Gene NvecPTP-sf3-1 in Nematostella vectensis

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family PTP
Subfamily NvecPTP-sf3
Protein sequence
ID Type Fasta BLAST phosphatome Note
NvecP056_AA protein Get Run
NvecP056_AA_0-137 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
0043147 (Phosphotyrosine protein) phosphatases II 1-137 3.6e-24 80.8 In-house 33-155 (172) alignment
Range on Protein: 1-137
Range on HMM: 33-155/172.0
MADFWQMVWETGSGHIVMVNDDqknKETAPPSTREISHYQFTSWKEKTTPNVALFVGFVvasREVSKKYEQEKDAPVIVHCSDGQGFTGVFVALDIGVrs
.||||.|..| | .|||....      .... .|.. .|....|   ..|. .|.  |.   . . ... .... ||.|||| | | ||..||...    
ladfwrmlkelgithivnltel...lydpellerlgiqylylpwpDhgvpllelllefl...efidellalspggpvlVHCsaGvgRtgtlvaaylml..

heesktS-VvDLFEVAKRLRQARCGIISSLQHYNFIYQ
        . .|.|. . .|..|.|.. . ..|.|.|.
......lgl.sleeavalvrekRpgavqnpsqyrflyy

0049260 (Phosphotyrosine protein) phosphatases II 1-137 4e-22 74.0 In-house 22-144 (152) alignment
Range on Protein: 1-137
Range on HMM: 22-144/152.0
MADFWQMVWETGSGHIVMVNDDQKNKETAPPSTReisHYQFTSWKEKTTPNVALFVGFVVASREVSkkyEQEKDAPVIVHCSDGQGFTGVFVALDIGVrs
.||||.|..| | ..|||..... ...   .      .|... |   ..|. . .. |..   |      ..|. ||.|||| | | ||..||...    
ladfwrmlkelgittivmltellelgklkceqyi...qylhlpwpDhgvpdlsqlllflllfiekl...aldkggpvlVHCsaGvgRtgtlvaaylml..

heesktSVVDLFEVAKRLRQARCGIISSLQHYNFIYQ
        |.|.|. ...|..| |.. . ... |.|.
......lgvsleeavalvrekRpgavpnpgqlrflye

subfamily_Urchin-PTP-4_pd Subfamily Urchin-PTP-4 1-136 2.2e-21 70.7 In-house 101-229 (392) alignment
Range on Protein: 1-136
Range on HMM: 101-229/392.0
MADFWQMVWETGSGHIVMVNDDQKNKETapPSTREISHYQFTSWKEKTTPNVALfvGFVVASREVSKKYEQEKdAPVIVHCSDGQGFTGVFVALDIGVrS
. |||.||..     |.||.. ..       ..| .. ..|| | .|  |. .    ..   .||. .. |    |.|.||| | | ||| ...|  | .
lddfwrmvfqenvttiamvtklkegdkg..ddartvaqfhftewPdkdvpkhts..sllkfikevkadfGqyt.hpliihcsagvgrtgvvisidsvv.a

HEeSKTSVVDLFEVAKRLRQARCGIISSLQHYNFIY
|   || .||.|..   .|. |  .. . ..| |||
ha.kktrmvdvfnfvtnirrkrpymvqtkeqyafiy

0051082 (Phosphotyrosine protein) phosphatases II 1-137 7.5e-21 69.7 In-house 22-147 (151) alignment
Range on Protein: 1-137
Range on HMM: 22-147/151.0
MADFWQMVWETGSGHIVMVNDDQ---KNKETAPPSTREISHYQFTSWKEKTTPNV----ALFVGFVVAsrevskkyeqEKDAPVIVHCSDGQGFTGVFVA
.|||.....| |  .||......   ...|  |   .|. |.....|.. ..|      . |. .. .           |. ||.|||| | | ||..||
ladflellkelgiktivnlrseeergycpeylpelgievlhipildwpdpglplsfdavleflellld..........kkngpvlvHCsaGkgRTGtlva

LDIGVRSheesktsvVDLFEVAKRLRQARCGIISSLQHYNFIYQ
|..  .         |.|.|. . .|. |.|.. . |.. |...
lylmllg........vsleealeeyrlkrpgvvqpnqqflfqlf

0046846 (Phosphotyrosine protein) phosphatases II 1-137 7.9e-21 70.0 In-house 36-167 (176) alignment
Range on Protein: 1-137
Range on HMM: 36-167/176.0
MADFWQMVWETGSGHIVMVNDDQKNKET-----APPSTREISHYQFTSWKEKTTPNVALFVGFVVASREVSKKYeqekdAPVIVHCSDGQGFTGVFVALD
.|||..|..| | ...|......  .        |  ...  .|... | . ..|. .|.  .. . ||. |.       ||.|||| | | ||..||..
ladflemlkelgitavvnlteevelgrlkcpnywpeleklgiqylhlpwpDhgvpdlelllellefirealkeg.....gpvlVHCsaGigRtgtlvaay

IGVRsheeskTSVVDLFEVAKRLRQARC-GIISSLQHYNFIYQ
.  .         ....|. ...|. |. |.. . ..| |.|.
llel......ekglsveealalvreqRplgavqtpeQyrflye

subfamily_Anemone-PTP-3_pd Subfamily Anemone-PTP-3 1-28 9.2e-17 55.9 In-house 18-45 (199) alignment
Range on Protein: 1-28
Range on HMM: 18-45/199.0
MADFWQMVWETGSGHIVMVNDDQKNKET
|||||||||||||||||||||||||||.
madfwqmvwetgsghivmvnddqknkea

subfamily_Nvec-PTP-3_pd Subfamily Nvec-PTP-3 1-28 1.2e-16 55.4 In-house 17-44 (198) alignment
Range on Protein: 1-28
Range on HMM: 17-44/198.0
MADFWQMVWETGSGHIVMVNDDQKNKET
.||||||||||||||||||||||||||.
ladfwqmvwetgsghivmvnddqknkea

DSPc_SM00195 1-27 2.1e-06 22.7 In-house 82-108 (263) alignment
Range on Protein: 1-27
Range on HMM: 82-108/263.0
MADFWQMVWETGSGHIVMVNDDQKNKE
..|||.||||...  |||......|..
vedFWrmvweekvkiivmlteeeengk

PTPc_SM00194 1-27 2.1e-06 22.7 In-house 82-108 (263) alignment
Range on Protein: 1-27
Range on HMM: 82-108/263.0
MADFWQMVWETGSGHIVMVNDDQKNKE
..|||.||||...  |||......|..
vedFWrmvweekvkiivmlteeeengk

subfamily_Urchin-PTP-5_pd Subfamily Urchin-PTP-5 1-27 2.2e-06 22.0 In-house 105-131 (297) alignment
Range on Protein: 1-27
Range on HMM: 105-131/297.0
MADFWQMVWETGSGHIVMVNDDQKNKE
.||||.||..     |||.|||.....
vadfWamvldeqvstivmlnddnerdk

subfamily_PTPRD_pd Subfamily PTPRD 1-26 2.8e-06 21.2 In-house 104-129 (564) alignment
Range on Protein: 1-26
Range on HMM: 104-129/564.0
MADFWQMVWETGSGHIVMVNDDQKNK
..|||.||||  |  |||..  . ..
iedFWRmvweqnsstiVmltkleEkg

Y_phosphatase Protein-tyrosine phosphatase 1-26 3.8e-06 21.9 Pfam-A 55-80 (235) alignment
Range on Protein: 1-26
Range on HMM: 55-80/235.0
MADFWQMVWETGSGHIVMVNDDQKNK
..|||.|||.  .  |||........
iedFWrmvwqekvkvivmltsleekg

Y_phosphatase Protein-tyrosine phosphatase 1-26 3.8e-06 21.9 In-house 55-80 (235) alignment
Range on Protein: 1-26
Range on HMM: 55-80/235.0
MADFWQMVWETGSGHIVMVNDDQKNK
..|||.|||.  .  |||........
iedFWrmvwqekvkvivmltsleekg

0046845 (Phosphotyrosine protein) phosphatases II 2-137 1.6e-34 115.0 In-house 91-268 (284) alignment
Range on Protein: 2-137
Range on HMM: 91-268/284.0
ADFWQMVWETGSGHIVMVNDDQKNKETA------------------------------------------PPSTREISHYQFTSWKEKTTP-NVALFVGF
.|||.|||| .. .|||...   |. .                                           .  .|.. |...||| .  .| ... .. |
edFwrmvweqnvrvIVmltelvengrekcaqYwplegevltygdftvtllseevkddytvrtleltnlgytgesrtvthfhytswpdhgvppspedllef

VVASREVSKKyeQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEESK-TSVVDLFEVAKRLRQARCGIISSLQHYNFIYQ
. . ||. ..   ... |..||||.| | ||.|.|||.  .  |. . ...||..|. ||||. |.| . .|..| |.|.
lrlvrellen..lpgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvqtleqyrfvye

0051299 (Phosphotyrosine protein) phosphatases II 2-137 6e-34 113.2 In-house 106-280 (288) alignment
Range on Protein: 2-137
Range on HMM: 106-280/288.0
ADFWQMVWETGSGHIVMVNDDQKNKE--------------------------------------------TAPPSTREISHYQFTSWKEKTTPN-VALFV
.|||.|||| .. .|||... . ..                                             . .  .|.. |...|.| .  .|. . |..
edFWrmvweqnvrvIvmltklvelgrekcaqYwplggsltygditvtllseevlddytvrtlevtnldlldgdgesrtvthfhytnwpdhgvpdspelll

GFVVASREVSKkyeqEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEESktSVVDLFEVAKRLRQARCGIISSLQHYNFIYQ
 |. . |.. .     .. ||.||||.| | ||.|.|||. ..  |.    .||..|. ||||. |.|.. ....| |.|.
dflrlvrkala....sgggpvvVHCsaGvgRtgtfialdllleqleke..ggvdvleavkrlreqRpgmvqtpeqyrfvye

0050432 (Phosphotyrosine protein) phosphatases II 2-137 6.1e-34 113.1 In-house 122-293 (308) alignment
Range on Protein: 2-137
Range on HMM: 122-293/308.0
ADFWQMVWETGSGHIVMVNDDQKNKE-------------------------------------------TAPPSTREISHYQFTSWKEKTTPN-VALFVG
.|||.|||| .. .|||... . |.                                            .  . .|.. |...|.|..  .|. .. .. 
edFwrmvweqnvrvIvmLtklvengrekcaqYwplelgggsleygkftvtllseevlddytvrtleltnlgdgesrtvthfhytnWpdhgvPpspeilld

