Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
---|---|---|---|---|---|---|---|---|---|
subfamily_PTPRB_pd | Subfamily PTPRB | 1-256 | 3e-97 | 320.2 | In-house | 31-283 (293) | alignment | ||
Range on Protein: 1-256
Range on HMM: 31-283/293.0
FQSLSHLGPRATFEAAQTPYNKTKNRYPNILPYDHSRVVLRARKDSHGSDYINANFVDGYGCPQKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTEH
...|...| . .||... |..|||| |||||||||| | | ||..||||||||...|| .|...||.|||| ||..||||..||| ...|||| ..
yeelkavgkdqavkaaelavnraknrytnilpydhsrvkLaalkdesgsDYinanyipgynsprefiatqGPlpetvddfWrmvwekkssiivmltqlve
KLRSDCERYWPED-GHQEYGDVAVSVVDVTHMTDWTVRTFLVWVrlhpeCMDKREVTQFQFTAWPDQGVPENTAPLIIFHHKYRYHL-SSEETGPILVHC
| . ||.|||.| . |||. |..| ....||..|.... ...|.|.|..||.||| ||||.|..|. | .. | .. ......||.|||
kgkvkCeeYWPadeepvlyGdikvtlvaeeeledwvirelkiek.....ekeerkvrqyhftsWpdhgvPektktlldfvrtvreaiektaskrPivvhC
GAGVGRTGTFIAIDSLMDQMMMEGVVDVYGFVAQMRTQRNFMVQTHEQYAFIYDVLRD
|||||||||||.| |.... | .||..|.||..|..||..||| .|| ||.... |
saGvGRtGtfialdrllqaieeedyvdifgivaelReeRnllvqtekqYifihqcvld
|
|||||||||
0050432 | (Phosphotyrosine protein) phosphatases II | 1-260 | 1.3e-94 | 312.3 | In-house | 48-301 (308) | alignment | ||
Range on Protein: 1-260
Range on HMM: 48-301/308.0
FQSLSHLGPRATFEAAQTPYNKTKNRYPNILPYDHSRVVLrarkdSHGSDYINANFVDGY--GCPQKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDT
|. | .. | ....|. | ||.||||..|||||||||.| ..|||||||..|||| ..|.|.||.|||| .|..||||..|| ....|||| ..
feellsvkplleysvallpenkdkNrykdilpydhsRVkl.....degsdYInAsyvdgyssklprkfIatqgPlpntvedFwrmvweqnvrvIvmLtkl
EHKLRSDCERYWPED---GHQEYGDVAVSVVDVTHMTDWTVRTFLVWVRLHPecmDKREVTQFQFTAWPDQGVPENTAPLIIFHHKYRYHLsseETGPIL
. . | |..|||.. | .|||.. | ....... |.||||. .. . . |.||.|..|.|||.|||.....|. | .. | .| . |||.
vengrekcaqYwplelgggsleygkftvtllseevlddytvrtleltnlgdg...esrtvthfhytnWpdhgvPpspeilldflelvrksl...pggpiv
VHCGAGVGRTGTFIAIDSLMDQMMMEGVVDVYGFVAQMRTQRNFMVQTHEQYAFIYDVLRDASLC
||| |||||||||||.| |..|. .|| |||.. |...|.||..|||| ||| |.|..| . ..
VHCsaGvGRtGtfialdllleqlekeggvdvfeavkklReqRpgmvqtpeqylflyralleylkl
|
|||||||||
0051299 | (Phosphotyrosine protein) phosphatases II | 1-256 | 2.2e-94 | 311.4 | In-house | 29-284 (288) | alignment | ||
Range on Protein: 1-256
Range on HMM: 29-284/288.0
FQSLSHLGPRATFEAAQTPYNKTKNRYPNILPYDHSRVVLRARKDSHGSDYINANFVDGYGCPQKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTEH
|. | .| | |. ||. | |..||||..|||||||||.|. ....|||||||...||| ...|.||.|||| .|..||||..||.....|||| ...
feellsllpdltlsaallpenleknRysdilpydhsRVkLsvldgvegsdYinAsyidgynlkrkfIatqgPlpntvedFWrmvweqnvrvIvmltklve
KLRSDCERYWPEDGHQEYGDVAVSVVDVTHMTDWTVRTFLVWVR-LHPECMDKREVTQFQFTAWPDQGVPENTAPLIIFHHKYRYHLSsEETGPILVHCG
. | .|..|||..|...|||. | ...... |.||||. | |. . .|.||.|..|.|||.|||... .|. | .. | .|. ||..|||
lgrekcaqYwplggsltygditvtllseevlddytvrtlevtnldlldgdgesrtvthfhytnwpdhgvpdspellldflrlvrkala.sgggpvvVHCs
AGVGRTGTFIAIDSLMDQMMMEGVVDVYGFVAQMRTQRNFMVQTHEQYAFIYDVLRD
|||||||||||.| |..|. ||.|||...|...|.||..|||| ||| |.|..| .
aGvgRtgtfialdllleqlekeggvdvleavkrlreqRpgmvqtpeqyrfvyealle
|
|||||||||
subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 1-255 | 7.6e-91 | 299.1 | In-house | 27-276 (288) | alignment | ||
Range on Protein: 1-255
Range on HMM: 27-276/288.0
FQSLSHLGPRATFEAAQTPYNKTKNRYPNILPYDHSRVVLRARKDSHGSDYINANFVDGYGCPQKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTEH
..||. |. . .|.. . |..||||.||||||. || |. .. .|.|||||...||.. .||||.||||..|..|||.|..|. .||||| .
ynsLaalektksvtagrlavnakknRyrnilpyDekrvklkkleeeagaDYinasyidgekkkkkyiatqgPladtvndfWelvyenktstivmltelve
KLRSDCERYWPEDGH-QEYGDVAVSVVDVTHMTDWTVRTFLVWvrlhpECMDKREVTQFQFTAWPDQGVPENTAPLIIFHHKYRYHlSSEETGPILVHCG
. .. ||.|||.... ..||.| | .|.. ...|...|..|. ....|.||.|..||||.||||..|||. . .. ....||||.|||
ggktkCeeYWPdadkpknyGsvtvtlveskeledfvlrkllle.....kkkteleitqyqylaWpdhgvPeskapllellrqvkva.nqadtgpiivhCs
AGVGRTGTFIAIDSLMDQMMMEGVVDVYGFVAQMRTQRNFMVQTHEQYAFIYDVLR
|||||||||||.| |.|.. | ..|| |.||..| ||...||| .|| |||.||
aGvGrtgtFialdalidaveeedyiDvagtvaklRkqRallvqtlkqYefiyevll
|
|||||||||
0047943 | (Phosphotyrosine protein) phosphatases II | 1-255 | 8.2e-90 | 296.2 | In-house | 18-269 (273) | alignment | ||
Range on Protein: 1-255
Range on HMM: 18-269/273.0
FQSLSHLGPRATFEAAQTPYNKTKNRYPNILPYDHSRVVLrarkDSHGSDYINANFVDGYGCPQKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTEH
|. | | | |...|. | ||.||||..|||||||||.| .. |||||||..|||| ...|.||.|||| .|..||||..||.....|||| ...
felllslkplltysvallpenkdknrykdilpydhsrvkl....gdggsdyinAsyvdgynlkrkfiatqgPlpntvedfwrmvweqnvrviVmLtelve
KLRSDCERYWPEDG---HQEYGDVAVSVVDVTHMTDWTVRTFLVWVRLHPEcmdKREVTQFQFTAWPDQGVPENTAPLIIFHHKYRYHLSSE-ETGPILV
. | .|..|||..| ...||.. | ...... |.||||. .. .| .|.||.|..| |||.|||.....|. | .. | .|.. . ||..|
lgrekcaqYwpleggelsltygkftvtllseetkddytvrtleltnlgtge...srtvthfhytgwpdhgvppslesllefielvrkalealpsngpvvV
HCGAGVGRTGTFIAIDSLMDQMMMEGVVDVYGFVAQMRTQRNFMVQTHEQYAFIYDVLR
|| |||||||||||.| |.||. .|| |||. |...|.|| |||| ||| |.|..|
HCsaGvgRtgtfialdllldqlekeggvdvleavkllrsqRpgmvqtpeqyrflyeall
|
|||||||||
subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 1-257 | 7.9e-82 | 269.5 | In-house | 21-275 (281) | alignment | ||
Range on Protein: 1-257
Range on HMM: 21-275/281.0
FQSLSHLGPRATFEAAQTPYNKTKNRYPNILPYDHSRVVLRARKDSHGSDYINANFVDGYGCPQKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTEH
...|...| . | .|.... |..|||| || ||..||.. .... .||||||||.|| ...|||.|||. .....||...||. ..|||. .
yeklaaigvdntataskadenvlknrYsnivaYDatrvkvtpneenkntDYinanfvpgykgekeyiatqgPvPaslvafWqmvweqkvsaivmvtreie
KLRSDCERYWPEDG-HQEYGDVAVSVVDVTHMTDWTVRTFLVwvrlHPECMDKREVTQFQFTAWPDQGVPENTAPLIIFHHKYRYHLSSEETGPILVHCG
. . | ||||.| . .|||| |. . .. . . |.| . . | ..|||.|...|||||.|||..|. |. |... . .... |...||
agklkChrYWPddnselkygdvtvkstaeeekatyierkfkl....eresgetreveqlaytaWPdhGvPattkellefrkevlkltekktkaplvihCs
AGVGRTGTFIAIDSLMDQM-MMEGVVDVYGFVAQMRTQRNFMVQTHEQYAFIYDVLRDA
||||||||.||.| |.... .. .|| ||..| .||.|||| ||.|.| .. ||
aGvGrtGtyialDrlvkaveaeleeldvkavvaelrkernlmvqtvvqyefvykavlda
|
|||||||||
subfamily_PTPN13_pd | Subfamily PTPN13 | 1-254 | 7.3e-64 | 210.7 | In-house | 17-265 (273) | alignment | ||
Range on Protein: 1-254
Range on HMM: 17-265/273.0
FQSLSHLGPRATFEAAQTPYNKTKNRYPNILPYDHSRVVLRARKDshgsdYINANFVDGYGCP--QKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDT
|. | .| | | | ... ||.|||| |.||||..|| | . ||||... .|||.|||| ||.||||...||. .. |.|.
fkelrelkpldtcevgkkkenkdknryrnvlPydetrvklgdegg.....yinaslikvpvgkdeyeyiacqGPlPetvkdfwqmvweqkaeviamvtle
EHKLRSDCERYWPEDGHQE---YGDVAVSVVDVTHMTDWTVRTFLVwvrLHPECMDKREVTQFQFTAWPDQGVPENTAPLIIFHHKYRyHLSSeETGPIL
| . |.||||| ... .. . |....|... ...||.. | . | . |||....|..||| ||| ..|.|. | . | .| . ..|||.
kekgkvkchrywPesknkklkvsnrlevellkvqkldgfvvralav...kdsesgesrevahlnfvkwPdhgvPssaaellqfvaevr.rlqt.dagPiv
VHCGAGVGRTGTFIAIDSLMDQMMMEGVVDVYGFVAQMRTQRNFMVQTHEQYAFIYDVL
||| ||.||.||.|.|| ... . . .|| | ..| ||. .|||..|| |.| ..
vhcsaGiGrsGtlitidvvlglierdkefdvkeivrklreqrqgvvqtkdqyifvykai
|
|||||||||
subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 2-283 | 2.9e-96 | 317.3 | In-house | 30-308 (319) | alignment | ||
Range on Protein: 2-283
Range on HMM: 30-308/319.0
QSLSHLGPRaTFEAAQTPYNKTKNRYPNILPYDHSRVVLRARKDSHGSDYINANFVDGYGCPQKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTEHK
. |.. .. ||. |... ||.||||.|||.||..|||| . ....|||||||.|.||| .|.||.|.|| .||.||||..||... ..||| . |
kllkeavnd.tfdsaskeenkkknryqnilaydrtrvvlseldgvegsdyinasfidgyqerekfiatqaPlentiedfWrmvWeeessivvmltklvek
LRSDCERYWPEDGHQEYGDVAVSVVDVTHMTDWTVRTFLVwvRLHPECMDKREVTQFQFTAWPDQGVPENTAPLIIFHHKYRYHLSSEETGPILVHCGAG
|. ...|||| ..||| . | . . .. |. .| . . . . . .. |||..||.|.|||..|||.. |. . .. | . .. ||| ||| ||
lkvklkkywpeenfeeyGrlivtleeeeeledyiirklkl..nkkssevetRevkhfqyteWpdhdvPekatslldllkrirksrektqsgPivvhCsaG
VGRTGTFIAIDSLMDQMMMEGVVDVYGFVAQMRTQRNFMVQTHEQYAFIYDVLRDASLCGITEIPSQEIASSLLVLRDNDPD
||||||||..| .... |||.||. .| ..|||||.|||..||| |||..|..| .| ||| |.. | |.....|
vGRtGtfivldamlervkeegvlDvfstvsrlRtqRnimvqrpeqYkfiyealleaveagdteievqdlrdrlkqlaekvad
|
|||||||||
0036941 | (Phosphotyrosine protein) phosphatases II | 2-269 | 1.5e-90 | 298.8 | In-house | 20-288 (297) | alignment | ||
Range on Protein: 2-269
Range on HMM: 20-288/297.0
QSLSHLGPRATFEAAQTPYNKTKNRYPNILPYDHSRVVLrarkDSHGSDYINANFVDGYGCPQKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTEHK
..| .| . ....|. | |..||||..||||||.||.| |. |||||||..||||....|.||.|||| .|. ||||..|| ..|.|||| . . .
eellpllllgslsvallpenleknRykdilpydhtRVkl....ddegsdYinAsyvdgydlkrkfIatqgPlpntvedFWrmvweqnvtvIvmltelvel
LRSDCERYWPED--GHQEYGDVAVSVVDVTH--MTDWTVRTFLVWVRlhpECMDKREVTQFQFTAWPDQGVPENTAPLIIFHHKYRYHLSSE-ETGPILV
| |..|||.. . ..|||. | ...|.. .|.|.||. |. .. ..|.||.|..| ||| ||||..|.|. | .. | .|. . ||.||
grekcaqywpleegesltygdftvtllsvevvllddytlrtlevtdt...gngesrtvthfhytgwpdhgvpespaslldfielvrkvlkllpsggpvlV
HCGAGVGRTGTFIAIDSLMDQMM---MEGVVDVYGFVAQMRTQRNFMVQTHEQYAFIYDVLRDASLCGITEIPSQE
|| |||||.|||||.| ...|. .|| ||.. .| ..|.||...||| ||| |.|..| . ... | .| ..
HCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyeallellkkkltkepllk
|
|||||||||
DSPc_SM00195 | 2-255 | 4.2e-86 | 283.9 | In-house | 7-259 (263) | alignment | |||
Range on Protein: 2-255
Range on HMM: 7-259/263.0
QSLSHLGPRATFEAAQTPYNKTKNRYPNILPYDHSRVVLRARKDSHGSDYINANFVDGYGCPQKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTEHK
..| . ... |. . ||.|||| |||||||.|| | .... ||||||||...|. ...||||.|||| .|..||||..||.....|||| . | .
ekleestspketteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivmlteeeen
LRSDCERYWPED--GHQEYGDVAVSVVDVTHMT-DWTVRTFLVWVRLHpecMDKREVTQFQFTAWPDQGVPENTAPLIIFHHKYRYHLSSEeTGPILVHC
. |.|||||. | ...|.. | .|.|... ....||. . . ..|.|||.|...|||.|||..| ... . .. . . |.. .|||.|||
gkekcdrywpeesggketfgkisvklvevekkkdeiilrtleltkegk...eetrkvtqyqyknWpdhgvpdstksvlellravkksksts.sgpivVhC
GAGVGRTGTFIAIDSLMDQMMMEGVVDVYGFVAQMRTQRNFMVQTHEQYAFIYDVLR
|||||||||..||...... .| ||. | ..|.|| ||||.|||.|||...
saGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeail
|
|||||||||
PTPc_SM00194 | 2-255 | 4.2e-86 | 283.9 | In-house | 7-259 (263) | alignment | |||
Range on Protein: 2-255
Range on HMM: 7-259/263.0
QSLSHLGPRATFEAAQTPYNKTKNRYPNILPYDHSRVVLRARKDSHGSDYINANFVDGYGCPQKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTEHK
..| . ... |. . ||.|||| |||||||.|| | .... ||||||||...|. ...||||.|||| .|..||||..||.....|||| . | .
ekleestspketteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivmlteeeen
LRSDCERYWPED--GHQEYGDVAVSVVDVTHMT-DWTVRTFLVWVRLHpecMDKREVTQFQFTAWPDQGVPENTAPLIIFHHKYRYHLSSEeTGPILVHC
. |.|||||. | ...|.. | .|.|... ....||. . . ..|.|||.|...|||.|||..| ... . .. . . |.. .|||.|||
gkekcdrywpeesggketfgkisvklvevekkkdeiilrtleltkegk...eetrkvtqyqyknWpdhgvpdstksvlellravkksksts.sgpivVhC
GAGVGRTGTFIAIDSLMDQMMMEGVVDVYGFVAQMRTQRNFMVQTHEQYAFIYDVLR
|||||||||..||...... .| ||. | ..|.|| ||||.|||.|||...
saGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeail
|
|||||||||
subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 2-254 | 9.9e-68 | 223.1 | In-house | 27-279 (290) | alignment | ||
Range on Protein: 2-254
Range on HMM: 27-279/290.0
QSLSHLGPRATFEAAQTPYNKTKNRYPNILPYDHSRVVLRARKDSH--GSDYINANFVDGYGCPQKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTE
..| | . . |. ||..||. ||..|| |..|| . . .|||| ...|| ..|||.|||...|..|||.|||.. .| |||| .
kmldsgesehtvtvgltssnkllnRfanivvyddnritLrpisghkDCtneyinAcyikgykekkqyiatqgpvsntlvdFWkliwqekvtiivmltnii
HKLRSDCERYWPEDGHQEYGDVAVSVVDVTHMTDWTVRTFLVWVRLHPecMDKREVTQFQFTAWPDQG-VPENTAPLIIFHHKYRYHLSSEeTGPILVHC
. . | |||. . ..|| . . ... ..... . |.. | . .|..|||.|.|.|...| |..... |..... |. . . ..|.|||
eegkvkCqqYWpdsdtkaygefsikllneetlneyierklevknknsa..gakqsvtqyqitnwdstgkvtnpqtillvieemyktqrkrg.ntsivvHC
GAGVGRTGTFIAIDSLMDQMMMEGVVDVYGFVAQMRTQRNFMVQTHEQYAFIYDVL
..|||...|.|.. .... .|||.||. . ..|.|. .||| .|| .|....
SdtvgrsavfcaaattinkcktegvidvfqvlksqRiqkpgsvqtvqqyqgifqiv
|
|||||||||
0043336 | (Phosphotyrosine protein) phosphatases II | 3-255 | 1.2e-86 | 285.9 | In-house | 28-274 (278) | alignment | ||
Range on Protein: 3-255
Range on HMM: 28-274/278.0
SLSHLGPrATFEAAQTPYNKTKNRYPNILPYDHSRVVLRARKDSHGSDYINANFVDGYGCPQKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTEHKL
.| . . |.. |. | ||.||||..|||||||||.| . .||||||..|||| .|.|.||.||||.||..||||..|| |.|||||| . . .
ellsfkl.dtysiallpenkdknrykdilpydhsrvklsllggdldsdYinAsyvdgynvprkfiatqgPlpetvedFwrmvwelgvttivmLtelvelg
RSDCERYWPeDGHQEYGDVAVSVVDVTHMTDWTVRTFLVWVRLHPECmdkREVTQFQFTAWPDQGVPENTAPLIIFHHKYRYHLSsEETGPILVHCGAGV
| | .||| .|...|||. | .....|. |.||||. |. . ..|. |.||......|||.||||....|. | .. | .|. . ||.|||| |||
rvkcaqYwp.ggsltygdftvtllkeehlddytvrtlevtnlgdges...rtvthyhylgwpdhgvpeslsllldflkavreale.dsngpvlVHCsaGv
GRTGTFIAIDSLMDQMMMEGVVDVYGFVAQMRTQRNFMVQTHEQYAFIYDVLR
||||||||.. |..|.. || ||.. |...|.|| .||| .|| |.|..|.
gRTGtfialyllleqlekeggvdleeavkelreqRpgavqtpsqyrflyeall
|
|||||||||
subfamily_PTPN3_pd | Subfamily PTPN3 | 4-254 | 4.3e-65 | 214.4 | In-house | 24-271 (280) | alignment | ||
Range on Protein: 4-254
Range on HMM: 24-271/280.0
LSHLGPRATFEAAQTPYNKTKNRYPNILPYDHSRVVLRARKdshGsDYINANFVD----GYGCPQKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTE
| | . .||. | | .|||| .|||||. || |.. . ||||||.|. . | ..|||.||||..| .|||...||. ...|||| ..
lyrkkpglaisaarkpenlsknryrdilpydatrvklkese...t.dyinanyvnmeipstglvnryiatqGPlaktatdfWqmvweqksslivmlttlv
HKLRSDCERYWPEDG-HQEYGDVAVSVVDVTHMTDWTVRTFLVWVRlhpECMDKREVTQFQFTAWPDQGVPENTAPLIIFHHKYRYHLSsEETGPILVHC
. | | .|||| . ..|||. | . . . . .| ... . | ..|...|.|..||||.|||...| .. | .. | | .. |..|||
erGrvkChqyWPetedeleygefsvkcekedetksyvlrelvlkdk...etkeerkilqlqylaWpdhgvPddsadflefvervrklrs.gkeePvvvhC
GAGVGRTGTFIAIDSLMDQMMMEGVVDVYGFVAQMRTQRNFMVQTHEQYAFIYDVL
||.|||| .|... . . .. | . | .|| || .|||..|| |. . .
saGigrtGvlilletalalieaaepvypldivrtmrdqramlvqtasqykfvCeai
|
|||||||||
subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 6-266 | 4.5e-81 | 267.6 | In-house | 45-299 (319) | alignment | ||
Range on Protein: 6-266
Range on HMM: 45-299/319.0
HLGP-RATFEAAQTPYNKTKNRYPNILPYDHSRVVLRARKDSHGSDYINANFVDGYGCPQKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGdtehklRS
.||. |. . | . || |||. |||..|...| |. .|||||| ||.|| ..||||||||| .|..||||.||| |.|||.| .
klgvnladqtfanldqnkdknriinilafdknvvklerliGeefsdyinasfvtGyqrkdkyiaaqGPldntladfWrmiweyncstivllt......kd
DCERYWPEDGHQEYGDVAVSVVDVTHMTDWTVRTFLVWVrlHPECMDKREVTQFQFTAWPDQGVPENTAPLIIFHHKYRyHLSSE--ETGPILVHCGAGV
| .||| .. .... |.| |. ...|| . . . . |.|..||| | |||.|||. ...|. . .| | || | . .|.||| |||
kcsqywplkivikeerfkvkvdsveetaeyvvrdielse..dgkekdirkitqfhflGwpdvGvpdypsdlmrlvkkvr.hltskenhranivvhcsaGv
GRTGTFIAIDSLMDQMMMEGVVDVYGFVAQMRTQRNFMVQTHEQYAFIYDVLRDASLCGITEIP
||||..|..| |.|.| | |||| || ..| ||| .|| || ||| | . | | ...
GrtGvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysalleehlfghsdva
|
|||||||||
subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 6-266 | 4e-80 | 264.4 | In-house | 9-263 (284) | alignment | ||
Range on Protein: 6-266
Range on HMM: 9-263/284.0
HLGP-RATFEAAQTPYNKTKNRYPNILPYDHSRVVLRARKDSHGSDYINANFVDGYGCPQKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGdtehklRS
.||. .. . | . || |||. .||..|...| |. .|||||| |. || ..||||.|||| .|..||||.||| |.|||.| .
klgvngtdqtfanldqnkdknrighilafdknvvklerliGeefsdyinasfitGyqrkdkyiatqGPldntladfWrmiweyncstivllt......kd
DCERYWPEDGHQEYGDVAVSVVDVTHMTDWTVRTFLVWVRLHpeCMDKREVTQFQFTAWPDQGVPENTAPLIIFHHKYRyHLSS--EETGPILVHCGAGV
| .||| .. .... |.| |. ...|| . . . |.|...|| | |||.|||. ...|. . .| | ||.| .. .|.||| |||
kcsqywplkivikeerfkvkvdsveeseeyvvrdielsedgk..ekdirkirqfhflgwpdvgvpdypsdlmrlvkkvr.hltskenhranivvhcsagv
GRTGTFIAIDSLMDQMMMEGVVDVYGFVAQMRTQRNFMVQTHEQYAFIYDVLRDASLCGITEIP
||||..|..| |.|.| | |||| || ..| ||| .|| || ||| | . | | ...
grtgvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysalleehlfghsdva
|
|||||||||
subfamily_PTPRA_pd | Subfamily PTPRA | 7-273 | 3.8e-94 | 310.3 | In-house | 44-310 (330) | alignment | ||
Range on Protein: 7-273
Range on HMM: 44-310/330.0
LGPRATFEAAQTPYNKTKNRYPNILPYDHSRVVLRARKDSHGSDYINANFVDGYGCPQKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTEHKLRSDC
.||.|.|. || |||..||||||.|||.| .. . |||||| |.||| .|.||||||..||..||||.|||. .||||| . . . .. |
gpiqatlelaskeenkeknrvvnilPydfsrvilsvkeGveesdyinasfidGykekdkfiaaqGPkeetvedfwrmiweqksativmltelkerkeekc
ERYWPEDGHQEYGDVAVSVVDVTHMTDWTVRTFLVWvRLHPEC--MDKREVTQFQFTAWPDQGVPENTAPLIIFHHKYRyHLSSEETGPILVHCGAGVGR
..|||..| ||.. |.| |.| . |.||| ||| .| .. ..| |.|| ||.||| ||| .. .. . .| . .| ..||| ||| |||||
aqywPdeGlvtyGnirvevedetvlvdytvrkflvq.qlpdatrekksrlvrqfhftswPdvGvPfepiGmlkllkkvk.klnqqsagpivvhcsaGvGr
TGTFIAIDSLMDQMMMEGVVDVYGFVAQMRTQRNFMVQTHEQYAFIYDVLRDASLCGITEIPSQEIASS
|||||..|...... |..|||..|| ..|.|| |||| ||| ||| ||.. | | ||. . .
tGtfivldavlervkaerkvdvfefvkrlrlqrpqmvqtdeqyefiykvlleyylygdteldvsslekh
|
|||||||||
0040438 | (Phosphotyrosine protein) phosphatases II | 7-272 | 1.7e-92 | 305.3 | In-house | 30-290 (317) | alignment | ||
Range on Protein: 7-272
Range on HMM: 30-290/317.0
LGPRaTFEAAQTPYNKTKNRYPNILPYDHSRVVLRARKDSHGSDYINANFVDGYGCPQKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTEHKLRSDC
| . |.. |. | || |||||.|||||||||.| . ..||||||..|||. ...|.||.|||| .|. ||||..|| |.|.|||| ..| . | |
lkld.tysvaelpenkdknrypdilpydhsRVkLsplggdldsdYInAsyvdgpnlkrkfIatqgPlpntvedFwrmvweqgvtvivmLteleelgrekc
ERYWPEDGHQEYGDVAVSVVDVTHMTDWTVRTFLVWVRlhpECMDKREVTQFQFTAWPDQGVPENTAPLIIFHHKYRYHLSsEETGPILVHCGAGVGRTG
..|||... ..|||. | ....... ..|.||. |. .. ..|.||.|..|.|||.|||... .|. | .. | .|. .. ||.|||| |||||||
aqYwplgetltygdftvtllseeelagitlrtlevedl...gdsesrtvthfhytgWpdhgvppspdllldfleavreale.dpggpvlVHCsaGvgRtG
TFIAIDSLMDQMMMEGVVDVYGFVAQMRTQRNFMVQTHEQYAFIYDVLRDASLCGITEIPSQEIAS
||||.. ...|. || |||. |...| ||. .||| ||| |.||.|.. ....| .| .| ..
tfiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrflydalleylkrkltlepaselkl
|
|||||||||
0046845 | (Phosphotyrosine protein) phosphatases II | 7-263 | 9.6e-92 | 302.6 | In-house | 12-279 (284) | alignment | ||
Range on Protein: 7-263
Range on HMM: 12-279/284.0
LGPRA--TFEAAQTPYNKTKNRYPNILPYDHSRVVLRARKDS-HGSDYINANFVDGY-----GCPQKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDT
| . ....|. | |..||||..|||||||||.|. ... ..||||||..|||| ...|.||.|||| .|..||||..||.....|||| ..
ltvklllslsvallpenlsknRykdilpydhsRVklksldgdledsdYinAsyvdgydldltyikkkfIatqgPlpntvedFwrmvweqnvrvIVmltel
EHKLRSDCERYWPEDG-HQEYGDVAVSVVDVTHMTDWTVRTFLVWVRlhpE-CMDKREVTQFQFTAWPDQGVPENTAPLIIFHHKYRYHLSS-EETGPIL
. . | |..|||..| ..|||. | ....... |.||||. . . . |.||.|..|.|||.|||.....|. | .. | .|.. . |||.
vengrekcaqYwplegevltygdftvtllseevkddytvrtleltnl...gytgesrtvthfhytswpdhgvppspedlleflrlvrellenlpgggpiv
VHCGAGVGRTGTFIAIDSLMDQMMMEG---VVDVYGFVAQMRTQRNFMVQTHEQYAFIYDVLRDASLCGIT
||| |||||||||||.| |..|. || .|||.. |...|.||..|||| ||| |.|..| .. ....|
VHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvqtleqyrfvyealleylklklt
|
|||||||||
0045098 | (Phosphotyrosine protein) phosphatases II | 7-256 | 6.2e-81 | 267.1 | In-house | 19-270 (278) | alignment | ||
Range on Protein: 7-256
Range on HMM: 19-270/278.0
LGPRATFEAAQTPYNKTKNRYPNILPYDHSRVVlrarkdshgsDYINANFVDGYgcPQKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTEHKLRSDC
||. ... |. . |. ||||..|||||||||. |||||...||| |.|.||.|||| .|. ||||..|| |.|.|||| . ... | |
lgipseitpalylgnldknRykdilpydhsrVk..........dYINAsyidgy..pkkfIatqgPlpstvadfwrmlwelgitvivmltelvelgrekc
ERYWPEDGHQEYGDVAVSVVDVTHMTDWTVRTFLVWVR-LHPECMDKREVTQFQFTAWPDQGVPENT--APLIIFHHKYRYHLS------------SEET
..||||.|...|||. | ....... |.|.||.||. ...| .|.||..... ||| |||... .... . | .|. ..
aqywpeggsltygdftvtllseevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllsslllldsg
GPILVHCGAGVGRTGTFIAIDSLMDQMmmEGVVDVYGFVAQMRTQRNF-MVQTHEQYAFIYDVLRD
||.|||| ||||||||..|.. ..... ||.||.. |...|.||.. .||. ||| |.|..|..
gpvlVHCsaGvgRtGtlvaaylmlell..eggvdlleavkelrsqRpglavqnleqyrflyeflle
|
|||||||||
subfamily_PTPN9_pd | Subfamily PTPN9 | 7-253 | 4.8e-77 | 253.9 | In-house | 28-285 (297) | alignment | ||
Range on Protein: 7-253
Range on HMM: 28-285/297.0
LGPRATFEAAQTPYNKTKNRYPNILPYDHSRVVLRARKDSHGSDYINANFVDGYGCPQKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTEHKLRSDC
. ||.|.... | .|||| ..| ||..|||| ... . |||||||||||| .. .||.|||| .|..||||..||. . .||| .. . | |
epveGtflasklranleknrytdvlcydetrvvlakvdedeasdyinanfvdGykqkkafiatqGplkktvsdfWrmvWeqevlvivmttrvvergrlkc
ERYWP--EDGHQEYGDVAVSVVDVTHMTDWTVRTFLVWvrlHPECMDKREVTQFQFTAWPDQGVPENTAPLIIFHHKYRYHLSS-------E-----ETG
.||| |. .|.||. ||.|.| .. |..||.. . . . ..|.|| |||..||| |||...| |. . .| | . .. | .
