEYPQYWPDHGATKYGHIGVSVLSKQEKGDVISTKLEVTRKK
|||.......||||..|.| |..|. .|..|..|||||.|...||.|.||.|.. .| .|..|.
rmvweeevkiivmltkleekleeesseyysdleatkyGeitikvlkkkeksdilfrkkkvevke
|
|||||||||
subfamily_PTPRB_pd | Subfamily PTPRB | 311-592 | 4.5e-100 | 329.5 | In-house | 4-287 (293) | alignment | ||
Range on Protein: 311-592
Range on HMM: 4-287/293.0
SKPISVAHFPKYVAIMQANRGIRLEAEYKNVSN-EQQFSWDAARKAANKKKNRYGNIVTYDHSRVVLERVNGDEDSDYINASFIHGFDgTPRSYIASQGP
||||.. .| ..|. |.|. .|. ||..... ... . .||..|.|..|||| ||..|||||| |. ......||||||..|.|. .|| .||.|||
skpiklekfeehvkkmkadsdlrfseeyeelkavgkdqavkaaelavnraknrytnilpydhsrvkLaalkdesgsDYinanyipgyn.sprefiatqGP
PPPTFEGFWRMVWEQNSQSIVMLTNLVELGKTKCHKYWPEK--TETYGGVTVTLHQTEVFADYVIRTFILFReeRAVRRMVRQFNFTVWPDKGVPQYATA
| |.. |||||||..|. |||||.||| ||.||..|||.. . .|| ..||| ..|. |.|||.. . . . .| |||..|| ||| |||. ...
lpetvddfWrmvwekkssiivmltqlvekgkvkCeeYWPadeepvlyGdikvtlvaeeeledwvirelkiek..ekeerkvrqyhftsWpdhgvPektkt
VLAFRRKVRALN--PRDAGPVIVHCSAGVGRTGAYIVIDAMLEQAKINRTVDIRNYLIALRKDRPHMVQTKEQYSFIHSAVLEALTC
.|.| |.|| ...|..|||||||||||..| .| .|.. . . .||| ...||..| ..|||..|| |||..||. |.
lldfvrtvreaiektaskrPivvhCsaGvGRtGtfialdrllqaieeedyvdifgivaelReeRnllvqtekqYifihqcvldllrk
|
|||||||||
0050432 | (Phosphotyrosine protein) phosphatases II | 311-594 | 6.4e-95 | 313.3 | In-house | 23-303 (308) | alignment | ||
Range on Protein: 311-594
Range on HMM: 23-303/308.0
SKPISVAHFPKYVaiMQANRGIRLEAEYKNVSNEQQ-FSWDAARKAANKKKNRYGNIVTYDHSRVVLervngDEDSDYINASFIHGFD-GTPRSYIASQG
|...|| .. |.. ..|. .||.|.. . . . .....|.. .||.|||| .|. ||||||.| ||.|||||||...|.. . || .|| ||
slklsvldllkll..ekaldlglleeefeellsvkplleysvallpenkdkNrykdilpydhsRVkl.....degsdYInAsyvdgyssklprkfIatqg
PPPPTFEGFWRMVWEQNSQSIVMLTNLVELGKTKCHKYWPE----KTETYGGVTVTLHQTEVFADYVIRTFILFREERAVRRMVRQFNFTVWPDKGVPQY
| | |.| |||||||||.. |||||.||| |. ||..|||. ....||..|||| .||..||..||..| . |.|..| .| ||| |||..
PlpntvedFwrmvweqnvrvIvmLtklvengrekcaqYwplelgggsleygkftvtllseevlddytvrtleltnlgdgesrtvthfhytnWpdhgvPps
ATAVLAFRRKVRALNprDAGPVIVHCSAGVGRTGAYIVIDAMLEQAKINRTVDIRNYLIALRKDRPHMVQTKEQYSFIHSAVLEALTCGN
....|.| ..|| . . ||..|||||||||||..|..| .||| . ...||. ... ||. ||.||||.||| |.. |.|| | .
peilldflelvrksl..pggpivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkklReqRpgmvqtpeqylflyralleylklkl
|
|||||||||
subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 312-626 | 3.4e-106 | 349.9 | In-house | 3-319 (319) | alignment | ||
Range on Protein: 312-626
Range on HMM: 3-319/319.0
KPISVAHFPKYVAIMQANRGIRLEAEYKNVSNEQQFSWDAARKAANKKKNRYGNIVTYDHSRVVLERVNGDEDSDYINASFIHGFDGTpRSYIASQGPPP
..| |... ... ..... || |.|.... .....| | | ||||||| ||..||..|||| ..| |.||||||||| |.. . .|| |.|
teievqeLkerlkalastgetllekefkllkeavndtfdsaskeenkkknryqnilaydrtrvvlseldgvegsdyinasfidgyqer.ekfiatqaPle
PTFEGFWRMVWEQNSQSIVMLTNLVELGKTKCHKYWPEKT-ETYGGVTVTLHQTEVFADYVIRTFILFREERAV-RRMVRQFNFTVWPDKGVPQYATAVL
|.| |||||||..| .||||.||| .| |..|||||.. |.|| ..||| . | .||.|| . | . | |.| .| .| |||..||..||..|
ntiedfWrmvWeeessivvmltklveklkvklkkywpeenfeeyGrlivtleeeeeledyiirklklnkkssevetRevkhfqyteWpdhdvPekatsll
AFRRKVRALNPR-DAGPVIVHCSAGVGRTGAYIVIDAMLEQAKINRTVDIRNYLIALRKDRPHMVQTKEQYSFIHSAVLEALTCGNTEIQSENFNQTTQK
.. ...| . ..||..|||||||||||..||.|||||. | . ..|. .. || |. |||..|||.||. |.|||...|.|||. ..... ..
dllkrirksrektqsgPivvhCsaGvGRtGtfivldamlervkeegvlDvfstvsrlRtqRnimvqrpeqYkfiyealleaveagdteievqdlrdrlkq
LASVNRKFQMTGYALEFQ
||. . . .|| . |||
laekvadtgetglerefq
|
|||||||||
0051299 | (Phosphotyrosine protein) phosphatases II | 312-590 | 1.6e-96 | 318.4 | In-house | 3-286 (288) | alignment | ||
Range on Protein: 312-590
Range on HMM: 3-286/288.0
KPISVAHFPKYVAIMQANRGIRLEAEYKNVSNEQ-QFSWDAARKAANKKKNRYGNIVTYDHSRVVLERVNGDEDSDYINASFIHGFDGTPRsYIASQGPP
..||| .. |.| ..|| .|..|.. . . . .... ||.. .|..|||| .|. ||||||.| ..|.|.|||||||.|.|.. . . .|| |||
teisveellklvlkllangltglleefeellsllpdltlsaallpenleknRysdilpydhsRVkLsvldgvegsdYinAsyidgynlkrk.fIatqgPl
PPTFEGFWRMVWEQNSQSIVMLTNLVELGKTKCHKYWP-EKTETYGGVTVTLHQTEVFADYVIRTFILFRE----ERAVRRMVRQFNFTVWPDKGVPQYA
| |.| |||||||||.. |||||.|||||..||..||| ....||| .|||| .||..||..||... . |.|..| .| ||| |||...
pntvedFWrmvweqnvrvIvmltklvelgrekcaqYwplggsltygditvtllseevlddytvrtlevtnldlldgdgesrtvthfhytnwpdhgvpdsp
TAVLAFRRKVRALNPRDAGPVIVHCSAGVGRTGAYIVIDAMLEQAKINRTVDIRNYLIALRKDRPHMVQTKEQYSFIHSAVLEAL
...|.| |.|| .. . |||.|||||||||||..|..| .||| . ...||. ... ||. ||.|||| ||| |.. |.||.|
ellldflrlvrkalasgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlreqRpgmvqtpeqyrfvyealleyl
|
|||||||||
subfamily_PTPRA_pd | Subfamily PTPRA | 312-624 | 8.3e-95 | 312.4 | In-house | 12-329 (330) | alignment | ||
Range on Protein: 312-624
Range on HMM: 12-329/330.0
KPISVAHFPKYVAIMQANRGIRLEAEYKNVSN-EQQFSWDAARKAANKKKNRYGNIVTYDHSRVVLERVNGDEDSDYINASFIHGFDGTpRSYIASQGPP
|. | .. . . | .|. .. |.... . | . ..| | ||.|||. ||. ||.|||.| ..| |.|||||||||.|. ..||.|||
fplpvekleeeirirsaddnklfreefnalPagpiqatlelaskeenkeknrvvnilPydfsrvilsvkeGveesdyinasfidGykek.dkfiaaqGPk
PPTFEGFWRMVWEQNSQSIVMLTNLVELGKTKCHKYWPEK-TETYGGVTVTLHQTEVFADYVIRTFILFR----EERAVRRMVRQFNFTVWPDKGVPQYA
| | ||||.|||.|..|||||.| | ..||..|||.. . ||| ..|......| || .| |.. . .. |.|||| || ||| ||| .
eetvedfwrmiweqksativmltelkerkeekcaqywPdeGlvtyGnirvevedetvlvdytvrkflvqqlpdatrekksrlvrqfhftswPdvGvPfep
TAVLAFRRKVRALNPRDAGPVIVHCSAGVGRTGAYIVIDAMLEQAKINRTVDIRNYLIALRKDRPHMVQTKEQYSFIHSAVLEALTCGNTEIQSENFNQT
.| . .||..||.. |||..|||||||||||..||.||.||. | .| ||. . . ||. ||.||||.||| ||. ..|| |.||.. ...
iGmlkllkkvkklnqqsagpivvhcsaGvGrtGtfivldavlervkaerkvdvfefvkrlrlqrpqmvqtdeqyefiykvlleyylygdteldvsslekh
TQKLASVNRKFQMTGYALE
||| . ... .| |
lqklynkitgtdkigleee
|
|||||||||
subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 312-609 | 1.9e-91 | 301.4 | In-house | 2-302 (305) | alignment | ||
Range on Protein: 312-609
Range on HMM: 2-302/305.0
KPISVAHFPKYVAIMQANRGIRLEAEYKNVSNEqQFSWDAARKAANKKKNRYGNIVTYDHSRVVLERVNGDEDSDYINASFIHGFDGTpRSYIASQGPPP
|.|..... .|. .... |||.||.. .| . | | .| |||.|||. .|...|..|. | . ..||||||||...|... .||..||| .
kiialddlaayikearvysdkgleaqykslyee.eesidvgkkeankaknrlkeitlldddriiltekeslddsdyinasyvdgykrk.kkyivaqgPlk
PTFEGFWRMVWEQNSQSIVMLTNLVELGKTKCHKYWPEKTET---YGGVTVTLHQTEVFADYVIRTFILFR-EERAVRRMVRQFNFTVWPDKGVPQYATA
| . |||...| ..|||||.||| || ||..||||.. .| ..|.|.... ..||..| . . .| | | |...| |||.||||.||.
ntvadfWrliveekvstivmltklveggkdkCrqYWpesktekkefgefsvelksektasdyieRklkisiededkesrtvlqyqltdWPdhGvpqfats
VLAFRRKVRALNPRDAG-PVIVHCSAGVGRTGAYIVIDAMLEQAKINRTVDIRNYLIALRKDRPHMVQTKEQYSFIHSAVLEALTCGNTEIQSENFNQTT
.| . ..|. .| | |..|||||||||||..|..| .||..| .||. ..| .||. |. ||||..|| |.| |. | .|||.|.| .|..
llslikrvqkdqkkdkgvpllVhCsagvgRtGvfiavdialerlkkEevvdvfevlkqlRskrmkmvqtldqYvflhdaldelitcgdtsiigsnlrarv
QKL
.||
nkl
|
|||||||||
subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 312-607 | 3.4e-91 | 300.5 | In-house | 4-296 (315) | alignment | ||
Range on Protein: 312-607
Range on HMM: 4-296/315.0
KPISVAHFPKYVAIMQANRGIRLEAEYKNVSNEQQFSWDAARKAANKKKNRYGNIVTYDHSRVVLERVNGDEDSDYINASFIHGFDgTPRSYIASQGPPP
.|| . .. ||| .|. .. .|... | . | |.| ||.|||| ||..||.||| | .. |..|||.||.|| |.. .| |||.||| .
qpipldqlityvaqkkastkngfkqdyesipggqlhpldvakkienkqknryiniiaydksrvqlpllendphsdyvnanfidGyn.kkrryiaaqgpnv
PTFEGFWRMVWEQNSQSIVMLTNLVELGKTKCHKYWPEKTETYGGVTVTLHQTEVFADYVIRTFILFREERaVrRMVRQFNFTVWPDKGVPQYATAVLAF
. . |||.|.|.. ||||||||| | |. ||||.| .|| .|||. . ||. .| .||. ... . | | |...| ||| |||.|..... .
asvkdfwrlvfeedigkivmltnlvegekrkaekywpdkkviyGkitvtrkseevnteytvrtlsvvfgdn.i.revvqlhytswpdmgvpkytiplmnl
RRKVRALNPRDAGPVIVHCSAGVGRTGAYIVIDAMLEQAKINRTVDIRNYLIALRKDRPHMVQTKEQYSFIHSAVLEALTCGNTEIQSENFNQTTQ
|.|. . ..|...|||||||||||..| .||.|.||.... .|. |.. .|. | .|||. ||| ||..|.||.. ||.| | . . | .
irtvkqhhtnsvgaivvhcsaGvGrtGtfitldavldqaeaenaidvynfitgvrqnrikmvqvaeqyqfiydalletfvcgdtsiaqdlylqryd
|
|||||||||
subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 312-612 | 3.3e-81 | 267.6 | In-house | 1-299 (315) | alignment | ||
Range on Protein: 312-612
Range on HMM: 1-299/315.0
KPISVAHFPKYVAimQANRGIRLEAEYKNVSNEQQFSWDAARKAANKKKNRYGNIVTYDHSRVVLERVNGDEDSDYINASFIHGFDGtPRSYIASQGPPP
.|| ||.|| .| . . . |.... . . . .||. | |||||.||. .|..||.|| .. . ||||||||.|...| ..||||||| .
qpipvaqfpafvn..knrhtalfseefhdlpdPdiyrqrvaretinfkknryknilPldsarvkleviddsPdsdyinasyiksvdd.dkayiasqgPlk
PTFEGFWRMVWEQNSQSIVMLTNLVELGKTKCHKYWPE---KTETYGGVTVTLHQTEVFADYVIRTFiLFREERAVrRMVRQFNFTVWPDKGVPQYATAV
. . |||||.... .|||.|.. | | || .|||. .. .| . |.| ..| .| |.| . |. . | | ||.|| ||||||.. ....
asvddfwrmvlqekvttivmvtkkqegdkikcrqywPdrkadsvefGsikvellsleadtdgvarkl.vtrksees.rtvtqfqftewPdkGvdkqtssl
LAFRRKVRALNPRDAGPVIVHCSAGVGRTGAYIVIDAMLEQAKINRTVDIRNYLIALRKDRPHMVQTKEQYSFIHSAVLEALTCGNTEIQSENFNQTTQK
| . ..|.| | .. ...||||||||||| | || ...|.| .|.||. |.. ||..||..|||.|.|.||. |||| | || | .| . |
lklikevkadngkkefsllvhcsaGvGrtGvvisidevvaqikrtrsvdvfnfvknlrakrpylvqteeeyafiydavledllwrntlilvihftdhlqd
LASV
| .
lhts
|
|||||||||
subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 312-602 | 5.1e-78 | 257.2 | In-house | 8-296 (297) | alignment | ||
Range on Protein: 312-602
Range on HMM: 8-296/297.0
KPISVAHFPkyvAIMQANRGIRLEAEYKNVSNEQ-QFSWDAARKAANKKKNRYGNIVTYDHSRVVLERVNGDEDSDYINASFIHGFDGtprSYIASQGPP
.|| ...|. ...| || .. | . | .. |.| | .|.|| ||. || ||| |. || | ||||.||||..|. .|..| |
rpiplsdfa...tlvqknrhtdvfseeflclpeaniqpqtvaekkvnfeksRYkniLPydssRvkLaivnddpdsDyvnasfvkgnkh...rlittqmPm
PPTFEGFWRMVWEQNSQSIVMLTNLVELGKtKCHKYWPEKT-ETYGGVTVTLHQTEVFADYVIRTFILFREERAVRRMVRQFNFTVWPDKGVPQ--YATA
. | . ||.||.... . ||||... | | || .||..|. |.| |.|.|. .. .. |.. . ... .||.|.|..|. |||| |.. |..
katvadfWamvldeqvstivmlnddnerdk.kcaryWsdkgvttfGdvsvvllsvsereGfikrelevtkgkakarrvvkqyqfveWPdkaverkdsass
VLAFRRKVRALNPRDAG-PVIVHCSAGVGRTGAYIVIDAMLEQAKINRTVDIRNYLIALRKDRPHMVQTKEQYSFIHSAVLEALTCGNTEIQSENF
.| . || | |..|||.||||||| .. || .. .|| . .||| ... ||..||..|||||||.|.. |||||| . .|.||.. |
llklisevrkdfsqnaegPllvhclaGvGrtgvlltidsvvaeakrekevdifglvkklrqerpylvqtkeqykfvyvavleallsedtriqasyf
|
|||||||||
subfamily_Urchin-PTP-4_pd | Subfamily Urchin-PTP-4 | 312-613 | 1e-67 | 223.3 | In-house | 2-259 (392) | alignment | ||
Range on Protein: 312-613
Range on HMM: 2-259/392.0
KPISVAHFPKYVAimQANRGIRLEAEYKNVSNEQQFSWDAARKAANKKKNRYGNIVTYDHSRVVLERVNGDEDSDYINASFIHGFDGTpRSYIASQGPPP
.|| ||.|| .| . . . |.... . . . .|.| |.|||||.||. || .||.|| .. ||||.|||.|..|| ..||||||| .
qpipvaqfpafve..knrhsalffeefhdlpgpdiypqtvaqkeinlkknryknilpydsarvkleviddipdsdylnasyipsfdne.kayiasqgpna
PTFEGFWRMVWEQNSQSIVMLTNLVELGktkchkywpektetyggvtvtlhqtevfadyvirtfilfreERAVRRMVRQFNFTVWPDKGVPQYATAVLAF
... |||||...| .|.|.|.| | | | || || ||||.||......| |
aslddfwrmvfqenvttiamvtklkegd.........................................kgddartvaqfhftewPdkdvpkhtssllkf
RRKVRALNPRDAGPVIVHCSAGVGRTGAYIVIDAMLEQAKINRTVDIRNYLIALRKDRPHMVQTKEQYSFIHSAVLEALTCGNTEIQSENFNQTTQKLAS
..|.| . . |.|.|||||||||| | ||... .|| | ||. |.. .|. ||.||||||||.||. |||| | || | | . |.| .
ikevkadfGqythpliihcsagvgrtgvvisidsvvahakktrmvdvfnfvtnirrkrpymvqtkeqyafiygavledllwrntlipvvhftdhlqdlst
VN
ss
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 312-397 | 1.2e-15 | 51.8 | In-house | 4-87 (440) | alignment | ||
Range on Protein: 312-397
Range on HMM: 4-87/440.0
KPISVAHFPKYVAIMQanRGIRLEAEYKNVSNEQQFSWDAARKAANKKKNRYGNIVTYDHSRVVLERVNGDEDSDYINASFIHGFD
.|| || | || . | | |. . . . | | || |||| ||..||||||.|| |.| ||||||||.| | .
rpiivadfadyvqnnr..rsrafedewsllpsglsqpsdiaslpnnkvknryrnilaydhsrvmleevkgvpdsdyinasyingie
|
|||||||||
subfamily_Sponge-PTP3_pd | Subfamily Sponge-PTP3 | 312-408 | 5.1e-15 | 49.4 | In-house | 3-95 (95) | alignment | ||
Range on Protein: 312-408
Range on HMM: 3-95/95.0
KPISVAHFPKYVAIMQANRGIRLEAEYKNVSNEQQFSWDAARKAANKKKNRYGNIVTYDHSRVVLErvnGDEDSDYINASFIHGFDGtPRSYIASQG
||| |. | .| |..| .. |.| .| .. . || |||. ||. || .|||| ||||||| |. |. |||.||
kpihvsvfhshvlemhsnsdqefdnefksismtsgapytvgsseanipknrflnifpydatrvvlt...tkrdsdyinacfvdgyar.kncyiaaqg
|
|||||||||
0043336 | (Phosphotyrosine protein) phosphatases II | 313-588 | 5.3e-91 | 300.2 | In-house | 1-275 (278) | alignment | ||
Range on Protein: 313-588
Range on HMM: 1-275/278.0
PISVAHFPKYVAIMQANRGIRLEAEYKNVSNEQQFSWDAARKAANKKKNRYGNIVTYDHSRVVLERVNGDEDSDYINASFIHGFDGTPRsYIASQGPPPP
|||| ...|... . .| .|..|.... . . .... |.. .||.|||| .|. ||||||.|. ..||.||||||||.. |.. ... .||.||| |
pisvkdllkallelllnlktllllefeellsfkldtysiallpenkdknrykdilpydhsrvklsllggdldsdYinAsyvdgynvprk.fiatqgPlpe
TFEGFWRMVWEQNSQSIVMLTNLVELGKTKCHKYWPEKTETYGGVTVTLHQTEVFADYVIRTFILFREERAVRRMVRQFNFTVWPDKGVPQYATAVLAFR
|.| |||||||.....|||||.|||||..||..|||....|||..|||| .|...||..||. . . |.|... .. ||| ||| . .| |
tvedFwrmvwelgvttivmLtelvelgrvkcaqYwpggsltygdftvtllkeehlddytvrtlevtnlgdgesrtvthyhylgwpdhgvpeslsllldfl
RKVRALNPRDAGPVIVHCSAGVGRTGAYIVIDAMLEQAKINRTVDIRNYLIALRKDRPHMVQTKEQYSFIHSAVLE
..|| .. . |||.|||||||||||..|... .|||.. ...||. . . ||. ||..||| .|| |.. |.||
kavrealedsngpvlVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqRpgavqtpsqyrflyealle
|
|||||||||
0039614 | (Phosphotyrosine protein) phosphatases II | 313-594 | 7e-90 | 296.8 | In-house | 13-293 (297) | alignment | ||
Range on Protein: 313-594
Range on HMM: 13-293/297.0
PISVAHFPKYVAIMQANRGIRLEAEYKNVSNEQQfSWDAARKAANKKKNRYGNIVTYDHSRVVLERVNG-DEDSDYINASFIHGFDGTPRSYIASQGPPP
||.. ... .. ...|| .|..|.... . . .. |.. .||.|||| .|. ||||||.| ..| |.||||||||.. |.| ..| .||.||| |
piplsvldlllllekansktllllefeellslkp.dysiallpenkdknrykdilpydhsrvklkpedgvdldsdYinAsyvdgydlltrkfIatqgPlp
PTFEGFWRMVWEQNSQSIVMLTNLVELGKtKCHKYWPEKTETYGGVTVTLHQTEVFADYVIRTFILFReeRAVRRMVRQFNFTVWPDKGVPQYATAVLAF
|.| ||||||||....|||||.|||||. ||..||||...|||..|||| ..|. ..|..||. . . |.|..| .| ||| |||.... .| |
etvedFwrmvweqgvtvivmLtklvelgr.kcaqywpeeggtygdftvtllkvehldgytvrtlevtn..ngesrtvthfqytgwpdhgvppslelllef
RRKVRALNPR--DAGPVIVHCSAGVGRTGAYIVIDAMLEQAKINRTVDIRNYLIALRKDRPHMVQTKEQYSFIHSAVLEALTCGN
..|| . . . |||.|||||||||||..|... |||| . ...||. . . ||. ||..||| .|| |.. |.|| | ...
lelvrealaelpkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavqtpsqyrflydallellkrkl
|
|||||||||
subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 313-634 | 2.7e-82 | 271.5 | In-house | 1-320 (515) | alignment | ||
Range on Protein: 313-634
Range on HMM: 1-320/515.0
PISVAHFPKYVAimQANRGIRLEAEYKNVSNEQQFSWDAARKAANKKKNRYGNIVTYDHSRVVLERVNGDEDSDYINASFIHGFDGtPRSYIASQGPPPP
|. .| || .|. .... . |.... . . |.. | |||||.||. || .|| || .| . .|||.|||.|..|| ..||||||| .
plplaqfPafvn..knrhttlfseefhdlpgpniypqtvaqeeinfkknryknilPydsvrvklevindnPhsdyfnasyipsfdn.dkayiasqgPnka
TFEGFWRMVWEQNSQSIVMLTNLVELGKTKCHKYWPE---KTETYGGVTVTLHQTEVFADYVIRTFILFREERavRRMVRQFNFTVWPDKGVPQYATAVL
. . |||.|...| |.|.|.| | | || ||||. .. .| . | | .| .. ..|.. . ... | | ||.|| |||||||. ....|
svddfWrlvlqenvttiamvtklkegdkikcgkyWPdkpgdsvkfGsikvelvsleactggikrkltvlkgdd..srtvtqfhfteWPdkGvpkhtssll
AFRRKVRALNPRDAGPVIVHCSAGVGRTGAYIVIDAMLEQAKINRTVDIRNYLIALRKDRPHMVQTKEQYSFIHSAVLEALTCGNTEIQSENFNQTTQKL
. ..|.| . . . |.|.|||||||||| .| || .. .|| |.||. |.. .|..||..|||.|||.||. |||| | || | | . | |
klikevkadhgqythpliihcsaGvGrtGvvisidsvvahakttrmvdvfnfvtnirqkrpylvqtqeqyafiygavledllwrntlipvihftdhlqdl
ASVNRKFQMTGYALEFQRLNSFTSR
| . . ||| |.|..
hssgdgrgrskmtkefqtlkslcpd
|
|||||||||
subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 314-628 | 6.5e-111 | 365.4 | In-house | 2-318 (318) | alignment | ||
Range on Protein: 314-628
Range on HMM: 2-318/318.0
ISVAHFPKYVAIMQANRGIRLEAEYKNV-SNEQQFSWDAARKAANKKKNRYGNIVTYDHSRVVLERVNGDEDSDYINASFIHGFDgTPRSYIASQGPPPP
||| .. . |. .... . |..||... .|..... . . .||.|||| ||..|||.|| |. ..|.|.||||||..| |. ..|||.|.| |
isvedleshvrrlresGelllseeyerlsrseetvtslkslepvnkaknryanilaydhtrvkLqmlegeegsDyinanyidGyr.rkkayiaaqaPlpe
TFEGFWRMVWEQNSQSIVMLTNLVELGKTKCHKYWPEK-TETYGGVTVTLHQTEVFADYVIRTFILFREERAVRRMVRQFNFTVWPDKGVPQYATAVLAF
|.| ||||||||||. |||||...| ||.|.|.|||.| ...|| ..|.|... ..|||.|.| . |.| |.|||...| |||.|||. .. .|..
tieDfWrmvWeqnsavivmltqeeergkakvhryWPskgsrsygklvvelkeevelsdyvlrefkvtrteeeesrqvrqyhytsWpdegvpesgaslldl
RRKVRALN-PRDAGPVIVHCSAGVGRTGAYIVIDAMLEQAKINRTVDIRNYLIALRKDRPHMVQTKEQYSFIHSAVLEALTCGNTEIQSENFNQTTQKLA
|.|.. . . .|||..||||||||||| .|..|..||..| . .||. .. ||. |. ||||..|| ||. ..||||..|.||........ ..|
vrqvskaqqksgagpivvhCsaGvGrtGvfiavdillerikaealvDvfqtvkqlreqrnlmvqtedqyefiydvllealasgdtevdasdlrsrirelr
SVNRKFQMTGYALEFQRL
.. . .| .|||||
eqdpesgttemdaefqrl
|
|||||||||
subfamily_PTPRG_pd | Subfamily PTPRG | 314-606 | 1.9e-98 | 325.1 | In-house | 1-303 (563) | alignment | ||
Range on Protein: 314-606
Range on HMM: 1-303/563.0
ISVAHFPKYVAIMQANRGIRLEAEYK---NVSNEQQFSWDAARKAANKKKNRYGNIVTYDHSRVVLERVNGDEDS-DYINASFIHGFDgTPRSYIASQGP
. | .| |.|| . |. |....|.. . ...... ....| ||.|||| |||.||.||| |. . | ... |||||..|.|. . .||.|||
vpvkefakhvaslhadgdigfseefealqsetiskdldaehsqkpenkrKnRylnivaydrsRvklsplpgkkkklDYinAnyidGyq.kskafiatqgp
PPPTFEGFWRMVWEQNSQSIVMLTNLVELGKTKCHKYWPE-KTETYGGVTVTLHQTEVFADYVIRTFILFR------EERAVRRMVRQFNFTVWPDKGVP
. ||. ||||.||||.. |||.||||| |. ||. |||. ..|||| ..||| ..||.| | .||... ... ..|||...| |||.|||
lkdtfddFWrmiWeqnvaiivmitnlvergrrkcdvYWPkdesetygalqvtlieeevlalytvrtlviknlklkkkkqcdteklvrqyhytkWPdhgvP
QYATAVLAFRRKVRALNPRDAGPVIVHCSAGVGRTGAYIVIDAMLEQAKINRTVDIRNYLIALRKDRPHMVQTKEQYSFIHSAVLEALTCGNTEIQSENF
.... || | .| | |...|||..||||||||||| |||.|..|.| . . .|.. . | .| |...|||.||| |.| |.|||.. ..||...|.
ehslpvLifvkkssaankaeaGPivvHcsaGvgrtGtyivldtllkqiqqenavnvfgflkhiraqRnflvqteEqYiflhdalleaiasketellaeqv
NQTT
..
eelk
|
|||||||||
subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 314-594 | 3.2e-69 | 228.0 | In-house | 2-287 (290) | alignment | ||
Range on Protein: 314-594
Range on HMM: 2-287/290.0
ISVAHFPKYVAIMQANRGIRLEAEYKNV-SNEQQFSWDAARKAANKKKNRYGNIVTYDHSRVVLERVNGDED--SDYINASFIHGFDGTpRSYIASQGPP
| | .| ..|| .|. . ....| . | |.... . ||..||. ||| || |..| ...|..| .||||..|.|. ..||| |||
ipvdkfgefvanghakgnegfrnqfkmldsgesehtvtvgltssnkllnRfanivvyddnritLrpisghkDCtneyinAcyikgykek.kqyiatqgpv
PPTFEGFWRMVWEQNSQSIVMLTNLVELGKTKCHKYWPEK-TETYGGVTVTLHQTEVFADYVIRTFILFREER-AVRRMVRQFNFTVWPDKG-VPQYATA
. | ||...|.... |||||| .| ||.||..|||.. |..|| ....|.. |.. .|..|.. . .. . ...| |...| |...| |....|
sntlvdFWkliwqekvtiivmltniieegkvkCqqYWpdsdtkaygefsikllneetlneyierklevknknsagakqsvtqyqitnwdstgkvtnpqti
VLAFRRKVRALNPRDAGPVIVHCSAGVGRTGAYIVIDAMLEQAKINRTVDIRNYLIALRKDRPHMVQTKEQYSFIHSAVLEALTCGN
.|.... .. | ....||||..|||.. ..... ....|.. .|. . | .| .| .|||..|| .|.. ||..|.. .
llvieemyktqrkrgntsivvHCSdtvgrsavfcaaattinkcktegvidvfqvlksqRiqkpgsvqtvqqyqgifqivltyldsfe
|
|||||||||
subfamily_PTPRK_pd | Subfamily PTPRK | 315-610 | 2.6e-98 | 323.7 | In-house | 5-297 (314) | alignment | ||
Range on Protein: 315-610
Range on HMM: 5-297/314.0
SVAHFPKYVAIMQANRGIRLEAEYKNVSNEqqfsWDAARKAANKKKNRYGNIVTYDHSRVVLERVNGDEDSDYINASFIHGFDgTPRSYIASQGPPPPTF
|| . .|..... | . ||... . ||||.| |..|||.|.|..||.|||.| ..|| .||||||..| .. |. .|. ||| . |
rvadllqsiallkraegygfkeeyeslfeg....wdaakkdenreknrsgdilaydrsrvflitidgdpssdyinaalidsyk.rpaafivtqgPlqetv
EGFWRMVWEQNSQSIVMLTNLVELGKTKCHKYWPEKTETYGGVTVTLHQTEVFADYVIRTFILFREERA--VRRMVRQFNFTVWPDKGVPQYATAVLAFR
. |||.|...|. ||||||.||| |. || |||||.||.|| . |.| .||. |..|.|.| . . .|. .|.||||.|. ||| .||..||..|..
kdfWrlvydencasivmltelvevgrvkClkyWPedtevygdikvelvetellaelvvrifrveklargqeeirevrqfqflgWpdhdvPvsatgllklv
RKVRALNPRDAGPVIVHCSAGVGRTGAYIVIDAMLEQAKINRTVDIRNYLIALRKDRPHMVQTKEQYSFIHSAVLEALTCGNTEIQSENFNQTTQKLA
|.| . .. .||...|||||| ||||..|.|| .|. .. ...||. | .||. .. ||.|.||| ||. ..||| ||.| | .|. . .
rrvkksqeeeaGrivvhCsaGaGrtGtfiaidivldmieregvvdvfnavktlrsrkvnmveteeqykfiydvileaclcgetaipvsefkalylesi
|
|||||||||
0040438 | (Phosphotyrosine protein) phosphatases II | 316-601 | 7.5e-95 | 313.1 | In-house | 2-287 (317) | alignment | ||
Range on Protein: 316-601
Range on HMM: 2-287/317.0
VAHFPKYVAIMQANRGIRLEAEYKNVSNEQQFSWDAARKAANKKKNRYGNIVTYDHSRVVLERVNGDEDSDYINASFIHGFDGTPRsYIASQGPPPPTFE
| ...... . .. .|. |.... . . ... |.. .||.|||| .|. ||||||.| ..||.||||||||...|.. ... .|| ||| | |.|
vldlllalldllksdftalleefedllslkldtysvaelpenkdknrypdilpydhsRVkLsplggdldsdYInAsyvdgpnlkrk.fIatqgPlpntve
GFWRMVWEQNSQSIVMLTNLVELGKTKCHKYWP-EKTETYGGVTVTLHQTEVFADYVIRTFILFREERAVRRMVRQFNFTVWPDKGVPQYATAVLAFRRK
||||||||....|||||.|.|||. ||..||| ..| |||..|||| ..|. |....||. . . |.|..| .| ||| |||.. . .|.| ..
dFwrmvweqgvtvivmLteleelgrekcaqYwplgetltygdftvtllseeelagitlrtlevedlgdsesrtvthfhytgWpdhgvppspdllldflea
VRALNPRDAGPVIVHCSAGVGRTGAYIVIDAMLEQAKINRTVDIRNYLIALRKDRPHMVQTKEQYSFIHSAVLEALTCGNTEIQSEN
||. .... |||.|||||||||||..|... |||| . ...||. . . ||. ||..||| ||| |.. |.|| |....| . .
vrealedpggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrflydalleylkrkltlepase
|
|||||||||
subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 316-597 | 1.2e-67 | 222.9 | In-house | 4-285 (287) | alignment | ||
Range on Protein: 316-597
Range on HMM: 4-285/287.0
VAHFPKYVAIMQANRGIRLEAEYKNVSN--EQQFSWDAARKAANKKKNRYGNIVTYDHSRVVLErvngDEDSDYINASFIHGFDGTpRSYIASQGPPPPT
| .| ..|| .|. . .. . . ... . . ||.|||. .|. .| ||.|. .|. |||||.|| |. . .|....| |
vekfgefvakghakgnegfknqftvleqvtqredevthniasqnkdknRltqilvpdnyrvllk....gehpdyinavfidgykek.kafiiaesPmfnt
FEGFWRMVWEQNSQSIVMLTNLVELGKTKCHKYWPEKT-ETYGGVTVTLHQTEVFADYVIRTFILFREE-RAVRRMVRQFNFTVWPDKG-VPQYATAVLA
||......| . ||||... | . .|..||||.. ..| ...| . || |.|..|.. . ... . ...|.|...| |...| |....| .|
arnfWkliddrnvtaivmlcqekendeevcyqyWpeeksvvlGeyniellneevnagyierklevknknkagdkqqvkqyqitnWdstgkvtepqtillv
FRRKVRALNPRDAGPVIVHCSAGVGRTGAYIVIDAMLEQAKINRTVDIRNYLIALRKDRPHMVQTKEQYSFIHSAVLEALTCGNTEI
. ..... | ....||||..|||.. .. .. ....| . ..|. . | | .|..||| ||| || .||| |....|
ieemyktqrkrgntsivvhCsdtvGrsamfcaaattinkckteGviDvfqvlksqriqkpgsvqtveqykfindivleyldsfetys
|
|||||||||
subfamily_CG7180_pd | Subfamily CG7180 | 320-594 | 5.4e-66 | 217.2 | In-house | 6-294 (296) | alignment | ||
Range on Protein: 320-594
Range on HMM: 6-294/296.0
PKYVAIMQANRgIRLEAEYKNVSNEQQFSWDAARKAANKKKNRYGNIVTYDHSRVVLERVNGDEDSDYINASFIHGFDgTPRSYIASQGPPPPTFEGFWR
|.| .. | . . |.| ... .. .. .. |..|||. ..| ||. |||||...|.|.||||||... .| .. || ..| | . |||
lklvdkrrkfr.veyklelkltprleigdCagglrkenreknrdvkvvPyDynRvvLekldGeeksdYinavyvdsfl.kkkeyivteapkketvdefWr
MVWEQNSQSIVMLTNLVELGKtKCHKYWPEK-TETYGGVTVTLHQTEVFADYVIRTFILFRE----------ERAVRRMVRQFNFTVWPD-KGVPQYATA
.|........|.||. . | ....|||.| | || . | . ... .|. .|||| | .. . | |.|..|..|.|. . || ..|
lvydeeisavvvLtktfdfak.mypsywpnkskeqygeifveiveekqyanlkirtfkltkkivalteqekqvkaetRivklfqlteWeledkvPlstna
VLAFRRKVRALNPRD-----AGPVIVHCSAGVGRTGAYIVIDAMLEQAKINRTVDIRNYLIALRKDRPHMVQTKEQYSFIHSAVLEALTCGN
.. .||.|| . . |||.|..| |..|.|.|. ||| ||..... ||. ... ||..||..|...|.| .| .|||. |.
lielrrrvrlwrekvdedpeegPvvvvssdGasRsGvylaidanlelvekeeevdvFeavktlrrsRpqLvenveeYkyiYdvlleavlcnk
|
|||||||||
subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 321-589 | 9.3e-89 | 292.3 | In-house | 10-278 (288) | alignment | ||
Range on Protein: 321-589
Range on HMM: 10-278/288.0
KYVAIMQANRGIRLEAEYKNVSN-EQQFSWDAARKAANKKKNRYGNIVTYDHSRVVLERVNGDEDSDYINASFIHGfDGTPRSYIASQGPPPPTFEGFWR
..||...|. .. ||..... |.. | .|.|.| |.||||| ||..||. || |. .. ...||||||.|.| .. . |||.||| . | . ||.