FVVASREVSkkyeqeKDAPVIVHCSDGQGFTGVFVALDIGVRSHEESktSVVDLFEVAKRLRQARCGIISSLQHYNFIYQ
|. . |..       .. |..||||.| | ||.|.|||. ..  |.     ||.||. |.||. |.| . ....| |.|.
flelvrksl......pggpivVHCsaGvGRtGtfialdllleqleke..ggvdvfeavkklReqRpgmvqtpeqylflyr

0036941 (Phosphotyrosine protein) phosphatases II 2-137 3.8e-33 110.5 In-house 92-271 (297) alignment
Range on Protein: 2-137
Range on HMM: 92-271/297.0
ADFWQMVWETGSGHIVMVNDDQKNKE--------------------------------------------TAPPSTREISHYQFTSWKEKTTPN-VALFV
.|||.|||| .. .|||....  .                                              |  . .|.. |...|.| .  .|. .| ..
edFWrmvweqnvtvIvmltelvelgrekcaqywpleegesltygdftvtllsvevvllddytlrtlevtdtgngesrtvthfhytgwpdhgvpespasll

GFVVASREVSKKYeqEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEES-KTSVVDLFEVAKRLRQARCGIISSLQHYNFIYQ
 |. . |.| |..   .. ||.||||.| | .|.|.|.|. ..  |.. |.  ||..|. | ||. |.|.. .|..| |.|.
dfielvrkvlkll..psggpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflye

0047943 (Phosphotyrosine protein) phosphatases II 2-137 4.4e-33 110.3 In-house 91-266 (273) alignment
Range on Protein: 2-137
Range on HMM: 91-266/273.0
ADFWQMVWETGSGHIVMVNDDQKNKET-------------------------------------------APPSTREISHYQFTSWKEKTTP-NVALFVG
.|||.|||| .. .|||..... ..                                               . .|.. |...|.| .  .| ... .. 
edfwrmvweqnvrviVmLtelvelgrekcaqYwpleggelsltygkftvtllseetkddytvrtleltnlgtgesrtvthfhytgwpdhgvppsleslle

FVVASREVSKKYEQEkdAPVIVHCSDGQGFTGVFVALDIGVRSHEESktSVVDLFEVAKRLRQARCGIISSLQHYNFIYQ
|. . |.. ... ..   ||.||||.| | ||.|.|||. ..  |.     ||..|. |.||. |.|.. ....| |.|.
fielvrkalealpsn..gpvvVHCsaGvgRtgtfialdllldqleke..ggvdvleavkllrsqRpgmvqtpeqyrflye

0040438 (Phosphotyrosine protein) phosphatases II 2-137 2.4e-32 107.9 In-house 100-270 (317) alignment
Range on Protein: 2-137
Range on HMM: 100-270/317.0
ADFWQMVWETGSGHIVMVNDDQKNK----------------------------------------ETAPPSTREISHYQFTSWKEKTTP-NVALFVGFVV
.|||.|||| |...|||...   ..                                         .  . .|.. |...|.| . ..| .  |.. |. 
edFwrmvweqgvtvivmLteleelgrekcaqYwplgetltygdftvtllseeelagitlrtlevedlgdsesrtvthfhytgWpdhgvppspdllldfle

ASREVSKkyeqEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEESKtsVVDLFEVAKRLRQARCGIISSLQHYNFIYQ
| ||. .    ... ||.||||.| | ||.|.|... ..  |. .   ||..|. |.||..|.|.. ....| |.|.
avreale....dpggpvlVHCsaGvgRtGtfiaaylmleqlekeg..gvdveeavkelreqRpgavqtpeqyrflyd

0045450 (Phosphotyrosine protein) phosphatases II 2-137 2.7e-32 108.2 In-house 121-298 (307) alignment
Range on Protein: 2-137
Range on HMM: 121-298/307.0
ADFWQMVWETGSGHIVMVNDDQKNKET------------------------------------------APPSTREISHYQFTSWKEKTTP-NVALFVGF
.|||.|.|| |...|||....  ..                                                .|.. |...|.| . ..| ... .. |
edFwrmlweqgvtvivmltelvelgrekcaqywPdegeeltygnftvtllseehldgytvrtlevtdldgtgesrtvthfhytgwpdhgvppsfeelldf

VVASREVSKKYeqEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEESKTSV-VDLFEVAKRLRQARCGIISSLQHYNFIYQ
. . |.. ...   |. ||.||||.| | ||.|.|...  | .|. .|   |||.|. |.||. |.|.. ....| |.|.
ieevrkaleel..pkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrflye

0043336 (Phosphotyrosine protein) phosphatases II 2-137 1.8e-31 105.0 In-house 102-271 (278) alignment
Range on Protein: 2-137
Range on HMM: 102-271/278.0
ADFWQMVWETGSGHIVMVNDDQKNKE---------------------------------------TAPPSTREISHYQFTSWKEKTTP-NVALFVGFVVA
.|||.|||| |. .|||....  ..                                        .  . .|.. ||....| . ..| ...|.. |. |
edFwrmvwelgvttivmLtelvelgrvkcaqYwpggsltygdftvtllkeehlddytvrtlevtnlgdgesrtvthyhylgwpdhgvpeslsllldflka

SREVSKkyeqEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEESKtsVVDLFEVAKRLRQARCGIISSLQHYNFIYQ
 ||. .     .. ||.||||.| | ||.|.||.. ..  |  .   |||.|. |.||. |.|.. ....| |.|.
vreale....dsngpvlVHCsaGvgRTGtfialyllleqlekeg..gvdleeavkelreqRpgavqtpsqyrflye

0039614 (Phosphotyrosine protein) phosphatases II 2-137 4.3e-31 103.9 In-house 115-283 (297) alignment
Range on Protein: 2-137
Range on HMM: 115-283/297.0
ADFWQMVWETGSGHIVMVNDDQKNKE------------------------------------TAPPSTREISHYQFTSWKEKTTP-NVALFVGFVVASRE
.|||.|||| |. .|||...   ..                                     |    .|.. |.|.|.| . ..| ...|.  |. . ||
edFwrmvweqgvtvivmLtklvelgrkcaqywpeeggtygdftvtllkvehldgytvrtlevtnngesrtvthfqytgwpdhgvppslellleflelvre

VSKKYeqEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEESktSVVDLFEVAKRLRQARCGIISSLQHYNFIYQ
. ...  .|. ||.||||.| | ||.|.|... ..  |.     ||..|. |.||..|.|.. ....| |.|.
alael..pkggpvlVHCsaGvgRtGtfiaaylmleqleke..ggvdvleavkelreqRpgavqtpsqyrflyd

0045098 (Phosphotyrosine protein) phosphatases II 2-137 7.5e-30 99.7 In-house 78-266 (278) alignment
Range on Protein: 2-137
Range on HMM: 78-266/278.0
ADFWQMVWETGSGHIVMVNDDQKNK--------------------------------------------ETAPPSTREISHYQFTSWKEKTTPNVALFVG
||||.|.|| |. .|||... . ..                                            | .   .|.. |.....| . ..|.  .   
adfwrmlwelgitvivmltelvelgrekcaqywpeggsltygdftvtllseevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilks

FVVASREVSKKYE------------QEKDAPVIVHCSDGQGFTGVFVALDIGVRSHeeskTSVVDLFEVAKRLRQARCG-IISSLQHYNFIYQ
|  . ... . ..            .... ||.|||| | | ||..||...  .       ..|||.|. | ||. |.| .. .|..|.|.|.
flellefirealkllaslllsslllldsggpvlVHCsaGvgRtGtlvaaylmlell....eggvdlleavkelrsqRpglavqnleqyrflye

0042113 (Phosphotyrosine protein) phosphatases II 2-137 1.6e-29 98.5 In-house 66-237 (245) alignment
Range on Protein: 2-137
Range on HMM: 66-237/245.0
ADFWQMVWETGSGHIVMVNDDQKNKET----------------------------------------APPSTREISHYQFTSWKEKTTPN-VALFVGFVV
.|||.|.|| |. .|||....  ..                                            . .||. ||....| . ..|. ..|.. |. 
edfwrmlwelgittivmLteeeelgrvkcaqywplgesltygdftvtllseehlddytvrtlevtnlgddesrevihyhylpwpdhgvpdllellldfle

ASREVSKKyeqEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEesKTSVVDLFEVAKRLRQARCGIISSLQHYNFIYQ
. |.. ..    .. ||.||||.| | ||.|.|... ..  |  |.  |.|.|. |.||. |.|.. ....| |.|.
fvrkalae...dsngpvlVHCsaGvgRtGtfiaaylmleqle..kelgvsleeavkelrsqRpgavqtpsqyrflye

0040439 (Phosphotyrosine protein) phosphatases II 2-137 1.9e-29 98.5 In-house 68-240 (249) alignment
Range on Protein: 2-137
Range on HMM: 68-240/249.0
ADFWQMVWETGSGHIVMVNDDQKNK----------------------------------------ETAPPSTREISHYQFTSWKEKTTP-NVALFVGFVV
.|||.|.|| |...|||..... ..                                         .  ...|.. |.|.|.| .  .| ... .. |. 
edfwrmlwelgitvivmLtslvelgrekcaqywplggsleygdftvtllsvevkddytvrtleltnlydgesrtvlhiqytdwpdhgvppsfedlldfie

ASREVSKKYeqEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEesKTSVVDLFEVAKRLRQARCGIISSLQHYNFIYQ
| |.. ...  .|. ||.||||.| | ||.|.|... ..  |  |.  |||.|. | ||..|.|.. ....| |.|.
avrkaleel..pkggpvlVHCsaGvgRtGtfiaaylmleqle..kelgvdleeavkllrsqRpgavqnpeqyrflye

0037934 (Phosphotyrosine protein) phosphatases II 2-137 1.1e-26 89.4 In-house 58-236 (243) alignment
Range on Protein: 2-137
Range on HMM: 58-236/243.0
AD----FWQMVWETGSGHIVMVNDDQKNKET---------------------------------------APPSTREISHYQFTSWKEKTTPN-VALFVG
.|    ||.|.|| |...|||..... ..                                         ... ||.. ||....| . ..|. .. .. 
eddlasfwrmlwelgitvivmltelvElgrekcaqywpgevtygdftvtllseehlddytvrtlllenldlddltrlvihyhylpwpdhgvPdspedlld