gqyWpleeessaefgdlsvsnveveeeedykvrvleik...nvkteesrkvthfqflsWPdyGvPssaaslldvlekvrekqalavkelgdewkghpsgP
PILVHCGAGVGRTGTFIAIDSLMDQMMMEGVVDVYGFVAQMRTQRNFMVQTHEQYAFIYDV
||.||| ||.|||||||..| .... ..|.||| | ..|||| |..|| |||.| |
PivvhcsaGiGrtGtfitldiclsrleevgtvdvvetvkllrtqrafsiqtpeqyefcyla
|
|||||||||
subfamily_ptpA1_pd | Subfamily ptpA1 | 7-217 | 5e-48 | 158.8 | In-house | 34-255 (418) | alignment | ||
Range on Protein: 7-217
Range on HMM: 34-255/418.0
LGPRATFEAAQtPYNKTKNRYPNILPYDHSRVVLRARKDSHGSDYINANFVDGyGCPQKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTEHKLRSDC
.|| | | . .| .|||| |||| .|.|| |. .| ||||||||..|| |...|..|||| .|| ||||..||. | |||| . | |
vgpsetsegdk.khntsknrytnilpvnhtrvqlkkiqdkegsdyinanyidg.aypkqfictqgplpntiadfwrmvwenrcriivmlsresencrikc
ERYWPED-----------GHQEYGDVAVSVVDVTHMTDWTVRTflVWVRLHPECmDKREVTQFQFTAWPDQGVPENTAPLIIFHHK-----YRYHLSSEE
.|||||. | . .| .| .|.| . . . | .|| | . |..||.|. |||. .|. | |. . | . ||.
drywpeqiggeqfsiygngnevfgtysvelveviqdpereiit..rnirltfeg.etrditqyqyegwpdhnipdhtqpfrqllhsitnrqnqiipssdr
TGPILVHCGAGVGRTGTFIAIDSLMDQ
||.||| ||||||||| . .| .
nvpiivhcsagvgrtgtfctavimmkk
|
|||||||||
subfamily_PTPRD_pd | Subfamily PTPRD | 8-285 | 2.1e-117 | 388.1 | In-house | 35-308 (564) | alignment | ||
Range on Protein: 8-285
Range on HMM: 35-308/564.0
GPRATFEAAQTPYNKTKNRYPNILPYDHSRVVLRARKDSHGSDYINANFVDGYGCPQKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTEHKLRSDCE
|.. |.|||. | || |||| ||..||||||||.. . .|||||||.|.||| ...|||.|||| |||.||||..||. ..||||| .| | . |.
gqqftweaankpaNkaKNRyanivaYdhsRVvLskvegdegsDYINAsfidgyrkrkayIAtqgPlaetiedFWRmvweqnsstiVmltkleEkgkvkch
RYWPEDGHQEYGDVAVSVVDVTHMTDWTVRTFLVwvrLHPECMDKREVTQFQFTAWPDQGVPENTAPLIIFHHKYRYHLsSEETGPILVHCGAGVGRTGT
.||||.|...||.. |.... ....| ..||| . . . ...|||.||.||.|||.||||....|. . .| | . ....|||.||| ||||||||
kYWPekgtetygeltVtleeeeeladyeirtfkl...kkkkssesreVrqFhFtsWPdhgvpesatslLdlirkvraln.epdagPivVhCSaGVGRTGt
FIAIDSLMDQMMMEGVVDVYGFVAQMRTQRNFMVQTHEQYAFIYDVLRDASLCGITEIPSQEIASSLLVLRDNDPDII
||.||...... |..||.|..|...|.|||.||||.|||.||.... .| || ||..|... . | |. ..|
fividamlerikeektvDiyqyvkalrkqRnamVqteeQYiFiheailealacgntevesenlkqhlqkLaeveedte
|
|||||||||
subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 8-283 | 6.6e-70 | 230.8 | In-house | 36-313 (325) | alignment | ||
Range on Protein: 8-283
Range on HMM: 36-313/325.0
GPRAtFEAAQTPYNKTKNRYPNILPYDHSRVVLRARKDSHGSDYINANFVDGYGCPQKYIAAQGPLTETIKDFWRLI--WEkgCTTIVMLGDTEHKlRSD
.. | ...| | || |||..|....|.||||| ..||. ||||||... . . ..||| |||.||.|.|||. |. |. .|.| ...
dgia.kkvamkpenkaknrfknvvaldksrvvletkkddpssdyinasylrddkkkdvflaaqaPltatindlWrlvldWr..csvvvvlneldlg.kdr
CERYWPED--GHQEYGDVAVSVVDVTHMTDWTVRTFLVWvrlHPECMDKREVTQFQFTAWPDQGVPENTAPLIIFHHKY-----RYHLSSEETGPILVHC
| |||.. ...| . |... . ...|. | . | .. . | | |||. .|.| ||.. | || . . | . .. ..||||||
cavywpkemgksktfGglevklrtieeisdyvhrvldvk...qvkkGetrsvkqfqlqswddmGvqkrpatlisilqlvkavservtantkastpilvhc
GAGVGRTGTFIAIDSLMDQMMMEGVVDVYGFVAQMRTQRNFMVQTHEQYAFIYDVLRDASLCGITEIPSQEIASSLLVLRDNDPD
|||||||.||.. |...... | ||..||| ..| .| ||.| .|| .||. | .| ..| |..| . . | |.. .|
saGvGrtGvfislysalakvieesrvdifgfvkklrkdrpsmvetvdqyiliyealveaymsgntdvpvssfeaklsslqernpl
|
|||||||||
subfamily_Cele-PTP-15_pd | Subfamily Cele-PTP-15 | 8-256 | 7.6e-33 | 108.7 | In-house | 24-268 (285) | alignment | ||
Range on Protein: 8-256
Range on HMM: 24-268/285.0
GPRATFEAAQTpyNKTKNRYPNILPYDHSRVVLRarkdSHGSDYINANFVDGYGCPQ-KYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTEHKLRSDC
| .|. | .. | ||| .. . .||||. | ||| |... | | ||..|||| ||. |||..|... . ..|| |
ppnctytayea..npdlnryadvrcieetrvvlk....nhdrdyihaswmrmpgkdqstyittqgplpetlsdfwhmiyqekiayvlmlctlfeggvekc
ERYWPEDGH--QEYGDVAVSVVDVTH-MTDWTVRTFLVWVRLHPECMDKREVTQFQFTAWPDQGVPENTAPLIIFhHKYRYHLSSEETgPILVHCGAGVG
|.|| ..| ... .. |. | . . . . . | |||| ||.. |.| . .|. .. .|. || ||| ||||
alyypeklgevvkfgkyeitlteckeeaiagtilnaltvintedasseplymnhvqvpwwpdqlapedarpmiel.ykwvkkvnpkek.picvhcsagvg
RTGTFIAIDSLMDQMMMEGVVDVYGFVAQMRTQRNFMVQTHEQYAFIYDVLRD
|| ||. || ..| . ... | .||. | ||.| |. |.| || .
rtatfvgidyatirimenpniemldivremramrfqavqshmqflflyvvlme
|
|||||||||
subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 9-287 | 1.3e-104 | 344.7 | In-house | 34-309 (318) | alignment | ||
Range on Protein: 9-287
Range on HMM: 34-309/318.0
PRATFEAAQTPYNKTKNRYPNILPYDHSRVVLRARKDSHGSDYINANFVDGYGCPQKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTEHKLRSDCER
.| . .| ||.|||| |||.|||.|| |. .....||||||||..||| ..|||||.||.|||.||||..||.....|||| ..| . . ..|
etvtslkslepvnkaknryanilaydhtrvkLqmlegeegsDyinanyidGyrrkkayiaaqaPlpetieDfWrmvWeqnsavivmltqeeergkakvhr
YWPEDGHQEYGDVAVSVVDVTHMTDWTVRTFLVWvrlHPECMDKREVTQFQFTAWPDQGVPENTAPLIIFHHKYRYHLSSEETGPILVHCGAGVGRTGTF
|||..| ..||.. | . . ....|...|.| | . |. ..|.| |...|.|||.||||..| |. . . .. ....|||.||| |||||||.|
yWPskgsrsygklvvelkeevelsdyvlrefkvt...rteeeesrqvrqyhytsWpdegvpesgaslldlvrqvskaqqksgagpivvhCsaGvGrtGvf
IAIDSLMDQMMMEGVVDVYGFVAQMRTQRNFMVQTHEQYAFIYDVLRDASLCGITEIPSQEIASSLLVLRDNDPDIIRQ
||.|.|.... |..|||...| |.|.||| ||||..|| |||||| .| .| ||. .....| . ||..||.. .
iavdillerikaealvDvfqtvkqlreqrnlmvqtedqyefiydvllealasgdtevdasdlrsrirelreqdpesgtt
|
|||||||||
subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 9-265 | 8.3e-86 | 282.9 | In-house | 44-297 (298) | alignment | ||
Range on Protein: 9-265
Range on HMM: 44-297/298.0
PRATFEAAQTPYNKTKNRYPNILPYDHSRVVLRARKDSHGSDYINANFVDGYGCPQKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTEHKLRSDCER
.... |.|..|.|| ||||..|...|.|||||.. .. . |||||| |...| . .||.|.|||||..||||...|. .||||| ..| . . ....
eeeekevarkpenkkkNRyadiialdssRvvLekedadeesdYiNAsflhaykgrnafiatqaPltetvedFWrmvteedigtiVmltnleeldktkyhk
YWPEDGHQEYGDVAVSVVDVTHMTDWTVRTFLVWVRLHPecmDKREVTQFQFTAWPDQGVPENTAPLIIFHHKYRYHLSSEETGPILVHCGAGVGRTGTF
|||..|...||.. ||. ...| .||.. | . . ..||| |..|| |||.|||||. .. . .| | . . |..|.| |||||.|||
ywPdegketygeitvsllskeefadlivrklkvskkkee...kerevrqlhftsWpdkgvpenatsvldllrkvrasqqqagnkpvivqCsaGvgRsGtf
IAIDSLMDQMMMEGVVDVYGFVAQMRTQRNFMVQTHEQYAFIYDVLRDASLCGITEI
|||||..... | ||||. | .|..| .|||.|||.|||.. .| .. .||
iaidsvlervkkeqvvDvfqvvkvlRkkrpgavqteeqYvfiyeavlealdsfndei
|
|||||||||
subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 10-254 | 2.4e-60 | 198.8 | In-house | 27-273 (287) | alignment | ||
Range on Protein: 10-254
Range on HMM: 27-273/287.0
RATFEAAQTPYNKTKNRYPNILPYDHSRVVLRArKDSHGSDYINANFVDGYGCPQKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTEHKLRSDCERY
||| ||. .. |||| ..||.|..||.| | . .||||||||.| .| ...||||||.. |..||||...|. ...... . | | .|
tatfkaaeelaavkknryadvlPiddtrvllsa.egelGsdyinanyvasytddeafiaaqgPiaatvrdfwravletrsasvitmtreveearlkcyky
WPEDgHQ--EYGDVAVSVVDVTHM-TDWTVRTFLVwvrLHPECMDKREVTQFQFTAWPDQGVPENTAPLIIFHHKYRYHL----SSEETGPILVHCGAGV
||| .. | .| ..| . . ...||.. . .. | . | | |... .|||.... . || | . . |. ...|.||..||. .|.
wPer.evPmrvGGysvvlldydikePeygvralrl...idletrearvvkqldllswPdkvlaPtavglirfvldvkqhielardasevGPlvvhddvGi
GRTGTFIAIDSLMDQMMMEGVVDVYGFVAQMRTQRNFMVQTHEQYAFIYDVL
||.|...|. |.... | ||| |...| .|. .||. |. ..|. |
GrsGillatlvlvsrledlGrvdvaavvirlreyraalvqavvqlrllyeal
|
|||||||||
subfamily_PTPN14_pd | Subfamily PTPN14 | 10-254 | 1.1e-56 | 187.0 | In-house | 38-292 (300) | alignment | ||
Range on Protein: 10-254
Range on HMM: 38-292/300.0
RATFEAAQTPYNKTKNRYPNILPYDHSRVVLRARKDShGSDYINANFVDGY--GCPQKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTEHKLRSDCE
|....|. | |. |||....|||...|| | . |.. ..|||| . | ..||.||||| |..|||...||.| . |||| ..| . . .
dallstaklpenaeknrfkdvlPyednrvelsptken.stgyinassikvsvggkersyivaqgPleltvqdfWqmvWeqgvqlivmlteeeedgkeksf
RYWPED----GHQEYGDVAVSVVDVTHMTDWTVRTFlvWVRlHPECMDKREVTQFQFTAWPDQGVPENTAPLIIFHHK---YRYHLSSEE-----TGPIL
.|.|.. . |.| |. ... . . ... .. | ..|.| .|.| |||.||||. . . . .. |.. .|| |.|
kyfPkleskkktvefgkfkvttkfsedsdsvittgl..klk.hlpskeertvwhlqytDWpdhgvPeDvkgflsyLeevqsvrrktnseveskeskPPvl
VHCGAGVGRTGTFIAIDSLMDQMMMEGVVDVYGFVAQMRTQRNFMVQTHEQYAFIYDVL
||| ||||||| | | |. . . ..|. .|..|.|| ..||| || |.|.||
vhCsaGvGrtGvlilsdlliatlehneeidikkvlarLreqrmllvqtlaqYkfvYkvl
|
|||||||||
0049772 | (Phosphotyrosine protein) phosphatases II | 10-258 | 2.2e-44 | 147.8 | In-house | 35-280 (314) | alignment | ||
Range on Protein: 10-258
Range on HMM: 35-280/314.0
RATFEAAQTPYNKTKNRYPNILPYDhSRVVLrARKDSHGSDYINANFVDGYgcpQKYIAAQGPLTETIKDF----------WRLI--WEKGCTTIVM---
. |. .|. . |..||||..|||.| .||.| . . .|||||||..|||. .|.||.|||| .|. || ||.. .. . .|||
eltilvadlflnrdknryldilpad.nrvil.pglpvsgsdyinasyvdgf...lkfIatqgpleitvvdfreepvlyyngwrmvlrgdlnvrdivmsrd
---------LGDTEHK--LRSDCERYwpedghqeygdvavSVVDVTHMTDWTvrtflvwvrlhPECMDKREV----TQFQFTAWPDQGVPENTAPLIIFH
|.. .| |.. .... . .. .. .. .|. |. . .. . .|| ..| . ...
evladelsrLdaAlgKtpllildgng..............neptaadlellk...........eelydpelferlgikylripvpDgsaplledfdefle
HKYRYhlssEETGPILVHCGAGVGRTGTFIAIDSLMDQMmmeGVvDVYGFVAQMRTQRN-----FMVQTHEQYAFIYDVLRDAS
. .. .. ||.|||| ||.||||||.... || .. || .. ....| .| .... ||| ||...|...
fieea....dkggpvlvHCkaGkgRtgtfvvaaylmkll...gv.sleealedvrlkRpinpnpgfieqleqyefilealleyl
|
|||||||||
subfamily_Sponge-PTP3_pd | Subfamily Sponge-PTP3 | 10-71 | 8.9e-15 | 48.7 | In-house | 37-95 (95) | alignment | ||
Range on Protein: 10-71
Range on HMM: 37-95/95.0
RATFEAAQTPYNKTKNRYPNILPYDHSRVVLRARKDshgSDYINANFVDGYGCPQKYIAAQG
|.. . . | |||. ||.||| .|||| ...| |||||| ||||| . ||||||
gapytvgsseanipknrflnifpydatrvvlttkrd...sdyinacfvdgyarkncyiaaqg
|
|||||||||
0045450 | (Phosphotyrosine protein) phosphatases II | 11-255 | 2.1e-85 | 282.4 | In-house | 45-301 (307) | alignment | ||
Range on Protein: 11-255
Range on HMM: 45-301/307.0
ATFEAAQTPYNKTKNRYPNILPYDHSRVVLRARKDS-HGSDYINANFV--------DGYGCPQKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTEHK
....|. | ||.||||..||||||.||.| ..| ..||||||..| ||| ...|.||.|||| ||..||||..||.|.|.|||| ... .
geysiallpenkdknrykdilpydhtRVklssldgsledsdYiNAsyvrvpllllldgydlkrkfIatqgPlpetvedFwrmlweqgvtvivmltelvel
LRSDCERYWPEDGHQ-EYGDVAVSVVDVTHMTDWTVRTFLVWVRlhPECMDKREVTQFQFTAWPDQGVPENTAPLIIFHHKYRYHLSSE-ETGPILVHCG
| | .|||..|.. .||.. | .....|. ..||||. |. .. |.||.|..|.|||.|||.....|. | .. | .|.. . ||.||||
grekcaqywPdegeeltygnftvtllseehldgytvrtlevtdl..dgtgesrtvthfhytgwpdhgvppsfeelldfieevrkaleelpkggpvlVHCs
AGVGRTGTFIAIDSLMDQMMMEGV---VDVYGFVAQMRTQRNFMVQTHEQYAFIYDVLR
|||||||||||.. ...|. ||. ||.. |...| || .||. ||| |.|..|.
aGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrflyeall
|
|||||||||
subfamily_Cele-PTP-14_pd | Subfamily Cele-PTP-14 | 11-253 | 3.4e-33 | 109.5 | In-house | 44-285 (310) | alignment | ||
Range on Protein: 11-253
Range on HMM: 44-285/310.0
ATFEAAQTpyNKTKNRYPNILPYDHSRVVLRARKDSHGsDYINANFVDGYGCPQKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTEHKLRSDCERYW
|.|| . . |||| ... | ||| |. | .. ||| ||.| . .| .|||| || ||||.|... . .|..| . .. | | ||
ltyeaykk..ymhknrysdvvcldtsrvklkidksrye.dyihanyvktnylrstficsqgplqhtiidfwrmifqeraesilllckvgeegrpkcvgyw
PEDGHQE-YGDVAVSVVD----VTHMTDWTVrTFL---VWVRLHPECMDKREVTQFQFTAWPDQGVPENTApliifHHKYRYHLSSEETGPILVHCGAGV
| | | || . |. . . . .| ||. | | | ... |. .. |||.|||.. | . |. || .||| ||.
pslgvtetygcirvtnlsesseefeicnlav.tfvpdnvpvdeqpanlkelrvslikwpnwpdrgvpdekc.....htvpqrllaqvrhgpcvvhcsagk
GRTGTFIAIDSLMDQMMMEGVVDVYGFVAQMRTQRNFMVQTHEQYAFIYDV
.|... .|.. .|.. ||. ..... .| .||. || .| |
drlyvvvalklkidkldrglkvdaeevktellksraiciqtelqyliidrv
|
|||||||||
subfamily_egg_pd | Subfamily egg | 11-254 | 1.2e-27 | 91.5 | In-house | 30-266 (307) | alignment | ||
Range on Protein: 11-254
Range on HMM: 30-266/307.0
ATFEAAQTPYNKTKNRYPNILPYDHSRVVLRARKDSHGSDYINANFVDGYGCPQKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTEHKlrSDCERYW
... | . |..| | . . | ||| |. |. . |.| || |.| ..| || || .| .||||..... . |||| . . || ||
islttaasdnnlekarskrvhckdssrvklelrrGqylddfihanrvkGkpllnefilaqaplkntvddfwrmvfqeevqyivmltsrkes..erceyyw
PEDGHQE--Y--GDVAVSVVDVTHMTDWTVRTFLVWVrLHPEcmdkREVTQFQFTAWPDQGVPENTAPLIIFHHkYRyhlssEETGPILVHCGAGVGRTG
| . . | . . ..| . .| | . . . .. .| . . . . . || .. . | . . |..|.. || ...
pkaesdslvtvpGslrienlkvdskadplfrvtklkl.vGgd....deerflehwqgdvnnssdvysplrvlrk.lr.....nlskpvvvqdilGvskaa
TFIAIDSLMDQMMMEGVV--DVYGFVAQMRTQRNFMVQTHEQYAFIYDVL
|..||. . ... .. | | .| .|.. |.. .| |.| ..
tlvaieiallsllrGpitkslvlravvflrlrrrlsvesvllylfvyrlv
|
|||||||||
subfamily_PTPRG_pd | Subfamily PTPRG | 12-287 | 1.3e-92 | 305.8 | In-house | 38-319 (563) | alignment | ||
Range on Protein: 12-287
Range on HMM: 38-319/563.0
TFEAAQTPYNKTKNRYPNILPYDHSRVVLRARKDSHGS-DYINANFVDGYGCPQKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTEHKLRSDCERYW
. |..| | || |||| ||..||.||| |. . ... ||||||..||| ...||.||||..|..||||.|||. ..|||. . ... | .|..||
daehsqkpenkrKnRylnivaydrsRvklsplpgkkkklDYinAnyidGyqkskafiatqgplkdtfddFWrmiWeqnvaiivmitnlvergrrkcdvYW
PEDGHQEYGDVAVSVVDVTHMTDWTVRTFLVWV---RLHPECMDKREVTQFQFTAWPDQGVPENTAPLIIFHHKYRyHLSSEETGPILVHCGAGVGRTGT
|.|. ..|| . | .. ... ||||. . . . .| ....|.|...| |||.|||| ..| .|| .| .|.|||.||| ||||||||
PkdesetygalqvtlieeevlalytvrtlviknlklkkkkqcdteklvrqyhytkWPdhgvPehslpvLifvkkss.aankaeaGPivvHcsaGvgrtGt
FIAIDSLMDQMMMEGVVDVYGFVAQMRTQRNFMVQTHEQYAFIYDVLRDASLCGITEIPSQEIAS---SLLVLRDNDPDIIRQ
.|..|.|. |. | .|.|.||. ..|.||||.|||.||| |..|.| .| . . ||. .... . | .. .||.
yivldtllkqiqqenavnvfgflkhiraqRnflvqteEqYiflhdalleaiasketellaeqveelknctpyleqqykniiqf
|
|||||||||
0040439 | (Phosphotyrosine protein) phosphatases II | 12-256 | 1.1e-83 | 275.9 | In-house | 2-244 (249) | alignment | ||
Range on Protein: 12-256
Range on HMM: 2-244/249.0
TFEAAQTPYNKTKNRYPNILPYDHSRVVLRARKDSHGSDYINANFVDGYGCPQKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTEHKLRSDCERYWP
... |. | || |||||.|||||||||.| .. .||||||...||| .....||.||||.||..||||..|| |.|.|||| ... . | .|..|||
eysvallpenkdknrypdilpydhsrvklsilpglflsdyinAsyidgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqywp
EDGHQEYGDVAVSVVDVTHMTDWTVRTFLVWVRlhpECMDKREVTQFQFTAWPDQGVPENTAPLIIFHHKYRYHLSSE-ETGPILVHCGAGVGRTGTFIA
..|..||||. | ...|... |.||||. .. .. ..|.|...|.| |||.|||.....|. | .. | .|.. . ||.|||| |||||||||||
lggsleygdftvtllsvevkddytvrtleltnl...ydgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtfia
IDSLMDQMMMEGVVDVYGFVAQMRTQRNFMVQTHEQYAFIYDVLRD
.. ...|. |. ||.. |...|.||. .||. ||| |.|..|..
aylmleqlekelgvdleeavkllrsqRpgavqnpeqyrflyealle
|
|||||||||
subfamily_PTPN6_pd | Subfamily PTPN6 | 12-255 | 6.4e-77 | 253.6 | In-house | 43-294 (306) | alignment | ||
Range on Protein: 12-255
Range on HMM: 43-294/306.0
TF--EAAQTPYNKTKNRYPNILPYDHSRVVLRaRKDSHGSDYINANFVD--GYGCPQKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTEHKLRSDCE
.. . .. | ||.|||| ||||.||.||.|. ... ||||||||... | ..|||.|| |..|..||||..|.. .. |||. . .. |
llsrkegakpenkeknryknilPfDhtrvilk.epsvpgsdyinanyikkevkgsdksyiatqgclettvsdFWrmvwqensrvivmttkevErgkekCa
RYWPEDGH-QEYGDVAVSVVDVTHMTDWTVRTFLVWVRlhPECMDKREVTQFQFTAWPDQGVPENTAPLIIFHHKYRYHLSS---EETGPILVHCGAGVG
||||. . .|||.. |. |. ....|...|...| . . ..||| |..|..|||.|||... .. | .. . . .. .|.|||.||| ||.|
rYWPdeeekeeyGkisvtnvseksladYilRelsvskk..kkkkeerevfqyhfksWPdhgvpkdpgavLdfledvnrkqeeleeaeagpivvhCsaGiG
RTGTFIAIDSLMDQMMMEGV---VDVYGFVAQMRTQRNFMVQTHEQYAFIYDVLR
|||||| || |..... .|. .|.. .| ..|.||. .|||..|| |.| ...
RtGtfiviDillkliekkgldadidiqklvksvreqrsglvqteqqykfvykaik
|
|||||||||
subfamily_PTPRN_pd | Subfamily PTPRN | 12-253 | 7e-59 | 193.9 | In-house | 47-287 (297) | alignment | ||
Range on Protein: 12-253
Range on HMM: 47-287/297.0
TFEAAQTPYNKTKNRYPNILPYDHSRVVLRARKDSHGSDYINANFVDG-YGCPQKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTEHKLRSDCERYW
| |.|... | .|||. ..|||||||| |... ... |||||| .. |||.||||..|. |||...||.|.. ||.| |.. . |.|||
tkevakaeknvkknrskavlpydhsrvklkeeasaeksdyinasaildhdprapayiatqgplastvadfwqmvweqGvvvivnltrleeegvkqckryw
PEDGHQEYGDVAVSVVD-VTHMTDWTVRTFLVWvRLhpECMDKREVTQFQFTAWPDQGVPENTAPLIIFHHKYRYHLSSeETGPILVHCGAGVGRTGTFI
|..|.. |. | .| |. ||.| . | . . | |||| | .||..||| .. .|. | | . ||.||| .|.||||..|
pdeGsevyhiyevhlvsehiwcddylvrsfylk.nl..qtsetrtvtqfhflswpeegvPasaksllefrrkvnksyrG.rscpivvhcsdGaGrtGvyi
AIDSLMDQMMmEGV--VDVYGFVAQMRTQRNFMVQTHEQYAFIYDV
.|| ...... || .|. . .| ||. .|.|..|. |.. .
lidlvlnrll.kGvkeidiaatlehlrdqrpglvktkdqfefalta
|
|||||||||
subfamily_Cele-PTP-6_pd | Subfamily Cele-PTP-6 | 12-256 | 3e-43 | 143.0 | In-house | 34-275 (307) | alignment | ||
Range on Protein: 12-256
Range on HMM: 34-275/307.0
TFEAAQTpyNKTKNRYPNILPYDHSRVVLRArkDSHGSDYINANFVDGYGCPQKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTEHKLRSDCERYWP
| || .. | |||| .. |..|.|.. | |||| ||.. |.|.|.||||| .|. .|| .. .. ...|| .. . ||.|||
tveafsa..ntdknryqdvkcqdkgrivvkf..dglasdyihanylgiaikpkkficaqgplentqysfwamaiqekvesvimlckvielakikceqywp
EDGHQE--YGDV--AVSVVDVTHMTDWTVRTFLVWVRLHPEC-MDKREVTQFQFTAWPDQGVPENTAPLIIFHHKYRYhlsseETGPILVHCGAGVGRTG
. |. .|. ..|| .. . .. |. . . | ....|.. |||.|||. | . . || .| |..||| |||||.|
leegqklvfgeapntisvanlgakklapdedlinvttlkvdwaqksrtiqhlqwenwpdrgvpqinltainlleavry.....dtnpvvvhcsaGvGrsG
TFIAIDSLMDQMMM-EGVVDVYGFVAQMRTQRNFMVQTHEQYAFIYDVLRD
| .|| ..|.|. . |. .| ..|.||.. .|| || ... || .
tivaislvqdkmiaGinckdmkklveelrsqrhyaiqteaqylylhrvlle
|
|||||||||
subfamily_Cele-PTP-10_pd | Subfamily Cele-PTP-10 | 12-255 | 3.8e-35 | 116.0 | In-house | 45-286 (305) | alignment | ||
Range on Protein: 12-255
Range on HMM: 45-286/305.0
TFEAAQTP-YNKTKNRYPNILPYDHSRVVLRarKDShGSDYINANFVDGYGCPQK-YIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTEHKLRSDCERY
.|.| |.. ..||||| .. |.| | | | | |||| ||.| |.| .|.||||| .|| .|| .. .. |||| | . | .|
afnanqsadiaitknryqdvpcqdqsavkld..kps.psdyihanyvgcpmipekrficaqgpldqtidefwwmviqnkveqivmlcktvelgklkcaqy
WPED-GHQ--EYGDVAVSVVDVTHMTDWTVRTFLVWVRLHPECMDKREVTQFQFTAWPDQGVPENTAPLIIFHHKYRyhlssEETGPILVHCGAGVGRTG
|| | . . . | | .. . . ..| .| | ..|.| |||.||| . . | ||.||| ||.||||
wpaaqgeklelksgivvenvsgskpmerdaeiqitllnltysgdqkmsvrhlqwtewpdrgvppckltslellsair.....gskvpivvhcsagigrtg
TFIAIDSLMDQMMMEG-VVDVYGFVAQMRTQRNFMVQTHEQYAFIYDVLR
| .||. ..... . . . .| .| || | .|. || ||. |.
tivaieyilekiaenkpcppmpelvkalrdqrafsiqndvqylfihrvml
|
|||||||||
subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 12-178 | 2.3e-33 | 110.4 | In-house | 24-189 (297) | alignment | ||
Range on Protein: 12-178
Range on HMM: 24-189/297.0
TFEAAQTPYNKTKNRYPNILPYDHSRVVLRarKDSHGSDYINANFVDG--YGCPQKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTEHKLRSDCERY
.| .|. . |||| .|| .| .|| |. . ..|||||..| . ||| ||||| .|..|||.|..|.. .|||. . |. | |
sfssakrnsslrknryrdilatddtrvkll..rviterdyinadyvvfpdeeadlkyilaqGplsatvddfwtlvaeqdvrvivmvaklqedGrdkcapy
WPED--GHQEYGDVAVSVVdvTHMTDWTVRTFLVWVRLHPEcMDKREVTQFQFTAWPDQGVPENTAPLIIF
||. . .. ||| | . ....| | .| ..| ..| |. || .||| ||| . | |
wpsvvqerlkagdvvvefl..sstsdefdrviltelqliyr.sesrvvrhvqflswpdhGvpsdledlvrf
|
|||||||||
0039614 | (Phosphotyrosine protein) phosphatases II | 13-260 | 1.5e-87 | 289.1 | In-house | 48-291 (297) | alignment | ||
Range on Protein: 13-260
Range on HMM: 48-291/297.0
FEAAQTPYNKTKNRYPNILPYDHSRVVLRARKDS-HGSDYINANFVDGYGC-PQKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTEHKLRsDCERYW
.. |. | ||.||||..|||||||||.| ... ..||||||..|||| . ..|.||.||||.||..||||..|| |.|.|||| ... . | |..||
ysiallpenkdknrykdilpydhsrvklkpedgvdldsdYinAsyvdgydlltrkfIatqgPlpetvedFwrmvweqgvtvivmLtklvelgr.kcaqyw
PEDGHqEYGDVAVSVVDVTHMTDWTVRTFLVWVrlhPE-CmdkREVTQFQFTAWPDQGVPENTAPLIIFHHKYRYHLSSE-ETGPILVHCGAGVGRTGTF
||.| .|||. | ...|.| ..||||. |. . |.||.||.| ||| |||.... |. | .. | .|.. . ||.|||| |||||||||
peegg.tygdftvtllkvehldgytvrtlevtn...nges...rtvthfqytgwpdhgvppslellleflelvrealaelpkggpvlVHCsaGvgRtGtf
IAIDSLMDQMMMEGVVDVYGFVAQMRTQRNFMVQTHEQYAFIYDVLRDASLC
||.. ...|. || |||. |...| ||. .||| .|| |.||.|.. ..