akvakksarnrtgfseeynsLaalektksvtagrlavnakknRyrnilpyDekrvklkkleeeagaDYinasyidg.ekkkkkyiatqgPladtvndfWe
MVWEQNSQSIVMLTNLVELGKTKCHKYWPEKTE--TYGGVTVTLHQTEVFADYVIRTFILFreERAVRRMVRQFNFTVWPDKGVPQYATAVLAFRRKVRA
.|.|.... |||||.||| |||||..|||.. . || ||||| ... |.| |...| . .. . |.....|||.|||. .. .|...|.|
lvyenktstivmltelveggktkCeeYWPdadkpknyGsvtvtlveskeledfvlrkllle..kkkteleitqyqylaWpdhgvPeskapllellrqvkv
LNPRDAGPVIVHCSAGVGRTGAYIVIDAMLEQAKINRTVDIRNYLIALRKDRPHMVQTKEQYSFIHSAVLEA
|. |.||.|||||||||||| .|..||.... . . ..|. . . ||| |. .|||..|| ||....|.
anqadtgpiivhCsaGvGrtgtFialdalidaveeedyiDvagtvaklRkqRallvqtlkqYefiyevllsl
|
|||||||||
subfamily_PTPN9_pd | Subfamily PTPN9 | 321-588 | 8.7e-73 | 239.9 | In-house | 8-288 (297) | alignment | ||
Range on Protein: 321-588
Range on HMM: 8-288/297.0
KYVAIMQaNRGIRleAEYKNVSNEQQ-FSWDAARKAANKKKNRYGNIVTYDHSRVVLERVNGDEDSDYINASFIHGFDgTPRSYIASQGPPPPTFEGFWR
.|| .. .||.. ||... ||. .|... || .|||| ... ||..||||..|..|| ||||||.|. |. ....|| ||| . |.. |||
ayvkekg.krGls..keyaeirnepveGtflasklranleknrytdvlcydetrvvlakvdedeasdyinanfvdGyk.qkkafiatqGplkktvsdfWr
MVWEQNSQSIVMLTNLVELGKTKCHKYWP---EKTETYGGVTVTLHQTEVFADYVIRTFILFREERAVRRMVRQFNFTVWPDKGVPQYATAVLAFRRKVR
|||||. ||| | .|| |. || .||| |... .| ..|. ..|. ||..|.. . . . | | | |. ||| |||. |...| ...|||
mvWeqevlvivmttrvvergrlkcgqyWpleeessaefgdlsvsnveveeeedykvrvleiknvkteesrkvthfqflsWPdyGvPssaaslldvlekvr
A--------LNPRDA-----GPVIVHCSAGVGRTGAYIVIDAMLEQAKINRTVDIRNYLIALRKDRPHMVQTKEQYSFIHSAVLE
| .... |..||||||.||||..| .| |.. . |||... . ||. | ...|| ||| | . ||||
ekqalavkelgdewkghpsgPPivvhcsaGiGrtGtfitldiclsrleevgtvdvvetvkllrtqrafsiqtpeqyefcylavle
|
|||||||||
subfamily_Ptp69D_pd | Subfamily Ptp69D | 324-609 | 3.6e-82 | 270.9 | In-house | 14-305 (307) | alignment | ||
Range on Protein: 324-609
Range on HMM: 14-305/307.0
AIMQANRGIRLEAEYKNVS-NEQQFSWDAARKAANKKKNRYGNIVTYDHSRVVLERVNGDEDSDYINASFIHGFDGTpRSYIASQGPPPPTFEGFWRMVW
. . |. ||... .| . | .. | |. |||| .|...|. ||.|...||.|||||||||||.|.. . ...||.|.| | . ||||..
ksrkrdtdfglakeyekLeareidkstkvsekkenalknRyedikafDktRvkLkkingkedsdYinasfikgykek.kkfiaaqdPveatigDfWRmia
EQNSQSIVMLTNLVELGKTKCHKYWP-EKTETYGGVTVTLHQTEVFADYVIRTFILFREERAV-----RRMVRQFNFTVWPDKGVPQYATAVLAFRRKVR
||... ||||.|| | . ||.|||| |.. || . |.| ..| ||.||.. . . . . .| | |...| |.| ||. |...| . ..||
eqevtlivmlsnlteknrkkcakYWpiedevqygdilvklvseekhsdyiiReldvskkkeesgevedsrkvvqyhytgWkDskvPevargllklieqvr
ALNPRDAGPVIVHCSAGVGRTGAYIVIDAMLEQAKINRTVDIRNYLIALRKDRPHMVQTKEQYSFIHSAVLEALTCGNTEIQSENFNQTTQKL
|. . .|..|||||||||.| .. .| .|.| | . .||| . ||..|. .|| |||.|.. |.|. . |.|... ...... ..|
elyklnrsPivvhCsaGvgrsgifvaldsllqqlkaedkvdifetvkdLrsqRnllvqsleqYvflyralldyssygdtdedvddledaierl
|
|||||||||
subfamily_Sponge-PTP9_pd | Subfamily Sponge-PTP9 | 324-596 | 2.9e-58 | 191.9 | In-house | 10-299 (301) | alignment | ||
Range on Protein: 324-596
Range on HMM: 10-299/301.0
AIMQANRgirLEAEYKNVSNEQQFSWDAARKAANKKKNRYGNIVTYDHSRVVLERVNG--DEDSDYINASFIHGFDGTpRSYIASQGPPPPTFEGFWRMV
|....|. .|..||....... | . . .||. ||. ||..||. |..|. . .|||||.|.|. . . .||.||| | |||..
aakhsnk...feeqykelkegedksctvglseenkalnrfknitvyddnriilkpkpnldlcqreyinasyidgysek.kkfiaaqgpmkktlvdfWrli
WEQNSQSIVMLTNLVELGKTKCHKYWPE---KTETYGGVTVTLHQTEVFADYVIRTFILFREE--------------R-AVRRMVRQFNFTVWPDKGV-P
|.. .||||.||| | |.||..|||. ..|..| .||||... |. |.||| . . .. . . | |.. | ||. || .
wqekpvsivmvtnlkegtkskceqywpnseaeseefgpftvtlvneqvyPdfvirqlnvkiqdgsnngyierkfkvksdksswdvlqlqvtdWpqdGvvr
QYATAVLAFRRKVRALNPRDAGPVIVHCSAGVGRTGAYIVIDAMLEQAKINRTVDIRNYLIALRKDRPHMVQTKEQYSFIHSAVLEALTCGNTE
...| . . . . . . |||.||||..|.|.| |. .. |||.| . ||. . |.|. .| .|.| |||..|. .. . |.. .|.
eprtvLqviddvihrqqkigggpvvVHCSdtVsrsGvYcsvsiglEQckaegVVdvfqvtkavrrskpgaVtTLeqytsiydvidmylqlnsty
|
|||||||||
subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 326-591 | 3.7e-87 | 287.0 | In-house | 9-277 (281) | alignment | ||
Range on Protein: 326-591
Range on HMM: 9-277/281.0
MQANRGIRLEAEYKNVSN-EQQFSWDAARKAANKKKNRYGNIVTYDHSRVVLERVNGDEDSDYINASFIHGFDGtPRSYIASQGPPPPTFEGFWRMVWEQ
...| . ||..... ... . |... .|..|||| ||| ||..||.... . ....|||||.|. |..| .. |||.||| | ... ||.|||||
lsqndnaGfieeyeklaaigvdntataskadenvlknrYsnivaYDatrvkvtpneenkntDYinanfvpgykg.ekeyiatqgPvPaslvafWqmvweq
NSQSIVMLTNLVELGKTKCHKYWPEKT--ETYGGVTVTLHQTEVFADYVIRTFILfREERAVRRMVRQFNFTVWPDKGVPQYATAVLAFRRKV-RALNPR
. . |||.|. .| || |||.|||... .|| |||. ...| | |. |.| | ..| . | |.|...| |||.|||. ....| ||..| .. ...
kvsaivmvtreieagklkChrYWPddnselkygdvtvkstaeeekatyierkfkl.eresgetreveqlaytaWPdhGvPattkellefrkevlkltekk
DAGPVIVHCSAGVGRTGAYIVIDAMLEQAKI-NRTVDIRNYLIALRKDRPHMVQTKEQYSFIHSAVLEALT
|...||||||||||.|| .| ...... ....|... . |||.| |||| ||.|.. |||.||
tkaplvihCsaGvGrtGtyialDrlvkaveaeleeldvkavvaelrkernlmvqtvvqyefvykavldald
|
|||||||||
subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 327-613 | 5.2e-73 | 241.0 | In-house | 18-311 (325) | alignment | ||
Range on Protein: 327-613
Range on HMM: 18-311/325.0
QANRGIRLEAEYKNVSNEQQFSWDAARKAANKKKNRYGNIVTYDHSRVVLERVNGDEDSDYINASFIHGFDGTpRSYIASQGPPPPTFEGFWRMV--WEq
.|. . |.. . ... . .| | .||.|||. |.|..|.|||||| . | .|||||||... . . ..|.| | . | . .||.| |.
kaqdqdgfahefgllpsddgiakkvamkpenkaknrfknvvaldksrvvletkkddpssdyinasylrddkkk.dvflaaqaPltatindlWrlvldWr.
nsQSIVMLTNLVELGKTKCHKYWPEK---TETYGGVTVTLHQTEVFADYVIRTFILFREERAVRRMVRQFNFTVWPDKGVPQYATAVLAFRRKVRAL---
|.|...| ..||| .| .|||.. . |.||. | | | ..||| | . . . .. | |.||.. |.| ||... ...... . | |.
..csvvvvlneldlgkdrcavywpkemgksktfGglevklrtieeisdyvhrvldvkqvkkGetrsvkqfqlqswddmGvqkrpatlisilqlvkavser
---NPRDAGPVIVHCSAGVGRTGAYIVIDAMLEQAKINRTVDIRNYLIALRKDRPHMVQTKEQYSFIHSAVLEALTCGNTEIQSENFNQTTQKLASVN
| . ..|..|||||||||||..| . ..|.. . ||| ... |||||| ||.| .||..|. |. ||. .|||.. .|. | |
vtantkastpilvhcsaGvGrtGvfislysalakvieesrvdifgfvkklrkdrpsmvetvdqyiliyealveaymsgntdvpvssfeaklsslqern
|
|||||||||
subfamily_egg_pd | Subfamily egg | 327-587 | 4.8e-23 | 76.3 | In-house | 15-267 (307) | alignment | ||
Range on Protein: 327-587
Range on HMM: 15-267/307.0
QANRgiRLEAeYKNVSNEQQFSwdAARKAANKKKNRYGNIVTYDHSRVVLERVNGDEDSDYINASFIHGFDgTPRSYIASQGPPPPTFEGFWRMVWEQNS
. .| ||| .....|. . | .. |..| | . | ||| || .| |.| | ..| .| .| | | . |||||....
eler..rlev.leesvdeislt..taasdnnlekarskrvhckdssrvklelrrGqylddfihanrvkGkp.llnefilaqaplkntvddfwrmvfqeev
QSIVMLTNLVELgkTKCHKYWPEKTE-T----YGGVTVTLHQTEVFADYVIRTfilfREERAVRRMVRQFNFTVWpdKGVPQYATAVLAFRRKVRALNpR
| ||||| .| .|. ||| . . |.. .. . . || . | . . | . | .| .... | | .| | .
qyivmltsrkes..erceyywpkaesdslvtvpGslrienlkvdskadplfrv....tklklvGgddeerflehw..qgdvnnssdvysplrvlrklr.n
DAGPVIVHCSAGVGRTGAYIVIDAMLEQA---KINRtVDIRNYLIALRKDRPHMVQTKEQYSFIHSAVL
. ||.|.. || .... . |. | . | . ... ||. |. |.. .| |.. ||
lskpvvvqdilGvskaatlvaieiallsllrGpitk.slvlravvflrlrrrlsvesvllylfvyrlvl
|
|||||||||
0047943 | (Phosphotyrosine protein) phosphatases II | 329-590 | 3.8e-87 | 287.5 | In-house | 9-272 (273) | alignment | ||
Range on Protein: 329-590
Range on HMM: 9-272/273.0
NRGIRLEAEYKNVSNEQ-QFSWDAARKAANKKKNRYGNIVTYDHSRVVLervnGDEDSDYINASFIHGFDGTPRsYIASQGPPPPTFEGFWRMVWEQNSQ
. .|..|.. . . . .... .|.. .||.|||| .|. ||||||.| ||..|||||||.. |.. ... .|| ||| | |.| |||||||||..
lgltllleefelllslkplltysvallpenkdknrykdilpydhsrvkl....gdggsdyinAsyvdgynlkrk.fiatqgPlpntvedfwrmvweqnvr
SIVMLTNLVELGKTKCHKYWPEK----TETYGGVTVTLHQTEVFADYVIRTFILFREERAVRRMVRQFNFTVWPDKGVPQYATAVLAFRRKVRALNPR--
|||||.|||||. ||..|||.. ..||| .|||| .|...||..||..| . . |.|..| .| ||| |||.. . .| | ..|| .
viVmLtelvelgrekcaqYwpleggelsltygkftvtllseetkddytvrtleltnlgtgesrtvthfhytgwpdhgvppslesllefielvrkalealp
DAGPVIVHCSAGVGRTGAYIVIDAMLEQAKINRTVDIRNYLIALRKDRPHMVQTKEQYSFIHSAVLEAL
. |||.|||||||||||..|..| .|.| . ...||. ... ||. ||.|||| ||| |.. |.|| |
sngpvvVHCsaGvgRtgtfialdllldqlekeggvdvleavkllrsqRpgmvqtpeqyrflyealleyl
|
|||||||||
0049772 | (Phosphotyrosine protein) phosphatases II | 331-592 | 8.5e-42 | 139.3 | In-house | 20-282 (314) | alignment | ||
Range on Protein: 331-592
Range on HMM: 20-282/314.0
GIRLEAEYKNVSNEQQFSWDAARKAANKKKNRYGNIVTYDhSRVVLERVNGDeDSDYINASFIHGFdgtpRSYIASQGPPPPTFEGF----------WRM
...|. . . | . ... .|.. .|..|||| .|. .| .||.| ..... .|||||||...|| ...||.||| . |.. | |||
klllvlnrrslsvlpeltilvadlflnrdknryldilpad.nrvilpglpvs.gsdyinasyvdgf....lkfIatqgpleitvvdfreepvlyyngwrm
V--WEQNSQSIVM---------------------LTNLVELGktkchkywP--------EKTetyggvtvtlhqtevfadyvirtfilfREE---RAVRR
| ...|. ||| |..| ..| . . .| . |
vlrgdlnvrdivmsrdevladelsrLdaAlgKtpllildgng........neptaadlellk...........................eelydpelfer
MVRQFNFTVWPDKGVPqYATAVLAFRRKVRALnpRDAGPVIVHCSAGVGRTGAYIVIDAMLEQAKinrtVDIRNYLIALRKDRP-----HMVQTKEQYSF
.. .. . .|| ..| ...| . .... .. |||.|||.||.|||| ..|.. .. . . |... | .|. || ..... ||| |
lgikylripvpDgsap.lledfdeflefieea..dkggpvlvHCkaGkgRtgtfvvaaylmkllg....vsleealedvrlkRpinpnpgfieqleqyef
IHSAVLEALTC
|. |.||.|
ilealleylkf
|
|||||||||
subfamily_Cele-PTP-18_pd | Subfamily Cele-PTP-18 | 331-588 | 5.5e-37 | 122.1 | In-house | 21-285 (305) | alignment | ||
Range on Protein: 331-588
Range on HMM: 21-285/305.0
GIRLEAEYKNVSNEQQFS-WDAARKAANKKKNRYGNIVTYDHSRVVLervNGDEDSDYINASFIHGfDGTPRSYIASQGPPPPTFEGFWRMVWEQNSQSI
. | ||.... ..| | ..| ...|||| .. |. || | .| .|| | .. |. .| .| | | || | .... ..|
paglraefvamkrfndfekmkafkeaqeagknrykdvgcldnnrvkl...egpwpheyihanyvst.ptnpkrfictqaplektcadfwymclqdkveai
VMLTNLVELGKTKCHKYWPEKTE-------TYGGVTVTLHQTEV--F----ADYVIRTFILFREERAVRRMVRQFNFTVWPDKGVPQYATAVLAFRRKVR
|| ||.| | ||..|.. | . ..| . .. | . | .| .. . | | .. . |||.||| .|.| . | |
fmlcnllekgakkcleyfaskdkdvlefeekgqkisvkfessvtlkfrkdakakvtetvlviegpgekarkvthyhwidwpdrgvpaadlailellekar
ALNprdaGPVIVHCSAGVGRTGAYIVIDAMLEQAKINRTVDIR-NYLIALRKDRPHMVQTKEQYSFIHSAVLE
.. ||..||||||.||||. .... .|.| . .. | .|..| .|| .|| |.| .|.
psk....gpivvhcsagigrtgsvvmleyildqllagqiiedtdkilqkireqrnnsiqtdaqylfvhqviln
|
|||||||||
subfamily_Cele-PTP-11_pd | Subfamily Cele-PTP-11 | 331-596 | 2.7e-33 | 110.0 | In-house | 18-282 (312) | alignment | ||
Range on Protein: 331-596
Range on HMM: 18-282/312.0
GIRLEAEYKNVSNEQQFSWDAArKAANKKKNRYGNIVTYDHSRVVLervNGDEDsDYINASFIHgFDGTPRSYIASQGPPPPTFEGFWRMVWEQNSQSIV
.| ||| | | . | .| | ||| || .| | | |||. || | |.. | ....||| | ||... | ||.
pqqltkeykavgnivsdsecta.flkfkdlnrypniqcwdrgrftl...agden.fyihanfvk.ictkperfvctqgplentcthfwqlalslgstsii
MLTNLVELGKTKCHKYWPEKTetyGGvtVTLHQTEVFADYVIR--------TFILFREERAVRR------MVRQFNFTVWPDKGVPQYATAVLafrRKVR
.|. .|| | || || . | | | . |...|. | | . | . . ..... |||.|.|. . | | .
llcgfvedgsekcakyisdiv...gf..vdledhrvyteycteieiggkskdkithrvlkvvvkatgqesklnhyqwaswpdhgmpdscdtal...rlls
ALNpRDAGPVIVHCSAGVGRTGAYIVIDAMLEQAKINRTVDIRNYLIALRKDRPHMVQTKEQYSFIHSAVLEALTCGNTE
|.. .| ||| ||||||||||. ..|..|. . | .... .. ||||| |.. || . .||| | .
avk.kdkkpviahcsagvgrtgtlaliesmiaalrhprkqnvkdsfvllrkdrarsvrvfpqyvyalrcvleflyskgly
|
|||||||||
subfamily_Cele-PTP-4_pd | Subfamily Cele-PTP-4 | 332-587 | 7.8e-21 | 68.8 | In-house | 26-282 (302) | alignment | ||
Range on Protein: 332-587
Range on HMM: 26-282/302.0
IRLEAEYKNVSNEQQfSWDA-ARKAANKKKNRYGNIVTYDHSRVVLERvngdEDSDYINASFIHGFDGTpRSYIASQGPPPPTF---EGFWRMVWEQNSQ
.....|.|.... . . . .| |||. .. .|. .| || | .|.||| .. . | || | .| | . | |||||.... .
aevkkefkkidtmkv.dlekCkafkknlkknqsedvpildsnlvklea....epdsyvnaskvevPelt.rsiilaQlpkvdsedsveeFWrmvfqekiv
SIVMLTNLVELGKtKCHKYWPEKTE---TYGGVTVTLHQTEVFADYVIRTF-ILFREERAVRRMVRQFNFTVWPDKGVPQYATAVLAFRRKVRALNPRDA
|.|.| || | ....|.|.. .|| . | . | . . | .. |. . .. .| |..| ||. ... . || |..
svvilvgeeelkk.tlselfpkksgdykeygkmfvNnrkVekaeeektryviEvlPegcsnsvlanvyvltnWkqkkvpvkyaeliktaakvfakkikad
GPVIVHCSAGVGRTGAYIVIDAMLEQAKINRTVDIRNYLIALRKDRPHMVQTKEQYSFIHSAVL
.... |.|| || .. . .|. . . . | . ....|..||..|.. .|| ... |.|
entvivSknGaGRagafltlavaveklqkgkepnikeivksiRsqRpravdslkQyvslyiall
|
|||||||||
subfamily_PTPN12_pd | Subfamily PTPN12 | 333-590 | 2.5e-79 | 261.2 | In-house | 16-277 (290) | alignment | ||
Range on Protein: 333-590
Range on HMM: 16-277/290.0
RLEAEYKNVSNEQQFSWDAARKAANKKKNRYGNIVTYDHSRVVLERVNGDEDSDYINASFIHGFDGTpRSYIASQGPPPPTFEGFWRMVWEQNSQSIVML
.| .. .. .|...| .|..| |.||||| .|. ||.|||.|.. ...|.||||||.||.| .|. .|||.||| | | . ||||.||.| . .||.
klkklsekykaekvysteagekeenvkknrykDilPydksrvelskieeeegsdYinanfikgvegk.leyiaaqgPLpktlddfWrmiweknveivvma
TNLVELGKTKCHKYWPEKT---ETYGGVTVTLHQTEVFA-DYVIRTFILFREerAVRRMVRQFNFTVWPDKGVPQYATAVLAFRRKVRALNPRDAGPVIV
..|||||.||..||||.. ..| ..|||.. . . |..|||. . .. .|.|.||..| |||.|||. |. .|.. ..|| |. ... |..|
CrevelgkkkCerYWpeegeeelefgefevtleeekavdddflirtLkveaq..kesrkvyqfhYtaWPDhgvPssaksllelielvrelqesedaPlvv
HCSAGVGRTGAYIVIDA---MLEQAKINRTVDIRNYLIALRKDRPHMVQTKEQYSFIHSAVLEAL
||||||||||. |.|| .|.. ||. ..|. . .. |||.|. .|||||||.... ||.| .
hCsaGvGrtGtiiaidyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavaelv
|
|||||||||
subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 333-610 | 6.9e-79 | 260.4 | In-house | 35-311 (319) | alignment | ||
Range on Protein: 333-610
Range on HMM: 35-311/319.0
RLEAEYKNVSNEQQFSWD--AARKAANKKKNRYGNIVTYDHSRVVLERVNGDEDSDYINASFIHGFDgTPRSYIASQGPPPPTFEGFWRMVWEQNSQSIV
.||.|...... | | || |||..||...|...| |||..| | ||||||||. |. . |||.||| . | . ||||.||.|. .||
klevefrracklgvnladqtfanldqnkdknriinilafdknvvklerliGeefsdyinasfvtGyq.rkdkyiaaqGPldntladfWrmiweyncstiv
MLTnlvelgKTKCHKYWPEKT-ETYGGVTVTLHQTEVFADYVIRTFILFR-EERAVRRMVRQFNFTVWPDKGVPQYATAVLAFRRKVRALNPRDAG--PV
.|| | || .||| |. .... | .. | |.||.| . | . . | ..|| | |||.|||.|.. .. . .||| |. . . ..
llt......kdkcsqywplkivikeerfkvkvdsveetaeyvvrdielsedgkekdirkitqfhflGwpdvGvpdypsdlmrlvkkvrhltskenhrani
IVHCSAGVGRTGAYIVIDAMLEQAKINRTVDIRNYLIALRKDRPHMVQTKEQYSFIHSAVLEALTCGNTEIQSENFNQTTQKLA
.|||||||||||.|||.|..|.. | .. ||. |.. ||..|...|| || ||.||.|| |.... .| ..|.
vvhcsaGvGrtGvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysalleehlfghsdvampdfpayleels
|
|||||||||
subfamily_PTPRN_pd | Subfamily PTPRN | 333-589 | 1.5e-65 | 215.8 | In-house | 30-291 (297) | alignment | ||
Range on Protein: 333-589
Range on HMM: 30-291/297.0
RLEAEYKNVSNE--QQFSWDAARKAANKKKNRYGNIVTYDHSRVVLERVNGDEDSDYINASFIHGFDGTPRSYIASQGPPPPTFEGFWRMVWEQNSQSIV
|||.|.. . . .. . ..|.. | ||||. ....|||||| |.. . .|.|||||||.| | .|||.||| . | ||.||||| . ||
rlekewealcayeaepstkevakaeknvkknrskavlpydhsrvklkeeasaeksdyinasaildhdprapayiatqgplastvadfwqmvweqGvvviv
MLTNLVELGKTKCHKYWPEK-TETYGGVTVTLHQTEVFA-DYVIRTFILFREERAVRRMVRQFNFTVWPDKGVPQYATAVLAFRRKVRALNPRDAGPVIV
.||.| | | ..|..|||.. .|.|. | | ... ||..|.| | . | | || | ||..||| | ..| ||||| . |..|
nltrleeegvkqckrywpdeGsevyhiyevhlvsehiwcddylvrsfylknlqtsetrtvtqfhflswpeegvPasaksllefrrkvnksyrGrscpivv
HCSAGVGRTGAYIVIDAMLEQ-AKINRTVDIRNYLIALRKDRPHMVQTKEQYSFIHSAVLEA
|||.|.||||.||.|| .|.. .| . .|| | || .||..|.||.|. |. .|| |
hcsdGaGrtGvyilidlvlnrllkGvkeidiaatlehlrdqrpglvktkdqfefaltavaee
|
|||||||||
subfamily_Cele-PTP-6_pd | Subfamily Cele-PTP-6 | 333-589 | 6.7e-42 | 138.5 | In-house | 17-276 (307) | alignment | ||
Range on Protein: 333-589
Range on HMM: 17-276/307.0
RLEAEYKNVSNEQQFSWDAARKAANKKKNRYGNIVTYDHSRVVLErVNGdEDSDYINASFIhGFDGTPRSYIASQGPPPPTFEGFWRMVWEQNSQSIVML
.| |...... . . . || .|||| .. |..|.|.. ..| |||| | .. | |. .|..||| | || |. ... .|..||
alvdefrvlakktpegvtveafsantdknryqdvkcqdkgrivvk.fdg.lasdyihanyl.giaikpkkficaqgplentqysfwamaiqekvesviml
TNLVELGKTKCHKYWPE---KTETYGGVTVTLHQTEV------FADYVIRTFILFREERAVRRMVRQFNFTVWPDKGVPQYATAVLAFrrkVRALNpRDA
...||.| ||..||| .. ..| . |. ... . .| | . | ....... |||.|||| . . . . | . |
ckvielakikceqywpleegqklvfgeapntisvanlgakklapdedlinvttlkvdwaqksrtiqhlqwenwpdrgvpqinltainl...leavr.ydt
GPVIVHCSAGVGRTGAYIVIDAMLEQAK-INRTVDIRNYLIALRKDRPHMVQTKEQYSFIHSAVLEA
||.|||||||||.|. . | . .. |... . ||..|.. .||. || ..| .||
npvvvhcsaGvGrsGtivaislvqdkmiaGinckdmkklveelrsqrhyaiqteaqylylhrvlley
|
|||||||||
0046845 | (Phosphotyrosine protein) phosphatases II | 334-595 | 5.9e-92 | 303.3 | In-house | 2-279 (284) | alignment | ||
Range on Protein: 334-595
Range on HMM: 2-279/284.0
LEAEYKNVSNEQQF---SWDAARKAANKKKNRYGNIVTYDHSRVVLERVNGD-EDSDYINASFIHGFD----GTPRSYIASQGPPPPTFEGFWRMVWEQN
||.|.. . . . . |...|.. .|..|||| .|. ||||||.| ...|| |||||||||...|.| ... .|| ||| | |.| |||||||||
leeefeellsltvklllslsvallpenlsknRykdilpydhsRVklksldgdledsdYinAsyvdgydldltyikkkfIatqgPlpntvedFwrmvweqn
SQSIVMLTNLVELGKTKCHKYWPEK--TETYGGVTVTLHQTEVFADYVIRTFILFREE-RAVRRMVRQFNFTVWPDKGVPQYATAVLAFRRKVRALNP--
.. |||||.||| |..||..|||.. . |||..|||| .||. ||..||. | ... |.|..| .| ||| |||.... .|.| |.|| |..
vrvIVmltelvengrekcaqYwplegevltygdftvtllseevkddytvrtleltnlgytgesrtvthfhytswpdhgvppspedlleflrlvrellenl
RDAGPVIVHCSAGVGRTGAYIVIDAMLEQAKINR---TVDIRNYLIALRKDRPHMVQTKEQYSFIHSAVLEALTCGNT
. ||..|||||||||||..|..| .||| . .. .||. ... ||. ||.|||| ||| |.. |.||.| ...|
pgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvqtleqyrfvyealleylklklt
|
|||||||||
subfamily_PTPN5_RR_pd | Subfamily PTPN5_RR | 334-588 | 1.9e-70 | 232.1 | In-house | 7-266 (274) | alignment | ||
Range on Protein: 334-588
Range on HMM: 7-266/274.0
LEAEYKNVSNEQqfSWDAARKAANKKKNRYGNIVTYDHSRVVLERVNGDE-DSDYINASFIHGFDGTPRSYIASQGPPPPTFEGFWRMVWEQNSQSIVML
||.|. .. . . . . . ...|||| .|. ..|||.||. .... ||.|||| .|.|.|.. . |.| ||| | | . ||||......| ||||
lekeflelPlnf..dqeeldvfgsqtknryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntvadfWrmiyqeevqvivml
TNLVELGKTKCHKYWPEKTET-----YGGVTVTLHQTEVFADYVIRTFILFREERavRRMVRQFNFTVWPDKGVPQYATAVLAFRRKVRALNPR---DAG
|.| | ..||..|.|..... ||.| .. ... || .|...| || .| | . .| |||. .|. |...| . ..|. . . ..
tklkeaneqkCavyfPdaedyeiserygdveikvekiverndysvrklvlkyler..ersvkhywytdWPdhksPddantlldlvleveesreeenakla
PVIVHCSAGVGRTGAYIVIDAMLEQAKINRTVDIRNYLIALRKDRPHMVQTKEQYSFIHSAVLE
||.||||||.||||..| |. . | . . .||. . || || ||||.||| .|| |. .
pvvvhCsaGiGrtGcfiaisiavrqlreeivvdvlkivcnlrldrGGmvqtseqyelihralcl
|
|||||||||
subfamily_Cele-PTP-8_pd | Subfamily Cele-PTP-8 | 334-595 | 1.7e-34 | 114.1 | In-house | 21-276 (288) | alignment | ||
Range on Protein: 334-595
Range on HMM: 21-276/288.0
LEAEYKNVSNEQQFSwDAARKAANKKKNRYGNIVTYDHSRVVLErvngdEDSDYINASFIHGFDGTPRSYIASQGPPPPTFEGFWRMVWEQNSQSIVMLT
|. ||.. || . . || ..|| |. | .|| |. .|.|. |. . .| | .| | | | .|.|. |.. . ||||.
lkkeyrdspneasid.iidsfianptrdryenlprcditrvkls.....ddpdfyiaanvvssakykrrlicaqaPlngtieelWkmllesdveyivmlc
NLVELGKTKCHKYWPEKTET---YGG-VTVTLHQTeVFADYVIRTF-ILFREERAVRRMVRQFNFTVWPDKGVPQYATAVLAFRRKVRALNprdaGPVIV
.|.|.|| | .|.| | .| ||. .. . | ... . .| . .|.. . |.|.|||. . | . ...|. |..|
ellekGkeksaeyfPsklGekarigrlctvvkkkr.adidklvkvsllriskegeekvivkilhlleWdddgvPenylsplrllevlkslq....kPivv
HCSAGVGRTGAYIVIDAMLEQAKINRTVDIRNYLIALRKDRPHMVQTKEQYSFIHSAVLEALTCGNT
|.||||||||. |.| .||..... . ||. | ||..| . .||. || ..| ||| |
hssaGvGrtgtlililialeslrlddflgirsllaklreerfkaiqtemqylyvhrcvleelllkky
|
|||||||||
subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 334-513 | 4.7e-32 | 106.0 | In-house | 9-191 (297) | alignment | ||
Range on Protein: 334-513
Range on HMM: 9-191/297.0
LEAEYKNVSNEQQ-FSWDAARKAANKKKNRYGNIVTYDHSRVVLERVNgdEDSDYINASFIHGFD-GTPRSYIASQGPPPPTFEGFWRMVWEQNSQSIVM
||||. . .|.. |. .|.. . .|||| .|...| .|| | || ..||||| .. | .. || .||| | . ||..|.||. . |||
leaekdllldeargesfssakrnsslrknryrdilatddtrvkllrvi..terdyinadyvvfpdeeadlkyilaqGplsatvddfwtlvaeqdvrvivm
LTNLVELGKTKCHKYWPEKTE---TYGGVTVTlHQTEVFAD--YVIRTFiLFREERAVRRMVRQFNFTVWPDKGVPQYATAVLAFRR
...| | |. || |||. . . | | | . ... . || | | |. .|.|| .| |||.||| . |.
vaklqedGrdkcapywpsvvqerlkagdvvve.flsstsdefdrvilte.lqliyrsesrvvrhvqflswpdhGvpsdledlvrfqa
|
|||||||||
DSPc_SM00195 | 335-590 | 4.3e-83 | 274.0 | In-house | 3-262 (263) | alignment | |||
Range on Protein: 335-590
Range on HMM: 3-262/263.0
EAEYKNVSNEQ-QFSWDAARKAANKKKNRYGNIVTYDHSRVVLERVNGDEDSDYINASFIHGFdGTPRSYIASQGPPPPTFEGFWRMVWEQNSQSIVMLT
..|.... ... . . . |.| .||.|||| ||. |||.|| |.. ...|.||||||..| | ...||| ||| | |.| |||||||.... |||||
keefekleestspketteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikga.nkkkkyIatQgPlpstvedFWrmvweekvkiivmlt
NLVELGKTKCHKYWPEK---TETYGGVTVTLHQTEVFA-DYVIRTFILFREERAVRRMVRQFNFTVWPDKGVPQYATAVLAFRRKVRALNPRDAGPVIVH
. .| ||.||..||||. .||.| ..|.| ..| ....||. | |.. | |.|.... |||.|||. .. ||.. |.|. . . ||..||
eeeengkekcdrywpeesggketfgkisvklvevekkkdeiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkkskstssgpivVh
CSAGVGRTGAYIVIDAMLEQAKINRTVDIRNYLIALRKDRPHMVQTKEQYSFIHSAVLEAL
|||||||||....|| .|.. . . .||| . . .||| ||.||||.|||.||. |.||..
CsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaileyi
|
|||||||||
PTPc_SM00194 | 335-590 | 4.3e-83 | 274.0 | In-house | 3-262 (263) | alignment | |||
Range on Protein: 335-590
Range on HMM: 3-262/263.0
EAEYKNVSNEQ-QFSWDAARKAANKKKNRYGNIVTYDHSRVVLERVNGDEDSDYINASFIHGFdGTPRSYIASQGPPPPTFEGFWRMVWEQNSQSIVMLT
..|.... ... . . . |.| .||.|||| ||. |||.|| |.. ...|.||||||..| | ...||| ||| | |.| |||||||.... |||||
keefekleestspketteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikga.nkkkkyIatQgPlpstvedFWrmvweekvkiivmlt
NLVELGKTKCHKYWPEK---TETYGGVTVTLHQTEVFA-DYVIRTFILFREERAVRRMVRQFNFTVWPDKGVPQYATAVLAFRRKVRALNPRDAGPVIVH
. .| ||.||..||||. .||.| ..|.| ..| ....||. | |.. | |.|.... |||.|||. .. ||.. |.|. . . ||..||
eeeengkekcdrywpeesggketfgkisvklvevekkkdeiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkkskstssgpivVh
CSAGVGRTGAYIVIDAMLEQAKINRTVDIRNYLIALRKDRPHMVQTKEQYSFIHSAVLEAL
|||||||||....|| .|.. . . .||| . . .||| ||.||||.|||.||. |.||..
CsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaileyi
|
|||||||||
subfamily_PTPN6_pd | Subfamily PTPN6 | 336-588 | 9.9e-79 | 259.5 | In-house | 30-295 (306) | alignment | ||
Range on Protein: 336-588
Range on HMM: 30-295/306.0
AEYKNV---SNEQQFSWDAARKAANKKKNRYGNIVTYDHSRVVLErVNGDEDSDYINASFIH-GFDGTPRSYIASQGPPPPTFEGFWRMVWEQNSQSIVM
|.... .....| . ..|. ||.|||| ||. .||.||.|. .. .||||||..|. . |. .||||.|| . | . ||||||..||. |||
eefeelqqeeakkllsrkegakpenkeknryknilPfDhtrvilk.epsvpgsdyinanyikkevkgsdksyiatqgclettvsdFWrmvwqensrvivm
LTNLVELGKTKCHKYWPEK--TETYGGVTVTLHQTEVFADYVIRTFILF-REERAVRRMVRQFNFTVWPDKGVPQYATAVLAFRRKVRA----LNPRDAG
.|. || || || .|||.. .|.|| ..|| . . |||..|.. . ... | |.|..|..|||.|||. |||.| ..|.. |. ..||
ttkevErgkekCarYWPdeeekeeyGkisvtnvseksladYilRelsvskkkkkkeerevfqyhfksWPdhgvpkdpgavLdfledvnrkqeeleeaeag
PVIVHCSAGVGRTGAYIVIDAMLEQA---KINRTVDIRNYLIALRKDRPHMVQTKEQYSFIHSAVLE
|..||||||.||||..||||..|.. ... .||.. .|. | .|||..|| |.. |. .
pivvhCsaGiGRtGtfiviDillkliekkgldadidiqklvksvreqrsglvqteqqykfvykaikk
|
|||||||||
subfamily_PTPN13_pd | Subfamily PTPN13 | 336-591 | 2.9e-68 | 225.1 | In-house | 15-270 (273) | alignment | ||
Range on Protein: 336-591
Range on HMM: 15-270/273.0
AEYKNVSNEQ-QFSWDAARKAANKKKNRYGNIVTYDHSRVVLERVNGdedsdYINASFIHGFDGT-PRSYIASQGPPPPTFEGFWRMVWEQNSQSIVMLT
|.|.. . . . . . ..|..||.|||| |.. ||..|| |. | |||||.|. | .|||.||| | | . ||.|||||... |.|.|
eefkelrelkpldtcevgkkkenkdknryrnvlPydetrvklgdegg.....yinaslikvpvgkdeyeyiacqGPlPetvkdfwqmvweqkaeviamvt
NLVELGKTKCHKYWPEKTE----TYGGVTVTLHQTEVFADYVIRTFILFREERAVRRMVRQFNFTVWPDKGVPQYATAVLAFRRKVRALNPrDAGPVIVH
. .| || |||.||||... .. ..|.| ... ..|.|.. . | . | | ..||. ||| |||. |. .| | ..|| |. ||||..||
lekekgkvkchrywPesknkklkvsnrlevellkvqkldgfvvralavkdsesgesrevahlnfvkwPdhgvPssaaellqfvaevrrlqt.dagPivvh
CSAGVGRTGAYIVIDAMLEQAKINRTVDIRNYLIALRKDRPHMVQTKEQYSFIHSAVLEALT
||||.||.|..|.||..|. . .. .|... . ||. | .||||.|| |.. |.||.|.
csaGiGrsGtlitidvvlglierdkefdvkeivrklreqrqgvvqtkdqyifvykailevlk
|
|||||||||
subfamily_PTPN14_pd | Subfamily PTPN14 | 336-590 | 3e-57 | 188.9 | In-house | 27-296 (300) | alignment | ||
Range on Protein: 336-590
Range on HMM: 27-296/300.0
AEYKNVSNEQ-QFSWDAARKAANKKKNRYGNIVTYDHSRVVLERVNgDEDSDYINASFIHG-FDGTPRSYIASQGPPPPTFEGFWRMVWEQNSQSIVMLT
.|| ...... . ..|. |..|||. ... |...|| | . .....||||| |. |. ||||..||| . | . ||.|||||. | |||||
teyeripkkredallstaklpenaeknrfkdvlPyednrvelsptk.enstgyinassikvsvggkersyivaqgPleltvqdfWqmvWeqgvqlivmlt
NLVELGKTKCHKYWPEK-----TETYGGVTVTLHQTEVFADYVIRTFILFREERAVRRMVRQFNFTVWPDKGVPQYATAVLAFRRKVRALNPR-------
. | ||.|..||.|.. | ..| || . .| .. ... | .| | . .| |||.|||. . | . ..|... .
eeeedgkeksfkyfPkleskkktvefgkfkvttkfsedsdsvittglklkhlpskeertvwhlqytDWpdhgvPeDvkgflsyLeevqsvrrktnseves
--DAGPVIVHCSAGVGRTGAYIVIDAMLEQAKINRTVDIRNYLIALRKDRPHMVQTKEQYSFIHSAVLEAL
||.||||||||||| |. | ... . |...||.. | ||. | ..||| || |....... |
keskPPvlvhCsaGvGrtGvlilsdlliatlehneeidikkvlarLreqrmllvqtlaqYkfvYkvlikyl
|
|||||||||
subfamily_PTPN1_pd | Subfamily PTPN1 | 337-596 | 5.3e-66 | 217.3 | In-house | 11-279 (290) | alignment | ||
Range on Protein: 337-596
Range on HMM: 11-279/290.0
EYKNVSNEQ-QFSWDAARKAANKKKNRYGNIVTYDHSRVVLERvngdEDSDYINASFIHgFDGTPRSYIASQGPPPPTFEGFWRMVWEQNSQSIVMLTNL
|.....| .|. .|.. .|...||| .. |||||..||| .| ||||||... .. |||| .||| | | . ||.|||||.|...||| ..
iyldirkeasdfptreaklpenrnlnryrdvspydhsrikler....adndyinaslve.leeakrsyiltqGPlpntvdhfWqmvWeqkskavvmlnkv
VELGKTKCHKYWPEKTE----TYG--GVTVTLHQTEVFADYVIRTFILFREERAVRRMVRQFNFTVWPDKGVPQYATAVLAFRRKVRAL--NPRDAGPVI
|| ...||..|||.. | .. ..|.| ..|. |..|.. | . | . .| .| ||| |||. .| | | ||| .| ||..
vekeqikcaqywPqgeeekellledtklkvkliseerksyytvrllelenlktqetreilhfhyttwpdfgvpespaaflkflfkvresGslssdvGpav
VHCSAGVGRTGAYIVIDAMLEQAK---INRTVDIRNYLIALRKDRPHMVQTKEQYSFIHSAVLEALTC--GNTE
.|||||.||.|.....|..| . . .|||.. |..||| | ..||..| | . |.|| . |..
ihcsaGiGrsGtfclvdtclvliekkddlssvdikkvllelrkyrlGliqtadqlrfsylaileGakvikgdss
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 337-516 | 7.4e-36 | 118.4 | In-house | 10-191 (319) | alignment | ||
Range on Protein: 337-516
Range on HMM: 10-191/319.0
EYKNVSneQQFSWDAARKAANKKKNRYGNIVTYDHSRVVLERVNGDEDSDYINASFIHGFDGTPRSYIASQGPPPPTFEGFWRMVWEQNSQSIVMLTNLV
|.... | . . .. |.|.|. |.| ..||||.|. |. . |..||.. |.| .| ||||.| . . |||.||||.|. || ||.|
efrdlP..qliaradevPvtskdksrvinvvPlPetrvvlqrigdddkdeyldasyvrGyddapnsyiaaqvsledsssdfwrtvweqqsrvivqltdls
ELGKTKCHKYWPEK-----TETYGGVTVTLHQTEVFADYVIRTFILFREERAVRRMVRQFNFtVWPDKGVPQYATAVLAFRRKVR
||| .| .|.| | |..|| . ||| . || |.| |..| | .. | . . . |.. .|| .|..| .||
elGikvcaeylPtketldntslyGdilvtlkgrevkdryaistlllkrvdkeesrelthywy.kwleaevPaeeaaliamllevr
|
|||||||||
subfamily_Cele-PTP-14_pd | Subfamily Cele-PTP-14 | 337-598 | 7.3e-33 | 108.4 | In-house | 32-297 (310) | alignment | ||
Range on Protein: 337-598
Range on HMM: 32-297/310.0
EYKNVSNEQQFSWDAARKAANKKKNRYGNIVTYDHSRVVLErVNGDEDSDYINASFIHGfDGTPRSYIASQGPPPPTFEGFWRMVWEQNSQSIVMLTNLV
.|... .|. | . .|||| ..| | ||| |. .. ||| | ... . ..| |||| | ||||.... ..||..| . .
qyrkldakqdssltyeaykkymhknrysdvvcldtsrvklk.idksryedyihanyvkt.nylrstficsqgplqhtiidfwrmifqeraesilllckvg
ELGKTKCHKYWPE--KTETYGGVTVTLHQtEVFADY----VIRTFI----LFREERAVRRM--VRQFNFTVWPDKGVPQYATAVLAFrrkvRALNPRDAG
| |. || ||| ||||| . || | .. . ||. |. | . | .. |||.|||. . | | |
eegrpkcvgywpslgvtetygcirvtnls.esseefeicnlavtfvpdnvpvdeqpanlkelrvslikwpnwpdrgvpdekchtvpq....rllaqvrhg
PVIVHCSAGVGRTGAYIVIDAMLEQAKINRTVDIRNYLIALRKDRPHMVQTKEQYSFIHSAVLeALTCGNTEIQ
|..||||||..|... . .. ..... ||. . |.|.| .||. || .|. . ... |.||.
pcvvhcsagkdrlyvvvalklkidkldrglkvdaeevktellksraiciqtelqyliidrvri.ifargeteva
|
|||||||||
subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 338-588 | 4.4e-67 | 220.9 | In-house | 1-262 (270) | alignment | ||
Range on Protein: 338-588
Range on HMM: 1-262/270.0
YKNVSNEQQFSWDAARKAANKKKNRYGNIVTYDHSRVVLERVNGDEDSDYINASFIHGFDGTPRSYIASQGPPPPTFEGFWRMVWEQNSQSIVMLTNLVE
.|....|.. . | | .|| ||| .|. ..||.||... |. . |||| ...|||| ...|||..|| | | . ||||.||.....|||.|.|.|
fkeldkeetsesdlpeaargkklnRyadiLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleE
LGKTKCHKYWPEKTET-----YGGVTVtLHQTEVFADYVIRTFILFREERAVRRMVrQFNFTVWPDKGVPQYAT------AVLAFRRKVRALNPRD--AG
|..|| .|||..... .| ..| | ..|. .. |.| . .|. ||.| | .. |||.|||. . .|. |.||. . . |.
kgrkkCerYWpaepkekvkledgkikv.lalseekeegyiltrlrleekgeerrlv.HfwyntWpdhgvpreedsslstdqllkmlravrrsekeldkae
PVIVHCSAGVGRTGAYIVIDAMLEQAKINRTVDIRNYLIALRKDRPHMVQTKEQYSFIHSAVLE
|..||||||||||| |..| ... . .. ||. . . .|||||. .||. ||| |.. ||.|
PllvHcsaGvgRtGtlialDiavrlLeetkkvdvlaiieelRkdRmalvqhpeqyeflykavve
|
|||||||||
subfamily_PTPN23_pd | Subfamily PTPN23 | 338-589 | 4.3e-59 | 194.7 | In-house | 21-279 (288) | alignment | ||
Range on Protein: 338-589
Range on HMM: 21-279/288.0
YKNVS-----NEQQFSWDAARKaaNKKKNRYGNIVTYDHSRVVLErvngDEDSDYINASFIHGFDGTPRSYIASQGPPPPTFEGFWRMVWEQNSQSIVML
.|.. . ...| .|.. . .|||. .|. |||.||.|. .. |||||||... . ..||.|.| ..| ||.||.|| |. ||||
fkeleqkqdkearkrsiaiakl..yseknrsrdilPyDhnRvklr....gskDDYinAsfvkdlspgcPdfiatqaPlqstlnDFWlmvyeqkssviVml
TNLVELGKTKCHKYWPEK---TETYGGVTVTLHQTEVFADYVIRTFILFREERAVRRMVRQFNFTVWPDKGVPQYATAVLAFRRKVRA----LNPRDAGP
.. ||||.|...||||. |...| ..|||.... .| |...| .. ..|. ..| ||. |||. .|.| .|.. . . |
lskeelgkpkvdrYwPedkgetvkfgdlsvtlksvretethvervlkletldadavksvshlqltsWpelGvPasPetllqfldevesayeavqrksktP
VIVHCSAGVGRTGAYIVI-DAMLEQAKINRTVDIRNYLIALRKDRPHMVQTKEQYSFIHSAVLEA
..|||||||||||.. .. |. | | | .|| . . ||..| .|||.|||. | .|||||
lvvhCsaGvgRtgvfalvyaavrelekgnglldiiqvvsrlreqRrfmvqekeqlkfsyeavlea
|
|||||||||
subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 339-587 | 2e-57 | 189.2 | In-house | 20-274 (287) | alignment | ||
Range on Protein: 339-587
Range on HMM: 20-274/287.0
KNVSNEQQFSWDAARKAANKKKNRYGNIVTYDHSRVVLErVNGDEDSDYINASFIHGFDGTpRSYIASQGPPPPTFEGFWRMVWEQNSQSIVMLTNLVEL
|. |. . . || . |. |||||.... .|..||.| .|. |||||| .. .. ..||.||| . | |||.|.|..| |....| ||
kedsesstatfkaaeelaavkknryadvlPiddtrvlls.aegelGsdyinanyvasytdd.eafiaaqgPiaatvrdfwravletrsasvitmtrevee
GKTKCHKYWPEKTE--TYGGVTVT-LHQTEVFADYVIRTFILFREERAVRRMVRQFNFTVWPDKGVPQYATAVLAFRRKV-----RALNPRDAGPVIVHC
.. ||.|||||. || .|. | .. .| .|.. | | |.|.|... ||||... | ... | .| | . ..||..||.
arlkcykywPerevPmrvGGysvvlldydikePeygvralrlidletrearvvkqldllswPdkvlaPtavglirfvldvkqhielardasevGPlvvhd
SAGVGRTGAYIVIDAMLEQAKINRTVDIRNYLIALRKDRPHMVQTKEQYSFIHSAVL
..|.||.| .. . ..... . ||. . .| ||. | .||. |. .. |.
dvGiGrsGillatlvlvsrledlGrvdvaavvirlreyraalvqavvqlrllyealv
|
|||||||||
0036941 | (Phosphotyrosine protein) phosphatases II | 342-597 | 2.8e-89 | 294.6 | In-house | 24-284 (297) | alignment | ||
Range on Protein: 342-597
Range on HMM: 24-284/297.0
SNEQQFSWDAARKAANKKKNRYGNIVTYDHSRVVLervnGDEDSDYINASFIHGFdGTPRSYIASQGPPPPTFEGFWRMVWEQNSQSIVMLTNLVELGKT
.. ..|...|.. .|..|||| .|. |||.||.| .||.|||||||.. |. . .| .|| ||| | |.| |||||||||...|||||.|||||.
pllllgslsvallpenleknRykdilpydhtRVkl....ddegsdYinAsyvdgy.dlkrkfIatqgPlpntvedFWrmvweqnvtvIvmltelvelgre
KCHKYWP---EKTETYGGVTVTLHQTEV--FADYVIRTFILFREERAVRRMVRQFNFTVWPDKGVPQYATAVLAFRRKVRALNPR--DAGPVIVHCSAGV
||..||| ... |||..|||| .|| ..||..||. . . |.|..| .| ||| |||.... .|.| ..|| .. . |||.|||||||
kcaqywpleegesltygdftvtllsvevvllddytlrtlevtdtgngesrtvthfhytgwpdhgvpespaslldfielvrkvlkllpsggpvlVHCsaGv
GRTGAYIVIDAMLEQAK---INRTVDIRNYLIALRKDRPHMVQTKEQYSFIHSAVLEALTCGNTEI
||.|..|..| ||.| . ....||| ... ||. ||..||| ||| |.. |.|| | ...| .
gRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyeallellkkkltke
|
|||||||||
subfamily_PTPN3_pd | Subfamily PTPN3 | 345-589 | 8.2e-71 | 233.2 | In-house | 29-274 (280) | alignment | ||
Range on Protein: 345-589
Range on HMM: 29-274/280.0
QQFSWDAARKAANKKKNRYGNIVTYDHSRVVLErvngDEDSDYINASFIH-GFDG--TPRSYIASQGPPPPTFEGFWRMVWEQNSQSIVMLTNLVELGKT
.. . .||||..| .|||| .|..||. || |. ....|||||... .. . |||.||| . | . ||.|||||.|. |||||.||| |..
pglaisaarkpenlsknryrdilpydatrvklk....esetdyinanyvnmeipstglvnryiatqGPlaktatdfWqmvweqksslivmlttlverGrv
KCHKYWPEKTE--TYGGVTVTLHQTEVFADYVIRTFILFREERAVRRMVRQFNFTVWPDKGVPQYATAVLAFRRKVRALNPRDAGPVIVHCSAGVGRTGA
|||.||||... .||. .|...... ||.| ..| ..| .|.. |. .. |||.|||. .. .| | ..||.| . ||.||||||.||||
kChqyWPetedeleygefsvkcekedetksyvlrelvlkdketkeerkilqlqylaWpdhgvPddsadflefvervrklrsgkeePvvvhCsaGigrtGv
YIVIDAMLEQAKINRTVDIRNYLIALRKDRPHMVQTKEQYSFIHSAVLEA
.|... | ... | . . . .| | .|||..|| |. |.|..
lilletalalieaaepvypldivrtmrdqramlvqtasqykfvCeailkv
|
|||||||||
subfamily_Sponge-PTP-2_pd | Subfamily Sponge-PTP-2 | 346-455 | 5.8e-11 | 35.6 | In-house | 16-92 (169) | alignment | ||
Range on Protein: 346-455
Range on HMM: 16-92/169.0
QFSWDAARKAANKKKNRYGNIVTYDHSRVVLERVNGDEDSDYINAsfihgfdgtprsyiasqgpppptfegfwRMVWEQNSQSIVMLTNLvelgkTKCHK
.. | ..|. ||| .. | || |.|| | |||||| ||.|| |. ||.| .
eynnfmaeltcnetknrpagplapshtrvklqrvmedlgsdyina............................rmiwetnasvivvlgdt.....ddknn
YWPEKTETYG
.|||| .
fwpekedyql
|
|||||||||
subfamily_Sponge-PTP2_pd | Subfamily Sponge-PTP2 | 347-454 | 9.1e-11 | 34.9 | In-house | 16-90 (169) | alignment | ||
Range on Protein: 347-454
Range on HMM: 16-90/169.0
FSWDAARKAANKKKNRYGNIVTYDHSRVVLERVNGDEDSDYINAsfihgfdgtprsyiasqgpppptfegfwRMVWEQNSQSIVMLTNLvelgkTKCHKY
. | ..|. ||| .. | || |.|| | |||||| ||.|| |. ||.| . .
ynnfmaeltcnetknrpagplapshtrvklqrvmedlgsdyina............................rmiwetnasvivvlGdt.....ddknnf
WPEKTETY
|||| .
wpekedyq
|
|||||||||
0045098 | (Phosphotyrosine protein) phosphatases II | 348-593 | 2.5e-77 | 255.3 | In-house | 24-275 (278) | alignment | ||
Range on Protein: 348-593
Range on HMM: 24-275/278.0
SWDAARKAANKKKNRYGNIVTYDHSRVVlervngdedsDYINASFIHGFdgtPRSYIASQGPPPPTFEGFWRMVWEQNSQSIVMLTNLVELGKTKCHKYW
.. | . |..|||| .|. ||||||. ||||||.|.|. |. .|| ||| | |.. ||||.||.....|||||.|||||. ||..||
eitpalylgnldknRykdilpydhsrVk..........dYINAsyidgy...pkkfIatqgPlpstvadfwrmlwelgitvivmltelvelgrekcaqyw
PEKT-ETYGGVTVTLHQTEVFADYVIRTFILFRE----ERAVRRMVRQFNFTVWPDKGVPQYA--TAVLAFRRKVRALNPR-------------DAGPVI
||. .|||..|||| ..||. ||..||... | | |...... ||| ||| . . .| . . .|. . . . |||.
peggsltygdftvtllseevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllsslllldsggpvl
VHCSAGVGRTGAYIVIDAMLEQAkiNRTVDIRNYLIALRKDRPH-MVQTKEQYSFIHSAVLEALTCG
|||||||||||...... |||. ...||. ... ||. ||. .||..||| |.. ..|| | .|
VHCsaGvgRtGtlvaaylmlell..eggvdlleavkelrsqRpglavqnleqyrflyefllelllrg
|
|||||||||
subfamily_Sponge-PTP5_pd | Subfamily Sponge-PTP5 | 348-605 | 2.6e-55 | 182.3 | In-house | 24-281 (283) | alignment | ||
Range on Protein: 348-605
Range on HMM: 24-281/283.0
SWDAARKAANKKKNRYGNIVTYDHSRVVLERVNGdedsDYINASFIH--GFDGTPRSYIASQGPPPPTFEGFWRMVWEQNSQSIVMLTNLVELGKTKCHK
. | | ||.|||. .||..| || |. . |||||.|| . . ||..|.| | ||.||.... .|||||.| | . || .
dadiasadenkrknrnqeivpadqwrvelksesr....dyinavfipvsksykqdkkyiiaqsPldrtvvdfWkmvfdekitaivmltklqedlrikCsq
YWPEK-TETYGGVTVTLHQTEVFADYVIRTFILFREERAVRRM-VRQFNFTVWPDKGVPQYATAVLAFRRKVRALNPRDAGPVIVHCSAGVGRTGAYIVI
|||.. .| || ||||.. ..|. ..| . | . . . . | . | ... | . . . ||..||||.|.|||...| .
yWPkrGsedyGeftvtlrkettsnsfiikelllrvnssakstlllahyqvidWleygeqaiinslvkfnkvislqteskkgPivvhCstgiGrtavfiaa
DAMLEQAKINRTVDIRNYLIALRKDRPHMVQTKEQYSFIHSAVLEALTCGNTEIQSENFNQT
| ...|. . ||. . . .|..|. .|||..|| ..| .||| ||.|.| .. .|
sasvkdaltesvvdvfavvkimreqrmmavqtldqyklvhelvleqalcgdtqiaavdlqst
|
|||||||||
subfamily_eak_pd | Subfamily eak | 348-515 | 2.8e-16 | 53.8 | In-house | 43-207 (332) | alignment | ||
Range on Protein: 348-515
Range on HMM: 43-207/332.0
SWDAARKAANKKKNrYGNIVTYDHSRVVLERVNGDEDsDYINASFIhGFDGTPRSYIASQGPPPPTFEGFWRMVWEQNSQSIVMLTNLVELGKTKCHKYW
| ... . ..| .|| ||. | | ... ||||| . | | || . . ||.|| ||.| .||.| . |||. | ||.
sisetarleavnrn.vvkivpydrylvrltssqlnrl.Gyinasla.efsevGrkyiltGiasedkvfafwqmvleqkspaivqlledvelkleksdkyf
PEKT---ETYGGVTVTLHQTEVFADYVIRTFILFREERAVRrmVRQFNFTVWPDKGVPQYAtAVLAFRRKV
|.|| .| . |. . . . | ..| . . . | | ... | . .|.| ||.|. .
pdktreelkfGildverkefvkrniletrllelskGnethr..vlhykvfGwtettlpkye.dflalrkvm
|
|||||||||
0040439 | (Phosphotyrosine protein) phosphatases II | 349-590 | 1.5e-80 | 265.7 | In-house | 3-246 (249) | alignment | ||
Range on Protein: 349-590
Range on HMM: 3-246/249.0
WDAARKAANKKKNRYGNIVTYDHSRVVLERVNGDEDSDYINASFIHGFDGTPRsYIASQGPPPPTFEGFWRMVWEQNSQSIVMLTNLVELGKTKCHKYWP
.. |.. .||.|||| .|. ||||||.|. ..| ..|||||||.|.|.. ..| .|| ||| | |.| ||||.||.....|||||.|||||. ||..|||
ysvallpenkdknrypdilpydhsrvklsilpglflsdyinAsyidgyyikrr.fiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqywp
-EKTETYGGVTVTLHQTEVFADYVIRTFILFREERAVRRMVRQFNFTVWPDKGVPQYATAVLAFRRKVRALNPR--DAGPVIVHCSAGVGRTGAYIVIDA
... .||..|||| ..||..||..||. | . . |.|.....| ||| |||.. .|.| ..|| . . . |||.|||||||||||..|...
lggsleygdftvtllsvevkddytvrtleltnlydgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtfiaayl
MLEQAKINRTVDIRNYLIALRKDRPHMVQTKEQYSFIHSAVLEAL
|||| . ...||. ... ||. ||..||. ||| |.. |.|| |
mleqlekelgvdleeavkllrsqRpgavqnpeqyrflyeallell
|
|||||||||
0037934 | (Phosphotyrosine protein) phosphatases II | 349-588 | 1.4e-74 | 246.0 | In-house | 2-240 (243) | alignment | ||
Range on Protein: 349-588
Range on HMM: 2-240/243.0
WDAARKAANKKKNRYGNIVTYDHSRVVLervngdEDSDYINASFIHGFDgtpRsYIASQGPPPPTFEG----FWRMVWEQNSQSIVMLTNLVELGKTKCH
. |.. .|..|||| .|..||||||.| |.||||||..| ... | .||.||| | |.| ||||.||.....|||||.|||||. ||.
fsiallpenlsknrysdilpydhsrvkl......egsdyinanliyvtp...r.liatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekca
KYWPEKTeTYGGVTVTLHQTEVFADYVIRTFILFREE-RAVRRMVRQFNFTVWPDKGVPQYATAVLAFRRKVRAL--------NPRDAGPVIVHCSAGVG
.|||... |||..|||| ..|...||..||. | . . . |.|... .. ||| |||. . .|.| ..||. . . |||.||||||||
qywpgev.tygdftvtllseehlddytvrtlllenldlddltrlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvg
RTGAYIVIDAMLEQAkinrTVDIRNYLIALRKDRPH-MVQTKEQYSFIHSAVLE
|||..|... ||.. .||. ... ||. ||. .||| .|| |.. |.||
RtGtliaaylmllll....gvdleeavkllreqRpgkavqtpsqyrflyealle
|
|||||||||
subfamily_Cele-PTP-10_pd | Subfamily Cele-PTP-10 | 349-588 | 4.9e-36 | 118.9 | In-house | 46-287 (305) | alignment | ||
Range on Protein: 349-588
Range on HMM: 46-287/305.0
WDAAR-KAANKKKNRYGNIVTYDHSRVVLERVNgdeDSDYINASFIHGFDGTPRSYIASQGPPPPTFEGFWRMVWEQNSQSIVMLTNLVELGKTKCHKYW
..| . .. |||| .. |.| | |.. . |||| | .. . .|..||| | . || || ... . |||| . ||||| || .||
fnanqsadiaitknryqdvpcqdqsavkldkps...psdyihanyvgcpmipekrficaqgpldqtidefwwmviqnkveqivmlcktvelgklkcaqyw
P----EKTETYGGVTVTLHQ-T-EVFADYVIRTFILFREE-RAVRRMVRQFNFTVWPDKGVPQYATAVLAFRRKVRAlnprDAGPVIVHCSAGVGRTGAY
| || | .|. | . . | |. .| . ||....| |||.||| . | . .| |..||||||.||||.
paaqgeklelksgivvenvsgskpmerdaeiqitllnltysgdqkmsvrhlqwtewpdrgvppckltslellsairg....skvpivvhcsagigrtgti
IVIDAMLEQAKINRTV-DIRNYLIALRKDRPHMVQTKEQYSFIHSAVLE
. |. .||. |. . . . . ||| .| . .|. || ||| .|.
vaieyilekiaenkpcppmpelvkalrdqrafsiqndvqylfihrvmln
|
|||||||||
subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 350-588 | 3.3e-100 | 329.2 | In-house | 1-239 (239) | alignment | ||
Range on Protein: 350-588
Range on HMM: 1-239/239.0
DAARKAANKKKNRYGNIVTYDHSRVVLERVNGDEDSDYINASFIHGFDGTPRSYIASQGPPPPTFEGFWRMVWEQNSQSIVMLTNLVELGKTKCHKYWPE
.||.| || |||| |||||||||||||... | |||||||... .||.|..|||.|| .. ||||.|.. ||||| |.| | |||.|||.
eaakkrvnkaknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpd
KTETYGGVTVTLHQTEVFADYVIRTFILFREERAVRRMVRQFNFTVWPDKGVPQYATAVLAFRRKVRALNPRDAGPVIVHCSAGVGRTGAYIVIDAMLEQ
| | . |||..|||||||.||||.. . .. | | |. ||||||||||||||||| .|||. . | | ..|||||||||||..|||||| |
stskycnlrvtlrktevfadyiirtfvmsqvgqteeryvyqyhftvwpdkgvpqyatavlglrrkitkdslpgarpwvihcsagvgrtgaflvidamlrq
AKINRTVDIRNYLIALRKDRPHMVQTKEQYSFIHSAVLE
|| ..|||| ||. |.|.|||||||| ||| ||| ||||
akkqktvdifnyvkairedrphmvqtseqyvfihlavle
|
|||||||||
0042113 | (Phosphotyrosine protein) phosphatases II | 350-589 | 7.3e-79 | 259.9 | In-house | 2-242 (245) | alignment | ||
Range on Protein: 350-589
Range on HMM: 2-242/245.0
DAARKAANKKKNRYGNIVTYDHSRVVLERVNGDEDSDYINASFIHGFDGTPRsYIASQGPPPPTFEGFWRMVWEQNSQSIVMLTNLVELGKTKCHKYWP-
. |.. .||.|||| .|. |||.||.| ..||.||||||||...|.. ||. .||.||| | |.| ||||.||.....|||||...|||. ||..|||
svallpenkdknrysdilpydhtrvklspdggdldsdyinasyvdgyritpk.fiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywpl
EKTETYGGVTVTLHQTEVFADYVIRTFILFREERAVRRMVRQFNFTVWPDKGVPQYATAVLAFRRKVRALNP-RDAGPVIVHCSAGVGRTGAYIVIDAML
. . |||..|||| .|...||..||. . .. |.|... .. ||| ||| . .| | . || . |||.|||||||||||..|... ||
gesltygdftvtllseehlddytvrtlevtnlgddesrevihyhylpwpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylml
EQAKINRTVDIRNYLIALRKDRPHMVQTKEQYSFIHSAVLEA
||.. ...|.. . . ||. ||..||| .|| |.. |.||
eqlekelgvsleeavkelrsqRpgavqtpsqyrflyeallel
|
|||||||||
subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 351-599 | 7.9e-119 | 390.4 | In-house | 3-245 (250) | alignment | ||
Range on Protein: 351-599
Range on HMM: 3-245/250.0
AARKAANKKKNRYGNIVTYDHSRVVLERVNGDEDSDYINASFIHGFDGTpRSYIASQGPPPPTFEGFWRMVWEQNSQSIVMLTNLVELGKTkCHKYWP-E
|.| .||.|||| .|...|.||||||...||..||||||||.||.|.. ...||.||| ..|.|.|||||.|..|..|||||||.| .|| .|.||| |
vakkpqnkeknryadiialdssrvvLekekgdkesdyinasflhgyder.kafiatqgPlqatiedfWrmvleeksgtivmLtnLkesekt.yhqywPve
KTETYGGVTVTLHQTEVFADYVIRTFILFREERAVRRMVRQFNFTVWPDKGVPQYATAVLAFRRKVRALNPR-DAGPVIVHCSAGVGRTGAYIVIDAMLE
|.|.||.|||.|...|.||||..|...| ....| .|.|||..|.||||||||..|||||....||.| ... ...||||.|||||||.||.|.|||.||
kaekyGdvtvsllskeefadytkrklklskakkaderivrqlhfvvWPdkgvPevatavLellkkvqasqqqagnaPvivqCsaGvgrsGafiaidavle
QAKINRTVDIRNYLIALRKDRPHMVQTKEQYSFIHSAVLEALTCgnteiqS
..|....||.......|||||||.|...|||.|.....|.||.. .
rlkkekvvdvfkvikvlrkdrphavesleqyvfvyeiilkalds......v
|
|||||||||
subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 351-589 | 1.7e-100 | 330.1 | In-house | 1-239 (239) | alignment | ||
Range on Protein: 351-589
Range on HMM: 1-239/239.0
AARKAANKKKNRYGNIVTYDHSRVVLERVNGDEDSDYINASFIHGFDGTPRSYIASQGPPPPTFEGFWRMVWEQNSQSIVMLTNLVELGKTKCHKYWPEK
||.| || |||| |||||||||||||... | |||||||... .||.|..|||.|| .. ||||.|.. ||||| |.| | |||.|||.
aakkrvnkaknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpds
TETYGGVTVTLHQTEVFADYVIRTFILFREERAVRRMVRQFNFTVWPDKGVPQYATAVLAFRRKVRALNPRDAGPVIVHCSAGVGRTGAYIVIDAMLEQA
| | . |||..|||||||.||||.. . .. | | |. ||||||||||||||||| .|||. . | | ..|||||||||||..|||||| ||
tskycnlrvtlrktevfadyiirtfvmsqvgqteeryvyqyhftvwpdkgvpqyatavlglrrkitkdslpgarpwvihcsagvgrtgaflvidamlrqa
KINRTVDIRNYLIALRKDRPHMVQTKEQYSFIHSAVLEA
| ..|||| ||. |.|.|||||||| ||| ||| |||||
kkqktvdifnyvkairedrphmvqtseqyvfihlavlea
|
|||||||||
subfamily_Sponge-PTP4_pd | Subfamily Sponge-PTP4 | 351-498 | 1e-10 | 35.7 | In-house | 90-232 (244) | alignment | ||
Range on Protein: 351-498
Range on HMM: 90-232/244.0
AARKAANKKKNRYGNIVTYDHSRVVLERvnGDEDSDYINASFIhGFDGTPRSYIASQGPPPPTFEGFWRMVWEQNSQSIVMLTNLVElgktkCHKYWPE-
| . | ||| | . .| .|| | . | ||||||. | | || .| | | ||.|. |. . .|.| . | .|||.
dafnpnnswknregaglpfdfnrvplsk..gsmgntyinasfv.gclgrtaeyiltqhpladtsmdfwkmmlerhvnvlvvlgsvee.....edeywpds
-KTETYG-GVTVTLHQTEVFADYVIRTFILFREERAVRRMVRQFNFTVWPD
| | .|||| . . | . . . . . . |. . ||
eplewyeeditvtltdrdefknikasnleiesdmneshqaltmfqisnwps
|
|||||||||
subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 352-610 | 3.1e-77 | 254.9 | In-house | 20-275 (284) | alignment | ||
Range on Protein: 352-610
Range on HMM: 20-275/284.0
ARKAANKKKNRYGNIVTYDHSRVVLERVNGDEDSDYINASFIHGFDgTPRSYIASQGPPPPTFEGFWRMVWEQNSQSIVMLTnlvelgKTKCHKYWPEKT
| || |||.|.|...|...| |||. | | ||||||||| |. . |||.||| . | . ||||.||.|. .||.|| | || .||| |.
anldqnkdknrighilafdknvvklerliGeefsdyinasfitGyq.rkdkyiatqGPldntladfWrmiweyncstivllt......kdkcsqywplki
-ETYGGVTVTLHQTEVFADYVIRTFILFR-EERAVRRMVRQFNFTVWPDKGVPQYATAVLAFRRKVRALNPRDAG--PVIVHCSAGVGRTGAYIVIDAML
.... | .. | ..||.| . | . . | .||| | |||.|||.|.. .... .||| |. . . ...|||||||||||.|||.|..|
vikeerfkvkvdsveeseeyvvrdielsedgkekdirkirqfhflgwpdvgvpdypsdlmrlvkkvrhltskenhranivvhcsagvgrtgvyivldvll
EQAKINRTVDIRNYLIALRKDRPHMVQTKEQYSFIHSAVLEALTCGNTEIQSENFNQTTQKLA
.. | .. ||. |.. ||..|...|| || ||.||.|| |.... .| ..|.
drmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysalleehlfghsdvalpdfpayleels
|
|||||||||
subfamily_Sponge-PTP6_pd | Subfamily Sponge-PTP6 | 352-604 | 1.2e-66 | 220.0 | In-house | 41-293 (439) | alignment | ||
Range on Protein: 352-604
Range on HMM: 41-293/439.0
AR--KAANKKKNRYGNIVTYDHSRVVLERVNGDEDSDYINASFIHGFDgTPRSYIASQGPPPPTFEGFWRMVWEQNSQSIVMLTNLVELGKtkchkYWPE
. . .. |||| .....||.||.|. . | | |||| .|.|. ... |||.||| | . |||.|.|... ||||||||| | |||
slaaqeydqtknrykdvgafdhtrvtlqeipgvphshyinanyikGyy.ddklyiatqgpkkettddfwrlviekktvtivmltnlvesyk.....ywps
KTETY-GGVTVTLHQTEVFADYVIRTFILFREE--RAVRRMVRQFNFTVWPDKGVPQYATAVLAFRRKVRALNP-RDAGPVIVHCSAGVGRTGAYIVIDA
..|.. | ..| . . .|||| | .| | | | || .. |||| || |. || | | . . | .. |||.|||||||||||. | .|
daevcygdiavrvdrnielpnyvirgfkvfnerdttekertvlqfhyiawpdknvpaqashvldflrainsandkeeygpvvvhcsagvGrtGtiialdi
MLEQAKINRTVDIRNYLIALRKDRPHMVQTKEQYSFIHSAVLEALTCGNTEIQSENFNQ
||| |.. |||. . |||.| .|||. || ||. |||| . |.. .. ..|..
aleqlklenkvdikgivkvlrkqrkqmvqalcqyvfiynavledivyGdiavtidefkk
|
|||||||||
subfamily_Cele-PTP-13_pd | Subfamily Cele-PTP-13 | 353-588 | 7.4e-36 | 118.2 | In-house | 33-267 (281) | alignment | ||
Range on Protein: 353-588
Range on HMM: 33-267/281.0
RKAANKKKNRYGNIVTYDHSRVVLER-VNGDEDSDYINASFIHGfDGTPRSYIASQGPPPPTFEGFWRMVWEQNSQSIVMLTNLVELGKTKCHKYWPEKT
. |.||||| || | ||| |. . . .||| | .|. | || .||| | ||||.|..|. .|||| ...| . || .|.| ..
nqpvnnkknrylnipcldisrvqlkvkmpnknstdyihanyirs.pflkrgyiltqgpkketradfwrmiwqenttaivmlcqfletnrekcaeyfprna
E---TYGGVTVTLHQTEVFADYVIRTFILFREERavRRMVRQFNFTVWPDKGVPQYATAVLAFRRKVRAlnpRDAgPVIVHCSAGVGRTGAYIVIDAMLE
. ..|. .. | | . | | |.. .. . ||| ||. . .| ||.|| | . | ..||||||||.|. . .. |.
hcclqfdklsvsyedstvnkslvttrlnlsyege..trlithwlwkewpdwqvpessevmlkilrkira...rst.ppvihcsagvgrsgtlmaveialq
QAKINRTV-DIRNYLIALRK-DRPHMVQTKEQYSFIHSAVLE
. |. ||.. . || | ||| .|| .| .|.
sihshftlpdikqivshlrvtgraasvqtlqqymliwkvlld
|
|||||||||
subfamily_ptpA1_pd | Subfamily ptpA1 | 353-548 | 9.9e-35 | 115.1 | In-house | 43-254 (418) | alignment | ||
Range on Protein: 353-548
Range on HMM: 43-254/418.0
RKAANKKKNRYGNIVTYDHSRVVLERVNGDEDSDYINASFIHGfdGTPRSYIASQGPPPPTFEGFWRMVWEQNSQSIVMLTNLVELGKTKCHKYWPEKTE
| | |||| ||. .|.|| |.... | |||||| .| | |. .|..||| | | |||||||. . ||||. | . || .||||.
dkkhntsknrytnilpvnhtrvqlkkiqdkegsdyinanyidg..aypkqfictqgplpntiadfwrmvwenrcriivmlsresencrikcdrywpeqig
TyGGVTVTLHQTEVFADYVIRTFILFR-EERA------------VRRMVRQFNFTVWPDKGVPQYATAVLAF-----RRKVRALNPRD-AGPVIVHCSAG
... ||| | . . . || | . |... |||. .|... . . |. . . | |.|||||||
g.eqfsiygngnevfgtysvelveviqdpereiitrnirltfegetrditqyqyegwpdhnipdhtqpfrqllhsitnrqnqiipssdrnvpiivhcsag
VGRTGAYIVIDAMLE
|||||.. |..
vgrtgtfctavimmk
|
|||||||||
subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 354-588 | 8.8e-42 | 137.7 | In-house | 53-281 (290) | alignment | ||
Range on Protein: 354-588
Range on HMM: 53-281/290.0
KAANKKKNRYGNIVTYDHSRVVLErvNGdEDSDYINASFIHGFDgtpRSYIASQGPPPPTFEGFWRMVWEQNSQSIVMLTNLVELGKTKCHKYWPEKT--
| .. ||||| ..| | .||.|. .| | ||. | ...| . .| .||. | .|||| ... |||| .|.| ||.||..|.|||
kntefkknrykdvvcndktrvilk..dG.ydGdyvhanyvkGlk...amfiltqGalkdtvidiwrmvlqekvaaivmlceliedGkakceqyypekeGe
-ETYGGVTVTLHQTEVF-ADYVIRTFILFREERAVRRMVRQFNFTVWPDKGVPQYATAVLAFRRKVRALnprdAGPVIVHCSAGVGRTGAYIVIDAMLEQ
|.| .||. . . |. . .|. . . ... .. |||| |.. . |.| | .| . .|||.||||||.||||... |.. |.