FVVASREVSKKY----EQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHeesktSvVDLFEVAKRLRQARCG-IISSLQHYNFIYQ
|. . ||. ...       .. ||.|||| | | ||...|...  .       . |||.|. |.||. |.| .. ....| |.|.
fldevrefieellsllaldsggpvlVHCsaGvgRtGtliaaylmllll.....g.vdleeavkllreqRpgkavqtpsqyrflye

0041856 (Phosphotyrosine protein) phosphatases II 2-137 9e-23 76.2 In-house 48-165 (182) alignment
Range on Protein: 2-137
Range on HMM: 48-165/182.0
ADFWQMVWETGSGHIVMVNddqKNKETAPPSTREISHYQFTSWKEKTTPNVALFVGFVVASREvskkyeqeKDAPVIVHCSDGQGFTGVFVALDIGVRSh
|||..|..| | ..||...        .   .|.. .|....|   ..|..  .. |. . .|        .. ||.|||| | | ||..||...  .  
adflrmlkelgittivnlt...eelywpellerlgiqylylpwpDhgvpdldelldfieevle........eggpvlVHCsaGvgRtgtlvaaylmkkl.

eesktSvVDLFEVAKRLRQARCGIISSLQHYNFIYQ
     . |.|.|. | .|..|.|.. ....| |...
.....g.vsleeavklvrsrRpgmvitpnqyfflql

0051429 (Phosphotyrosine protein) phosphatases II 2-137 2.3e-19 65.6 In-house 36-219 (272) alignment
Range on Protein: 2-137
Range on HMM: 36-219/272.0
ADFWQMvWETGSGHIVMVNDDQ---KNK----------------------ET----------------------------APPSTREISHYQFTSWKEKT
||||.. .| |  .||.. ..    ..|                       .                             .  .||. |...|.|    
adfwrl.kelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseellldyilrellltlllsagearevmhlhytdwpdhg

TPN--VALFVGFVVAsrevskkyeqekDAPVIVHCSDGQGFTGVFVALDIGVrsHEESKTSVVD--------LFEVAKRLRQARCGIISSLQHYNFIYQ
.|   .  .. .. .            . ||.|||| | . ||..|||.. .  .  |.. .||        |.|. ..||..| |.. . ..| |.|.
vpqeallellellld............ggpvlvHCsaGkdRTGtvvalllll..lgvsletivddYlltnlyleeaveelraqrpgavqteeqylflye

0044763 (Phosphotyrosine protein) phosphatases II 2-137 3.1e-17 58.2 In-house 38-165 (178) alignment
Range on Protein: 2-137
Range on HMM: 38-165/178.0
ADFWQMVWETGSGHIVMVNDDQKN---KETAPPSTREISHYQFTSWKEKTTPN-VALFVGFVVASREVSkkyeQEKDAPVIVHCSDGQGFTGVFVALDIG
||......| | .|||...... .   |. .   ...  .|... .   ..|.  . |  || . .|.     .||. ||.|||| | | .|..||... 
addlellkelgithivnlteelelgflkcdpywpeeagiqylhipipDhgvpdllehflefvefieeal....dekggpvlVHCsaGvgRsgtlvaaylm

VRSheesktSVvDLFEVAKRLRQARCgIISSLQHYNFIYQ
 .       .. .|.|. ...|..|. |. .  .....|.
kkl......gl.sleeaielvrerRp.ivpnpgqlrqLye

0049772 (Phosphotyrosine protein) phosphatases II 3-136 4.4e-16 55.0 In-house 99-273 (314) alignment
Range on Protein: 3-136
Range on HMM: 99-273/314.0
DF----------WQMV--WETGSGHIVM---------------------VND----------------DqknKET--APPSTREISHYQFTSWKEKTTPN
||          |.||  ..  .  |||                      ..                    .|.  ..  .|.. .|  . .   ..| 
dfreepvlyyngwrmvlrgdlnvrdivmsrdevladelsrLdaAlgKtpllildgngneptaadlellk...eelydpelferlgikylripvpDgsapl

VALFVGFVVASREVskkyeqEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEesktsvVDLFEVAKRLRQARC-----GIISSLQHYNFIY
 . |  |. . .|.      .|. ||.|||..| | ||.||.... .. .       |.| |. ...|..|      | | .|..| ||.
ledfdeflefieea......dkggpvlvHCkaGkgRtgtfvvaaylmkllg......vsleealedvrlkRpinpnpgfieqleqyefil

0036282 (Phosphotyrosine protein) phosphatases II 4-137 1.4e-24 82.2 In-house 28-164 (174) alignment
Range on Protein: 4-137
Range on HMM: 28-164/174.0
FWQMVWETGSGHIVMVNDDQKNK---------ETAPPSTREISHYQFTSWKEKTTPNVALFVGFVVASREVSKKyeqEKDAPVIVHCSDGQGFTGVFVAL
||.|..| |. ..||... . ..         |.    .|.. .|... |   ..|... .  || . .|. ..    .. ||.|||| | | ||..||.
fwemlkelgittvvmlleekelglykcinywpelredlerlgiqylylpwpDhgvpdlsillefvkfveealse...dpggpvlVHCsaGvgRtGtlvaa

DIGVRSHEeskTSVVDLFEVAKRLRQARCGIISSLQHYNFIYQ
..  | ..   .|.|| ... ..||. |.|.. . ..| |.|.
ylmlrgll...eslvdaldlvrelRlqrpgmvqtpsQyrflyy

0048076 (Phosphotyrosine protein) phosphatases II 7-137 1.1e-14 49.8 In-house 24-137 (145) alignment
Range on Protein: 7-137
Range on HMM: 24-137/145.0
MVWETGSGHIVMVnddqknKETAPPSTREISHYQFTSWKEKTTPNV-ALFVGFVVASREVSKKyeqekDAPVIVHCSDGQGFTGVFVALDIGVRsheesk
. .. | .... .        . .  .|.. .|....|   ..|.  .|.  |. . .|. |.     . ||.|||| | | ||..||...  .      
llkdlgittvlnl......tselellerlgiqylylpwpDhgvpdllellleflefieealke.....ggpvlVHCsaGvgRtgtlvaaylmll......

TSvVDLFEVAKRLRQARCGIISSLQHYNFIYQ
 . |.|.|. ...|..| |.. . ....|.|.
lg.vsleealelvrsqrpgavpnpgqlrflye

0048179 (Phosphotyrosine protein) phosphatases II 9-137 2.4e-14 48.8 In-house 26-139 (144) alignment
Range on Protein: 9-137
Range on HMM: 26-139/144.0
WETGSGHIVMVNDDqknkETAPPSTREISHYQFTSWKEKTTPNV-ALFVGFVVASREVskkyeQEKDAPVIVHCSDGQGFTGVFVALDIGVrsheesKTS
.. | .... ....       .  .||. .|....|    .|.  .|.  |. . .|.     .|.. ||.|||| | | ||..||... .      |  
kklgittvinltee....yepefleregiqylhlpwpDhgvpdllellleflefieea.....leeggpvlVHCsaGvgRtgtlvaaylmk......klg

vVDLFEVAKRLRQARCGIISSLQHYNFIYQ
 ..|.|. ...|..|.|.. . ....|...
.lsleealalvrsrrpgavpnpgqlrfLle

subfamily_Auxilin_pd Subfamily Auxilin 13-120 2.3e-07 23.7 In-house 48-147 (166) alignment
Range on Protein: 13-120
Range on HMM: 48-147/166.0
SGHIVMVNDDQKNKETAPPSTReISHYQftsWKEKTTPNVALFvgfVVASREVSKKYEQEKDAPVIVHCSDGQGFTGVFVA-LDIGVRSHEESkTSVVDL
... ...|  |....||..|.| .....   | .. .||.  .   |  .|.. .  ....   |.||| ||.  ..| |. | . .|  .|.  | |.|
pekylvynlsqrtyrtaklssr.vveag...wparraPnLesl...vevcrnlyswlkkdpknvvvvhckDGraasavlvsallvfcrllsep.esavrl

FEVaKRLRQ
| | ||| .
fsv.krlpi

subfamily_Cele-PTP-7_pd Subfamily Cele-PTP-7 24-131 1.3e-09 31.9 In-house 178-276 (302) alignment
Range on Protein: 24-131
Range on HMM: 178-276/302.0
KNKETAPPSTREISHYQFTSWKEKTTPNVALfvgfvvASREVSKKYEQEKdAPVIVHCSDGQGFTGVFVALDIGVRSHeeSKTSVVDLFEVAKRLRQARC
||...     . ..  .|..| .. .|. |       .. .. |  |  |   |.|||| | | || .||.  |.     ||  | || .. . .|| | 
knekkkkkvkktvdilafsawpdhGapkeay......taldilkfcesyk.knvlvhcsaGvGrtGtlvaikyGiqlc..skkkvtdllsivlpvrqcry

GIISSLQH
| . . | 
Gavqdeqq

subfamily_Nvec-PTP-3_pd Subfamily Nvec-PTP-3 25-137 8e-82 268.2 In-house 85-197 (198) alignment
Range on Protein: 25-137
Range on HMM: 85-197/198.0
NKETAPPSTREISHYQFTSWKEKTTPNVALFVGFVVASREVSKKYEQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEESKTSVVDLFEVAKRLRQARCG
|. |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
nnttappstreishyqftswkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcg

IISSLQHYNFIYQ
|||||||||||||
iisslqhynfiyq

subfamily_Sponge-PTP11_pd Subfamily Sponge-PTP11 25-137 4.2e-20 66.8 In-house 170-277 (290) alignment
Range on Protein: 25-137
Range on HMM: 170-277/290.0
NKETApPSTREISHYQFTSWKEKTtpNVALFVGFVVASREVSKKYEQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEesKTSVVDLFEVAKRLRQARCG
||..|  ..... .||.|.|...   .|.   . ... .|. |.  .. . ...|||||. | ..||.|.....   .  .. |.|.|.| |..|. . |
nknsa.gakqsvtqyqitnwdstg..kvtnpqtillvieemyktqrkrgntsivvHCSdtvgrsavfcaaattinkck..tegvidvfqvlksqRiqkpg