iaaylmleqlekeggvdvleavkelreqRpgavqtpsqyrflydallellkr
|
|||||||||
subfamily_PTPRK_pd | Subfamily PTPRK | 13-282 | 1.9e-86 | 284.8 | In-house | 35-301 (314) | alignment | ||
Range on Protein: 13-282
Range on HMM: 35-301/314.0
FEAAQTPYNKTKNRYPNILPYDHSRVVLRARKDSHGSDYINANFVDGYGCPQKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTEHKLRSDCERYWPE
..||. |..|||. .||.||.|||.| . .. ||||||...|.| |...|..|||| ||.||||||.....|..|||| . .. | | .||||
wdaakkdenreknrsgdilaydrsrvflitidgdpssdyinaalidsykrpaafivtqgPlqetvkdfWrlvydencasivmltelvevgrvkClkyWPe
DGHQeYGDVAVSVVDVTHMTDWTVRTFLVWvRLHPECMDKREVTQFQFTAWPDQGVPENTAPLIIFHHKYRYhLSSEETGPILVHCGAGVGRTGTFIAID
|... |||. | .|... .. ||.| | .|. ..||| ||||..||| .|| . |. . .. . || |.|.||| || ||||||||||
dtev.ygdikvelvetellaelvvrifrve.klargqeeirevrqfqflgWpdhdvPvsatgllklvrrvkk.sqeeeaGrivvhCsaGaGrtGtfiaid
SLMDQMMMEGVVDVYGFVAQMRTQRNFMVQTHEQYAFIYDVLRDASLCGITEIPSQEIASSLLVLRDNDP
...| . ||||||. | ..|... ||.|.||| |||||. .| ||| | || |. . | ||
ivldmieregvvdvfnavktlrsrkvnmveteeqykfiydvileaclcgetaipvsefkalylesirldp
|
|||||||||
subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 13-267 | 4.6e-85 | 280.3 | In-house | 41-288 (315) | alignment | ||
Range on Protein: 13-267
Range on HMM: 41-288/315.0
FEAAQTPYNKTKNRYPNILPYDHSRVVLRARKDSHGSDYINANFVDGYGCPQKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTEHKLRSDCERYWPE
.. |. || |||| ||..||.||| | . .|||.||||.||| ...|||||||.....||||||..|. ...|||| .. .. .. .|.|||.
ldvakkienkqknryiniiaydksrvqlpllendphsdyvnanfidGynkkrryiaaqgpnvasvkdfwrlvfeedigkivmltnlvegekrkaekywpd
DgHQEYGDVAVSVVDVTHMTDWTVRTFLVWVRlhpecMDKREVTQFQFTAWPDQGVPENTAPLIIFHHKYRYHLSSEEtGPILVHCGAGVGRTGTFIAID
. . || ..|. .. . |..||||. | .. . ||| |...|.||| |||. | ||. .. . . | .. |.|.||| ||||||||||..|
k.kviyGkitvtrkseevnteytvrtlsvvfg.....dnirevvqlhytswpdmgvpkytiplmnlirtvkqhhtnsv.gaivvhcsaGvGrtGtfitld
SLMDQMMMEGVVDVYGFVAQMRTQRNFMVQTHEQYAFIYDVLRDASLCGITEIPS
...||. .| ..||| |. ..| .| |||. ||| ||||.| .. .|| | |
avldqaeaenaidvynfitgvrqnrikmvqvaeqyqfiydalletfvcgdtsiaq
|
|||||||||
subfamily_Ptp69D_pd | Subfamily Ptp69D | 13-273 | 4.8e-84 | 277.1 | In-house | 40-301 (307) | alignment | ||
Range on Protein: 13-273
Range on HMM: 40-301/307.0
FEAAQTPYNKTKNRYPNILPYDHSRVVLRARKDSHGSDYINANFVDGYGCPQKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTEHKLRSDCERYWPE
.... |. ||||..| ..|. ||.|. . .. ||||||.|. || .|.||||.|. .||.||||.|.|. |.|||| . . | | .|..|||.
tkvsekkenalknRyedikafDktRvkLkkingkedsdYinasfikgykekkkfiaaqdPveatigDfWRmiaeqevtlivmlsnlteknrkkcakYWpi
DGHQEYGDVAVSVVDVTHMTDWTVRTFLVWVRL--HPECMDKREVTQFQFTAWPDQGVPENTAPLIIFHHKYRYHlSSEETGPILVHCGAGVGRTGTFIA
. ..|||. | .|. ...|.. |.. | .| |.|.|.|...|.|.| ||| . |. . .. | . . . .||.||| |||||.|.|.|
edevqygdilvklvseekhsdyiiReldvskkkeesgevedsrkvvqyhytgWkDskvPevargllklieqvrel.yklnrsPivvhCsaGvgrsgifva
IDSLMDQMMMEGVVDVYGFVAQMRTQRNFMVQTHEQYAFIYDVLRDASLCGITEIPSQEIASS
.|||..|. | ||.. .| ..| |||..|| ||| |.| | | | | |.. ......
ldsllqqlkaedkvdifetvkdLrsqRnllvqsleqYvflyralldyssygdtdedvddleda
|
|||||||||
subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 13-270 | 1.1e-82 | 272.6 | In-house | 38-295 (305) | alignment | ||
Range on Protein: 13-270
Range on HMM: 38-295/305.0
FEAAQTPYNKTKNRYPNILPYDHSRVVLRARKDSHGSDYINANFVDGYGCPQKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTEHKLRSDCERYWPE
.. .. ||.|||. .| ..|..|. |..... . ||||||..|||| .|||.||||| .|..||||||.| .||||| .. .. |..||||
idvgkkeankaknrlkeitlldddriiltekeslddsdyinasyvdgykrkkkyivaqgPlkntvadfWrliveekvstivmltklveggkdkCrqYWpe
DGHQ--EYGDVAVSVVDVTHMTDWTVRTFLVWVRLHpeCMDKREVTQFQFTAWPDQGVPENTAPLIIFHHKYRYHLSSEETGPILVHCGAGVGRTGTFIA
. |.|.. | . . ....|.. | . . .. . ..| |.|.|.| |||.|||. .. |. . .. . . .... |.|||| |||||||.|||
sktekkefgefsvelksektasdyieRklkisiede..dkesrtvlqyqltdWPdhGvpqfatsllslikrvqkdqkkdkgvpllVhCsagvgRtGvfia
IDSLMDQMMMEGVVDVYGFVAQMRTQRNFMVQTHEQYAFIYDVLRDASLCGITEIPSQEI
.| .... |.||||.. . |.|..| |||| .|| |..|.| . || |.| . .
vdialerlkkEevvdvfevlkqlRskrmkmvqtldqYvflhdaldelitcgdtsiigsnl
|
|||||||||
0037934 | (Phosphotyrosine protein) phosphatases II | 13-255 | 4.3e-76 | 250.9 | In-house | 2-239 (243) | alignment | ||
Range on Protein: 13-255
Range on HMM: 2-239/243.0
FEAAQTPYNKTKNRYPNILPYDHSRVVLrarkdsHGSDYINANFVDGYGcpqKYIAAQGPLTETIKD----FWRLIWEKGCTTIVMLGDTEHKLRSDCER
| |. |.|..||||..|||||||||.| ||||||||...... ..|| ||||.||..| |||..|| |.|.|||| ... . | .|..
fsiallpenlsknrysdilpydhsrvkl......egsdyinanliyvtp...rliatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaq
YWPeDGHqEYGDVAVSVVDVTHMTDWTVRTFLVWVRLHPECMdkREVTQFQFTAWPDQGVPENTAPLIIFHHKYRYHLSS-------EETGPILVHCGAG
||| ... .|||. | .....|. |.||||.|.. .... |.|.......|||.|||.....|. |... | .... . ||.|||| ||
ywp.gev.tygdftvtllseehlddytvrtlllenldlddlt..rlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaG
VGRTGTFIAIDSLMDQMmmeGvVDVYGFVAQMRTQRNF-MVQTHEQYAFIYDVLR
||||||.||.. ..... | ||.. |...|.||.. .||| .|| |.|..|.
vgRtGtliaaylmllll...g.vdleeavkllreqRpgkavqtpsqyrflyeall
|
|||||||||
0042113 | (Phosphotyrosine protein) phosphatases II | 14-255 | 7.6e-82 | 269.7 | In-house | 2-240 (245) | alignment | ||
Range on Protein: 14-255
Range on HMM: 2-240/245.0
EAAQTPYNKTKNRYPNILPYDHSRVVLRARKDSHGSDYINANFVDGYGCPQKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTEHKLRSDCERYWPED
. |. | ||.||||..||||||.||.| . . .||||||..|||| ...|.||.||||.||..||||..|| |.|||||| ..| . | .|..|||..
svallpenkdknrysdilpydhtrvklspdggdldsdyinasyvdgyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywplg
GHQEYGDVAVSVVDVTHMTDWTVRTFLVWVRlhpECMDKREVTQFQFTAWPDQGVPENTAPLIIFHHKYRYHLSSEETGPILVHCGAGVGRTGTFIAIDS
....|||. | .....|. |.||||. |. . .|||...... |||.|||.... |. |.. | .|.. . ||.|||| |||||||||||..
esltygdftvtllseehlddytvrtlevtnl...gddesrevihyhylpwpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaayl
LMDQMMMEGVVDVYGFVAQMRTQRNFMVQTHEQYAFIYDVLR
...|. |. |... |...| || .||| .|| |.|..|.
mleqlekelgvsleeavkelrsqRpgavqtpsqyrflyeall
|
|||||||||
subfamily_PTPN12_pd | Subfamily PTPN12 | 14-256 | 1.3e-76 | 252.3 | In-house | 33-275 (290) | alignment | ||
Range on Protein: 14-256
Range on HMM: 33-275/290.0
EAAQTPYNKTKNRYPNILPYDHSRVVLRARKDSHGSDYINANFVDGYGCPQKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTEHKLRSDCERYWPED
||.....|..|||| .|||||.|||.|. ....|||||||||. | ...||||||||..|..||||.|||| . .||. . |||||||
eagekeenvkknrykDilPydksrvelskieeeegsdYinanfikgvegkleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkkCerYWpee
GHQE--YGDVAVSVVDVTHMT-DWTVRTFLVWVRlhpecMDKREVTQFQFTAWPDQGVPENTAPLIIFHHKYRYHLSsEETGPILVHCGAGVGRTGTFIA
|..| .|.. |.. . ... |...||. | .. ..|.|.||..|||||.|||... .|. . .. | . . .| |..||| |||||||| ||
geeelefgefevtleeekavdddflirtLkveaq.....kesrkvyqfhYtaWPDhgvPssaksllelielvrelqe.sedaPlvvhCsaGvGrtGtiia
IDSLMDQMMMEGV---VDVYGFVAQMRTQRNFMVQTHEQYAFIYDVLRD
|| ... | . .||. |...|.||. .|||.||| ..| . .
idyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavae
|
|||||||||
subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 14-266 | 8.8e-74 | 243.2 | In-house | 37-285 (315) | alignment | ||
Range on Protein: 14-266
Range on HMM: 37-285/315.0
EAAQTPYNKTKNRYPNILPYDHSRVVLRARKDSHGSDYINANFVDGYGCPQKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTEHKLRSDCERYWPE-
.|... | .|||| ||||.|..||.| || |||||| .. .. . . |||.|||| ...||||..... |||||. . .. . | .|||.
rvaretinfkknryknilPldsarvkleviddsPdsdyinasyiksvdddkayiasqgPlkasvddfwrmvlqekvttivmvtkkqegdkikcrqywPdr
-DGHQEYGDVAVSVVDVTHMTDWTVRTFlvWVRlhpECMDKREVTQFQFTAWPDQGVPENTAPLIIFHHKYRYHlSSEETGPILVHCGAGVGRTGTFIAI
|.| . |..... || ..| . .| . ..| ||||||| |||.||...|. |. . .. . ... ..|||| ||||||| .|.|
kadsvefGsikvellsleadtdgvarkl..vtr...kseesrtvtqfqftewPdkGvdkqtssllklikevkad.ngkkefsllvhcsaGvGrtGvvisi
DSLMDQMMMEGVVDVYGFVAQMRTQRNFMVQTHEQYAFIYDVLRDASLCGITEIP
|. ..|. . .|||. || ..|..| ..|||.|.||||||.... | | |.
devvaqikrtrsvdvfnfvknlrakrpylvqteeeyafiydavledllwrntlil
|
|||||||||
subfamily_Urchin-PTP-4_pd | Subfamily Urchin-PTP-4 | 14-278 | 1.4e-58 | 193.2 | In-house | 38-256 (392) | alignment | ||
Range on Protein: 14-278
Range on HMM: 38-256/392.0
EAAQTPYNKTKNRYPNILPYDHSRVVLRARKDSHGSDYINANFVDGYGCPQKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTEH-Klrsdcerywpe
.||.. |. |||| |||||| .||.| |. |||.|| ..... . . |||.||| . ...||||..... |||.|. . .
tvaqkeinlkknryknilpydsarvkleviddipdsdylnasyipsfdnekayiasqgpnaaslddfwrmvfqenvttiamvtklkegd...........
dghqeygdvavsvvdvthmtdwtvrtflvwvrlhpECMDKREVTQFQFTAWPDQGVPENTAPLIIFHHKYRYHLSSeETGPILVHCGAGVGRTGTFIAID
|.| |.||.|| |||..||. |. |. | .. . . . | |...|| ||||||| |.||
...................................kgddartvaqfhftewPdkdvpkhtssllkfikevkadfGq.ythpliihcsagvgrtgvvisid
SLMDQMMMEGVVDVYGFVAQMRTQRNFMVQTHEQYAFIYDVLRDASLCGITEIPSQEIASSLLVLR
|.. . .|||. ||...| .| .||||.||||||| . . | | || .. | |
svvahakktrmvdvfnfvtnirrkrpymvqtkeqyafiygavledllwrntlipvvhftdhlqdls
|
|||||||||
subfamily_PTPN1_pd | Subfamily PTPN1 | 14-254 | 4.6e-56 | 184.7 | In-house | 25-267 (290) | alignment | ||
Range on Protein: 14-254
Range on HMM: 25-267/290.0
EAAQTPYNKTKNRYPNILPYDHSRVVLRARKDshgsDYINANFVDGYGCPQKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTEHKLRSDCERYWPED
..|..| |...||| .. ||||||..|. . |||||..|. ..|| .||||..|.. ||...||. . ..||| | . | .|||..
reaklpenrnlnryrdvspydhsrikleradn....dyinaslveleeakrsyiltqGPlpntvdhfWqmvWeqkskavvmlnkvvekeqikcaqywPqg
GHQEYGDVAVSVVDVTHMTDWTVRTFLV-WVRLHP-ECMDKREVTQFQFTAWPDQGVPENTAPLIIFHHKYRYHLS-SEETGPILVHCGAGVGRTGTFIA
... . . . |. .. . ... | ...|. .. . ||...| .|.||| |||| | .. | .| | | |.. || ..|| ||.||.|||.
eeekellledtklkvkliseerksyytvrllelenlktqetreilhfhyttwpdfgvpespaaflkflfkvresGslssdvGpavihcsaGiGrsGtfcl
IDSLMDQMMMEGV---VDVYGFVAQMRTQRNFMVQTHEQYAFIYDVL
.|... .. .. ||. . ..| .| ..|| .| | | .
vdtclvliekkddlssvdikkvllelrkyrlGliqtadqlrfsylai
|
|||||||||
subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 14-251 | 1.3e-55 | 183.2 | In-house | 1-234 (239) | alignment | ||
Range on Protein: 14-251
Range on HMM: 1-234/239.0
EAAQTPYNKTKNRYPNILPYDHSRVVLRARKDSHGSDYINANFVDGY-GCPQKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTEHKLRSDCERYWPe
|||. ||.|||| ||. |||||||| . ||||||... | | |. |||.|| .. . ||||..|.. |||| . | .|||
eaakkrvnkaknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywp.
DGHQEYGDVAVSVVDVTHMTDWTVRTFLVWVRlhpECMDKREVTQFQFTAWPDQGVPENTAPLIIFHHKYRyHLSSEETGPILVHCGAGVGRTGTFIAID
| .| .. |.. ..|. .|||.. ..| | |..|| |||.|||. .. .. ...| . | . | ..|| |||||||.|. ||
dstskycnlrvtlrktevfadyiirtfvmsqv...gqteeryvyqyhftvwpdkgvpqyatavlglrrkit.kdslpgarpwvihcsagvgrtgaflvid
SLMDQMMMEGVVDVYGFVAQMRTQRNFMVQTHEQYAFIY
... | . ||.. .| .| .| .|||| ||| ||.
amlrqakkqktvdifnyvkairedrphmvqtseqyvfih
|
|||||||||
subfamily_Cele-PTP-13_pd | Subfamily Cele-PTP-13 | 14-258 | 2e-37 | 123.4 | In-house | 30-269 (281) | alignment | ||
Range on Protein: 14-258
Range on HMM: 30-269/281.0
EAAQTPYNKTKNRYPNILPYDHSRVVLRA-RKDSHGSDYINANFVDGYGCPQKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTEHKLRSDCERYWPE
. . | |. |||| || | ||| |. . .||| ||.. . || .||| || ||||.||.. |.|||| . | | |.|
tvfnqpvnnkknrylnipcldisrvqlkvkmpnknstdyihanyirspflkrgyiltqgpkketradfwrmiwqenttaivmlcqfletnrekcaeyfpr
DGHQEYGDVAVSVvdvtHMTDWTVRTFLVWVRLHPEC-MDKREVTQFQFTAWPDQGVPENTAPLIIFHHKYRyhlsSEETgPILVHCGAGVGRTGTFIAI
. | .|| | || || || . | .|.. . ||| ||| . .. .| | . | | ..|| |||||.||..|.
nahcclqfdklsv....syedstvnkslvttrlnlsyegetrlithwlwkewpdwqvpessevmlkilrkir....arst.ppvihcsagvgrsgtlmav
DSLMDQMMME-GVVDVYGFVAQMR-TQRNFMVQTHEQYAFIYDVLRDAS
. .. . . |. |...| | | ||| .|| .|. || |
eialqsihshftlpdikqivshlrvtgraasvqtlqqymliwkvlldfg
|
|||||||||
subfamily_Sponge-PTP4_pd | Subfamily Sponge-PTP4 | 14-171 | 1.3e-18 | 61.5 | In-house | 89-238 (244) | alignment | ||
Range on Protein: 14-171
Range on HMM: 89-238/244.0
EAAQTPYNKTKNRYPNILPYDHSRVVLraRKDSHGSDYINANFVDGYGCPQKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTEHKlrsdcERYWPED
. | | | ||| ||.| .|| | | | | |||| || | .|| .| ||..| |||... |. .|.|| | . . |||.
kdafnpnnswknregaglpfdfnrvpl..skgsmgntyinasfvgclgrtaeyiltqhpladtsmdfwkmmlerhvnvlvvlgsveee.....deywpds
GHQEY--GDVAVSVVDVTHMTDWTVRTFLVWVRLHpecMDKREVTQFQFTAWPDQGVPEN
|. |..|.. | . . . . . .. .| || . || .| |
eplewyeeditvtltdrdefknikasnleiesdmn...eshqaltmfqisnwpsdgttpn
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 14-60 | 1.5e-10 | 35.0 | In-house | 40-86 (440) | alignment | ||
Range on Protein: 14-60
Range on HMM: 40-86/440.0
EAAQTPYNKTKNRYPNILPYDHSRVVLRARKDSHGSDYINANFVDGY
. | | || |||| ||| ||||||.| | |||||| ...|
diaslpnnkvknryrnilaydhsrvmleevkgvpdsdyinasyingi
|
|||||||||
subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 15-280 | 2.9e-73 | 241.7 | In-house | 37-298 (515) | alignment | ||
Range on Protein: 15-280
Range on HMM: 37-298/515.0
AAQTPYNKTKNRYPNILPYDHSRVVLRARKDSHGSDYINANFVDGYGCPQKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTEHKLRSDCERYWPE--
|| | .|||| |||||| .|| | .|. |||.|| .. .. . . |||.|||. ...|||||.... |||.|. . .. .. | .|||.
vaqeeinfkknryknilPydsvrvklevindnPhsdyfnasyipsfdndkayiasqgPnkasvddfWrlvlqenvttiamvtklkegdkikcgkyWPdkp
DGHQEYGDVAVSVVDVTHMTDWTVRTFLVwVRlhpeCMDKREVTQFQFTAWPDQGVPENTAPLIIFHHKYRYHLsSEETGPILVHCGAGVGRTGTFIAID
..| . |..| . |. . |.. | .. | | ||||.|| |||.|||..| |. . .. . .. | |...|| ||||||| .|.||
gdsvkfGsikvelvsleactggikrkltv.lk....gddsrtvtqfhfteWPdkGvpkhtssllklikevkadh.gqythpliihcsaGvGrtGvvisid
SLMDQMMMEGVVDVYGFVAQMRTQRNFMVQTHEQYAFIYDVLRDASLCGITEIPSQEIASSLLVLRDN
| . .. .|||. || ..| .| ..|||.|||||||..... | | || .. | |
svvahakttrmvdvfnfvtnirqkrpylvqtqeqyafiygavledllwrntlipvihftdhlqdlhss
|
|||||||||
subfamily_Sponge-PTP5_pd | Subfamily Sponge-PTP5 | 15-270 | 6e-60 | 197.5 | In-house | 27-278 (283) | alignment | ||
Range on Protein: 15-270
Range on HMM: 27-278/283.0
AAQTPYNKTKNRYPNILPYDHSRVVLRARKDshgsDYINANFVD---GYGCPQKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTEHKLRSDCERYWP
| . ||.|||. .|.|.| || |.. ||||| |. | .|||.||.|| .|..|||...... |.|||| || | .|||
iasadenkrknrnqeivpadqwrvelksesr....dyinavfipvsksykqdkkyiiaqsPldrtvvdfWkmvfdekitaivmltklqedlrikCsqyWP
EDGHQEYGDVAVSVVDVTHMTDWTVRTFLVWVRlhPECMDKREVTQFQFTAWPDQGVPENTAPLIIFhHKYRYHLSSEETGPILVHCGAGVGRTGTFIAI
..| ..||. .|.. . | .... .|. | . .. .. .|. | . | |. | | . .. |||.||| .|.|||..|||.
krGsedyGeftvtlrkettsnsfiikelllrvn..ssakstlllahyqvidWleygeqaiinslvkf.nkvislqteskkgPivvhCstgiGrtavfiaa
DSLMDQMMMEGVVDVYGFVAQMRTQRNFMVQTHEQYAFIYDVLRDASLCGITEIPSQEI
. ..... | ||||. | || || .||| .|| ..... . .||| |.| ..
sasvkdaltesvvdvfavvkimreqrmmavqtldqyklvhelvleqalcgdtqiaavdl
|
|||||||||
subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 15-252 | 3.2e-55 | 181.9 | In-house | 1-234 (239) | alignment | ||
Range on Protein: 15-252
Range on HMM: 1-234/239.0
AAQTPYNKTKNRYPNILPYDHSRVVLRARKDSHGSDYINANFVDGY-GCPQKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTEHKLRSDCERYWPeD
||. ||.|||| ||. |||||||| . ||||||... | | |. |||.|| .. . ||||..|.. |||| . | .||| |
aakkrvnkaknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywp.d
GHQEYGDVAVSVVDVTHMTDWTVRTFLVWVRlhpECMDKREVTQFQFTAWPDQGVPENTAPLIIFHHKYRyHLSSEETGPILVHCGAGVGRTGTFIAIDS
.| .. |.. ..|. .|||.. ..| | |..|| |||.|||. .. .. ...| . | . | ..|| |||||||.|. ||.
stskycnlrvtlrktevfadyiirtfvmsqv...gqteeryvyqyhftvwpdkgvpqyatavlglrrkit.kdslpgarpwvihcsagvgrtgaflvida
LMDQMMMEGVVDVYGFVAQMRTQRNFMVQTHEQYAFIYD
.. | . ||.. .| .| .| .|||| ||| ||.
mlrqakkqktvdifnyvkairedrphmvqtseqyvfihl
|
|||||||||
subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 16-260 | 4.1e-78 | 257.0 | In-house | 4-244 (250) | alignment | ||
Range on Protein: 16-260
Range on HMM: 4-244/250.0
AQTPYNKTKNRYPNILPYDHSRVVLRARKDSHGSDYINANFVDGYGCPQKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTEHKLRSdCERYWPEDGH
|. | || |||| .|...|.||||| | . |||||| |..|| . .||.||||..||.||||...|. .||||| . . . . ...||| ..
akkpqnkeknryadiialdssrvvLekekgdkesdyinasflhgyderkafiatqgPlqatiedfWrmvleeksgtivmLtnLkesekt.yhqywPveka
QEYGDVAVSVVDVTHMTDWTVRTFLVWVRlhpECMDKREVTQFQFTAWPDQGVPENTAPLIIFHHKYRYHLSSEETGPILVHCGAGVGRTGTFIAIDSLM
..|||| ||. . ...|.|.|.. . . . |.| | |..|..|||.||||.. . . .| . ...|..|.| |||||.|.|||||...
ekyGdvtvsllskeefadytkrklklska...kkaderivrqlhfvvWPdkgvPevatavLellkkvqasqqqagnaPvivqCsaGvgrsGafiaidavl
DQMMMEGVVDVYGFVAQMRTQRNFMVQTHEQYAFIYDVLRDASLC
... | ||||. .. ..|..| .|...||| |.| .. | .
erlkkekvvdvfkvikvlrkdrphavesleqyvfvyeiilkalds
|
|||||||||
subfamily_PTPN5_RR_pd | Subfamily PTPN5_RR | 16-254 | 7.1e-71 | 233.5 | In-house | 23-264 (274) | alignment | ||
Range on Protein: 16-254
Range on HMM: 23-264/274.0
AQTPYNKTKNRYPNILPYDHSRVVLRAR-KDSHGSDYINANFVDGYGCPQK-YIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTEHKLRSDCERYWPED
. . ..||||| .||| ..|||.|... ... |.|||||.. ||. .| |.|.||||..|..||||.|... .. |||| . . . .. |..|.|..
ldvfgsqtknryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntvadfWrmiyqeevqvivmltklkeaneqkCavyfPda
GHQ----EYGDVAVSVVDVTHMTDWTVRTFLVWvrlhpECMDKREVTQFQFTAWPDQGVPENTAPLIIFHHKYRY--HLSSEETGPILVHCGAGVGRTGT
. .|||| . |..... |..||.... .. ..|.|. . .|.|||. .|... .|. . .. . . ......|..||| ||.||||
edyeiserygdveikvekiverndysvrklvlk.....ylerersvkhywytdWPdhksPddantlldlvleveesreeenaklapvvvhCsaGiGrtGc
FIAIDSLMDQMMMEGVVDVYGFVAQMRTQRNFMVQTHEQYAFIYDVL
||||. . |. |.|||| . |...| .| ||||.||| .|. .|
fiaisiavrqlreeivvdvlkivcnlrldrGGmvqtseqyelihral
|
|||||||||
subfamily_Sponge-PTP6_pd | Subfamily Sponge-PTP6 | 17-256 | 1.1e-62 | 207.0 | In-house | 44-277 (439) | alignment | ||
Range on Protein: 17-256
Range on HMM: 44-277/439.0
QTPYNKTKNRYPNILPYDHSRVVLRARKDSHGSDYINANFVDGYGCPQKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTEHKLRsdcerYWPEDGHQ
|..||||| .. ..||.||.|. | |||||...|| .. |||.||| || .|||||..|| ..||||| . . . ||| |..
aqeydqtknrykdvgafdhtrvtlqeipgvphshyinanyikGyyddklyiatqgpkkettddfwrlviekktvtivmltnlvesyk.....ywpsdaev
EYGDVAVSVVDVTHMTDWTVRTFLVWVRLHpECMDKREVTQFQFTAWPDQGVPENTAPLIIFHHKYRYHLSSEETGPILVHCGAGVGRTGTFIAIDSLMD
|||.|| | . ....| | |. . . .| | ||...||||. || ... .. | . .||.||..||| |||||||| ||.| ..
cygdiavrvdrnielpnyvirgfkvfnerd.ttekertvlqfhyiawpdknvpaqashvldflrainsandkeeygpvvvhcsagvGrtGtiialdiale
QMMMEGVVDVYGFVAQMRTQRNFMVQTHEQYAFIYDVLRD
|. .| ||. | | .| ||. |||. || |||. . .
qlklenkvdikgivkvlrkqrkqmvqalcqyvfiynavle
|
|||||||||
subfamily_Sponge-PTP-2_pd | Subfamily Sponge-PTP-2 | 17-174 | 6.9e-12 | 38.6 | In-house | 23-160 (169) | alignment | ||
Range on Protein: 17-174
Range on HMM: 23-160/169.0
QTPYNKTKNRYPNILPYDHSRVVLRARKDSHGSDYINAnfvdgygcpqkyiaaqgpltetikdfwRLIWEKGCTTIVMLGDTEHKlrsdcERYWPEDGH-
. |.|||| | | || |. . ||||||| |.||| . ||.||||. | . .|||
eltcnetknrpagplapshtrvklqrvmedlgsdyina...........................rmiwetnasvivvlgdtddk.....nnfwpekedy
Q---------EYGDVAVSVVDVTHMT-DWTVRTFLVWVRLHPECMDKR-EVTQFQFTAWPDQGVPENTAP
| | | | |. . | | . .| | ... .....||..|||..
qlhpavilgewytdslyvrtdkvhantsgveglfevsmvihsydddvteklsllhystwpqngvpqspvh
|
|||||||||
subfamily_Sponge-PTP2_pd | Subfamily Sponge-PTP2 | 17-172 | 9.5e-12 | 38.1 | In-house | 22-157 (169) | alignment | ||
Range on Protein: 17-172
Range on HMM: 22-157/169.0
QTPYNKTKNRYPNILPYDHSRVVLRARKDSHGSDYINAnfvdgygcpqkyiaaqgpltetikdfwRLIWEKGCTTIVMLGDTEHKlrsdcERYWPEDGHQ
. |.|||| | | || |. . ||||||| |.||| . ||.||||. | . .|||
eltcnetknrpagplapshtrvklqrvmedlgsdyina...........................rmiwetnasvivvlGdtddk.....nnfwpekedy
-E---------YGDVAVSVVDVTH-MTDWTVRTFLVWVRLHPEcmdKREVTQ----FQFTAWPDQGVPENT
| | | | | | | . .| ...||. .....||..|||..
qlhpavilGewytdslyvrtdkvhpntsgveglfevslvihsy...dddvteqlsllhystwpqngvpqsp
|
|||||||||
subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 18-261 | 1.9e-69 | 228.8 | In-house | 44-281 (287) | alignment | ||
Range on Protein: 18-261
Range on HMM: 44-281/287.0
TPYNKTKNRYPNILPYDHSRVVLRarkdSHGSDYINANFVDGYGCPQKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTEHKLRSDCERYWPEDGHQE
.. || |||. .||..| ||.|. . ||||| |.||| ...|.|..|...|...||.||... |.|||| . . . .. | .||||.
asqnkdknRltqilvpdnyrvllk....gehpdyinavfidgykekkafiiaesPmfntarnfWkliddrnvtaivmlcqekendeevcyqyWpeeksvv
YGDVAVSVVDVTHMTDWTVRTFLVwvRLHPECMDKREVTQFQFTAWPDQG-VPENTAPLIIFHHKYRYHLSSEEtGPILVHCGAGVGRTGTFIAIDSLMD
.|. ...... ........|.. | . . . ||..|.|.|.|.|...| |.| . |......|. . . . ..|.||| ..|||...|.|.. ..
lGeyniellneevnagyierklev..knknkagdkqqvkqyqitnWdstgkvtepqtillvieemyktqrkrgn.tsivvhCsdtvGrsamfcaaattin
QMMMEGVVDVYGFVAQMRTQRNFMVQTHEQYAFIYDVLRDASLCG
. |||.||. . ..| |. .||| ||| ||.|.. ..
kckteGviDvfqvlksqriqkpgsvqtveqykfindivleyldsf
|
|||||||||
subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 19-267 | 1.8e-70 | 232.4 | In-house | 49-293 (297) | alignment | ||
Range on Protein: 19-267
Range on HMM: 49-293/297.0
PYNKTKNRYPNILPYDHSRVVLRARKDSHGSDYINANFVDGYGCpqKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTEHKLRsDCERYWPEDGHQEY
| |.|| |||||| ||| |. . |. |||.|| || |. ..|. | | .|..|||...... .||||| | ... . | |||...| ...
kvnfeksRYkniLPydssRvkLaivnddpdsDyvnasfvkgnkh..rlittqmPmkatvadfWamvldeqvstivmlnddnerdk.kcaryWsdkgvttf
GDVAVSVVDVTHMTDWTVRTFLVWvrlHPECMDKREVTQFQFTAWPDQGVPE--NTAPLIIFHHKYRYHLSSEETGPILVHCGAGVGRTGTFIAIDSLMD
|||.| . |.. . |.. | . . .| | |.||. |||. |.. ... |. . . | . |... ||.|||| ||||||| ...||| .