vltfGeitvlcseeddkdaniikktlsvrdkdsGkehklkhlkikswpdksvalstlallrtlrilrka....sGpvvvhcsaGiGrtGtfvaievglqi
AKINRTVDIRNYLIALRKDRPHMVQTKEQYSFIHSAVLE
. .|. . |||. | || || . ..|.
lldGkeldlldlvralrnsrlnsvqvdiqylalveilld
|
|||||||||
subfamily_Cele-PTP-16_pd | Subfamily Cele-PTP-16 | 354-589 | 1.3e-13 | 45.2 | In-house | 44-278 (303) | alignment | ||
Range on Protein: 354-589
Range on HMM: 44-278/303.0
KAANKKKNRYGNIVTYDHSRVVLervngdEDSDYINASFIHgFDGTpRSYIASQGPPPPTFEGFWRMVWEQNSQSIVMLTNLVELGKTKCHKYWPEKTET
| .|||. ... |||.| | || || ||... .| . . | .| | . | ||.|. ||. . ...| | | . .|.. .
fvknmdknrfvdvicldhskvkl......sdssyihasyle.ldss.kkailtqlplshtaadfwqmiieqkvkcvlllltdseydklggdsvfprnqdf
YG----GVT-VTLHQTEVFADYVIRTFILfrEERAVRRMVRQFNFTVWPDKGVPQY-----ATAVLAFRRKVRALnpRDAGPVIVHCSAGVGRTGAYIVI
. ... |. .|.. . . . .. . || . .| . . .| |. | . .|.||.|.. ..
lkfeersirvgefkrvelgdgwvlkvlsv..sngdyksflhvhhykawphnsipsdgspkfvkqiwqlqsvlrky..sdstptvymslsgcgragtfalf
D-AMLEQAKINRTVDIRNYLIALRKDRPHMVQTKEQYSFIHSAVLEA
. | | . . ..|. . | .|. | | || |.|.... . |
etahlslhseqasldlvkclenvrngrlhavqnlsqfsvvytllaeh
|
|||||||||
subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 355-588 | 6e-37 | 122.1 | In-house | 31-257 (267) | alignment | ||
Range on Protein: 355-588
Range on HMM: 31-257/267.0
AANKKKNRYGNIVTYDHSRVVLERVNGDedsdYINASFIHGFDgTPRSYIASQGPPPPTFEGFWRMVWEQNSQSIVMLTNlveLGKTKCHKYWPEK---T
|...||. . . ||..||.| . . |||||...|. | . .|. |.| | |. .. .|. ||.||. .. . ...|| | .
eknqernrlddnlpyddtrvilrtkeee....yinasyvegyk.tknafivtqdplkntitdfltvihdqkvpvivlltk...vftdnirlfwPPkmgqa
ETYGGVTVTLHQTEVFADYVIRTFIL-FREERAVRrmVRQFNFTVWPDK-GVPQYATAVLAFRRKVRALNprDAGPVIVHCSAGVGRTGAYIVIDAMLEQ
. | .|| . || | |. | |..| | | . . | . | ... | . | |..|.||.||||.|...|||..||.
kkyqdltvehslekeendyqiitlelkfknesahn..vtlyyykkwnintnnkpylkplfgilaknqlen..gnrPlvvacsdGvGrsGtflvidsqler
AKINRTVDIRNYLIALRKDRPHMVQTKEQYSFIHSAVLE
|| . ..|| ..| .|. |. .|.|||.| .|| . |
aktegvsdifdflrkirsqriglvdtkeryiyihellae
|
|||||||||
subfamily_Cele-PTP-15_pd | Subfamily Cele-PTP-15 | 355-590 | 1e-31 | 105.0 | In-house | 33-270 (285) | alignment | ||
Range on Protein: 355-590
Range on HMM: 33-270/285.0
AANKKKNRYGNIVTYDHSRVVLErvngDEDSDYINASFIHGFDGTPRSYIASQGPPPPTFEGFWRMVWEQNSQSIVMLTNLVELGKTKCHKYWPEKTE--
|| ||| .. . .||||. . | ||| ||... .||..||| | |. ||.|..... ..|| |.| | || |.|||
eanpdlnryadvrcieetrvvlk....nhdrdyihaswmrmpgkdqstyittqgplpetlsdfwhmiyqekiayvlmlctlfeggvekcalyypeklgev
-TYGGVTV--TLHQTEVFADYVIRTFILFREERAVRRM--VRQFNFTVWPDKGVPQYATAVLAFRRKVRALNPRDAgPVIVHCSAGVGRTGAYIVIDAML
.| . | . | | .. .. . | | . . . |||. |. | .. . . |. .||.. |. |||||||||| ... ||
vkfgkyeitlteckeeaiagtilnaltvintedasseplymnhvqvpwwpdqlapedarpmielykwvkkvnpkek.picvhcsagvgrtatfvgidyat
EQAKINRTVDIRNYLIALRKDRPHMVQTKEQYSFIHSAVLEAL
. | ... . . .| | . ||.. |. |.. ..| .
irimenpniemldivremramrfqavqshmqflflyvvlmeyf
|
|||||||||
subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 356-588 | 1e-89 | 294.9 | In-house | 2-237 (237) | alignment | ||
Range on Protein: 356-588
Range on HMM: 2-237/237.0
ANKKKNRYGNIVTYDHSRVVLERVNGDedSDYINASFIHGFDGTPRSYIASQGPPPPTFEGFWRMVWEQNSQSIVMLTNLVELGKTKCHKYWPE--KTET
|| ||||||||.||||||||. .. ||||||....||||||..|||.||| .. . ||.|||... ||||| |.| . |||||||. . ..
enkiknrygnivaydhsrvvlkgagsg..sdyinatylkgfdgtpkkyiaaqgplesscddfwqmvwqekcsvivmltgliegnelkchkywpstdqpaa
YGGVTVTLHQTEVFADYVIRTFILFREE-RAVRRMVRQFNFTVWPDKGVPQYATAVLAFRRKVRALNPR--DAGPVIVHCSAGVGRTGAYIVIDAMLEQA
|| .||.|.. | |.|| .|...|... |.. |..||.|||.||||...|.| ||... .| ..|| |.|||||||||| ..|||||| ||
ygvltvslkkkeefsdytvrslllskrltlkevrlihqyqftswpdrgvpqqtaallrfrkniinrsphvsesgpwiihcsagvgrtgiflvidamlrqa
KINRTVDIRNYLIALRKDRPHMVQTKEQYSFIHSAVLE
| .. ||| ||. .. .|||...|||.|| ||| ..||
kekkvvdiynyvysieedrpyiiqtkdqyvfihqtile
|
|||||||||
subfamily_Cele-PTP-17_pd | Subfamily Cele-PTP-17 | 356-431 | 1.2e-08 | 28.9 | In-house | 36-115 (347) | alignment | ||
Range on Protein: 356-431
Range on HMM: 36-115/347.0
ANKKKNRYGNIVTYDHSRVVLER-----VNGDEDSDYINASFIHgFDGTPRSYIASQGPPPPTFEGFWRMVWEQNSQSIVM
. .||| . | .|||| . |. ||||| |. || . . || .| | | | ||.|| . .|
kslsknrskdvklidatrvvlspeksknsraddvetyinashik.fdnaskeyiltqyplpdtvrdfwkmvsvtkvtqvvt
|
|||||||||
subfamily_Cele-PTP-12_pd | Subfamily Cele-PTP-12 | 356-440 | 1.1e-07 | 25.6 | In-house | 33-115 (332) | alignment | ||
Range on Protein: 356-440
Range on HMM: 33-115/332.0
ANKKKNRYGNIVTYDHSRVVLERVNGDedSDYINASFIHGFDGTpRSYIASQGPPPPTFE-GFWRMVWEQNSQSIVMLTNLVELGK
| || . .||||| | .| |. |||.. |. .|| .| | | ||||| |.. |... .. | |
nnmdmnriphlycfdhsrvelapqdgk..ddfynaswvdgyskk.sayifaqapfndhteyvfwrmvserkpsmilvfgdidekqk
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 357-588 | 8.2e-79 | 259.7 | Pfam-A | 1-235 (235) | alignment | ||
Range on Protein: 357-588
Range on HMM: 1-235/235.0
NKKKNRYGNIVTYDHSRVVLervNGDED-SDYINASFIHGFDgTPRSYIASQGPPPPTFEGFWRMVWEQNSQSIVMLTNLVELGKTKCHKYWP---EKTE
||||||| .|. ||..|| | .|.|. ||||||....|.. .....||.||| . |.| ||||||......|||||.|.| |..||..||| |...
nkkknRykdilpydktrvkl...kgsegpsdYInAnyvkgyk.ekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeesl
TYGGVTVTLH-QTE-VFADYVIRTFILFREERA-VRRMVRQFNFTVWPDKGVPQYATAVLAFRRKVRALNPRDAGPVIVHCSAGVGRTGAYIVIDAMLEQ
||| ..|.| ... ..|..|.. | ... .|.|.|. .| |||.|||. ....| . |||. . . |||.||||||||||| ....|..|||
tygdikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldilleq
AKINRTVDIRNYLIALRKDRPHMVQTKEQYSFIHSAVLE
.. ...||. ... ||| ||.|||. ||| |.. |.||
leaeeevdvlqivkelRkqRpgmvqsleqYiflykaile
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 357-588 | 8.2e-79 | 259.7 | In-house | 1-235 (235) | alignment | ||
Range on Protein: 357-588
Range on HMM: 1-235/235.0
NKKKNRYGNIVTYDHSRVVLervNGDED-SDYINASFIHGFDgTPRSYIASQGPPPPTFEGFWRMVWEQNSQSIVMLTNLVELGKTKCHKYWP---EKTE
||||||| .|. ||..|| | .|.|. ||||||....|.. .....||.||| . |.| ||||||......|||||.|.| |..||..||| |...
nkkknRykdilpydktrvkl...kgsegpsdYInAnyvkgyk.ekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeesl
TYGGVTVTLH-QTE-VFADYVIRTFILFREERA-VRRMVRQFNFTVWPDKGVPQYATAVLAFRRKVRALNPRDAGPVIVHCSAGVGRTGAYIVIDAMLEQ
||| ..|.| ... ..|..|.. | ... .|.|.|. .| |||.|||. ....| . |||. . . |||.||||||||||| ....|..|||
tygdikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldilleq
AKINRTVDIRNYLIALRKDRPHMVQTKEQYSFIHSAVLE
.. ...||. ... ||| ||.|||. ||| |.. |.||
leaeeevdvlqivkelRkqRpgmvqsleqYiflykaile
|
|||||||||
0041856 | (Phosphotyrosine protein) phosphatases II | 357-596 | 5.4e-49 | 161.6 | In-house | 1-177 (182) | alignment | ||
Range on Protein: 357-596
Range on HMM: 1-177/182.0
NKKKNRYGNIVTYDHSRvvlervngdeDSDYINASFIHGFDGTPRsYIASQGPPPPTFEGFWRMVWEQNSQSIVMLTnlvelgktkCHKYWPektetygg
|..|||| .|. ||||| |.|||||... | . | .|| |||.. |.. |.||..|.. ..||.|| .. |||
nldknrysdilpydhsr..........dldyInanlylgslpatr.fiatqgpllstvadflrmlkelgittivnlt.........eelywp........
vtvtlhqtevfaD-YvirtfilfreeravRRMVRQFNFTVWPDKGVPQyATAVLAFRRKVRAlnprDAGPVIVHCSAGVGRTGAYIVIDAMLEQakinrT
. . |.. |. .. ||| ||| .|.| ..|.. . |||.|||||||||||...... |...
............ell..............erlgiqylylpwpDhgvpd.ldelldfieevle....eggpvlVHCsaGvgRtgtlvaaylmkkl.....g
VDIRNYLIALRKDRPHMVQTKEQYSFIHSAVLEALTCGNTE
|.... . .|. ||.||.| .|| |.. |.|| | ...|.
vsleeavklvrsrRpgmvitpnqyfflqlallellllkktr
|
|||||||||
subfamily_Cele-PTP-19_pd | Subfamily Cele-PTP-19 | 357-582 | 3.1e-27 | 90.1 | In-house | 50-273 (301) | alignment | ||
Range on Protein: 357-582
Range on HMM: 50-273/301.0
NKKKNRYGNIvTYDHSRVVLERVNGDedSDYINASFIHGFdGTPRSYIASQGPPPPTFEGFWRMVWEQNSQSIVMLTNLVELGKTKCHKYWPEKTETY--
.|.|.|| .. . | | |.| | | .| | |. .||.||| . | | || |. . . ||||.. || ..||..| | |..
pkdkhryptv.PckPstavevivdGk..rvPihanwipts.GhphrfiatqgPlkntsedfwamlvqydvekivmlgqkvekleekceeylpvkisekld
-GGVTVTLHQTE-VFADYVIRTFILFRE--ERAVRRMVRQFNFTVWPDKGVPQYATAVLAFRRKVRalnpRDAGPVIVHCSAGVGRTGAYIVIDAMLEQA
| .......| .. . ... . .. .. | | .... |.|.|||. . . . |. . |..||||||.||. |.| . . .
igrfkikiknkelilnkkiskrtlevedstgkfatrtvthyqysewtdrgvPkshaelfdlmelvk....ksekPivvhcsaGiGrsvafigteylarev
KINRTVDIRNYLIALRKDRPHMVQTKEQYSFI
. ..|... . | ||..| . |||..| ..
eadptieltealkhlrehrwngvqtnsqlywm
|
|||||||||
subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 358-463 | 5e-22 | 73.1 | In-house | 48-164 (350) | alignment | ||
Range on Protein: 358-463
Range on HMM: 48-164/350.0
KKKNRYGNIVTYDHSRVVLER--------VNGDEDSDYINASFIHGF----DGTPRS-YIASQGPPPPTFEGFWRMVWEQNSQSIVMLTNLVELGKTKCH
|||| ||. |.|||| |.. . .|||||.... . | ||| |.| | |.. |.... . . . |..||..|||. ||.
faknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvelnlekcy
KYWPEKteTYGGVTVTLHQ
.||.| .| ..|| | .
rYWqeg..sydditvklas
|
|||||||||
subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 358-465 | 2.4e-13 | 44.2 | In-house | 49-169 (349) | alignment | ||
Range on Protein: 358-465
Range on HMM: 49-169/349.0
KKKNRYGNIVTYDHSRVVLERVN--------------GDEDSDYINASFIHGFDGTP-RSYIASQGPPPPTFEGFWRMVWEQNSQSIVMLTNLVELGKTK
|||| .|. |.||||.|.. . ||||| ... .. . ||| | | | | . |.... .. . .. |.. ||. |
faknrykdilPyehsrvklkkslksskvikastsesdsgklddyinanylkltrisvekkyiatqaPlPstvddfykvillngvklvlsLnddkelslek
CHKYWPEKteTYGGVTVTLHQTE
|..|| | .| ..|| | .
cdiywqel..sysnitvklqnss
|
|||||||||
subfamily_Cele-PTP-1_pd | Subfamily Cele-PTP-1 | 359-602 | 5.4e-18 | 60.1 | In-house | 21-272 (290) | alignment | ||
Range on Protein: 359-602
Range on HMM: 21-272/290.0
KKNRYGNiVTYDHSRVVLERVNGDEDSDYINASFIHGFDGTprSYIASQGPPPP-------TFEGFWRMVWEQNSQSIVMLTNLVELGKT----KCHKYW
...|. . ..||||. .||| |... .| |..| | | | || |. . .....||| . | . | ||
mdqRlev.pLveatrvvLkgygkrfnddyiHAnrvtcpngl..rliltqsPqekitekrnStiekfwwmakqEkvkqvVmlcefeeksantslfaCakYv
PEKTE---TYGGVTVTLHQTEVFADYVIRTFILfREERAVRRMVRQFNFTVWPDKGVPQYATAVLAFRRKVRalnpRDAGPVIVHCSAGVGRTGAYIVID
||. . ...|.|| . | | .|. .. . . . | . | . |.. .|. .||. |||||| |. | | |.
pesvgeelkfkgltvkCkskekeddvetRelvv.kfddeeeftvtHsllkgWnklnvqedtktllsliqkvk....asktpvivHcvdGiSrsAalaaii
AML-EQAKINRTVDIRNYLIALRKDRPHMVQTKEQYSFIHSAVL-EALTCGNTEIQSENF
|. . | ... | |||| | ..........|. ... | ... ...|.
lgyQkiaetsgsvkledvlkalrkqralaitsalelafvdagivllaievldqfaeeete
|
|||||||||
0044763 | (Phosphotyrosine protein) phosphatases II | 369-587 | 4.7e-37 | 122.7 | In-house | 2-168 (178) | alignment | ||
Range on Protein: 369-587
Range on HMM: 2-168/178.0
YDHSRVVLERVNGDEDSDYINASFIHGFdgtprSYIASQGPppptfEGFWRMVWEQNSQSIVMLTNLVELGKTKCHKYWPEKTEtyggvtvtlhqtevfa
.|..||.|. . | | |||||||.| .. |..|..| . ......|.. ..||.||. .|||. ||..||||...
ldrtrvllsnleglersdyinaseilpg.....lylgslpp.....addlellkelgithivnlteelelgflkcdpywpeeag................
dyvirtfilfreeravrrmvRQFNFTVWPDKGVPQYATAVLAFRRKVRALNPRDAGPVIVHCSAGVGRTGAYIVIDAMLEQakinrTVDIRNYLIALRKD
|. .. .|| |||. .|.| . .... ... |||.|||||||||.|. .... |... ... . . .|.
....................iqylhipipDhgvpdllehflefvefieealdekggpvlVHCsaGvgRsgtlvaaylmkkl.....glsleeaielvrer
RPhMVQTKEQYSFIHSAVL
|| .|.. .|. ... |
Rp.ivpnpgqlrqLyefel
|
|||||||||
subfamily_Sponge-PTP-4_pd | Subfamily Sponge-PTP-4 | 369-500 | 5.5e-06 | 20.7 | In-house | 5-125 (130) | alignment | ||
Range on Protein: 369-500
Range on HMM: 5-125/130.0
YDHSRVVlervngdeDSDYINASFIhGFDGTPRSYIASQGPPPPTFEGFWRMVWEQNSQSIVMLTNLVElgktkCHKYWPEKT--ETY-GGVTVTLHQTE
.. ||. . .||||||. | | . |. .| | | ||.|. |. .|.| . | .|||. | | ..||| . .
fevsrlq........gntyinasfv.Gllgrtaeylltqhpladtsmdfwkmmleryvnvlvvlgsvee.....edeywpdsePlewyeediivtltdrd
VFaDYVIRTFIlFREERAV--RRMVRQFNFTVWPDKG
| ... ... |. . . . |. . || |
ef.knikasnl.eiesdlneshqaltmfqisnwpsdg
|
|||||||||
0046846 | (Phosphotyrosine protein) phosphatases II | 379-588 | 4.2e-41 | 135.9 | In-house | 6-171 (176) | alignment | ||
Range on Protein: 379-588
Range on HMM: 6-171/176.0
VNGDEDSDYINASFIHGFDgtprsYIASQGPPPPTFEGFWRMVWEQNSQSIVMLTNLVELGKTKCHKYWPEKTETYGgvtvtlhqtevfadyvirtfilf
|.|.|||||..| | .|| ||| | |.. |..|..|.. . .|.||..||||. ||. |||| ..
lgldldldyinanlilgsr.....piatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpeleklgi.......................
reeravrrmvrQFNFTVWPDKGVPQYaTAVLAFRRKVRALNPRDaGPVIVHCSAGVGRTGAYIVIDAMLEqakiNRTVDIRNYLIALRKDRP-HMVQTKE
|. .. ||| |||.. ...| . . .| .. |||.||||||.||||...... . .. ... . | .|. || ..||| |
...........qylhlpwpDhgvpdl.elllellefirealkeg.gpvlVHCsaGigRtgtlvaayllel....ekglsveealalvreqRplgavqtpe
QYSFIHSAVLE
|| |.. ..|.
Qyrflyefell
|
|||||||||
0043147 | (Phosphotyrosine protein) phosphatases II | 381-583 | 1.7e-39 | 130.6 | In-house | 1-154 (172) | alignment | ||
Range on Protein: 381-583
Range on HMM: 1-154/172.0
GDEDSDYINASFIHGFDGTPRsYIASQGPPPPTFEGFWRMVWEQNSQSIVMLTNLvelgktkchkywpektetyggvtvtlhqtevfadyvirtfilFRE
|||.|||||||.... ..| .|| ||| . |.. ||||..|.. . ||.||.| .
gdegsdyinasyldlyyipdr.fiatqgplrntladfwrmlkelgithivnltel..........................................lyd
ERAVRRMVRQFNFTVWPDKGVPqYATAVLAFRRKVRA-LNPRDAGPVIVHCSAGVGRTGAYIVIDAMLeqakinRTVDIRNYLIALRKDRPHMVQTKEQY
. |.. |. .. ||| ||| . .| | . .. |. .. |||.|||||||||||. .... || . ... . . .|. ||..||...||
pellerlgiqylylpwpDhgvp.llellleflefidellalspggpvlVHCsaGvgRtgtlvaaylml......lglsleeavalvrekRpgavqnpsqy
SFIH
|..
rfly
|
|||||||||
0051082 | (Phosphotyrosine protein) phosphatases II | 384-587 | 2e-33 | 110.4 | In-house | 2-150 (151) | alignment | ||
Range on Protein: 384-587
Range on HMM: 2-150/151.0
DSDYINASFIHGFdgtprsYIASQGPppptFEGFWRMVWEQNSQSIVMLTNLVELGktKCHKYWPEKTetyggvtvtlhqtevfadyvirtfilfreera
|||||.|.. |. ...|.|| . |.....|.. ..||.|....| | .|..|.||
lsdyinfsyvtgg......lyrsggp....ladflellkelgiktivnlrseeerg..ycpeylpelg................................
vrRMVRQFNFTVWPDKGVPQYATAVLAFRRKVRAlnpRDAGPVIVHCSAGVGRTGAYIVIDAMLEQakinrtVDIRNYLIALRKDRPHMVQTKEQYSFIH
. |... .. ||| |.|.. |||.| ..... . |||.||||||.||||. .... ||.. |.. | .|. ||..||...|. |..
..ievlhipildwpdpglplsfdavleflellld...kkngpvlvHCsaGkgRTGtlvalylmllg......vsleealeeyrlkrpgvvqpnqqflfql
SAVL
|.|
fall
|
|||||||||
0051429 | (Phosphotyrosine protein) phosphatases II | 385-592 | 5.7e-52 | 172.3 | In-house | 4-226 (272) | alignment | ||
Range on Protein: 385-592
Range on HMM: 4-226/272.0
SDYINASFIHGFdGT---PRSYIASQGPPPPTFEGFWRMvWEQNSQSIVMLTNLVELGKTKCHKYWP-------------EKTETYGGVTVTLHQTEVFA
|.||||... |. | |. ...|.|| | | ..|||. .|.. .||.|....|.|. ||..||| . | .|| ..|||...|..
sgyiNardvggy.grvvkpgrlyrsggplpltaadfwrl.kelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseelll
DYVIRTFILFRE-ERAVRRMVRQFNFTVWPDKGVPQYAtaVLAFRRKVRAlnprdAGPVIVHCSAGVGRTGAYIVIDAMLEQAKINRTVD--------IR
||..|...| .. |.|... .| ||| |||| | .|.. . ... |||.||||||..||| ..... .|.. . || ..
dyilrellltlllsagearevmhlhytdwpdhgvpqea..llellellld.....ggpvlvHCsaGkdRTGtvvallllllgvsletivddYlltnlyle
NYLIALRKDRPHMVQTKEQYSFIHSAVLEAlTC
... ||. ||..||| ||| |.. |.||. .
eaveelraqrpgavqteeqylflyeallel.lr
|
|||||||||
0036282 | (Phosphotyrosine protein) phosphatases II | 385-583 | 2.1e-44 | 146.6 | In-house | 2-163 (174) | alignment | ||
Range on Protein: 385-583
Range on HMM: 2-163/174.0
SDYINASFIHGFDGTPrSYIASQGPPPptfegFWRMVWEQNSQSIVMLTNLVELGKTKCHKYWPEktetyggvtvtlhqtevfadyvirtfilfrEERAV
|||||||..... || .||.||| . ||.|..|......|||....|||..||. ||||
sdyinaspldlsyitp.rliagqgpla.....fwemlkelgittvvmlleekelglykcinywpe..............................lredl
RRMVRQFNFTVWPDKGVPQYATaVLAFRRKVRALNPR-DAGPVIVHCSAGVGRTGAYIVIDAMLEQAKiNRTVDIRNYLIALRKDRPHMVQTKEQYSFIH
.|.. |. .. ||| ||| .. .| | . |. . . |||.|||||||||||. .... || . . ...||. ... .||. ||.|||| .|| |..
erlgiqylylpwpDhgvpdlsi.llefvkfveealsedpggpvlVHCsaGvgRtGtlvaaylmlrgll.eslvdaldlvrelRlqrpgmvqtpsQyrfly
|
|||||||||
subfamily_Cele-PTP-7_pd | Subfamily Cele-PTP-7 | 397-590 | 4e-17 | 56.6 | In-house | 84-288 (302) | alignment | ||
Range on Protein: 397-590
Range on HMM: 84-288/302.0
DGTPRSYIASQG---PPPPTFEGFWRMVWEQNSQSIVMLTNLVELGKTKCHKYWPEKTE---TYGGVTVTLHQ----TEVFADYviRTFILF-------R
||| . |. | | | .| .. . | .| |...|| .. || .|. .| . ..| ||. . | |.| ..| |. .
dGtekkekvskkpivpkkstlekhwalieqynvaivvqlcsfvedeekkcaeyysdkvggelkfgrytvktvsvktdleeftdk..ksfklytveiknek
EERAVRRMVRQFNFTVWPDKGVPQYATAVLAFRRKVRALNPRdagpVIVHCSAGVGRTGAYIVIDAMLEQAKINRTVDIRNYLIALRKDRPHMVQTKEQY
...|.. | . |. |||.| |. | . | . . |.|||||||||||. . | .. . ... |. . .. .|. | ||...|
kkkkvkktvdilafsawpdhGapkeaytaldilkfcesykkn....vlvhcsaGvGrtGtlvaikyGiqlcskkkvtdllsivlpvrqcryGavqdeqql
SFIHSAVLEAL
.. | .|
iylllcvtkgl
|
|||||||||
0049260 | (Phosphotyrosine protein) phosphatases II | 399-583 | 1.5e-38 | 127.2 | In-house | 7-143 (152) | alignment | ||
Range on Protein: 399-583
Range on HMM: 7-143/152.0
TPRSYIASQGPPPPTFEGFWRMVWEQNSQSIVMLTNLVELGKTKCHKYWpektetyggvtvtlhqtevfadyvirtfilfreeravrrmvrQFNFTVWPD
|. .|| ||| | |.. ||||..|.. . |||||.|.|||| ||..|. |. .. |||
mpfefiatqgpgpntladfwrmlkelgittivmltellelgklkceqyi..........................................qylhlpwpD
KGVPQYATAVLAFRRKVRALNPRDAGPVIVHCSAGVGRTGAYIVIDAMLeqakinRTVDIRNYLIALRKDRPHMVQTKEQYSFIH
|||. . .| . . .. |. .. |||.|||||||||||...... || . |.. ... .|. ||..|....|. |..
hgvpdlsqlllflllfieklaldkggpvlVHCsaGvgRtgtlvaaylml......lgvsleeavalvrekRpgavpnpgqlrfly
|
|||||||||
subfamily_Anemone-PTP-3_pd | Subfamily Anemone-PTP-3 | 401-583 | 3.3e-22 | 73.6 | In-house | 5-197 (199) | alignment | ||
Range on Protein: 401-583
Range on HMM: 5-197/199.0
RSYIASQGPPPPTFEGFWRMVWEQNSQSIVMLTNLVELGKTKCHKYWPE---KTETYGGVTVTLHQTEVFADYVIRTFILFREERA--VRRMVRQFNFTV
| |||.| | |. ||.|||| | |||. . .. ||| | || ..|| . . .||.| ..|| . | | . ...||
rryiatqhplretmadfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyqfts
WPDKGVPQYAT---AVLAFRRKVRALNPRDAGPVIVHCSAGVGRTGAYIVIDAMLEQAKINRT--VDIRNYLIALRKDRPHMVQTKEQYSFIH
| .| |. | |.| | . . ||||||| | | || .. .| . . .| ||. . ||. | .. . ..| ||.
wkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiisslqhynfiy
|
|||||||||
subfamily_Nvec-PTP-3_pd | Subfamily Nvec-PTP-3 | 401-583 | 3.5e-22 | 73.5 | In-house | 4-196 (198) | alignment | ||
Range on Protein: 401-583
Range on HMM: 4-196/198.0
RSYIASQGPPPPTFEGFWRMVWEQNSQSIVMLTNLVELGKTKCHKYWPE---KTETYGGVTVTLHQTEVFADYVIRTFILFREERA--VRRMVRQFNFTV
| |||.| | |. ||.|||| | |||. . .. ||| | || ..|| . . .||.| ..|| . | | . ...||
rryiatqhplretladfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyqfts
WPDKGVPQYAT---AVLAFRRKVRALNPRDAGPVIVHCSAGVGRTGAYIVIDAMLEQAKINRT--VDIRNYLIALRKDRPHMVQTKEQYSFIH
| .| |. | |.| | . . ||||||| | | || .. .| . . .| ||. . ||. | .. . ..| ||.
wkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiisslqhynfiy
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 402-478 | 2.6e-06 | 21.0 | In-house | 237-312 (440) | alignment | ||
Range on Protein: 402-478
Range on HMM: 237-312/440.0
SYIASQGPPPPTFEGFWRMVWEQNSQSIVMLTNLVElgkTKCHKYWPEKTE--TYGGVTVTLHQTEVFADYVIRTFILF
..||.| | | |||.| . . .|.|| .| . | ||| .| |.| || . .| . .||. |
afiatqmpldstvldfwrlvhdyristiimlnqlnd...ktcsiywpvntrsvtfgpftvghkgsenmnrvkvrtlelk
|
|||||||||
subfamily_Cele-PTP-9_pd | Subfamily Cele-PTP-9 | 413-590 | 3.8e-21 | 70.3 | In-house | 40-221 (255) | alignment | ||
Range on Protein: 413-590
Range on HMM: 40-221/255.0
TFEGFWRMVWEQNSQSIVMLTNLVELGKTKCHKYWP-EKTETYGGVTVTLHQTEVFADYVIRTFILFRE--ERAVRRMVRQFNFTVWPDKGVPQYATAVL
| . |.... .... .|||... | |. ||..|.| || | |.. |. || |.|| . . |. . |. .... |..| |. | .|
tvdkfyqtivqtktevvvmlcdfaeegvekcssyfplekdeklkladvnvtttkssadvvlrtleitstlgekkkthtvkhysykGWieknaPelareil
AFRRKVRalnprDAGPVIVHCSAGVGRTGAYIVIDAMLE----QAKINRTVDI--RNYLIALRKDRPHMVQTKEQYSFIHSAVLEAL
. || |. .|.||||.|.||. |..... . . . ||.. .. | ||. |. ..| | .| ||. .
nilkvvr.....dsksvvvhCstGiGrsaafvlaelvyqkmirsldttetveldylslleelrskrkraihtPlqlafsilmvldlv
|
|||||||||
subfamily_hpo-7_pd | Subfamily hpo-7 | 414-608 | 5e-19 | 63.2 | In-house | 47-245 (263) | alignment | ||
Range on Protein: 414-608
Range on HMM: 47-245/263.0
FEGFWRMVWEQNSQSIVMLTNLVELGKTKCHKYWP-EKTETYGGVTVTLHQTEVFADYVIRTFILFR--EERAVRRMVRQFNFTVWPDKGVPQYATAVLA
. |.... .... .|||.. | |. || .|.| || | |.. |.| | ...| | .|. . |... .. |..| |. | .|
idkfyqtivqtktevvvmLcDfneegvekcssyfPlekdekqklanvnvcttkvqsdvllktlellstlgeKkkthtvkhysykgWiekndpelareiln
FRRKVRalnprDAGPVIVHCSAGVGRTGAYIVIDAMLE----QAKINRTVDI--RNYLIALRKDRPHMVQTKEQYSFIHSAVLEALTCGNTEIQSENFNQ
. .| . ...||||.|.||. |. |.. . . . ||.. .. | ||. |. ..| | .| ||. . ... . | |
ilkvar.....nskslvvhcstGiGrsaafsvaElvyqkmirsldttstveldylsLleelrssrkraihtPmqLafsilmvLdfvlnnfakgeleakyq
TTQK
.|
eirk
|
|||||||||
subfamily_Cele-PTP-12_pd | Subfamily Cele-PTP-12 | 437-583 | 4e-06 | 20.5 | In-house | 144-295 (332) | alignment | ||
Range on Protein: 437-583
Range on HMM: 144-295/332.0
ELGKTKCHKYWPEKTETYGGVTVTLHQTEVFADYVIRTFILFREERAVRRMVRQFNFTVWPDK-GVPQYATAVLAFRR--KVRALN--PRDAGPVIVHCS
|| |.|.||||. ..... .. ... ..|| | |. . . | | | .|.| . | . .|. . ||... |.
elkakicrkfwpekrskkdfpalsiqasddhsethmktfnltvtekkqdhqtvlmhfyewadasklpeymldmrasiklqyirsskktgvcigpimlvca
AGVGRTGAYIVIDAMLEQAKINRTVDIRNYLIALRKDRPHMVQTKEQYSFIH
.|| . . || .. . .. | ... . |.. .| ..| ||
tgvekcaisatidiivsriteehrvgfketmsaikmqrfgcfrtvgpystac
|
|||||||||
0048076 | (Phosphotyrosine protein) phosphatases II | 455-587 | 1.3e-24 | 81.9 | In-house | 14-140 (145) | alignment | ||
Range on Protein: 455-587
Range on HMM: 14-140/145.0
GGVTvTLHQTEVFADYVIRT-FILFREERAVRRMVRQFNFTVWPDKGVPQYATAVLAFRRKVRALNPRDaGPVIVHCSAGVGRTGAYIVIDAMLEqakin
|... | .. | ..|. |.| . | .|.. . |.. |. .. ||| |||. . .|.| . .... ... |||.|||||||||||...... ||.
gslp.taldlellkdlgittvlnltselellerlgiqylylpwpDhgvpdllellleflefieealkeg.gpvlVHCsaGvgRtgtlvaaylmll.....
