Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
---|---|---|---|---|---|---|---|---|---|
0043147 | (Phosphotyrosine protein) phosphatases II | 1-137 | 3.6e-24 | 80.8 | In-house | 33-155 (172) | alignment | ||
Range on Protein: 1-137
Range on HMM: 33-155/172.0
MADFWQMVWETGSGHIVMVNDDqknKETAPPSTREISHYQFTSWKEKTTPNVALFVGFVvasREVSKKYEQEKDAPVIVHCSDGQGFTGVFVALDIGVrs
.||||.|..| | .|||.... .... .|.. .|....| ..|. .|. |. . . ... .... ||.|||| | | ||..||...
ladfwrmlkelgithivnltel...lydpellerlgiqylylpwpDhgvpllelllefl...efidellalspggpvlVHCsaGvgRtgtlvaaylml..
heesktS-VvDLFEVAKRLRQARCGIISSLQHYNFIYQ
. .|.|. . .|..|.|.. . ..|.|.|.
......lgl.sleeavalvrekRpgavqnpsqyrflyy
|
|||||||||
0049260 | (Phosphotyrosine protein) phosphatases II | 1-137 | 4e-22 | 74.0 | In-house | 22-144 (152) | alignment | ||
Range on Protein: 1-137
Range on HMM: 22-144/152.0
MADFWQMVWETGSGHIVMVNDDQKNKETAPPSTReisHYQFTSWKEKTTPNVALFVGFVVASREVSkkyEQEKDAPVIVHCSDGQGFTGVFVALDIGVrs
.||||.|..| | ..|||..... ... . .|... | ..|. . .. |.. | ..|. ||.|||| | | ||..||...
ladfwrmlkelgittivmltellelgklkceqyi...qylhlpwpDhgvpdlsqlllflllfiekl...aldkggpvlVHCsaGvgRtgtlvaaylml..
heesktSVVDLFEVAKRLRQARCGIISSLQHYNFIYQ
|.|.|. ...|..| |.. . ... |.|.
......lgvsleeavalvrekRpgavpnpgqlrflye
|
|||||||||
subfamily_Urchin-PTP-4_pd | Subfamily Urchin-PTP-4 | 1-136 | 2.2e-21 | 70.7 | In-house | 101-229 (392) | alignment | ||
Range on Protein: 1-136
Range on HMM: 101-229/392.0
MADFWQMVWETGSGHIVMVNDDQKNKETapPSTREISHYQFTSWKEKTTPNVALfvGFVVASREVSKKYEQEKdAPVIVHCSDGQGFTGVFVALDIGVrS
. |||.||.. |.||.. .. ..| .. ..|| | .| |. . .. .||. .. | |.|.||| | | ||| ...| | .
lddfwrmvfqenvttiamvtklkegdkg..ddartvaqfhftewPdkdvpkhts..sllkfikevkadfGqyt.hpliihcsagvgrtgvvisidsvv.a
HEeSKTSVVDLFEVAKRLRQARCGIISSLQHYNFIY
| || .||.|.. .|. | .. . ..| |||
ha.kktrmvdvfnfvtnirrkrpymvqtkeqyafiy
|
|||||||||
0051082 | (Phosphotyrosine protein) phosphatases II | 1-137 | 7.5e-21 | 69.7 | In-house | 22-147 (151) | alignment | ||
Range on Protein: 1-137
Range on HMM: 22-147/151.0
MADFWQMVWETGSGHIVMVNDDQ---KNKETAPPSTREISHYQFTSWKEKTTPNV----ALFVGFVVAsrevskkyeqEKDAPVIVHCSDGQGFTGVFVA
.|||.....| | .||...... ...| | .|. |.....|.. ..| . |. .. . |. ||.|||| | | ||..||
ladflellkelgiktivnlrseeergycpeylpelgievlhipildwpdpglplsfdavleflellld..........kkngpvlvHCsaGkgRTGtlva
LDIGVRSheesktsvVDLFEVAKRLRQARCGIISSLQHYNFIYQ
|.. . |.|.|. . .|. |.|.. . |.. |...
lylmllg........vsleealeeyrlkrpgvvqpnqqflfqlf
|
|||||||||
0046846 | (Phosphotyrosine protein) phosphatases II | 1-137 | 7.9e-21 | 70.0 | In-house | 36-167 (176) | alignment | ||
Range on Protein: 1-137
Range on HMM: 36-167/176.0
MADFWQMVWETGSGHIVMVNDDQKNKET-----APPSTREISHYQFTSWKEKTTPNVALFVGFVVASREVSKKYeqekdAPVIVHCSDGQGFTGVFVALD
.|||..|..| | ...|...... . | ... .|... | . ..|. .|. .. . ||. |. ||.|||| | | ||..||..
ladflemlkelgitavvnlteevelgrlkcpnywpeleklgiqylhlpwpDhgvpdlelllellefirealkeg.....gpvlVHCsaGigRtgtlvaay
IGVRsheeskTSVVDLFEVAKRLRQARC-GIISSLQHYNFIYQ
. . ....|. ...|. |. |.. . ..| |.|.
llel......ekglsveealalvreqRplgavqtpeQyrflye
|
|||||||||
subfamily_Anemone-PTP-3_pd | Subfamily Anemone-PTP-3 | 1-28 | 9.2e-17 | 55.9 | In-house | 18-45 (199) | alignment | ||
Range on Protein: 1-28
Range on HMM: 18-45/199.0
MADFWQMVWETGSGHIVMVNDDQKNKET
|||||||||||||||||||||||||||.
madfwqmvwetgsghivmvnddqknkea
|
|||||||||
subfamily_Nvec-PTP-3_pd | Subfamily Nvec-PTP-3 | 1-28 | 1.2e-16 | 55.4 | In-house | 17-44 (198) | alignment | ||
Range on Protein: 1-28
Range on HMM: 17-44/198.0
MADFWQMVWETGSGHIVMVNDDQKNKET
.||||||||||||||||||||||||||.
ladfwqmvwetgsghivmvnddqknkea
|
|||||||||
DSPc_SM00195 | 1-27 | 2.1e-06 | 22.7 | In-house | 82-108 (263) | alignment | |||
Range on Protein: 1-27
Range on HMM: 82-108/263.0
MADFWQMVWETGSGHIVMVNDDQKNKE
..|||.||||... |||......|..
vedFWrmvweekvkiivmlteeeengk
|
|||||||||
PTPc_SM00194 | 1-27 | 2.1e-06 | 22.7 | In-house | 82-108 (263) | alignment | |||
Range on Protein: 1-27
Range on HMM: 82-108/263.0
MADFWQMVWETGSGHIVMVNDDQKNKE
..|||.||||... |||......|..
vedFWrmvweekvkiivmlteeeengk
|
|||||||||
subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 1-27 | 2.2e-06 | 22.0 | In-house | 105-131 (297) | alignment | ||
Range on Protein: 1-27
Range on HMM: 105-131/297.0
MADFWQMVWETGSGHIVMVNDDQKNKE
.||||.||.. |||.|||.....
vadfWamvldeqvstivmlnddnerdk
|
|||||||||
subfamily_PTPRD_pd | Subfamily PTPRD | 1-26 | 2.8e-06 | 21.2 | In-house | 104-129 (564) | alignment | ||
Range on Protein: 1-26
Range on HMM: 104-129/564.0
MADFWQMVWETGSGHIVMVNDDQKNK
..|||.|||| | |||.. . ..
iedFWRmvweqnsstiVmltkleEkg
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 1-26 | 3.8e-06 | 21.9 | Pfam-A | 55-80 (235) | alignment | ||
Range on Protein: 1-26
Range on HMM: 55-80/235.0
MADFWQMVWETGSGHIVMVNDDQKNK
..|||.|||. . |||........
iedFWrmvwqekvkvivmltsleekg
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 1-26 | 3.8e-06 | 21.9 | In-house | 55-80 (235) | alignment | ||
Range on Protein: 1-26
Range on HMM: 55-80/235.0
MADFWQMVWETGSGHIVMVNDDQKNK
..|||.|||. . |||........
iedFWrmvwqekvkvivmltsleekg
|
|||||||||
0046845 | (Phosphotyrosine protein) phosphatases II | 2-137 | 1.6e-34 | 115.0 | In-house | 91-268 (284) | alignment | ||
Range on Protein: 2-137
Range on HMM: 91-268/284.0
ADFWQMVWETGSGHIVMVNDDQKNKETA------------------------------------------PPSTREISHYQFTSWKEKTTP-NVALFVGF
.|||.|||| .. .|||... |. . . .|.. |...||| . .| ... .. |
edFwrmvweqnvrvIVmltelvengrekcaqYwplegevltygdftvtllseevkddytvrtleltnlgytgesrtvthfhytswpdhgvppspedllef
VVASREVSKKyeQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEESK-TSVVDLFEVAKRLRQARCGIISSLQHYNFIYQ
. . ||. .. ... |..||||.| | ||.|.|||. . |. . ...||..|. ||||. |.| . .|..| |.|.
lrlvrellen..lpgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvqtleqyrfvye
|
|||||||||
0051299 | (Phosphotyrosine protein) phosphatases II | 2-137 | 6e-34 | 113.2 | In-house | 106-280 (288) | alignment | ||
Range on Protein: 2-137
Range on HMM: 106-280/288.0
ADFWQMVWETGSGHIVMVNDDQKNKE--------------------------------------------TAPPSTREISHYQFTSWKEKTTPN-VALFV
.|||.|||| .. .|||... . .. . . .|.. |...|.| . .|. . |..
edFWrmvweqnvrvIvmltklvelgrekcaqYwplggsltygditvtllseevlddytvrtlevtnldlldgdgesrtvthfhytnwpdhgvpdspelll
GFVVASREVSKkyeqEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEESktSVVDLFEVAKRLRQARCGIISSLQHYNFIYQ
|. . |.. . .. ||.||||.| | ||.|.|||. .. |. .||..|. ||||. |.|.. ....| |.|.
dflrlvrkala....sgggpvvVHCsaGvgRtgtfialdllleqleke..ggvdvleavkrlreqRpgmvqtpeqyrfvye
|
|||||||||
0050432 | (Phosphotyrosine protein) phosphatases II | 2-137 | 6.1e-34 | 113.1 | In-house | 122-293 (308) | alignment | ||
Range on Protein: 2-137
Range on HMM: 122-293/308.0
ADFWQMVWETGSGHIVMVNDDQKNKE-------------------------------------------TAPPSTREISHYQFTSWKEKTTPN-VALFVG
.|||.|||| .. .|||... . |. . . .|.. |...|.|.. .|. .. ..