GdvsvvllsvsereGfikrelevt...kgkakarrvvkqyqfveWPdkaverkdsassllklisevrkdfsqnaegPllvhclaGvGrtgvlltidsvva
QMMMEGVVDVYGFVAQMRTQRNFMVQTHEQYAFIYDVLRDASLCGITEIPS
.. | ||..|.| ..| .| ..|||.|||.|.| .. .| |. |.|..
eakrekevdifglvkklrqerpylvqtkeqykfvyvavleallsedtriqa
|
|||||||||
subfamily_PTPN23_pd | Subfamily PTPN23 | 19-254 | 5e-57 | 187.9 | In-house | 41-277 (288) | alignment | ||
Range on Protein: 19-254
Range on HMM: 41-277/288.0
PYNKTKNRYPNILPYDHSRVVLRARKDshgsDYINANFVDGY--GCPQkYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTEHKLRSDCERYWPEDG--
. .|||. .||||||.||.|| || ||||| || . |||. .||.|.|| .|. |||....|. .|||| . | . . ..||||||
klyseknrsrdilPyDhnRvklrgskD....DYinAsfvkdlspgcPd.fiatqaPlqstlnDFWlmvyeqkssviVmllskeelgkpkvdrYwPedkge
HQEYGDVAVSVVDVTHMTDWTVRTFLVWVRlhpECMDKREVTQFQFTAWPDQGVPENTAPLIIFHHKYRYHL--S-SEETGPILVHCGAGVGRTGTFIAI
...||. |.. .|... . |.. . .. . ...|. |.|.||. |||. |. | .. . .. . |..||| |||||||.| .
tvkfgdlsvtlksvretethvervlkletl...dadavksvshlqltsWpelGvPasPetllqfldevesayeavqrksktPlvvhCsaGvgRtgvfalv
DSLMDQM-MMEGVVDVYGFVAQMRTQRNFMVQTHEQYAFIYDV-L
. . .. .|..|. | ..|.|| ||||..||. | |.. |
yaavrelekgnglldiiqvvsrlreqRrfmvqekeqlkfsyeavl
|
|||||||||
subfamily_Sponge-PTP9_pd | Subfamily Sponge-PTP9 | 19-255 | 1.2e-56 | 186.6 | In-house | 38-290 (301) | alignment | ||
Range on Protein: 19-255
Range on HMM: 38-290/301.0
PYNKTKNRYPNILPYDHSRVVLRARK--DSHGSDYINANFVDGYGCPQKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTEHKLRSDCERYWPE--DG
||. ||. || .||. |..|. . |.. .||||...||| .|.||||||. .|..|||||||.. ..|||. ... . .| ||.|||.
eenkalnrfknitvyddnriilkpkpnldlcqreyinasyidgysekkkfiaaqgpmkktlvdfWrliwqekpvsivmvtnlkegtkskceqywpnseae
HQEYGDVAVSVVDVTHMTDWTVRTFLVWVRLHPE-----------C-MDKREVTQFQFTAWPDQGV-PENTAPLIIFHHKYrYHLSSEETGPILVHCGAG
..|.| . | .|. . . |...| . | .. . .. ..|.|.| | ||..|| .| | . . . . . ||..||| ..
seefgpftvtlvneqvyPdfvirqlnvkiqdgsnngyierkfkvksdksswdvlqlqvtdWpqdGvvreprtvLqviddvi.hrqqkigggpvvVHCSdt
VGRTGTFIAIDSLMDQMMMEGVVDVYGFVAQMRTQRNFMVQTHEQYAFIYDVLR
|.|.|...... ..| ||||||.. . .| .. .|.| ||| .||||.
VsrsGvYcsvsiglEQckaegVVdvfqvtkavrrskpgaVtTLeqytsiydvid
|
|||||||||
subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 19-257 | 5e-43 | 142.0 | In-house | 31-258 (267) | alignment | ||
Range on Protein: 19-257
Range on HMM: 31-258/267.0
PYNKTKNRYPNILPYDHSRVVLRARKDShgsdYINANFVDGYGCPQKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTehkLRSDCERYWPED--GHQ
|. .||. . ||||..||.|| ... |||| .|.|| ...|. |.|| || ||. .| ......||.| . . ..|| .
eknqernrlddnlpyddtrvilrtkeee....yinasyvegyktknafivtqdplkntitdfltvihdqkvpvivlltkv...ftdnirlfwPPkmgqak
EYGDVAVSVVDVTHMTDWTVRTFLvwVRLHPEcmDKREVTQFQFTAWPDQgvpENTAPLI--IFHHKYRYHLSsEETGPILVHCGAGVGRTGTFIAIDSL
.| |..| |. . |. .... | ..|| . . | . | | . .| . .| . |..|.| .||||.|||. |||
kyqdltvehslekeendyqiitle..lkfkne..sahnvtlyyykkwnin...tnnkpylkplfgilaknqle.ngnrPlvvacsdGvGrsGtflvidsq
MDQMMMEGVVDVYGFVAQMRTQRNFMVQTHEQYAFIYDVLRDA
.... |||.|.. |. ..| || .|.| |.| .|...| .
leraktegvsdifdflrkirsqriglvdtkeryiyihellaey
|
|||||||||
subfamily_Cele-PTP-18_pd | Subfamily Cele-PTP-18 | 19-254 | 2.1e-35 | 116.9 | In-house | 46-283 (305) | alignment | ||
Range on Protein: 19-254
Range on HMM: 46-283/305.0
PYNKTKNRYPNILPYDHSRVVLrarKDSHGSDYINANFVDGYGCPQKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTEHKLRSDCERYWPEDGHQ--
.. |||| .. |. || | . . .|| ||.| |...| .| || .| ||| . ... .| || . | | |.. . ..
aqeagknrykdvgcldnnrvkl...egpwpheyihanyvstptnpkrfictqaplektcadfwymclqdkveaifmlcnllekgakkcleyfaskdkdvl
---EYGD-VAV---SVVDVTHMTDWTVRTFLVWVRLHPECMDKREVTQFQFTAWPDQGVPENTAPLIIFHHKYRyhlssEETGPILVHCGAGVGRTGTFI
| |. ..| | | . .| . . . ..| ||.. . |||.||| .. . .| | ||| ||| ||.||||. .
efeekgqkisvkfessvtlkfrkdakakvtetvlviegpgekarkvthyhwidwpdrgvpaadlailellekar.....pskgpivvhcsagigrtgsvv
AIDSLMDQMMMEGVVD-VYGFVAQMRTQRNFMVQTHEQYAFIYDVL
.. ..||.. ... . ..| ||| .|| .|| |...|.
mleyildqllagqiiedtdkilqkireqrnnsiqtdaqylfvhqvi
|
|||||||||
subfamily_Cele-PTP-19_pd | Subfamily Cele-PTP-19 | 19-248 | 3.3e-32 | 106.4 | In-house | 48-271 (301) | alignment | ||
Range on Protein: 19-248
Range on HMM: 48-271/301.0
PYNKTKNRYPNIlPYDHSRVVlRARKDSHGsDYINANFVDGYGCPQKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTEHKLRSDCERYWPEDGHQE-
.| |.|||.. | . | | . .| . | ||... | |...||.||||..| .||| .. .||||| . || . || | | . ...
ylpkdkhryptv.PckPstav.evivdGkr.vPihanwiptsGhphrfiatqgPlkntsedfwamlvqydvekivmlgqkvekleekceeylpvkisekl
-YGDVAVSVVDVTHMTDWTVRTFLVWVRLHPECMDKREVTQFQFTAWPDQGVPENTAPLiiFHHkyrYHLSSEETGPILVHCGAGVGRTGTFIAIDSLMD
| . ... .. . . . |. . .. | || .|.. |.|.|||. | | |. .| . ||.||| ||.||. .||. . |
digrfkikiknkelilnkkiskrtlevedstgkfatrtvthyqysewtdrgvPkshael..fdl...melvkksekPivvhcsaGiGrsvafigteylar
QMMMEGVVDVYGFVAQMRTQRNFMVQTHEQYA
.. . ... ....| .| |||..|
eveadptieltealkhlrehrwngvqtnsqly
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 19-178 | 3e-28 | 93.4 | In-house | 26-186 (319) | alignment | ||
Range on Protein: 19-178
Range on HMM: 26-186/319.0
PYNKTKNRYPNILPYDHSRVVLRARKDSHGSDYINANFVDGYG-CPQKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTEHKLRSDCERYWPE----D
. | |.|. |..| ..||||. | . |..|..| || .| ||||| .| .. ||||..||. .|| | | . | .|.| |
vtskdksrvinvvPlPetrvvlqrigdddkdeyldasyvrGyddapnsyiaaqvsledsssdfwrtvweqqsrvivqltdlselGikvcaeylPtketld
GHQEYGDVAVSVVDVTHMTDWTVRTFLVwVRLhpECMDKREVTQFQFtAWPDQGVPENTAPLIIF
... |||. |.. . . . |.|. |. . ||.| . . |.. .|| . |.||
ntslyGdilvtlkgrevkdryaistlll.krv..dkeesrelthywy.kwleaevPaeeaaliam
|
|||||||||
subfamily_Cele-PTP-16_pd | Subfamily Cele-PTP-16 | 19-257 | 3.6e-15 | 50.4 | In-house | 45-278 (303) | alignment | ||
Range on Protein: 19-257
Range on HMM: 45-278/303.0
PYNKTKNRYPNILPYDHSRVVLrarKDshgSDYINANFVDgYGCPQKYIAAQGPLTETIKDFWRLIWEKGCTT-IVMLGDTEHKLRSDcERYWP-EDGHQ
| |||. ... |||.| | | | || |.... . .| | .| ||. | |||..| |. ...| |.|.. . .| ..
vknmdknrfvdvicldhskvkl...sd...ssyihasyle.ldsskkailtqlplshtaadfwqmiieqkvkcvlllltdseydklgg.dsvfprnqdfl
EYGDVAVSVVDV---THMTDWTVRTFLVwvrlhPECMDKREVTQFQFTAWPDQGVPENTAPLII---FHHKYRYHLSSeETGPILVHCGAGVGRTGTFIA
.. . .. | . . |... | . | . .. ||| . .| ...| .. . . | .. | . .|.||.|||
kfeersirvgefkrvelgdgwvlkvlsv.....sngdyksflhvhhykawphnsipsdgspkfvkqiwqlqsvlrkys.dstptvymslsgcgragtfal
IDSL-MDQMMMEGVVDVYGFVAQMRTQRNFMVQTHEQYAFIYDVLRDA
... . . .|. . ..| | || |....| .| .
fetahlslhseqasldlvkclenvrngrlhavqnlsqfsvvytllaeh
|
|||||||||
subfamily_CG7180_pd | Subfamily CG7180 | 20-262 | 2.2e-66 | 218.5 | In-house | 41-294 (296) | alignment | ||
Range on Protein: 20-262
Range on HMM: 41-294/296.0
YNKTKNRYPNILPYDHSRVVLRARKDSHGSDYINANFVDGYGCPQKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTEHKLRsDCERYWPEDGHQEYG
|. |||.....|||. ||||. . . |||||| .||.. ...|| ..| .||...||||...... ..|.| .| . . |||......||
enreknrdvkvvPyDynRvvLekldGeeksdYinavyvdsflkkkeyivteapkketvdefWrlvydeeisavvvLtktfdfak.mypsywpnkskeqyg
DVAVSVVDVTHMTDWTVRTFLVWVR-------LHPECMDKREVTQFQFTAWPD-QGVPENTAPLIIFHHKYRYHLSSE----ETGPILVHCGAGVGRTGT
.. | .| . .... . ||| . . ... ...| |..||.| |. . || |. || . .. | |.||..|.. |..|.|
eifveiveekqyanlkirtfkltkkivalteqekqvkaetRivklfqlteWeledkvPlstnalielrrrvrlwrekvdedpeegPvvvvssdGasRsGv
FIAIDSLMDQMMMEGVVDVYGFVAQMRTQRNFMVQTHEQYAFIYDVLRDASLCGI
..||| .... |. |||...| ..| .|. .|.. |.| .||||| .| ||.
ylaidanlelvekeeevdvFeavktlrrsRpqLvenveeYkyiYdvlleavlcnk
|
|||||||||
subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 20-253 | 3.8e-66 | 217.7 | In-house | 2-234 (237) | alignment | ||
Range on Protein: 20-253
Range on HMM: 2-234/237.0
YNKTKNRYPNILPYDHSRVVLRARKDShgSDYINANFVDGY-GCPQKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTEHKLRSDCERYWPE-DGHQE
|| |||| || ||||||||. . ||||||....|. | |.||||||||| . .|||...|.. |. |||| . . | .|||. | .
enkiknrygnivaydhsrvvlkgagsg..sdyinatylkgfdgtpkkyiaaqgplesscddfwqmvwqekcsvivmltgliegnelkchkywpstdqpaa
YGDVAVSVVDVTHMTDWTVRTFLVWVRLHPEcmDKREVTQFQFTAWPDQGVPENTAPLIIFHHKYRYHLSS-EETGPILVHCGAGVGRTGTFIAIDSLMD
|| ..||. ...|.|||..|. .||. . . | . |.|||.|||.|||..|| |. | .. . |.|| ..|| ||||||| |. ||...
ygvltvslkkkeefsdytvrslllskrltlk..evrlihqyqftswpdrgvpqqtaallrfrkniinrsphvsesgpwiihcsagvgrtgiflvidamlr
QMMMEGVVDVYGFVAQMRTQRNFMVQTHEQYAFIYDV
| . |||.| .| . .| ...||..|| ||...
qakekkvvdiynyvysieedrpyiiqtkdqyvfihqt
|
|||||||||
subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 20-255 | 7.2e-38 | 124.9 | In-house | 53-280 (290) | alignment | ||
Range on Protein: 20-255
Range on HMM: 53-280/290.0
YNK--TKNRYPNILPYDHSRVVLrarKDSHGSDYINANFVDGYGcpQKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTEHKLRSDCERYWPEDGHQ-
| .|||| .. | .||.| || . ||. ||.|.| .| .||.|..|. |.||.. ... ..|||| . . .. ||.|.|| .
kntefkknrykdvvcndktrvil...kdGydGdyvhanyvkGlk..amfiltqGalkdtvidiwrmvlqekvaaivmlceliedGkakceqyypekeGev
-EYGDVAVSVVDVTHMTDWTVRTFLVwVRLHpECMDKREVTQFQFTAWPDQGVPENTAPLIIFHHKYRyhlssEETGPILVHCGAGVGRTGTFIAIDSLM
.|...| .. . ... | || . . . .. .|||. |. | |. . | . .||. ||| ||.||||||.||. .
ltfGeitvlcseeddkdaniikktls.vrdk.dsGkehklkhlkikswpdksvalstlallrtlrilr.....kasGpvvvhcsaGiGrtGtfvaievgl
dQMMMEG-VVDVYGFVAQMRTQRNFMVQTHEQYAFIYDVLR
|....| .|. . | .| | || || . ..|
.qilldGkeldlldlvralrnsrlnsvqvdiqylalveill
|
|||||||||
subfamily_Cele-PTP-17_pd | Subfamily Cele-PTP-17 | 20-95 | 7.6e-08 | 26.3 | In-house | 36-116 (347) | alignment | ||
Range on Protein: 20-95
Range on HMM: 36-116/347.0
YNKTKNRYPNILPYDHSRVVLRARKDSHG-----SDYINANFVDGYGCPQKYIAAQGPLTETIKDFWRLIWEKGCTTIVML
. .||| . | .|||| | . |||| . . ..|| .| || .|..|||... | .| .
kslsknrskdvklidatrvvlspeksknsraddvetyinashikfdnaskeyiltqyplpdtvrdfwkmvsvtkvtqvvti
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 21-254 | 1.6e-80 | 265.3 | Pfam-A | 1-233 (235) | alignment | ||
Range on Protein: 21-254
Range on HMM: 1-233/235.0
NKTKNRYPNILPYDHSRVVLraRKDSHGSDYINANFVDGYGCPQKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTEHKLRSDCERYWP--EDGHQEY
||.||||..|||||..|| | ..... |||||||.|.|| ..|.||.|||| .||.||||..|.. ...|||| . | | | |..||| |.. ..|
nkkknRykdilpydktrvkl..kgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeeslty
GDVAVSVV-DVT-HMTDWTVRTFLVWVRLHPEcmDKREVTQFQFTAWPDQGVPENTAPLIIFHHKYRYHLsSEETGPILVHCGAGVGRTGTFIAIDSLMD
||. | .. ... .....|.|.. . . ... .||||.|...|.|||.||||.. .|. . .| . . ....||..||| |||||||||.|.| |..
gdikvelkekekedekeytlrklelkkkkees..ekrevkqlhytnWpdhgvpespkslldlirkveksk.eaksgpvvVhCsaGvgRtgtfvaldille
QMMMEGVVDVYGFVAQMRTQRNFMVQTHEQYAFIYDVL
|. |. |||. .| ..|.||. |||. |||.|.|...
qleaeeevdvlqivkelRkqRpgmvqsleqYiflykai
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 21-254 | 1.6e-80 | 265.3 | In-house | 1-233 (235) | alignment | ||
Range on Protein: 21-254
Range on HMM: 1-233/235.0
NKTKNRYPNILPYDHSRVVLraRKDSHGSDYINANFVDGYGCPQKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTEHKLRSDCERYWP--EDGHQEY
||.||||..|||||..|| | ..... |||||||.|.|| ..|.||.|||| .||.||||..|.. ...|||| . | | | |..||| |.. ..|
nkkknRykdilpydktrvkl..kgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeeslty
GDVAVSVV-DVT-HMTDWTVRTFLVWVRLHPEcmDKREVTQFQFTAWPDQGVPENTAPLIIFHHKYRYHLsSEETGPILVHCGAGVGRTGTFIAIDSLMD
||. | .. ... .....|.|.. . . ... .||||.|...|.|||.||||.. .|. . .| . . ....||..||| |||||||||.|.| |..
gdikvelkekekedekeytlrklelkkkkees..ekrevkqlhytnWpdhgvpespkslldlirkveksk.eaksgpvvVhCsaGvgRtgtfvaldille
QMMMEGVVDVYGFVAQMRTQRNFMVQTHEQYAFIYDVL
|. |. |||. .| ..|.||. |||. |||.|.|...
qleaeeevdvlqivkelRkqRpgmvqsleqYiflykai
|
|||||||||
subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 21-254 | 8.3e-63 | 206.9 | In-house | 20-260 (270) | alignment | ||
Range on Protein: 21-254
Range on HMM: 20-260/270.0
NKTKNRYPNILPYDHSRVVLRARKDSHGSDYINANFVDGY-GCPQKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTEHKLRSDCERYWPEDGHQeYG
.|. ||| .||| ..||.| .. . . |||||.| |. | ..|||||.||| |.|.|||.|||. |.|||. . | | |. ||||||.. ..
gkklnRyadiLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpaepke.kv
DVAVSVVDVTHMTDWTVRTFLV-WVRLHpECMDKREVTQFQFTAWPDQGVPENTA------PLIIFHHKYRYHLSSEET-GPILVHCGAGVGRTGTFIAI
... . |. ... . ... .||. | ..|... |....|||.|||... |. .. | . .. . .|.|||| ||||||||.||.
kledgkikvlalseekeegyiltrlrle.ekgeerrlvHfwyntWpdhgvpreedsslstdqllkmlravrrsekeldkaePllvHcsaGvgRtGtlial
DSLMDQMMMEGVVDVYGFVAQMRTQRNFMVQTHEQYAFIYDVL
| . . ... ||| ....| .| .||. |||.|.| ..
DiavrlLeetkkvdvlaiieelRkdRmalvqhpeqyeflykav
|
|||||||||
0041856 | (Phosphotyrosine protein) phosphatases II | 21-266 | 1.6e-53 | 176.3 | In-house | 1-179 (182) | alignment | ||
Range on Protein: 21-266
Range on HMM: 1-179/182.0
NKTKNRYPNILPYDHSRvvlrarkdshGSDYINANFVDGYGCPQKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGdtehklrsdCERYWPEDGhqeygd
|..||||..|||||||| ..||||||...|. ....||.|||| .|. ||.|...| |.||||.| .|.||||.
nldknrysdilpydhsr..........dldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlt.........eelywpell......
vavsvvdvthmtdwtvrtflvwvrlhpecmdKREVTQFQFTAWPDQGVPEnTAPLIIFHHKYRYhlsseETGPILVHCGAGVGRTGTFIAIDslmdQ---
.|...|.... ||| |||. . |. | .. . | ||.|||| ||||||||..|..
...............................erlgiqylylpwpDhgvpd.ldelldfieevle.....eggpvlVHCsaGvgRtgtlvaay....lmkk
MmmeGvVDVYGFVAQMRTQRNFMVQTHEQYAFIYDVLRDASLCGITEIP
. | |... |...| .|. ||.| .|| |....|.. |...|...
l...g.vsleeavklvrsrRpgmvitpnqyfflqlallellllkktrpk
|
|||||||||
subfamily_Cele-PTP-8_pd | Subfamily Cele-PTP-8 | 21-254 | 3.2e-30 | 100.1 | In-house | 43-267 (288) | alignment | ||
Range on Protein: 21-254
Range on HMM: 43-267/288.0
NKTKNRYPNILPYDHSRVVLRarKDSHgsDYINANFVDGYGCPQKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTEHKLRSDCERYWPEDGHQ-EYG
| |..|| |. | .|| | |.. ||.|| | ... | || || ||. .|... |.. |||| . | . . |.| .
nptrdryenlprcditrvkls..ddpd..fyiaanvvssakykrrlicaqaPlngtieelWkmllesdveyivmlcellekGkeksaeyfPsklGekari
DVAVSVVDVTHmTDWTVRTFLVWVRLHPECMDKREVTQFQFTAWPDQGVPENTAPLIIFHHKYryhlsSEETGPILVHCGAGVGRTGTFIAIDSLMDQMM
.|| . . .| . .| . | .| | . . |.|.||||| . . . . . . ||.||. ||||||||.| | ....
grlctvvkkkr.adidklvkvsllriskegeekvivkilhlleWdddgvPenylsplrllevl.....kslqkPivvhssaGvGrtgtlililialeslr
MEGVVDVYGFVAQMRTQRNFMVQTHEQYAFIYDVL
.. . . ..|..| .| .|| || ... ..
lddflgirsllaklreerfkaiqtemqylyvhrcv
|
|||||||||
subfamily_Cele-PTP-4_pd | Subfamily Cele-PTP-4 | 21-253 | 8.7e-21 | 68.6 | In-house | 51-280 (302) | alignment | ||
Range on Protein: 21-253
Range on HMM: 51-280/302.0
NKTKNRYPNILPYDHSRVVLRARKDshgsDYINANFVDGYGCPQKYIAAQGPLTETI---KDFWRLIWEKGCTTIVMLGDTEHKLRsDCERYWP--EDGH
| ||. ... .|. .| | |..| .|.|| |. . .. | || | ... .|||..... ....|.| .| . . ..| . .
nlkknqsedvpildsnlvkleaepd....syvnaskvevPeltrsiilaQlpkvdsedsveeFWrmvfqekivsvvilvgeeelkk.tlselfpkksgdy
QEYGDVAVSVVDVTHMTDWTvRTFLVWVrLHPECMDKREVTQFQFTAWPDQGVPENTAPLIIFHHKYrYHLSSEETGPILVHCGAGVGRTGTFIAIDSLM
.|||.. | . | .. . . . . | | .| . .. .| |... ||.. | || .| ...... . .... |.|| |.|.. .
keygkmfvNnrkVekaeeek.tryviEv.lPegcsnsvlanvyvltnWkqkkvpvkyaeliktaakv.fakkikadentvivSknGaGRagafltlavav
DQMMMEGVVDVYGFVAQMRTQRNFMVQTHEQYAFIYDV
... . . . |...|.|| .|.. .||...| .
eklqkgkepnikeivksiRsqRpravdslkQyvslyia
|
|||||||||
subfamily_Cele-PTP-12_pd | Subfamily Cele-PTP-12 | 21-102 | 3.8e-12 | 40.3 | In-house | 34-114 (332) | alignment | ||
Range on Protein: 21-102
Range on HMM: 34-114/332.0
NKTKNRYPNILPYDHSRVVLrARKDSHgSDYINANFVDGYGCPQKYIAAQGPLTET-IKDFWRLIWEKGCTTIVMLGDTEHKL
| || | . .||||| | | .| . |. ||..|||| || || |. . |||.. |. . |...|| . |
nmdmnriphlycfdhsrvel.apqdgk.ddfynaswvdgyskksayifaqapfndhteyvfwrmvserkpsmilvfgdidekq
|
|||||||||
subfamily_Cele-PTP-11_pd | Subfamily Cele-PTP-11 | 22-252 | 2.4e-24 | 80.6 | In-house | 44-270 (312) | alignment | ||
Range on Protein: 22-252
Range on HMM: 44-270/312.0
KTKNRYPNILPYDHSRVVLRARKdshgSDYINANFVDGYGCPQKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTEHKLRSDCERYWP-------EDG
| |||||| .| | | . || |||| |......|||| .|. ||.| |.|.|..| . | .| .
kdlnrypniqcwdrgrftlagde....nfyihanfvkictkperfvctqgplentcthfwqlalslgstsiillcgfvedgsekcakyisdivgfvdled
HQEYGDVAVSVVDVTHMTD-WTVRTFLVWVRLhpeCMDKREVTQFQFTAWPDQGVPENTAPLiifhHKYRyHLSSEETGPILVHCGAGVGRTGTFIAIDS
|. | . . . | | | . | |. .. . ..|...|||.|.|. .. . |.. || ||||||||.. |.|
hrvyteycteieiggkskdkithrvlkvvvka...tgqesklnhyqwaswpdhgmpdscdta....lrll.savkkdkkpviahcsagvgrtgtlalies
LMDQMMMEGVVDVYGFVAQMRTQRNFMVQTHEQYAFIYD
.. . .| .| .| |.. || .
miaalrhprkqnvkdsfvllrkdrarsvrvfpqyvyalr
|
|||||||||
subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 22-117 | 2.4e-23 | 77.4 | In-house | 48-157 (350) | alignment | ||
Range on Protein: 22-117
Range on HMM: 48-157/350.0
KTKNRYPNILPYDHSRVVLR-------ARKDSH-GSDYINANFVDGY------GCPQKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTEHKLRSDCE
.|||| |||||.|||| |. |.| |. ..||||||.. ||||.|.|| .|..||...| . . . |..| . . |.
faknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvelnlekcy
RYWPEDGHQE
|||.| . ..
rYWqegsydd
|
|||||||||
subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 22-114 | 8.5e-17 | 55.5 | In-house | 49-157 (349) | alignment | ||
Range on Protein: 22-114
Range on HMM: 49-157/349.0
KTKNRYPNILPYDHSRVVLRAR-------KDSH-------GSDYINANFVD--GYGCPQKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTEHKLRSD
.|||| .||||.||||.|. | |. ||||||.. . .|||| | || |..||...| .| .. | | . .
faknrykdilPyehsrvklkkslksskvikastsesdsgklddyinanylkltrisvekkyiatqaPlPstvddfykvillngvklvlsLnddkelslek
CERYWPEDG
|..|| |
cdiywqels
|
|||||||||
subfamily_Cele-PTP-1_pd | Subfamily Cele-PTP-1 | 23-252 | 8.7e-21 | 69.3 | In-house | 21-253 (290) | alignment | ||
Range on Protein: 23-252
Range on HMM: 21-253/290.0
TKNRYPNILpYDHSRVVLRARKDSHGSDYINANFVDgYGCPQKYIAAQGPLTET-------IKDFWRLIWEKGCTTIVMLGDTEHKLRS----DCERYWP
..|... | ..||||. . .||| ||.| . .. |. | |.... |..|| .. . . .|||.. | | . |..| |
mdqRlevpL.veatrvvLkgygkrfnddyiHAnrvt.cpnglrliltqsPqekitekrnStiekfwwmakqEkvkqvVmlcefeeksantslfaCakYvp
ED--GHQEYGDVAVSVVDVTHMTDWTVRTFLVWVRLHPECmdkrEVTQFQFTAWPDQGVPENTAPLIIFHHKyryhLSsEETGPILVHCGAGVGRTGTFI
| .. .... |. . . | .|. .| . | || .. | . |.|.| |. .| . .. |..||| |. | ..
esvgeelkfkgltvkCkskekeddvetRelvvkfddeeef....tvtHsllkgWnklnvqedtktllsliqk....vk.asktpvivHcvdGiSrsAala
AIDsLMDQMMM--EGVVDVYGFVAQMRTQRNFMVQTHEQYAFIYD
||. | |... .| | . . ..| ||. ........||.
aii.lgyQkiaetsgsvkledvlkalrkqralaitsalelafvda
|
|||||||||
subfamily_eak_pd | Subfamily eak | 24-170 | 1.4e-11 | 38.4 | In-house | 55-196 (332) | alignment | ||
Range on Protein: 24-170
Range on HMM: 55-196/332.0
KNrYPNILPYDHSRVVLRARKDShGSDYINANFVDGYGCPQKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGD-TEHKLRsDCERYWPEDG--HQEYGD
.| .|.|||. | | . . |||| .. .||| . . . . ||... |. .||.| . | || ..|.|... ..|
rn.vvkivpydrylvrltssqln.rlGyinaslaefsevGrkyiltGiasedkvfafwqmvleqkspaivqlledvelkle.ksdkyfpdktreelkfGi
VAVSVVDVTHMTDWTVRTFLVWVrlhpeCMDKREVTQFQFTAWPDQGVPE
. | . . .| . . . . .| ... | . .|
ldverkefvkrniletrllelsk.....GnethrvlhykvfGwtettlpk
|
|||||||||
subfamily_Sponge-PTP-4_pd | Subfamily Sponge-PTP-4 | 31-169 | 1e-11 | 39.3 | In-house | 3-127 (130) | alignment | ||
Range on Protein: 31-169
Range on HMM: 3-127/130.0
LPYDHSRVVlrarkdshGSDYINANFVDGYGCPQKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTEHKlrsdcERYWPEDGHQEYG--DVAVSVVDV
|... ||. | .||||.|| | ..|. .| ||..| |||... |. .|.|| | . . |||. |. |. |.. |
lefevsrlq........gntyinasfvGllgrtaeylltqhpladtsmdfwkmmleryvnvlvvlgsveee.....deywpdsePlewyeediivtltdr
THMTDWTVrtflVWVRLHPECMD-KREVTQFQFTAWPDQGVP
. .. . . .. .. .| || . || .|
defknika....snleiesdlneshqaltmfqisnwpsdgtt
|
|||||||||
0044763 | (Phosphotyrosine protein) phosphatases II | 32-253 | 1.3e-36 | 121.3 | In-house | 1-166 (178) | alignment | ||
Range on Protein: 32-253
Range on HMM: 1-166/178.0
PYDHSRVVLRARKDSHGSDYINANFVDGYgcpqKYIAAQGPltetiKDFWRLIWEKGCTTIVMLGDTEHKLRSDCERYWPEDGHqeygdvavsvvdvthm
|.|..||.| . . .||||||...... |.....| |...|..| |.|.||.| .. . . .| .||||. .
pldrtrvllsnleglersdyinaseilpg....lylgslpp.....addlellkelgithivnlteelelgflkcdpywpeeag................
tdwtvrtflvwvrlhpecmdkrevTQFQFTAWPDQGVPENTAPLIIFHHKYRYHLSsEETGPILVHCGAGVGRTGTFIAIDSLMDQmmmeGVvDVYGFVA
|.... .|| |||. .. . |.. . .|. |. ||.|||| |||||.||..|.. .. . |. ... ..
........................iqylhipipDhgvpdllehflefvefieeald.ekggpvlVHCsaGvgRsgtlvaaylmkkl....gl.sleeaie
QMRTQRNfMVQTHEQYAFIYDV
..| .|. .|.. .|. ..|..
lvrerRp.ivpnpgqlrqLyef
|
|||||||||
0046846 | (Phosphotyrosine protein) phosphatases II | 42-253 | 6.1e-41 | 135.4 | In-house | 5-168 (176) | alignment | ||
Range on Protein: 42-253
Range on HMM: 5-168/176.0
ARKDSHGSDYINANFVDGYgcpqKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTEHKLRSDCERYWPEDGHQEYgdvavsvvdvthmtdwtvrtflv
. . ..||||||...|. ..|| |||| .|. ||.....| |.|..|.| . .. | .| .|||| ..
llgldldldyinanlilgs....rpiatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpeleklgi.......................
wvrlhpecmdkrevtQFQFTAWPDQGVPENtAPLIIFHHKYRYHLSSEetGPILVHCGAGVGRTGTFIAIDslmdQMMMEGVVDVYGFVAQMRTQRN-FM
|.... ||| |||. . |. . | .|.. ||.|||| ||.|||||..|.. .. | ..|. .|..| || ..