IISSLQHYNFIYQ
 . . |.|..|.|
svqtvqqyqgifq

subfamily_Cele-PTP-15_pd Subfamily Cele-PTP-15 25-136 4.3e-08 27.5 In-house 158-263 (285) alignment
Range on Protein: 25-136
Range on HMM: 158-263/285.0
NKETAPPSTREISHYQFTSWKEKTTPNVALFVgfVVASREVsKKYeQEKDAPVIVHCSDGQGFTGVFVALDIG-VRSHEESKtsvVDLFEVAKRLRQARC
| | |      . | |   | .. .|. |  .  .   . | ||  . |. |. |||| | | |  || .|   .|  |. .   ...... . .|  | 
ntedasseplymnhvqvpwwpdqlapedarpm..ielykwv.kkv.npkekpicvhcsagvgrtatfvgidyatirimenpn...iemldivremramrf

GIISSLQHYNFIY
  . |  .. |.|
qavqshmqflfly

subfamily_Ptp69D_pd Subfamily Ptp69D 26-137 1.2e-21 72.2 In-house 174-280 (307) alignment
Range on Protein: 26-137
Range on HMM: 174-280/307.0
KETAPPSTREISHYQFTSWKEKTTPNVALfvGFVVASREVSKKYEQEkDAPVIVHCSDGQGFTGVFVALDIGVRSHEESKtsVVDLFEVAKRLRQARCGI
. .  . .|..  |..|.||. . |.||   | .   ..| . |...  .|..|||| | | .|.|||||. .   .. .   ||.||. | ||. |  .
esgevedsrkvvqyhytgWkDskvPevar..gllklieqvrelykln.rsPivvhCsaGvgrsgifvaldsllqqlkaed..kvdifetvkdLrsqRnll

ISSLQHYNFIYQ
. ||. | |.|.
vqsleqYvflyr

subfamily_PTPRG_pd Subfamily PTPRG 26-137 7.9e-20 65.6 In-house 174-281 (563) alignment
Range on Protein: 26-137
Range on HMM: 174-281/563.0
KETAP-PSTREISHYQFTSWKEKTTPNVALFVGFVVASREVSKKyeqEKDAPVIVHCSDGQGFTGVFVALDIGVRshEESKTSVVDLFEVAKRLRQARCG
|..    . ... .|..|.| ....|. .|.|   |  .. ..|   ..  |..|||| | | ||....||  ..  .  . ..|..|...|..|  |  
kkkkqcdteklvrqyhytkWPdhgvPehslpvLifvkkssaank...aeaGPivvHcsaGvgrtGtyivldtllk..qiqqenavnvfgflkhiraqRnf

IISSLQHYNFIYQ
.. .   | |...
lvqteEqYiflhd

subfamily_PTPRA_pd Subfamily PTPRA 27-137 8e-19 62.7 In-house 184-289 (330) alignment
Range on Protein: 27-137
Range on HMM: 184-289/330.0
ETAPPSTREISHYQFTSWKEKTTPNVAlfVGFVVASREVSKKYEQEKDaPVIVHCSDGQGFTGVFVALDIGVRS-HEEsktSVVDLFEVAKRLRQARCGI
.|   ..| .. . |||| .   |  .  .| .   ..| |. .|. . |..|||| | | || |..||  .   . |    .||.||. ||||. |. .
atrekksrlvrqfhftswPdvGvPfep..iGmlkllkkvkklnqqsag.pivvhcsaGvGrtGtfivldavlervkae...rkvdvfefvkrlrlqrpqm

ISSLQHYNFIYQ
. ... |.|||.
vqtdeqyefiyk

subfamily_Anemone-PTP-3_pd Subfamily Anemone-PTP-3 28-137 2.7e-81 266.5 In-house 89-198 (199) alignment
Range on Protein: 28-137
Range on HMM: 89-198/199.0
TAPPSTREISHYQFTSWKEKTTPNVALFVGFVVASREVSKKYEQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEESKTSVVDLFEVAKRLRQARCGIIS
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
tappstreishyqftswkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiis

SLQHYNFIYQ
||||||||||
slqhynfiyq

Y_phosphatase Protein-tyrosine phosphatase 28-137 5.1e-25 83.6 Pfam-A 126-231 (235) alignment
Range on Protein: 28-137
Range on HMM: 126-231/235.0
TAPP-STREISHYQFTSWKEKTTP-NVALFVGFVVASREVSkkyeQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEESKTsvVDLFEVAKRLRQARCGI
.. .  .||......|.|.....| ..  .. .. . .. .    ..|..||.||||.| | ||.|||||| ... |. ..  ||.... |.||. |.|.
kkeesekrevkqlhytnWpdhgvpespkslldlirkveksk....eaksgpvvVhCsaGvgRtgtfvaldilleqleaeee..vdvlqivkelRkqRpgm

ISSLQHYNFIYQ
..||. | |.|.
vqsleqYiflyk

Y_phosphatase Protein-tyrosine phosphatase 28-137 5.1e-25 83.6 In-house 126-231 (235) alignment
Range on Protein: 28-137
Range on HMM: 126-231/235.0
TAPP-STREISHYQFTSWKEKTTP-NVALFVGFVVASREVSkkyeQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEESKTsvVDLFEVAKRLRQARCGI
.. .  .||......|.|.....| ..  .. .. . .. .    ..|..||.||||.| | ||.|||||| ... |. ..  ||.... |.||. |.|.
kkeesekrevkqlhytnWpdhgvpespkslldlirkveksk....eaksgpvvVhCsaGvgRtgtfvaldilleqleaeee..vdvlqivkelRkqRpgm

ISSLQHYNFIYQ
..||. | |.|.
vqsleqYiflyk

subfamily_Anemone-PTP-6_pd Subfamily Anemone-PTP-6 28-137 4.7e-21 70.2 In-house 169-274 (318) alignment
Range on Protein: 28-137
Range on HMM: 169-274/318.0
TAPPSTREISHYQFTSWKEKTTPNVAlfVGFVVASREVSKKYEQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEESKtsVVDLFEVAKRLRQARCGIIS
|   ..|..  |..||| .. .|. .  ....   |.|||  ....  |..|||| | | ||||.|.|| ..  .. .  .||.|.. |.||. |  .. 
teeeesrqvrqyhytsWpdegvpesg..aslldlvrqvskaqqksgagpivvhCsaGvGrtGvfiavdillerikaea..lvDvfqtvkqlreqrnlmvq

SLQHYNFIYQ
  . |.|||.
tedqyefiyd

subfamily_Cele-PTP-18_pd Subfamily Cele-PTP-18 29-137 2.7e-06 21.4 In-house 181-281 (305) alignment
Range on Protein: 29-137
Range on HMM: 181-281/305.0
APPSTREISHYQFTSWKEKTTPNVALFVGFVVASREVSKkyeqekdAPVIVHCSDGQGFTGVFVALDIGVRSHeESKTSVVDLFEVAKRLRQARCGIISS
.  ..| ..|| .  | ..  |   | .  ...   .||        |..|||| | | ||  | |.  .     .   . |   . ...|. |   | .
pgekarkvthyhwidwpdrgvpaadlailellekarpsk.......gpivvhcsagigrtgsvvmleyildql.lagqiiedtdkilqkireqrnnsiqt

LQHYNFIYQ
 . | |..|
daqylfvhq

subfamily_PTPRD_pd Subfamily PTPRD 30-137 1.3e-23 78.5 In-house 173-275 (564) alignment
Range on Protein: 30-137
Range on HMM: 173-275/564.0
PPSTREISHYQFTSWKEKTTPNVAlfVGFVVASREVSKKYeQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEEskTSVVDLFEVAKRLRQARCGIISSL
  ..||. ...|||| ..  |. |   ...   |.|..   ...  |..|||| | | ||.|...|. ..  .|    .||.... |.||. |  .. . 
ssesreVrqFhFtsWPdhgvpesa..tslLdlirkvraln.epdagPivVhCSaGVGRTGtfividamlerike..ektvDiyqyvkalrkqRnamVqte

QHYNFIYQ
. | ||..
eQYiFihe

subfamily_CG7180_pd Subfamily CG7180 30-137 2.1e-22 74.1 In-house 176-284 (296) alignment
Range on Protein: 30-137
Range on HMM: 176-284/296.0
PPSTREISHYQFTSWKE-KTTPNV-ALFVGFVVASREVSKKY-EQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEesKTSVVDLFEVAKRLRQARCGII
   || . ..|.| |.  .  | . . .. ..   | . .|  |... .||.|..|||.. .||..|.|. .   |  |.  ||.|| .|.||. | ...
kaetRivklfqlteWeledkvPlstnalielrrrvrlwrekvdedpeegPvvvvssdGasRsGvylaidanlelve..keeevdvFeavktlrrsRpqLv

SSLQHYNFIYQ
 . ..| .||.
enveeYkyiYd

subfamily_PTPN6_pd Subfamily PTPN6 30-137 5e-20 66.7 In-house 182-291 (306) alignment
Range on Protein: 30-137
Range on HMM: 182-291/306.0
PPSTREISHYQFTSWKEKTTPNVAL-FVGFVVASREVSKKYEQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEESKTSV-VDLFEVAKRLRQARCGIIS
  ..||. .|.|.|| .. .|.    .. |.   .. ... |...  |..||||.| | || |. .|| ..  |.... . .|. .. | .|. | |.. 
kkeerevfqyhfksWPdhgvpkdpgavLdfledvnrkqeeleeaeagpivvhCsaGiGRtGtfiviDillkliekkgldadidiqklvksvreqrsglvq

SLQHYNFIYQ
  | |.|.|.
teqqykfvyk

DSPc_SM00195 31-137 2.1e-23 78.4 In-house 155-256 (263) alignment
Range on Protein: 31-137
Range on HMM: 155-256/263.0
PSTREISHYQFTSWKEKTTP-NVALFVGFVVASREVSKKYeqekDAPVIVHCSDGQGFTGVFVALDIGVRSHEESKTsvVDLFEVAKRLRQARCGIISSL
  ||.. .||...|... .| .   .. .. | .. ...     ..|..||||.| | ||.||..|| ... || |.  ||.||. |.||. |.|....|
eetrkvtqyqyknWpdhgvpdstksvlellravkksksts....sgpivVhCsaGvgRtgtfvtidiilskleeekk..vdifeivkelRkqRpgmvqtl