edFwrmvweqnvrvIvmLtklvengrekcaqYwplelgggsleygkftvtllseevlddytvrtleltnlgdgesrtvthfhytnWpdhgvPpspeilld
FVVASREVSkkyeqeKDAPVIVHCSDGQGFTGVFVALDIGVRSHEESktSVVDLFEVAKRLRQARCGIISSLQHYNFIYQ
|. . |.. .. |..||||.| | ||.|.|||. .. |. ||.||. |.||. |.| . ....| |.|.
flelvrksl......pggpivVHCsaGvGRtGtfialdllleqleke..ggvdvfeavkklReqRpgmvqtpeqylflyr
|
|||||||||
0036941 | (Phosphotyrosine protein) phosphatases II | 2-137 | 3.8e-33 | 110.5 | In-house | 92-271 (297) | alignment | ||
Range on Protein: 2-137
Range on HMM: 92-271/297.0
ADFWQMVWETGSGHIVMVNDDQKNKE--------------------------------------------TAPPSTREISHYQFTSWKEKTTPN-VALFV
.|||.|||| .. .|||.... . | . .|.. |...|.| . .|. .| ..
edFWrmvweqnvtvIvmltelvelgrekcaqywpleegesltygdftvtllsvevvllddytlrtlevtdtgngesrtvthfhytgwpdhgvpespasll
GFVVASREVSKKYeqEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEES-KTSVVDLFEVAKRLRQARCGIISSLQHYNFIYQ
|. . |.| |.. .. ||.||||.| | .|.|.|.|. .. |.. |. ||..|. | ||. |.|.. .|..| |.|.
dfielvrkvlkll..psggpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflye
|
|||||||||
0047943 | (Phosphotyrosine protein) phosphatases II | 2-137 | 4.4e-33 | 110.3 | In-house | 91-266 (273) | alignment | ||
Range on Protein: 2-137
Range on HMM: 91-266/273.0
ADFWQMVWETGSGHIVMVNDDQKNKET-------------------------------------------APPSTREISHYQFTSWKEKTTP-NVALFVG
.|||.|||| .. .|||..... .. . .|.. |...|.| . .| ... ..
edfwrmvweqnvrviVmLtelvelgrekcaqYwpleggelsltygkftvtllseetkddytvrtleltnlgtgesrtvthfhytgwpdhgvppsleslle
FVVASREVSKKYEQEkdAPVIVHCSDGQGFTGVFVALDIGVRSHEESktSVVDLFEVAKRLRQARCGIISSLQHYNFIYQ
|. . |.. ... .. ||.||||.| | ||.|.|||. .. |. ||..|. |.||. |.|.. ....| |.|.
fielvrkalealpsn..gpvvVHCsaGvgRtgtfialdllldqleke..ggvdvleavkllrsqRpgmvqtpeqyrflye
|
|||||||||
0040438 | (Phosphotyrosine protein) phosphatases II | 2-137 | 2.4e-32 | 107.9 | In-house | 100-270 (317) | alignment | ||
Range on Protein: 2-137
Range on HMM: 100-270/317.0
ADFWQMVWETGSGHIVMVNDDQKNK----------------------------------------ETAPPSTREISHYQFTSWKEKTTP-NVALFVGFVV
.|||.|||| |...|||... .. . . .|.. |...|.| . ..| . |.. |.
edFwrmvweqgvtvivmLteleelgrekcaqYwplgetltygdftvtllseeelagitlrtlevedlgdsesrtvthfhytgWpdhgvppspdllldfle
ASREVSKkyeqEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEESKtsVVDLFEVAKRLRQARCGIISSLQHYNFIYQ
| ||. . ... ||.||||.| | ||.|.|... .. |. . ||..|. |.||..|.|.. ....| |.|.
avreale....dpggpvlVHCsaGvgRtGtfiaaylmleqlekeg..gvdveeavkelreqRpgavqtpeqyrflyd
|
|||||||||
0045450 | (Phosphotyrosine protein) phosphatases II | 2-137 | 2.7e-32 | 108.2 | In-house | 121-298 (307) | alignment | ||
Range on Protein: 2-137
Range on HMM: 121-298/307.0
ADFWQMVWETGSGHIVMVNDDQKNKET------------------------------------------APPSTREISHYQFTSWKEKTTP-NVALFVGF
.|||.|.|| |...|||.... .. .|.. |...|.| . ..| ... .. |
edFwrmlweqgvtvivmltelvelgrekcaqywPdegeeltygnftvtllseehldgytvrtlevtdldgtgesrtvthfhytgwpdhgvppsfeelldf
VVASREVSKKYeqEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEESKTSV-VDLFEVAKRLRQARCGIISSLQHYNFIYQ
. . |.. ... |. ||.||||.| | ||.|.|... | .|. .| |||.|. |.||. |.|.. ....| |.|.
ieevrkaleel..pkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrflye
|
|||||||||
0043336 | (Phosphotyrosine protein) phosphatases II | 2-137 | 1.8e-31 | 105.0 | In-house | 102-271 (278) | alignment | ||
Range on Protein: 2-137
Range on HMM: 102-271/278.0
ADFWQMVWETGSGHIVMVNDDQKNKE---------------------------------------TAPPSTREISHYQFTSWKEKTTP-NVALFVGFVVA
.|||.|||| |. .|||.... .. . . .|.. ||....| . ..| ...|.. |. |
edFwrmvwelgvttivmLtelvelgrvkcaqYwpggsltygdftvtllkeehlddytvrtlevtnlgdgesrtvthyhylgwpdhgvpeslsllldflka
SREVSKkyeqEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEESKtsVVDLFEVAKRLRQARCGIISSLQHYNFIYQ
||. . .. ||.||||.| | ||.|.||.. .. | . |||.|. |.||. |.|.. ....| |.|.
vreale....dsngpvlVHCsaGvgRTGtfialyllleqlekeg..gvdleeavkelreqRpgavqtpsqyrflye
|
|||||||||
0039614 | (Phosphotyrosine protein) phosphatases II | 2-137 | 4.3e-31 | 103.9 | In-house | 115-283 (297) | alignment | ||
Range on Protein: 2-137
Range on HMM: 115-283/297.0
ADFWQMVWETGSGHIVMVNDDQKNKE------------------------------------TAPPSTREISHYQFTSWKEKTTP-NVALFVGFVVASRE
.|||.|||| |. .|||... .. | .|.. |.|.|.| . ..| ...|. |. . ||
edFwrmvweqgvtvivmLtklvelgrkcaqywpeeggtygdftvtllkvehldgytvrtlevtnngesrtvthfqytgwpdhgvppslellleflelvre
VSKKYeqEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEESktSVVDLFEVAKRLRQARCGIISSLQHYNFIYQ
. ... .|. ||.||||.| | ||.|.|... .. |. ||..|. |.||..|.|.. ....| |.|.
alael..pkggpvlVHCsaGvgRtGtfiaaylmleqleke..ggvdvleavkelreqRpgavqtpsqyrflyd
|
|||||||||
0045098 | (Phosphotyrosine protein) phosphatases II | 2-137 | 7.5e-30 | 99.7 | In-house | 78-266 (278) | alignment | ||
Range on Protein: 2-137
Range on HMM: 78-266/278.0
ADFWQMVWETGSGHIVMVNDDQKNK--------------------------------------------ETAPPSTREISHYQFTSWKEKTTPNVALFVG
||||.|.|| |. .|||... . .. | . .|.. |.....| . ..|. .
adfwrmlwelgitvivmltelvelgrekcaqywpeggsltygdftvtllseevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilks
FVVASREVSKKYE------------QEKDAPVIVHCSDGQGFTGVFVALDIGVRSHeeskTSVVDLFEVAKRLRQARCG-IISSLQHYNFIYQ
| . ... . .. .... ||.|||| | | ||..||... . ..|||.|. | ||. |.| .. .|..|.|.|.
flellefirealkllaslllsslllldsggpvlVHCsaGvgRtGtlvaaylmlell....eggvdlleavkelrsqRpglavqnleqyrflye
|
|||||||||
0042113 | (Phosphotyrosine protein) phosphatases II | 2-137 | 1.6e-29 | 98.5 | In-house | 66-237 (245) | alignment | ||
Range on Protein: 2-137
Range on HMM: 66-237/245.0
ADFWQMVWETGSGHIVMVNDDQKNKET----------------------------------------APPSTREISHYQFTSWKEKTTPN-VALFVGFVV
.|||.|.|| |. .|||.... .. . .||. ||....| . ..|. ..|.. |.
edfwrmlwelgittivmLteeeelgrvkcaqywplgesltygdftvtllseehlddytvrtlevtnlgddesrevihyhylpwpdhgvpdllellldfle
ASREVSKKyeqEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEesKTSVVDLFEVAKRLRQARCGIISSLQHYNFIYQ
. |.. .. .. ||.||||.| | ||.|.|... .. | |. |.|.|. |.||. |.|.. ....| |.|.
fvrkalae...dsngpvlVHCsaGvgRtGtfiaaylmleqle..kelgvsleeavkelrsqRpgavqtpsqyrflye
|
|||||||||
0040439 | (Phosphotyrosine protein) phosphatases II | 2-137 | 1.9e-29 | 98.5 | In-house | 68-240 (249) | alignment | ||
Range on Protein: 2-137
Range on HMM: 68-240/249.0
ADFWQMVWETGSGHIVMVNDDQKNK----------------------------------------ETAPPSTREISHYQFTSWKEKTTP-NVALFVGFVV
.|||.|.|| |...|||..... .. . ...|.. |.|.|.| . .| ... .. |.
edfwrmlwelgitvivmLtslvelgrekcaqywplggsleygdftvtllsvevkddytvrtleltnlydgesrtvlhiqytdwpdhgvppsfedlldfie
ASREVSKKYeqEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEesKTSVVDLFEVAKRLRQARCGIISSLQHYNFIYQ
| |.. ... .|. ||.||||.| | ||.|.|... .. | |. |||.|. | ||..|.|.. ....| |.|.