...............qylhlpwpDhgvpdl.elllellefirealkeg..gpvlVHCsaGigRtgtlvaay....llelekglsveealalvreqRplga
VQTHEQYAFIYDV
||| ||| |.|..
vqtpeQyrflyef
|
|||||||||
0043147 | (Phosphotyrosine protein) phosphatases II | 47-251 | 1e-44 | 147.6 | In-house | 3-154 (172) | alignment | ||
Range on Protein: 47-251
Range on HMM: 3-154/172.0
HGSDYINANFVDGYGCPQKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTehklrsdcerywpedghqeygdvavsvvdvthmtdwtvrtflvwvrLH
.|||||||...|.| .|...|| |||| .|. ||||...|.|.|.||.| . |.
egsdyinasyldlyyipdrfiatqgplrntladfwrmlkelgithivnltel..............................................ly
PECMDKREVTQFQFTAWPDQGVPeNTAPLIIFHHKYRYHLSSEETGPILVHCGAGVGRTGTFIAIDSLMdqM-MmegvvDVYGFVAQMRTQRNFMVQTHE
. .|.. |.... |||.||| ... |. | . . .| .. ||.|||| ||||||||..|.. .. . . ... ||..|..|. .||. .
dpellerlgiqylylpwpDhgvp.llellleflefidellalspggpvlVHCsaGvgRtgtlvaaylml..lgl.....sleeavalvrekRpgavqnps
QYAFIY
|| |.|
qyrfly
|
|||||||||
0051429 | (Phosphotyrosine protein) phosphatases II | 48-259 | 4.1e-54 | 179.3 | In-house | 3-225 (272) | alignment | ||
Range on Protein: 48-259
Range on HMM: 3-225/272.0
GSDYINANFVDGYGC---PQKYIAAQGPLTETIKDFWRLiWEKGCTTIVMLGDTEHKLRSDCERYWP------------EDGHQEYGDVAVSVVDVTHMT
|.||||..|.||| | ......|||. |..||||| .| |..|||.| ..| . | .|.|||| .. .||.. | .. .....
lsgyiNardvggygrvvkpgrlyrsggplpltaadfwrl.kelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseelll
DWTVRTFLVWVRLHPECMdkREVTQFQFTAWPDQGVPENTapliiFHHKYRYHLSseeTGPILVHCGAGVGRTGTFIAIDSLMDQMMMEGVVD-------
|...|..|.. |... . |||.....|.||| |||... ... .. |. ||.|||| ||..||||..|.. |. .. .| .||
dyilrellltlllsagea..revmhlhytdwpdhgvpqea.....llellellld...ggpvlvHCsaGkdRTGtvvallllllgvsletivddYlltnl
-VYGFVAQMRTQRNFMVQTHEQYAFIYDVLRDAsL
....|...| || .||| |||.|.|..|... |
yleeaveelraqrpgavqteeqylflyeallel.l
|
|||||||||
0036282 | (Phosphotyrosine protein) phosphatases II | 48-252 | 6.1e-48 | 158.1 | In-house | 1-164 (174) | alignment | ||
Range on Protein: 48-252
Range on HMM: 1-164/174.0
GSDYINANFVDGYGCPQKYIAAQGPLTetikdFWRLIWEKGCTTIVMLGDTEHKLRSDCERYWPEdghqeygdvavsvvdvthmtdwtvrtflvwvrlhP
|||||||...|.. .. ..|| ||||. ||....| |.||.||| . ... . | .||||
gsdyinaspldlsyitprliagqgpla.....fwemlkelgittvvmlleekelglykcinywpe..................................l
ECMDKREVTQFQFTAWPDQGVPENTApLIIFHHKYRYHLSSEETGPILVHCGAGVGRTGTFIAIDSLMDQMMmEGVVDVYGFVAQMRTQRNFMVQTHEQY
.|.. |.... ||| |||. . |. | . .||. . ||.|||| ||||||||..|.. .. ... |..||.. .|...|.|| |||| .||
redlerlgiqylylpwpDhgvpdlsi.llefvkfveealsedpggpvlVHCsaGvgRtGtlvaaylmlrgll.eslvdaldlvrelRlqrpgmvqtpsQy
AFIYD
|.|.
rflyy
|
|||||||||
0051082 | (Phosphotyrosine protein) phosphatases II | 48-253 | 1.3e-35 | 117.5 | In-house | 2-148 (151) | alignment | ||
Range on Protein: 48-253
Range on HMM: 2-148/151.0
GSDYINANFVDGYgcpqkYIAAQGPLTetikDFWRLIWEKGCTTIVMLGDTEHKLrsDCERYWPEDGhqeygdvavsvvdvthmtdwtvrtflvwvrlhp
|||||...|.|. ... .||| ||..|..| |..|||.| ..|. | .|.|| |
lsdyinfsyvtgg.....lyrsggpla....dflellkelgiktivnlrseeerg..ycpeylpelg.................................
ecmdkREVTQFQFTAWPDQGVPENTAPLIIFHHKYRYhlssEETGPILVHCGAGVGRTGTFIAIDSLMdQMmmegvVDVYGFVAQMRTQRNFMVQTHEQY
.||...... |||.|.|.... .. |..... . ||.|||| ||.|||||..|.. .. .. |... ....| .| .||...|.
.....ievlhipildwpdpglplsfdavleflellld....kkngpvlvHCsaGkgRTGtlvalylml.lg.....vsleealeeyrlkrpgvvqpnqqf
AFIYDV
|.. .
lfqlfa
|
|||||||||
0049260 | (Phosphotyrosine protein) phosphatases II | 56-252 | 1.5e-40 | 133.7 | In-house | 1-144 (152) | alignment | ||
Range on Protein: 56-252
Range on HMM: 1-144/152.0
FVDGYGCPQKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTEHKLRSDCERYWpedghqeygdvavsvvdvthmtdwtvrtflvwvrlhpecmdkrev
|.|||. |...||.|||. .|..||||...| |.|||||| . . . . ||.|.
fidgyampfefiatqgpgpntladfwrmlkelgittivmltellelgklkceqyi.............................................
tQFQFTAWPDQGVPENTAPLIIFHHKYRYHlSSEETGPILVHCGAGVGRTGTFIAIDSLMdqmmmeGVVDVYGFVAQMRTQRNFMVQTHEQYAFIYD
|.... ||| |||... |..... . . .. ||.|||| ||||||||..|.. .. |... .||..|..|. .|....|. |.|.
.qylhlpwpDhgvpdlsqlllflllfiekl.aldkggpvlVHCsaGvgRtgtlvaaylml......lgvsleeavalvrekRpgavpnpgqlrflye
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 58-138 | 8.2e-09 | 29.3 | In-house | 230-308 (440) | alignment | ||
Range on Protein: 58-138
Range on HMM: 230-308/440.0
DGYGCPQKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTEHKlrsDCERYWPEDGH-QEYGDVAVSVVDVTHMTDWTVRT
.|| . .||.| || |. |||||. . .||.|| . . | | ||| . .| .| | |||
egyskknafiatqmpldstvldfwrlvhdyristiimlnqlndk...tcsiywpvntrsvtfgpftvghkgsenmnrvkvrt
|
|||||||||
subfamily_Anemone-PTP-3_pd | Subfamily Anemone-PTP-3 | 64-253 | 4.4e-29 | 96.1 | In-house | 5-199 (199) | alignment | ||
Range on Protein: 64-253
Range on HMM: 5-199/199.0
QKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTEHKLRSDCERYWP--EDGHQEYGDVAVSVVDVTHMTDWTVRTFlVWVRLHPECMDKREVTQFQFT
..|||.| || ||. |||...|| | |||. | ... .| ||| | | .|| ..|.. .| |.|. .. . . ||....|||
rryiatqhplretmadfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytital.iltnnttappstreishyqft
AWPDQGVPeNTAPLIIF---HHKYRYHLSSEETGPILVHCGAGVGRTGTFIAIDSLMD--QMMMEGVVDVYGFVAQMRTQRNFMVQTHEQYAFIYDV
.| .. | | | .. | . . | |..||| | | || |.|.| . . |||.. ..| | .. . ..| |||.|
swkekttp.nvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiisslqhynfiyqv
|
|||||||||
subfamily_Nvec-PTP-3_pd | Subfamily Nvec-PTP-3 | 64-253 | 4.4e-29 | 96.1 | In-house | 4-198 (198) | alignment | ||
Range on Protein: 64-253
Range on HMM: 4-198/198.0
QKYIAAQGPLTETIKDFWRLIWEKGCTTIVMLGDTEHKLRSDCERYWP--EDGHQEYGDVAVSVVDVTHMTDWTVRTFlVWVRLHPECMDKREVTQFQFT
..|||.| || ||. |||...|| | |||. | ... .| ||| | | .|| ..|.. .| |.|. .. . . ||....|||
rryiatqhplretladfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytital.iltnnttappstreishyqft
AWPDQGVPeNTAPLIIF---HHKYRYHLSSEETGPILVHCGAGVGRTGTFIAIDSLMD--QMMMEGVVDVYGFVAQMRTQRNFMVQTHEQYAFIYDV
.| .. | | | .. | . . | |..||| | | || |.|.| . . |||.. ..| | .. . ..| |||.|
swkekttp.nvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiisslqhynfiyqv
|
|||||||||
subfamily_Cele-PTP-5_pd | Subfamily Cele-PTP-5 | 64-256 | 3.4e-06 | 19.9 | In-house | 115-307 (346) | alignment | ||
Range on Protein: 64-256
Range on HMM: 115-307/346.0
QKYIAAQGPLTE---TIKDFWRLIWEKGCTtIVMLGDTEHKLRSDCER-YWPEDGH-QEYGDVAVSVVDVTHMTDWTVRTflvwVRLHPECMDKREVTQF
.| | || | | ..||| .|... .| | . ||. . |.| | | . . | | . . || . |
hklivaqlpqmenesfvedfwymiyqeqih.lvylmvpddklkntttslfndenggyqytgkmfinnrradvsgdpkeyt....ievlpegnsdsvicqv
QF-TAWPDQGVPENTAPLIIFHHKYRYHLSSEETGPILVhCGAGVGRTGTFIAIDSLMDQMMMEGVVDVYGFVAQMRTQRNFMVQTHEQYAFIYDVLRD
. . | | .| |.| . |.. ...| .| | ||. .|| ..|. ... . ... || |.. ||| || .. |
hhhapwkhlqqppktlpiikmihqflsekqvqnagvcvv.slfgcgracsfigalyainqlnngiepniceimknikqqrpggvesfaqyasiyaivfd
|
|||||||||
subfamily_Cele-PTP-7_pd | Subfamily Cele-PTP-7 | 71-250 | 1.3e-16 | 55.0 | In-house | 98-280 (302) | alignment | ||
Range on Protein: 71-250
Range on HMM: 98-280/302.0
GPLTETIKDFWRLIWEKGCTTIVMLGDTEHKLRSDCERYWPED--GHQEYGDVAVSVVDVT-HMTDWTVR-TFLVW-VRLHPEC---MDKREVTQFQFTA
| .|.. .| || . . .| | . . | |. .. |. ..| .| |.| .. ..| . .| .. | .. | |. | ..|.|
vpkkstlekhwalieqynvaivvqlcsfvedeekkcaeyysdkvggelkfgrytvktvsvktdleeftdkksfklytveiknekkkkkvkktvdilafsa
WPDQGVPENTAPLI-IFHHKYRYHLSseetgpILVHCGAGVGRTGTFIAIDSLMDQMMMEGVVDVYGFVAQMRTQRNFMVQTHEQYAFI
||| | |... . . |... | . .|||| ||||||||..|| .. . . | |. | .|. | ||...| ..
wpdhGapkeaytaldilkfcesykkn......vlvhcsaGvGrtGtlvaikyGiqlcskkkvtdllsivlpvrqcryGavqdeqqliyl
|
|||||||||
subfamily_hpo-7_pd | Subfamily hpo-7 | 73-251 | 3.6e-18 | 60.4 | In-house | 43-220 (263) | alignment | ||
Range on Protein: 73-251
Range on HMM: 43-220/263.0
LTETIKDFWRLIWEKGCTTIVMLGDTEHKLRSDCERYWP--EDGHQEYGDVAVSVVDVTHmtDWTVRTFLVWVRLHPeCMDKREVTQFQFTAWPDQGVPE
| .||. |.. | .. ...|||.| . . . .|..|.| |. | . .|.|.. .| . | ..| . | ..|...... |... ||
lvqtidkfyqtivqtktevvvmLcDfneegvekcssyfPlekdekqklanvnvcttkvqs..dvllktlellstlge.KkkthtvkhysykgWiekndpe
NTAP-LIIFHhkyryhLSSEEtGPILVHCGAGVGRTGTFIAIDSLMDQMMME------GVVDVYGFVAQMRTQRNFMVQTHEQYAFIY
.. | |.. . . .. ||| .|.||. | .... .|.. . .| .. ..| .|. ..| | ||
lareilnilk......varns.kslvvhcstGiGrsaafsvaElvyqkmirsldttstveldylsLleelrssrkraihtPmqLafsi
|
|||||||||
subfamily_Cele-PTP-9_pd | Subfamily Cele-PTP-9 | 75-251 | 1.5e-19 | 65.1 | In-house | 39-214 (255) | alignment | ||
Range on Protein: 75-251
Range on HMM: 39-214/255.0
ETIKDFWRLIWEKGCTTIVMLGDTEHKLRSDCERYWP--EDGHQEYGDVAVSVVDvtHMTDWTVRTFLVWVRLHPeCMDKREVTQFQFTAWPDQGVPENT
|.. |.. | .. ...|||.| . . . .|..|.| |... . ||.|.. . ..| .|| . | ..|. .... |... ||..
ltvdkfyqtivqtktevvvmlcdfaeegvekcssyfplekdeklkladvnvtttk..ssadvvlrtleitstlge.kkkthtvkhysykGWieknaPela
APLIifhhkYRYHLSSEEtGPILVHCGAGVGRTGTFIAIDSLMDQMMME------GVVDVYGFVAQMRTQRNFMVQTHEQYAFIY
. . ... . ...||| .|.||. .|. .... .|.. . .| .. ..| .|. ..| | ||
reil.....nilkvvrds.ksvvvhCstGiGrsaafvlaelvyqkmirsldttetveldylslleelrskrkraihtPlqlafsi
|
|||||||||
0048076 | (Phosphotyrosine protein) phosphatases II | 119-254 | 2e-25 | 84.5 | In-house | 14-139 (145) | alignment | ||
Range on Protein: 119-254
Range on HMM: 14-139/145.0
GDVAvSVVDVTHMTDWTVRTFLVWVRLHPECMdkREVTQFQFTAWPDQGVPENTAPLIIFHHKYRYHLSSEetGPILVHCGAGVGRTGTFIAIDslmdQM
|.. ...|. .. |. ..| | . . . |...|.... ||| |||. .. |. | . . .|... ||.|||| ||||||||..|.. |
gslp.taldlellkdlgittvlnltselelle..rlgiqylylpwpDhgvpdllellleflefieealkeg..gpvlVHCsaGvgRtgtlvaay....lm
MMEGvVDVYGFVAQMRTQRNFMVQTHEQYAFIYDVL
...| |... ....|.|| ..|.. .|. |.|...
lllg.vsleealelvrsqrpgavpnpgqlrflyefe
|
|||||||||
0048179 | (Phosphotyrosine protein) phosphatases II | 124-252 | 2.4e-24 | 81.1 | In-house | 18-139 (144) | alignment | ||
Range on Protein: 124-252
Range on HMM: 18-139/144.0
SVVDVTHMTDWTVRTFLVWVRLHPECMDKREVTQFQFTAWPDQGVPENTAPLIIFHHKYRYHLSseETGPILVHCGAGVGRTGTFIAIDslmdQMMMEGv
...|. .. .. ..| . . .. .||..|.... ||| |||. .. |. | . . .|. | ||.|||| ||||||||..|.. |...|
taldlellkklgittvinlteeyepefleregiqylhlpwpDhgvpdllellleflefieeale..eggpvlVHCsaGvgRtgtlvaay....lmkklg.
VDVYGFVAQMRTQRNFMVQTHEQYAFIYD
.... .|..|..| ..|.. .|. |...
lsleealalvrsrrpgavpnpgqlrfLle
|
|||||||||
subfamily_CDC14_pd | Subfamily CDC14 | 143-244 | 1.4e-06 | 22.3 | In-house | 217-311 (328) | alignment | ||
Range on Protein: 143-244
Range on HMM: 217-311/328.0
VRLHPECMDKREVTQFQFTaWPDQGVPENTAPLIIFHHKYrYHLSSEETGPILVHCGAGVGRTGTFIAIdSLMDQMMMEgvvdVYGFVAQMRTQRNFMVQ
||| . |... |. | |. . . | .|. ... . .| | ||| ||.|||||.|| || . . .| .| | .|
vrLnkklYdakkftdaGfd.hkDlffiDGstPsdaivkkf.leiaekaeGaiavhCkaGLGrtGtLiac.ylmkhyrft....aaeaiawlricrPGsvi
TH
..
gp
|
|||||||||
subfamily_PTPDC1_pd | Subfamily PTPDC1 | 147-251 | 1.7e-07 | 25.9 | In-house | 75-169 (182) | alignment | ||
Range on Protein: 147-251
Range on HMM: 75-169/182.0
PECMDKREVTQFQFtAWPDQGVPENTAPLIIFHHkyryHLSSEETGPILVHCGAGVGRTGTFIAIdslmdQMMMEGVVDVYGFVAQMRTQRNFMVQTHEQ
.| . ..... ..| .|.| ||. . | | .. . | . ||| || |||| || .. .. . .| .| .||.||
lealmeqgiyvynf.gwkDygvasleriLdivkv....vafalqegkvavhChaGlGrtGvliac.....ylvyakrltaekaiklvrskrpksiqtreq
YAFIY
..
velvk
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 150-283 | 1.8e-25 | 84.1 | In-house | 86-219 (440) | alignment | ||
Range on Protein: 150-283
Range on HMM: 86-219/440.0
MDKREVTQFQFTAWPDQGVPENTAPLIIFHHKYRYHLSSEETGPILVHCGAGVGRTGTFIAIDSLMDQMMMEGVVDVYGFVAQMRTQRNFMVQTHEQYAF
.. | . |... .|||.|||. ..|.. . . ||.|||| ||.|||| ||.||.. . .|.. |. || .| |||| |||||
iesrtlkqyhyqgwpdkgvpkfagpvlkmiqdvnesqekagngpllvhcsagagrtgviiavdsilreakrsdqidifsfinsmrnnrpqmvqtpeqyaf
IYDVLRDASLCGITEIPSQEIASSLLVLRDNDPD
..... .. ||| | | ..|. . .. .|
vheavlegllcgdtliledditerveqiqwpnph
|
|||||||||
0038934 | (Phosphotyrosine protein) phosphatases II | 150-250 | 6e-10 | 34.6 | In-house | 70-176 (194) | alignment | ||
Range on Protein: 150-250
Range on HMM: 70-176/194.0
MDKREVTQ----FQFTAWPDQGVPENTAPLIIFHHKYRYHLSSEETGPILVHCGAGVGRTGTFIAIdSLMDQMMMeGVVDVYGFVAQMRT----QRNFMV
|..|... . .||.|.. ... | | . .|. . | ..||| ||.|||||..| |. . | . . .......| .....
YdpeefekagieylklpfpddgtvPsleillrfldlvdeflnedpggvvaVHCkaGlgRtGtlvaa.YLiyrlgm.saeeAialfrekRpgaipnqdyle
QTHEQYAFI
. .. | ..
allkrykel
|
|||||||||
subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 151-255 | 5e-18 | 59.9 | In-house | 213-341 (350) | alignment | ||
Range on Protein: 151-255
Range on HMM: 213-341/350.0
DKREVTQFQFTAWPDQGV---PENTA------PLIIFHHKYRYHLSSEETGPILVHCGAGVGRTGTFIAIDSLMD-----QMMMEGV---------VD-V
| .| |.|. |.| .. ||. . .| . || .... |||||| ||||||||....|||. ... . | .
dPyvvyqlqvknWkDlslllnPesilqalevkndliddlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaaktrDli
YGFVAQMRTQRNFMVQTHEQYAFIYDVLR
| ..| || |||. .|. |||. |.
siivnelrkqrismvqnldqfifiYeall
|
|||||||||
subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 154-254 | 4.6e-12 | 39.9 | In-house | 219-340 (349) | alignment | ||
Range on Protein: 154-254
Range on HMM: 219-340/349.0
EVTQFQFTAWPDQGVPENT---------APLIIFHHKYRYHLSSEETGPILVHCGAGVGRTGTFIAIDSLMD--QMMMEGVV---------D-VYGFVAQ
|. |.|. |.| .. | . .| | .| .... ..|||| || ||||... .|.|.. ... . . | .. | .
ellqlqvknwldlslllnPisilqalevkndliddlfarlyldtdqlstllvhcsaGcGrtGvlvtldlllsileplqnesnkiklqallkDlisiivne
MRTQRNFMVQTHEQYAFIYDVL
.| || ||| |. .||. |
lrkqrismvqnlaqfiaiyeal
|
|||||||||
PTPc_DSPc_SM00012 | 155-254 | 1.4e-34 | 113.8 | In-house | 2-103 (105) | alignment | |||
Range on Protein: 155-254
Range on HMM: 2-103/105.0
VTQFQFTAWPDQGVPENTAPLIIFHHKYRYHLSSEE-TGPILVHCGAGVGRTGTFIAIDSLMDQMMME-GVVDVYGFVAQMRTQRNFMVQTHEQYAFIYD
|.....|.|||.||||.. ... . .. . . . .| ..|..||| |||||||||.|.| |..|.. | . ||.. .| ..|.||. |||| ||| |.|.
vkhyhytgwpdhgvPeesdsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgmvqteeqylflyr
VL
.|
al
|
|||||||||
0048567 | (Phosphotyrosine protein) phosphatases II | 162-211 | 5e-06 | 21.0 | In-house | 44-97 (157) | alignment | ||
Range on Protein: 162-211
Range on HMM: 44-97/157.0
AWPDQGvPENTAPLIIFHHKYRYHLS--SEETGPILVHCGAGV---GRTGTFIAI
. | | | | | |. | .| |. ... ..| ||| || |||.|.|.
fffdfG.PlnlailyrFilklnkflkilelagkaiavhckaglkkrgrtatLigc
|
|||||||||
PTEN_1 | 166-247 | 4.9e-07 | 24.7 | In-house | 100-184 (196) | alignment | |||
Range on Protein: 166-247
Range on HMM: 100-184/196.0
QGVPENTAPLIIFHHKYRYHLSSE-----ETGPILVHCGAGVGRTGTFIAIdSLMDQMMmEGVVDVYGFVAQMRTQRNFMVQTHEQY
... .|| . .... . . . . . .|||| ||.||.|| .| || . . . .|...|..... .|..
fpieDhgapslselfdicksfiewllsdpngnvVlVHCkaGlgRsGtvvaa.yLmykgk.ltadeAlelvrekRppgapnspsqerl
|
|||||||||
subfamily_PTEN_pd | Subfamily PTEN | 179-250 | 3.1e-07 | 25.5 | In-house | 102-172 (184) | alignment | ||
Range on Protein: 179-250
Range on HMM: 102-172/184.0
HHKYRYHLSSEETGPILVHCGAGVGRTGTFIAIdSLMDQMMMEGVVDVYGFVAQMRTQRNFMVQTHEQYAFI
.. . .|..... . ||| || ||||. |. |. ....| .. . |..||. . |. | ..
vediekwleedkknvvvvHCkaGkGRtGvliva.yllkslllekaeealelfaeaRtknkkgvtiPsqrRYv
|
|||||||||
subfamily_eak_pd | Subfamily eak | 183-254 | 6.6e-07 | 23.0 | In-house | 229-301 (332) | alignment | ||
Range on Protein: 183-254
Range on HMM: 229-301/332.0
RYHLSSEETGPIlVHCGAGVGRTGTFIAIDSLMDqMMME---GVVDVYGFVAQMRTQRNFMVQTHEQYAFIYDVL
.|. . || . . | |.|.|. || |. .. . . | .. .....|. | . |..|||...
kyihtppsfapi.iqsarGsaraGvfvvidllir.lidnkkknlysvedlilkvkskrihsvlvalqhsfiyeiv
|
|||||||||
PTPc_motif_SM00404 | 187-236 | 3.6e-07 | 25.2 | In-house | 76-123 (140) | alignment | |||
Range on Protein: 187-236
Range on HMM: 76-123/140.0
SSEETGPILVHCGAGVGRTGTFIAIdSLMDQMMMEgVVDVYGFVAQMRTQ
. .. | .|||| ||| |..|.|. ||... .. . ..| || . | .
aekkggkvlVHCqaGvSRSatliia.Ylmryrqls.laeayefvkerRpi
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 188-255 | 6.3e-16 | 52.9 | In-house | 244-312 (319) | alignment | ||
Range on Protein: 188-255
Range on HMM: 244-312/319.0
SEETGPILVHCGAGVGRTGTFIAIDSLMDQMMME-GVVDVYGFVAQMRTQRNFMVQTHEQYAFIYDVLR
|. ||. ||| ||||||. || | . .. ||. | ..| .| |.| |||.||| ||
resqGPlvvhcsdGvGrtGlviasdiairsleeskrsvdiPqlvssvrrdrasavltkeqyefiykvls
|
|||||||||
DSPc | Dual specificity phosphatase, catalytic domain | 189-236 | 1.5e-06 | 23.1 | Pfam-A | 71-116 (133) | alignment | ||
Range on Protein: 189-236
Range on HMM: 71-116/133.0
EETGPILVHCGAGVGRTGTFIaIDSLMDQMMMeGVVDVYGFVAQMRTQ
.. . .|||| ||. |..|.| | ||... . . . | || . | .
qkgkkvlVHCqaGisRSatli.iaYlmktknl.slneAyefvkerrsk
|
|||||||||
DSPc | Dual specificity phosphatase, catalytic domain | 189-236 | 1.5e-06 | 23.1 | In-house | 71-116 (133) | alignment | ||
Range on Protein: 189-236
Range on HMM: 71-116/133.0
EETGPILVHCGAGVGRTGTFIaIDSLMDQMMMeGVVDVYGFVAQMRTQ
.. . .|||| ||. |..|.| | ||... . . . | || . | .
qkgkkvlVHCqaGisRSatli.iaYlmktknl.slneAyefvkerrsk
|
|||||||||
subfamily_DSP10_pd | Subfamily DSP10 | 191-235 | 8.9e-06 | 19.7 | In-house | 92-134 (159) | alignment | ||
Range on Protein: 191-235
Range on HMM: 92-134/159.0
TGPILVHCGAGVGRTGTfIAIDSLMDQMMMEgVVDVYGFVAQMRT
.|||| ||. | | ..| || .. . . | | || . |.
gsrvLvhCqaGisrsat.vviaYlmkhlnls.lndaykfvkekrp
|
|||||||||
subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 192-253 | 2.5e-13 | 44.5 | In-house | 229-290 (297) | alignment | ||
Range on Protein: 192-253
Range on HMM: 229-290/297.0
GPILVHCGAGVGRTGTFIAIDSLMDQMMMEGVVDVYGFVAQMRTQRNFMVQTHEQYAFIYDV
..|||| |||||.| . | ..... . . || .. ..| || .||| ||. ..||.
ayllvhcsaGvGrsGvvvlsdvilaklrkkripdvaailsilreqrarlvqtleqfellyda
|
|||||||||
subfamily_Sponge-PTP-7_pd | Subfamily Sponge-PTP-7 | 195-257 | 3.3e-15 | 50.2 | In-house | 2-64 (69) | alignment | ||
Range on Protein: 195-257
Range on HMM: 2-64/69.0
LVHCGAGVGRTGTFIAIDSLMDQMMMEGVVDVYGFVAQMRTQRNFMVQTHEQYAFIYDVLRDA
.||| .| ||||||||| | .. | .||.. | || | || .| ||.| | .|
vvhcssgtgrtgtfiaimvemarikseklvdifnnvqymrkcrpmmvmneieyifihdalvea
|
|||||||||
subfamily_Sponge-PTP7_pd | Subfamily Sponge-PTP7 | 196-257 | 2.3e-15 | 50.7 | In-house | 2-63 (69) | alignment | ||
Range on Protein: 196-257
Range on HMM: 2-63/69.0
VHCGAGVGRTGTFIAIDSLMDQMMMEGVVDVYGFVAQMRTQRNFMVQTHEQYAFIYDVLRDA
||| .| ||||||||| | .. | .||.. | || | || ..| ||.| | .|
vhcssGtGrtGtfiaimvemarikseklvdifnnvqymrkcrpmmvmneneymfihdalvea
|
|||||||||
0051299 | (Phosphotyrosine protein) phosphatases II | 264-543 | 1.3e-77 | 256.4 | In-house | 4-286 (288) | alignment | ||
Range on Protein: 264-543
Range on HMM: 4-286/288.0
EIPSQEIASSLLVLRdndPDIIRQRQDEFEVSLACVASvsvfsRNRERTRNMAAPKRSDNFSFVAVDTNRIRLSITNDIPCSEYINASYIDSYNEAHEYI
||. .|... .| |. .. . . ..||| |.. .. ... .. . .. . .... | .|..|| ..... | |||||||| || ...|
eisveellklvlkll...angltglleefeellsllpd.....ltlsaallpenleknRysdilpydhsRVkLsvldgvegsdYinAsyidgynlkrkfI
ATQAPMENTINEFWQMVWEQKCTAIVMLTELQDRGQIESELYWPRDGCVRYGKYIVTKIDEEELDDHTQRSMDSL------------LVYHFQYHNWSAH
|||.|..||...||.|||||... |||||.|...|.. .. ||| .|.. ||.. || ..||.||| |.| . |.||.|.|| |
atqgPlpntvedFWrmvweqnvrvIvmltklvelgrekcaqYwplggsltygditvtllseevlddytvrtlevtnldlldgdgesrtvthfhytnwpdh
GMPPRMNGLVFLHEQVQKIQStEDHGPTVVHCSDGAGRTGVFLALAISIERLEAEDTVDIFQTVRWLRSQRPALVGSIEQYSCCYQAVKSYL
|.|. .. |. . ..|.| .. ..||.|||||.| ||||.|.|| . .|.||.| .||....|..||.||| .| . ||| .|.|. ||
gvpdspellldflrlvrkala.sgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlreqRpgmvqtpeqyrfvyealleyl
|
|||||||||
subfamily_Ptp69D_pd | Subfamily Ptp69D | 268-545 | 3.7e-65 | 215.1 | In-house | 7-288 (307) | alignment | ||
Range on Protein: 268-545
Range on HMM: 7-288/307.0
QEIASSLlVLRDNDPDIIRQRqdEFEVSLACvaSVSVFSRNRERTRNMAApKRSDNfsFVAVDTNRIRLSITNDIPCSEYINASYIDSYNEAHEYIATQA
......| . |..|.| .. |.| | .. ... |. | |... .| | .|..|. .| |.|||||.| .|.| ...|| |.
ddleeal.ksrkrdtdfglak..eyekLear..eidkstkvsekkenalk.nRyed..ikafDktRvkLkkingkedsdYinasfikgykekkkfiaaqd
PMENTINEFWQMVWEQKCTAIVMLTELQDRGQIESELYWPRDGCVRYGKYIVTKIDEEELDDHTQRSM-------------DSLLVYHFQYHNWSAHGMP
|.|.||..||.|..||. | ||||..|.. . . . ||| . |.||. .|. ..||. .|...|.. || | ..| .| .|
PveatigDfWRmiaeqevtlivmlsnlteknrkkcakYWpiedevqygdilvklvseekhsdyiiReldvskkkeesgevedsrkvvqyhytgWkDskvP
PRMNGLVFLHEQVQKIQSTEdHGPTVVHCSDGAGRTGVFLALAISIERLEAEDTVDIFQTVRWLRSQRPALVGSIEQYSCCYQAVKSYLSW
.||. | |||....... ..| ||||| |.||.|.|.||.. ...|.|||.||||.||. |||||. || |.|||. .|.|. | |.
evargllklieqvrelykln.rsPivvhCsaGvgrsgifvaldsllqqlkaedkvdifetvkdLrsqRnllvqsleqYvflyralldyssy
|
|||||||||
subfamily_ptpA1_pd | Subfamily ptpA1 | 270-409 | 4.8e-20 | 66.7 | In-house | 6-138 (418) | alignment | ||
Range on Protein: 270-409
Range on HMM: 6-138/418.0
IASSLLVLRdNDPDIIRQRQDEFEVSLACVASVSVfSrNRERTRNMAaPKRSDNfsFVAVDTNRIRLSITNDIPCSEYINASYIDSYNeAHEYIATQAPM
| ||. |. | |.. ..|| . | | . .. .| . .| | . |. |..| .| |.|||| ||| ...|.|| |.
ikssiynlk.nhikcihkikeefrlleesvgpset.s.egdkkhnts.knrytn..ilpvnhtrvqlkkiqdkegsdyinanyidgay.pkqfictqgpl
ENTINEFWQMVWEQKCTAIVMLTELQDRGQIESELYWPRD
||| .||.||||..| ||||. . .|. . ||| .