RTVDIRNYLIALRKDRPHMVQTKEQYSFIHSAVL
. |.. . | .|. ||..|.. .|. |.. ..|
lgvsleealelvrsqrpgavpnpgqlrflyefel
|
|||||||||
0048179 | (Phosphotyrosine protein) phosphatases II | 467-584 | 6.6e-23 | 76.5 | In-house | 25-139 (144) | alignment | ||
Range on Protein: 467-584
Range on HMM: 25-139/144.0
FADYVIRTFILFREE---RAVRRMVRQFNFTVWPDKGVPQYATAVLAFRRKVRALNPRDaGPVIVHCSAGVGRTGAYIVIDAMLeqakiNRTVDIRNYLI
.... |.| | ..|| . |.. |. .. ||| |||.... .|.| . .... ... |||.|||||||||||...... |. . ... . |
lkklgittvinlteeyepefleregiqylhlpwpDhgvpdllellleflefieealeeg.gpvlVHCsaGvgRtgtlvaaylmk.....klglsleeala
ALRKDRPHMVQTKEQYSFIHS
.|. ||..|.. .|. |..
lvrsrrpgavpnpgqlrfLle
|
|||||||||
subfamily_PTPDC1_pd | Subfamily PTPDC1 | 481-583 | 3.7e-08 | 28.0 | In-house | 76-169 (182) | alignment | ||
Range on Protein: 481-583
Range on HMM: 76-169/182.0
ERAVRRMVRQFNFTvWPDKGVPQYATAvLAFRrKVRALNPrDAGPVIVHCSAGVGRTGAYIVIDAMLeQAkinrTVDIRNYLIALRKDRPHMVQTKEQYS
| ... . .||. |.| ||. .. | || | . | | ||| || |||| | . . .. . . .|. ||. .||.||
ealmeqgiyvynfg.wkDygvasleri.Ldiv.kvvafal.qegkvavhChaGlGrtGvliacylvy.ak....rltaekaiklvrskrpksiqtreqve
FIH
...
lvk
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 485-625 | 4.4e-31 | 102.7 | In-house | 88-229 (440) | alignment | ||
Range on Protein: 485-625
Range on HMM: 88-229/440.0
RRMVRQFNFTVWPDKGVPQYATAVLAFRRKVRALN-PRDAGPVIVHCSAGVGRTGAYIVIDAMLEQAKINRTVDIRNYLIALRKDRPHMVQTKEQYSFIH
| ..|... |||||||..| || . . | . ||..||||||.|||| |..|..| .|| . .|| ... ..|..||.|||| |||.|.|
srtlkqyhyqgwpdkgvpkfagpvlkmiqdvnesqekagngpllvhcsagagrtgviiavdsilreakrsdqidifsfinsmrnnrpqmvqtpeqyafvh
SAVLEALTCGNTEIQSENFNQTTQKLASVNRKFQMTGYALEF
||||.| ||.| | .. . ... | . . . ||
eavlegllcgdtliledditerveqiqwpnphtdksplqqef
|
|||||||||
PTPc_DSPc_SM00012 | 488-588 | 4.7e-31 | 102.5 | In-house | 2-105 (105) | alignment | |||
Range on Protein: 488-588
Range on HMM: 2-105/105.0
VRQFNFTVWPDKGVPQYATAVLAFRRKVRALNPRDA--GPVIVHCSAGVGRTGAYIVIDAMLEQAKIN-RTVDIRNYLIALRKDRPHMVQTKEQYSFIHS
|... .| |||.|||......| . |.|. . . .||.||||||||||| ....| .|.| . . ..||| ... .||| ||.||||.|||.|..
vkhyhytgwpdhgvPeesdsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgmvqteeqylflyr
AVLE
|.||
alle
|
|||||||||
0038934 | (Phosphotyrosine protein) phosphatases II | 495-583 | 8.2e-07 | 24.4 | In-house | 86-170 (194) | alignment | ||
Range on Protein: 495-583
Range on HMM: 86-170/194.0
VWPDKG-VPQYATAVLAFRRKVRALNPRDAGPVIVHCSAGVGRTGAYIViDAMLEQakinRTVDIRNYLIALRKDRPHMVQTKEQYSFIH
.||.| ||.... .. . || | | ||| ||.|||| .. .... . . . . .| ||..... .... ..
pfpddgtvPsleillrfldlvdeflnedpggvvaVHCkaGlgRtGtlva.aYLiyr....lgmsaeeAialfrekRpgaipnqdyleall
|
|||||||||
subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 514-590 | 2.5e-16 | 54.4 | In-house | 220-295 (297) | alignment | ||
Range on Protein: 514-590
Range on HMM: 220-295/297.0
KVRALNPRDAgPVIVHCSAGVGRTGAYIVIDAMLEQAKINRTVDIRNYLIALRKDRPHMVQTKEQYSFIHSAVLEAL
.|| ||.| ...|||||||||.| . |..|.. . .| |.. | ||. |. .||| ||. ....|||. |
slraemprna.yllvhcsaGvGrsGvvvlsdvilaklrkkripdvaailsilreqrarlvqtleqfellydavlkkl
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 521-585 | 2.5e-16 | 54.2 | In-house | 245-310 (319) | alignment | ||
Range on Protein: 521-585
Range on HMM: 245-310/319.0
RDAGPVIVHCSAGVGRTGAYIVIDAMLEQAKIN-RTVDIRNYLIALRKDRPHMVQTKEQYSFIHSA
. ||..|||| |||||| | | ... . . |.||| . . .|.|| . |.||||| ||.
esqGPlvvhcsdGvGrtGlviasdiairsleeskrsvdiPqlvssvrrdrasavltkeqyefiykv
|
|||||||||
subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 522-587 | 1e-12 | 42.5 | In-house | 261-341 (350) | alignment | ||
Range on Protein: 522-587
Range on HMM: 261-341/350.0
DAGPVIVHCSAGVGRTGAYIVIDAMLE-----------QAKI---NRTVDI-RNYLIALRKDRPHMVQTKEQYSFIHSAVL
. |..||||||||||| .. .| .|. |. ..| |. . ||| | |||...|. ||. |.|
rsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaaktrDlisiivnelrkqrismvqnldqfifiYeall
|
|||||||||
subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 522-588 | 2.8e-08 | 27.5 | In-house | 264-342 (349) | alignment | ||
Range on Protein: 522-588
Range on HMM: 264-342/349.0
DAGPVIVHCSAGVGRTGAYIVIDAMLE--------QAKI---NRTVDIRNYLI-ALRKDRPHMVQTKEQYSFIHSAVLE
. ...|||||| |||| .. .| .|. || . . |. . . ||| | ||| |. .|. |.|.
qlstllvhcsaGcGrtGvlvtldlllsileplqnesnkiklqallkDlisiivnelrkqrismvqnlaqfiaiyealLk
|
|||||||||
subfamily_eak_pd | Subfamily eak | 523-598 | 2.8e-10 | 34.1 | In-house | 237-313 (332) | alignment | ||
Range on Protein: 523-598
Range on HMM: 237-313/332.0
AGPvIVHCSAGVGRTGAYIVIDAMLE--QAKINRTVDIRNYLIALRKDRPHMVQTKEQYSFIHSAVLEALTCGNTEIQ
| |. .. | |.|...||| ... ..|.. . . .... .. | | | .. |.|||. .||. | | ...
fap.iiqsarGsaraGvfvvidllirlidnkkknlysvedlilkvkskrihsvlvalqhsfiyeivldyllrrnnrlr
|
|||||||||
subfamily_Sponge-PTP-7_pd | Subfamily Sponge-PTP-7 | 527-593 | 1.4e-16 | 54.6 | In-house | 2-68 (69) | alignment | ||
Range on Protein: 527-593
Range on HMM: 2-68/69.0
IVHCSAGVGRTGAYIVIDAMLEQAKINRTVDIRNYLIALRKDRPHMVQTKEQYSFIHSAVLEALTCG
.||||.| ||||..| | . . | .. ||| | . .|| || || . .| ||| |. ||| |
vvhcssgtgrtgtfiaimvemarikseklvdifnnvqymrkcrpmmvmneieyifihdalvealklG
|
|||||||||
subfamily_Sponge-PTP7_pd | Subfamily Sponge-PTP7 | 527-593 | 2e-16 | 54.1 | In-house | 1-67 (69) | alignment | ||
Range on Protein: 527-593
Range on HMM: 1-67/69.0
IVHCSAGVGRTGAYIVIDAMLEQAKINRTVDIRNYLIALRKDRPHMVQTKEQYSFIHSAVLEALTCG
.||||.| ||||..| | . . | .. ||| | . .|| || || ...| ||| |. ||| |
vvhcssGtGrtGtfiaimvemarikseklvdifnnvqymrkcrpmmvmneneymfihdalvealklG
|
|||||||||
subfamily_Sponge-PTP4_pd | Subfamily Sponge-PTP4 | 583-769 | 6.7e-14 | 46.1 | In-house | 32-212 (244) | alignment | ||
Range on Protein: 583-769
Range on HMM: 32-212/244.0
HSAVLEALTCGNTEIQSENFNQTTQKLASVNRKFQMTGYAlEFQRLNSFTSREIPAEEKSVgEEPQNLQKNRFCDIVALNSCRVMLRKEHAdeESDYINA
.||| | .. | |. |..| |.| ... | .. . . | |. | . .|.| ||| . .. || | | ||||
tnavlsanatknryinilpfdetrvilssskkegsdyina.nyiqgsqniirpdpsvmkda.fnpnnswknregaglpfdfnrvplskgsm..gntyina
VFLHAHRERNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHELDqeypQYWPDHGATKY--GHIGVSVLSKQEKGDVISTKLEVT
|. .| ||||| .| |||.|. . . .|.| . | | .|||| .. | |.. ..| .. ...||.
sfvgclgrtaeyiltqhpladtsmdfwkmmlerhvnvlvvlgsveeed....eywpdseplewyeeditvtltdrdefknikasnleie
|
|||||||||
0050432 | (Phosphotyrosine protein) phosphatases II | 585-889 | 5e-85 | 280.8 | In-house | 7-305 (308) | alignment | ||
Range on Protein: 585-889
Range on HMM: 7-305/308.0
AVLEALTCGNTEIQSENFNQTTQKLAS-VNRKFQMTGYALEFQRLNSFTSreipAEEKSVGEEPQNLQKNRFCDIVALNSCRVMLrkehaDEESDYINAV
|.||.|....|.|. ...... ..|. .......... ||..|.|.. .| ||.. |.| |||. ||... ..|| | ||.||||||
allelllfrdtsilvsslklsvldllkllekaldlglleeefeellsvkp....lleysvallpenkdkNrykdilpydhsRVkl.....degsdYInAs
FLHAH--RERNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHELD-QEYPQYWPDH---GATKYGHIGVSVLSKQEKGDVISTKLEVTRKKVRrKT
. . . . ...|||||.|| .||||||||| .... .||||..|.| . . ..||||. | ..||.. | .|| ....|.. ..||.| .. ..
yvdgyssklprkfIatqgPlpntvedFwrmvweqnvrvIvmLtklvengrekcaqYwplelgggsleygkftvtllseevlddytvrtleltnlgdg.es
HEVRHLHHVSWPDKCIPEVACSVLDLLDDVQTSQqqcGNAPVLVQCSNGVGRSGTFCVISSVIERLKTEQVIDVFQVIKRIRVNRPGAVESLTQYVFCYQ
..|.|.|. .||| ..|. . ..||.|. |..|. .. |..| ||.||||.|||... ..|.|..|. .|||...|..| |||.|... ||.|.|.
rtvthfhytnWpdhgvPpspeilldflelvrksl...pggpivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkklReqRpgmvqtpeqylflyr
IIQKYLGSFSDY
....|| .. .
alleylklkltk
|
|||||||||
subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 593-890 | 9.4e-146 | 479.7 | In-house | 1-297 (298) | alignment | ||
Range on Protein: 593-890
Range on HMM: 1-297/298.0
GNTEIQSENFNQTTQKLASVNRKFQMTGYALEFQRLNSFTSrEIPAEEKSVGEEPQNLQKNRFCDIVALNSCRVMLRKEHADEESDYINAVFLHAHRERN
|||||..|......||||.|..|...|||||||||||| .| ||..|||.|...|.| .|||..||.||.|.||.|.||.||||||||||.||||...||
gnteieaedlkaalqklaavkkkkkltgyalefqrlnsvss.eieeeekevarkpenkkkNRyadiialdssRvvLekedadeesdYiNAsflhaykgrn
AFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHELDQ-EYPQYWPDHGATKYGHIGVSVLSKQEKGDVISTKLEVTRKKVRrKTHEVRHLHHVSWPDK
||||||.|| |||||||||||..||||||||.||.|||. .|..||||.|...||.| ||.|||.|..|.|..||.|..||.. |..|||.||..|||||
afiatqaPltetvedFWrmvteedigtiVmltnleeldktkyhkywPdegketygeitvsllskeefadlivrklkvskkkee.kerevrqlhftsWpdk
CIPEVACSVLDLLDDVQTSQQQCGNAPVLVQCSNGVGRSGTFCVISSVIERLKTEQVIDVFQVIKRIRVNRPGAVESLTQYVFCYQIIQKYLGSFSDYA
..||.|.||||||..|..||||.||.||.||||.||||||||..|.||.||.|.|||.|||||.|..|..|||||.. .||||.|......| ||.|..
gvpenatsvldllrkvrasqqqagnkpvivqCsaGvgRsGtfiaidsvlervkkeqvvDvfqvvkvlRkkrpgavqteeqYvfiyeavlealdsfndei
|
|||||||||
0051299 | (Phosphotyrosine protein) phosphatases II | 593-883 | 2.4e-82 | 271.9 | In-house | 1-286 (288) | alignment | ||
Range on Protein: 593-883
Range on HMM: 1-286/288.0
GNTEIQSENFNQTTQKLAsvnrKFQMTGYALEFQRLNSFTSReipaEEKSVGEEPQNLQKNRFCDIVALNSCRVMLRKEHADEESDYINAVFLHAHRERN
|.|||. |.. .. .|| . ..||.. ||..| |.. . |.. |.||.|||. ||......|| |. .. .|.|||||| ... .. .
gdteisveellklvlkll....angltglleefeellsllpd....ltlsaallpenleknRysdilpydhsRVkLsvldgvegsdYinAsyidgynlkr
AFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHELD-QEYPQYWPDHGATKYGHIGVSVLSKQEKGDVISTKLEVTRKK---VRRKTHEVRHLHHVSW
.|||||.|| .||||||||| .... .||||..|.||. . ..||||..| ..||.| | || ....|.. ..||||... ....|.|.|. .|
kfIatqgPlpntvedFWrmvweqnvrvIvmltklvelgrekcaqYwplggsltygditvtllseevlddytvrtlevtnldlldgdgesrtvthfhytnw
PDKCIPEVACSVLDLLDDVQTSQQqCGNAPVLVQCSNGVGRSGTFCVISSVIERLKTEQVIDVFQVIKRIRVNRPGAVESLTQYVFCYQIIQKYL
|| ..|. . ..||.| .|..... |. ||.| ||.||||.|||... ..|.|..|...||....||.| |||.|... ||.|.|... ||
pdhgvpdspellldflrlvrkala.sgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlreqRpgmvqtpeqyrfvyealleyl
|
|||||||||
subfamily_PTPRB_pd | Subfamily PTPRB | 595-883 | 1.6e-63 | 209.4 | In-house | 5-285 (293) | alignment | ||
Range on Protein: 595-883
Range on HMM: 5-285/293.0
TEIQSENFNQTTQKLASVNrKfqmTGYALEFQRLNSFTSREipaeEKSVGEEPQNLQKNRFCDIVALNSCRVMLRKEHADEESDYINAVFLHAHRERNAF
..|. |.|.. .|... . . .... |...|... . . .... |...| .|||. .|.. . || | . . ...|||||| ... .. .. |
kpiklekfeehvkkmkads.d...lrfseeyeelkavgkdq....avkaaelavnraknrytnilpydhsrvkLaalkdesgsDYinanyipgynspref
IATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHELDQ-EYPQYWPDH-GATKYGHIGVSVLSKQEKGDVISTKLEVTRkkvRRKTHEVRHLHHVSWPDKC
|||| || |||.|||||| . .|||| .| | . .|||.. .. ||.| |......|. | . .|.... ......||..|..||||
iatqGPlpetvddfWrmvwekkssiivmltqlvekgkvkCeeYWPadeepvlyGdikvtlvaeeeledwvirelkiek...ekeerkvrqyhftsWpdhg
IPEVACSVLDLLDDVQTSQ-QQCGNAPVLVQCSNGVGRSGTFCVISSVIERLKTEQVIDVFQVIKRIRVNRPGAVESLTQYVFCYQIIQKYL
.|| . ..||.. |.... ... ..|..| || ||||.||| . .......|...|.| .. ..| .| | . .||.| .| ....|
vPektktlldfvrtvreaiektaskrPivvhCsaGvGRtGtfialdrllqaieeedyvdifgivaelReeRnllvqtekqYifihqcvldll
|
|||||||||
subfamily_PTPN6_pd | Subfamily PTPN6 | 595-884 | 4.2e-59 | 195.0 | In-house | 2-298 (306) | alignment | ||
Range on Protein: 595-884
Range on HMM: 2-298/306.0
TEIQSENFNQTTQKLASVNRKFQMTGYALEFQRLNSFTSREIpaEEKSVGEEPQNLQKNRFCDIVALNSCRVMLRkEHADEESDYINAVFLH--AHRERN
|.. ... .| ..| . ... .|. ||..|. ... ... |. |.| .|||. |. . ||.|. |. .|||||| ... .. ...
tsllakeieqrvselekeeeslekagfeeefeelqqeeakkl..lsrkegakpenkeknryknilPfDhtrvilk.epsvpgsdyinanyikkevkgsdk
AFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHELDQ-EYPQYWPDHGAT-KYGHIGVSVLSKQEKGDVISTKLEVTRKKVRRKTHEVRHLHHVSWPD
..|||| | .||.|||||| . . |||. . | . .||||. .. .||.| |. .|.... | | .| |..|| ....||...|. ||||
syiatqgclettvsdFWrmvwqensrvivmttkevErgkekCarYWPdeeekeeyGkisvtnvseksladYilRelsvskkkkkkeerevfqyhfksWPd
KCIPEVACSVLDLLDDVQTSQQQCG---NAPVLVQCSNGVGRSGTFCVISSVIERLKT---EQVIDVFQVIKRIRVNRPGAVESLTQYVFCYQIIQKYLG
. .|. |||.|.||.. |... . |..| ||.|.|| ||| || ... ... . ||. ...| .| | | | .|| | |..|.||.
hgvpkdpgavLdfledvnrkqeeleeaeagpivvhCsaGiGRtGtfiviDillkliekkgldadidiqklvksvreqrsglvqteqqykfvykaikkyie
|
|||||||||
subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 597-882 | 6.1e-41 | 134.9 | In-house | 9-282 (290) | alignment | ||
Range on Protein: 597-882
Range on HMM: 9-282/290.0
IQSENFNQTTqklaSVNRKFQMTGYALEF-QRLNSFTSREipAEEKSVGEEPQNLQKNRFCDIVALNSCRVMLRKEhadEESDYINAVFLHAHreRNAFI
.|.| |.. . | | .. ..| |. ..| . . |... .. ...|||. |.| . ||.|. . ||. | ... . ||
vqteafekfa....sdvvkknvdelakeyleklkpylpvq..ylerkifdkntefkknrykdvvcndktrvilkdG...ydGdyvhanyvkGl..kamfi
ATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHELDQ-EYPQYWPDHG--ATKYGHIGVSVLSKQEKGDVISTKLEVTRKKVRRKTHEVRHLHHVSWPDKC
|| .| .|| |.|||| . .. .|||| .| | . ||.|.. . .|.| | ...| . | |. |.| | | ..||. .|||||.
ltqGalkdtvidiwrmvlqekvaaivmlceliedGkakceqyypekeGevltfGeitvlcseeddkdaniikktlsvrdkdsGkehklkhlkikswpdks
IPEVACSVLDLLDDVQTSqqqcgNAPVLVQCSNGVGRSGTFCVISSVIERLKTEQVIDVFQVIKRIRVNRPGAVESLTQYVFCYQIIQKY
.. . ..| .| ... . || | || |.||.||| | .. | . .|. .... .| | ..|. .||. .|. ..
valstlallrtlrilrka.....sGpvvvhcsaGiGrtGtfvaievglqilldGkeldlldlvralrnsrlnsvqvdiqylalveilldl
|
|||||||||
0049772 | (Phosphotyrosine protein) phosphatases II | 608-884 | 4.7e-40 | 133.6 | In-house | 5-281 (314) | alignment | ||
Range on Protein: 608-884
Range on HMM: 5-281/314.0
KLASVNRKFQMTGYALEFQRLNSFTSREIPAEEKSVGEEPQNLQKNRFCDIVALNsCRVMLRKEHADEeSDYINAVFLHAHrerNAFIATQHPLLETVED
|||... .. . ....||. . . .|. |. . | |||. ||. . .||.| ... . |||||| ... . ..|||||.|| .||.|
plasfsellihddllklllvlnrrslsvlpeltilvadlflnrdknryldilpad.nrvilpglpvsg.sdyinasyvdgf...lkfIatqgpleitvvd
F----------WRMV--TDYDIGTIVM---------------------LNNLHEL-DQEYPQYWPDHGatkyghigvsvlskqekgdvistklE------
| |||| |... .||| |..| .. .. ....... |
freepvlyyngwrmvlrgdlnvrdivmsrdevladelsrLdaAlgKtpllildgngneptaadlellk.........................eelydpe
-VtrkkvrrkTHEVRHLHHVSWPDKCIPeVACSVLDLLDDVQTSqqqCGNAPVLVQCSNGVGRSGTFCVISSVIERLKteqViDVFQVIKRIRVNRP---
. .... ..... .|| . | ....|. ... . |||| |. |.||.|||.|. .. .|. | .. ......| ||
lf........erlgikylripvpDgsap.lledfdeflefieea...dkggpvlvHCkaGkgRtgtfvvaaylmkllg...v.sleealedvrlkRpinp
--GAVESLTQYVFCYQIIQKYLG
|..|.| ||.|.......||
npgfieqleqyefilealleylk
|
|||||||||
0036941 | (Phosphotyrosine protein) phosphatases II | 611-885 | 3.4e-77 | 255.0 | In-house | 5-279 (297) | alignment | ||
Range on Protein: 611-885
Range on HMM: 5-279/297.0
SVNRKFQMTGYALEFQRLnsftSREIPAEEKSVGEEPQNLQKNRFCDIVALNSCRVMLrkehADEESDYINAVFLHAHRERNAFIATQHPLLETVEDFWR
.......... ||..| . .. ..||.. |.||.|||. ||......|| | ||.|||||| .. .. ..|||||.|| .|||||||
llekllflalllkefeel....lpllllgslsvallpenleknRykdilpydhtRVkl....ddegsdYinAsyvdgydlkrkfIatqgPlpntvedFWr
MVTDYDIGTIVMLNNLHELDQ-EYPQYWPDH--GATKYGHIGVSVLSKQE--KGDVISTKLEVTRKKVRrKTHEVRHLHHVSWPDKCIPEVACSVLDLLD
|| .... .||||..| ||. ..||||. . .||.. | .|| .. ..|.. ..|||| .. ....|.|.|. .||| ..|| . |.||...
mvweqnvtvIvmltelvelgrekcaqywpleegesltygdftvtllsvevvllddytlrtlevtdtgng.esrtvthfhytgwpdhgvpespaslldfie
DVQTSQQQC-GNAPVLVQCSNGVGRSGTFCVISSVIERLK---TEQVIDVFQVIKRIRVNRPGAVESLTQYVFCYQIIQKYLGS
|.. ... .. |||| ||.||||||||... ....|. .|. .|.....| .| |||||..| ||.|.|......| .
lvrkvlkllpsggpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyeallellkk
|
|||||||||
0047943 | (Phosphotyrosine protein) phosphatases II | 612-883 | 2.3e-76 | 252.2 | In-house | 5-272 (273) | alignment | ||
Range on Protein: 612-883
Range on HMM: 5-272/273.0
VNRKFQMTGYALEFQRLNSFTSreipAEEKSVGEEPQNLQKNRFCDIVALNSCRVMLrkehADEESDYINAVFLHAHRERNAFIATQHPLLETVEDFWRM
.......|....||..| |.. ..||.. |.|..|||. ||......|| | |..|||||| .. .. ..|||||.|| .||||||||
lekllgltllleefelllslkp....lltysvallpenkdknrykdilpydhsrvkl....gdggsdyinAsyvdgynlkrkfiatqgPlpntvedfwrm
VTDYDIGTIVMLNNLHELDQ-EYPQYWPDHG---ATKYGHIGVSVLSKQEKGDVISTKLEVTRKKVRRkTHEVRHLHHVSWPDKCIPEVACSVLDLLDDV
| .... .||||..|.||.. ..||||. | ..||.. | .|| ..|.|.. ..||.|... ...|.|.|. .||| ..|. |.|.....|
vweqnvrviVmLtelvelgrekcaqYwpleggelsltygkftvtllseetkddytvrtleltnlgtge.srtvthfhytgwpdhgvppslesllefielv
QTSQQQC-GNAPVLVQCSNGVGRSGTFCVISSVIERLKTEQVIDVFQVIKRIRVNRPGAVESLTQYVFCYQIIQKYL
.. .... .| ||.| ||.||||.|||... ....|..|. .||....|..| |||.|... ||.|.|... .||
rkalealpsngpvvVHCsaGvgRtgtfialdllldqlekeggvdvleavkllrsqRpgmvqtpeqyrflyealleyl
|
|||||||||
0039614 | (Phosphotyrosine protein) phosphatases II | 612-886 | 2.6e-76 | 252.2 | In-house | 25-292 (297) | alignment | ||
Range on Protein: 612-886
Range on HMM: 25-292/297.0
VNRKFQMTGYALEFQRLNSFTSreipaEeKSVGEEPQNLQKNRFCDIVALNSCRVMLRKEHA-DEESDYINAVFLHAHRE-RNAFIATQHPLLETVEDFW
.......|.. |||..| |.. . .|... |.| |||. ||......|| | | |..|||||| .. .. ..|||||.|| |||||||
lekansktllllefeellslkp.....d.ysiallpenkdknrykdilpydhsrvklkpedgvdldsdYinAsyvdgydlltrkfIatqgPlpetvedFw
RMVTDYDIGTIVMLNNLHELDQEYPQYWPDHGAtKYGHIGVSVLSKQEKGDVISTKLEVTRkkvRRKTHEVRHLHHVSWPDKCIPEVACSVLDLLDDVQT
||| .... .||||..| ||.. ..||||. | .||.. | .|. ....... ..||||. ....|.|.....||| ..|. . ..|..|. |..
rmvweqgvtvivmLtklvelgrkcaqywpeegg.tygdftvtllkvehldgytvrtlevtn...ngesrtvthfqytgwpdhgvppslellleflelvre
SQQQC-GNAPVLVQCSNGVGRSGTFCVISSVIERLKTEQVIDVFQVIKRIRVNRPGAVESLTQYVFCYQIIQKYLGSF
.... .. |||| ||.||||.|||... ..|.|..|. .||....|..| |||||... ||.|.|......| .
alaelpkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavqtpsqyrflydallellkrk
|
|||||||||
subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 612-889 | 4.5e-67 | 220.9 | In-house | 13-289 (290) | alignment | ||
Range on Protein: 612-889
Range on HMM: 13-289/290.0
VNRKFQMTGYALEFQRLNSFTSReipaEEKSVGEEPQNLQKNRFCDIVALNSCRVMLR--KEHADEESDYINAVFLHAHRERNAFIATQHPLLETVEDFW
... ...|. .|..|.|. | .. || ..| ..||| .|| . |..|| .| | . .||||.... ..|....|||| |. .|. |||
nghakgnegfrnqfkmldsgese....htvtvgltssnkllnRfanivvyddnritLrpisghkDCtneyinAcyikgykekkqyiatqgpvsntlvdFW
RMVTDYDIGTIVMLNNLHELDQE-YPQYWPDHGATKYGHIGVSVLSKQEKGDVISTKLEVTRKKVRRKTHEVRHLHHVSWPDKC-IPEVAcSVLDLLDDV
... . .. |||| | | ... |||||.....||.. . .|. .. . | .||||. |. ....| ... .|... ... . ..| .. .
kliwqekvtiivmltniieegkvkCqqYWpdsdtkaygefsikllneetlneyierklevknknsagakqsvtqyqitnwdstgkvtnpq.tillvieem
QTSQQQCGNAPVLVQCSNGVGRSGTFCVISSVIERLKTEQVIDVFQVIKRIRVNRPGAVESLTQYVFCYQIIQKYLGSFSDY
. | . || ...| ||..||||..||.. |.. |||.|||||||.|. |. .|| |.. || . .||. .|| ||. |
yktqrkrgntsivvHCSdtvgrsavfcaaattinkcktegvidvfqvlksqRiqkpgsvqtvqqyqgifqivltyldsfety
|
|||||||||
0043336 | (Phosphotyrosine protein) phosphatases II | 614-883 | 3e-72 | 238.7 | In-house | 15-277 (278) | alignment | ||
Range on Protein: 614-883
Range on HMM: 15-277/278.0
RKFQMTGYALEFQRLNSFTSreipaEEKSVGEEPQNLQKNRFCDIVALNSCRVMLRKEHADEESDYINAVFLHAHRERNAFIATQHPLLETVEDFWRMVT
. |.. |||..|.||. ...|... |.| .|||. ||......|| | . |. |||||| .. .. ..|||||.|| ||||||||||
llnlktllllefeellsfkl.....dtysiallpenkdknrykdilpydhsrvklsllggdldsdYinAsyvdgynvprkfiatqgPlpetvedFwrmvw
DYDIGTIVMLNNLHELD-QEYPQYWPdHGATKYGHIGVSVLSKQEKGDVISTKLEVTRkKVRRKTHEVRHLHHVSWPDKCIPEVACSVLDLLDDVQTSQQ
.... |||||..| ||. . . |||| | ..||.. | .|. ....|.. ..||||. . ....|.|.|...||| ..|| ..||.| .|.. ..
elgvttivmLtelvelgrvkcaqYwp.ggsltygdftvtllkeehlddytvrtlevtn.lgdgesrtvthyhylgwpdhgvpeslsllldflkavreale
qCGNAPVLVQCSNGVGRSGTFCVISSVIERLKTEQVIDVFQVIKRIRVNRPGAVESLTQYVFCYQIIQKYL
| |||| ||.||||.|||... ..|.|..|. .|.....|..| |||||... ||.|.|.... ||
.dsngpvlVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqRpgavqtpsqyrflyealleyl
|
|||||||||
subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 614-892 | 2.3e-67 | 222.0 | In-house | 15-287 (287) | alignment | ||
Range on Protein: 614-892
Range on HMM: 15-287/287.0
RKFQMTGYALEFQRLNSFTSREipaEEKSVGEEPQNLQKNRFCDIVALNSCRVMLRkehaDEESDYINAVFLHAHRERNAFIATQHPLLETVEDFWRMVT
.. .|. |. |.. | || .| .. .|| .|||. .|. . ||.|. .|. |||||||. ...|..|||... |. .|. .||...
hakgnegfknqftvleqvtqre...devthniasqnkdknRltqilvpdnyrvllk....gehpdyinavfidgykekkafiiaesPmfntarnfWklid
DYDIGTIVMLNNLHELDQEY-PQYWPDHGATKYGHIGVSVLSKQEKGDVISTKLEVTRKKVRRKTHEVRHLHHVSWPDKC-IPEVACSVLDLlDDVQTSQ
| . .|||| ...| |.| ||||.. .. .|. ...|... . ..| ||||..|. ....|. . .|... ..| . ..| . .. .|
drnvtaivmlcqekendeevcyqyWpeeksvvlGeyniellneevnagyierklevknknkagdkqqvkqyqitnWdstgkvtepqtillvi.eemyktq
QQCGNAPVLVQCSNGVGRSGTFCVISSVIERLKTEQVIDVFQVIKRIRVNRPGAVESLTQYVFCYQIIQKYLGSFSDYANF
.. ||....| ||..||||..|| . |.. ||| |||||||.|. |. .||.| .|| | ..|...|| ||. |..|
rkrgntsivvhCsdtvGrsamfcaaattinkckteGviDvfqvlksqriqkpgsvqtveqykfindivleyldsfetysdf
|
|||||||||
subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 614-890 | 1.1e-60 | 200.6 | In-house | 27-299 (319) | alignment | ||
Range on Protein: 614-890
Range on HMM: 27-299/319.0
RKF--QMTGYALEFQRLnsfTSREIPAEEKSVGEEPQNLQKNRFCDIVALNSCRVMLRKEHADEESDYINAVFLHAHRERNAFIATQHPLLETVEDFWRM
..| ..| . ||.|. . . .. ... . .|| |||. .|.| . .| |.. | |||||| |. .. .. .||.| || .|..|||||
sdfdddltklevefrra...cklgvnladqtfanldqnkdknriinilafdknvvklerliGeefsdyinasfvtGyqrkdkyiaaqGPldntladfWrm
VTDYDIGTIVMLNnlhelDQEYPQYWPDHGATKYGHIGVSVLSKQEKGDVISTKLEVTRKKVRRKTHEVRHLHHVSWPDKCIPEVACSVLDLLDDVQ-TS
. .|.. |||.| . |||| .. |... |.| | .| . . ..|.... . ... | |||. |. . .. |.. |.
iweyncstivllt.....kdkcsqywplkivikeerfkvkvdsveetaeyvvrdielsedgkekdirkitqfhflGwpdvGvpdypsdlmrlvkkvrhlt
QQQCGNAPVLVQCSNGVGRSGTFCVISSVIERLKTEQVIDVFQVIKRIRVNRPGAVESLTQYVFCYQIIQ-KYLGSFSDYA
... ..|...| || ||||.|.. |. ...|.| |. .||..... .| .|. |..|.|| |.| . ..| ..|| |
skenhranivvhcsaGvGrtGvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysalleehlfghsdva
|
|||||||||
subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 614-883 | 1.9e-58 | 192.8 | In-house | 10-276 (281) | alignment | ||
Range on Protein: 614-883
Range on HMM: 10-276/281.0
RKFQMTGYALEFQRLNSFTSREiPAeekSVGEEPQNLQKNRFCDIVALNSCRVMLRKEHADEESDYINAVFLHAHRERNAFIATQHPLLETVEDFWRMVT
.. . .|.. |.. |.. .. .| . ....| .|||. .||| . || . ........||||| |. . .. ...|||| |. .....||.||
sqndnaGfieeyeklaaigvdn.ta...taskadenvlknrYsnivaYDatrvkvtpneenkntDYinanfvpgykgekeyiatqgPvPaslvafWqmvw
DYDIGTIVMLNNLHELDQ-EYPQYWPDHG-ATKYGHIGVSVLSKQEKGDVISTKLEVTRKKvrRKTHEVRHLHHVSWPDKCIPEVACSVLDLLDDVQTSQ
.... .|||. . | .. .||||. ..|||.. |. ....|| |. |....|.. .| ||..|....|||. .|. . .|. ..|. .
eqkvsaivmvtreieagklkChrYWPddnselkygdvtvkstaeeekatyierkfkleres..getreveqlaytaWPdhGvPattkellefrkevlklt
QQCGNAPVLVQCSNGVGRSGTFCVISSVIERLKTE-QVIDVFQVIKRIRVNRPGAVESLTQYVFCYQIIQKYL
.. .||... || ||||.||. . .......| . .|| .|.. .| .| | ...|| | |... ..|
ekktkaplvihCsaGvGrtGtyialDrlvkaveaeleeldvkavvaelrkernlmvqtvvqyefvykavldal
|
|||||||||
0040438 | (Phosphotyrosine protein) phosphatases II | 616-883 | 5.9e-77 | 254.4 | In-house | 15-276 (317) | alignment | ||
Range on Protein: 616-883
Range on HMM: 15-276/317.0
FQMTGYALEFQRLNSFtsreiPAEEKSVGEEPQNLQKNRFCDIVALNSCRVMLRKEHADEESDYINAVFLHAHRERNAFIATQHPLLETVEDFWRMVTDY
..|. ||..| |. . .. ||.| |.| .|||. ||. . ..|| | . |..|||||| . . ......|||||.|| .||||||||| ..
sdftalleefedllsl.....kldtysvaelpenkdknrypdilpydhsRVkLsplggdldsdYInAsyvdgpnlkrkfIatqgPlpntvedFwrmvweq
DIGTIVMLNNLHELD-QEYPQYWPDHGATKYGHIGVSVLSKQEKGDVISTKLEVTRKkVRRKTHEVRHLHHVSWPDKCIPEVACSVLDLLDDVQTSQQqC
....||||..| ||. . . ||||. . ..||.. | .|| .|..... ..|||. . ....|.|.|. .||| ..|. ..||.|. |.....
gvtvivmLteleelgrekcaqYwplgetltygdftvtllseeelagitlrtlevedl.gdsesrtvthfhytgWpdhgvppspdllldfleavreale.d
GNAPVLVQCSNGVGRSGTFCVISSVIERLKTEQVIDVFQVIKRIRVNRPGAVESLTQYVFCYQIIQKYL
.. |||| ||.||||.|||... ..|.|..|. .||....|..| |||||... ||.|.|.....||
pggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrflydalleyl
|
|||||||||
subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 616-880 | 4.1e-71 | 234.4 | In-house | 18-276 (288) | alignment | ||
Range on Protein: 616-880
Range on HMM: 18-276/288.0
FQMTGYALEFQRLNSFTSreipAEEKSVGEEPQNLQKNRFCDIVALNSCRVMLRKEHADEESDYINAVFLHAHRERNAFIATQHPLLETVEDFWRMVTDY
. ||. |.. | .. . .....|....| .|||. .|.... || |.| . ...||||| ... .......|||| || .||.|||..| ..
rnrtgfseeynsLaalek....tksvtagrlavnakknRyrnilpyDekrvklkkleeeagaDYinasyidgekkkkkyiatqgPladtvndfWelvyen
DIGTIVMLNNLHELD-QEYPQYWPDHGA-TKYGHIGVSVLSKQEKGDVISTKLEVTRKKVRRkthEVRHLHHVSWPDKCIPEVACSVLDLLDDVQTSQQQ
.. |||||..| | . .. .|||| . ..||.. | .....|..|.. ||.. .|| .. |. .... .|||. .|| . .|.||. |....|.
ktstivmltelveggktkCeeYWPdadkpknyGsvtvtlveskeledfvlrklllekkktel...eitqyqylaWpdhgvPeskapllellrqvkvanqa
CgNAPVLVQCSNGVGRSGTFCVISSVIERLKTEQVIDVFQVIKRIRVNRPGAVESLTQYVFCYQIIQ
|..|.||.||||.||| .. .|.....|..|||. .....| .|. |. |.||.|.|...
d.tgpiivhCsaGvGrtgtFialdalidaveeedyiDvagtvaklRkqRallvqtlkqYefiyevll
|
|||||||||
subfamily_CG7180_pd | Subfamily CG7180 | 617-883 | 4.4e-56 | 184.7 | In-house | 11-290 (296) | alignment | ||
Range on Protein: 617-883
Range on HMM: 11-290/296.0
QMTGYALEFQRLNSFTSReIPAEEKSVGEEPQNLQKNRFCDIVALNSCRVMLRKEHADEESDYINAVFLHAHRERNAFIATQHPLLETVEDFWRMVTDYD
.. . .|.. . |.| . .. | . .|..||| ..| . ||.|.| . .|.|||||||. .. ...| |. | |||..|||.| | .
krrkfrveyklelkltpr.leigdCagglrkenreknrdvkvvPyDynRvvLekldGeeksdYinavyvdsflkkkeyivteapkketvdefWrlvydee
IGTIVMLNNLHELDQEYPQYWPDHGATKYGHIGVSVLSKQEKGDVISTKLEVTRK---------KVRRKTHEVRHLHHVSWPD-KCIPEVACSVLDLLDD
| ..|.| . . . ||.||| .. ..||.| | ...... .. . .. .|.| .| .| |.... |. . .| .. ....|.
isavvvLtktfdfakmypsywpnkskeqygeifveiveekqyanlkirtfkltkkivalteqekqvkaetRivklfqlteWeledkvPlstnalielrrr
VQTSQQQC----GNAPVLVQCSNGVGRSGTFCVISSVIERLKTEQVIDVFQVIKRIRVNRPGAVESLTQYVFCYQIIQKYL
|.. ... ..||.| .|.|..||| .. | .| .. |. .|||. .|..| .||. ||. ..| ..|.......
vrlwrekvdedpeegPvvvvssdGasRsGvylaidanlelvekeeevdvFeavktlrrsRpqLvenveeYkyiYdvlleav
|
|||||||||
subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 618-887 | 1.3e-77 | 256.0 | In-house | 22-287 (319) | alignment | ||
Range on Protein: 618-887
Range on HMM: 22-287/319.0
MTGYALEFQRLNSFTSReipaeEKSVGEEPQNLQKNRFCDIVALNSCRVMLRKEHADEESDYINAVFLHAHRERNAFIATQHPLLETVEDFWRMVTDYDI
.|. . ||. |. .. . . ....| .|||. .|.| . .||.| . . |.|||||| |. ...||..||||| || .|.||||||| ....
etllekefkllkeavnd.....tfdsaskeenkkknryqnilaydrtrvvlseldgvegsdyinasfidgyqerekfiatqaPlentiedfWrmvWeees
GTIVMLNNLHE-LDQEYPQYWPDHGATKYGHIGVSVLSKQEKGDVISTKLEVTRKKVRRKTHEVRHLHHVSWPDKCIPEVACSVLDLLDDVQTSQQQCGN
..|||..| | |. .. .|||.. ..||.. | .....|. |.| ||.. .|. .| || | .. .|||. .|| | |.|||| ... |... .
sivvmltklveklkvklkkywpeenfeeyGrlivtleeeeeledyiirklklnkkssevetRevkhfqyteWpdhdvPekatslldllkrirksrektqs
APVLVQCSNGVGRSGTFCVISSVIERLKTEQVIDVFQVIKRIRVNRPGAVESLTQYVFCYQIIQKYLGSFS
|. | ||.|||| |||.|.. ..||.| |.|.|||....|.|. |. |. || |.|... ... ...
gPivvhCsaGvGRtGtfivldamlervkeegvlDvfstvsrlRtqRnimvqrpeqYkfiyealleaveagd
|
|||||||||
0045450 | (Phosphotyrosine protein) phosphatases II | 618-883 | 1.4e-73 | 243.6 | In-house | 26-304 (307) | alignment | ||
Range on Protein: 618-883
Range on HMM: 26-304/307.0
MTGYALEFQRLNSFTSREipAEEKSVGEEPQNLQKNRFCDIVALNSCRVMLRKEHAD-EESDYINAVFL--------HAHRERNAFIATQHPLLETVEDF
.||.. ||..|.|.| . | |... |.| |||. ||......|| | .. . |.|||||| . . .. ..|||||.|| ||||||
ltgllkefekllsvtvfl..lgeysiallpenkdknrykdilpydhtRVklssldgsledsdYiNAsyvrvpllllldgydlkrkfIatqgPlpetvedF
WRMVTDYDIGTIVMLNNLHELDQE-YPQYWPDHGAT-KYGHIGVSVLSKQEKGDVISTKLEVTRKKVRRKTHEVRHLHHVSWPDKCIPEVACSVLDLLDD
|||. ......||||..| ||..| ..||||| | . ||.. | .||........ ..||||... ....|.|.|. .||| ..|. ..||...