QHYNFIYQ
..| |||.
eqYlfiye

PTPc_SM00194 31-137 2.1e-23 78.4 In-house 155-256 (263) alignment
Range on Protein: 31-137
Range on HMM: 155-256/263.0
PSTREISHYQFTSWKEKTTP-NVALFVGFVVASREVSKKYeqekDAPVIVHCSDGQGFTGVFVALDIGVRSHEESKTsvVDLFEVAKRLRQARCGIISSL
  ||.. .||...|... .| .   .. .. | .. ...     ..|..||||.| | ||.||..|| ... || |.  ||.||. |.||. |.|....|
eetrkvtqyqyknWpdhgvpdstksvlellravkksksts....sgpivVhCsaGvgRtgtfvtidiilskleeekk..vdifeivkelRkqRpgmvqtl

QHYNFIYQ
..| |||.
eqYlfiye

subfamily_Anemone-PTP-2_pd Subfamily Anemone-PTP-2 31-137 1.8e-21 71.7 In-house 182-284 (298) alignment
Range on Protein: 31-137
Range on HMM: 182-284/298.0
PSTREISHYQFTSWKEKTTPNVALFVgfVVASREVSKKYEQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEesKTSVVDLFEVAKRLRQARCGIISSLQ
 ..||. . .|||| .|..|..|  |  .   |.| .. .| ...||||.||.| | .| |.|.|  .   .  | .|||.|.| |.||. |.|.. . .
ekerevrqlhftsWpdkgvpenatsv..ldllrkvrasqqqagnkpvivqCsaGvgRsGtfiaidsvlervk..keqvvDvfqvvkvlRkkrpgavqtee

HYNFIYQ
.| |||.
qYvfiye

subfamily_Urchin-PTP-5_pd Subfamily Urchin-PTP-5 31-137 1.7e-19 65.1 In-house 174-278 (297) alignment
Range on Protein: 31-137
Range on HMM: 174-278/297.0
PSTREISHYQFTSWKEKTTPNVALFVGFVVASREVSKKYEQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEesKTSVVDLFEVAKRLRQARCGIISSLQ
 ..| .  |||..| .|. ..      ..    || |...|....|..|||. | | |||....|  |   .  ..  ||.|.. |.||| |  ..   .
karrvvkqyqfveWPdkaverkdsassllklisevrkdfsqnaegPllvhclaGvGrtgvlltidsvvaeak..rekevdifglvkklrqerpylvqtke

HYNFIYQ
.|.|.|.
qykfvyv

subfamily_PTPN3_pd Subfamily PTPN3 31-135 5.2e-17 56.7 In-house 168-267 (280) alignment
Range on Protein: 31-135
Range on HMM: 168-267/280.0
PSTREISHYQFTSWKEKTTPNV-ALFVGFVVASREVSkkyeQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEESKTsvVDLFEVAKRLRQARCGIISSL
   |.| . |...| ... |.  | |. ||   |..     . |. ||.|||| | | |||...|.. .   |...   |   .. ...|. |  .. . 
keerkilqlqylaWpdhgvPddsadflefvervrklr....sgkeePvvvhCsaGigrtGvlilletalalieaaep..vypldivrtmrdqramlvqta

QHYNFI
. |.|.
sqykfv

subfamily_PTPN9_pd Subfamily PTPN9 31-136 5.2e-17 56.8 In-house 170-283 (297) alignment
Range on Protein: 31-136
Range on HMM: 170-283/297.0
PSTREISHYQFTSWKEKTTPNVAL-FVGFVVASRE--------VSKK-YEQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEEskTSVVDLFEVAKRLRQ
  .|...|.||.|| .  .|. |  .. .. . ||        ....   . .. |..|||| | | || |..||| .   ||  ...||..|. |.||.
eesrkvthfqflsWPdyGvPssaaslldvlekvrekqalavkelgdewkghpsgPPivvhcsaGiGrtGtfitldiclsrlee..vgtvdvvetvkllrt

ARCGIISSLQHYNFIY
 |   |   . |.| |
qrafsiqtpeqyefcy

subfamily_PTPN23_pd Subfamily PTPN23 31-137 1.3e-16 55.3 In-house 168-274 (288) alignment
Range on Protein: 31-137
Range on HMM: 168-274/288.0
PSTREISHYQFTSWKEKTTPN-VALFVGFVVASREVSKKYEQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHeESKTSVVDLFEVAKRLRQARCGIISSL
  ....|| |.||| |   |.    .. |. . ..  .. ... ..|..|||| | | ||||  .   ||   | .  ..|. .| .|||. |   ..  
davksvshlqltsWpelGvPasPetllqfldevesayeavqrksktPlvvhCsaGvgRtgvfalvyaavrel.ekgnglldiiqvvsrlreqRrfmvqek

QHYNFIYQ
....| |.
eqlkfsye

subfamily_PTPN13_pd Subfamily PTPN13 31-137 4e-16 54.1 In-house 163-263 (273) alignment
Range on Protein: 31-137
Range on HMM: 163-263/273.0
PSTREISHYQFTSWKEKTTPNVAL-FVGFVVASREVSKkyeqeKDAPVIVHCSDGQGFTGVFVALDIGVRSHEESKtsVVDLFEVAKRLRQARCGIISSL
  .||..| .|..| .  .|. |. .. ||   |.. .     . .|..|||| | | .|.....|. .   |  |   .|. |. ..||. | |.. . 
gesrevahlnfvkwPdhgvPssaaellqfvaevrrlqt.....dagPivvhcsaGiGrsGtlitidvvlglierdk..efdvkeivrklreqrqgvvqtk

QHYNFIYQ
. | |.|.
dqyifvyk

subfamily_PTPRN_pd Subfamily PTPRN 31-136 4e-15 50.3 In-house 184-285 (297) alignment
Range on Protein: 31-136
Range on HMM: 184-285/297.0
PSTREISHYQFTSWKEKTTPNVALfvGFVVASREVSKKYEQeKDAPVIVHCSDGQGFTGVFVALDIGVRSHEEsKTSVVDLFEVAKRLRQARCGIISSLQ
  || .. . | ||.|...|  |    ..   | | | |   . .|..|||||| | |||....|. .          .|.    . ||. | |.. . .
setrtvtqfhflswpeegvPasak..sllefrrkvnksyrG.rscpivvhcsdGaGrtGvyilidlvlnrllk.Gvkeidiaatlehlrdqrpglvktkd

HYNFIY
 ..|..
qfefal

subfamily_PTPN1_pd Subfamily PTPN1 31-136 7.6e-15 49.4 In-house 159-264 (290) alignment
Range on Protein: 31-136
Range on HMM: 159-264/290.0
PSTREISHYQFTSWKEKTTPNV-ALFVGFVVASREVSKKyeQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEESK-TSVVDLFEVAKRLRQARCGIISS
  ||||.|. .|.| . . |.  | |. |.   ||      ...  |...||| | | .| |. .|  .   |... .| ||. .|   ||. | |.|  
qetreilhfhyttwpdfgvpespaaflkflfkvresGsl..ssdvGpavihcsaGiGrsGtfclvdtclvliekkddlssvdikkvllelrkyrlGliqt

LQHYNFIY
 .  .| |
adqlrfsy

subfamily_Urchin-PTP-3_pd Subfamily Urchin-PTP-3 31-136 6e-14 46.9 In-house 175-281 (325) alignment
Range on Protein: 31-136
Range on HMM: 175-281/325.0
PSTREISHYQFTSWKEKTTPNV-ALFVGFVVASREVSKKYEQ--EKDAPVIVHCSDGQGFTGVFVALDIGVRshEESKTSVVDLFEVAKRLRQARCGIIS
  || .  .|. ||..  ...  | .. ..    .||..     .  .|..||||.| | ||||..|   .   .  . | ||.|.. |.||. |  .. 
GetrsvkqfqlqswddmGvqkrpatlisilqlvkavservtantkastpilvhcsaGvGrtGvfislysala..kvieesrvdifgfvkklrkdrpsmve

SLQHYNFIY
.   | .||
tvdqyiliy

subfamily_Sponge-PTP8_pd Subfamily Sponge-PTP8 32-136 1.6e-24 81.6 In-house 176-276 (305) alignment
Range on Protein: 32-136
Range on HMM: 176-276/305.0
STREISHYQFTSWKEKTTPNVAlfVGFVVASREVSKKYEQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHeeSKTSVVDLFEVAKRLRQARCGIISSLQH
 .| ...||.|.| ..  |. |    ..   ..| |.....|. |..||||.| | ||||.|.|| .      |  |||.||| |.||. | .....|..
esrtvlqyqltdWPdhGvpqfa..tsllslikrvqkdqkkdkgvpllVhCsagvgRtGvfiavdialerl..kkEevvdvfevlkqlRskrmkmvqtldq

YNFIY
|.|..
Yvflh

subfamily_Anemone-PTP-5_pd Subfamily Anemone-PTP-5 32-137 2.6e-24 80.9 In-house 176-277 (319) alignment
Range on Protein: 32-137
Range on HMM: 176-277/319.0
STREISHYQFTSWKEKTTPNVALFVgfVVASREVSKKYEQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHeeSKTSVVDLFEVAKRLRQARCGIISSLQH
 |||..|.|.|.| ..  |. |. .  .   ... |  |.... |..||||.| | || |..||. .     .. .|.|.|....|||  |  ...  . 
etRevkhfqyteWpdhdvPekatsl..ldllkrirksrektqsgPivvhCsaGvGRtGtfivldamlerv..keegvlDvfstvsrlRtqRnimvqrpeq

YNFIYQ
|.|||.
Ykfiye

subfamily_Choan-PTP-2_pd Subfamily Choan-PTP-2 32-137 3.3e-21 70.5 In-house 150-258 (270) alignment
Range on Protein: 32-137
Range on HMM: 150-258/270.0
STREISHYQFTSWKEKTTPNVAL----FVGFVVASREVSKKYEQEKD-APVIVHCSDGQGFTGVFVALDIGVRSHEESKtsVVDLFEVAKRLRQARCGII
..|.. |.....| ... |. .         .   |.| .  .. ..  |..||||.| | ||...||||.||  ||.|   ||. .. ..||. |. ..
eerrlvHfwyntWpdhgvpreedsslstdqllkmlravrrsekeldkaePllvHcsaGvgRtGtlialDiavrlLeetk..kvdvlaiieelRkdRmalv