avrkaleel..pkggpvlVHCsaGvgRtGtfiaaylmleqle..kelgvdleeavkllrsqRpgavqnpeqyrflye
|
|||||||||
0037934 | (Phosphotyrosine protein) phosphatases II | 2-137 | 1.1e-26 | 89.4 | In-house | 58-236 (243) | alignment | ||
Range on Protein: 2-137
Range on HMM: 58-236/243.0
AD----FWQMVWETGSGHIVMVNDDQKNKET---------------------------------------APPSTREISHYQFTSWKEKTTPN-VALFVG
.| ||.|.|| |...|||..... .. ... ||.. ||....| . ..|. .. ..
eddlasfwrmlwelgitvivmltelvElgrekcaqywpgevtygdftvtllseehlddytvrtlllenldlddltrlvihyhylpwpdhgvPdspedlld
FVVASREVSKKY----EQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHeesktSvVDLFEVAKRLRQARCG-IISSLQHYNFIYQ
|. . ||. ... .. ||.|||| | | ||...|... . . |||.|. |.||. |.| .. ....| |.|.
fldevrefieellsllaldsggpvlVHCsaGvgRtGtliaaylmllll.....g.vdleeavkllreqRpgkavqtpsqyrflye
|
|||||||||
0041856 | (Phosphotyrosine protein) phosphatases II | 2-137 | 9e-23 | 76.2 | In-house | 48-165 (182) | alignment | ||
Range on Protein: 2-137
Range on HMM: 48-165/182.0
ADFWQMVWETGSGHIVMVNddqKNKETAPPSTREISHYQFTSWKEKTTPNVALFVGFVVASREvskkyeqeKDAPVIVHCSDGQGFTGVFVALDIGVRSh
|||..|..| | ..||... . .|.. .|....| ..|.. .. |. . .| .. ||.|||| | | ||..||... .
adflrmlkelgittivnlt...eelywpellerlgiqylylpwpDhgvpdldelldfieevle........eggpvlVHCsaGvgRtgtlvaaylmkkl.
eesktSvVDLFEVAKRLRQARCGIISSLQHYNFIYQ
. |.|.|. | .|..|.|.. ....| |...
.....g.vsleeavklvrsrRpgmvitpnqyfflql
|
|||||||||
0051429 | (Phosphotyrosine protein) phosphatases II | 2-137 | 2.3e-19 | 65.6 | In-house | 36-219 (272) | alignment | ||
Range on Protein: 2-137
Range on HMM: 36-219/272.0
ADFWQMvWETGSGHIVMVNDDQ---KNK----------------------ET----------------------------APPSTREISHYQFTSWKEKT
||||.. .| | .||.. .. ..| . . .||. |...|.|
adfwrl.kelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseellldyilrellltlllsagearevmhlhytdwpdhg
TPN--VALFVGFVVAsrevskkyeqekDAPVIVHCSDGQGFTGVFVALDIGVrsHEESKTSVVD--------LFEVAKRLRQARCGIISSLQHYNFIYQ
.| . .. .. . . ||.|||| | . ||..|||.. . . |.. .|| |.|. ..||..| |.. . ..| |.|.
vpqeallellellld............ggpvlvHCsaGkdRTGtvvalllll..lgvsletivddYlltnlyleeaveelraqrpgavqteeqylflye
|
|||||||||
0044763 | (Phosphotyrosine protein) phosphatases II | 2-137 | 3.1e-17 | 58.2 | In-house | 38-165 (178) | alignment | ||
Range on Protein: 2-137
Range on HMM: 38-165/178.0
ADFWQMVWETGSGHIVMVNDDQKN---KETAPPSTREISHYQFTSWKEKTTPN-VALFVGFVVASREVSkkyeQEKDAPVIVHCSDGQGFTGVFVALDIG
||......| | .|||...... . |. . ... .|... . ..|. . | || . .|. .||. ||.|||| | | .|..||...
addlellkelgithivnlteelelgflkcdpywpeeagiqylhipipDhgvpdllehflefvefieeal....dekggpvlVHCsaGvgRsgtlvaaylm
VRSheesktSVvDLFEVAKRLRQARCgIISSLQHYNFIYQ
. .. .|.|. ...|..|. |. . .....|.
kkl......gl.sleeaielvrerRp.ivpnpgqlrqLye
|
|||||||||
0049772 | (Phosphotyrosine protein) phosphatases II | 3-136 | 4.4e-16 | 55.0 | In-house | 99-273 (314) | alignment | ||
Range on Protein: 3-136
Range on HMM: 99-273/314.0
DF----------WQMV--WETGSGHIVM---------------------VND----------------DqknKET--APPSTREISHYQFTSWKEKTTPN
|| |.|| .. . ||| .. .|. .. .|.. .| . . ..|
dfreepvlyyngwrmvlrgdlnvrdivmsrdevladelsrLdaAlgKtpllildgngneptaadlellk...eelydpelferlgikylripvpDgsapl
VALFVGFVVASREVskkyeqEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEesktsvVDLFEVAKRLRQARC-----GIISSLQHYNFIY
. | |. . .|. .|. ||.|||..| | ||.||.... .. . |.| |. ...|..| | | .|..| ||.
ledfdeflefieea......dkggpvlvHCkaGkgRtgtfvvaaylmkllg......vsleealedvrlkRpinpnpgfieqleqyefil
|
|||||||||
0036282 | (Phosphotyrosine protein) phosphatases II | 4-137 | 1.4e-24 | 82.2 | In-house | 28-164 (174) | alignment | ||
Range on Protein: 4-137
Range on HMM: 28-164/174.0
FWQMVWETGSGHIVMVNDDQKNK---------ETAPPSTREISHYQFTSWKEKTTPNVALFVGFVVASREVSKKyeqEKDAPVIVHCSDGQGFTGVFVAL
||.|..| |. ..||... . .. |. .|.. .|... | ..|... . || . .|. .. .. ||.|||| | | ||..||.
fwemlkelgittvvmlleekelglykcinywpelredlerlgiqylylpwpDhgvpdlsillefvkfveealse...dpggpvlVHCsaGvgRtGtlvaa
DIGVRSHEeskTSVVDLFEVAKRLRQARCGIISSLQHYNFIYQ
.. | .. .|.|| ... ..||. |.|.. . ..| |.|.
ylmlrgll...eslvdaldlvrelRlqrpgmvqtpsQyrflyy
|
|||||||||
0048076 | (Phosphotyrosine protein) phosphatases II | 7-137 | 1.1e-14 | 49.8 | In-house | 24-137 (145) | alignment | ||
Range on Protein: 7-137
Range on HMM: 24-137/145.0
MVWETGSGHIVMVnddqknKETAPPSTREISHYQFTSWKEKTTPNV-ALFVGFVVASREVSKKyeqekDAPVIVHCSDGQGFTGVFVALDIGVRsheesk
. .. | .... . . . .|.. .|....| ..|. .|. |. . .|. |. . ||.|||| | | ||..||... .
llkdlgittvlnl......tselellerlgiqylylpwpDhgvpdllellleflefieealke.....ggpvlVHCsaGvgRtgtlvaaylmll......
TSvVDLFEVAKRLRQARCGIISSLQHYNFIYQ
. |.|.|. ...|..| |.. . ....|.|.
lg.vsleealelvrsqrpgavpnpgqlrflye
|
|||||||||
0048179 | (Phosphotyrosine protein) phosphatases II | 9-137 | 2.4e-14 | 48.8 | In-house | 26-139 (144) | alignment | ||
Range on Protein: 9-137
Range on HMM: 26-139/144.0
WETGSGHIVMVNDDqknkETAPPSTREISHYQFTSWKEKTTPNV-ALFVGFVVASREVskkyeQEKDAPVIVHCSDGQGFTGVFVALDIGVrsheesKTS
.. | .... .... . .||. .|....| .|. .|. |. . .|. .|.. ||.|||| | | ||..||... . |
kklgittvinltee....yepefleregiqylhlpwpDhgvpdllellleflefieea.....leeggpvlVHCsaGvgRtgtlvaaylmk......klg
vVDLFEVAKRLRQARCGIISSLQHYNFIYQ
..|.|. ...|..|.|.. . ....|...
.lsleealalvrsrrpgavpnpgqlrfLle
|
|||||||||
subfamily_Auxilin_pd | Subfamily Auxilin | 13-120 | 2.3e-07 | 23.7 | In-house | 48-147 (166) | alignment | ||
Range on Protein: 13-120
Range on HMM: 48-147/166.0
SGHIVMVNDDQKNKETAPPSTReISHYQftsWKEKTTPNVALFvgfVVASREVSKKYEQEKDAPVIVHCSDGQGFTGVFVA-LDIGVRSHEESkTSVVDL
... ...| |....||..|.| ..... | .. .||. . | .|.. . .... |.||| ||. ..| |. | . .| .|. | |.|
pekylvynlsqrtyrtaklssr.vveag...wparraPnLesl...vevcrnlyswlkkdpknvvvvhckDGraasavlvsallvfcrllsep.esavrl
FEVaKRLRQ
| | ||| .