wrmlweqgvtvivmltelvelgrekcaqywPdegeeltygnftvtllseehldgytvrtlevtdldgtgesrtvthfhytgwpdhgvppsfeelldfiee
VQTSQQQC-GNAPVLVQCSNGVGRSGTFCVISSVIERLKTEQV---IDVFQVIKRIRVNRPGAVESLTQYVFCYQIIQKYL
|.. .... .. |||| || ||||.|||... ....|..|.. .|.....|..| |||||... ||.|.|......|
vrkaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrflyeallell
|
|||||||||
subfamily_Ptp69D_pd | Subfamily Ptp69D | 619-883 | 1.7e-70 | 232.6 | In-house | 22-286 (307) | alignment | ||
Range on Protein: 619-883
Range on HMM: 22-286/307.0
TGYALEFQRLNSFtsrEIPaEEKSVGEEPQNLQKNRFCDIVALNSCRVMLRKEHADEESDYINAVFLHAHRERNAFIATQHPLLETVEDFWRMVTDYDIG
|.| |...|.. ||. . .|.|. |. |||. ||.| .. ||.|.| .|.|||||| |.....|.. ||| | |. .|..|||||... ..
fglakeyekLear...eid.kstkvsekkenalknRyedikafDktRvkLkkingkedsdYinasfikgykekkkfiaaqdPveatigDfWRmiaeqevt
TIVMLNNLHELDQE-YPQYWPDHGATKYGHIGVSVLSKQEKGDVISTKLEVTRKKV----RRKTHEVRHLHHVSWPDKCIPEVACSVLDLLDDVQTSQQQ
.|||| || | ... ..|||. ..||.| | . |.....| | .|.|..|| ....| |. .|.| .|||| ..|.|.. |. ...
livmlsnlteknrkkcakYWpiedevqygdilvklvseekhsdyiiReldvskkkeesgevedsrkvvqyhytgWkDskvPevargllklieqvrelykl
CgNAPVLVQCSNGVGRSGTFCVISSVIERLKTEQVIDVFQVIKRIRVNRPGAVESLTQYVFCYQIIQKYL
..|..| ||.||||||.| ..|....||.|. .|.|...| .| .|. |.|| ||||.|. . .|
n.rsPivvhCsaGvgrsgifvaldsllqqlkaedkvdifetvkdLrsqRnllvqsleqYvflyralldys
|
|||||||||
subfamily_PTPRG_pd | Subfamily PTPRG | 619-884 | 1.6e-63 | 209.8 | In-house | 19-288 (563) | alignment | ||
Range on Protein: 619-884
Range on HMM: 19-288/563.0
TGYALEFQRL-NSFTSREIPAEEksvGEEPQNLQKNRFCDIVALNSCRVMLRKEHADEES-DYINAVFLHAHRERNAFIATQHPLLETVEDFWRMVTDYD
.|.. ||. | . .|....|| ..|.| .||| ..||| .. || |.. ... ||||| ... .. .||||||.|| .|..|||||. .
igfseefealqsetiskdldaeh...sqkpenkrKnRylnivaydrsRvklsplpgkkkklDYinAnyidGyqkskafiatqgplkdtfddFWrmiWeqn
IGTIVMLNNLHEL-DQEYPQYWPDHGATKYGHIGVSVLSKQEKGDVISTKLEVTRKKVRRK-----THEVRHLHHVSWPDKCIPEVACSVLDLLDDVQTS
.|||. || | .. ..||| .. .||.. | ... . . .| . |...| ..||. | .|||.. || . || ...
vaiivmitnlvergrrkcdvYWPkdesetygalqvtlieeevlalytvrtlviknlklkkkkqcdteklvrqyhytkWPdhgvPehslpvLifvkkssaa
QQQcGNAPVLVQCSNGVGRSGTFCVISSVIERLKTEQVIDVFQVIKRIRVNRPGAVESLTQYVFCYQIIQKYLG
... |..| ||.||||.||..|..........|....||...|.|| .|. |.. ||.| ...... .
nka.eaGPivvHcsaGvgrtGtyivldtllkqiqqenavnvfgflkhiraqRnflvqteEqYiflhdalleaia
|
|||||||||
subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 619-883 | 6.5e-63 | 207.8 | In-house | 23-288 (325) | alignment | ||
Range on Protein: 619-883
Range on HMM: 23-288/325.0
TGYALEFQRLNSFTsreipAEEKSVGEEPQNLQKNRFCDIVALNSCRVMLRKEHADEESDYINAVFLHAHRERNAFIATQHPLLETVEDFWRMVTDYDIG
|.| ||. | | . | | |.| .|||| ..|||. ||.| . | .|||||| .|. ..... |.|.| || .|..|.||.| |.
dgfahefgllpsdd.....giakkvamkpenkaknrfknvvaldksrvvletkkddpssdyinasylrddkkkdvflaaqaPltatindlWrlvldWrcs
TIVMLNNLHELDQEYPQYWPDH--GATKYGHIGVSVLSKQEKGDVISTKLEVTRKKvRRKTHEVRHLHHVSWPDKCIPEVACSV---LDLLDDVQTSQQQ
.|.|| | . ... .|||.. . ..| . |.. . .| | . .|.| . | . .| |. ... ||.| .. ... |.|.. |. .
vvvvlneldlgkdrcavywpkemgksktfGglevklrtieeisdyvhrvldvkqvk.kGetrsvkqfqlqswddmGvqkrpatlisilqlvkavservta
--CGNAPVLVQCSNGVGRSGTFCVISSVIERLKTEQVIDVFQVIKRIRVNRPGAVESLTQYVFCYQIIQKYL
. .|.|| ||.||||.|.| . |..... .| .|.|...|..| .|| ||. ||...|. . ...
ntkastpilvhcsaGvGrtGvfislysalakvieesrvdifgfvkklrkdrpsmvetvdqyiliyealveay
|
|||||||||
subfamily_PTPN12_pd | Subfamily PTPN12 | 619-883 | 4.5e-62 | 204.6 | In-house | 8-277 (290) | alignment | ||
Range on Protein: 619-883
Range on HMM: 8-277/290.0
TGYALEFQRLNSFTSREIPAE--EKSVGEEPQNLQKNRFCDIVALNSCRVMLRKEHADEESDYINAVFLHAHRERNAFIATQHPLLETVEDFWRMVTDYD
.| |||.| . ... . ....||...| .|||. ||. . ||.|.|.. .|.|||||| |.. .. ..||.| || .|..|||||. ...
eefakefqklkklsekykaekvysteagekeenvkknrykDilPydksrvelskieeeegsdYinanfikgvegkleyiaaqgPLpktlddfWrmiwekn
IGTIVMLNNLHELDQEY-PQYWPDHGAT--KYGHIGVSVLSKQEKG-DVISTKLEVTRKkvrRKTHEVRHLHHVSWPDKCIPEVACSVLDLLDDVQTSQQ
. .||. .. ||.. .|||..| . ..|.. |.. ... | . |.|... .....|. .|. .|||. .|. | |.|.|...|.. |.
veivvmaCrevelgkkkCerYWpeegeeelefgefevtleeekavdddflirtLkveaq...kesrkvyqfhYtaWPDhgvPssaksllelielvrelqe
qCGNAPVLVQCSNGVGRSGTFCVISSVIERLKTEQV---IDVFQVIKRIRVNRPGAVESLTQYVFCYQIIQKYL
.||..| || |||| || ..| | | ||.|.. .|||... ..| .|. .| . ||.. |. . ...
.sedaPlvvhCsaGvGrtGtiiaidyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavaelv
|
|||||||||
subfamily_PTPN23_pd | Subfamily PTPN23 | 619-882 | 7.7e-54 | 177.4 | In-house | 15-279 (288) | alignment | ||
Range on Protein: 619-882
Range on HMM: 15-279/288.0
TGYALEFQRLNSFTSREipAEEKSVGEEPQNLQKNRFCDIVALNSCRVMLRkehaDEESDYINAVFLHAHR-ERNAFIATQHPLLETVEDFWRMVTDYDI
|. .|. |.. .| |...|. . .|||. ||. .. ||.|| ... ||||| |.. ||||| || .|. |||.|| .
taldkkfkeleqkqdke..arkrsiaiaklyseknrsrdilPyDhnRvklr....gskDDYinAsfvkdlspgcPdfiatqaPlqstlnDFWlmvyeqks
GTIVMLNNLHELDQE-YPQYWPDH--GATKYGHIGVSVLSKQEKGDVISTKLEVTRKKVRrKTHEVRHLHHVSWPDKCIPEVACSVLDLLDDVQT---SQ
.|||| . .||... .||| . ..|.|.. |.. |..| . .. .|... .... ....|.||. |||. .|. ..|..|| |.. ..
sviVmllskeelgkpkvdrYwPedkgetvkfgdlsvtlksvretethvervlkletldad.avksvshlqltsWpelGvPasPetllqfldevesayeav
QQCGNAPVLVQCSNGVGRSGTFCVISSVIERLKTE-QVIDVFQVIKRIRVNRPGAVESLTQYVFCYQIIQKY
|. ..|..|.|| ||||.|.|... .... |... ..|. ||..|.| .| |. .|. |.|... ..
qrksktPlvvhCsaGvgRtgvfalvyaavrelekgnglldiiqvvsrlreqRrfmvqekeqlkfsyeavlea
|
|||||||||
0046845 | (Phosphotyrosine protein) phosphatases II | 623-888 | 2.9e-79 | 261.7 | In-house | 4-279 (284) | alignment | ||
Range on Protein: 623-888
Range on HMM: 4-279/284.0
LEFQRLNSFTSREIpaEEKSVGEEPQNLQKNRFCDIVALNSCRVMLRKEHAD-EESDYINAVFLHAH-----RERNAFIATQHPLLETVEDFWRMVTDYD
||..|.|.| . . ||. |.|| |||. ||......|| |. .. | |.|||||| ... . . ...|||||.|| .||||||||| ...
eefeellsltvkll..lslsvallpenlsknRykdilpydhsRVklksldgdledsdYinAsyvdgydldltyikkkfIatqgPlpntvedFwrmvweqn
IGTIVMLNNLHELDQ-EYPQYWPDHG-ATKYGHIGVSVLSKQEKGDVISTKLEVTRKKVRRKTHEVRHLHHVSWPDKCIPEVACSVLDLLDDVQTSQQQ-
. .||||..|.| .. ..||||. | .||.. | .||...|.|.. ..||.|.... ....|.|.|. |||| ..|. . ..|..|..|......
vrvIVmltelvengrekcaqYwplegevltygdftvtllseevkddytvrtleltnlgytgesrtvthfhytswpdhgvppspedlleflrlvrellenl
CGNAPVLVQCSNGVGRSGTFCVISSVIERLKTEQ---VIDVFQVIKRIRVNRPGAVESLTQYVFCYQIIQKYLGSFSD
|. |..| ||.||||.|||... ..|.|..|. ..||....||.| |||.|..| ||.|.|.... || ..
pgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvqtleqyrfvyealleylklklt
|
|||||||||
subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 624-893 | 9.2e-80 | 263.1 | In-house | 25-290 (318) | alignment | ||
Range on Protein: 624-893
Range on HMM: 25-290/318.0
EFQRLNSftSREIPAEEKSvgEEPQNLQKNRFCDIVALNSCRVMLRKEHADEESDYINAVFLHAHRERNAFIATQHPLLETVEDFWRMVTDYDIGTIVML
|..||. |.| ... || || | .|||. .|.| ...|| |.. . .|.|||||| .. .|...|.||.| || ||.||||||| . . .||||
eyerlsr..seetvtslks..lepvnkaknryanilaydhtrvkLqmlegeegsDyinanyidGyrrkkayiaaqaPlpetieDfWrmvWeqnsavivml
NNLHELDQ-EYPQYWPDHGATKYGHIGVSVLSKQEKGDVISTKLEVTRKKVRrKTHEVRHLHHVSWPDKCIPEVACSVLDLLDDVQTSQQQCGNAPVLVQ
...| . .|||..|...||.. | . .. | .| . ...|||... .. .|| |. ||||. .|| ..|.|||. .|.. ||..|. |..|
tqeeergkakvhryWPskgsrsygklvvelkeevelsdyvlrefkvtrteee.esrqvrqyhytsWpdegvpesgaslldlvrqvskaqqksgagpivvh
CSNGVGRSGTFCVISSVIERLKTEQVIDVFQVIKRIRVNRPGAVESLTQYVFCYQIIQKYLGSFSDYANFS
|| |||| |.|.......||.| |...||||..|..| .|. | ||.|.|......| |. ... |
CsaGvGrtGvfiavdillerikaealvDvfqtvkqlreqrnlmvqtedqyefiydvllealasgdtevdas
|
|||||||||
DSPc_SM00195 | 624-883 | 6.4e-74 | 244.0 | In-house | 5-262 (263) | alignment | |||
Range on Protein: 624-883
Range on HMM: 5-262/263.0
EFQRLNSFTSREipaeEKSVGEEPQNLQKNRFCDIVALNSCRVMLRKEHADEESDYINAVFLHAHRERNAFIATQHPLLETVEDFWRMVTDYDIGTIVML
||..|.. || . |.. .|...| .|||. .|. .. || | ||. .|.|||||| .. .......||||.|| .|||||||||.. .. .||||
efekleestspk....etteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivml
NNLHEL-DQEYPQYWPDH--GATKYGHIGVSVLSKQEKG-DVISTKLEVTRKKVrRKTHEVRHLHHVSWPDKCIPEVACSVLDLLDDVQTSQQQCgNAPV
.. | .. .|||. | ...|.| | . ....| ..| ..||.| .. ..|..|..... .|||. .|. . |||.|| |..|... ..|.
teeeengkekcdrywpeesggketfgkisvklvevekkkdeiilrtleltkegk.eetrkvtqyqyknWpdhgvpdstksvlellravkksksts.sgpi
LVQCSNGVGRSGTFCVISSVIERLKTEQVIDVFQVIKRIRVNRPGAVESLTQYVFCYQIIQKYL
.|.||.||||.|||..|......|..|. .|.|...|..| .|||.|..|.|| |.|..| .|.
vVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaileyi
|
|||||||||
PTPc_SM00194 | 624-883 | 6.4e-74 | 244.0 | In-house | 5-262 (263) | alignment | |||
Range on Protein: 624-883
Range on HMM: 5-262/263.0
EFQRLNSFTSREipaeEKSVGEEPQNLQKNRFCDIVALNSCRVMLRKEHADEESDYINAVFLHAHRERNAFIATQHPLLETVEDFWRMVTDYDIGTIVML
||..|.. || . |.. .|...| .|||. .|. .. || | ||. .|.|||||| .. .......||||.|| .|||||||||.. .. .||||
efekleestspk....etteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivml
NNLHEL-DQEYPQYWPDH--GATKYGHIGVSVLSKQEKG-DVISTKLEVTRKKVrRKTHEVRHLHHVSWPDKCIPEVACSVLDLLDDVQTSQQQCgNAPV
.. | .. .|||. | ...|.| | . ....| ..| ..||.| .. ..|..|..... .|||. .|. . |||.|| |..|... ..|.
teeeengkekcdrywpeesggketfgkisvklvevekkkdeiilrtleltkegk.eetrkvtqyqyknWpdhgvpdstksvlellravkksksts.sgpi
LVQCSNGVGRSGTFCVISSVIERLKTEQVIDVFQVIKRIRVNRPGAVESLTQYVFCYQIIQKYL
.|.||.||||.|||..|......|..|. .|.|...|..| .|||.|..|.|| |.|..| .|.
vVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaileyi
|
|||||||||
subfamily_PTPN13_pd | Subfamily PTPN13 | 624-884 | 4e-46 | 152.5 | In-house | 16-270 (273) | alignment | ||
Range on Protein: 624-884
Range on HMM: 16-270/273.0
EFQRLNSFTsreiPAEEKSVGEEPQNLQKNRFCDIVALNSCRVMLRKEHAdeesdYINAVFLHAH--RERNAFIATQHPLLETVEDFWRMVTDYDIGTIV
||. |. . | .. .||.. .| .|||. ... . || | .| . |||| ..... .. .||.| || |||.|||.|| . . |.
efkelrelk....pldtcevgkkkenkdknryrnvlPydetrvklgdegg.....yinaslikvpvgkdeyeyiacqGPlPetvkdfwqmvweqkaevia
MLNNLHELDQ-EYPQYWPDHGATK---YGHIGVSVLSKQEKGDVISTKLEVTRKKVrRKTHEVRHLHHVSWPDKCIPEVACSVLDLLDDVQTSQQqcGNA
|. . | .. .|||.. | .. . |..| |.. . .|.|. .. ....|| ||. |.||| .| | ..| .. |.. |. ..
mvtlekekgkvkchrywPesknkklkvsnrlevellkvqkldgfvvralavkdses.gesrevahlnfvkwPdhgvPssaaellqfvaevrrlqt..dag
PVLVQCSNGVGRSGTFCVISSVIERLKTEQVIDVFQVIKRIRVNRPGAVESLTQYVFCYQIIQKYLG
|..| || |.|||||. .| |.. .. .. .|| ......| | | | . ||.|.|..| . |.
PivvhcsaGiGrsGtlitidvvlglierdkefdvkeivrklreqrqgvvqtkdqyifvykailevlk
|
|||||||||
subfamily_PTPRA_pd | Subfamily PTPRA | 629-882 | 1.1e-75 | 249.6 | In-house | 39-294 (330) | alignment | ||
Range on Protein: 629-882
Range on HMM: 39-294/330.0
NSFTSREIPAEEKSVgEEPQNLQKNRFCDIVALNSCRVMLRKEHADEESDYINAVFLHAHRERNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHE
|.. . .| | . .. .| .|||. .|. . ||.| . . |||||||| |.. ..|.. |||.| |. |||||||||. ... ||||| .|.|
nalPagpiqatlela.skeenkeknrvvnilPydfsrvilsvkeGveesdyinasfidGykekdkfiaaqGPkeetvedfwrmiweqksativmltelke
LDQEY-PQYWPDHGATKYGHIGVSVLSKQEKGDVISTKLEVTR---KKVRRKTHEVRHLHHVSWPDKCIPEVACSVLDLLDDVQTSQQQCGNaPVLVQCS
..| |||||.|. ||.| |.| ... |. |. |.. .. ..|. || .| |||| .| . .|.|| |.. .|| .. |. | ||
rkeekcaqywPdeGlvtyGnirvevedetvlvdytvrkflvqqlpdatrekksrlvrqfhftswPdvGvPfepiGmlkllkkvkklnqqsag.pivvhcs
NGVGRSGTFCVISSVIERLKTEQVIDVFQVIKRIRVNRPGAVESLTQYVFCYQIIQKY
||||.|||.|...|.||.|.|...|||...||.| .|| | .. ||.|.|.....|
aGvGrtGtfivldavlervkaerkvdvfefvkrlrlqrpqmvqtdeqyefiykvlley
|
|||||||||
subfamily_Sponge-PTP5_pd | Subfamily Sponge-PTP5 | 629-879 | 6.4e-54 | 177.8 | In-house | 13-262 (283) | alignment | ||
Range on Protein: 629-879
Range on HMM: 13-262/283.0
NSFTSREIPAEEKSVGEEPQNLQKNRFCDIVALNSCRVMLRKEHAdeesDYINAVFLH---AHRERNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNN
. . .| . . .| .|||. .||. . || |. | |||||||. ... . .|..| || .|| |||.|| | .| .|||| .
evlkrlsvpdldadiasadenkrknrnqeivpadqwrvelksesr....dyinavfipvsksykqdkkyiiaqsPldrtvvdfWkmvfdekitaivmltk
LHE-LDQEYPQYWPDHGATKYGHIGVSVLSKQEKGDVISTKLEVTRKKVRRKTHEVRHLHHVSWpDKCIPEVACSVLDLLDDVQTSQQQCGNAPVLVQCS
| | |... |||| .|. .|| |.. . | .| . . ..| . | . | .. .. | .. |.. |.. ..|..| ||
lqedlrikCsqyWPkrGsedyGeftvtlrkettsnsfiikelllrvnssakstlllahyqvidW.leygeqaiinslvkfnkvislqteskkgPivvhCs
NGVGRSGTFCVISSVIERLKTEQVIDVFQVIKRIRVNRPGAVESLTQYVFCYQII
.|.||...|. .|. .. ..|| |.|||.|.| .|..|..|| .| || . ....
tgiGrtavfiaasasvkdaltesvvdvfavvkimreqrmmavqtldqyklvhelv
|
|||||||||
subfamily_Cele-PTP-13_pd | Subfamily Cele-PTP-13 | 633-881 | 1.3e-28 | 94.4 | In-house | 21-267 (281) | alignment | ||
Range on Protein: 633-881
Range on HMM: 21-267/281.0
SREIPAEEKSVGEEPQNLQKNRFCDIVALNSCRVMLRKE-HADEESDYINAVFLHAHRERNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHELDQ
. |.. .| ..| | .|||. .| .|. || |. . . .||| | .... . .| || | || |||||. . . .|||| .. | ..
pgdppsdlctvfnqpvnnkknrylnipcldisrvqlkvkmpnknstdyihanyirspflkrgyiltqgpkketradfwrmiwqenttaivmlcqfletnr
EY-PQYWPD--HGATKYGHIGVSVLSKQEKGDVISTKLEVTRKkvrRKTHEVRHLHHVSWPDKCIPEVACSVLDLLDDVQTSqqqcgNAPVLVQCSNGVG
| .|.| | . .. .. || . ...|.|... . .|. . | ||| .|| . .| .| ... .| ...|| |||
ekcaeyfprnahcclqfdklsvsyedstvnkslvttrlnlsye...getrlithwlwkewpdwqvpessevmlkilrkirar.....stppvihcsagvg
RSGTFCVISSVIERLKTEQ-VIDVFQVIKRIRVN-RPGAVESLTQYVFCYQIIQK
||||. . .. ... . |. |.. ..|| | .|..| ||.. ....
rsgtlmaveialqsihshftlpdikqivshlrvtgraasvqtlqqymliwkvlld
|
|||||||||
subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 634-890 | 1.3e-59 | 197.0 | In-house | 10-263 (284) | alignment | ||
Range on Protein: 634-890
Range on HMM: 10-263/284.0
REIPAEEKSVGEEPQNLQKNRFCDIVALNSCRVMLRKEHADEESDYINAVFLHAHRERNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNnlhelDQEY
. ... ... . .|| |||. .|.| . .| |.. | |||||| |. .. .. .|||| || .|..|||||. .|.. |||.| ..
lgvngtdqtfanldqnkdknrighilafdknvvklerliGeefsdyinasfitGyqrkdkyiatqGPldntladfWrmiweyncstivllt.....kdkc
PQYWPDHGATKYGHIGVSVLSKQEKGDVISTKLEVTRKKVRRKTHEVRHLHHVSWPDKCIPEVACSVLDLLDDVQ-TSQQQCGNAPVLVQCSNGVGRSGT
|||| .. |... |.| | .| . . ..|.... .. ..| | |||. |. . .. |.. |. .... ..|...| || ||||.|.
sqywplkivikeerfkvkvdsveeseeyvvrdielsedgkekdirkirqfhflgwpdvgvpdypsdlmrlvkkvrhltskenhranivvhcsagvgrtgv
FCVISSVIERLKTEQVIDVFQVIKRIRVNRPGAVESLTQYVFCYQIIQ-KYLGSFSDYA
. |. ...|.| |. .||..... .| .|. |..|.|| |.| . ..| ..|| |
yivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysalleehlfghsdva
|
|||||||||
subfamily_PTPN14_pd | Subfamily PTPN14 | 634-883 | 2.4e-43 | 143.3 | In-house | 35-296 (300) | alignment | ||
Range on Protein: 634-883
Range on HMM: 35-296/300.0
REIpAEEKSVGEEPQNLQKNRFCDIVALNSCRVMLRKEHADeESDYINAVFLHA--HRERNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHELDQ
.. . |... |.| .|||| |.. . .|| | . . ...|||| ... .. .|..| || ||.|||.|| . .. |||| . .| .
kre.dallstaklpenaeknrfkdvlPyednrvelsptken.stgyinassikvsvggkersyivaqgPleltvqdfWqmvWeqgvqlivmlteeeedgk
E-YPQYWPDH----GATKYGHIGVSVLSKQEKGDVISTKLEVTRKKvRRKTHEVRHLHHVSWPDKCIPEVACSVLDLLDDVQTSQQQ--------CGNAP
| .|.|.. ..|. |. ... . || |.|.. .. .| || .. |||. .|| . |. |..|| ... . |
eksfkyfPkleskkktvefgkfkvttkfsedsdsvittglklkhlp.skeertvwhlqytDWpdhgvPeDvkgflsyLeevqsvrrktnseveskeskPP
VLVQCSNGVGRSGTFCVISSVIERLKTEQVIDVFQVIKRIRVNRPGAVESLTQYVFCYQIIQKYL
||| ||.||||.| . .|. |.....||. .|..|.| | |..|.|| | |... |||
vlvhCsaGvGrtGvlilsdlliatlehneeidikkvlarLreqrmllvqtlaqYkfvYkvlikyl
|
|||||||||
subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 634-883 | 1.8e-37 | 123.7 | In-house | 24-277 (287) | alignment | ||
Range on Protein: 634-883
Range on HMM: 24-277/287.0
REIPAEEKSvGEEPQNLQKNRFCDIVALNSCRVMLRKEhADEESDYINAVFLHAHRERNAFIATQHPLLETVEDFWRMVTDYDIGTIVML-NNLHELDQE
. .| |. || . .|||..|.. .. ||.| .| .. |||||| .. .... .||||.| |. || ||||.| . ..... .. | ..
esstatfka.aeelaavkknryadvlPiddtrvllsae.gelGsdyinanyvasytddeafiaaqgPiaatvrdfwravletrsasvitmtreveearlk
YPQYWPDH-GATKYGHIGVSVLSKQEKGDVIST-KLEVTRKKvRRKTHEVRHLHHVSWPDKCIPEVAC----SVLDLLDDVQTSQQQCGNAPVLVQCSNG
.|||.. . | | .|... | .. | . . |... |. |. .||||| .. | ||| . .. ... . |..| .. |
cykywPerevPmrvGGysvvlldydikePeygvralrlidle.trearvvkqldllswPdkvlaPtavglirfvldvkqhielardasevGPlvvhddvG
VGRSGTFCVISSVIERLKTEQVIDVFQVIKRIRVNRPGAVESLTQYVFCYQIIQKYL
.||||.. . ...||. .|| .|. |.| | . | . |. . |. . |
iGrsGillatlvlvsrledlGrvdvaavvirlreyraalvqavvqlrllyealvtyy
|
|||||||||
subfamily_eak_pd | Subfamily eak | 634-796 | 8e-12 | 39.2 | In-house | 37-197 (332) | alignment | ||
Range on Protein: 634-796
Range on HMM: 37-197/332.0
REIPAEEKSVGEEPQNLQKNrFCDIVALNSCRVMLRKEHADeESDYINAVFLHAHRERNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHELD-QE
. .. .|... .....| .|| . | | . . |||| . . .| | . . | ||.|| . .||.| . ||. ..
dyqrllsisetarleavnrn.vvkivpydrylvrltssqln.rlGyinaslaefsevGrkyiltGiasedkvfafwqmvleqkspaivqlledvelklek
YPQYWPDHG--ATKYGHIGVSVLSKQEKGDVISTKLEVtrkKVRRKTHEVRHLHHVSWPDKCIPEV
. .|.||.. |.|.. | . ... . .||. .. .||.| | . | . .| .
sdkyfpdktreelkfGildverkefvkrniletrllel...skGnethrvlhykvfGwtettlpky
|
|||||||||
subfamily_PTPN3_pd | Subfamily PTPN3 | 635-882 | 2.8e-48 | 159.2 | In-house | 27-275 (280) | alignment | ||
Range on Protein: 635-882
Range on HMM: 27-275/280.0
EIPAEEKSVGEEPQNLQKNRFCDIVALNSCRVMLRKEhadeESDYINAVFLHAHR----ERNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHELD
| . |. |.||.|||. ||.. .. ||.|... |.||||| .. | .|||| || .|..|||.|| . .. .|||| .| |
kkpglaisaarkpenlsknryrdilpydatrvklkes....etdyinanyvnmeipstglvnryiatqGPlaktatdfWqmvweqksslivmlttlverG
-QEYPQYWPDHG-ATKYGHIGVSVLSKQEKGDVISTKLEVTRKKVRrKTHEVRHLHHVSWPDKCIPEVACSVLDLLDDVQTSQqQCGNAPVLVQCSNGVG
. ||||... ..||.. | . ...|. .. .| ...|. . . ... .| ...|||...|. . ..|.... |.. . . . ||.| || |.|
rvkChqyWPetedeleygefsvkcekedetksyvlrelvlkdketk.eerkilqlqylaWpdhgvPddsadflefvervrklr.sgkeePvvvhCsaGig
RSGTFCVISSVIERLKTEQVIDVFQVIKRIRVNRPGAVESLTQYVF-CYQIIQKY
|.| . .. . . ... . . ......| | |.. .|| | | |.. |
rtGvlilletalalieaaepvypldivrtmrdqramlvqtasqykfvCeailkvy
|
|||||||||
subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 635-881 | 6.3e-36 | 118.7 | In-house | 19-293 (297) | alignment | ||
Range on Protein: 635-881
Range on HMM: 19-293/297.0
EIPAEEKSVGEEPQNLQKNRFCDIVALNSCRVMLRKEHadEESDYINAVFLHAHRERN--AFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHELDQE
| .|. |. . |.|||. ||.| .. || |.. |.||||| .. | . .| .| || .||.|||..|.. |...|||. .| | ..
eargesfssakrnsslrknryrdilatddtrvkllrvi..terdyinadyvvfpdeeadlkyilaqGplsatvddfwtlvaeqdvrvivmvaklqedGrd
--YPqYWPD--HGATKYGHIGVSVLSKQ--EKGDVISTKLEVTRKkvrRKTHEVRHLHHVSWPDKCIP----EVA------CS-------VLDLLD----
.| |||. . | |.. | ||. | || |.|.. . .. ||| ..||||. .| .. || .| |..
kcap.ywpsvvqerlkagdvvveflsstsdefdrviltelqliyr...sesrvvrhvqflswpdhGvpsdledlvrfqaqvcscciavpmmlalvemfta
----DVQTSQQ-QCGNAPVLVQCSNGVGRSGTFCVISSVIERLKTEQVIDVFQVIKRIRVNRPGAVESLTQYVFCYQIIQK
... . . ||..|| || |||||| ....|. ... || ... .| .|. |..| |. ..|... |
mvflqleslraemprnayllvhcsaGvGrsGvvvlsdvilaklrkkripdvaailsilreqrarlvqtleqfellydavlk
|
|||||||||
subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 636-883 | 1.1e-60 | 200.1 | In-house | 31-277 (315) | alignment | ||
Range on Protein: 636-883
Range on HMM: 31-277/315.0
IPAEEKSVGEEPQNLQKNRFCDIVALNSCRVMLRKEHADEESDYINAVFLHAHRERNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHELDQ-EYP
.. .. |. |..| .|||. .|. |.| ||.| . .|||||| .... . .|.||.| || .|.|||||| .... ||||.....| |. .
PdiyrqrvaretinfkknryknilPldsarvkleviddsPdsdyinasyiksvdddkayiasqgPlkasvddfwrmvlqekvttivmvtkkqegdkikcr
QYWPD--HGATKYGHIGVSVLSKQEKGDVISTKLeVTRKKvrRKTHEVRHLHHVSWPDKCIPEVACSVLDLLDDVQTSqQQCGNAPVLVQCSNGVGRSGT
||||| ....| | |..|| . .| . || |||| ... | . |||| ... . |.| |. .|... .. . ..|| || ||||.|
qywPdrkadsvefGsikvellsleadtdgvarkl.vtrks..eesrtvtqfqftewPdkGvdkqtssllklikevkad.ngkkefsllvhcsaGvGrtGv
FCVISSVIERLKTEQVIDVFQVIKRIRVNRPGAVESLTQYVFCYQIIQKYL
.. | .|....| ....|||...| .| .|| | . .| | |......|
visidevvaqikrtrsvdvfnfvknlrakrpylvqteeeyafiydavledl
|
|||||||||
subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 636-752 | 4.3e-18 | 60.1 | In-house | 34-162 (350) | alignment | ||
Range on Protein: 636-752
Range on HMM: 34-162/350.0
IPAEEKSVGEEPQNLQKNRFCDIVALNSCRVMLR--------KEHADEESDYINAVFLHAH----RERNAF--IATQHPLLETVEDFWRMVTDYDIGTIV
| .. . | . |||. .|. . || |. |.|. . .||||| .|. . | |||| || .||.||..... .. |.
spsnDvilseGvelfaknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvil
MLNNLHELDQE-YPQYWPDHGatkYGHIGVSV
.|... ||. | . .||.. . | | | .
sltsdvelnlekcyrYWqegs...ydditvkl
|
|||||||||
subfamily_ptpA1_pd | Subfamily ptpA1 | 637-843 | 3.7e-28 | 93.4 | In-house | 35-256 (418) | alignment | ||
Range on Protein: 637-843
Range on HMM: 35-256/418.0
PAEEKSVGEEPQNLQKNRFCDIVALNSCRVMLRKEHADEESDYINAVFLHAHRErNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHE-LDQEYPQ
| | |.. .| |||. .|. .| || |.| . | |||||| .. . ||.|| || .|. |||||| . ||||. | . .
gpsetsegdkkhntsknrytnilpvnhtrvqlkkiqdkegsdyinanyidgayp.kqfictqgplpntiadfwrmvwenrcriivmlsresencrikcdr
YWPDH-GATKYGHI--GVSVLS--KQEKGDVIS-TKLEVTRKKVR----RKTHEVRHLHHVSWPDKCIPEVACSVLDLLDDVQTSQQQC-----GNAPVL
|||.. | .. | |. | .|| . |. ...| .|... . .. |||. ||. . . .|| . |.| | |..
ywpeqiggeqfsiygngnevfgtysvelveviqdpereiitrnirltfegetrditqyqyegwpdhnipdhtqpfrqllhsitnrqnqiipssdrnvpii
VQCSNGVGRSGTFCVISSVIERL
|.|| ||||.|||| ....|
vhcsagvgrtgtfctavimmkkl
|
|||||||||
subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 638-886 | 3.7e-75 | 247.9 | In-house | 35-286 (305) | alignment | ||
Range on Protein: 638-886
Range on HMM: 35-286/305.0
AEEKSVGEEPQNLQKNRFCDIVALNSCRVMLRKEHADEESDYINAVFLHAHRERNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHELDQEY-PQY
| ||.. .| .|||. .|. |. |..|.... ...|||||| ...........|..| || .||.||||.. .. . ||||| .| | ... ||
eesidvgkkeankaknrlkeitlldddriiltekeslddsdyinasyvdgykrkkkyivaqgPlkntvadfWrliveekvstivmltklveggkdkCrqY
WPDHGAT--KYGHIGVSVLSKQEKGDVISTKLEVTRKKVRRKTHEVRHLHHVSWPDKCIPEVACSVLDLLDDVQTSQQQCGNAPVLVQCSNGVGRSGTFC
||. . ..|.. | . |... | | ||... .. .... | ... .|||. .|. | |.|.|...|| .|.. . |.|| ||.||||.|.|.