SSLQHYNFIYQ
.  ..|.|.|.
qhpeqyeflyk

subfamily_PTPRK_pd Subfamily PTPRK 32-137 4.1e-21 70.1 In-house 171-271 (314) alignment
Range on Protein: 32-137
Range on HMM: 171-271/314.0
STREISHYQFTSWKEKTTPNVAlfVGFVVASREVSKKYEQeKDAPVIVHCSDGQGFTGVFVALDIGVRSHEesKTSVVDLFEVAKRLRQARCGIISSLQH
 .||. ..||..| .  .|. |   |..   |.| |. |. .. ...|||| | | ||.|.|.|| .   |  . .|||.|...| ||. .  ..   . 
eirevrqfqflgWpdhdvPvsa..tgllklvrrvkksqee.eaGrivvhCsaGaGrtGtfiaidivldmie..regvvdvfnavktlrsrkvnmveteeq

YNFIYQ
|.|||.
ykfiyd

subfamily_PTPRB_pd Subfamily PTPRB 32-137 1.7e-20 68.3 In-house 177-279 (293) alignment
Range on Protein: 32-137
Range on HMM: 177-279/293.0
STREISHYQFTSWKEKTTPNVA-LFVGFVVASREVSKKyeQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEEskTSVVDLFEVAKRLRQARCGIISSLQ
..|.. .|.|||| .   |. .  .. || . ||. .|  .....|..|||| | | ||.|.|||  ... ||  . .||.| .  .||. |. .. . .
eerkvrqyhftsWpdhgvPektktlldfvrtvreaiek..taskrPivvhCsaGvGRtGtfialdrllqaiee..edyvdifgivaelReeRnllvqtek

HYNFIYQ
.| ||.|
qYifihq

subfamily_Nvec-PTP-2_pd Subfamily Nvec-PTP-2 32-137 3.9e-20 67.1 In-house 135-236 (250) alignment
Range on Protein: 32-137
Range on HMM: 135-236/250.0
STREISHYQFTSWKEKTTPNVALFVgfVVASREVSKKYEQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEESKtsVVDLFEVAKRLRQARCGIISSLQH
. | . ...|..| .|. |.||  |  .   ..| .. .| ..|||||.|| | | .| |.|.|  .   ...|  |||.|.| |.||. | . . ||. 
derivrqlhfvvWPdkgvPevatav..LellkkvqasqqqagnaPvivqCsaGvgrsGafiaidavlerlkkek..vvdvfkvikvlrkdrphavesleq

YNFIYQ
| |.|.
yvfvye

subfamily_Choan-PTP-1_pd Subfamily Choan-PTP-1 32-137 9.7e-20 65.8 In-house 168-270 (281) alignment
Range on Protein: 32-137
Range on HMM: 168-270/281.0
STREISHYQFTSWKEKTTPNVAlfVGFVVASREVSKKYEQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEeSKTSVVDLFEVAKRLRQARCGIISSLQH
 |||... ..|.| ..  |. .    ..   .|| |  |....||...||| | | ||...|||  |.. | .... .|. .| . ||..|  .. ..  
etreveqlaytaWPdhGvPatt..kellefrkevlkltekktkaplvihCsaGvGrtGtyialDrlvkave.aeleeldvkavvaelrkernlmvqtvvq

YNFIYQ
|.|.|.
yefvyk

subfamily_Urchin-PTPRA_pd Subfamily Urchin-PTPRA 32-136 4.1e-18 60.7 In-house 183-284 (319) alignment
Range on Protein: 32-136
Range on HMM: 183-284/319.0
STREISHYQFTSWKEKTTPNVALFVGFVVAS-REVSKKYEqeKDAPVIVHCSDGQGFTGVFVALDIGVRSHEESKtsVVDLFEVAKRLRQARCGIISSLQ
  |.|  . |  | ..  |. .  .  .|   | . .| .  . |...|||| | | |||...||. .   .| |   ||.... . ||| |  .. .| 
dirkitqfhflGwpdvGvpdypsdlmrlvkkvrhltsken..hranivvhcsaGvGrtGvyivldvlldrmkeek..qvdvynfvrdlrqqrntlvqdlv

HYNFIY
 | |||
qykfiy

subfamily_Sponge-PTP10_pd Subfamily Sponge-PTP10 32-137 4.6e-18 60.2 In-house 171-272 (287) alignment
Range on Protein: 32-137
Range on HMM: 171-272/287.0
STREISHYQFTSWKEKTtpNVALFVGFVVASREVSKKYEQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEesKTSVVDLFEVAKRLRQARCGIISSLQH
.....  ||.|.|...   .|. .   ..   |  |.  .. .....|||||. | ...|.| .....  .  .  |.|.|.| |. |. . | .   ..
dkqqvkqyqitnWdstg..kvtepqtillvieemyktqrkrgntsivvhCsdtvGrsamfcaaattinkck..teGviDvfqvlksqriqkpgsvqtveq

YNFIYQ
|.||..
ykfind

subfamily_Urchin-PTP-8_pd Subfamily Urchin-PTP-8 32-136 5.3e-18 60.5 In-house 147-248 (284) alignment
Range on Protein: 32-136
Range on HMM: 147-248/284.0
STREISHYQFTSWKEKTTPNVALFVGFVVAS-REVSKKYEqeKDAPVIVHCSDGQGFTGVFVALDIGVRSHEESktSVVDLFEVAKRLRQARCGIISSLQ
  |.|  . |  | ..  |. .  .  .|   | ...| .  . |...|||| | | |||...||. .   .|   . ||.... . ||| |  .. .| 
dirkirqfhflgwpdvgvpdypsdlmrlvkkvrhltsken..hranivvhcsagvgrtgvyivldvlldrmkee..kqvdvynfvrdlrqqrntlvqdlv

HYNFIY
 | |||
qykfiy

subfamily_PTPN12_pd Subfamily PTPN12 32-137 3.8e-17 57.1 In-house 168-271 (290) alignment
Range on Protein: 32-137
Range on HMM: 168-271/290.0
STREISHYQFTSWKEKTTPNVALFvgfVVASREVSKKYEQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEESKT-SVVDLFEVAKRLRQARCGIISSLQ
 .|..  ...|.| .. .|. |     ...  |  .......|||..|||| | | ||. .|.|.  .  .. |. . .|.|..  .||. |  .. . .
esrkvyqfhYtaWPDhgvPssaks...llelielvrelqesedaPlvvhCsaGvGrtGtiiaidyvrellkaekipeeldvfdlvlelrkqraalvqtke

HYNFIYQ
 |...|.
qyelvyk

subfamily_Sponge-PTP9_pd Subfamily Sponge-PTP9 32-137 6.7e-17 56.1 In-house 186-287 (301) alignment
Range on Protein: 32-137
Range on HMM: 186-287/301.0
STREISHYQFTSWKEKTT---PNVALFVgfvVasREVSKKYEQEKDAPVIVHCSDGQGFTGVFVALDIGVrshEESK-TSVVDLFEVAKRLRQARCGIIS
|....  .| |.| .      |.  | |   .   .| ..  .   .||.|||||. . .||.....||.   |  |   |||.|.| |..|. . | . 
sswdvlqlqvtdWpqdGvvreprtvLqv...i..ddvihrqqkigggpvvVHCSdtVsrsGvYcsvsigl...EQckaegVVdvfqvtkavrrskpgaVt

SLQHYNFIYQ
 |. | .||.
TLeqytsiyd

subfamily_Anemone-PTP-4_pd Subfamily Anemone-PTP-4 32-137 2.4e-15 51.4 In-house 131-233 (237) alignment
Range on Protein: 32-137
Range on HMM: 131-233/237.0
STREISHYQFTSWKEKTTPNVALFVgFVVASREVSKKYEQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEESKtsVVDLFEVAKRLRQARCGIISSLQH
  | |  |||||| ..  |. .  . .    . . .     . .| |.||| | | ||.|. .|  .|  .| |  |||...  . . . |  || . ..
evrlihqyqftswpdrgvpqqtaal.lrfrkniinrsphvsesgpwiihcsagvgrtgiflvidamlrqakekk..vvdiynyvysieedrpyiiqtkdq

YNFIYQ
| ||.|
yvfihq

subfamily_Sponge-PTP6_pd Subfamily Sponge-PTP6 32-136 6.3e-14 46.3 In-house 172-272 (439) alignment
Range on Protein: 32-136
Range on HMM: 172-272/439.0
STREISHYQFTSWKEKTTPNVALFVGFVVasREVSKKYEQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEesKTSVVDLFEVAKRLRQARCGIISSLQH
  | . ......| .|  |  | .|   .  | .    ..|.  ||.|||| | | ||  .|||| .          ||.  . | ||. |  .. .| .
kertvlqfhyiawpdknvpaqashvldfl..rainsandkeeygpvvvhcsagvGrtGtiialdialeqlk..lenkvdikgivkvlrkqrkqmvqalcq

YNFIY
| |||
yvfiy

subfamily_Sponge-PTP1_pd Subfamily Sponge-PTP1 32-136 7.2e-11 36.6 In-house 154-252 (267) alignment
Range on Protein: 32-136
Range on HMM: 154-252/267.0
STREISHYQFTSWKEKTTPNVALFVGFVVasreVSKKYEQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEesKTSVVDLFEVAKRLRQARCGIISSLQH
|..... | .  |. .|  .  |   | .    ..|.  .. . |..|.|||| | .| |. .|  ..     . .|.|.|.  ...|. | |.. ....
sahnvtlyyykkwnintnnkpylkplfgi....laknqlengnrPlvvacsdGvGrsGtflvidsqlerak..tegvsdifdflrkirsqriglvdtker

YNFIY
| .|.
yiyih

subfamily_Cele-PTP-19_pd Subfamily Cele-PTP-19 32-132 3.4e-10 34.1 In-house 179-271 (301) alignment
Range on Protein: 32-132
Range on HMM: 179-271/301.0
STREISHYQFTSWKEKTTPNVALFVgfvVASREVSKKYEQekdaPVIVHCSDGQGFTGVFVALDIGVRSHEESKTsvVDLFEVAKRLRQAR-CGIISSLQ
.|| . |||...| .. .|.    .       |. || |.    |..||||.| | .  |.. ..  |  |  .|  ..| |  |.||. | .|.    |
atrtvthyqysewtdrgvPkshael...fdlmelvkksek....PivvhcsaGiGrsvafigteylareveadpt..ieltealkhlrehrwngvqtnsq