fsv.krlpi
|
|||||||||
subfamily_Cele-PTP-7_pd | Subfamily Cele-PTP-7 | 24-131 | 1.3e-09 | 31.9 | In-house | 178-276 (302) | alignment | ||
Range on Protein: 24-131
Range on HMM: 178-276/302.0
KNKETAPPSTREISHYQFTSWKEKTTPNVALfvgfvvASREVSKKYEQEKdAPVIVHCSDGQGFTGVFVALDIGVRSHeeSKTSVVDLFEVAKRLRQARC
||... . .. .|..| .. .|. | .. .. | | | |.|||| | | || .||. |. || | || .. . .|| |
knekkkkkvkktvdilafsawpdhGapkeay......taldilkfcesyk.knvlvhcsaGvGrtGtlvaikyGiqlc..skkkvtdllsivlpvrqcry
GIISSLQH
| . . |
Gavqdeqq
|
|||||||||
subfamily_Nvec-PTP-3_pd | Subfamily Nvec-PTP-3 | 25-137 | 8e-82 | 268.2 | In-house | 85-197 (198) | alignment | ||
Range on Protein: 25-137
Range on HMM: 85-197/198.0
NKETAPPSTREISHYQFTSWKEKTTPNVALFVGFVVASREVSKKYEQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEESKTSVVDLFEVAKRLRQARCG
|. |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
nnttappstreishyqftswkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcg
IISSLQHYNFIYQ
|||||||||||||
iisslqhynfiyq
|
|||||||||
subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 25-137 | 4.2e-20 | 66.8 | In-house | 170-277 (290) | alignment | ||
Range on Protein: 25-137
Range on HMM: 170-277/290.0
NKETApPSTREISHYQFTSWKEKTtpNVALFVGFVVASREVSKKYEQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEesKTSVVDLFEVAKRLRQARCG
||..| ..... .||.|.|... .|. . ... .|. |. .. . ...|||||. | ..||.|..... . .. |.|.|.| |..|. . |
nknsa.gakqsvtqyqitnwdstg..kvtnpqtillvieemyktqrkrgntsivvHCSdtvgrsavfcaaattinkck..tegvidvfqvlksqRiqkpg
IISSLQHYNFIYQ
. . |.|..|.|
svqtvqqyqgifq
|
|||||||||
subfamily_Cele-PTP-15_pd | Subfamily Cele-PTP-15 | 25-136 | 4.3e-08 | 27.5 | In-house | 158-263 (285) | alignment | ||
Range on Protein: 25-136
Range on HMM: 158-263/285.0
NKETAPPSTREISHYQFTSWKEKTTPNVALFVgfVVASREVsKKYeQEKDAPVIVHCSDGQGFTGVFVALDIG-VRSHEESKtsvVDLFEVAKRLRQARC
| | | . | | | .. .|. | . . . | || . |. |. |||| | | | || .| .| |. . ...... . .| |
ntedasseplymnhvqvpwwpdqlapedarpm..ielykwv.kkv.npkekpicvhcsagvgrtatfvgidyatirimenpn...iemldivremramrf
GIISSLQHYNFIY
. | .. |.|
qavqshmqflfly
|
|||||||||
subfamily_Ptp69D_pd | Subfamily Ptp69D | 26-137 | 1.2e-21 | 72.2 | In-house | 174-280 (307) | alignment | ||
Range on Protein: 26-137
Range on HMM: 174-280/307.0
KETAPPSTREISHYQFTSWKEKTTPNVALfvGFVVASREVSKKYEQEkDAPVIVHCSDGQGFTGVFVALDIGVRSHEESKtsVVDLFEVAKRLRQARCGI
. . . .|.. |..|.||. . |.|| | . ..| . |... .|..|||| | | .|.|||||. . .. . ||.||. | ||. | .
esgevedsrkvvqyhytgWkDskvPevar..gllklieqvrelykln.rsPivvhCsaGvgrsgifvaldsllqqlkaed..kvdifetvkdLrsqRnll
ISSLQHYNFIYQ
. ||. | |.|.
vqsleqYvflyr
|
|||||||||
subfamily_PTPRG_pd | Subfamily PTPRG | 26-137 | 7.9e-20 | 65.6 | In-house | 174-281 (563) | alignment | ||
Range on Protein: 26-137
Range on HMM: 174-281/563.0
KETAP-PSTREISHYQFTSWKEKTTPNVALFVGFVVASREVSKKyeqEKDAPVIVHCSDGQGFTGVFVALDIGVRshEESKTSVVDLFEVAKRLRQARCG
|.. . ... .|..|.| ....|. .|.| | .. ..| .. |..|||| | | ||....|| .. . . ..|..|...|..| |
kkkkqcdteklvrqyhytkWPdhgvPehslpvLifvkkssaank...aeaGPivvHcsaGvgrtGtyivldtllk..qiqqenavnvfgflkhiraqRnf
IISSLQHYNFIYQ
.. . | |...
lvqteEqYiflhd
|
|||||||||
subfamily_PTPRA_pd | Subfamily PTPRA | 27-137 | 8e-19 | 62.7 | In-house | 184-289 (330) | alignment | ||
Range on Protein: 27-137
Range on HMM: 184-289/330.0
ETAPPSTREISHYQFTSWKEKTTPNVAlfVGFVVASREVSKKYEQEKDaPVIVHCSDGQGFTGVFVALDIGVRS-HEEsktSVVDLFEVAKRLRQARCGI
.| ..| .. . |||| . | . .| . ..| |. .|. . |..|||| | | || |..|| . . | .||.||. ||||. |. .
atrekksrlvrqfhftswPdvGvPfep..iGmlkllkkvkklnqqsag.pivvhcsaGvGrtGtfivldavlervkae...rkvdvfefvkrlrlqrpqm
ISSLQHYNFIYQ
. ... |.|||.
vqtdeqyefiyk
|
|||||||||
subfamily_Anemone-PTP-3_pd | Subfamily Anemone-PTP-3 | 28-137 | 2.7e-81 | 266.5 | In-house | 89-198 (199) | alignment | ||
Range on Protein: 28-137
Range on HMM: 89-198/199.0
TAPPSTREISHYQFTSWKEKTTPNVALFVGFVVASREVSKKYEQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEESKTSVVDLFEVAKRLRQARCGIIS
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
tappstreishyqftswkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiis
SLQHYNFIYQ
||||||||||
slqhynfiyq
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 28-137 | 5.1e-25 | 83.6 | Pfam-A | 126-231 (235) | alignment | ||
Range on Protein: 28-137
Range on HMM: 126-231/235.0
TAPP-STREISHYQFTSWKEKTTP-NVALFVGFVVASREVSkkyeQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEESKTsvVDLFEVAKRLRQARCGI
.. . .||......|.|.....| .. .. .. . .. . ..|..||.||||.| | ||.|||||| ... |. .. ||.... |.||. |.|.
kkeesekrevkqlhytnWpdhgvpespkslldlirkveksk....eaksgpvvVhCsaGvgRtgtfvaldilleqleaeee..vdvlqivkelRkqRpgm
ISSLQHYNFIYQ
..||. | |.|.
vqsleqYiflyk
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 28-137 | 5.1e-25 | 83.6 | In-house | 126-231 (235) | alignment | ||
Range on Protein: 28-137
Range on HMM: 126-231/235.0
TAPP-STREISHYQFTSWKEKTTP-NVALFVGFVVASREVSkkyeQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEESKTsvVDLFEVAKRLRQARCGI
.. . .||......|.|.....| .. .. .. . .. . ..|..||.||||.| | ||.|||||| ... |. .. ||.... |.||. |.|.
kkeesekrevkqlhytnWpdhgvpespkslldlirkveksk....eaksgpvvVhCsaGvgRtgtfvaldilleqleaeee..vdvlqivkelRkqRpgm
ISSLQHYNFIYQ
..||. | |.|.
vqsleqYiflyk
|
|||||||||
subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 28-137 | 4.7e-21 | 70.2 | In-house | 169-274 (318) | alignment | ||
Range on Protein: 28-137
Range on HMM: 169-274/318.0
TAPPSTREISHYQFTSWKEKTTPNVAlfVGFVVASREVSKKYEQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEESKtsVVDLFEVAKRLRQARCGIIS
| ..|.. |..||| .. .|. . .... |.||| .... |..|||| | | ||||.|.|| .. .. . .||.|.. |.||. | ..
teeeesrqvrqyhytsWpdegvpesg..aslldlvrqvskaqqksgagpivvhCsaGvGrtGvfiavdillerikaea..lvDvfqtvkqlreqrnlmvq
SLQHYNFIYQ
. |.|||.
tedqyefiyd
|
|||||||||
subfamily_Cele-PTP-18_pd | Subfamily Cele-PTP-18 | 29-137 | 2.7e-06 | 21.4 | In-house | 181-281 (305) | alignment | ||
Range on Protein: 29-137
Range on HMM: 181-281/305.0
APPSTREISHYQFTSWKEKTTPNVALFVGFVVASREVSKkyeqekdAPVIVHCSDGQGFTGVFVALDIGVRSHeESKTSVVDLFEVAKRLRQARCGIISS
. ..| ..|| . | .. | | . ... .|| |..|||| | | || | |. . . . | . ...|. | | .
pgekarkvthyhwidwpdrgvpaadlailellekarpsk.......gpivvhcsagigrtgsvvmleyildql.lagqiiedtdkilqkireqrnnsiqt
LQHYNFIYQ
. | |..|
daqylfvhq
|
|||||||||
subfamily_PTPRD_pd | Subfamily PTPRD | 30-137 | 1.3e-23 | 78.5 | In-house | 173-275 (564) | alignment | ||
Range on Protein: 30-137
Range on HMM: 173-275/564.0
PPSTREISHYQFTSWKEKTTPNVAlfVGFVVASREVSKKYeQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEEskTSVVDLFEVAKRLRQARCGIISSL
..||. ...|||| .. |. | ... |.|.. ... |..|||| | | ||.|...|. .. .| .||.... |.||. | .. .
ssesreVrqFhFtsWPdhgvpesa..tslLdlirkvraln.epdagPivVhCSaGVGRTGtfividamlerike..ektvDiyqyvkalrkqRnamVqte
QHYNFIYQ
. | ||..
eQYiFihe
|
|||||||||
subfamily_CG7180_pd | Subfamily CG7180 | 30-137 | 2.1e-22 | 74.1 | In-house | 176-284 (296) | alignment | ||
Range on Protein: 30-137
Range on HMM: 176-284/296.0
PPSTREISHYQFTSWKE-KTTPNV-ALFVGFVVASREVSKKY-EQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEesKTSVVDLFEVAKRLRQARCGII
|| . ..|.| |. . | . . .. .. | . .| |... .||.|..|||.. .||..|.|. . | |. ||.|| .|.||. | ...
kaetRivklfqlteWeledkvPlstnalielrrrvrlwrekvdedpeegPvvvvssdGasRsGvylaidanlelve..keeevdvFeavktlrrsRpqLv
SSLQHYNFIYQ
. ..| .||.
enveeYkyiYd
|
|||||||||
subfamily_PTPN6_pd | Subfamily PTPN6 | 30-137 | 5e-20 | 66.7 | In-house | 182-291 (306) | alignment | ||
Range on Protein: 30-137
Range on HMM: 182-291/306.0
PPSTREISHYQFTSWKEKTTPNVAL-FVGFVVASREVSKKYEQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEESKTSV-VDLFEVAKRLRQARCGIIS
..||. .|.|.|| .. .|. .. |. .. ... |... |..||||.| | || |. .|| .. |.... . .|. .. | .|. | |..
kkeerevfqyhfksWPdhgvpkdpgavLdfledvnrkqeeleeaeagpivvhCsaGiGRtGtfiviDillkliekkgldadidiqklvksvreqrsglvq
SLQHYNFIYQ
| |.|.|.