pntiadfwrmvwenrcriivmlsresencrikcdrywpeq
|
|||||||||
0045450 | (Phosphotyrosine protein) phosphatases II | 284-543 | 1.6e-67 | 223.8 | In-house | 25-304 (307) | alignment | ||
Range on Protein: 284-543
Range on HMM: 25-304/307.0
IIRQRQDEFEVSLACVASVsvfSRNRERTRNMAAPKRSDNFSFVAVDTNRIRLSITNDI-PCSEYINASYI--------DSYNEAHEYIATQAPMENTIN
.. . ||| | . . . ... .. . .. .... | .|..|| ... . | ||||||. |.|. ...||||.|...|..
fltgllkefekllsvtvfl...lgeysiallpenkdknrykdilpydhtRVklssldgsledsdYiNAsyvrvpllllldgydlkrkfIatqgPlpetve
EFWQMVWEQKCTAIVMLTELQDRGQIESELYWPRDGCV-RYGKYIVTKIDEEELDDHTQRSMDSL---------LVYHFQYHNWSAHGMPPRMNGLVFLH
.||.|.|||..|.||||||| ..|.. ||| .| . ||.. || ..||.||. | | . |.||.|..| || || .. |. .
dFwrmlweqgvtvivmltelvelgrekcaqywPdegeeltygnftvtllseehldgytvrtlevtdldgtgesrtvthfhytgwpdhgvppsfeelldfi
EQVQKIQSTE-DHGPTVVHCSDGAGRTGVFLALAISIERLEAEDT---VDIFQTVRWLRSQRPALVGSIEQYSCCYQAVKSYL
|.|.|.... ..||..||||.| ||||.|.|. . ...||.| | ||....|..||.||| | . ||| .|.|.. .|
eevrkaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrflyeallell
|
|||||||||
subfamily_PTPRA_pd | Subfamily PTPRA | 287-543 | 1e-66 | 220.1 | In-house | 33-295 (330) | alignment | ||
Range on Protein: 287-543
Range on HMM: 33-295/330.0
QRQDEFEVSLACVASVSVFSRNRERtrNMaapKRSDNFSFVAVDTNRIRLSITNDIPCSEYINASYIDSYNEAHEYIATQAPMENTINEFWQMVWEQKCT
. ..||. |. .. ..| |. ... . | .|. || . ...|.|||||.|| |.| ...||.| | |.|...||.|.|||| .
lfreefnalPagpiqatlelaskee..nk...eknrvvnilPydfsrvilsvkeGveesdyinasfidGykekdkfiaaqGPkeetvedfwrmiweqksa
AIVMLTELQDRGQIESELYWPRDGCVRYGKYIVTKIDEEELDDHTQRSM------------DSLLVYHFQYHNWSAHGMPPRMNGLVFLHEQVQKIQSTE
.|||||||..| . . ||| .|.| ||. |. ||..| | | | . .| || | .. | |.| |.. | ..|.|.. .
tivmltelkerkeekcaqywPdeGlvtyGnirvevedetvlvdytvrkflvqqlpdatrekksrlvrqfhftswPdvGvPfepiGmlkllkkvkklnqqs
DHgPTVVHCSDGAGRTGVFLALAISIERLEAEDTVDIFQTVRWLRSQRPALVGSIEQYSCCYQAVKSYL
| ||||| |.|||| |..| .||..|| ||.|..|. || ||| .| . ||| .|.... |
ag.pivvhcsaGvGrtGtfivldavlervkaerkvdvfefvkrlrlqrpqmvqtdeqyefiykvlleyy
|
|||||||||
subfamily_Sponge-PTP5_pd | Subfamily Sponge-PTP5 | 290-540 | 4.1e-54 | 178.4 | In-house | 6-264 (283) | alignment | ||
Range on Protein: 290-540
Range on HMM: 6-264/283.0
DEFEVSLACVASVSVFSRNRERTRNMAAPKRSDNFSFVAVDTNRIRLSITNDipcsEYINASYID---SYNEAHEYIATQAPMENTINEFWQMVWEQKCT
..... . .|| ... . . . .. | |..| .|..| . .||||..| ||.. ..||..|.|...|. .||.||...| |
nnnklfrevlkrlsvpdldadiasadenkrknrnqeivpadqwrvelksesr....dyinavfipvsksykqdkkyiiaqsPldrtvvdfWkmvfdekit
AIVMLTELQDRGQIESELYWPRDGCVRYGKYIVTKIDEEELDDHTQRS---------MDSLLVYHFQYHNWSAHGMPPRMNGLVFLhEQVQKIQSTEDHG
||||||.||. .|. |||..| . ||.. || .| . ... ..||. |.|. .| | . .| || . ..|. | . .|
aivmltklqedlrikCsqyWPkrGsedyGeftvtlrkettsnsfiikelllrvnssakstlllahyqvidWleygeqaiinslvkf.nkvislqteskkg
PTVVHCSDGAGRTGVFLALAISIERLEAEDTVDIFQTVRWLRSQRPALVGSIEQYSCCYQAV-K
| ||||| | |||.||.|.. |.. . .| ||.|..|. .| ||. .| . .|| ...| .
PivvhCstgiGrtavfiaasasvkdaltesvvdvfavvkimreqrmmavqtldqyklvhelvle
|
|||||||||
subfamily_PTPN6_pd | Subfamily PTPN6 | 290-549 | 7.7e-54 | 177.7 | In-house | 30-303 (306) | alignment | ||
Range on Protein: 290-549
Range on HMM: 30-303/306.0
DEFEvSLACVASVSVFSRNRERTRNMAAPKRSDNfsFVAVDTNRIRLSiTNDIPCSEYINASYID--SYNEAHEYIATQAPMENTINEFWQMVWEQKCTA
.||| .| .. ...||.. . . . | | . .| .|. |. ...| |.||||.||. . .. ..||||| .|.|...||.|||.....
eefe.elqqeeakkllsrkegakpenkeknrykn..ilPfDhtrvilk.epsvpgsdyinanyikkevkgsdksyiatqgclettvsdFWrmvwqensrv
IVMLTELQDRGQIESELYWPRDGC-VRYGKYIVTKIDEEELDDHTQRSMDS---------LLVYHFQYHNWSAHGMPPRMNGLV-FLHEQVQKIQSTE--
|||.|. .||. ||| .|||. ||...|..|.| . |.. |.......| ||.| . .. ||.. .| ...|
ivmttkevErgkekCarYWPdeeekeeyGkisvtnvseksladYilRelsvskkkkkkeerevfqyhfksWPdhgvpkdpgavLdfledvnrkqeeleea
DHGPTVVHCSDGAGRTGVFLALAISIERLEA---EDTVDIFQTVRWLRSQRPALVGSIEQYSCCYQAVKSYLSWRTRA
..||.|||||.| |||| |. . | .. .| . .|| ..|. .|.|| || .|| |.|.| |. ....
eagpivvhCsaGiGRtGtfiviDillkliekkgldadidiqklvksvreqrsglvqteqqykfvykaikkyietkkkl
|
|||||||||
subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 304-544 | 4.4e-56 | 185.0 | In-house | 32-279 (287) | alignment | ||
Range on Protein: 304-544
Range on HMM: 32-279/287.0
VFSRNRERTRNMAAPKRSDNF--SFVAVDTNRIRLSitndIPCSEYINASYIDSYNEAHEYIATQAPMENTINEFWQMVWEQKCTAIVMLTELQDRGQIE
| |. | | |.| . | .. | .|. | .||||..||.|.|....|....|| ||. .||....... ||||||..... .
vtqredevthniasqnkdknRltqilvpdnyrvllk....gehpdyinavfidgykekkafiiaesPmfntarnfWkliddrnvtaivmlcqekendeev
SELYWPRDGCVRYGKYIVTKIDEEELDDHTQRSM---------DSLLVYHFQYHNWSAHG-MPPRMNGLVFLHEqVQKIQSTEDHGPTVVHCSDGAGRTG
||| . .| .|.| .. ..|| .. ..| . | . | .|. || .| .. |. ..| | | . ... ||||||. ||..
cyqyWpeeksvvlGeyniellneevnagyierklevknknkagdkqqvkqyqitnWdstgkvtepqtillviee.myktqrkrgntsivvhCsdtvGrsa
VFLALAISIERLEAEDTVDIFQTVRWLRSQRPALVGSIEQYSCCYQAVKSYLS
.|.| |..|.. . | ..|.|| .. | |.| | .||| ...| ||.
mfcaaattinkckteGviDvfqvlksqriqkpgsvqtveqykfindivleyld
|
|||||||||
subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 307-544 | 5.4e-64 | 211.3 | In-house | 46-291 (298) | alignment | ||
Range on Protein: 307-544
Range on HMM: 46-291/298.0
RNRERTRNMAAPKRSDNFSFVAVDTNRIRLSITNDIPCSEYINASYIDSYNEAHEYIATQAPMENTINEFWQMVWEQKCTAIVMLTELQDRGQIESELYW
. | .|. . |. . .|.| |..|. ... |.|||||....|.. . .||||||...|...||.||.|.. ..|||||.|.. .... . ||
eekevarkpenkkkNRyadiialdssRvvLekedadeesdYiNAsflhaykgrnafiatqaPltetvedFWrmvteedigtiVmltnleeldktkyhkyw
PRDGCVRYGKYIVTKIDEEELDDHTQRSM--------DSLLVYHFQYHNWSAHGMPPRMNGLVFLHEQVQKIQSTEDHGPTVVHCSDGAGRTGVFLALAI
| .| .||. |. .|| | ..| . .. | .... .|. .|.| .. .. | ..|.. |. . | .|.||.| ||.| | |.
PdegketygeitvsllskeefadlivrklkvskkkeekerevrqlhftsWpdkgvpenatsvldllrkvrasqqqagnkpvivqCsaGvgRsGtfiaids
SIERLEAEDTVDIFQTVRWLRSQRPALVGSIEQYSCCYQAVKSYLS
.||...| .||.||.|. || .||..| . |||. .|.|| .|.
vlervkkeqvvDvfqvvkvlRkkrpgavqteeqYvfiyeavleald
|
|||||||||
subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 309-544 | 1e-59 | 196.8 | In-house | 40-284 (290) | alignment | ||
Range on Protein: 309-544
Range on HMM: 40-284/290.0
RERTRNMAAPKRSDNfsFVAVDTNRIRLS-ITNDIPCS-EYINASYIDSYNEAHEYIATQAPMENTINEFWQMVWEQKCTAIVMLTELQDRGQIESELYW
.. | . .|..| .| | ||| | |... |. |||||.||. |.|...|||||.|..||. .||...|..|.|.|||||. .. |. . ||
vgltssnkllnRfan..ivvyddnritLrpisghkDCtneyinAcyikgykekkqyiatqgpvsntlvdFWkliwqekvtiivmltniieegkvkCqqYW
PRDGCVRYGKYIVTKIDEEELDDHTQRSMD---------SLLVYHFQYHNWSAHGMPPRMNGLVFLHEQVQKIQSTEDHGPTVVHCSDGAGRTGVFLALA
| . .||.. .. ..||.|.. ..| .. . | ..| || .| . .. . . |...|.| . .. ||||||. ||..||.|.|
pdsdtkaygefsikllneetlneyierklevknknsagakqsvtqyqitnwdstgkvtnpqtillvieemyktqrkrgntsivvHCSdtvgrsavfcaaa
ISIERLEAEDTVDIFQTVRWLRSQRPALVGSIEQYSCCYQAVKSYLS
..|.. . | .|.|| .. .|.|.| .| . .|| .| | .||.
ttinkcktegvidvfqvlksqRiqkpgsvqtvqqyqgifqivltyld
|
|||||||||
subfamily_Cele-PTP-8_pd | Subfamily Cele-PTP-8 | 309-547 | 1.3e-28 | 94.9 | In-house | 46-275 (288) | alignment | ||
Range on Protein: 309-547
Range on HMM: 46-275/288.0
RERTRNMAAPkrsdnfsfvavDTNRIRLSitNDipCSEYINASYIDSYNEAHEYIATQAPMENTINEFWQMVWEQKCTAIVMLTELQDRGQIESELYWPR
|.| .|. |. |..|| .| . ||.| . | . . | .|||.. ||.|.|.|. |. ||||.|| ..|. .|. |.|
rdryenlprc...........ditrvkls..dd..pdfyiaanvvssakykrrlicaqaPlngtieelWkmllesdveyivmlcellekGkeksaeyfPs
D--GCVRYGKYI-VTKIDEEELDD-------HTQRSM-DSLLVYHFQYHNWSAHGMPPRMNGLVFLHEQVqkiqsTEDHGPTVVHCSDGAGRTGVFLALA
.|.|.. |.| . ...| . .. . .. .| . ...| .|.| . | | . . . | |||.| |.|||| .
klGekarigrlctvvkkkradidklvkvsllriskegeekvivkilhlleWdddgvPenylsplrllevl.....kslqkPivvhssaGvGrtgtlilil
ISIERLEAEDTVDIFQTVRWLRSQRPALVGSIEQYSCCYQAVKSYLSWRT
| .| | .| . | . . || .| . . || .. |. .| .
ialeslrlddflgirsllaklreerfkaiqtemqylyvhrcvleelllkk
|
|||||||||
subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 312-543 | 2e-43 | 143.3 | In-house | 33-277 (287) | alignment | ||
Range on Protein: 312-543
Range on HMM: 33-277/287.0
TRNMAAPKRSDNFSFVAVDTNRIRLSITNDIpCSEYINASYIDSYNEAHEYIATQAPMENTINEFWQMVWEQKCTAIVMLTELQDRGQIESELYWP-RDG
. ..|| |. . .| .|. || . . |.|||| |. ||.. ...||.|.|. |...||..|.|.. ......| . .. . ||| |.
aeelaavkknryadvlPiddtrvllsaegel.GsdyinanyvasytddeafiaaqgPiaatvrdfwravletrsasvitmtreveearlkcykywPerev
CVRYGKYIVTKIDEEELD-DHTQRSM--------DSLLVYHFQYHNWSAHGMPPRMNGLVFLHEQV-QKI---QSTEDHGPTVVHCSDGAGRTGVFLALA
.| | | |. .| . .. ... |.. .. .| ... .| .....| ||. . .| |.| ..... || |||.. |.||.|..||.
PmrvGGysvvlldydikePeygvralrlidletrearvvkqldllswPdkvlaPtavglirfvldvkqhielardasevGPlvvhddvGiGrsGillatl
ISIERLEAEDTVDIFQTVRWLRSQRPALVGSIEQYSCCYQAVKSYL
. ..||| ||. ..| || .| ||| .. |. |.|. .|
vlvsrledlGrvdvaavvirlreyraalvqavvqlrllyealvtyy
|
|||||||||
0047943 | (Phosphotyrosine protein) phosphatases II | 314-543 | 1.7e-71 | 236.2 | In-house | 35-272 (273) | alignment | ||
Range on Protein: 314-543
Range on HMM: 35-272/273.0
NMAAPKRSDNFSFVAVDTNRIRLsitnDIPCSEYINASYIDSYNEAHEYIATQAPMENTINEFWQMVWEQKCTAIVMLTELQDRGQIESELYWPRDG---
. .. . .....| .|..| . . | ||||||.| || ...||||.|..||...||.|||||... |||||||...|.. . ||| .|
lpenkdknrykdilpydhsrvkl....gdggsdyinAsyvdgynlkrkfiatqgPlpntvedfwrmvweqnvrviVmLtelvelgrekcaqYwpleggel
CVRYGKYIVTKIDEEELDDHTQRSM--------DSLLVYHFQYHNWSAHGMPPRMNGLVFLHEQVQKIQSTE-DHGPTVVHCSDGAGRTGVFLALAISIE
..|||..|| ..||. ||.|.| . .|. |.||.|..| || || .. |. . |.|.|.... ..||.|||||.| ||||.|.|| . ..
sltygkftvtllseetkddytvrtleltnlgtgesrtvthfhytgwpdhgvppslesllefielvrkalealpsngpvvVHCsaGvgRtgtfialdllld
RLEAEDTVDIFQTVRWLRSQRPALVGSIEQYSCCYQAVKSYL
.||.| .||....|..|||||| | . ||| .|.|. ||
qlekeggvdvleavkllrsqRpgmvqtpeqyrflyealleyl
|
|||||||||
subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 315-543 | 3.8e-63 | 208.4 | In-house | 44-283 (305) | alignment | ||
Range on Protein: 315-543
Range on HMM: 44-283/305.0
MAAPKRSDNFSFVAVDTNRIRLSITNDIPCSEYINASYIDSYNEAHEYIATQAPMENTINEFWQMVWEQKCTAIVMLTELQDRGQIESELYWPRDGCV--
| ... . . . |..||.|. ... . |.||||||.|.|.. ..||..|.|..||...||....| | . |||||.|.. |. . |||
eankaknrlkeitlldddriiltekeslddsdyinasyvdgykrkkkyivaqgPlkntvadfWrliveekvstivmltklveggkdkCrqYWpesktekk
RYGKYIVTKIDEEELDDHTQRSM---------DSLLVYHFQYHNWSAHGMPPRMNGLVFLHEQVQKIQSTEDHGPTVVHCSDGAGRTGVFLALAISIERL
..|...|. .|.. |...| . .| | ..| .| ||.| |. | ..||| |. . | .||||.| ||||||.|. | .|||
efgefsvelksektasdyieRklkisiededkesrtvlqyqltdWPdhGvpqfatsllslikrvqkdqkkdkgvpllVhCsagvgRtGvfiavdialerl
EAEDTVDIFQTVRWLRSQRPALVGSIEQYSCCYQAVKSYL
..|..||.|. .. |||.|. .| . .|| ...|.. ..
kkEevvdvfevlkqlRskrmkmvqtldqYvflhdaldeli
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 315-432 | 4.4e-19 | 63.3 | In-house | 37-147 (319) | alignment | ||
Range on Protein: 315-432
Range on HMM: 37-147/319.0
MaapkrsdnfsfVAVDTNRIRLSITNDIPCSEYINASYIDSYNEAH-EYIATQAPMENTINEFWQMVWEQKCTAIVMLTELQDRGQIESELYWPR----D
| . |. | | . .||..|||. |..|. |||.|...|.. .||..||||. || ||.|.. | |.| |
v...........vPlPetrvvlqrigdddkdeyldasyvrGyddapnsyiaaqvsledsssdfwrtvweqqsrvivqltdlselGikvcaeylPtketld
GCVRYGKYIVTKIDEeELDDHTQ
. ||.. || . | .|.
ntslyGdilvtlkgr.evkdrya
|
|||||||||
subfamily_PTPRG_pd | Subfamily PTPRG | 317-544 | 1.1e-60 | 200.4 | In-house | 47-288 (563) | alignment | ||
Range on Protein: 317-544
Range on HMM: 47-288/563.0
APKRSDNFSFVAVDTNRIRLSITNDIPCS-EYINASYIDSYNEAHEYIATQAPMENTINEFWQMVWEQKCTAIVMLTELQDRGQIESELYWPRDGCVRYG
.. . . ||.| |..|| . .. . .||||.||| |. ....|||| |...|.. ||.|.|||. . |||.|.|..||. . . |||.|. ..||
nkrKnRylnivaydrsRvklsplpgkkkklDYinAnyidGyqkskafiatqgplkdtfddFWrmiWeqnvaiivmitnlvergrrkcdvYWPkdesetyg
KYIVTKIDEEELDDHTQRSM--------------DSLLVYHFQYHNWSAHGMPPRM-NGLVFLHEQvqKIQSTEDHGPTVVHCSDGAGRTGVFLALAISI
. || |.|| | |.|.. . .||....| .| || | | | . . . .. ||.||||| |.||||....| .
alqvtlieeevlalytvrtlviknlklkkkkqcdteklvrqyhytkWPdhgvPehslpvLifvkks..saankaeaGPivvHcsaGvgrtGtyivldtll
ERLEAEDTVDIFQTVRWLRSQRPALVGSIEQYSCCYQAVKSYLS
.....|..|..|.... .|.||. || ..||| ..|. . ..
kqiqqenavnvfgflkhiraqRnflvqteEqYiflhdalleaia
|
|||||||||
subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 318-544 | 5.7e-73 | 240.7 | In-house | 48-284 (319) | alignment | ||
Range on Protein: 318-544
Range on HMM: 48-284/319.0
PKRSDNFS-FVAVDTNRIRLSITNDIPCSEYINASYIDSYNEAHEYIATQAPMENTINEFWQMVWEQKCTAIVMLTELQDRGQIESELYWPRDGCVRYGK
|. . .. .|.| |. || .... |.|||||.||.|.| ...||||||.||||..||.||||... .||||.|....... . |||. ..||.
nkkknryqnilaydrtrvvlseldgvegsdyinasfidgyqerekfiatqaPlentiedfWrmvWeeessivvmltklveklkvklkkywpeenfeeyGr
YIVTKIDEEELDDHTQRS---------MDSLLVYHFQYHNWSAHGMPPRMNGLVFLHEQVQKIQSTEDHGPTVVHCSDGAGRTGVFLALAISIERLEAED
.||| .||||.| | ... | |||| .|. |..| . .|. | ....| .. ...|| |||||.|.|||| |..| . .||.. |
livtleeeeeledyiirklklnkkssevetRevkhfqyteWpdhdvPekatslldllkrirksrektqsgPivvhCsaGvGRtGtfivldamlervkeeg
TVDIFQTVRWLRSQRPALVGSIEQYSCCYQAVKSYLS
..|.|.||. || ||. .| |||. .|.|. ...
vlDvfstvsrlRtqRnimvqrpeqYkfiyealleave
|
|||||||||
subfamily_PTPN14_pd | Subfamily PTPN14 | 318-544 | 3.7e-48 | 159.1 | In-house | 50-297 (300) | alignment | ||
Range on Protein: 318-544
Range on HMM: 50-297/300.0
PKRSDNFSFVAVDTNRIRLSITNDIpCSEYINASYIDSY--NEAHEYIATQAPMENTINEFWQMVWEQKCTAIVMLTELQDRGQIESELYWPRD----GC
... .. . ||..|| |.. ..||||| | . ..||..|.|.|.|...||||||||. . |||||| .. |. | |.|..
aeknrfkdvlPyednrvelsptken.stgyinassikvsvggkersyivaqgPleltvqdfWqmvWeqgvqlivmlteeeedgkeksfkyfPkleskkkt
VRYGKYIVTKIDEEELDD--------HTQRSMDSLLVYHFQYHNWSAHGMPPRMNGLVFLHEQVQKIQ--------STEDHGPTVVHCSDGAGRTGVFLA
|..||. ||. |. | . | . |.|.|| .|. ||.|. ..| . |.|| .. |.| . | .||||.|.||||| .
vefgkfkvttkfsedsdsvittglklkhlpskeertvwhlqytDWpdhgvPeDvkgflsyLeevqsvrrktnseveskeskPPvlvhCsaGvGrtGvlil
LAISIERLEAEDTVDIFQTVRWLRSQRPALVGSIEQYSCCYQAVKSYLS
. |. || ....|| .... || || || .. || |... ||
sdlliatlehneeidikkvlarLreqrmllvqtlaqYkfvYkvlikylk
|
|||||||||
subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 319-541 | 6.7e-57 | 187.8 | In-house | 51-278 (315) | alignment | ||
Range on Protein: 319-541
Range on HMM: 51-278/315.0
KRSDNFSFVAVDTNRIRLSITNDIPCSEYINASYIDSYNEAHEYIATQAPMENTINEFWQMVWEQKCTAIVMLTELQDRGQIESELYWPRDgCVRYGKYI
.. . .| | |..| ... | |.|.||..|| || . |||.|.| .....||..|.|.... |||||.| .. . .| ||| . | |||.
qknryiniiaydksrvqlpllendphsdyvnanfidGynkkrryiaaqgpnvasvkdfwrlvfeedigkivmltnlvegekrkaekywpdk.kviyGkit
VTKIDEEELDDHTQRSMDSL------LVYHFQYHNWSAHGMPPRMNGLVFLHEQVQKIQsTEDHGPTVVHCSDGAGRTGVFLALAISIERLEAEDTVDIF
||...|| .. | |.. |. ..| | |.| |. |. .|.. . |.. |. |||||.| |||| |..| ....|||. .|..
vtrkseevnteytvrtlsvvfgdnirevvqlhytswpdmgvpkytiplmnlirtvkqhh.tnsvgaivvhcsaGvGrtGtfitldavldqaeaenaidvy
QTVRWLRSQRPALVGSIEQYSCCYQAV-KS
. .. .|..| .| ..||| |.|. ..
nfitgvrqnrikmvqvaeqyqfiydallet
|
|||||||||
subfamily_CG7180_pd | Subfamily CG7180 | 319-542 | 1.9e-53 | 176.0 | In-house | 44-289 (296) | alignment | ||
Range on Protein: 319-542
Range on HMM: 44-289/296.0
KRSDNFSFVAVDTNRIRLSITNDIPCSEYINASYIDSYNEAHEYIATQAPMENTINEFWQMVWEQKCTAIVMLTELQDRGQiESELYWPRDGCVRYGKYI
.. . | | ||. |. . |.||||.|.||. .||| |.||...|..|||..|..... |.|.||. | . ||| .. .||. .
eknrdvkvvPyDynRvvLekldGeeksdYinavyvdsflkkkeyivteapkketvdefWrlvydeeisavvvLtktfdfak.mypsywpnkskeqygeif
VTKIDEEELDDH------------------TQRSMDSLLVYHFQYHNWSA-HGMPPRMNGLVFLHEQVQKIQSTE----DHGPTVVHCSDGAGRTGVFLA
| . |... . .| ... .| .||. | . .| |.|. | ..|.... ..||.||..||||.|.||.||
veiveekqyanlkirtfkltkkivalteqekqvkaetRivklfqlteWeledkvPlstnalielrrrvrlwrekvdedpeegPvvvvssdGasRsGvyla
LAISIERLEAEDTVDIFQTVRWLRSQRPALVGSIEQYSCCYQAVKSY
. ...| .| |. ||.|. |. || .|| || ..|.| .|. .. .
idanlelvekeeevdvFeavktlrrsRpqLvenveeYkyiYdvllea
|
|||||||||
subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 319-544 | 1.4e-48 | 160.7 | In-house | 52-290 (325) | alignment | ||
Range on Protein: 319-544
Range on HMM: 52-290/325.0
KRSDNfsFVAVDTNRIRLSITNDIPCSEYINASYIDSYNEAHEYIATQAPMENTINEFWQMVWEQKCTAIVMLTELqDRGQIESELYWPRD--GCVRYGK
| | ||.| .|. | .| | |.||||||. .. . . ..|.|||. .|||..|..| . .|. .|.| || | |. . |||.. ...|
nrfkn..vvaldksrvvletkkddpssdyinasylrddkkkdvflaaqaPltatindlWrlvldWrcsvvvvlnel.dlgkdrcavywpkemgksktfGg
YIVTKIDEEELDDHTQRSMD--------SLLVYHFQYHNWSAHGMPPRMNGLVFLHEQVQKI----QS-TEDHGPTVVHCSDGAGRTGVFLALAISIERL
| . ||. |. .| .| .. | ||. | | . | |. . . |... .. |. .| .||||.| ||||||..| ....
levklrtieeisdyvhrvldvkqvkkGetrsvkqfqlqswddmGvqkrpatlisilqlvkavservtantkastpilvhcsaGvGrtGvfislysalakv
EAEDTVDIFQTVRWLRSQRPALVGSIEQYSCCYQAVKSYL-S
| ||||. |. || .||..| ...||. .|.|. .. |
ieesrvdifgfvkklrkdrpsmvetvdqyiliyealveayms
|
|||||||||
subfamily_eak_pd | Subfamily eak | 319-462 | 1.1e-16 | 55.2 | In-house | 54-202 (332) | alignment | ||
Range on Protein: 319-462
Range on HMM: 54-202/332.0
KRSdNFSFVAVDTNRIRLSITNDIPcSEYINASYIDSYNEAHEYIATQAPMENTINEFWQMVWEQKCTAIVMLTELQDRGQIESELYWPRDG--CVRYGK
.| . | | . .||. . . ||||| .. . ..|| | .. |. . ||||| ||| |||.| | . . .|. |.| .. ...|.
nrn.vvkivpydrylvrltssqlnr.lGyinaslaefsevGrkyiltGiasedkvfafwqmvleqkspaivqlledvelkleksdkyfpdktreelkfGi
YIVTK---IDEEELDDH---TQRSMDSLLVYHFQYHNWSAHGMPpRMNGLVF
. |.. . .. |. .. .. |.|.... |. .| ... ..
ldverkefvkrniletrllelskGnethrvlhykvfGwtettlp.kyedfla
|
|||||||||
subfamily_Cele-PTP-17_pd | Subfamily Cele-PTP-17 | 319-401 | 5.6e-12 | 39.8 | In-house | 47-126 (347) | alignment | ||
Range on Protein: 319-401
Range on HMM: 47-126/347.0
KRSDNFSFVAVdTNRIRLSITNDipCSEYINASYIDSYNEAHEYIATQAPMENTINEFWQMVWEQKCTAIVMLTELQDRGQIE
| |. | .. . | ..| |||||.| | .||| || |. .|. .||.|| | | .| . | . ||
klidatrvvls.peksknsradd..vetyinashikfdnaskeyiltqyplpdtvrdfwkmvsvtkvtqvvtifepikdeaie
|
|||||||||
subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 320-545 | 1.9e-60 | 199.2 | In-house | 12-244 (250) | alignment | ||
Range on Protein: 320-545
Range on HMM: 12-244/250.0
RSDNFSFVAVDTNRIRLSITNDIPCSEYINASYIDSYNEAHEYIATQAPMENTINEFWQMVWEQKCTAIVMLTELQDRGQIeSELYWPRDGCVRYGKYIV
. ..|.| |. | .. |.|||||....|.| . .||||.|...||..||.||.|.| ..|||||.|.. .. . ||| .. .||. |
knryadiialdssrvvLekekgdkesdyinasflhgyderkafiatqgPlqatiedfWrmvleeksgtivmLtnLkesekt.yhqywPvekaekyGdvtv
TKIDEEELDDHTQRSM--------DSLLVYHFQYHNWSAHGMPPRMNGLVFLHEQVQKIQSTEDHGPTVVHCSDGAGRTGVFLALAISIERLEAEDTVDI
. ..|| | |.| . |. .| .... .| |.| .. . | ..||. | . .| .|.|| | ||.| |.|. .|||. | .||.
sllskeefadytkrklklskakkaderivrqlhfvvWPdkgvPevatavLellkkvqasqqqagnaPvivqCsaGvgrsGafiaidavlerlkkekvvdv
FQTVRWLRSQRPALVGSIEQYSCCYQAVKSYLSW
|. .. || .|| | | |||. .|.... .|
fkvikvlrkdrphavesleqyvfvyeiilkalds
|
|||||||||
subfamily_PTPRN_pd | Subfamily PTPRN | 320-540 | 5e-42 | 138.6 | In-house | 59-289 (297) | alignment | ||
Range on Protein: 320-540
Range on HMM: 59-289/297.0
RSDNFSFVAVDTNRIRLSITNDIPCSEYINASYI-DSYNEAHEYIATQAPMENTINEFWQMVWEQKCTAIVMLTELQDRGQIESELYWPRDGCVRYGKYI
. . .... | .|..|. ... |.||||| | |. | |||||.|. .|. .|||||||| .. ||.||.|.. | . . ||| .| |. |
knrskavlpydhsrvklkeeasaeksdyinasaildhdprapayiatqgplastvadfwqmvweqGvvvivnltrleeegvkqckrywpdeGsevyhiye
VTKIDEEE-LDDHTQRSM--------DSLLVYHFQYHNWSAHGMPPRMNGLVFLHEQVQKIQSTeDHGPTVVHCSDGAGRTGVFLALAISIERLE-AEDT
| . | ||. ||. .. | | . | ..|.|. . |. . .|.| | |||||||||||||.... . ..||
vhlvsehiwcddylvrsfylknlqtsetrtvtqfhflswpeegvPasaksllefrrkvnksyrG.rscpivvhcsdGaGrtGvyilidlvlnrllkGvke
VDIFQTVRWLRSQRPALVGSIEQYSCCYQAVK
.|| |. || ||| || . .|. ...||
idiaatlehlrdqrpglvktkdqfefaltava
|
|||||||||
subfamily_Cele-PTP-4_pd | Subfamily Cele-PTP-4 | 320-544 | 3.4e-25 | 83.1 | In-house | 56-286 (302) | alignment | ||
Range on Protein: 320-544
Range on HMM: 56-286/302.0
RSDNFSfvAVDTNRIRLSITNDipcsEYINASYIDSYNEAHEYIATQAPMENTI---NEFWQMVWEQKCTAIVMLTELQDRGQIESElYWP--RDGCVRY
.|... ..|.|...|. ..| .|.||| .. . .. | .| | .. .|||.||...|.. .|.| .. . || ..| . . |
qsedvp..ildsnlvkleaepd....syvnaskvevPeltrsiilaQlpkvdsedsveeFWrmvfqekivsvvilvgeeelkktlse.lfpkksgdykey
GKYIVTKIDEEELDDHT---------QRSMDSLLVYHFQYHNWSAHGMPPRMNGLVFLHEQVqKIQSTEDHGPTVVHCSDGAGRTGVFLALAISIERLEA
|| | . |. .... . .|.|. .|| .. .| ... |. ..| .... .||. |||| |.||.||...|.|..