HY
 |
ly

subfamily_Cele-PTP-9_pd Subfamily Cele-PTP-9 32-127 1.7e-09 32.1 In-house 114-205 (255) alignment
Range on Protein: 32-127
Range on HMM: 114-205/255.0
STREISHYQFTSWKEKTTPNVALFVGFVVASREVSKkyeqekdaPVIVHCSDGQGFTGVFVALDIG----VRSHEESKTSVVDLFEVAKRLRQARCGIIS
 |... ||... | || .|. |  . ...     ||        .|.|||| | | .  ||  ..     .|| ....|  .|  .. . ||. | . | 
kthtvkhysykGWieknaPelareilnilkvvrdsk........svvvhCstGiGrsaafvlaelvyqkmirsldttetveldylslleelrskrkraih





subfamily_Cele-PTP-6_pd Subfamily Cele-PTP-6 32-135 1.8e-09 32.0 In-house 174-269 (307) alignment
Range on Protein: 32-135
Range on HMM: 174-269/307.0
STREISHYQFTSWKEKTTPNVALFVGFVVASrevsKKYEQekdAPVIVHCSDGQGFTGVFVALDIgVRSHEESKTSVVDLFEVAKRLRQARCGIISSLQH
 .| |.|.|.. | .. .|.. |    .. .     .|..    ||.|||| | | .|  ||. . |.    .     |. .. . ||. |   | .   
ksrtiqhlqwenwpdrgvpqinltainllea....vrydt...npvvvhcsaGvGrsGtivaisl.vqdkmiaGinckdmkklveelrsqrhyaiqteaq

YNFI
| ..
ylyl

subfamily_ptpA1_pd Subfamily ptpA1 32-96 6.9e-07 23.3 In-house 184-251 (418) alignment
Range on Protein: 32-96
Range on HMM: 184-251/418.0
STREISHYQFTSWKEKTTPNVALFVG---FVVASREVSKKYEQEKDAPVIVHCSDGQGFTGVFVALDI
 ||.|..||.  | ..  |. .  .    . .. |.       ... |.||||| | | || |..  |
etrditqyqyegwpdhnipdhtqpfrqllhsitnrqnqiipssdrnvpiivhcsagvgrtgtfctavi

subfamily_hpo-7_pd Subfamily hpo-7 32-127 1.9e-06 22.0 In-house 120-211 (263) alignment
Range on Protein: 32-127
Range on HMM: 120-211/263.0
STREISHYQFTSWKEKTTPNVALFVGFVVASREVSKkyeqekdaPVIVHCSDGQGFTGVFVALDIG----VRSHEESKTSVVDLFEVAKRLRQARCGIIS
 |... ||... | ||  |. |  .  ..     ||        ...|||| | | .  |.  ..     .|| ....|  .|  .. . ||. | . | 
kthtvkhysykgWiekndpelareilnilkvarnsk........slvvhcstGiGrsaafsvaElvyqkmirsldttstveldylsLleelrssrkraih





subfamily_PTPN5_RR_pd Subfamily PTPN5_RR 33-137 2.5e-22 74.3 In-house 160-262 (274) alignment
Range on Protein: 33-137
Range on HMM: 160-262/274.0
TREISHYQFTSWKEKTTPNVALFVGFVVASREVSKKYEQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEEskTSVVDLFEVAKRLRQARCGIISSLQHY
.|.. || .|.| .. .|. |  .  .|.  | |.. |..| |||.|||| | | ||.|.| .|.||  .|  ..|||....   ||. | |.. . . |
ersvkhywytdWPdhksPddantlldlvleveesreeenaklapvvvhCsaGiGrtGcfiaisiavrqlre..eivvdvlkivcnlrldrGGmvqtseqy

NFIYQ
..|..
elihr

subfamily_Urchin-PTPRB-like_pd Subfamily Urchin-PTPRB-like 33-137 1.4e-20 68.6 In-house 174-273 (288) alignment
Range on Protein: 33-137
Range on HMM: 174-273/288.0
TREISHYQFTSWKEKTTPNVAL-FVGFVvasREVsKKYEQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEEskTSVVDLFEVAKRLRQARCGIISSLQH
 .|| .||...| ..  |. .  .....   | | |  .|..  |.|||||.| | ||.|.|||  .   ||  . ..|.... ..||. |  ..  |..
eleitqyqylaWpdhgvPeskapllell...rqv.kvanqadtgpiivhCsaGvGrtgtFialdalidavee..edyiDvagtvaklRkqRallvqtlkq

YNFIYQ
| |||.
Yefiye

subfamily_Urchin-PTP-7_pd Subfamily Urchin-PTP-7 33-137 4.6e-19 63.5 In-house 174-273 (315) alignment
Range on Protein: 33-137
Range on HMM: 174-273/315.0
TREISHYQFTSWKEKTTPNVAlfVGFVVASREVsKKYEQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEESKtsVVDLFEVAKRLRQARCGIISSLQHY
 ||.  ...||| .   |. .  . ..   | | |...... ....||||.|.| || |..||  .   |  .  ..|.... ...|| | ....... |
irevvqlhytswpdmgvpkyt..iplmnlirtv.kqhhtnsvgaivvhcsaGvGrtGtfitldavldqaeaen..aidvynfitgvrqnrikmvqvaeqy

NFIYQ
.|||.
qfiyd

subfamily_PTPN14_pd Subfamily PTPN14 33-137 5.2e-19 63.4 In-house 182-290 (300) alignment
Range on Protein: 33-137
Range on HMM: 182-290/300.0
TREISHYQFTSWKEKTTPN-VALFVGFVVASREVSKKYEQEK-----DAPVIVHCSDGQGFTGVFVALDIGVRSHEESKtsVVDLFEVAKRLRQARCGII
 |.. | |.| | ..  |. |  |. ..   . | .| ..|.     . ||.||||.| | ||| .  |. . . |  .  ..|. .| .|||. |  ..
ertvwhlqytDWpdhgvPeDvkgflsyLeevqsvrrktnseveskeskPPvlvhCsaGvGrtGvlilsdlliatlehne..eidikkvlarLreqrmllv

SSLQHYNFIYQ
..|  |.|.|.
qtlaqYkfvYk

subfamily_Sponge-PTP5_pd Subfamily Sponge-PTP5 33-136 2.3e-17 57.8 In-house 161-259 (283) alignment
Range on Protein: 33-136
Range on HMM: 161-259/283.0
TREISHYQFTSWkekTTPNVALFVGFVVASREVSKKYEQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHeeSKTSVVDLFEVAKRLRQARCGIISSLQHY
|  ..|||.  |   .  .    .  .|    |  .  ..|..|..|||| | | |.||.|.   |        ||||.|.| | .|. | ... .|. |
tlllahyqvidW...leygeqaiinslvkfnkvislqteskkgPivvhCstgiGrtavfiaasasvkda..ltesvvdvfavvkimreqrmmavqtldqy

NFIY
 ...
klvh

subfamily_Urchin-PTP-1_pd Subfamily Urchin-PTP-1 33-137 4.1e-17 57.0 In-house 172-271 (315) alignment
Range on Protein: 33-137
Range on HMM: 172-271/315.0
TREISHYQFTSWKEKTTPNVALfvGFVVASREVSKKyEQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHeeSKTSVVDLFEVAKRLRQARCGIISSLQHY
.| .. .||| | .| ... .    ..   .||  . ...|. ...|||| | | |||....|  |      .|..||.|.. | ||. |  .. . ..|
srtvtqfqftewPdkGvdkqts..sllklikevkad.ngkkefsllvhcsaGvGrtGvvisidevvaqi..krtrsvdvfnfvknlrakrpylvqteeey

NFIYQ
 |||.
afiyd

subfamily_Urchin-PTP-6_pd Subfamily Urchin-PTP-6 33-137 2.7e-16 53.8 In-house 171-270 (515) alignment
Range on Protein: 33-137
Range on HMM: 171-270/515.0
TREISHYQFTSWKEKTTPNVAlfVGFVVASREVSKKYEQEKdAPVIVHCSDGQGFTGVFVALDIGVRSHeeSKTSVVDLFEVAKRLRQARCGIISSLQHY
.| .  ..|| | .| .|. .    ..   .||  . .| .  |.|.||| | | |||....|  |      .| .||.|.. . .|| |  ..   ..|
srtvtqfhfteWPdkGvpkht..ssllklikevkadhgqyt.hpliihcsaGvGrtGvvisidsvvaha..kttrmvdvfnfvtnirqkrpylvqtqeqy

NFIYQ
 |||.
afiyg

subfamily_Urchin-PTP-2_pd Subfamily Urchin-PTP-2 33-136 2.8e-12 40.7 In-house 88-187 (440) alignment
Range on Protein: 33-136
Range on HMM: 88-187/440.0
TREISHYQFTSWKEKTTPNVALFVGFVVasREVSKKYEQEKDAPVIVHCSDGQGFTGVFVALDIGVRshEESKTSVVDLFEVAKRLRQARCGIISSLQHY
.| . .|.. .| .|  |..|  |  ..  ..|..  |.  ..|..|||| | | ||| .|.|  .|  |  ..  .|.| . . .|. |  .. . ..|
srtlkqyhyqgwpdkgvpkfagpvlkmi..qdvnesqekagngpllvhcsagagrtgviiavdsilr..eakrsdqidifsfinsmrnnrpqmvqtpeqy

NFIY
 |..
afvh

subfamily_Cele-PTP-13_pd Subfamily Cele-PTP-13 33-136 2.9e-07 24.4 In-house 166-262 (281) alignment
Range on Protein: 33-136
Range on HMM: 166-262/281.0
TREISHYQFTSWKEKTTPNVALFVGfvvasrEVSKKYEqEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEeSKTSVVDLFEVAKRLRQ-ARCGIISSLQH
|| |.|. .  | .   |. .  .       .. .|    . .| ..||| | | .| ..|..| ..|   |. .. |. ..  .||   |.  . .||.
trlithwlwkewpdwqvpessevml......kilrkir.arstppvihcsagvgrsgtlmaveialqsih.shftlpdikqivshlrvtgraasvqtlqq