teqqykfvyk
|
|||||||||
DSPc_SM00195 | 31-137 | 2.1e-23 | 78.4 | In-house | 155-256 (263) | alignment | |||
Range on Protein: 31-137
Range on HMM: 155-256/263.0
PSTREISHYQFTSWKEKTTP-NVALFVGFVVASREVSKKYeqekDAPVIVHCSDGQGFTGVFVALDIGVRSHEESKTsvVDLFEVAKRLRQARCGIISSL
||.. .||...|... .| . .. .. | .. ... ..|..||||.| | ||.||..|| ... || |. ||.||. |.||. |.|....|
eetrkvtqyqyknWpdhgvpdstksvlellravkksksts....sgpivVhCsaGvgRtgtfvtidiilskleeekk..vdifeivkelRkqRpgmvqtl
QHYNFIYQ
..| |||.
eqYlfiye
|
|||||||||
PTPc_SM00194 | 31-137 | 2.1e-23 | 78.4 | In-house | 155-256 (263) | alignment | |||
Range on Protein: 31-137
Range on HMM: 155-256/263.0
PSTREISHYQFTSWKEKTTP-NVALFVGFVVASREVSKKYeqekDAPVIVHCSDGQGFTGVFVALDIGVRSHEESKTsvVDLFEVAKRLRQARCGIISSL
||.. .||...|... .| . .. .. | .. ... ..|..||||.| | ||.||..|| ... || |. ||.||. |.||. |.|....|
eetrkvtqyqyknWpdhgvpdstksvlellravkksksts....sgpivVhCsaGvgRtgtfvtidiilskleeekk..vdifeivkelRkqRpgmvqtl
QHYNFIYQ
..| |||.
eqYlfiye
|
|||||||||
subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 31-137 | 1.8e-21 | 71.7 | In-house | 182-284 (298) | alignment | ||
Range on Protein: 31-137
Range on HMM: 182-284/298.0
PSTREISHYQFTSWKEKTTPNVALFVgfVVASREVSKKYEQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEesKTSVVDLFEVAKRLRQARCGIISSLQ
..||. . .|||| .|..|..| | . |.| .. .| ...||||.||.| | .| |.|.| . . | .|||.|.| |.||. |.|.. . .
ekerevrqlhftsWpdkgvpenatsv..ldllrkvrasqqqagnkpvivqCsaGvgRsGtfiaidsvlervk..keqvvDvfqvvkvlRkkrpgavqtee
HYNFIYQ
.| |||.
qYvfiye
|
|||||||||
subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 31-137 | 1.7e-19 | 65.1 | In-house | 174-278 (297) | alignment | ||
Range on Protein: 31-137
Range on HMM: 174-278/297.0
PSTREISHYQFTSWKEKTTPNVALFVGFVVASREVSKKYEQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEesKTSVVDLFEVAKRLRQARCGIISSLQ
..| . |||..| .|. .. .. || |...|....|..|||. | | |||....| | . .. ||.|.. |.||| | .. .
karrvvkqyqfveWPdkaverkdsassllklisevrkdfsqnaegPllvhclaGvGrtgvlltidsvvaeak..rekevdifglvkklrqerpylvqtke
HYNFIYQ
.|.|.|.
qykfvyv
|
|||||||||
subfamily_PTPN3_pd | Subfamily PTPN3 | 31-135 | 5.2e-17 | 56.7 | In-house | 168-267 (280) | alignment | ||
Range on Protein: 31-135
Range on HMM: 168-267/280.0
PSTREISHYQFTSWKEKTTPNV-ALFVGFVVASREVSkkyeQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEESKTsvVDLFEVAKRLRQARCGIISSL
|.| . |...| ... |. | |. || |.. . |. ||.|||| | | |||...|.. . |... | .. ...|. | .. .
keerkilqlqylaWpdhgvPddsadflefvervrklr....sgkeePvvvhCsaGigrtGvlilletalalieaaep..vypldivrtmrdqramlvqta
QHYNFI
. |.|.
sqykfv
|
|||||||||
subfamily_PTPN9_pd | Subfamily PTPN9 | 31-136 | 5.2e-17 | 56.8 | In-house | 170-283 (297) | alignment | ||
Range on Protein: 31-136
Range on HMM: 170-283/297.0
PSTREISHYQFTSWKEKTTPNVAL-FVGFVVASRE--------VSKK-YEQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEEskTSVVDLFEVAKRLRQ
.|...|.||.|| . .|. | .. .. . || .... . .. |..|||| | | || |..||| . || ...||..|. |.||.
eesrkvthfqflsWPdyGvPssaaslldvlekvrekqalavkelgdewkghpsgPPivvhcsaGiGrtGtfitldiclsrlee..vgtvdvvetvkllrt
ARCGIISSLQHYNFIY
| | . |.| |
qrafsiqtpeqyefcy
|
|||||||||
subfamily_PTPN23_pd | Subfamily PTPN23 | 31-137 | 1.3e-16 | 55.3 | In-house | 168-274 (288) | alignment | ||
Range on Protein: 31-137
Range on HMM: 168-274/288.0
PSTREISHYQFTSWKEKTTPN-VALFVGFVVASREVSKKYEQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHeESKTSVVDLFEVAKRLRQARCGIISSL
....|| |.||| | |. .. |. . .. .. ... ..|..|||| | | |||| . || | . ..|. .| .|||. | ..
davksvshlqltsWpelGvPasPetllqfldevesayeavqrksktPlvvhCsaGvgRtgvfalvyaavrel.ekgnglldiiqvvsrlreqRrfmvqek
QHYNFIYQ
....| |.
eqlkfsye
|
|||||||||
subfamily_PTPN13_pd | Subfamily PTPN13 | 31-137 | 4e-16 | 54.1 | In-house | 163-263 (273) | alignment | ||
Range on Protein: 31-137
Range on HMM: 163-263/273.0
PSTREISHYQFTSWKEKTTPNVAL-FVGFVVASREVSKkyeqeKDAPVIVHCSDGQGFTGVFVALDIGVRSHEESKtsVVDLFEVAKRLRQARCGIISSL
.||..| .|..| . .|. |. .. || |.. . . .|..|||| | | .|.....|. . | | .|. |. ..||. | |.. .
gesrevahlnfvkwPdhgvPssaaellqfvaevrrlqt.....dagPivvhcsaGiGrsGtlitidvvlglierdk..efdvkeivrklreqrqgvvqtk
QHYNFIYQ
. | |.|.
dqyifvyk
|
|||||||||
subfamily_PTPRN_pd | Subfamily PTPRN | 31-136 | 4e-15 | 50.3 | In-house | 184-285 (297) | alignment | ||
Range on Protein: 31-136
Range on HMM: 184-285/297.0
PSTREISHYQFTSWKEKTTPNVALfvGFVVASREVSKKYEQeKDAPVIVHCSDGQGFTGVFVALDIGVRSHEEsKTSVVDLFEVAKRLRQARCGIISSLQ
|| .. . | ||.|...| | .. | | | | . .|..|||||| | |||....|. . .|. . ||. | |.. . .
setrtvtqfhflswpeegvPasak..sllefrrkvnksyrG.rscpivvhcsdGaGrtGvyilidlvlnrllk.Gvkeidiaatlehlrdqrpglvktkd
HYNFIY
..|..
qfefal
|
|||||||||
subfamily_PTPN1_pd | Subfamily PTPN1 | 31-136 | 7.6e-15 | 49.4 | In-house | 159-264 (290) | alignment | ||
Range on Protein: 31-136
Range on HMM: 159-264/290.0
PSTREISHYQFTSWKEKTTPNV-ALFVGFVVASREVSKKyeQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEESK-TSVVDLFEVAKRLRQARCGIISS
||||.|. .|.| . . |. | |. |. || ... |...||| | | .| |. .| . |... .| ||. .| ||. | |.|
qetreilhfhyttwpdfgvpespaaflkflfkvresGsl..ssdvGpavihcsaGiGrsGtfclvdtclvliekkddlssvdikkvllelrkyrlGliqt
LQHYNFIY
. .| |
adqlrfsy
|
|||||||||
subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 31-136 | 6e-14 | 46.9 | In-house | 175-281 (325) | alignment | ||
Range on Protein: 31-136
Range on HMM: 175-281/325.0
PSTREISHYQFTSWKEKTTPNV-ALFVGFVVASREVSKKYEQ--EKDAPVIVHCSDGQGFTGVFVALDIGVRshEESKTSVVDLFEVAKRLRQARCGIIS
|| . .|. ||.. ... | .. .. .||.. . .|..||||.| | ||||..| . . . | ||.|.. |.||. | ..
GetrsvkqfqlqswddmGvqkrpatlisilqlvkavservtantkastpilvhcsaGvGrtGvfislysala..kvieesrvdifgfvkklrkdrpsmve
SLQHYNFIY
. | .||
tvdqyiliy
|
|||||||||
subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 32-136 | 1.6e-24 | 81.6 | In-house | 176-276 (305) | alignment | ||
Range on Protein: 32-136
Range on HMM: 176-276/305.0
STREISHYQFTSWKEKTTPNVAlfVGFVVASREVSKKYEQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHeeSKTSVVDLFEVAKRLRQARCGIISSLQH
.| ...||.|.| .. |. | .. ..| |.....|. |..||||.| | ||||.|.|| . | |||.||| |.||. | .....|..
esrtvlqyqltdWPdhGvpqfa..tsllslikrvqkdqkkdkgvpllVhCsagvgRtGvfiavdialerl..kkEevvdvfevlkqlRskrmkmvqtldq
YNFIY
|.|..
Yvflh
|
|||||||||
subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 32-137 | 2.6e-24 | 80.9 | In-house | 176-277 (319) | alignment | ||
Range on Protein: 32-137
Range on HMM: 176-277/319.0
STREISHYQFTSWKEKTTPNVALFVgfVVASREVSKKYEQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHeeSKTSVVDLFEVAKRLRQARCGIISSLQH
|||..|.|.|.| .. |. |. . . ... | |.... |..||||.| | || |..||. . .. .|.|.|....||| | ... .
etRevkhfqyteWpdhdvPekatsl..ldllkrirksrektqsgPivvhCsaGvGRtGtfivldamlerv..keegvlDvfstvsrlRtqRnimvqrpeq
YNFIYQ
|.|||.