gkmfvNnrkVekaeeektryviEvlPegcsnsvlanvyvltnWkqkkvpvkyaeliktaakv.fakkikadentvivSknGaGRagafltlavaveklqk
EDTVDIFQTVRWLRSQRPALVGSIEQYSCCYQAVKSYLS
.. . | ..|. .|||||. | |..|| | |. |.
gkepnikeivksiRsqRpravdslkQyvslyialllyik
|
|||||||||
0036941 | (Phosphotyrosine protein) phosphatases II | 322-546 | 6.5e-72 | 237.6 | In-house | 47-280 (297) | alignment | ||
Range on Protein: 322-546
Range on HMM: 47-280/297.0
DnfsFVAVDTNRIRLsitNDiPCSEYINASYIDSYNEAHEYIATQAPMENTINEFWQMVWEQKCTAIVMLTELQDRGQIESELYWPRD--GCVRYGKYIV
| ... | .|..| .| . | ||||||.| |. ...||||.|..||...||.|||||..| ||||||| ..| . . ||| . . . ||...|
d...ilpydhtRVkl...dd.egsdYinAsyvdgydlkrkfIatqgPlpntvedFWrmvweqnvtvIvmltelvelgrekcaqywpleegesltygdftv
TKIDEEE--LDDHTQR--------SMDSLLVYHFQYHNWSAHGMPPRMNGLVFLHEQVQKIQSTE-DHGPTVVHCSDGAGRTGVFLALAISIERLE---A
| ...|. ||| |.| . .|. |.||.|..| ||.|. .. |. . |.|.|... ..||..||||.| ||.|.|.|. . ...||
tllsvevvllddytlrtlevtdtgngesrtvthfhytgwpdhgvpespaslldfielvrkvlkllpsggpvlVHCsaGvgRsgtfiaadlmlqqledklk
EDTVDIFQTVRWLRSQRPALVGSIEQYSCCYQAVKSYLSWR
| .|||...|..||.||| | . ||| .|.|. .| ..
eggvdileavkklReqRpgavqtleqyrflyeallellkkk
|
|||||||||
subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 322-541 | 3.5e-63 | 208.3 | In-house | 52-277 (288) | alignment | ||
Range on Protein: 322-541
Range on HMM: 52-277/288.0
DNFSFVAVDTNRIRLSITNDIPCSEYINASYIDSYNEAHEYIATQAPMENTINEFWQMVWEQKCTAIVMLTELQDRGQIESELYWPRDGC-VRYGKYIVT
...| .|..| .. . ..||||||||.... ..|||||.|. .|.|.||..|.|.| . ||||||| ..|. . | ||| .. ..||. ||
RyrnilpyDekrvklkkleeeagaDYinasyidgekkkkkyiatqgPladtvndfWelvyenktstivmltelveggktkCeeYWPdadkpknyGsvtvt
KIDEEELDDHTQRS------MDSLLVYHFQYHNWSAHGMPPRMNGLVFLHEQVQkIQSTEDHGPTVVHCSDGAGRTGVFLALAISIERLEAEDTVDIFQT
....||.|...|. .. | . ..|| |. ||.| . |. | .||. .....| || .||||.| ||||.|.|| |...|.||..|.. |
lveskeledfvlrklllekkkteleitqyqylaWpdhgvPeskapllellrqvk.vanqadtgpiivhCsaGvGrtgtFialdalidaveeedyiDvagt
VRWLRSQRPALVGSIEQYSCCYQAVKS
| || ||. || .|| .|... |
vaklRkqRallvqtlkqYefiyevlls
|
|||||||||
subfamily_PTPRK_pd | Subfamily PTPRK | 322-539 | 6.7e-63 | 207.4 | In-house | 48-273 (314) | alignment | ||
Range on Protein: 322-539
Range on HMM: 48-273/314.0
DNFSFVAVDTNRIRLSITNDIPCSEYINASYIDSYNEAHEYIATQAPMENTINEFWQMVWEQKCTAIVMLTELQDRGQIESELYWPRDGCVrYGKYIVTK
.| | |..| ... | |.||||..||||. ....|.|| |...|...||..|....|..|||||||.. |... ||| |. | ||. |.
rsgdilaydrsrvflitidgdpssdyinaalidsykrpaafivtqgPlqetvkdfWrlvydencasivmltelvevgrvkClkyWPedtev.ygdikvel
IDEEELDDHTQRS----------MDSLLVYHFQYHNWSAHGMPPRMNGLVFLHEQVQKIQSTeDHGPTVVHCSDGAGRTGVFLALAISIERLEAEDTVDI
.. | | . .| . .| .||. .|..|..| .||. | .|.| | ..|..||||| ||||||.|.|..| .. .| |..||.
vetellaelvvrifrveklargqeeirevrqfqflgWpdhdvPvsatgllklvrrvkksqee.eaGrivvhCsaGaGrtGtfiaidivldmieregvvdv
FQTVRWLRSQRPALVGSIEQYSCCYQAV
|..|. |||... .| ||| .|...
fnavktlrsrkvnmveteeqykfiydvi
|
|||||||||
0037934 | (Phosphotyrosine protein) phosphatases II | 322-542 | 9.7e-59 | 194.2 | In-house | 15-241 (243) | alignment | ||
Range on Protein: 322-542
Range on HMM: 15-241/243.0
DNFSFVAVDTNRIRLsitNDipcSEYINASYIDSYNeahEYIATQAPMENTINE----FWQMVWEQKCTAIVMLTELQDRGQIESELYWPrDGCvRYGKY
.... | .|..| .. | ||||..|. .. .||||.|...|... ||.|.||...|.|||||||...|.. . ||| .. .||..
rysdilpydhsrvkl...eg...sdyinanliyvtp...rliatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqywp.gev.tygdf
IVTKIDEEELDDHTQR---------SMDSLLVYHFQYHNWSAHGMPPRMNGLVFLHEQVQKIQST-------EDHGPTVVHCSDGAGRTGVFLALAISIE
.|| ..||.||| |.| . ..||.|..|..| ||.|. .. |. ....|..... ..||..|||| | ||||...|. . ..
tvtllseehlddytvrtlllenldlddltrlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgRtGtliaaylmll
RLeaedTVDIFQTVRWLRSQRPA-LVGSIEQYSCCYQAVKSY
.| .||....|..||.||| | . .|| .|.|.. .
ll....gvdleeavkllreqRpgkavqtpsqyrflyeallel
|
|||||||||
0050432 | (Phosphotyrosine protein) phosphatases II | 323-545 | 1.8e-75 | 249.4 | In-house | 74-301 (308) | alignment | ||
Range on Protein: 323-545
Range on HMM: 74-301/308.0
NFSFVAVDTNRIRLsitnDiPCSEYINASYIDSY--NEAHEYIATQAPMENTINEFWQMVWEQKCTAIVMLTELQDRGQIESELYWPRD---GCVRYGKY
.... | .|..| | . | ||||||.| | . ...||||.|..||.. ||.|||||... |||||.|...|.. . ||| . |...|||.
ykdilpydhsRVkl....d.egsdYInAsyvdgyssklprkfIatqgPlpntvedFwrmvweqnvrvIvmLtklvengrekcaqYwplelgggsleygkf
IVTKIDEEELDDHTQR--------SMDSLLVYHFQYHNWSAHGMPPRMNGLVFLHEQVQKIQsteDHGPTVVHCSDGAGRTGVFLALAISIERLEAEDTV
|| ..||.|||.|.| . .|. |.||.|.|| || || .. |. . |.|.| . ..||.|||||.| ||||.|.|| . .|.||.| .|
tvtllseevlddytvrtleltnlgdgesrtvthfhytnWpdhgvPpspeilldflelvrksl...pggpivVHCsaGvGRtGtfialdllleqlekeggv
DIFQTVRWLRSQRPALVGSIEQYSCCYQAVKSYLSW
|.|..|..||.||| | . ||| .|.|. ||..
dvfeavkklReqRpgmvqtpeqylflyralleylkl
|
|||||||||
0043336 | (Phosphotyrosine protein) phosphatases II | 323-542 | 4e-70 | 231.8 | In-house | 51-276 (278) | alignment | ||
Range on Protein: 323-542
Range on HMM: 51-276/278.0
NFSFVAVDTNRIRLSITNDIPCSEYINASYIDSYNEAHEYIATQAPMENTINEFWQMVWEQKCTAIVMLTELQDRGQIESELYWPrDGCVRYGKYIVTKI
.... | .|..|| .. . | ||||||.| || ...||||.|...|.. ||.||||...| ||||||| ..|.. . ||| .| ..||.. || .
ykdilpydhsrvklsllggdldsdYinAsyvdgynvprkfiatqgPlpetvedFwrmvwelgvttivmLtelvelgrvkcaqYwp.ggsltygdftvtll
DEEELDDHTQRSM--------DSLLVYHFQYHNWSAHGMPPRMNGLVFLHEQVQKIQStEDHGPTVVHCSDGAGRTGVFLALAISIERLEAEDTVDIFQT
.||.||| |.| . |. |.|..|..| || |. .. |. . ..|..... ..||..||||.| ||||.|.|| . .|.|| | .||....
keehlddytvrtlevtnlgdgesrtvthyhylgwpdhgvpeslsllldflkavreale.dsngpvlVHCsaGvgRTGtfialyllleqlekeggvdleea
VRWLRSQRPALVGSIEQYSCCYQAVKSY
|..||.||| | . .|| .|.|.. |
vkelreqRpgavqtpsqyrflyealley
|
|||||||||
0039614 | (Phosphotyrosine protein) phosphatases II | 323-545 | 3.3e-69 | 228.9 | In-house | 62-291 (297) | alignment | ||
Range on Protein: 323-545
Range on HMM: 62-291/297.0
NFSFVAVDTNRIRLSITNDI-PCSEYINASYIDSYNE-AHEYIATQAPMENTINEFWQMVWEQKCTAIVMLTELQDRGQiESELYWPRDGCvRYGKYIVT
.... | .|..|. .. . | ||||||.| |. ...||||.|...|.. ||.|||||..|.|||||.| ..|. . ||| .| .||.. ||
ykdilpydhsrvklkpedgvdldsdYinAsyvdgydlltrkfIatqgPlpetvedFwrmvweqgvtvivmLtklvelgr.kcaqywpeegg.tygdftvt
KIDEEELDDHTQRSM------DSLLVYHFQYHNWSAHGMPPRMNGLVFLHEQVQKIQSTE-DHGPTVVHCSDGAGRTGVFLALAISIERLEAEDTVDIFQ
...|.||. |.| . |. |.||||..| || || .. | . |.|...... ..||..||||.| ||||.|.|. . .|.|| | .||...
llkvehldgytvrtlevtnngesrtvthfqytgwpdhgvppslellleflelvrealaelpkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvle
TVRWLRSQRPALVGSIEQYSCCYQAVKSYLSW
.|..||.||| | . .|| .|.|.. .|..
avkelreqRpgavqtpsqyrflydallellkr
|
|||||||||
0046845 | (Phosphotyrosine protein) phosphatases II | 324-546 | 1.6e-73 | 242.9 | In-house | 35-277 (284) | alignment | ||
Range on Protein: 324-546
Range on HMM: 35-277/284.0
FSFVAVDTNRIRLSITND-IPCSEYINASYIDSY-----NEAHEYIATQAPMENTINEFWQMVWEQKCTAIVMLTELQDRGQIESELYWPRDG-CVRYGK
.... | .|..|. ... .. |.||||||.| | . ...||||.|..||...||.|||||... ||||||| ..|.. . ||| .| ...||.
kdilpydhsRVklksldgdledsdYinAsyvdgydldltyikkkfIatqgPlpntvedFwrmvweqnvrvIVmltelvengrekcaqYwplegevltygd
YIVTKIDEEELDDHTQR---------SMDSLLVYHFQYHNWSAHGMPPRMNGLVFLHEQVQKIQST-EDHGPTVVHCSDGAGRTGVFLALAISIERLEAE
..|| ..||. ||.|.| . |. |.||.|..| || || .. |. . ..|..... ...||.|||||.| ||||.|.|| . .|.||.|
ftvtllseevkddytvrtleltnlgytgesrtvthfhytswpdhgvppspedlleflrlvrellenlpgggpivVHCsaGvgRtGtfialdllleqleke
D---TVDIFQTVRWLRSQRPALVGSIEQYSCCYQAVKSYLSWR
. .||....|..||.||| | . ||| .|.|. ||...
glllgvdvleavkrlreqRpgmvqtleqyrfvyealleylklk
|
|||||||||
0040438 | (Phosphotyrosine protein) phosphatases II | 324-546 | 1.1e-72 | 240.3 | In-house | 50-279 (317) | alignment | ||
Range on Protein: 324-546
Range on HMM: 50-279/317.0
FSFVAVDTNRIRLSITNDIPCSEYINASYIDSYNEAHEYIATQAPMENTINEFWQMVWEQKCTAIVMLTELQDRGQIESELYWPRDGCVRYGKYIVTKID
... | .|..|| .. .. | ||||||.| .|. ...||||.|..||.. ||.|||||..| ||||||| ..|.. .. ||| .. . ||...|| ..
pdilpydhsRVkLsplggdldsdYInAsyvdgpnlkrkfIatqgPlpntvedFwrmvweqgvtvivmLteleelgrekcaqYwplgetltygdftvtlls
EEELDDHTQRSM--------DSLLVYHFQYHNWSAHGMPPRMNGLVFLHEQVQKIQStEDHGPTVVHCSDGAGRTGVFLALAISIERLEAEDTVDIFQTV
||||.. | | . .|. |.||.|..| || || .. |. . |.|.. .. ...||..||||.| ||||.|.|. . .|.|| | .||....|
eeelagitlrtlevedlgdsesrtvthfhytgWpdhgvppspdllldfleavreale.dpggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdveeav
RWLRSQRPALVGSIEQYSCCYQAVKSYLSWR
..||.||| | . ||| .|.|. || ..
kelreqRpgavqtpeqyrflydalleylkrk
|
|||||||||
0042113 | (Phosphotyrosine protein) phosphatases II | 324-543 | 3.4e-65 | 215.2 | In-house | 16-243 (245) | alignment | ||
Range on Protein: 324-543
Range on HMM: 16-243/245.0
FSFVAVDTNRIRLSITNDIPCSEYINASYIDSYNEAHEYIATQAPMENTINEFWQMVWEQKCTAIVMLTELQDRGQIESELYWPRDGCVRYGKYIVTKID
.... | .|..|| .. . | ||||||.| |. . .||||.|...|.. ||.|.||...|.||||||. ..|.. .. ||| .. ..||...|| ..
sdilpydhtrvklspdggdldsdyinasyvdgyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywplgesltygdftvtlls
EEELDDHTQ--------RSMDSLLVYHFQYHNWSAHGMPPRMNGLVFLHEQVQKIQSTEDHGPTVVHCSDGAGRTGVFLALAISIERLEAEDTVDIFQTV
|| ||| |. .. |. |.|..|..| ||.|. .. |. ..| |.|... ..||..||||.| ||||.|.|. . .|.||.| .|.....|
eehlddytvrtlevtnlgddesrevihyhylpwpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylmleqlekelgvsleeav
RWLRSQRPALVGSIEQYSCCYQAVKSYL
..|||||| | . .|| .|.|.. .|
kelrsqRpgavqtpsqyrflyeallell
|
|||||||||
subfamily_PTPN23_pd | Subfamily PTPN23 | 324-540 | 1.4e-42 | 140.5 | In-house | 50-277 (288) | alignment | ||
Range on Protein: 324-540
Range on HMM: 50-277/288.0
FSFVAVDTNRIRLSITNDipcsEYINASYIDSY-NEAHEYIATQAPMENTINEFWQMVWEQKCTAIVMLTELQDRGQIESELYWPR--DGCVRYGKYIVT
. | ||. | ..| .|||||.. . . ..||||||...|.|.||.||.||| ||||.. ...|. . . ||| . |..|.. ||
rdilPyDhnRvklrgskD....DYinAsfvkdlspgcPdfiatqaPlqstlnDFWlmvyeqkssviVmllskeelgkpkvdrYwPedkgetvkfgdlsvt
KIDEEELDDHTQRSMD--------SLLVYHFQYHNWSAHGMPPRMNGLVFLHEQVQK---IQSTEDHGPTVVHCSDGAGRTGVFLALAISIERLEAEDT-
...|.. | .| . | | |...|. .|.| . |. . ..|.. . . . | ||||| | |||||| . .. ||...
lksvretethvervlkletldadavksvshlqltsWpelGvPasPetllqfldevesayeavqrksktPlvvhCsaGvgRtgvfalvyaavrelekgngl
VDIFQTVRWLRSQRPALVGSIEQYSCCYQAVK
.|| | |. || || | ||. .|.||
ldiiqvvsrlreqRrfmvqekeqlkfsyeavl
|
|||||||||
subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 324-540 | 3.1e-32 | 106.6 | In-house | 40-292 (297) | alignment | ||
Range on Protein: 324-540
Range on HMM: 40-292/297.0
FSFVAVDTNRIRLSitNDIPCSEYINASYIDSYNEAHE--YIATQAPMENTINEFWQMVWEQKCTAIVMLTELQDRGQIESELYWPR--DGCVRYGKYIV
.|.|..|..| . |. ..|||| |. .| .. || .| |...|...||..|.|| .|||...||. |. |||. .. . |...|
rdilatddtrvkll..rviterdyinadyvvfpdeeadlkyilaqGplsatvddfwtlvaeqdvrvivmvaklqedGrdkcapywpsvvqerlkagdvvv
TKIDEEElDDHTQRS---------MDSLLVYHFQYHNWSAHGMP--------------------PRMNGLVF-----LHEQVQKIQSTED-HGPTVVHCS
. . |.. . .| | | |. .| ||.| | | .|| . |.. ... ...||||
eflssts.defdrviltelqliyrsesrvvrhvqflswpdhGvpsdledlvrfqaqvcscciavpmmlalvemftamvflqleslraemprnayllvhcs
DGAGRTGVFLALAISIERLEAEDTVDIFQTVRWLRSQRPALVGSIEQYSCCYQAVK
| ||.|| . . ...| . |. .. ||.||. || ..||. .|.||
aGvGrsGvvvlsdvilaklrkkripdvaailsilreqrarlvqtleqfellydavl
|
|||||||||
subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 325-544 | 1.1e-70 | 233.3 | In-house | 54-281 (318) | alignment | ||
Range on Protein: 325-544
Range on HMM: 54-281/318.0
SFVAVDTNRIRLSITNDIPCSEYINASYIDSYNEAHEYIATQAPMENTINEFWQMVWEQKCTAIVMLTELQDRGQIESELYWPRDGCVRYGKYIVTKIDE
.| |. |..|. ... . |.||||.||| |.. ..|||.|||. .||..||.|||||... |||||....||.. . ||| .| ||| |. .|
nilaydhtrvkLqmlegeegsDyinanyidGyrrkkayiaaqaPlpetieDfWrmvWeqnsavivmltqeeergkakvhryWPskgsrsygklvvelkee
EELDDHTQRSM--------DSLLVYHFQYHNWSAHGMPPRMNGLVFLHEQVQKIQSTEDHGPTVVHCSDGAGRTGVFLALAISIERLEAEDTVDIFQTVR
||.|.. |.. .| | ..| .|. .|.| .|. | ||.|.| ....||.||||| | ||||||.|. | .||..|| .||.||||.
velsdyvlrefkvtrteeeesrqvrqyhytsWpdegvpesgaslldlvrqvskaqqksgagpivvhCsaGvGrtGvfiavdillerikaealvDvfqtvk
WLRSQRPALVGSIEQYSCCYQAVKSYLS
||.||...| .|| .|.... .|
qlreqrnlmvqtedqyefiydvlleala
|
|||||||||
DSPc_SM00195 | 325-543 | 3.2e-67 | 222.0 | In-house | 34-262 (263) | alignment | |||
Range on Protein: 325-543
Range on HMM: 34-262/263.0
SFVAVDTNRIRLSITNDIPCSEYINASYIDSYNEAHEYIATQAPMENTINEFWQMVWEQKCTAIVMLTELQDRGQIESELYWPRD--GCVRYGKYIVTKI
.. .| .|..|. ... . |.||||.||. .|. ..|||||.|...|...||.||||.|.. |||||| ...|... . |||.. | ..||. |. .
nilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivmlteeeengkekcdrywpeesggketfgkisvklv
DEEELD-DHTQRSM--------DSLLVYHFQYHNWSAHGMPPRMNGLVFLHEQVQKIQSTEdHGPTVVHCSDGAGRTGVFLALAISIERLEAEDTVDIFQ
..|. . . ..| . .. |...||.|| ||.| .. .. | ..|.| .||. .||.|||||.| ||||.|... | ...||.|..||||.
evekkkdeiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkksksts.sgpivVhCsaGvgRtgtfvtidiilskleeekkvdife
TVRWLRSQRPALVGSIEQYSCCYQAVKSYL
.|. ||.||| .| . |||. .|.|. |.
ivkelRkqRpgmvqtleqYlfiyeaileyi
|
|||||||||
PTPc_SM00194 | 325-543 | 3.2e-67 | 222.0 | In-house | 34-262 (263) | alignment | |||
Range on Protein: 325-543
Range on HMM: 34-262/263.0
SFVAVDTNRIRLSITNDIPCSEYINASYIDSYNEAHEYIATQAPMENTINEFWQMVWEQKCTAIVMLTELQDRGQIESELYWPRD--GCVRYGKYIVTKI
.. .| .|..|. ... . |.||||.||. .|. ..|||||.|...|...||.||||.|.. |||||| ...|... . |||.. | ..||. |. .
nilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivmlteeeengkekcdrywpeesggketfgkisvklv
DEEELD-DHTQRSM--------DSLLVYHFQYHNWSAHGMPPRMNGLVFLHEQVQKIQSTEdHGPTVVHCSDGAGRTGVFLALAISIERLEAEDTVDIFQ
..|. . . ..| . .. |...||.|| ||.| .. .. | ..|.| .||. .||.|||||.| ||||.|... | ...||.|..||||.
evekkkdeiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkksksts.sgpivVhCsaGvgRtgtfvtidiilskleeekkvdife
TVRWLRSQRPALVGSIEQYSCCYQAVKSYL
.|. ||.||| .| . |||. .|.|. |.
ivkelRkqRpgmvqtleqYlfiyeaileyi
|
|||||||||
0040439 | (Phosphotyrosine protein) phosphatases II | 325-543 | 4e-67 | 221.7 | In-house | 19-246 (249) | alignment | ||
Range on Protein: 325-543
Range on HMM: 19-246/249.0
SFVAVDTNRIRLSITNDIPCSEYINASYIDSYNEAHEYIATQAPMENTINEFWQMVWEQKCTAIVMLTELQDRGQIESELYWPRDGCVRYGKYIVTKIDE
.... | .|..|||... ..| |||||||| |. ...||||.|...|.. ||.|.||...|.|||||.|. .|.. . ||| .| . ||.. || ...
dilpydhsrvklsilpglflsdyinAsyidgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqywplggsleygdftvtllsv
EELDDHTQ--------RSMDSLLVYHFQYHNWSAHGMPPRMNGLVFLHEQVQKIQSTE-DHGPTVVHCSDGAGRTGVFLALAISIERLEAEDTVDIFQTV
|..|| |. .|. |.|.||..| || || .. |. . |.|.|.... ..||..||||.| ||||.|.|. . .|.|| | .||....|
evkddytvrtleltnlydgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtfiaaylmleqlekelgvdleeav
RWLRSQRPALVGSIEQYSCCYQAVKSYL
..|||||| | . ||| .|.|.. .|
kllrsqRpgavqnpeqyrflyeallell
|
|||||||||
subfamily_PTPRB_pd | Subfamily PTPRB | 325-545 | 1.9e-63 | 209.3 | In-house | 59-287 (293) | alignment | ||
Range on Protein: 325-545
Range on HMM: 59-287/293.0
SFVAVDTNRIRLSITNDIPCSEYINASYIDSYNEAHEYIATQAPMENTINEFWQMVWEQKCTAIVMLTELQDRGQIESELYWPRD-GCVRYGKYIVTKID
.. |..|..|. ..| . |.||||.||. || .|.|||| |. .|...||.||||.|...|||||.| ..|.. | |||.| | ||. || .
nilpydhsrvkLaalkdesgsDYinanyipgynsprefiatqGPlpetvddfWrmvwekkssiivmltqlvekgkvkCeeYWPadeepvlyGdikvtlva
EEELDDHTQRSM------DSLLVYHFQYHNWSAHGMPPRMNGLVFLHEQVQK-IQSTEDHGPTVVHCSDGAGRTGVFLALAISIERLEAEDTVDIFQTVR
||||.|.. |.. .. | .... |. ||.| . . |. . ..|.. |..|....|.||||| | ||||.|.|| ....| ||.|||| .|
eeeledwvirelkiekekeerkvrqyhftsWpdhgvPektktlldfvrtvreaiektaskrPivvhCsaGvGRtGtfialdrllqaieeedyvdifgiva
WLRSQRPALVGSIEQYSCCYQAVKSYLSW
||..| || . .|| . .|.| ..|.
elReeRnllvqtekqYifihqcvldllrk
|
|||||||||
0045098 | (Phosphotyrosine protein) phosphatases II | 325-546 | 3e-63 | 209.1 | In-house | 41-275 (278) | alignment | ||
Range on Protein: 325-546
Range on HMM: 41-275/278.0
SFVAVDTNRIRlsitndipcsEYINASYIDSYneAHEYIATQAPMENTINEFWQMVWEQKCTAIVMLTELQDRGQIESELYWPRDGCVRYGKYIVTKIDE
.....| .|.. .||||||||.| ...||||.|...|.. ||.|.||...|.|||||||...|.. . ||| .|...||.. || ..|
dilpydhsrVk..........dYINAsyidgy..pkkfIatqgPlpstvadfwrmlwelgitvivmltelvelgrekcaqywpeggsltygdftvtllse
EELDDHTQ------------RSMDSLLVYHFQYHNWSAHGMPPRM--NGLVFLHEQVQKIQS------------TEDHGPTVVHCSDGAGRTGVFLALAI
|.||| | . |. |.|..|..| || |. . . | |.... .. ...||..|||| | ||||.. |. .
evlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllsslllldsggpvlVHCsaGvgRtGtlvaayl
SIERLeaEDTVDIFQTVRWLRSQRPA-LVGSIEQYSCCYQAVKSYLSWR
.|.| |..||....|..|||||| | . ||| .|... .|...
mlell..eggvdlleavkelrsqRpglavqnleqyrflyefllelllrg
|
|||||||||
subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 325-544 | 9.2e-55 | 180.7 | In-house | 49-277 (281) | alignment | ||
Range on Protein: 325-544
Range on HMM: 49-277/281.0
SFVAVDTNRIRLSITNDIPCSEYINASYIDSYNEAHEYIATQAPMENTINEFWQMVWEQKCTAIVMLTELQDRGQIESELYWPRDG-CVRYGKYIVTKID
|| | |.... ... ..||||.....|.. .||||||.|. .....||||||||| .||||.|. . |.. ||| | ..||...|...
nivaYDatrvkvtpneenkntDYinanfvpgykgekeyiatqgPvPaslvafWqmvweqkvsaivmvtreieagklkChrYWPddnselkygdvtvksta
EEELDDHTQRSMD-------SLLVYHFQYHNWSAHGMPPRMNGLVFLHEQVQKIQSTEDHGPTVVHCSDGAGRTGVFLALAISIERLEAE-DTVDIFQTV
||| . .| . . | ...| .| ||.| . |. ...|.|..... . | |.||| | ||||...|| ....||| ..|. ..|
eeekatyierkfkleresgetreveqlaytaWPdhGvPattkellefrkevlkltekktkaplvihCsaGvGrtGtyialDrlvkaveaeleeldvkavv
RWLRSQRPALVGSIEQYSCCYQAVKSYLS
. || .| .| .. ||. |.||. .|.
aelrkernlmvqtvvqyefvykavldald
|
|||||||||
subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 325-540 | 2e-53 | 176.8 | In-house | 69-288 (319) | alignment | ||
Range on Protein: 325-540
Range on HMM: 69-288/319.0
SFVAVDTNRIRLSITNDIPCSEYINASYIDSYNEAHEYIATQAPMENTINEFWQMVWEQKCTAIVMLTelqdrgQIESELYWPRDGCVRYGKYIVTKIDE
.| | |...| .. . |.|||||... | |||.| |..||...||.|.||..|..||.|| . ||| .. ...... |
nilafdknvvklerliGeefsdyinasfvtGyqrkdkyiaaqGPldntladfWrmiweyncstivllt......kdkcsqywplkivikeerfkvkvdsv
EELDDHTQRSMD---------SLLVYHFQYHNWSAHGMPPRMNGLVFLHEQVQKIQSTEDH-GPTVVHCSDGAGRTGVFLALAISIERLEAEDTVDIFQT
|| .... |... . | . | .|.| |. | ..|....| |.| . ||||| |.|||||...| . ..|.. |. ||....
eetaeyvvrdielsedgkekdirkitqfhflGwpdvGvpdypsdlmrlvkkvrhltskenhranivvhcsaGvGrtGvyivldvlldrmkeekqvdvynf
VRWLRSQRPALVGSIEQYSCCYQAVK
|| || ||. || .. || .| |.
vrdlrqqrntlvqdlvqykfiysall
|
|||||||||
subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 325-544 | 4.2e-52 | 172.1 | In-house | 59-285 (297) | alignment | ||
Range on Protein: 325-544
Range on HMM: 59-285/297.0
SFVAVDTNRIRLSITNDIPCSEYINASYIDSYNEahEYIATQAPMENTINEFWQMVWEQKCTAIVMLTELQDRGQiESELYWPRDGCVRYGKYIVTKIDE
. .|..|..| |.|| | |.|.|||.. .... ..|.|| ||..|...||.||.... ..||||.....| . . ||. .| . .|. |.
niLPydssRvkLaivnddpdsDyvnasfvkgnkh..rlittqmPmkatvadfWamvldeqvstivmlnddnerdk.kcaryWsdkgvttfGdvsvvllsv
EELDDHTQRSMD--------SLLVYHFQYHNWSAHGMPP--RMNGLVFLHEQVQKIQSTEDHGPTVVHCSDGAGRTGVFLALAISIERLEAEDTVDIFQT
.| .|... .| .|. .| . .. ... |. | ..|.| |.. .|| .|||. | |||||.|.. . . . |..||||..
sereGfikrelevtkgkakarrvvkqyqfveWPdkaverkdsassllklisevrkdfsqnaegPllvhclaGvGrtgvlltidsvvaeakrekevdifgl
VRWLRSQRPALVGSIEQYSCCYQAVKSYLS
|. || .|| || |||. |.|| .|.
vkklrqerpylvqtkeqykfvyvavleall
|
|||||||||
subfamily_Sponge-PTP6_pd | Subfamily Sponge-PTP6 | 325-544 | 3.9e-44 | 145.8 | In-house | 56-280 (439) | alignment | ||
Range on Protein: 325-544
Range on HMM: 56-280/439.0
SFVAVDTNRIRLSITNDIPCSEYINASYIDSYNEAHEYIATQAPMENTINEFWQMVWEQKCTAIVMLTELQDRGQieselYWPRDGCVRYGKYIVTKIDE
. .| | |. | . .| | |||| ||. | . . |||||.| ..| ..||..|.|.|.. |||||.| . . ||| |. | || .| .