WpesktekkefgefsvelksektasdyieRklkisiededkesrtvlqyqltdWPdhGvpqfatsllslikrvqkdqkkdkgvpllVhCsagvgRtGvfi
VISSVIERLKTEQVIDVFQVIKRIRVNRPGAVESLTQYVFCYQIIQKYLGSF
... .||||.|.|.|||.|.|..| .|...|..| ||||......... ..
avdialerlkkEevvdvfevlkqlRskrmkmvqtldqYvflhdaldelitcg
|
|||||||||
0045098 | (Phosphotyrosine protein) phosphatases II | 638-884 | 1.1e-64 | 213.8 | In-house | 22-273 (278) | alignment | ||
Range on Protein: 638-884
Range on HMM: 22-273/278.0
AEEKSVGEEPQNLQKNRFCDIVALNSCRVMlrkehadeesDYINAVFLHAHreRNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHEL-DQEYPQY
| ... . || |||. ||......|| ||||| ... . ...|||||.|| .||.|||||. ...| .||||..|.|| . ..||
pseitpalylgnldknRykdilpydhsrVk..........dYINAsyidgy..pkkfIatqgPlpstvadfwrmlwelgitvivmltelvelgrekcaqy
WPDHGATKYGHIGVSVLSKQEKGDVISTKLEVTRK---KVRRKTHEVRHLHHVSWPDKCIPEVA--CSVLDLLDDVQTSQQ------------QCGNAPV
||..| ||.. | .|| .. .|.. ..|.|| . ....|.||| ..||| ..|. |.|.||. .. .. . .. ||
wpeggsltygdftvtllseevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllsslllldsggpv
LVQCSNGVGRSGTFCVISSVIERLktEQVIDVFQVIKRIRVNRPG-AVESLTQYVFCYQIIQKYLG
|| || ||||.||.... ..|.| |...|.....| .| ||| ||..| ||.|.|. ....|
lVHCsaGvgRtGtlvaaylmlell..eggvdlleavkelrsqRpglavqnleqyrflyefllelll
|
|||||||||
subfamily_PTPRN_pd | Subfamily PTPRN | 638-879 | 6.3e-44 | 144.9 | In-house | 45-288 (297) | alignment | ||
Range on Protein: 638-879
Range on HMM: 45-288/297.0
AEEKSVGEEPQNLQKNRFCDIVALNSCRVMLRKEHADEESDYINAVFLHAHRERN-AFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHELDQEY-PQ
. |.|.....|..||| .... . || |..| ..|.|||||| .. | |. |.|||| || .|| |||.|| . . ||.| .|.| . . .
pstkevakaeknvkknrskavlpydhsrvklkeeasaeksdyinasaildhdprapayiatqgplastvadfwqmvweqGvvvivnltrleeegvkqckr
YWPDHGATKYGHIGVSVLSKQEKGDVISTKLEVTRKKVRRKTHEVRHLHHVSWPDKCIPEVACSVLDLLDDVQTSQQQcGNAPVLVQCSNGVGRSGTFCV
||||.|. |. | ..|. | . . ..| | .|..|||.. .| | |.|.. |. | . .|..| ||.|.||.|....
ywpdeGsevyhiyevhlvsehiwcddylvrsfylknlqtsetrtvtqfhflswpeegvPasaksllefrrkvnksyrG.rscpivvhcsdGaGrtGvyil
ISSVIERL-KTEQVIDVFQVIKRIRVNRPGAVESLTQYVFCYQII
| |..|| | . ||. .. .| .||| |.. |. |... .
idlvlnrllkGvkeidiaatlehlrdqrpglvktkdqfefaltav
|
|||||||||
subfamily_Urchin-PTP-4_pd | Subfamily Urchin-PTP-4 | 638-879 | 6.1e-42 | 138.4 | In-house | 34-232 (392) | alignment | ||
Range on Protein: 638-879
Range on HMM: 34-232/392.0
AEEKSVGEEPQNLQKNRFCDIVALNSCRVMLRKEHADEESDYINAVFLHAHRERNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHELDqeypqyw
. ...|.... ||.|||. .|. ..| ||.| .|||.|| .... .|.||.| | ...|||||| . .. ||.|...|.| |
iypqtvaqkeinlkknryknilpydsarvkleviddipdsdylnasyipsfdnekayiasqgpnaaslddfwrmvfqenvttiamvtklkegd.......
pdhgatkyghigvsvlskqekgdvistklevtrkkVRRKTHEVRHLHHVSWPDKCIPEVACSVLDLLDDVQTSQQQCGnAPVLVQCSNGVGRSGTFCVIS
... | | . |||| .|. ..|.| .. .|.. | |....|| ||||.| |
...................................kgddartvaqfhftewPdkdvpkhtssllkfikevkadfGqyt.hpliihcsagvgrtgvvisid
SVIERLKTEQVIDVFQVIKRIRVNRPGAVESLTQYVFCYQII
||. . |. ...|||... || .|| |.. || | | .
svvahakktrmvdvfnfvtnirrkrpymvqtkeqyafiygav
|
|||||||||
subfamily_Sponge-PTP9_pd | Subfamily Sponge-PTP9 | 639-891 | 1.5e-55 | 183.0 | In-house | 30-301 (301) | alignment | ||
Range on Protein: 639-891
Range on HMM: 30-301/301.0
EEKSVGEEPQNLQKNRFCDIVALNSCRVMLRKEHA--DEESDYINAVFLHAHRERNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHEL-DQEYPQ
.. .|| . .| . ||| .|. .. |..|..... . .|||| .... .|...|||.| |. .|. ||||.. .. .|||. ||.| .. |
ksctvglseenkalnrfknitvyddnriilkpkpnldlcqreyinasyidgysekkkfiaaqgpmkktlvdfWrliwqekpvsivmvtnlkegtkskceq
YWPDHGATKY--GHIGVSVLSKQEKGDVISTKLEVTRK--------------KVRRKTHEVRHLHHVSWPDKCIPEVACSVLDLLDDVQTSQQQCGNAPV
|||. |... |.. | . ..| | . .| |. . | ......| |. ..||. . || .||| ||. | .||
ywpnseaeseefgpftvtlvneqvyPdfvirqlnvkiqdgsnngyierkfkvksdksswdvlqlqvtdWpqdGvvreprtvLqviddvihrqqkigggpv
LVQCSNGVGRSGTFCVISSVIERLKTEQVIDVFQVIKRIRVNRPGAVESLTQYVFCYQIIQKYLGSFSDYAN
.| ||..|.|||..| .| .| | | |.|||||.|..| ..|||| | ||.. |..|..|| | |||
vVHCSdtVsrsGvYcsvsiglEQckaegVVdvfqvtkavrrskpgaVtTLeqytsiydvidmylqlnstyan
|
|||||||||
subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 639-883 | 2e-50 | 166.3 | In-house | 10-264 (270) | alignment | ||
Range on Protein: 639-883
Range on HMM: 10-264/270.0
EEKSVGEEPQNLQKNRFCDIVALNSCRVMLRKEHADEESDYINAVFLH-AHRERNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHELDQEY-PQY
.|... | .. . ||. ||. ||.| ... |... |||| ... .. |....||.. || |...||||. . .|||. .|.| .. .|
sesdlpeaargkklnRyadiLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerY
WPDHGA----TKYGHIGVSVLSKQEKGDVISTKLEVTRKKvrrKTHEVRHLHHVSWPDKCIPEVAC------SVLDLLDDVQTSQQQCGNA-PVLVQCSN
|| . ...|.| | .||.. . | |.|....| ..... | ....|||. .|. . ..| .| .|. |... .| |.|| ||.
Wpaepkekvkledgkikvlalseekeegyiltrlrleekg...eerrlvHfwyntWpdhgvpreedsslstdqllkmlravrrsekeldkaePllvHcsa
GVGRSGTFCVISSVIERLKTEQVIDVFQVIKRIRVNRPGAVESLTQYVFCYQIIQKYL
||||.||. .. ... |.... .|| ..|...| .|. |. || | |. ...|
GvgRtGtlialDiavrlLeetkkvdvlaiieelRkdRmalvqhpeqyeflykavveya
|
|||||||||
subfamily_PTPN1_pd | Subfamily PTPN1 | 640-879 | 1.8e-43 | 143.3 | In-house | 23-267 (290) | alignment | ||
Range on Protein: 640-879
Range on HMM: 23-267/290.0
EKSVGEEPQNLQKNRFCDIVALNSCRVMLRKEHAdeesDYINAVFLHAHRERNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHELDQE-YPQYWP
. .. ..|.| ..||. |. . .|..|.... ||||| ...... . .| || || .||. ||.|| . . ..||||.. | .| ||||
ptreaklpenrnlnryrdvspydhsrikleradn....dyinaslveleeakrsyiltqGPlpntvdhfWqmvWeqkskavvmlnkvvekeqikcaqywP
DHG---ATKYG--HIGVSVLSKQEKGDVISTKLEVTRKKVrRKTHEVRHLHHVSWPDKCIPEVACSVLDLLDDVQTSQQQC-GNAPVLVQCSNGVGRSGT
. . .. .. | ..|...| . .||.. .| ..|.|. | |...||| .|| . |..| .|. | |... || |.|||||
qgeeekellledtklkvkliseerksyytvrllelenlkt.qetreilhfhyttwpdfgvpespaaflkflfkvresGslssdvGpavihcsaGiGrsGt
FCVISSVIERLKTE---QVIDVFQVIKRIRVNRPGAVESLTQYVFCYQII
||.. ... ... . . .|. .|. .| | | . | | |. |
fclvdtclvliekkddlssvdikkvllelrkyrlGliqtadqlrfsylai
|
|||||||||
subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 640-739 | 8.2e-09 | 29.2 | In-house | 39-155 (349) | alignment | ||
Range on Protein: 640-739
Range on HMM: 39-155/349.0
EKSVGEEPQNLQKNRFCDIVALNSCRVMLRKE--------HADEE------SDYINAVFLHAHRE--RNAFIATQHPLLETVEDFWRMVTDYDIGTIVML
. . | . |||. ||. . ||.|.| .. | ||||| .|. | . .|||| || ||.||..... . .. |
dvilseGvelfaknrykdilPyehsrvklkkslksskvikastsesdsgklddyinanylkltrisvekkyiatqaPlPstvddfykvillngvklvlsL
NNLHELDQEY-PQYWPD
|. .||. | .|| .
nddkelslekcdiywqe
|
|||||||||
subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 641-891 | 8.4e-125 | 410.0 | In-house | 1-250 (250) | alignment | ||
Range on Protein: 641-891
Range on HMM: 1-250/250.0
KSVGEEPQNLQKNRFCDIVALNSCRVMLRKEHADEESDYINAVFLHAHRERNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHELDQEYPQYWPDH
|||...|||..|||. ||.||.|.||.| ||..|.|||||||.|||...||.||||||.|| .|.|||||||.....||||||.||.| ...|.||||
ksvakkpqnkeknryadiialdssrvvLekekgdkesdyinasflhgyderkafiatqgPlqatiedfWrmvleeksgtivmLtnLkesektyhqywPve
GATKYGHIGVSVLSKQEKGDVISTKLEVTRKKvRRKTHEVRHLHHVSWPDKCIPEVACSVLDLLDDVQTSQQQCGNAPVLVQCSNGVGRSGTFCVISSVI
.|.|||.. ||.|||.|..|....|| ....| . . ||.||.|.||||..|||| .||.||..||.||||.|||||.||||.||||||.|..|..|.
kaekyGdvtvsllskeefadytkrklklskak.kaderivrqlhfvvWPdkgvPevatavLellkkvqasqqqagnaPvivqCsaGvgrsGafiaidavl
ERLKTEQVIDVFQVIKRIRVNRPGAVESLTQYVFCYQIIQKYLGSFSDYAN
||||.|.|.|||.|||..| .||.|||||.||||.|.||.|.| |..|||.
erlkkekvvdvfkvikvlrkdrphavesleqyvfvyeiilkaldsvedyar
|
|||||||||
subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 641-885 | 2.6e-65 | 215.5 | In-house | 43-286 (297) | alignment | ||
Range on Protein: 641-885
Range on HMM: 43-286/297.0
KSVGEEPQNLQKNRFCDIVALNSCRVMLRKEHADEESDYINAVFLHAHRErnAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHELDQEYPQYWPDH
. | |. |..|.|. .|. .| ||.|. | .|||.|| |... .. .|.|| | .||.|||.|| |... ||||||...| |.. .||.|.
qtvaekkvnfeksRYkniLPydssRvkLaivnddpdsDyvnasfvkgnkh..rlittqmPmkatvadfWamvldeqvstivmlnddnerdkkcaryWsdk
GATKYGHIGVSVLSKQEKGDVISTKLEVTRKKVrRKTHEVRHLHHVSWPDKCIPE--VACSVLDLLDDVQTSQQQCGNAPVLVQCSNGVGRSGTFCVISS
| |..|.. | .|| .|. | .||||. | .... |. ..|.|||| ... | |.|.|...|. . .| ..|.|| |..|||| | .. | |
gvttfGdvsvvllsvsereGfikrelevtkgka.karrvvkqyqfveWPdkaverkdsassllklisevrkdfsqnaegPllvhclaGvGrtgvlltids
VIERLKTEQVIDVFQVIKRIRVNRPGAVESLTQYVFCYQIIQKYLGS
|. . | |. .|.|...|..| .|| | || | |... ..| |
vvaeakrekevdifglvkklrqerpylvqtkeqykfvyvavlealls
|
|||||||||
subfamily_PTPN9_pd | Subfamily PTPN9 | 641-882 | 4.5e-58 | 191.6 | In-house | 34-289 (297) | alignment | ||
Range on Protein: 641-882
Range on HMM: 34-289/297.0
KSVGEEPQNLQKNRFCDIVALNSCRVMLRKEHADEESDYINAVFLHAHRERNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHELDQ-EYPQYWP-
. . . ||.|||. |.. ... ||.| |.. ||.|||||| |. .....|||||| || .||.|||||| . .. .||| . | . ||||
flasklranleknrytdvlcydetrvvlakvdedeasdyinanfvdGykqkkafiatqGplkktvsdfWrmvWeqevlvivmttrvvergrlkcgqyWpl
-DHGATKYGHIGVSVLSKQEKGDVISTKLEVTRKKVrRKTHEVRHLHHVSWPDKCIPEVACSVLDLLDDVQTSQQ------------QCGNAPVLVQCSN
.. ....|.. ||... .|. | ..||... | ... .| | .|||| .|. | |.||.|. |. | .. . |..| ||
eeessaefgdlsvsnveveeeedykvrvleiknvkt.eesrkvthfqflsWPdyGvPssaaslldvlekvrekqalavkelgdewkghpsgPPivvhcsa
GVGRSGTFCVISSVIERLKTEQVIDVFQVIKRIRVNRPGAVESLTQYVFCYQIIQKY
|.||.|||. . ..||......||....|..| | .. ||.|||. . |
GiGrtGtfitldiclsrleevgtvdvvetvkllrtqrafsiqtpeqyefcylavley
|
|||||||||
subfamily_Sponge-PTP3_pd | Subfamily Sponge-PTP3 | 641-698 | 2.6e-08 | 27.9 | In-house | 40-94 (95) | alignment | ||
Range on Protein: 641-698
Range on HMM: 40-94/95.0
KSVGEEPQNLQKNRFCDIVALNSCRVMLRKEhadEESDYINAVFLHAHRERNAFIATQ
.|| |. |||| .|. .. ||.| .||||||.|. . .|..||.|
ytvgsseanipknrflnifpydatrvvlttk...rdsdyinacfvdgyarkncyiaaq
|
|||||||||
0040439 | (Phosphotyrosine protein) phosphatases II | 642-883 | 4e-68 | 225.0 | In-house | 4-246 (249) | alignment | ||
Range on Protein: 642-883
Range on HMM: 4-246/249.0
SVGEEPQNLQKNRFCDIVALNSCRVMLRKEHADEESDYINAVFLHAHRERNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHEL-DQEYPQYWPDH
||.. | |. |||. ||......|| | . |||||| ... . ..|||||.|| |||||||||. ...|..||||..| || . . ||||.
svallpenkdknrypdilpydhsrvklsilpglflsdyinAsyidgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqywplg
GATKYGHIGVSVLSKQEKGDVISTKLEVTRKkVRRKTHEVRHLHHVSWPDKCIPEVACSVLDLLDDVQTSQQQC-GNAPVLVQCSNGVGRSGTFCVISSV
| ..||.. | .|| ..|.|.. ..||.|.. ....|.|.....||| .|. ..||... |.. .... . |||| ||.||||.|||... .
gsleygdftvtllsvevkddytvrtleltnl.ydgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtfiaaylm
IERLKTEQVIDVFQVIKRIRVNRPGAVESLTQYVFCYQIIQKYL
.|.|..|. .|.....| .| |||||... ||.|.|......|
leqlekelgvdleeavkllrsqRpgavqnpeqyrflyeallell
|
|||||||||
0042113 | (Phosphotyrosine protein) phosphatases II | 642-883 | 8.5e-68 | 223.7 | In-house | 2-243 (245) | alignment | ||
Range on Protein: 642-883
Range on HMM: 2-243/245.0
SVGEEPQNLQKNRFCDIVALNSCRVMLRKEHADEESDYINAVFLHAHRERNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHELDQE-YPQYWPDH
||.. | | .|||. ||......|| | . |. |||||| . . .| . |||||.|| |||||||||. ...| |||||....||... ..||||..
svallpenkdknrysdilpydhtrvklspdggdldsdyinasyvdgyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywplg
GATKYGHIGVSVLSKQEKGDVISTKLEVTRkKVRRKTHEVRHLHHVSWPDKCIPEVACSVLDLLDDVQTSQQQCGNAPVLVQCSNGVGRSGTFCVISSVI
. ..||.. | .|| . ..|.. ..||||. . ...||.|.|...||| ..|. ..||.|. |.. .....| |||| || ||||.|||... ..
esltygdftvtllseehlddytvrtlevtn.lgddesrevihyhylpwpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylml
ERLKTEQVIDVFQVIKRIRVNRPGAVESLTQYVFCYQIIQKYL
|.|..|. .......|..| |||||... ||.|.|......|
eqlekelgvsleeavkelrsqRpgavqtpsqyrflyeallell
|
|||||||||
subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 642-883 | 9.9e-59 | 193.8 | In-house | 36-276 (515) | alignment | ||
Range on Protein: 642-883
Range on HMM: 36-276/515.0
SVGEEPQNLQKNRFCDIVALNSCRVMLRKEHADEESDYINAVFLHAHRERNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHELDQE-YPQYWPD-
.| .| | .|||. .|. ..| || | . . .|||.|| .... .|.||.| |. .|.||||.| .... ||.|...|.| |. .||||
tvaqeeinfkknryknilPydsvrvklevindnPhsdyfnasyipsfdndkayiasqgPnkasvddfWrlvlqenvttiamvtklkegdkikcgkyWPdk
-HGATKYGHIGVSVLSKQEKGDVISTKLEVTRKKvrrKTHEVRHLHHVSWPDKCIPEVACSVLDLLDDVQTSQQQCGnAPVLVQCSNGVGRSGTFCVISS
. |.|.| |...| . .. | ||.|.. . ... | | |||| .|. . |.| |. .|.....| |... || |||| | .. | |
pgdsvkfGsikvelvsleactggikrkltvlkgd...dsrtvtqfhfteWPdkGvpkhtssllklikevkadhgqyt.hpliihcsaGvGrtGvvisids
VIERLKTEQVIDVFQVIKRIRVNRPGAVESLTQYVFCYQIIQKYL
|. . || ...|||.... || .|| | || | |.... .|
vvahakttrmvdvfnfvtnirqkrpylvqtqeqyafiygavledl
|
|||||||||
subfamily_PTPRK_pd | Subfamily PTPRK | 643-879 | 2.2e-69 | 228.7 | In-house | 37-273 (314) | alignment | ||
Range on Protein: 643-879
Range on HMM: 37-273/314.0
VGEEPQNLQKNRFCDIVALNSCRVMLRKEHADEESDYINAVFLHAHRERNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHELD-QEYPQYWPDHG
. . .| .|||. ||.| . .||.| . | .|||||| .. ... .|||.||.|| |||.||||.| |.. .||||..| | . .|||...
aakkdenreknrsgdilaydrsrvflitidgdpssdyinaalidsykrpaafivtqgPlqetvkdfWrlvydencasivmltelvevgrvkClkyWPedt
ATkYGHIGVSVLSKQEKGDVISTKLEVTR-KKVRRKTHEVRHLHHVSWPDKCIPEVACSVLDLLDDVQTSQQQcGNAPVLVQCSNGVGRSGTFCVISSVI
. ||.| | ... . . .... . |.. .. ...|||......||| .| | ..|.|. |..||.. .. ...| ||.| ||.|||..|..|.
ev.ygdikvelvetellaelvvrifrveklargqeeirevrqfqflgWpdhdvPvsatgllklvrrvkksqee.eaGrivvhCsaGaGrtGtfiaidivl
ERLKTEQVIDVFQVIKRIRVNRPGAVESLTQYVFCYQII
. ...|.|.|||...| .| ... || ||.|.|..|
dmieregvvdvfnavktlrsrkvnmveteeqykfiydvi
|
|||||||||
subfamily_Cele-PTP-18_pd | Subfamily Cele-PTP-18 | 643-883 | 9.9e-31 | 101.6 | In-house | 42-287 (305) | alignment | ||
Range on Protein: 643-883
Range on HMM: 42-287/305.0
VGEEPQNLQKNRFCDIVALNSCRVMLrkeHADEESDYINAVFLHAHRERNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHELD-QEYPQYWPDH-
| |. .|||. |. |. || | .. .|| | .. . . . || || || .| ||| | . . .| || || | . .|.. .
afkeaqeagknrykdvgcldnnrvkl...egpwpheyihanyvstptnpkrfictqaplektcadfwymclqdkveaifmlcnllekgakkcleyfaskd
-GATKYGHIGVSVLSKQEKGDVIS----TKLEVTR-----KKVRRKTHEVRHLHHVSWPDKCIPEVACSVLDLLDDVQTSQqqcgnAPVLVQCSNGVGRS
.. | . | | .. .| .||. . |.. | | | . |||. .| ..|.|| . ..|. |. | || |.||.
kdvlefeekgqkisvkfessvtlkfrkdakakvtetvlviegpgekarkvthyhwidwpdrgvpaadlailellekarpsk.....gpivvhcsagigrt
GTFCVISSVIERLKTEQVID-VFQVIKRIRVNRPGAVESLTQYVFCYQIIQKYL
|. .. ....| . |.|. .....|| .| .... .||.| .|.| .|.
gsvvmleyildqllagqiiedtdkilqkireqrnnsiqtdaqylfvhqvilnyf
|
|||||||||
subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 644-879 | 5.7e-63 | 207.7 | In-house | 44-275 (315) | alignment | ||
Range on Protein: 644-879
Range on HMM: 44-275/315.0
GEEPQNLQKNRFCDIVALNSCRVMLRKEHADEESDYINAVFLHAHRERNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHELDQEYPQ-YWPDHgA
. .| ||||. .|.| . || | |..|||.|| |. . .. .||.| |. ..|.||||.| ..|||.||||.|| | ... . ||||.
akkienkqknryiniiaydksrvqlpllendphsdyvnanfidGynkkrryiaaqgpnvasvkdfwrlvfeedigkivmltnlvegekrkaekywpdk.k
TKYGHIGVSVLSKQEKGDVISTKLEVTRKkvrRKTHEVRHLHHVSWPDKCIPEVACSVLDLLDDVQTSQQQCGnAPVLVQCSNGVGRSGTFCVISSVIER
||.| |. |.. . .. | |. . . .|| ||. |||| .|. . ....| |. ... ....| ||.||||.|||. ...|...
viyGkitvtrkseevnteytvrtlsvvfg...dnirevvqlhytswpdmgvpkytiplmnlirtvkqhhtnsv.gaivvhcsaGvGrtGtfitldavldq
LKTEQVIDVFQVIKRIRVNRPGAVESLTQYVFCYQII
...|..|||...|...| || ..|... || | |...
aeaenaidvynfitgvrqnrikmvqvaeqyqfiydal
|
|||||||||
0037934 | (Phosphotyrosine protein) phosphatases II | 644-883 | 5.9e-61 | 201.4 | In-house | 5-242 (243) | alignment | ||
Range on Protein: 644-883
Range on HMM: 5-242/243.0
GEEPQNLQKNRFCDIVALNSCRVMLrkehadEESDYINAVFLHAHrERnaFIATQHPLLETVED----FWRMVTDYDIGTIVMLNNLHEL-DQEYPQYWP
. |.|| |||..||.... || | | |||||| . .| .||||.|| ||||| ||||. ...|..||||..| || . ..||||
allpenlsknrysdilpydhsrvkl......egsdyinanliyvt.pr..liatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqywp
dhGATKYGHIGVSVLSKQEKGDVISTKLEVTRKKVRRKTHEVRHLHHVSWPDKCIPEVACSVLDLLDDVQTSQQQ-------CGNAPVLVQCSNGVGRSG
| . ||.. | .|| ....|.. ..|...... |..|.|.|...||| ..|. ..||.||.|.. ... .. |||| || ||||.|
..gevtygdftvtllseehlddytvrtlllenldlddltrlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgRtG
TFCVISSVIERLkteQvIDVFQVIKRIRVNRPG-AVESLTQYVFCYQIIQKYL
|.... ....| . .|.....|..| ||| ||... ||.|.|......|
tliaaylmllll...g.vdleeavkllreqRpgkavqtpsqyrflyeallell
|
|||||||||
subfamily_Cele-PTP-17_pd | Subfamily Cele-PTP-17 | 645-722 | 8.7e-11 | 35.9 | In-house | 33-115 (347) | alignment | ||
Range on Protein: 645-722
Range on HMM: 33-115/347.0
EEPQNLQKNRFCDIVALNSCRVMLRKE-----HADEESDYINAVFLHAHRERNAFIATQHPLLETVEDFWRMVTDYDIGTIVM
| ..|.||| | .. ||.| | .||. |||| .. .. .| ||.|| .|| |||.||. . .|
ewekslsknrskdvklidatrvvlspeksknsraddvetyinashikfdnaskeyiltqyplpdtvrdfwkmvsvtkvtqvvt
|
|||||||||
subfamily_egg_pd | Subfamily egg | 646-882 | 1.9e-25 | 84.2 | In-house | 37-269 (307) | alignment | ||
Range on Protein: 646-882
Range on HMM: 37-269/307.0
EPQNLQKNRFCDIVALNSCRVMLRKEHADEESDYINAVFLHAHRERNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHELdQEYPQYWPDHGA--T
. ||.| | . .|.|| |. .. |.| | .. . | || .| || .||.|||||| .. ||||. | .. . ||| .
sdnnlekarskrvhckdssrvklelrrGqylddfihanrvkGkpllnefilaqaplkntvddfwrmvfqeevqyivmltsrkes.erceyywpkaesdsl
K--YGHIGVSVLSKQEKGDVIstkLEVTRKKVRRKTHEVRHLHHVSWPDKCIPEVAcSVLDLLDDVQTSqqqcgNAPVLVQCSNGVGRSGTFCVISSVIE
. | . . | ..| | . . ||. |. .| |.| | . . .| | | .| .. ||.||. .|| ...|. | .
vtvpGslrienlkvdskadpl...frvtklklvGgddeerflehwqgdvnnssdvy.splrvlrklrnl.....skpvvvqdilGvskaatlvaieiall
RLKTEQV--IDVFQVIKRIRVNRPGAVESLTQYVFCYQIIQKY
| . | . .. .| .|. .||| .|.| |... .
sllrGpitkslvlravvflrlrrrlsvesvllylfvyrlvlff
|
|||||||||
subfamily_PTPN5_RR_pd | Subfamily PTPN5_RR | 647-884 | 3.9e-56 | 185.1 | In-house | 26-269 (274) | alignment | ||
Range on Protein: 647-884
Range on HMM: 26-269/274.0
PQNLQKNRFCDIVALNSCRVMLRKEHADEE-SDYINAVFLHAH-RERNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHELDQ-EYPQYWPDHGAT
. . .|||...|. . ||.|..|....| |.|||| ... .| .|..||| || .||.|||||. .. |||| .|.| .. .|.||. .
fgsqtknryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntvadfWrmiyqeevqvivmltklkeaneqkCavyfPdaedy
----KYGHIGVSVLSKQEKGDVISTKLEVTRKKVrrkTHEVRHLHHVSWPDKCIPEVACSVLDLLDDVQTSQQQCGN--APVLVQCSNGVGRSGTFCVIS
.||.. . | .. |. | .|| . . ...| | . .|||. |. | ..|||...|..|... . |||.| || |.|| | | ||
eiserygdveikvekiverndysvrklvlkyler...ersvkhywytdWPdhksPddantlldlvleveesreeenaklapvvvhCsaGiGrtGcfiais
SVIERLKTEQVIDVFQVIKRIRVNRPGAVESLTQYVFCYQIIQKYLG
. .|. |.|.||.... .|..| | |.. || . .... .||
iavrqlreeivvdvlkivcnlrldrGGmvqtseqyelihralclylk
|
|||||||||
subfamily_Cele-PTP-8_pd | Subfamily Cele-PTP-8 | 647-883 | 2.9e-36 | 120.0 | In-house | 41-271 (288) | alignment | ||
Range on Protein: 647-883
Range on HMM: 41-271/288.0
PQNLQKNRFCDIVALNSCRVMLRkehaDEESDYINAVFLHAHRERNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHELDQEY-PQYWPDHG--AT
.| ..|. .. . .|| | |. ||.| . ... .. .| .| || |.| .|.|. . |. ||||..| |. .| .|.| . ..
ianptrdryenlprcditrvkls....ddpdfyiaanvvssakykrrlicaqaPlngtieelWkmllesdveyivmlcellekGkeksaeyfPsklGeka
KYGHIgvSVLSKQEKgDVISTKLEVTRKKVRRKTHE---VRHLHHVSWPDKCIPEVACSVLDLLDDVqtsqqQCGNAPVLVQCSNGVGRSGTFCVISSVI
..|.. |... . | ..|. .. ....| |..|| |.|...|| | | ||. . . . |..|..|.||||.||. .| ..
rigrl..ctvvkkkr.adidklvkvsllriskegeekvivkilhlleWdddgvPenylsplrllevl.....kslqkPivvhssaGvGrtgtlililial
ERLKTEQVIDVFQVIKRIRVNRPGAVESLTQYVFCYQIIQKYL
| |. . . . ..... | .| |... ||.. .... ..|
eslrlddflgirsllaklreerfkaiqtemqylyvhrcvleel
|
|||||||||
subfamily_Cele-PTP-6_pd | Subfamily Cele-PTP-6 | 647-883 | 1.4e-34 | 114.5 | In-house | 39-277 (307) | alignment | ||
Range on Protein: 647-883
Range on HMM: 39-277/307.0
PQNLQKNRFCDIVALNSCRVMLRKEHAdeESDYINAVFLHAHRERNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHELDQ-EYPQYWPDHGATK-
| .|||. |. . . .|.... . . |||| | .| . . ||..| || .|. .|| |. . .. ...|| .. || . |||| |
santdknryqdvkcqdkgrivvkfdgl..asdyihanylgiaikpkkficaqgplentqysfwamaiqekvesvimlckvielakikceqywpleegqkl
-YGHIG----VSVLSKQEKgDVISTKLEVTRKKV--RRKTHEVRHLHHVSWPDKCIPEVACSVLDLLDDVQTSQqqcgnAPVLVQCSNGVGRSGTFCVIS
.|. . |. | .. ..|| || .|. ..|| |||. .|.. . ..||. |. . ||.| || ||||||| ||
vfgeapntisvanlgakkl.apdedlinvttlkvdwaqksrtiqhlqwenwpdrgvpqinltainlleavrydt.....npvvvhcsaGvGrsGtivais
SVIERL-KTEQVIDVFQVIKRIRVNRPGAVESLTQYVFCYQIIQKYL
| ... . . |. .... .| .|. |... ||.. .... .|.
lvqdkmiaGinckdmkklveelrsqrhyaiqteaqylylhrvlleyf
|
|||||||||
subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 648-882 | 5.5e-46 | 151.7 | In-house | 32-258 (267) | alignment | ||
Range on Protein: 648-882
Range on HMM: 32-258/267.0
QNLQKNRFCDIVALNSCRVMLRKEHADeesdYINAVFLHAHRERNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHEldQEYPQYWPDH--GATKY
.| ..||. | . . ||.||.. . |||| ...... .||||.|| || |. ||. ...|... .||.| . . .. ...|| . | ||
knqernrlddnlpyddtrvilrtkeee....yinasyvegyktknafivtqdplkntitdfltvihdqkvpvivlltkvft..dnirlfwPPkmgqakky
GHIGVSVLSKQEKGDVISTKLEVTRKKvrRKTHEVRHLHHVSWPDKCipEVACSVLDLLDDVQTSQQQCGNAPVLVQCSNGVGRSGTFCVISSVIERLKT
. | ..|. | ||. |. .|.| .. | . . . |. . | . || |..|.||.|||||||| || | .||.||
qdltvehslekeendyqiitlelkfkn..esahnvtlyyykkwnint..nnkpylkplfgilaknqlengnrPlvvacsdGvGrsGtflvidsqlerakt
EQVIDVFQVIKRIRVNRPGAVESLTQYVFCYQIIQKY
|.| |.|. ...|| |.| |... .|....... .|
egvsdifdflrkirsqriglvdtkeryiyihellaey
|
|||||||||
subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 648-879 | 5.2e-41 | 135.4 | In-house | 2-235 (237) | alignment | ||
Range on Protein: 648-879
Range on HMM: 2-235/237.0
QNLQKNRFCDIVALNSCRVMLRKEHADeeSDYINAVFLHAHR-ERNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHELDQE-YPQYWPDHG-ATK
.| |||. .||| . .||.|. .. |||||| .|. . .||.| || . .|||.|| . |||| | | ... .|||. .
enkiknrygnivaydhsrvvlkgagsg..sdyinatylkgfdgtpkkyiaaqgplesscddfwqmvwqekcsvivmltgliegnelkchkywpstdqpaa
YGHIGVSVLSKQEKGDVISTKLEVTRKKVRRKTHEVRHLHHVSWPDKCIPEVACSVLDLLDDVQ-TSQQQCGNAPVLVQCSNGVGRSGTFCVISSVIERL
|| . ||. |.| | | .... .. . . ||||. .|. ....| . .. |. .| .. || ||||.| | || ... .
ygvltvslkkkeefsdytvrslllskrltlkevrlihqyqftswpdrgvpqqtaallrfrkniinrsphvsesgpwiihcsagvgrtgiflvidamlrqa
KTEQVIDVFQVIKRIRVNRPGAVESLTQYVFCYQII
| ..|.|... .. | .|| ... |||| .| |
kekkvvdiynyvysieedrpyiiqtkdqyvfihqti
|
|||||||||
subfamily_Cele-PTP-10_pd | Subfamily Cele-PTP-10 | 648-883 | 1.6e-28 | 94.2 | In-house | 54-289 (305) | alignment | ||
Range on Protein: 648-883
Range on HMM: 54-289/305.0
QNLQKNRFCDIVALNSCRVMLRKEHadeESDYINAVFLHAHR-ERNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHELDQ-EYPQYWPDHGATKY
. |||. |. . . | | | |||| | .. . . ||..| || .|...|| || . . |||| . || . |||| |
iaitknryqdvpcqdqsavkldkps...psdyihanyvgcpmipekrficaqgpldqtidefwwmviqnkveqivmlcktvelgklkcaqywpaaqgekl
GHI-GV--SVLSKQeKGDVISTKLEVTRKKVR---RKTHEVRHLHHVSWPDKCIPEVACSVLDLLDDVQTSQqqcgnAPVLVQCSNGVGRSGTFCVISSV
|. .| | .....| .. .. ||||. |||. .| . . |.|| .. |. |..|.|| |.||.|| | .
elksgivvenvsgs.kpmerdaeiqitllnltysgdqkmsvrhlqwtewpdrgvppckltslellsairgsk.....vpivvhcsagigrtgtivaieyi
IERLKTE-QVIDVFQVIKRIRVNRPGAVESLTQYVFCYQIIQKYL
.|.. . .. . ...| .| .| .... ||.| .... .|.
lekiaenkpcppmpelvkalrdqrafsiqndvqylfihrvmlnyf
|
|||||||||
subfamily_Cele-PTP-14_pd | Subfamily Cele-PTP-14 | 648-877 | 6.6e-27 | 88.9 | In-house | 51-284 (310) | alignment | ||
Range on Protein: 648-877
Range on HMM: 51-284/310.0
QNLQKNRFCDIVALNSCRVMLRKEHADeESDYINAVFLHAHRERNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHELDQEY-PQYWPDHGATK-Y
....|||..|.| |...|| |. ... ||| | .... |..|| .| || |. |||||. . .|..| . | . ||| | |. |
kymhknrysdvvcldtsrvklkidksr.yedyihanyvktnylrstficsqgplqhtiidfwrmifqeraesilllckvgeegrpkcvgywpslgvtety
GHIGVSVLSKQEKGD-V-------ISTKLEVTRKKVRRKTHEVRHLHHVSWPDKCIPEVACSVLDllddvQTSQQQCGNAPVLVQCSNGVGRSGTFCVIS
| | |. ||. . . . .. | . | | .. |||. .|. | . | | |..|.|| |..| .. . .
gcirvtnlsesseefeicnlavtfvpdnvpvdeqpanlkelrvslikwpnwpdrgvpdekchtvp.....qrllaqvrhgpcvvhcsagkdrlyvvvalk
SVIERLKTEQVIDVFQVIKRIRVNRPGAVESLTQYVFCYQ
|..|. . .|. .|. .. .| ... ||.. .
lkidkldrglkvdaeevktellksraiciqtelqyliidr
|
|||||||||
subfamily_Cele-PTP-4_pd | Subfamily Cele-PTP-4 | 648-882 | 2.2e-24 | 80.4 | In-house | 50-284 (302) | alignment | ||
Range on Protein: 648-882
Range on HMM: 50-284/302.0
QNLQKNRFCDIVALNSCRVMLRKehadEESDYINAVFLHAHRERNAFIATQHPLLETV---EDFWRMVTDYDIGTIVMLNNLHELDQEYPQYWP-DHGA-
.||.||. |. .|.| .| | . |. .|.|| .. .. | .| | .... |.||||| . | ..|.| ||.. ...| |.
knlkknqsedvpildsnlvklea....epdsyvnaskvevPeltrsiilaQlpkvdsedsveeFWrmvfqekivsvvilvgeeelkktlselfpkksgdy
TKYGHIGVSVLSKQ-EKGDVISTKLEVTRKKVRRKT-HEVRHlhHVSWPDKCIPEVACSVLDLLDDVqTSQQQCGNAPVLVQCSNGVGRSGTFCVISSVI
..||.. | . . .... .|| . . .| . . |..| .|. .. .| ... ....... ||.|| |.| . ..
keygkmfvNnrkVekaeeektryviEvlPegcsnsvlanvyv..ltnWkqkkvpvkyaeliktaakv.fakkikadentvivSknGaGRagafltlavav
ERLKTEQVIDVFQVIKRIRVNRPGAVESLTQYVFCYQIIQKY
|.|.... . ...| || .|| ||.||.|||. | .. |
eklqkgkepnikeivksiRsqRpravdslkQyvslyiallly
|
|||||||||
subfamily_Cele-PTP-16_pd | Subfamily Cele-PTP-16 | 648-882 | 2.1e-19 | 64.3 | In-house | 46-278 (303) | alignment | ||
Range on Protein: 648-882
Range on HMM: 46-278/303.0
QNLQKNRFCDIVALNSCRVMLrkehadEESDYINAVFLHAHRERNAfIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHELDQE-----YPQYwPDHGA
.|..||||.|.. |. .| | .| || | .|. . ...| | || || | |||.|. . . ...| | |. .|. |
knmdknrfvdvicldhskvkl......sdssyihasyleldsskka.iltqlplshtaadfwqmiieqkvkcvlllltdseydklggdsvfprn.qdflk
TKYGHIGVSVLSKQEKGDVISTKLeVTRKKVRRKTheVRHLHHV-SWPDKCIPEV-ACSVLDLLDDVQTSQQQCG-NAPVLVQCSNGVGRSGTFCVISSV
. | | . . | || . |. .. . |. |.|| .|| . || . .. . ..|. .. . | . |.||.|||... .
feersirvgefkrvelgdgwvlkv.lsvsngdyks..flhvhhykawphnsipsdgspkfvkqiwqlqsvlrkysdstptvymslsgcgragtfalfeta
IERLKTEQV-IDVFQVIKRIRVNRPGAVESLTQYVFCYQIIQKY
|..|| .|. .... .| | ||. |.|. . | .. ..
hlslhseqasldlvkclenvrngrlhavqnlsqfsvvytllaeh
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 649-880 | 9e-72 | 236.6 | Pfam-A | 1-234 (235) | alignment | ||
Range on Protein: 649-880
Range on HMM: 1-234/235.0
NLQKNRFCDIVALNSCRVMLrkEHADEESDYINAVFLHAHRERNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHEL-DQEYPQYWP--DHGATKY
|..|||. ||.. .. || | .. ...|||||| ... ..| ..|||||.|| .|.|||||||..... .||||..| | .....|||| ... ..|
nkkknRykdilpydktrvkl..kgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeeslty
GHIGVSVL--SKQEKGDVISTKLEVTRKKVRRKTHEVRHLHHVSWPDKCIPEVACSVLDLLDDVQTSQqQCGNAPVLVQCSNGVGRSGTFCVISSVIERL
|.| | . .|... ... .|||.. || .....||..||. .|||...|| . |.|||...|..|. . ..||.|.||.||||.|||.... ..|.|
gdikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkveksk.eaksgpvvVhCsaGvgRtgtfvaldilleql
KTEQVIDVFQVIKRIRVNRPGAVESLTQYVFCYQIIQ
..|. .||.|..|..| .|||.|.||.||.|.|..|.
eaeeevdvlqivkelRkqRpgmvqsleqYiflykail
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 649-880 | 9e-72 | 236.6 | In-house | 1-234 (235) | alignment | ||
Range on Protein: 649-880
Range on HMM: 1-234/235.0
NLQKNRFCDIVALNSCRVMLrkEHADEESDYINAVFLHAHRERNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHEL-DQEYPQYWP--DHGATKY
|..|||. ||.. .. || | .. ...|||||| ... ..| ..|||||.|| .|.|||||||..... .||||..| | .....|||| ... ..|
nkkknRykdilpydktrvkl..kgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeeslty
GHIGVSVL--SKQEKGDVISTKLEVTRKKVRRKTHEVRHLHHVSWPDKCIPEVACSVLDLLDDVQTSQqQCGNAPVLVQCSNGVGRSGTFCVISSVIERL
|.| | . .|... ... .|||.. || .....||..||. .|||...|| . |.|||...|..|. . ..||.|.||.||||.|||.... ..|.|
gdikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkveksk.eaksgpvvVhCsaGvgRtgtfvaldilleql
KTEQVIDVFQVIKRIRVNRPGAVESLTQYVFCYQIIQ
..|. .||.|..|..| .|||.|.||.||.|.|..|.
eaeeevdvlqivkelRkqRpgmvqsleqYiflykail
|
|||||||||
subfamily_Sponge-PTP6_pd | Subfamily Sponge-PTP6 | 649-880 | 3.3e-45 | 149.3 | In-house | 48-276 (439) | alignment | ||
Range on Protein: 649-880
Range on HMM: 48-276/439.0
NLQKNRFCDIVALNSCRVMLRKEHADEESDYINAVFLHAHRERNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHELDQeypqYWPDHGATKYGHI
. |||. |..|.. ||.|.. | |||| ... . . . .|||| | ||..||||.| . ||||| || | . ||| . . || |
dqtknrykdvgafdhtrvtlqeipgvphshyinanyikGyyddklyiatqgpkkettddfwrlviekktvtivmltnlvesyk....ywpsdaevcygdi
GVSVLSKQEKGDVISTKLEVTRKKV-RRKTHEVRHLHHVSWPDKCIPEVACSVLDLLDDVQTSQQQCGNAPVLVQCSNGVGRSGTFCVISSVIERLKTEQ
| | . | . . . | .. .| . | ..|...|||| .| | |||.| ....... ||.|.|| ||||.|| . .|.||.|.
avrvdrnielpnyvirgfkvfnerdttekertvlqfhyiawpdknvpaqashvldflrainsandkeeygpvvvhcsagvGrtGtiialdialeqlklen
VIDVFQVIKRIRVNRPGAVESLTQYVFCYQIIQ
.|. ..| .| .| |..| |||| |. .
kvdikgivkvlrkqrkqmvqalcqyvfiynavl
|
|||||||||
0041856 | (Phosphotyrosine protein) phosphatases II | 649-882 | 4.8e-41 | 135.7 | In-house | 1-170 (182) | alignment | ||
Range on Protein: 649-882
Range on HMM: 1-170/182.0
NLQKNRFCDIVALNSCRvmlrkehadeESDYINAVFLHAHRERNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNnlheldqeYPQYWPDHGatkyghi
|| |||. ||. . | .||||| .. . . |||||.|||.||.||.||. ...|.|||.|. ..|||..
nldknrysdilpydhsr..........dldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlt........eelywpell.......
gvsvlskqekgdvistklevtrkkvrrkTHEVRHLHHVSWPDKCIPEvACSVLDLLDDVQTsqqqcGNAPVLVQCSNGVGRSGTFCVISSVIERlkteQv
.... ......||| ..|. ..||....|. . |||| || ||||.||.... .... .