Ykfiye
|
|||||||||
subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 32-137 | 3.3e-21 | 70.5 | In-house | 150-258 (270) | alignment | ||
Range on Protein: 32-137
Range on HMM: 150-258/270.0
STREISHYQFTSWKEKTTPNVAL----FVGFVVASREVSKKYEQEKD-APVIVHCSDGQGFTGVFVALDIGVRSHEESKtsVVDLFEVAKRLRQARCGII
..|.. |.....| ... |. . . |.| . .. .. |..||||.| | ||...||||.|| ||.| ||. .. ..||. |. ..
eerrlvHfwyntWpdhgvpreedsslstdqllkmlravrrsekeldkaePllvHcsaGvgRtGtlialDiavrlLeetk..kvdvlaiieelRkdRmalv
SSLQHYNFIYQ
. ..|.|.|.
qhpeqyeflyk
|
|||||||||
subfamily_PTPRK_pd | Subfamily PTPRK | 32-137 | 4.1e-21 | 70.1 | In-house | 171-271 (314) | alignment | ||
Range on Protein: 32-137
Range on HMM: 171-271/314.0
STREISHYQFTSWKEKTTPNVAlfVGFVVASREVSKKYEQeKDAPVIVHCSDGQGFTGVFVALDIGVRSHEesKTSVVDLFEVAKRLRQARCGIISSLQH
.||. ..||..| . .|. | |.. |.| |. |. .. ...|||| | | ||.|.|.|| . | . .|||.|...| ||. . .. .
eirevrqfqflgWpdhdvPvsa..tgllklvrrvkksqee.eaGrivvhCsaGaGrtGtfiaidivldmie..regvvdvfnavktlrsrkvnmveteeq
YNFIYQ
|.|||.
ykfiyd
|
|||||||||
subfamily_PTPRB_pd | Subfamily PTPRB | 32-137 | 1.7e-20 | 68.3 | In-house | 177-279 (293) | alignment | ||
Range on Protein: 32-137
Range on HMM: 177-279/293.0
STREISHYQFTSWKEKTTPNVA-LFVGFVVASREVSKKyeQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEEskTSVVDLFEVAKRLRQARCGIISSLQ
..|.. .|.|||| . |. . .. || . ||. .| .....|..|||| | | ||.|.||| ... || . .||.| . .||. |. .. . .
eerkvrqyhftsWpdhgvPektktlldfvrtvreaiek..taskrPivvhCsaGvGRtGtfialdrllqaiee..edyvdifgivaelReeRnllvqtek
HYNFIYQ
.| ||.|
qYifihq
|
|||||||||
subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 32-137 | 3.9e-20 | 67.1 | In-house | 135-236 (250) | alignment | ||
Range on Protein: 32-137
Range on HMM: 135-236/250.0
STREISHYQFTSWKEKTTPNVALFVgfVVASREVSKKYEQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEESKtsVVDLFEVAKRLRQARCGIISSLQH
. | . ...|..| .|. |.|| | . ..| .. .| ..|||||.|| | | .| |.|.| . ...| |||.|.| |.||. | . . ||.
derivrqlhfvvWPdkgvPevatav..LellkkvqasqqqagnaPvivqCsaGvgrsGafiaidavlerlkkek..vvdvfkvikvlrkdrphavesleq
YNFIYQ
| |.|.
yvfvye
|
|||||||||
subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 32-137 | 9.7e-20 | 65.8 | In-house | 168-270 (281) | alignment | ||
Range on Protein: 32-137
Range on HMM: 168-270/281.0
STREISHYQFTSWKEKTTPNVAlfVGFVVASREVSKKYEQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEeSKTSVVDLFEVAKRLRQARCGIISSLQH
|||... ..|.| .. |. . .. .|| | |....||...||| | | ||...||| |.. | .... .|. .| . ||..| .. ..
etreveqlaytaWPdhGvPatt..kellefrkevlkltekktkaplvihCsaGvGrtGtyialDrlvkave.aeleeldvkavvaelrkernlmvqtvvq
YNFIYQ
|.|.|.
yefvyk
|
|||||||||
subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 32-136 | 4.1e-18 | 60.7 | In-house | 183-284 (319) | alignment | ||
Range on Protein: 32-136
Range on HMM: 183-284/319.0
STREISHYQFTSWKEKTTPNVALFVGFVVAS-REVSKKYEqeKDAPVIVHCSDGQGFTGVFVALDIGVRSHEESKtsVVDLFEVAKRLRQARCGIISSLQ
|.| . | | .. |. . . .| | . .| . . |...|||| | | |||...||. . .| | ||.... . ||| | .. .|
dirkitqfhflGwpdvGvpdypsdlmrlvkkvrhltsken..hranivvhcsaGvGrtGvyivldvlldrmkeek..qvdvynfvrdlrqqrntlvqdlv
HYNFIY
| |||
qykfiy
|
|||||||||
subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 32-137 | 4.6e-18 | 60.2 | In-house | 171-272 (287) | alignment | ||
Range on Protein: 32-137
Range on HMM: 171-272/287.0
STREISHYQFTSWKEKTtpNVALFVGFVVASREVSKKYEQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEesKTSVVDLFEVAKRLRQARCGIISSLQH
..... ||.|.|... .|. . .. | |. .. .....|||||. | ...|.| ..... . . |.|.|.| |. |. . | . ..
dkqqvkqyqitnWdstg..kvtepqtillvieemyktqrkrgntsivvhCsdtvGrsamfcaaattinkck..teGviDvfqvlksqriqkpgsvqtveq
YNFIYQ
|.||..
ykfind
|
|||||||||
subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 32-136 | 5.3e-18 | 60.5 | In-house | 147-248 (284) | alignment | ||
Range on Protein: 32-136
Range on HMM: 147-248/284.0
STREISHYQFTSWKEKTTPNVALFVGFVVAS-REVSKKYEqeKDAPVIVHCSDGQGFTGVFVALDIGVRSHEESktSVVDLFEVAKRLRQARCGIISSLQ
|.| . | | .. |. . . .| | ...| . . |...|||| | | |||...||. . .| . ||.... . ||| | .. .|
dirkirqfhflgwpdvgvpdypsdlmrlvkkvrhltsken..hranivvhcsagvgrtgvyivldvlldrmkee..kqvdvynfvrdlrqqrntlvqdlv
HYNFIY
| |||
qykfiy
|
|||||||||
subfamily_PTPN12_pd | Subfamily PTPN12 | 32-137 | 3.8e-17 | 57.1 | In-house | 168-271 (290) | alignment | ||
Range on Protein: 32-137
Range on HMM: 168-271/290.0
STREISHYQFTSWKEKTTPNVALFvgfVVASREVSKKYEQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEESKT-SVVDLFEVAKRLRQARCGIISSLQ
.|.. ...|.| .. .|. | ... | .......|||..|||| | | ||. .|.|. . .. |. . .|.|.. .||. | .. . .
esrkvyqfhYtaWPDhgvPssaks...llelielvrelqesedaPlvvhCsaGvGrtGtiiaidyvrellkaekipeeldvfdlvlelrkqraalvqtke
HYNFIYQ
|...|.
qyelvyk
|
|||||||||
subfamily_Sponge-PTP9_pd | Subfamily Sponge-PTP9 | 32-137 | 6.7e-17 | 56.1 | In-house | 186-287 (301) | alignment | ||
Range on Protein: 32-137
Range on HMM: 186-287/301.0
STREISHYQFTSWKEKTT---PNVALFVgfvVasREVSKKYEQEKDAPVIVHCSDGQGFTGVFVALDIGVrshEESK-TSVVDLFEVAKRLRQARCGIIS
|.... .| |.| . |. | | . .| .. . .||.|||||. . .||.....||. | | |||.|.| |..|. . | .
sswdvlqlqvtdWpqdGvvreprtvLqv...i..ddvihrqqkigggpvvVHCSdtVsrsGvYcsvsigl...EQckaegVVdvfqvtkavrrskpgaVt
SLQHYNFIYQ
|. | .||.
TLeqytsiyd
|
|||||||||
subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 32-137 | 2.4e-15 | 51.4 | In-house | 131-233 (237) | alignment | ||
Range on Protein: 32-137
Range on HMM: 131-233/237.0
STREISHYQFTSWKEKTTPNVALFVgFVVASREVSKKYEQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEESKtsVVDLFEVAKRLRQARCGIISSLQH
| | |||||| .. |. . . . . . . . .| |.||| | | ||.|. .| .| .| | |||... . . . | || . ..
evrlihqyqftswpdrgvpqqtaal.lrfrkniinrsphvsesgpwiihcsagvgrtgiflvidamlrqakekk..vvdiynyvysieedrpyiiqtkdq
YNFIYQ
| ||.|
yvfihq
|
|||||||||
subfamily_Sponge-PTP6_pd | Subfamily Sponge-PTP6 | 32-136 | 6.3e-14 | 46.3 | In-house | 172-272 (439) | alignment | ||
Range on Protein: 32-136
Range on HMM: 172-272/439.0
STREISHYQFTSWKEKTTPNVALFVGFVVasREVSKKYEQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEesKTSVVDLFEVAKRLRQARCGIISSLQH
| . ......| .| | | .| . | . ..|. ||.|||| | | || .|||| . ||. . | ||. | .. .| .
kertvlqfhyiawpdknvpaqashvldfl..rainsandkeeygpvvvhcsagvGrtGtiialdialeqlk..lenkvdikgivkvlrkqrkqmvqalcq
YNFIY
| |||
yvfiy
|
|||||||||
subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 32-136 | 7.2e-11 | 36.6 | In-house | 154-252 (267) | alignment | ||
Range on Protein: 32-136
Range on HMM: 154-252/267.0
STREISHYQFTSWKEKTTPNVALFVGFVVasreVSKKYEQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEesKTSVVDLFEVAKRLRQARCGIISSLQH
|..... | . |. .| . | | . ..|. .. . |..|.|||| | .| |. .| .. . .|.|.|. ...|. | |.. ....
sahnvtlyyykkwnintnnkpylkplfgi....laknqlengnrPlvvacsdGvGrsGtflvidsqlerak..tegvsdifdflrkirsqriglvdtker
YNFIY
| .|.