YNFIY
| .|.
ymliw

subfamily_Anemone-PTP-1_pd Subfamily Anemone-PTP-1 34-136 4.8e-13 43.8 In-house 137-234 (239) alignment
Range on Protein: 34-136
Range on HMM: 137-234/239.0
REISHYQFTSWKEKTTPNVALFVgfVVASREVSKkYEQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEESKTsvVDLFEVAKRLRQARCGIISSLQHYN
| . .|.|| | .|  |. |  |  .   |...|        | ..||| | | || |. .|  .|  .. ||  ||.|.  | .|. |  .. . ..| 
ryvyqyhftvwpdkgvpqyatav..lglrrkitk.dslpgarpwvihcsagvgrtgaflvidamlrqakkqkt..vdifnyvkairedrphmvqtseqyv

FIY
||.
fih

subfamily_Nvec-PTP-1_pd Subfamily Nvec-PTP-1 34-136 4.8e-13 43.8 In-house 136-233 (239) alignment
Range on Protein: 34-136
Range on HMM: 136-233/239.0
REISHYQFTSWKEKTTPNVALFVgfVVASREVSKkYEQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEESKTsvVDLFEVAKRLRQARCGIISSLQHYN
| . .|.|| | .|  |. |  |  .   |...|        | ..||| | | || |. .|  .|  .. ||  ||.|.  | .|. |  .. . ..| 
ryvyqyhftvwpdkgvpqyatav..lglrrkitk.dslpgarpwvihcsagvgrtgaflvidamlrqakkqkt..vdifnyvkairedrphmvqtseqyv

FIY
||.
fih

subfamily_Cele-PTP-20_pd Subfamily Cele-PTP-20 34-127 1.2e-10 35.6 In-house 183-267 (290) alignment
Range on Protein: 34-127
Range on HMM: 183-267/290.0
REISHYQFTSWKEKTTPNVALFVGFVVasREVskkyeQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEESKTsvVDLFEVAKRLRQARCGIIS
  . |..  || .|. .. .| .  ..  | .     ..   ||.|||| | | || |||...|..   . |   .|| .. . ||..| . . 
hklkhlkikswpdksvalstlallrtl..ril.....rkasGpvvvhcsaGiGrtGtfvaievglqilldGke..ldlldlvralrnsrlnsvq

subfamily_Choan-PTP-3_pd Subfamily Choan-PTP-3 34-136 1.4e-10 35.4 In-house 168-270 (287) alignment
Range on Protein: 34-136
Range on HMM: 168-270/287.0
REISHYQFTSWKEKTTPNV-ALFVGFVVAS-REVSKKYEQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEEskTSVVDLFEVAKRLRQARCGIISSLQH
| .  ... || .|. .     .. ||.   . .  . . ..  |..||.. | | .|...|. . |.  |.  .  ||   |  |||. | ... .   
rvvkqldllswPdkvlaPtavglirfvldvkqhielardasevGPlvvhddvGiGrsGillatlvlvsrled..lGrvdvaavvirlreyraalvqavvq

YNFIY
. ..|
lrlly

subfamily_Cele-PTP-10_pd Subfamily Cele-PTP-10 34-136 6.9e-08 26.5 In-house 188-282 (305) alignment
Range on Protein: 34-136
Range on HMM: 188-282/305.0
REISHYQFTSWKEKTTPNVALfvgfvvASREVSKKYEQEKdAPVIVHCSDGQGFTGVFVALDIGVRSHEESKTsVVDLFEVAKRLRQARCGIISSLQHYN
  . | |.| | ..  | . |      .| |.       |  |..|||| | | ||  ||..  .    | |  .  . |. | ||. |.  | .  .| 
msvrhlqwtewpdrgvppckl......tslellsairgsk.vpivvhcsagigrtgtivaieyilekiaenkp.cppmpelvkalrdqrafsiqndvqyl

FIY
||.
fih

subfamily_Cele-PTP-1_pd Subfamily Cele-PTP-1 35-135 2.8e-10 34.8 In-house 159-251 (290) alignment
Range on Protein: 35-135
Range on HMM: 159-251/290.0
EISHYQFTSWKEKTTPNVALFVGFVVasrevsKKYEqEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEESKTSVvDLFEVAKRLRQARCGIISSLQHYNF
 . |... .|..  ...  . .  ..      .| .  ...|||||| ||     .. |...|     |.. ||  | .| | ||. |   |.| . . |
tvtHsllkgWnklnvqedtktllsli......qkvk.asktpvivHcvdGiSrsAalaaiilgyQkiaetsgsv.kledvlkalrkqralaitsalelaf

I
.
v

subfamily_Cele-PTP-11_pd Subfamily Cele-PTP-11 35-119 2.9e-07 24.5 In-house 177-255 (312) alignment
Range on Protein: 35-119
Range on HMM: 177-255/312.0
EISHYQFTSWKEKTTPNVAlfvgfVVASREVSKKYEQEKdaPVIVHCSDGQGFTGVFVALDIGVRSH-EESKTSVVDLFEVAKRLR
 . |||..|| ..  |.         | | .|    . |  ||| ||| | | || .. ..  . .     |  | | | . .. |
klnhyqwaswpdhgmpdsc.....dtalrllsavkkdkk..pviahcsagvgrtgtlaliesmiaalrhprkqnvkdsfvllrkdr

PTPc_DSPc_SM00012 36-137 3.7e-23 77.1 In-house 2-101 (105) alignment
Range on Protein: 36-137
Range on HMM: 2-101/105.0
ISHYQFTSWKEKTTPNVAlfVGFVVASREVSKKYEQEK-DAPVIVHCSDGQGFTGVFVALDIGVRSHEESKtSVVDLFEVAKRLRQARCGIISSLQHYNF
..||..|.|... .|. .    .. . |.| |......  .||.||||.| | ||.|||||| ....|... . ||.|.. |.||. | | ..... | |
vkhyhytgwpdhgvPees..dsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleket.kevdifqivkelrkqRpgmvqteeqylf

IYQ
.|.
lyr

subfamily_PTEN_pd Subfamily PTEN 36-132 1.9e-06 23.0 In-house 82-171 (184) alignment
Range on Protein: 36-132
Range on HMM: 82-171/184.0
ISHYQFTswkEKTTPNVALFVGFVvasREVSKKYEQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEESKTSVVDLFEvAKRLRQARCGIISSLQHY
...|.|.   ....|.. |.  .|   ....|  |..|.  |.|||  |.| ||| ..  .  . . |.......||. ..| .....  | | . |
vavypfd...Dhnppplelleeiv...ediekwleedkknvvvvHCkaGkGRtGvlivayllkslllekaeealelfa.eaRtknkkgvtiPsqrRY

subfamily_Cele-PTP-4_pd Subfamily Cele-PTP-4 39-136 1.9e-08 28.1 In-house 186-278 (302) alignment
Range on Protein: 39-136
Range on HMM: 186-278/302.0
YQFTSWKEKTTPnvALFVGFVVASREVsKKYEQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEESktSVVDLFEVAKRLRQARCGIISSLQHYNFIY
| .| ||.|. |    .   . .  .|  . ... |.....    | |  |.|..| . | . ...  . .   |..| .|. |. .. ||. |...|
yvltnWkqkkvp..vkyaeliktaakv.fakkikadentvivSknGaGRagafltlavaveklqkg..kepnikeivksiRsqRpravdslkQyvsly

subfamily_Fungi-PTP1_pd Subfamily Fungi-PTP1 63-136 1.3e-08 29.0 In-house 250-337 (350) alignment
Range on Protein: 63-136
Range on HMM: 250-337/350.0
REVS-KKYEQEKDAPVIVHCSDGQGFTGVFVALDIGVRS------------HEESKTSVVDLFE-VAKRLRQARCGIISSLQHYNFIY
  .. . ..... .|..|||| | | ||..|.||  .              . .  . . || . . ..||. |  .. .|. . |||
dlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaaktrDlisiivnelrkqrismvqnldqfifiY

subfamily_CG42327_pd Subfamily CG42327 65-137 8e-17 55.9 In-house 238-309 (319) alignment
Range on Protein: 65-137
Range on HMM: 238-309/319.0
VSKKYEQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEESKTSvVDLFEVAKRLRQARCGIISSLQHYNFIYQ
 |.  ..|.  |..|||||| | ||. .| || .|| |||| | ||. ..   .|. |.  . . . |.|||.
ssrsgtresqGPlvvhcsdGvGrtGlviasdiairsleeskrs.vdiPqlvssvrrdrasavltkeqyefiyk

subfamily_Choan-PTP-4_pd Subfamily Choan-PTP-4 66-137 1.7e-08 28.7 In-house 220-289 (297) alignment
Range on Protein: 66-137
Range on HMM: 220-289/297.0
SKKYEQEKDAPVIVHCSDGQGFTGVFVALDIGVrsHEESKTSVVDLFEVAKRLRQARCGIISSLQHYNFIYQ
| . |. ..|...|||| | | .|| |  |. .      |  . |   . . ||. |  .. .|. ....|.
slraemprnayllvhcsaGvGrsGvvvlsdvil..aklrkkripdvaailsilreqrarlvqtleqfellyd

subfamily_Fungi-PTP2_pd Subfamily Fungi-PTP2 66-110 4.1e-07 23.6 In-house 257-301 (349) alignment
Range on Protein: 66-110
Range on HMM: 257-301/349.0
SKKYEQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEESKTSVVD
 . ..... ....|||| | | |||.| ||. .   |  .   . 
rlyldtdqlstllvhcsaGcGrtGvlvtldlllsileplqnesnk

subfamily_Sponge-PTP-7_pd Subfamily Sponge-PTP-7 78-136 9.2e-07 23.2 In-house 2-58 (69) alignment
Range on Protein: 78-136
Range on HMM: 2-58/69.0
IVHCSDGQGFTGVFVALDIGVRSHEESKtsVVDLFEVAKRLRQARCGIISSLQHYNFIY
.|||| | | || |.|. . .      |  .||.|.  . .|. |  ..   . | ||.
vvhcssgtgrtgtfiaimvemariksek..lvdifnnvqymrkcrpmmvmneieyifih

subfamily_Sponge-PTP7_pd Subfamily Sponge-PTP7 78-136 1.6e-06 22.4 In-house 1-57 (69) alignment
Range on Protein: 78-136
Range on HMM: 1-57/69.0
IVHCSDGQGFTGVFVALDIGVRSHEESKtsVVDLFEVAKRLRQARCGIISSLQHYNFIY
.|||| | | || |.|. . .      |  .||.|.  . .|. |  ..     | ||.
vvhcssGtGrtGtfiaimvemariksek..lvdifnnvqymrkcrpmmvmneneymfih