............................erlgiqylylpwpDhgvpd.ldelldfieevle.....eggpvlVHCsaGvgRtgtlvaaylmkkl....g.
IDVFQVIKRIRVNRPGAVESLTQYVFCYQIIQKY
.......| .| |||.|... ||.|..... .
vsleeavklvrsrRpgmvitpnqyfflqlallel
|
|||||||||
subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 649-876 | 1.4e-40 | 133.9 | In-house | 8-234 (239) | alignment | ||
Range on Protein: 649-876
Range on HMM: 8-234/239.0
NLQKNRFCDIVALNSCRVMLRKEHADEESDYINAVFLHAHR-ERNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHELD-QEYPQYWPDHgATKYG
| |||...||. . ||.| | | |||||| .|. . .|.|||| . . |||||. . |||| | | .. ||||| ..||
nkaknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpds.tskyc
HIGVSVLSKQEKGDVISTKLeVTRKKVRRKTHEVRHLHHVSWPDKCIPEVACSVLDLLDDVqTSQQQCGNAPVLVQCSNGVGRSGTFCVISSVIERLKTE
. |.. . | | . | . . . . | . | |||| .|. | .|| | . | . | | ...|| ||||.|.| || ... . | .
nlrvtlrktevfadyiirtf.vmsqvgqteeryvyqyhftvwpdkgvpqyatavlglrrki.tkdslpgarpwvihcsagvgrtgaflvidamlrqakkq
QVIDVFQVIKRIRVNRPGAVESLTQYVFCY
. .|.|. .| || .|| |.. |||| .
ktvdifnyvkairedrphmvqtseqyvfih
|
|||||||||
subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 649-876 | 1.4e-40 | 134.0 | In-house | 7-233 (239) | alignment | ||
Range on Protein: 649-876
Range on HMM: 7-233/239.0
NLQKNRFCDIVALNSCRVMLRKEHADEESDYINAVFLHAHR-ERNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHELD-QEYPQYWPDHgATKYG
| |||...||. . ||.| | | |||||| .|. . .|.|||| . . |||||. . |||| | | .. ||||| ..||
nkaknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpds.tskyc
HIGVSVLSKQEKGDVISTKLeVTRKKVRRKTHEVRHLHHVSWPDKCIPEVACSVLDLLDDVqTSQQQCGNAPVLVQCSNGVGRSGTFCVISSVIERLKTE
. |.. . | | . | . . . . | . | |||| .|. | .|| | . | . | | ...|| ||||.|.| || ... . | .
nlrvtlrktevfadyiirtf.vmsqvgqteeryvyqyhftvwpdkgvpqyatavlglrrki.tkdslpgarpwvihcsagvgrtgaflvidamlrqakkq
QVIDVFQVIKRIRVNRPGAVESLTQYVFCY
. .|.|. .| || .|| |.. |||| .
ktvdifnyvkairedrphmvqtseqyvfih
|
|||||||||
subfamily_Cele-PTP-15_pd | Subfamily Cele-PTP-15 | 649-883 | 5.9e-28 | 92.6 | In-house | 35-270 (285) | alignment | ||
Range on Protein: 649-883
Range on HMM: 35-270/285.0
NLQKNRFCDIVALNSCRVMLRKeHadeESDYINAVFLHA-HRERNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHELDQEY-PQYWPDHG--ATK
| . ||..|. ... ||.|.. | . ||| | ... ......|.|| || ||. |||.|. . | ..|| | | | |.|.. |
npdlnryadvrcieetrvvlkn.h...drdyihaswmrmpgkdqstyittqgplpetlsdfwhmiyqekiayvlmlctlfeggvekcalyypeklgevvk
YGHIGVSVLSKQEKG--DVISTKLEVTrkKVRRKTHEVRHLHHV---SWPDKCIPEVACSVLDLLDDVQTSQQQcgNAPVLVQCSNGVGRSGTFCVISSV
.|. ... .|. | | |. . . | .. || |||. || | ...| |. . . . |. |.|| ||||. || |
fgkyeitlteckeeaiagtilnaltvi..ntedasseplymnhvqvpwwpdqlapedarpmielykwvkkvnpk..ekpicvhcsagvgrtatfvgidya
IERLKTEQVIDVFQVIKRIRVNRPGAVESLTQYVFCYQIIQKYL
|. . |....... .| | ||.| |..| | .. .|.
tirimenpniemldivremramrfqavqshmqflflyvvlmeyf
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 650-810 | 3e-19 | 63.8 | In-house | 29-193 (319) | alignment | ||
Range on Protein: 650-810
Range on HMM: 29-193/319.0
LQKNRFCDIVALNSCRVMLRKEHADEESDYINAVFLHAHRE-RNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHELD-QEYPQYWPDH----GAT
.|.|. ..| | ||.|.. |... |..| .. ... .| .||.| .| .. ||||.| . .|| | .|.|| . ..|.| . .
kdksrvinvvPlPetrvvlqrigdddkdeyldasyvrGyddapnsyiaaqvsledsssdfwrtvweqqsrvivqltdlselGikvcaeylPtketldnts
KYGHIGVSvLSKQEKGDVISTKLEVTRKKVRRKTHEVRHLHHvSWPDKCIPEVACSVLDLLDDVQTS
||.| |. | ..| .| . . .. . .. |. | . |.. .| ... .| .|..|
lyGdilvt.lkgrevkdryaistlllkrvdkeesrelthywy.kwleaevPaeeaaliamllevrss
|
|||||||||
subfamily_Cele-PTP-11_pd | Subfamily Cele-PTP-11 | 653-889 | 2e-19 | 64.5 | In-house | 47-282 (312) | alignment | ||
Range on Protein: 653-889
Range on HMM: 47-282/312.0
NRFCDIVALNSCRVMLrkehADEESDYINAVFLHAHRERNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHELDQEY-PQYWPDHG-AT------K
||. .| . | | | .| || | |.. . |..|| || .|. ||... .|..| . | | .| |
nrypniqcwdrgrftl....agdenfyihanfvkictkperfvctqgplentcthfwqlalslgstsiillcgfvedgsekcakyisdivgfvdledhrv
YGHIGVSVL-SKQEKGDVISTKLEVTRKKvRRKTHEVRHLHHVSWPDKCIPEVACSVLDLLDDVQTSQQqcgnaPVLVQCSNGVGRSGTFCVISSVIERL
| . . | . | | | . . | ||||. .|. . | || |. .. ||. .|| ||||.||...| |.| |
yteycteieiggkskdkithrvlkvvvka.tgqesklnhyqwaswpdhgmpdscdtalrllsavkkdkk.....pviahcsagvgrtgtlaliesmiaal
KTEQVIDVFQVIKRIRVNRPGAVESLTQYVFCYQIIQKYLGSFSDY
. . .| .. .| .| .|. . |||.. ... ..| | . |
rhprkqnvkdsfvllrkdrarsvrvfpqyvyalrcvleflyskgly
|
|||||||||
subfamily_Cele-PTP-1_pd | Subfamily Cele-PTP-1 | 661-879 | 6.3e-19 | 63.2 | In-house | 30-255 (290) | alignment | ||
Range on Protein: 661-879
Range on HMM: 30-255/290.0
LNSCRVMLRKEHADEESDYINAVFLHAHrERNAFIATQHPLLET-------VEDFWRMVTDYDIGTIVMLNNLHELDQEYP-----QYWPDHGA--TKYG
.. ||.|. .||| | .. . ..|.|| |. .. .|.|| |. . . .||| . .| ... .| |.. |..
veatrvvLkgygkrfnddyiHAnrvtcp.nglrliltqsPqekitekrnStiekfwwmakqEkvkqvVmlcefeeksantslfaCakYvpesvgeelkfk
HIGVSVLSKQEKGDVISTKLEVTRKKvrRKTHEVRHLHHVSWPDKCIPEVACSVLDLLDDVQTSqqqcgNAPVLVQCSNGVGRSGTFCVISSVIERLK-T
. |. || .. ||. .|.|. . .. . | | ..| . ..| ..|.|.. |..| ..||.| | .|. || .. | . |
gltvkCkskekeddvetRelvvkfdd..eeeftvtHsllkgWnklnvqedtktllsliqkvkas.....ktpvivHcvdGiSrsAalaaiilgyQkiaet
EQVIDVFQVIKRIRVNRPGAVESLTQYVFCYQII
.. . . .|.| .| .| |. | ... | |
sgsvkledvlkalrkqralaitsalelafvdagi
|
|||||||||
0044763 | (Phosphotyrosine protein) phosphatases II | 663-883 | 3.3e-28 | 93.9 | In-house | 4-171 (178) | alignment | ||
Range on Protein: 663-883
Range on HMM: 4-171/178.0
SCRVMLRKEHADEESDYINAVFLHAHrernaFIATQHPLletvEDFWRMVTDYDIGTIVMLNNLHELD-QEYPQYWPDHGAtkyghigvsvlskqekgdv
.|| | . | ||||||.. . ......| .|..... ...|..||.|.. || .....|||.
rtrvllsnleglersdyinaseilpg.....lylgslpp....addlellkelgithivnlteelelgflkcdpywpeeag...................
istklevtrkkvrrkthevRHLHHVSWPDKCIPEVACSVLDLLDDVQTSQQQCGnAPVLVQCSNGVGRSGTFCVISSVIERlkteQViDVFQVIKRIRVN
. .|. .|| . |.. .|.... ... ....| |||| || |||||||.... .... .. .....|...|
...................iqylhipipDhgvpdllehflefvefieealdekg.gpvlVHCsaGvgRsgtlvaaylmkkl....gl.sleeaielvrer
RPgAVESLTQYVFCYQIIQKYL
|| .|.. |. ..|.. ...|
Rp.ivpnpgqlrqLyefelrll
|
|||||||||
0046846 | (Phosphotyrosine protein) phosphatases II | 669-884 | 2.4e-38 | 127.0 | In-house | 4-174 (176) | alignment | ||
Range on Protein: 669-884
Range on HMM: 4-174/176.0
RKEHADEESDYINAVFLHAHRernaFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHELDQEY-PQYWPDhgATKYGHigvsvlskqekgdvistkle
|. . |. .||||| .. .| .||||.|| .|..||..|. ...|...|.|....||.. |.|||. .|.|.
rllgldldldyinanlilgsr....piatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpe..leklgi....................
vtrkkvrrkthevrHLHHVSWPDKCIPEVaCSVLDLLDDVQTSQQQcgNAPVLVQCSNGVGRSGTFCVISsvieRLKTEQVIDVFQVIKRIRVNRP-GAV
. .|. ||| ..|. .|.||. ... ... . |||| || |.||.||.... |..|. ..|.......| || |||
..............qylhlpwpDhgvpdl.elllellefirealke..ggpvlVHCsaGigRtgtlvaay....llelekglsveealalvreqRplgav
ESLTQYVFCYQIIQKYLG
.. || |.|. ....|.
qtpeQyrflyefellllk
|
|||||||||
0043147 | (Phosphotyrosine protein) phosphatases II | 674-877 | 1.9e-38 | 127.2 | In-house | 2-155 (172) | alignment | ||
Range on Protein: 674-877
Range on HMM: 2-155/172.0
DEESDYINAVFLHAHRERNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLheldqeypqywpdhgatkyghigvsvlskqekgdvistklevtRKKV
|| |||||| .|. .. . ||||| || .|..|||||. ...|..||.|..| .
degsdyinasyldlyyipdrfiatqgplrntladfwrmlkelgithivnltel...........................................lydp
RRKTHEVRHLHHVSWPDKCIPeVACSVLDLLDDVQTSQQQCGNAPVLVQCSNGVGRSGTFCVISSVIerlkteQVIDVFQVIKRIRVNRPGAVESLTQYV
.... ......||| . | . .|..|. ... .... . |||| || ||||.||.... .. . ........ .| |||||.. ||
ellerlgiqylylpwpDhgvp.llellleflefidellalspggpvlVHCsaGvgRtgtlvaaylml......lglsleeavalvrekRpgavqnpsqyr
FCYQ
|.|.
flyy
|
|||||||||
subfamily_Sponge-PTP-4_pd | Subfamily Sponge-PTP-4 | 676-789 | 2e-10 | 35.1 | In-house | 12-122 (130) | alignment | ||
Range on Protein: 676-789
Range on HMM: 12-122/130.0
ESDYINAVFLHAHRERNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHELDqeypQYWPDHGATK-Y-GHIGVSVLSKQEKGDVISTKLEVTRKkV
. .|||| |. . .. ||||| .| |||.|. . . .|.| . | | .|||| . | .| |.. ..| . ...||. .. .
gntyinasfvGllgrtaeylltqhpladtsmdfwkmmleryvnvlvvlgsveeed....eywpdsePlewyeediivtltdrdefknikasnleiesd.l
RRKTHEVRHLHHVSWP
. . . .. ||
neshqaltmfqisnwp
|
|||||||||
0051429 | (Phosphotyrosine protein) phosphatases II | 677-886 | 3e-45 | 150.3 | In-house | 4-228 (272) | alignment | ||
Range on Protein: 677-886
Range on HMM: 4-228/272.0
SDYINAVFLHAHRE---RNAFIATQHPLLETVEDFWRMvTDYDIGTIVMLNNLHELDQEY-PQYWP------------DHGATKYGHIGVSVLSKQEKGD
|.|||| .. .........|| |..||||. ...| |||.| ...|.... ..||| .. ||.. | .||.. . |
sgyiNardvggygrvvkpgrlyrsggplpltaadfwrl.kelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseellld
VISTKLEVTRKKVRRKTHEVRHLHHVSWPDKCIP-EVACSVLDLLDDvqtsqqqcgNAPVLVQCSNGVGRSGTFCVISSVIERLKTEQVID--------V
.| ..|..|.. ...||.|||. .||| ..| | ...|.|| | . |||| || |..|.||.... ..... |...| .
yilrellltlllsagearevmhlhytdwpdhgvpqeallellellld.........ggpvlvHCsaGkdRTGtvvallllllgvsletivddYlltnlyl
FQVIKRIRVNRPGAVESLTQYVFCYQIIQKYLGSF
.......| |||||.. .||.|.|......| |.
eeaveelraqrpgavqteeqylflyeallellrsl
|
|||||||||
0036282 | (Phosphotyrosine protein) phosphatases II | 677-877 | 4.3e-41 | 135.8 | In-house | 2-164 (174) | alignment | ||
Range on Protein: 677-877
Range on HMM: 2-164/174.0
SDYINAVFLHAHRERNAFIATQHPLLetvedFWRMVTDYDIGTIVMLNNLHELD-QEYPQYWPDhgatkyghigvsvlskqekgdvistklevtrkKVRR
|||||| .|. .. . .||.|.|| ||.|. ...| |.|||....||. ..|||. .
sdyinaspldlsyitprliagqgpla.....fwemlkelgittvvmlleekelglykcinywpe................................lred
KTHEVRHLHHVSWPDKCIPEVACsVLDLLDDVQTSQQQCGNAPVLVQCSNGVGRSGTFCVISSVIERLKtEQVIDVFQVIKRIRVNRPGAVESLTQYVFC
.... ..... ||| . |... .|.... |.. ...... |||| || ||||.||.... .. .|. | ..|........| |||.|.. || |.
lerlgiqylylpwpDhgvpdlsi.llefvkfveealsedpggpvlVHCsaGvgRtGtlvaaylmlrgll.eslvdaldlvrelRlqrpgmvqtpsQyrfl
YQ
|.
yy
|
|||||||||
0051082 | (Phosphotyrosine protein) phosphatases II | 677-879 | 4.7e-30 | 99.5 | In-house | 3-149 (151) | alignment | ||
Range on Protein: 677-879
Range on HMM: 3-149/151.0
SDYINAVFLHAHrernaFIATQHPlletVEDFWRMVTDYDIGTIVMLNNLHELDqEYPQYWPDHGatkyghigvsvlskqekgdvistklevtrkkvrrk
|||||. .. . ......| .||.... ...| |||.|....| . .|.|.|..|
sdyinfsyvtgg.....lyrsggp....ladflellkelgiktivnlrseeerg.ycpeylpelg...................................
tHEVRHLHHVSWPDKCIPEVACSVLDLLDDVQTsqqqCGNAPVLVQCSNGVGRSGTFCVISSVIERlkteqvIDVFQVIKRIRVNRPGAVESLTQYVFCY
.||.|.. ..||| .|. .||..|. .. ..| |||| || |.||.||.... .... ........ .| |||.| . .|..|..
.ievlhipildwpdpglplsfdavleflellld....kkngpvlvHCsaGkgRTGtlvalylmllg......vsleealeeyrlkrpgvvqpnqqflfql
QII
. .
fal
|
|||||||||
subfamily_Cele-PTP-19_pd | Subfamily Cele-PTP-19 | 680-872 | 4.1e-27 | 89.7 | In-house | 78-270 (301) | alignment | ||
Range on Protein: 680-872
Range on HMM: 78-270/301.0
INAVFLHAHRERNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHE-LDQEYPQYWPDHGATK--YGHIGVSVLSKQE--KGDVISTKLEVTRKKVR
| | .. .. . . ||||| || .| |||| |.. ||. .|||| . | | . .| | . . | | . . .|. . ... .|||. .
ihanwiptsGhphrfiatqgPlkntsedfwamlvqydvekivmlgqkvekleekceeylpvkisekldigrfkikiknkelilnkkiskrtlevedstgk
RKTHEVRHLHHVSWPDKCIPEVACSVLDLLDDVQTSQQqcgnaPVLVQCSNGVGRSGTFCVISSVIERLKTEQVIDVFQVIKRIRVNRPGAVESLTQY
.|. | | ...|.|. .|. . ||.. |. |.. |..|.||.|.||| .| . ...... |.. . .|..| .| .| .|
fatrtvthyqysewtdrgvPkshaelfdlmelvkksek.....PivvhcsaGiGrsvafigteylareveadptieltealkhlrehrwngvqtnsql
|
|||||||||
0049260 | (Phosphotyrosine protein) phosphatases II | 688-877 | 7.8e-34 | 111.9 | In-house | 5-144 (152) | alignment | ||
Range on Protein: 688-877
Range on HMM: 5-144/152.0
HRERNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHELDQE-YPQYWpdhgatkyghigvsvlskqekgdvistklevtrkkvrrkthevrHLHHV
.. ..|||||.|. .|..|||||. ...|.|||||..|.||. . .||. . .|.
yampfefiatqgpgpntladfwrmlkelgittivmltellelgklkceqyi............................................qylhl
SWPDKCIPEVACSVLDLLDDVQTSqQQCGNAPVLVQCSNGVGRSGTFCVISSVIerlkteQVIDVFQVIKRIRVNRPGAVESLTQYVFCYQ
||| . |. . .|.||. .. .. . |||| || ||||.||.... .. . ..........| |||||.. |. |.|.
pwpDhgvpdlsqlllflllfiekl.aldkggpvlVHCsaGvgRtgtlvaaylml......lgvsleeavalvrekRpgavpnpgqlrflye
|
|||||||||
subfamily_Anemone-PTP-3_pd | Subfamily Anemone-PTP-3 | 688-878 | 4.8e-33 | 109.0 | In-house | 1-199 (199) | alignment | ||
Range on Protein: 688-878
Range on HMM: 1-199/199.0
HRERNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHELDQ-EYPQYWP--DHGATKYGHIGVSVLSKQEKGDVISTKLEVTRKK-VRRKTHEVRHL
|. . .||||||| ||. |||.|| . | |||.|. . .|| ||| . |..||| . |.. . | | | | .| . | |. |
hkgqrryiatqhplretmadfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishy
HHVSWPDKCIPEVACSVLDLLD--DVQTSQQQCGNAPVLVQCSNGVGRSGTFCVISSVI---ERLKTeQVIDVFQVIKRIRVNRPGAVESLTQYVFCYQI
|| .| |.|| | .. .| .| .|||.|.||.| | .| | . . | || |.|.|.| ||.| | | . || .| | ||.
qftswkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheeskt.svvdlfevakrlrqarcgiisslqhynfiyqv
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 689-880 | 2.8e-33 | 109.9 | In-house | 233-435 (440) | alignment | ||
Range on Protein: 689-880
Range on HMM: 233-435/440.0
RERNAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHelDQEYPQYWPDHG-ATKYGHIGVSvlsKQEKGDVISTKLEVTRKKVRRKTHEVRHLHHVS
.||||||| || || ||||.| || | ||.|||.| |. ||| . .| . | .. .. |. | . . ||.| . .
skknafiatqmpldstvldfwrlvhdyristiimlnqln..dktcsiywpvntrsvtfgpftvg...hkgsenmnrvkvrtlelkykeevheirqfevqt
WPDKCIP-----EVAC--SVLDLLD-----DVQTSQQQ--CGN-APVLVQCSNGVGRSGTFCVISSVIERLKTEQVIDVFQVIKRIRVNRPGAVESLTQY
|| . | .||.|.| ..| | .| |. |.||.| |. || || . ..|.|. . ||||| .. .|. || | .||.|
wptwiqsdgvqsqeqcmdavlqlmdylrkceiqrsteqsrpgdgppilvhclsgieesgvfctvmncleqlnndgaidvfqnlrllrlsrpnfvptltdy
VFCYQIIQ
..||...
llcykllt
|
|||||||||
subfamily_Cele-PTP-5_pd | Subfamily Cele-PTP-5 | 691-883 | 9e-14 | 44.8 | In-house | 114-309 (346) | alignment | ||
Range on Protein: 691-883
Range on HMM: 114-309/346.0
RNAFIATQHPLLE---TVEDFWRMVTDYDIGTIVMLNNLHELDQEYPQYWPDHGaTKYGHIGVS---VLSKQEKGDVISTKLEVTRKKVrRKTHEVRHLH
. .| .| | .| ||||| |. . .| . .. | . . | | . | . || .|| . . .. |
ehklivaqlpqmenesfvedfwymiyqeqihlvylmvpddklkntttslfnden.ggyqytgkmfinnrradvsgdpkeytievlpegn.sdsvicqvhh
HVSWPDKCIPEVACSVLDLLDDVQtSQQQCGNAPVLVQCSNGVGRSGTFCVISSVIERLKTEQVIDVFQVIKRIRVNRPGAVESLTQYVFCYQIIQKYL
| | | . .. .. . |..| || | | | ||. .| |..| ......| |. .|||.|||..|| | |. |.
hapwkhlqqppktlpiikmihqfl.sekqvqnagvcvvslfgcgracsfigalyainqlnngiepniceimknikqqrpggvesfaqyasiyaivfdyi
|
|||||||||
subfamily_Nvec-PTP-3_pd | Subfamily Nvec-PTP-3 | 692-878 | 9.7e-33 | 108.0 | In-house | 4-198 (198) | alignment | ||
Range on Protein: 692-878
Range on HMM: 4-198/198.0
NAFIATQHPLLETVEDFWRMVTDYDIGTIVMLNNLHELDQ-EYPQYWP--DHGATKYGHIGVSVLSKQEKGDVISTKLEVTRKK-VRRKTHEVRHLHHVS
.||||||| ||. |||.|| . | |||.|. . .|| ||| . |..||| . |.. . | | | | .| . | |. | |
rryiatqhplretladfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyqfts
WPDKCIPEVACSVLDLLD--DVQTSQQQCGNAPVLVQCSNGVGRSGTFCVISSVI---ERLKTeQVIDVFQVIKRIRVNRPGAVESLTQYVFCYQI
| .| |.|| | .. .| .| .|||.|.||.| | .| | . . | || |.|.|.| ||.| | | . || .| | ||.
wkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheeskt.svvdlfevakrlrqarcgiisslqhynfiyqv
|
|||||||||
subfamily_Cele-PTP-9_pd | Subfamily Cele-PTP-9 | 696-880 | 6.6e-21 | 69.5 | In-house | 39-218 (255) | alignment | ||
Range on Protein: 696-880
Range on HMM: 39-218/255.0
AtqhplleTVEDFWRMVTDYDIGTIVMLNNLHELD-QEYPQYWPDHGATKYGHIGVSVLSKQEKGDVISTKLEVTRKKV-RRKTHEVRHLHHVSWPDKCI
||. |.... . ..||| ...| . .. .|.| | |.| . . ||. ||.| . ..|||.|.| .. |..|
l.......tvdkfyqtivqtktevvvmlcdfaeegvekcssyfplekdeklkladvnvtttkssadvvlrtleitstlgekkkthtvkhysykGWiekna
PEVACSVLDLLDDVQTSQqqcgnaPVLVQCSNGVGRSGTFCVISSVIE----RLKTEQV--IDVFQVIKRIRVNRPGAVESLTQYVFCYQIIQ
|| | .| .| |. |. .|.|.||.|.||| .| .. .| |.| . .| .... .| .|..|.. | |. ..
Pelareilnilkvvrdsk......svvvhCstGiGrsaafvlaelvyqkmirsldttetveldylslleelrskrkraihtPlqlafsilmvl
|
|||||||||
subfamily_hpo-7_pd | Subfamily hpo-7 | 696-879 | 7.9e-19 | 62.6 | In-house | 42-223 (263) | alignment | ||
Range on Protein: 696-879
Range on HMM: 42-223/263.0
AtqhpLLETVEDFWRMVTDYDIGTIVMLNNLHELD-QEYPQYWPDHGATKYGHIGVSVLSKQEKGDVISTKLEVTRK--KvRRKTHEVRHLHHVSWPDKC
|..|.. |.... ..||| . .| . .. .|.| | |.| . . . ||. ||.. . ..|||.|.| .. |..|
l....lvqtidkfyqtivqtktevvvmLcDfneegvekcssyfPlekdekqklanvnvcttkvqsdvllktlellstlge.KkkthtvkhysykgWiekn
IPEVACSVLDLLDDVQTSQqqcgnaPVLVQCSNGVGRSGTFCVISSVIE----RLKTEQV--IDVFQVIKRIRVNRPGAVESLTQYVFCYQII
|| | ..| .|. .. |. .. | ||.|.||| | |. .| |.| . .| .... .| .|..|.. | | ..
dpelareilnilkvarnsk......slvvhcstGiGrsaafsvaElvyqkmirsldttstveldylsLleelrssrkraihtPmqLafsilmv
|
|||||||||
subfamily_Cele-PTP-7_pd | Subfamily Cele-PTP-7 | 699-882 | 2.4e-20 | 67.2 | In-house | 98-287 (302) | alignment | ||
Range on Protein: 699-882
Range on HMM: 98-287/302.0
HPLLETVEDFWRMVTDYDIGTIVMLNNLHELD-QEYPQYWPDH--GATKYGHIGVSVLSKQE-------KGDVISTKLEVTRKKVRRKT-HEVRHLHHVS
| .|.| .| .. .|... .| | .. | . . . .|. |. | |.|. | .| .. | .. ..|.. .|...|. . | |.. .
vpkkstlekhwalieqynvaivvqlcsfvedeekkcaeyysdkvggelkfgrytvktvsvktdleeftdkksfklytveiknekkkkkvkktvdilafsa
WPDKCIPEVACSVLDLLDDVQTSQQQcgnapVLVQCSNGVGRSGTFCVISSVIERLKTEQVIDVFQVIKRIRVNRPGAVESLTQYVFCYQIIQKY
|||. |. | . ||.| .. ... ||| ||.||||.||. | |. ....| |. .... .| | ||| . .| .. .. |
wpdhGapkeaytaldilkfcesykkn.....vlvhcsaGvGrtGtlvaikyGiqlcskkkvtdllsivlpvrqcryGavqdeqqliylllcvtkg
|
|||||||||
subfamily_PTPRD_pd | Subfamily PTPRD | 732-890 | 2.8e-57 | 189.7 | In-house | 132-288 (564) | alignment | ||
Range on Protein: 732-890
Range on HMM: 132-288/564.0
EYPQYWPDHGATKYGHIGVSVLSKQEKGDVISTKLEVtRKKVRRKTHEVRHLHHVSWPDKCIPEVACSVLDLLDDVQTSQqQCGNAPVLVQCSNGVGRSG
.. .|||..| ..||.. |.. ...|. |.. ..... .|| .....|||. |..||||...|| |.|.|||...|.... .... |..|.||.||||.|
kchkYWPekgtetygeltVtleeeeeladyeirtfkl.kkkkssesreVrqFhFtsWPdhgvpesatslLdlirkvraln.epdagPivVhCSaGVGRTG
TFCVISSVIERLKTEQVIDVFQVIKRIRVNRPGAVESLTQYVFCYQIIQKYLGSFSDYA
||.||....||.|.|...|..|..|..| .|. |.. .||.|....|...| ....
tfividamlerikeektvDiyqyvkalrkqRnamVqteeQYiFiheailealacgntev
|
|||||||||
subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 757-882 | 9.1e-10 | 32.8 | In-house | 200-343 (350) | alignment | ||
Range on Protein: 757-882
Range on HMM: 200-343/350.0
EKGDVISTKLEVTRkkvrrkTHEVRHLHHVSWPDK---CIPEVACSVLD----LLDDVQTS--QQQCGNAPVLVQCSNGVGRSGTFCVISSVIE---RLK
....... .| .. ..| .|. |.| || ..|. |.|| . .. .|.|| || |||| ||.. . |... |.
dnnsltaitlaasd......PyvvyqlqvknWkDlslllnPesilqalevkndliddlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsdfeile
---T--------EQVID-VFQVIKRIRVNRPGAVESLTQYVFCYQIIQKY
.. | ........| | | .|.|..|.|. .. |
nltkesrkldvaaktrDlisiivnelrkqrismvqnldqfifiYeallfy
|
|||||||||
0048179 | (Phosphotyrosine protein) phosphatases II | 764-877 | 5.9e-20 | 66.9 | In-house | 48-139 (144) | alignment | ||
Range on Protein: 764-877
Range on HMM: 48-139/144.0
TklevtrkkvrrktheVRHLHHVSWPDKCIPEVACSVLDLLDDVQTSQQqcGNAPVLVQCSNGVGRSGTFCVISsvieRLKTEQvIDVFQVIKRIRVNRP
. . ...|..||| ..|. . .|..|. ... .. . |||| || ||||.||.... ..|... ..........| ||
e...............giqylhlpwpDhgvpdllellleflefieeale..eggpvlVHCsaGvgRtgtlvaay....lmkklg.lsleealalvrsrrp
GAVESLTQYVFCYQ
|||.. |. |...
gavpnpgqlrfLle
|
|||||||||
0048076 | (Phosphotyrosine protein) phosphatases II | 770-882 | 4.3e-20 | 67.3 | In-house | 37-142 (145) | alignment | ||
Range on Protein: 770-882
Range on HMM: 37-142/145.0
RKKVRRKTHEVRHLHHVSWPDKCIPEVACSVLDLLDDVQTSQQQcgNAPVLVQCSNGVGRSGTFCVISSVIErlktEQvIDVFQVIKRIRVNRPGAVESL
. .... ......||| ..|. . .|..|. ... ... . |||| || ||||.||.... ... .. ..........| |||||..
tselellerlgiqylylpwpDhgvpdllellleflefieealke..ggpvlVHCsaGvgRtgtlvaaylmll....lg.vsleealelvrsqrpgavpnp
TQYVFCYQIIQKY
|. |.|. ....
gqlrflyefelel
|
|||||||||
0038934 | (Phosphotyrosine protein) phosphatases II | 779-878 | 5.6e-06 | 21.6 | In-house | 78-172 (194) | alignment | ||
Range on Protein: 779-878
Range on HMM: 78-172/194.0
EVRHLHHVSWPDKCIPEVACSVLDLLDDVQTSQQQCGNAPVLVQCSNGVGRSGTFCVIsSVIERLKTeqviDVFQVIKRIRVNRPGAVESLTQYVFCYQI
. .. .||.. . .|. || |.. ... . |.| | |.||.||... |.||. .. . |...| ||||... .. ..
agieylklpfpddgtvPsleillrfldlvdeflnedpggvvaVHCkaGlgRtGtlvaa.YLiyrlgm....saeeAialfrekRpgaipnqdyleallkr
|
|||||||||
PTPc_DSPc_SM00012 | 780-880 | 8.3e-32 | 104.9 | In-house | 2-104 (105) | alignment | |||
Range on Protein: 780-880
Range on HMM: 2-104/105.0
VRHLHHVSWPDKCIPEVACSVLDLLDDVQTSQQQCG-NAPVLVQCSNGVGRSGTFCVISSVIERLKTE-QVIDVFQVIKRIRVNRPGAVESLTQYVFCYQ
|.|.|. .|||...|| . |.|.||..|........ ..||.|.||.||||.|||.... ....|..| . .|.||..|..| |||.|....||.|.|.
vkhyhytgwpdhgvPeesdsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgmvqteeqylflyr
IIQ
...
all
|
|||||||||
subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 802-882 | 1.1e-06 | 22.3 | In-house | 249-343 (349) | alignment | ||
Range on Protein: 802-882
Range on HMM: 249-343/349.0
DLLDDVQTS--QQQCGNAPVLVQCSNGVGRSGTFCVISSVIERLK--TEQ--VID--------VFQVIKRIRVNRPGAVESLTQYVFCYQIIQKY
||.|| . .. ...|| || | ||.|... . .... |. ... |. .. .. .| | |. |.|....|. . ||
dliddlfarlyldtdqlstllvhcsaGcGrtGvlvtldlllsileplqnesnkiklqallkDlisiivnelrkqrismvqnlaqfiaiyealLky
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 810-882 | 3e-12 | 40.8 | In-house | 241-314 (319) | alignment | ||
Range on Protein: 810-882
Range on HMM: 241-314/319.0
SQQQCGNAPVLVQCSNGVGRSGTFCVISSVIERLKTE-QVIDVFQVIKRIRVNRPGAVESLTQYVFCYQIIQKY
| .. . |. | ||.||||.|. |..|.. . .|. |.. .| .| || . || | |.....|
sgtresqGPlvvhcsdGvGrtGlviasdiairsleeskrsvdiPqlvssvrrdrasavltkeqyefiykvlsey
|
|||||||||
subfamily_eak_pd | Subfamily eak | 815-883 | 8.4e-06 | 19.4 | In-house | 236-305 (332) | alignment | ||
Range on Protein: 815-883
Range on HMM: 236-305/332.0
GNAPVlVQCSNGVGRSGTFCVISSVIERL--KTEQVIDVFQVIKRIRVNRPGAVESLTQYVFCYQIIQKYL
.||. .|...| |.|.| || .|. . | . . | ..| ... | .| |. | |.|. .||
sfapi.iqsarGsaraGvfvvidllirlidnkkknlysvedlilkvkskrihsvlvalqhsfiyeivldyl
|
|||||||||
subfamily_Sponge-PTP-7_pd | Subfamily Sponge-PTP-7 | 820-877 | 1.4e-10 | 35.4 | In-house | 2-59 (69) | alignment | ||
Range on Protein: 820-877
Range on HMM: 2-59/69.0
LVQCSNGVGRSGTFCVISSVIERLKTEQVIDVFQVIKRIRVNRPGAVESLTQYVFCYQ
.|.|| | ||.||| | . |.|.|...|.| .. .| || | .|.| .
vvhcssgtgrtgtfiaimvemarikseklvdifnnvqymrkcrpmmvmneieyifihd
|
|||||||||
subfamily_Sponge-PTP7_pd | Subfamily Sponge-PTP7 | 821-878 | 5.4e-10 | 33.5 | In-house | 2-59 (69) | alignment | ||
Range on Protein: 821-878
Range on HMM: 2-59/69.0
VQCSNGVGRSGTFCVISSVIERLKTEQVIDVFQVIKRIRVNRPGAVESLTQYVFCYQI
|.|| | ||.||| | . |.|.|...|.| .. .| || | .|.| ..
vhcssGtGrtGtfiaimvemarikseklvdifnnvqymrkcrpmmvmneneymfihda
|