yiyih
|
|||||||||
subfamily_Cele-PTP-19_pd | Subfamily Cele-PTP-19 | 32-132 | 3.4e-10 | 34.1 | In-house | 179-271 (301) | alignment | ||
Range on Protein: 32-132
Range on HMM: 179-271/301.0
STREISHYQFTSWKEKTTPNVALFVgfvVASREVSKKYEQekdaPVIVHCSDGQGFTGVFVALDIGVRSHEESKTsvVDLFEVAKRLRQAR-CGIISSLQ
.|| . |||...| .. .|. . |. || |. |..||||.| | . |.. .. | | .| ..| | |.||. | .|. |
atrtvthyqysewtdrgvPkshael...fdlmelvkksek....PivvhcsaGiGrsvafigteylareveadpt..ieltealkhlrehrwngvqtnsq
HY
|
ly
|
|||||||||
subfamily_Cele-PTP-9_pd | Subfamily Cele-PTP-9 | 32-127 | 1.7e-09 | 32.1 | In-house | 114-205 (255) | alignment | ||
Range on Protein: 32-127
Range on HMM: 114-205/255.0
STREISHYQFTSWKEKTTPNVALFVGFVVASREVSKkyeqekdaPVIVHCSDGQGFTGVFVALDIG----VRSHEESKTSVVDLFEVAKRLRQARCGIIS
|... ||... | || .|. | . ... || .|.|||| | | . || .. .|| ....| .| .. . ||. | . |
kthtvkhysykGWieknaPelareilnilkvvrdsk........svvvhCstGiGrsaafvlaelvyqkmirsldttetveldylslleelrskrkraih
|
|||||||||
subfamily_Cele-PTP-6_pd | Subfamily Cele-PTP-6 | 32-135 | 1.8e-09 | 32.0 | In-house | 174-269 (307) | alignment | ||
Range on Protein: 32-135
Range on HMM: 174-269/307.0
STREISHYQFTSWKEKTTPNVALFVGFVVASrevsKKYEQekdAPVIVHCSDGQGFTGVFVALDIgVRSHEESKTSVVDLFEVAKRLRQARCGIISSLQH
.| |.|.|.. | .. .|.. | .. . .|.. ||.|||| | | .| ||. . |. . |. .. . ||. | | .
ksrtiqhlqwenwpdrgvpqinltainllea....vrydt...npvvvhcsaGvGrsGtivaisl.vqdkmiaGinckdmkklveelrsqrhyaiqteaq
YNFI
| ..
ylyl
|
|||||||||
subfamily_ptpA1_pd | Subfamily ptpA1 | 32-96 | 6.9e-07 | 23.3 | In-house | 184-251 (418) | alignment | ||
Range on Protein: 32-96
Range on HMM: 184-251/418.0
STREISHYQFTSWKEKTTPNVALFVG---FVVASREVSKKYEQEKDAPVIVHCSDGQGFTGVFVALDI
||.|..||. | .. |. . . . .. |. ... |.||||| | | || |.. |
etrditqyqyegwpdhnipdhtqpfrqllhsitnrqnqiipssdrnvpiivhcsagvgrtgtfctavi
|
|||||||||
subfamily_hpo-7_pd | Subfamily hpo-7 | 32-127 | 1.9e-06 | 22.0 | In-house | 120-211 (263) | alignment | ||
Range on Protein: 32-127
Range on HMM: 120-211/263.0
STREISHYQFTSWKEKTTPNVALFVGFVVASREVSKkyeqekdaPVIVHCSDGQGFTGVFVALDIG----VRSHEESKTSVVDLFEVAKRLRQARCGIIS
|... ||... | || |. | . .. || ...|||| | | . |. .. .|| ....| .| .. . ||. | . |
kthtvkhysykgWiekndpelareilnilkvarnsk........slvvhcstGiGrsaafsvaElvyqkmirsldttstveldylsLleelrssrkraih
|
|||||||||
subfamily_PTPN5_RR_pd | Subfamily PTPN5_RR | 33-137 | 2.5e-22 | 74.3 | In-house | 160-262 (274) | alignment | ||
Range on Protein: 33-137
Range on HMM: 160-262/274.0
TREISHYQFTSWKEKTTPNVALFVGFVVASREVSKKYEQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEEskTSVVDLFEVAKRLRQARCGIISSLQHY
.|.. || .|.| .. .|. | . .|. | |.. |..| |||.|||| | | ||.|.| .|.|| .| ..|||.... ||. | |.. . . |
ersvkhywytdWPdhksPddantlldlvleveesreeenaklapvvvhCsaGiGrtGcfiaisiavrqlre..eivvdvlkivcnlrldrGGmvqtseqy
NFIYQ
..|..
elihr
|
|||||||||
subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 33-137 | 1.4e-20 | 68.6 | In-house | 174-273 (288) | alignment | ||
Range on Protein: 33-137
Range on HMM: 174-273/288.0
TREISHYQFTSWKEKTTPNVAL-FVGFVvasREVsKKYEQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEEskTSVVDLFEVAKRLRQARCGIISSLQH
.|| .||...| .. |. . ..... | | | .|.. |.|||||.| | ||.|.||| . || . ..|.... ..||. | .. |..
eleitqyqylaWpdhgvPeskapllell...rqv.kvanqadtgpiivhCsaGvGrtgtFialdalidavee..edyiDvagtvaklRkqRallvqtlkq
YNFIYQ
| |||.
Yefiye
|
|||||||||
subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 33-137 | 4.6e-19 | 63.5 | In-house | 174-273 (315) | alignment | ||
Range on Protein: 33-137
Range on HMM: 174-273/315.0
TREISHYQFTSWKEKTTPNVAlfVGFVVASREVsKKYEQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEESKtsVVDLFEVAKRLRQARCGIISSLQHY
||. ...||| . |. . . .. | | |...... ....||||.|.| || |..|| . | . ..|.... ...|| | ....... |
irevvqlhytswpdmgvpkyt..iplmnlirtv.kqhhtnsvgaivvhcsaGvGrtGtfitldavldqaeaen..aidvynfitgvrqnrikmvqvaeqy
NFIYQ
.|||.
qfiyd
|
|||||||||
subfamily_PTPN14_pd | Subfamily PTPN14 | 33-137 | 5.2e-19 | 63.4 | In-house | 182-290 (300) | alignment | ||
Range on Protein: 33-137
Range on HMM: 182-290/300.0
TREISHYQFTSWKEKTTPN-VALFVGFVVASREVSKKYEQEK-----DAPVIVHCSDGQGFTGVFVALDIGVRSHEESKtsVVDLFEVAKRLRQARCGII
|.. | |.| | .. |. | |. .. . | .| ..|. . ||.||||.| | ||| . |. . . | . ..|. .| .|||. | ..
ertvwhlqytDWpdhgvPeDvkgflsyLeevqsvrrktnseveskeskPPvlvhCsaGvGrtGvlilsdlliatlehne..eidikkvlarLreqrmllv
SSLQHYNFIYQ
..| |.|.|.
qtlaqYkfvYk
|
|||||||||
subfamily_Sponge-PTP5_pd | Subfamily Sponge-PTP5 | 33-136 | 2.3e-17 | 57.8 | In-house | 161-259 (283) | alignment | ||
Range on Protein: 33-136
Range on HMM: 161-259/283.0
TREISHYQFTSWkekTTPNVALFVGFVVASREVSKKYEQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHeeSKTSVVDLFEVAKRLRQARCGIISSLQHY
| ..|||. | . . . .| | . ..|..|..|||| | | |.||.|. | ||||.|.| | .|. | ... .|. |
tlllahyqvidW...leygeqaiinslvkfnkvislqteskkgPivvhCstgiGrtavfiaasasvkda..ltesvvdvfavvkimreqrmmavqtldqy
NFIY
...
klvh
|
|||||||||
subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 33-137 | 4.1e-17 | 57.0 | In-house | 172-271 (315) | alignment | ||
Range on Protein: 33-137
Range on HMM: 172-271/315.0
TREISHYQFTSWKEKTTPNVALfvGFVVASREVSKKyEQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHeeSKTSVVDLFEVAKRLRQARCGIISSLQHY
.| .. .||| | .| ... . .. .|| . ...|. ...|||| | | |||....| | .|..||.|.. | ||. | .. . ..|
srtvtqfqftewPdkGvdkqts..sllklikevkad.ngkkefsllvhcsaGvGrtGvvisidevvaqi..krtrsvdvfnfvknlrakrpylvqteeey
NFIYQ
|||.
afiyd
|
|||||||||
subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 33-137 | 2.7e-16 | 53.8 | In-house | 171-270 (515) | alignment | ||
Range on Protein: 33-137
Range on HMM: 171-270/515.0
TREISHYQFTSWKEKTTPNVAlfVGFVVASREVSKKYEQEKdAPVIVHCSDGQGFTGVFVALDIGVRSHeeSKTSVVDLFEVAKRLRQARCGIISSLQHY
.| . ..|| | .| .|. . .. .|| . .| . |.|.||| | | |||....| | .| .||.|.. . .|| | .. ..|
srtvtqfhfteWPdkGvpkht..ssllklikevkadhgqyt.hpliihcsaGvGrtGvvisidsvvaha..kttrmvdvfnfvtnirqkrpylvqtqeqy
NFIYQ
|||.
afiyg
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 33-136 | 2.8e-12 | 40.7 | In-house | 88-187 (440) | alignment | ||
Range on Protein: 33-136
Range on HMM: 88-187/440.0
TREISHYQFTSWKEKTTPNVALFVGFVVasREVSKKYEQEKDAPVIVHCSDGQGFTGVFVALDIGVRshEESKTSVVDLFEVAKRLRQARCGIISSLQHY
.| . .|.. .| .| |..| | .. ..|.. |. ..|..|||| | | ||| .|.| .| | .. .|.| . . .|. | .. . ..|
srtlkqyhyqgwpdkgvpkfagpvlkmi..qdvnesqekagngpllvhcsagagrtgviiavdsilr..eakrsdqidifsfinsmrnnrpqmvqtpeqy
NFIY
|..
afvh
|
|||||||||
subfamily_Cele-PTP-13_pd | Subfamily Cele-PTP-13 | 33-136 | 2.9e-07 | 24.4 | In-house | 166-262 (281) | alignment | ||
Range on Protein: 33-136
Range on HMM: 166-262/281.0
TREISHYQFTSWKEKTTPNVALFVGfvvasrEVSKKYEqEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEeSKTSVVDLFEVAKRLRQ-ARCGIISSLQH
|| |.|. . | . |. . . .. .| . .| ..||| | | .| ..|..| ..| |. .. |. .. .|| |. . .||.
trlithwlwkewpdwqvpessevml......kilrkir.arstppvihcsagvgrsgtlmaveialqsih.shftlpdikqivshlrvtgraasvqtlqq
YNFIY
| .|.
ymliw
|
|||||||||
subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 34-136 | 4.8e-13 | 43.8 | In-house | 137-234 (239) | alignment | ||
Range on Protein: 34-136
Range on HMM: 137-234/239.0
REISHYQFTSWKEKTTPNVALFVgfVVASREVSKkYEQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEESKTsvVDLFEVAKRLRQARCGIISSLQHYN
| . .|.|| | .| |. | | . |...| | ..||| | | || |. .| .| .. || ||.|. | .|. | .. . ..|
ryvyqyhftvwpdkgvpqyatav..lglrrkitk.dslpgarpwvihcsagvgrtgaflvidamlrqakkqkt..vdifnyvkairedrphmvqtseqyv
FIY
||.
fih
|
|||||||||
subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 34-136 | 4.8e-13 | 43.8 | In-house | 136-233 (239) | alignment | ||
Range on Protein: 34-136
Range on HMM: 136-233/239.0
REISHYQFTSWKEKTTPNVALFVgfVVASREVSKkYEQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEESKTsvVDLFEVAKRLRQARCGIISSLQHYN
| . .|.|| | .| |. | | . |...| | ..||| | | || |. .| .| .. || ||.|. | .|. | .. . ..|
ryvyqyhftvwpdkgvpqyatav..lglrrkitk.dslpgarpwvihcsagvgrtgaflvidamlrqakkqkt..vdifnyvkairedrphmvqtseqyv
FIY
||.
fih
|
|||||||||
subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 34-127 | 1.2e-10 | 35.6 | In-house | 183-267 (290) | alignment | ||
Range on Protein: 34-127
Range on HMM: 183-267/290.0
REISHYQFTSWKEKTTPNVALFVGFVVasREVskkyeQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEESKTsvVDLFEVAKRLRQARCGIIS
. |.. || .|. .. .| . .. | . .. ||.|||| | | || |||...|.. . | .|| .. . ||..| . .
hklkhlkikswpdksvalstlallrtl..ril.....rkasGpvvvhcsaGiGrtGtfvaievglqilldGke..ldlldlvralrnsrlnsvq
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subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 34-136 | 1.4e-10 | 35.4 | In-house | 168-270 (287) | alignment | ||
Range on Protein: 34-136
Range on HMM: 168-270/287.0
REISHYQFTSWKEKTTPNV-ALFVGFVVAS-REVSKKYEQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEEskTSVVDLFEVAKRLRQARCGIISSLQH
| . ... || .|. . .. ||. . . . . .. |..||.. | | .|...|. . |. |. . || | |||. | ... .
rvvkqldllswPdkvlaPtavglirfvldvkqhielardasevGPlvvhddvGiGrsGillatlvlvsrled..lGrvdvaavvirlreyraalvqavvq
YNFIY
. ..|
lrlly
|
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subfamily_Cele-PTP-10_pd | Subfamily Cele-PTP-10 | 34-136 | 6.9e-08 | 26.5 | In-house | 188-282 (305) | alignment | ||
Range on Protein: 34-136
Range on HMM: 188-282/305.0
REISHYQFTSWKEKTTPNVALfvgfvvASREVSKKYEQEKdAPVIVHCSDGQGFTGVFVALDIGVRSHEESKTsVVDLFEVAKRLRQARCGIISSLQHYN
. | |.| | .. | . | .| |. | |..|||| | | || ||.. . | | . . |. | ||. |. | . .|
msvrhlqwtewpdrgvppckl......tslellsairgsk.vpivvhcsagigrtgtivaieyilekiaenkp.cppmpelvkalrdqrafsiqndvqyl
FIY
||.
fih
|
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subfamily_Cele-PTP-1_pd | Subfamily Cele-PTP-1 | 35-135 | 2.8e-10 | 34.8 | In-house | 159-251 (290) | alignment | ||
Range on Protein: 35-135
Range on HMM: 159-251/290.0
EISHYQFTSWKEKTTPNVALFVGFVVasrevsKKYEqEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEESKTSVvDLFEVAKRLRQARCGIISSLQHYNF
. |... .|.. ... . . .. .| . ...|||||| || .. |...| |.. || | .| | ||. | |.| . . |
tvtHsllkgWnklnvqedtktllsli......qkvk.asktpvivHcvdGiSrsAalaaiilgyQkiaetsgsv.kledvlkalrkqralaitsalelaf
I
.
v
|
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subfamily_Cele-PTP-11_pd | Subfamily Cele-PTP-11 | 35-119 | 2.9e-07 | 24.5 | In-house | 177-255 (312) | alignment | ||
Range on Protein: 35-119
Range on HMM: 177-255/312.0
EISHYQFTSWKEKTTPNVAlfvgfVVASREVSKKYEQEKdaPVIVHCSDGQGFTGVFVALDIGVRSH-EESKTSVVDLFEVAKRLR
. |||..|| .. |. | | .| . | ||| ||| | | || .. .. . . | | | | . .. |
klnhyqwaswpdhgmpdsc.....dtalrllsavkkdkk..pviahcsagvgrtgtlaliesmiaalrhprkqnvkdsfvllrkdr
|
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PTPc_DSPc_SM00012 | 36-137 | 3.7e-23 | 77.1 | In-house | 2-101 (105) | alignment | |||
Range on Protein: 36-137
Range on HMM: 2-101/105.0
ISHYQFTSWKEKTTPNVAlfVGFVVASREVSKKYEQEK-DAPVIVHCSDGQGFTGVFVALDIGVRSHEESKtSVVDLFEVAKRLRQARCGIISSLQHYNF
..||..|.|... .|. . .. . |.| |...... .||.||||.| | ||.|||||| ....|... . ||.|.. |.||. | | ..... | |
vkhyhytgwpdhgvPees..dsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleket.kevdifqivkelrkqRpgmvqteeqylf
IYQ
.|.
lyr
|
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subfamily_PTEN_pd | Subfamily PTEN | 36-132 | 1.9e-06 | 23.0 | In-house | 82-171 (184) | alignment | ||
Range on Protein: 36-132
Range on HMM: 82-171/184.0
ISHYQFTswkEKTTPNVALFVGFVvasREVSKKYEQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEESKTSVVDLFEvAKRLRQARCGIISSLQHY
...|.|. ....|.. |. .| ....| |..|. |.||| |.| ||| .. . . . |.......||. ..| ..... | | . |
vavypfd...Dhnppplelleeiv...ediekwleedkknvvvvHCkaGkGRtGvlivayllkslllekaeealelfa.eaRtknkkgvtiPsqrRY
|
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subfamily_Cele-PTP-4_pd | Subfamily Cele-PTP-4 | 39-136 | 1.9e-08 | 28.1 | In-house | 186-278 (302) | alignment | ||
Range on Protein: 39-136
Range on HMM: 186-278/302.0
YQFTSWKEKTTPnvALFVGFVVASREVsKKYEQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEESktSVVDLFEVAKRLRQARCGIISSLQHYNFIY
| .| ||.|. | . . . .| . ... |..... | | |.|..| . | . ... . . |..| .|. |. .. ||. |...|
yvltnWkqkkvp..vkyaeliktaakv.fakkikadentvivSknGaGRagafltlavaveklqkg..kepnikeivksiRsqRpravdslkQyvsly
|
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subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 63-136 | 1.3e-08 | 29.0 | In-house | 250-337 (350) | alignment | ||
Range on Protein: 63-136
Range on HMM: 250-337/350.0
REVS-KKYEQEKDAPVIVHCSDGQGFTGVFVALDIGVRS------------HEESKTSVVDLFE-VAKRLRQARCGIISSLQHYNFIY
.. . ..... .|..|||| | | ||..|.|| . . . . . || . . ..||. | .. .|. . |||
dlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaaktrDlisiivnelrkqrismvqnldqfifiY
|
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subfamily_CG42327_pd | Subfamily CG42327 | 65-137 | 8e-17 | 55.9 | In-house | 238-309 (319) | alignment | ||
Range on Protein: 65-137
Range on HMM: 238-309/319.0
VSKKYEQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEESKTSvVDLFEVAKRLRQARCGIISSLQHYNFIYQ
|. ..|. |..|||||| | ||. .| || .|| |||| | ||. .. .|. |. . . . |.|||.
ssrsgtresqGPlvvhcsdGvGrtGlviasdiairsleeskrs.vdiPqlvssvrrdrasavltkeqyefiyk
|
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subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 66-137 | 1.7e-08 | 28.7 | In-house | 220-289 (297) | alignment | ||
Range on Protein: 66-137
Range on HMM: 220-289/297.0
SKKYEQEKDAPVIVHCSDGQGFTGVFVALDIGVrsHEESKTSVVDLFEVAKRLRQARCGIISSLQHYNFIYQ
| . |. ..|...|||| | | .|| | |. . | . | . . ||. | .. .|. ....|.
slraemprnayllvhcsaGvGrsGvvvlsdvil..aklrkkripdvaailsilreqrarlvqtleqfellyd
|
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subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 66-110 | 4.1e-07 | 23.6 | In-house | 257-301 (349) | alignment | ||
Range on Protein: 66-110
Range on HMM: 257-301/349.0
SKKYEQEKDAPVIVHCSDGQGFTGVFVALDIGVRSHEESKTSVVD
. ..... ....|||| | | |||.| ||. . | . .
rlyldtdqlstllvhcsaGcGrtGvlvtldlllsileplqnesnk
|
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subfamily_Sponge-PTP-7_pd | Subfamily Sponge-PTP-7 | 78-136 | 9.2e-07 | 23.2 | In-house | 2-58 (69) | alignment | ||
Range on Protein: 78-136
Range on HMM: 2-58/69.0
IVHCSDGQGFTGVFVALDIGVRSHEESKtsVVDLFEVAKRLRQARCGIISSLQHYNFIY
.|||| | | || |.|. . . | .||.|. . .|. | .. . | ||.
vvhcssgtgrtgtfiaimvemariksek..lvdifnnvqymrkcrpmmvmneieyifih
|
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subfamily_Sponge-PTP7_pd | Subfamily Sponge-PTP7 | 78-136 | 1.6e-06 | 22.4 | In-house | 1-57 (69) | alignment | ||
Range on Protein: 78-136
Range on HMM: 1-57/69.0
IVHCSDGQGFTGVFVALDIGVRSHEESKtsVVDLFEVAKRLRQARCGIISSLQHYNFIY
.|||| | | || |.|. . . | .||.|. . .|. | .. | ||.
vvhcssGtGrtGtfiaimvemariksek..lvdifnnvqymrkcrpmmvmneneymfih
|