dvgafdhtrvtlqeipgvphshyinanyikGyyddklyiatqgpkkettddfwrlviekktvtivmltnlvesyk.....ywpsdaevcygdiavrvdrn
EELDDHTQRSMD----------SLLVYHFQYHNWSAHGMPPRMNGLVFLHEQVQKIQSTEDHGPTVVHCSDGAGRTGVFLALAISIERLEAEDTVDIFQT
|| ... | . | .|.| | . .| . .. . .. . .|. || ||||| | |||| .|| |..|.| .|. |||
ielpnyvirgfkvfnerdttekertvlqfhyiawpdknvpaqashvldflrainsandkeeygpvvvhcsagvGrtGtiialdialeqlklenkvdikgi
VRWLRSQRPALVGSIEQYSCCYQAVKSYLS
|. || || .| .. || |.|| .
vkvlrkqrkqmvqalcqyvfiynavlediv
|
|||||||||
0049772 | (Phosphotyrosine protein) phosphatases II | 325-547 | 1.8e-37 | 125.1 | In-house | 54-284 (314) | alignment | ||
Range on Protein: 325-547
Range on HMM: 54-284/314.0
SFVAVDtNRIRLsITNDIPCSEYINASYIDSYneaHEYIATQAPMENTINEF----------WQMV--WEQKCTAIVM---------------------L
.. .| || .| . .. | ||||||.|.. .||||.|.|.|.. | |.|| ..... ||| |
dilpad.nrvil.pglpvsgsdyinasyvdgf...lkfIatqgpleitvvdfreepvlyyngwrmvlrgdlnvrdivmsrdevladelsrLdaAlgKtpl
TELQDRGqieselywpRDGCVRYGKYIVtkideEELDDHTQRsmdSLLVYHFQYHNWSAhGMPPRMNGLVFLHEQVQKIqstEDHGPTVVHCSDGAGRTG
..| .| .... ... |||.|. . |.... ..... | .| . . . | ... ...||..|||..| ||||
lildgng.........neptaadlellk.....eelydpelf...erlgikylripvpD.gsaplledfdeflefieea...dkggpvlvHCkaGkgRtg
VFLALAISIERLeaedTVDIFQTVRWLRSQRP-----ALVGSIEQYSCCYQAVKSYLSWRT
.|...|. . .| |.. ......|..|| .. . ||| ...|.. ||..
tfvvaaylmkll....gvsleealedvrlkRpinpnpgfieqleqyefilealleylkflk
|
|||||||||
subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 325-539 | 5.6e-34 | 112.3 | In-house | 16-237 (239) | alignment | ||
Range on Protein: 325-539
Range on HMM: 16-237/239.0
SFVAVDTNRIRLSITNDIPCSEYINASYIDSYNEA-HEYIATQAPMENTINEFWQMVWEQKCTAIVMLTELQDRGQIESELYWPrDGCVRYGKYIVTKID
|. | .|. | .. | |.||||||. |. . . ||||| .| . .||.|.|... ||||| | . . . ||| | .| . ||
nivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywp.dstskycnlrvtlrk
EEELDDHTQRSM--------DSLLVYHFQYHNWSAHGMPPRMNGLVFLHEQVQKiQSTEDHGPTVVHCSDGAGRTGVFLALAISIERLEAEDTVDIFQTV
| . |. |.. . ||.... | .|.| .. |. .. | .| | |.||| | |||| || . . . . . |||||. |
tevfadyiirtfvmsqvgqteeryvyqyhftvwpdkgvpqyatavlglrrkitk.dslpgarpwvihcsagvgrtgaflvidamlrqakkqktvdifnyv
RWLRSQRPALVGSIEQYSCCYQAV
. .| .|| .| . ||| . ||
kairedrphmvqtseqyvfihlav
|
|||||||||
subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 325-539 | 5.7e-34 | 112.3 | In-house | 15-236 (239) | alignment | ||
Range on Protein: 325-539
Range on HMM: 15-236/239.0
SFVAVDTNRIRLSITNDIPCSEYINASYIDSYNEA-HEYIATQAPMENTINEFWQMVWEQKCTAIVMLTELQDRGQIESELYWPrDGCVRYGKYIVTKID
|. | .|. | .. | |.||||||. |. . . ||||| .| . .||.|.|... ||||| | . . . ||| | .| . ||
nivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywp.dstskycnlrvtlrk
EEELDDHTQRSM--------DSLLVYHFQYHNWSAHGMPPRMNGLVFLHEQVQKiQSTEDHGPTVVHCSDGAGRTGVFLALAISIERLEAEDTVDIFQTV
| . |. |.. . ||.... | .|.| .. |. .. | .| | |.||| | |||| || . . . . . |||||. |
tevfadyiirtfvmsqvgqteeryvyqyhftvwpdkgvpqyatavlglrrkitk.dslpgarpwvihcsagvgrtgaflvidamlrqakkqktvdifnyv
RWLRSQRPALVGSIEQYSCCYQAV
. .| .|| .| . ||| . ||
kairedrphmvqtseqyvfihlav
|
|||||||||
subfamily_Cele-PTP-13_pd | Subfamily Cele-PTP-13 | 325-538 | 2.2e-24 | 80.6 | In-house | 45-264 (281) | alignment | ||
Range on Protein: 325-538
Range on HMM: 45-264/281.0
SFVAVDTNRIRLSI-TNDIPCSEYINASYIDSYNEAHEYIATQAPMENTINEFWQMVWEQKCTAIVMLTELQDRGQIESELYWPRD--GCVRYGKYIVTK
..| |..| . . ..|| | || | . || || | ..| .||.|.|... |||||| .. . . . |.||. |... |. |.
nipcldisrvqlkvkmpnknstdyihanyirspflkrgyiltqgpkketradfwrmiwqenttaivmlcqfletnrekcaeyfprnahcclqfdklsvsy
IDEEELDD----HTQRS--MDSLLVYHFQYHNWSAHGMPPRMNglVFLhEQVQKIQSTedHGPTVVHCSDGAGRTGVFLALAISIERLEAEDTV-DIFQT
| . . | .. |. |. ...| .| . |.| . ..||.. | |.||| | ||.| ..|. |... . . |. || |
edstvnkslvttrlnlsyegetrlithwlwkewpdwqvpesse..vml.kilrkirar..stppvihcsagvgrsgtlmaveialqsihshftlpdikqi
VRWLRS-QRPALVGSIEQYSCCYQA
| || | | | ...|| ..
vshlrvtgraasvqtlqqymliwkv
|
|||||||||
subfamily_Cele-PTP-14_pd | Subfamily Cele-PTP-14 | 325-524 | 7.8e-22 | 72.2 | In-house | 60-271 (310) | alignment | ||
Range on Protein: 325-524
Range on HMM: 60-271/310.0
SFVAVDTNRIRLSITNDiPCSEYINASYIDSYNEAHEYIATQAPMENTINEFWQMVWEQKCTAIVMLTELQDRGQIESELYWPRDGCV-RYGKYIVTKID
| || |..| | . .|| | |. . .| .| |.. || .||.|...... .|..| . |. . ||| | || ||..
dvvcldtsrvklkidks.ryedyihanyvktnylrstficsqgplqhtiidfwrmifqeraesilllckvgeegrpkcvgywpslgvtetygcirvtnls
EE--E---------------LDDHTQRSMDSLLVYHFQYHNWSAHGMPPRMnglvfLHEQVQKIQSTEDHGPTVVHCSDGAGRTGVFLALAISIERLEAE
| | | .. | | .. || |.| | |.. . ||| ||||| | .|..| .|| ..|..|.
esseefeicnlavtfvpdnvpvdeqpanlkelrvslikwpnwpdrgvpdek.....chtvpqrllaqvrhgpcvvhcsagkdrlyvvvalklkidkldrg
DTVDIFQTVRWLRSQRPA
. ||. . . |. .|
lkvdaeevktellksrai
|
|||||||||
subfamily_PTPRD_pd | Subfamily PTPRD | 326-544 | 8.8e-79 | 260.6 | In-house | 57-282 (564) | alignment | ||
Range on Protein: 326-544
Range on HMM: 57-282/564.0
FVAVDTNRIRLSITNDIPCSEYINASYIDSYNEAHEYIATQAPMENTINEFWQMVWEQKCTAIVMLTELQDRGQIESELYWPRDGCVRYGKYIVTKIDEE
|| |..|..|| .. . |.|||||.||.|.. ..|||||.|...||..||.|||||... |||||.|...|. . . ||| .| .||...|| .||
ivaYdhsRVvLskvegdegsDYINAsfidgyrkrkayIAtqgPlaetiedFWRmvweqnsstiVmltkleEkgkvkchkYWPekgtetygeltVtleeee
ELDDHTQR--------SMDSLLVYHFQYHNWSAHGMPPRMNGLVFLHEQVQKIQsTEDHGPTVVHCSDGAGRTGVFLALAISIERLEAEDTVDIFQTVRW
|| | . | |..| | .|.. .| ||.| ..|. | ..|.... ..|.||.||||| | ||||.|... . .||...|.||||.|.|.
eladyeirtfklkkkkssesreVrqFhFtsWPdhgvpesatslLdlirkvraln.epdagPivVhCSaGVGRTGtfividamlerikeektvDiyqyvka
LRSQRPALVGSIEQYSCCYQAVKSYLS
||.||.|.| . |||. ...|. .|.
lrkqRnamVqteeQYiFiheaileala
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 326-539 | 2e-66 | 219.1 | Pfam-A | 10-233 (235) | alignment | ||
Range on Protein: 326-539
Range on HMM: 10-233/235.0
FVAVDTNRIRLsiTNDIPCSEYINASYIDSYNEAHEYIATQAPMENTINEFWQMVWEQKCTAIVMLTELQDRGQIESELYWP--RDGCVRYGKYIVTKI-
... | .|..| ... |.||||.|...|.| ...||||.|...||..||.|||..|...|||||.|...|. . . ||| ... ..||.. |.
ilpydktrvkl..kgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeesltygdikvelke
DEE-ELDDHTQRSM---------DSLLVYHFQYHNWSAHGMPPRMNGLVFLHEQVQKIQsTEDHGPTVVHCSDGAGRTGVFLALAISIERLEAEDTVDIF
.|. . .. | | . .. |....|.|| ||.| ..|. | ..|.| . ....||.|||||.|.||||.|.|| | .|.||||..||..
kekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkveksk.eaksgpvvVhCsaGvgRtgtfvaldilleqleaeeevdvl
QTVRWLRSQRPALVGSIEQYSCCYQAV
|.|. ||.||| .| |.||| .|.|.
qivkelRkqRpgmvqsleqYiflykai
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 326-539 | 2e-66 | 219.1 | In-house | 10-233 (235) | alignment | ||
Range on Protein: 326-539
Range on HMM: 10-233/235.0
FVAVDTNRIRLsiTNDIPCSEYINASYIDSYNEAHEYIATQAPMENTINEFWQMVWEQKCTAIVMLTELQDRGQIESELYWP--RDGCVRYGKYIVTKI-
... | .|..| ... |.||||.|...|.| ...||||.|...||..||.|||..|...|||||.|...|. . . ||| ... ..||.. |.
ilpydktrvkl..kgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeesltygdikvelke
DEE-ELDDHTQRSM---------DSLLVYHFQYHNWSAHGMPPRMNGLVFLHEQVQKIQsTEDHGPTVVHCSDGAGRTGVFLALAISIERLEAEDTVDIF
.|. . .. | | . .. |....|.|| ||.| ..|. | ..|.| . ....||.|||||.|.||||.|.|| | .|.||||..||..
kekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkveksk.eaksgpvvVhCsaGvgRtgtfvaldilleqleaeeevdvl
QTVRWLRSQRPALVGSIEQYSCCYQAV
|.|. ||.||| .| |.||| .|.|.
qivkelRkqRpgmvqsleqYiflykai
|
|||||||||
subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 326-547 | 1e-56 | 187.1 | In-house | 53-281 (315) | alignment | ||
Range on Protein: 326-547
Range on HMM: 53-281/315.0
FVAVDTNRIRLSITNDIPCSEYINASYIDSYNEAHEYIATQAPMENTINEFWQMVWEQKCTAIVMLTELQDRGQIESELYWPR--DGCVRYGKYIVTKID
. .|..|..| . .|.| |.||||||| |... . |||.|.| . ....||.||...| |.|||.|..|. .|. ||| |..|.. |. ..
ilPldsarvkleviddsPdsdyinasyiksvdddkayiasqgPlkasvddfwrmvlqekvttivmvtkkqegdkikcrqywPdrkadsvefGsikvells
EEELDDHTQRSM------DSLLVYHFQYHNWSAHGMPPRMNGLVFLHEQVQKIQSTEDHgPTVVHCSDGAGRTGVFLALAISIERLEAEDTVDIFQTVRW
| | ..| . .| | ||...| .| . .. |. | .|. . .... . .|||| |.|||||.... ..... ...||.|..|.
leadtdgvarklvtrkseesrtvtqfqftewPdkGvdkqtssllklikevkadngkkef.sllvhcsaGvGrtGvvisidevvaqikrtrsvdvfnfvkn
LRSQRPALVGSIEQYSCCYQAVKSYLSWRT
||..|| || . |.|. |.||. .| ||
lrakrpylvqteeeyafiydavledllwrn
|
|||||||||
subfamily_PTPN9_pd | Subfamily PTPN9 | 326-542 | 5.9e-56 | 184.7 | In-house | 51-289 (297) | alignment | ||
Range on Protein: 326-542
Range on HMM: 51-289/297.0
FVAVDTNRIRLSITNDIPCSEYINASYIDSYNEAHEYIATQAPMENTINEFWQMVWEQKCTAIVMLTELQDRGQIESELYWP--RDGCVRYGKYIVTKID
. .| |. |. ... ..|.||||...| |.. . .|||| |...|...||.|||||.. ||| | . .||.. ||| .. . ..|.. |....
vlcydetrvvlakvdedeasdyinanfvdGykqkkafiatqGplkktvsdfWrmvWeqevlvivmttrvvergrlkcgqyWpleeessaefgdlsvsnve
EEELDDHTQRSMD--------SLLVYHFQYHNWSAHGMPPRMNGLVFLHEQVQKIQSTE------------DHGPTVVHCSDGAGRTGVFLALAISIERL
|| .|...|.. | | |||. | .|.| . |. . |.|.. |.. . | ||||| | |||| | .| |...||
veeeedykvrvleiknvkteesrkvthfqflsWPdyGvPssaaslldvlekvrekqalavkelgdewkghpsgPPivvhcsaGiGrtGtfitldiclsrl
EAEDTVDIFQTVRWLRSQRPALVGSIEQYSCCYQAVKSY
| ..|||...||. ||.|| . ||| ||.|| |
eevgtvdvvetvkllrtqrafsiqtpeqyefcylavley
|
|||||||||
subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 326-540 | 6.5e-53 | 175.1 | In-house | 34-252 (284) | alignment | ||
Range on Protein: 326-540
Range on HMM: 34-252/284.0
FVAVDTNRIRLSITNDIPCSEYINASYIDSYNEAHEYIATQAPMENTINEFWQMVWEQKCTAIVMLTelqdrgQIESELYWPRDGCVRYGKYIVTKIDEE
.| | |...| . . |.|||||.| | . ||||| |..||...||.|.||..|..||.|| . ||| .. ...... | |
ilafdknvvklerliGeefsdyinasfitGyqrkdkyiatqGPldntladfWrmiweyncstivllt......kdkcsqywplkivikeerfkvkvdsve
ELDDHTQRSM---------DSLLVYHFQYHNWSAHGMPPRMNGLVFLHEQVQKIQSTEDH-GPTVVHCSDGAGRTGVFLALAISIERLEAEDTVDIFQTV
| .... |.. | . | . | .|.| |. | ..|....| |.| . ||||| |.|||||...| . ..|.. |. ||....|
eseeyvvrdielsedgkekdirkirqfhflgwpdvgvpdypsdlmrlvkkvrhltskenhranivvhcsagvgrtgvyivldvlldrmkeekqvdvynfv
RWLRSQRPALVGSIEQYSCCYQAVK
| || ||. || .. || .| |.
rdlrqqrntlvqdlvqykfiysall
|
|||||||||
subfamily_Sponge-PTP9_pd | Subfamily Sponge-PTP9 | 326-546 | 1.7e-47 | 156.6 | In-house | 49-296 (301) | alignment | ||
Range on Protein: 326-546
Range on HMM: 49-296/301.0
FVAVDTNRIRLSITN--DIPCSEYINASYIDSYNEAHEYIATQAPMENTINEFWQMVWEQKCTAIVMLTELQDRGQIESELYWPRDGCVR--YGKYIVTK
. .| ||| |. .. |. |||||||||.|.|....||.|.||..|. .||...|..| ..|||.|.|... . ..| |||. . .|. ||
itvyddnriilkpkpnldlcqreyinasyidgysekkkfiaaqgpmkktlvdfWrliwqekpvsivmvtnlkegtkskceqywpnseaeseefgpftvtl
IDEEELDDHTQR-----------------------SMDSLLVYHFQYHNWSAHGM-PPRMNGLVFLHEQVQKIQSTeDHGPTVVHCSDGAGRTGVFLALA
..| . |.. | ...| | .| .| .|. . | ....... |. . || ||||||. .|.||. ..
vneqvyPdfvirqlnvkiqdgsnngyierkfkvksdksswdvlqlqvtdWpqdGvvreprtvLqviddvihrqqki.gggpvvVHCSdtVsrsGvYcsvs
ISIERLEAEDTVDIFQTVRWLRSQRPALVGSIEQYSCCYQAVKSYLSWR
|..| || ||.|| .. .| ..| | .|||. |.... ||.
iglEQckaegVVdvfqvtkavrrskpgaVtTLeqytsiydvidmylqln
|
|||||||||
subfamily_Urchin-PTP-4_pd | Subfamily Urchin-PTP-4 | 326-546 | 7.7e-38 | 124.9 | In-house | 54-239 (392) | alignment | ||
Range on Protein: 326-546
Range on HMM: 54-239/392.0
FVAVDTNRIRLSITNDIPCSEYINASYIDSYNEAHEYIATQAPMENTINEFWQMVWEQKCTAIVMLTELQDRGqieselywprdgcvrygkyivtkidee
. |..|..| . .||| |.|.|||||.|.. . |||.|.| ....||.||.... |.|.|.|.|..
ilpydsarvkleviddipdsdylnasyipsfdnekayiasqgpnaaslddfwrmvfqenvttiamvtklkegd...........................
elddhtqRSMDSLLVYHFQYHNWSAHGMPPRMNGLVFLHEQVqKIQSTEDHGPTVVHCSDGAGRTGVFLALAISIERLEAEDTVDIFQTVRWLRSQRPAL
. | | |.. .| ...| . . |. . ..| |.. . | ..||| | ||||| ... . . . ||.|. | .| .|| .
.......kgddartvaqfhftewPdkdvpkhtssllkfikev.kadfGqythpliihcsagvgrtgvvisidsvvahakktrmvdvfnfvtnirrkrpym
VGSIEQYSCCYQAVKSYLSWR
| . |||. | || | ||
vqtkeqyafiygavledllwr
|
|||||||||
subfamily_egg_pd | Subfamily egg | 326-541 | 5.1e-22 | 72.9 | In-house | 49-268 (307) | alignment | ||
Range on Protein: 326-541
Range on HMM: 49-268/307.0
FVAVDTNRIRLSITNDIPCSEYINASYIDSYNEAHEYIATQAPMENTINEFWQMVWEQKCTAIVMLTELQDRgqIESELYWPRD--GCVRY--GKYIVTK
|. |..| . . ..| | ... |.| .|||. || ..||.||..... ||||| .. . | |||. ... | . ..
vhckdssrvklelrrGqylddfihanrvkGkpllnefilaqaplkntvddfwrmvfqeevqyivmltsrkes..erceyywpkaesdslvtvpGslrien
IDEEELDDHTQRSMDSLLVYHFQYHNWSAHGMpPRMNGLVFLHEQVQKIQST-EDHGPTVVHCSDGAGRTGVFLALAISIERLEAEDT--VDIFQTVRWL
.. .. | | || . . | .| . .. .. .. . |.||.. .| ......|. |.. | . . ..| .|
lkvdskadplfrvtklklvGgddeerflehwq.gdvnnssdvysplrvlrklrnlskpvvvqdilGvskaatlvaieiallsllrGpitkslvlravvfl
RSQRPALVGSIEQYSCCYQAVKS
| .|. | |. .| |. |
rlrrrlsvesvllylfvyrlvlf
|
|||||||||
subfamily_PTPN12_pd | Subfamily PTPN12 | 327-544 | 5e-52 | 171.6 | In-house | 50-278 (290) | alignment | ||
Range on Protein: 327-544
Range on HMM: 50-278/290.0
VAVDTNRIRLSITNDIPCSEYINASYIDSYNEAHEYIATQAPMENTINEFWQMVWEQKCTAIVMLTELQDRGQIESELYWPRDG--CVRYGKYIVTKIDE
. |..|. || ... . |.||||..| .. .||||.|.|. .|...||.|.||.. . .||. .. . |.. | ||| | ...|.. ||...|
lPydksrvelskieeeegsdYinanfikgvegkleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkkCerYWpeegeeelefgefevtleee
EELD-DHTQRS------MDSLLVYHFQYHNWSAHGMPPRMNGLVFLHEQVQKIQStEDHGPTVVHCSDGAGRTGVFLALAISIERLEAEDT---VDIFQT
. .| |.. |. .| || |.|..| ||.| ... |. | |.|...|. ... | ||||| | ||||. .|. . | |.|| . .|.|.
kavdddflirtLkveaqkesrkvyqfhYtaWPDhgvPssaksllelielvrelqe.sedaPlvvhCsaGvGrtGtiiaidyvrellkaekipeeldvfdl
VRWLRSQRPALVGSIEQYSCCYQAVKSYLS
|. || ||.||| . |||. |.|| ....
vlelrkqraalvqtkeqyelvykavaelvq
|
|||||||||
subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 327-539 | 2e-40 | 133.5 | In-house | 13-235 (237) | alignment | ||
Range on Protein: 327-539
Range on HMM: 13-235/237.0
VAVDTNRIRLSITNDIpcSEYINASYIDSYNEA-HEYIATQAPMENTINEFWQMVWEQKCTAIVMLTELQDRGQIESELYWPR-DGCVRYGKYIVTKIDE
|| | .|. | . |.||||.|..... . ..|||.| |.|.. ..||||||..||. ||||| | .. .. ||| | ||.. |. .
vaydhsrvvlkgagsg..sdyinatylkgfdgtpkkyiaaqgplesscddfwqmvwqekcsvivmltgliegnelkchkywpstdqpaaygvltvslkkk
EELDDHTQRSMD---------SLLVYHFQYHNWSAHGMPPRMNGLV-FLHEQVQKIQSTEDHGPTVVHCSDGAGRTGVFLALAISIERLEAEDTVDIFQT
||. |.| ||. |.. .|. | .|.| . |. | .. ... . . || ..||| | ||||.|| . . . . . |||..
eefsdytvrslllskrltlkevrlihqyqftswpdrgvpqqtaallrfrkniinrsphvsesgpwiihcsagvgrtgiflvidamlrqakekkvvdiyny
VRWLRSQRPALVGSIEQYSCCYQAV
| . .|| .. . .|| .|..
vysieedrpyiiqtkdqyvfihqti
|
|||||||||
subfamily_Cele-PTP-16_pd | Subfamily Cele-PTP-16 | 327-539 | 3.3e-12 | 40.6 | In-house | 57-275 (303) | alignment | ||
Range on Protein: 327-539
Range on HMM: 57-275/303.0
VAVDTNRIRLSitnDipcSEYINASYIDsYNEAHEYIATQAPMENTINEFWQMVWEQKCTAIVMLTELQDRGQIESELYWPRD--------GCVRYGKYI
. .| ...|| | | || |||.. . . | || |. | .||||. ||| ...| . .. . .||. .| |..
icldhskvkls...d...ssyihasyle.ldsskkailtqlplshtaadfwqmiieqkvkcvlllltdseydklggdsvfprnqdflkfeersirvgefk
VTKIDEE-ELDDH--TQRSMDSLLVYHfQYHNWSAHGMPPrmNGLVFLHEQVQKIQS----TEDHGPTVVHCSDGAGRTGVFLALAISIERLEAE-DTVD
.. . | .. . |.| | .|..| .| .| . |. ..|| | ||| | ||.| | . . | .| ..|
rvelgdgwvlkvlsvsngdyksflhvh.hykawphnsips..dgspkfvkqiwqlqsvlrkysdstptvymslsgcgragtfalfetahlslhseqasld
IFQTVRWLRSQRPALVGSIEQYSCCYQAV
. . . .| | | . |.| | .
lvkclenvrngrlhavqnlsqfsvvytll
|
|||||||||
subfamily_Sponge-PTP4_pd | Subfamily Sponge-PTP4 | 327-414 | 5e-11 | 36.7 | In-house | 106-186 (244) | alignment | ||
Range on Protein: 327-414
Range on HMM: 106-186/244.0
VAVDTNRIRLSITNdiPCSEYINASYIDSYNEAHEYIATQAPMENTINEFWQMVWEQKCTAIVMLTELQdrgqiESELYWPRDGCVRY
. .| ||. || . |||||.. . ||| || |. .| .||.|. |.. .|.| .. | . ||| . .
lpfdfnrvplskgs..mgntyinasfvgclgrtaeyiltqhpladtsmdfwkmmlerhvnvlvvlgsve.....eedeywpdseplew
|
|||||||||
subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 328-547 | 1.5e-54 | 180.0 | In-house | 54-280 (515) | alignment | ||
Range on Protein: 328-547
Range on HMM: 54-280/515.0
AVDTNRIRLSITNDIPCSEYINASYIDSYNEAHEYIATQAPMENTINEFWQMVWEQKCTAIVMLTELQDRGQIESELYWPR--DGCVRYGKYIVTKIDEE
|..|..| . || | |.|.||||| |.. . |||.|.| . ....||..|.... |.|.|.|.|.. .| ||| |..|.. | . |
PydsvrvklevindnPhsdyfnasyipsfdndkayiasqgPnkasvddfWrlvlqenvttiamvtklkegdkikcgkyWPdkpgdsvkfGsikvelvsle
ELDDHTQRSM------DSLLVYHFQYHNWSAHGMPPRMNGLVFLHEQVQKIQSTEDHgPTVVHCSDGAGRTGVFLALAISIERLEAEDTVDIFQTVRWLR
. ..| . || | |....| .|.|.. . |. | .|. .. | | ..||| |.|||||.... . . . ..||.|..|. .|
actggikrkltvlkgddsrtvtqfhfteWPdkGvpkhtssllklikevkadhgqyth.pliihcsaGvGrtGvvisidsvvahakttrmvdvfnfvtnir
SQRPALVGSIEQYSCCYQAVKSYLSWRT
.|| || |||. |.||. .| ||
qkrpylvqtqeqyafiygavledllwrn
|
|||||||||
subfamily_PTPN3_pd | Subfamily PTPN3 | 328-539 | 3.5e-46 | 152.4 | In-house | 52-272 (280) | alignment | ||
Range on Protein: 328-539
Range on HMM: 52-272/280.0
AVDTNRIRLSITNDipcsEYINASYID----SYNEAHEYIATQAPMENTINEFWQMVWEQKCTAIVMLTELQDRGQIESELYWPRD-GCVRYGKYIVTKI
. |. |..|. .. .||||.|.. | . ||||| |...| ..|||||||||.. |||||.| .||.. |||. ..||.. |.
pydatrvklkeset....dyinanyvnmeipstglvnryiatqGPlaktatdfWqmvweqksslivmlttlverGrvkChqyWPetedeleygefsvkce
DEEELDDHTQRSM--------DSLLVYHFQYHNWSAHGMPPRMNGLVFLHEQVQKIQSTEDHgPTVVHCSDGAGRTGVFLALAISIERLEAEDTVDIFQT
|.| . | . .. . ..|| .|. ||.| . .. . |.|.|..|.... |.||||| | |||||...| ... .||.. | . .
kedetksyvlrelvlkdketkeerkilqlqylaWpdhgvPddsadflefvervrklrsgkee.PvvvhCsaGigrtGvlilletalalieaaepvypldi
VRWLRSQRPALVGSIEQYSCCYQA-V
|| .| || .|| . .|| .| .
vrtmrdqramlvqtasqykfvCeail
|
|||||||||
subfamily_PTPN13_pd | Subfamily PTPN13 | 328-542 | 2.6e-44 | 146.5 | In-house | 48-268 (273) | alignment | ||
Range on Protein: 328-542
Range on HMM: 48-268/273.0
AVDTNRIRLSITNDipcseYINASYIDS--YNEAHEYIATQAPMENTINEFWQMVWEQKCTAIVMLTELQDRGQIESELYWPRD---GCVRYGKYIVTKI
.| |..|. |||||.| .. .||||.| |. .|...|||||||||.. |.|.| ...|.. . ||| . .... |...
Pydetrvklgdegg.....yinaslikvpvgkdeyeyiacqGPlPetvkdfwqmvweqkaeviamvtlekekgkvkchrywPesknkklkvsnrlevell
DEEELDDHTQRSM--------DSLLVYHFQYHNWSAHGMPPRMNGLVFLHEQVQKIQSteDHGPTVVHCSDGAGRTGVFLALAISIERLEAEDTVDIFQT
. ..||. ..|.. .| | |... .| ||.| . |. . .|...|. |.|| ||||| | ||.|..... . .. .| . .|. ..
kvqkldgfvvralavkdsesgesrevahlnfvkwPdhgvPssaaellqfvaevrrlqt..dagPivvhcsaGiGrsGtlitidvvlglierdkefdvkei
VRWLRSQRPALVGSIEQYSCCYQAVKSY
|| || || ..| . .|| .|.|.
vrklreqrqgvvqtkdqyifvykailev
|
|||||||||
subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 328-544 | 1.9e-38 | 127.0 | In-house | 44-260 (267) | alignment | ||
Range on Protein: 328-544
Range on HMM: 44-260/267.0
AVDTNRIRLSITNDIpcseYINASYIDSYNEAHEYIATQAPMENTINEFWQMVWEQKCTAIVMLTELQdRGQIesELYWPRD--GCVRYGKYIVTKIDEE
| .|. |. ... ||||||...|. . .|.|| |..||| .|.... .||.. ||.|| ..| |.|| . .| | . |.
pyddtrvilrtkeee....yinasyvegyktknafivtqdplkntitdfltvihdqkvpvivlltkvf.tdni..rlfwPPkmgqakkyqdltvehslek
ELDDHT---------QRSMDSLLVYHFQYHNWSAHGMPpRmngLVFLHEQVQKIQSTEDHGPTVVHCSDGAGRTGVFLALAISIERLEAEDTVDIFQTVR
| .|. . | . .|... .| . | | | . | | . | ||.|||| ||.| || . .||. |...|||. .|
eendyqiitlelkfknesahnvtlyyykkwnintnnkp.y...lkplfgilaknqlengnrPlvvacsdGvGrsGtflvidsqleraktegvsdifdflr
WLRSQRPALVGSIEQYSCCYQAVKSYLS
.||||..|| . |.| ... . |
kirsqriglvdtkeryiyihellaeyae
|
|||||||||
subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 328-538 | 1.8e-26 | 87.5 | In-house | 64-278 (290) | alignment | ||
Range on Protein: 328-538
Range on HMM: 64-278/290.0
AVDTNRIRLSITNDIPCSEYINASYIDSYNEahEYIATQAPMENTINEFWQMVWEQKCTAIVMLTELQDRGQIESELYWPRD-G-CVRYGKYIVTKIDEE
| | . | .| .|. | |.. . .| || ....|. ..|.|| ..| .||||| || . |. | |.| | . .|.. |. |.
dvvcndktrvilkdGydGdyvhanyvkGlka..mfiltqGalkdtvidiwrmvlqekvaaivmlceliedGkakceqyypekeGevltfGeitvlcseed
ELDDHTQRSMDS---------LLVYHFQYHNWSAHGMPPRMNGLVFLHEQVQKIqstedHGPTVVHCSDGAGRTGVFLALAISIERLEAEDTVDIFQTVR
. |..... . | ..|.. | . .. |. . ..|. || ||||| | |||| | |. .... | .|. ..||
dkdaniikktlsvrdkdsGkehklkhlkikswpdksvalstlallrtlrilrka.....sGpvvvhcsaGiGrtGtfvaievglqilldGkeldlldlvr
WLRSQRPALVGSIEQYSCCYQA
|| | . | || ..
alrnsrlnsvqvdiqylalvei
|
|||||||||
subfamily_Cele-PTP-18_pd | Subfamily Cele-PTP-18 | 328-407 | 5.9e-13 | 43.2 | In-house | 59-135 (305) | alignment | ||
Range on Protein: 328-407
Range on HMM: 59-135/305.0
AVDTNRIRLsiTNDIPcSEYINASYIDSYNEAHEYIATQAPMENTINEFWQMVWEQKCTAIVMLTELQDRGQIESELYWP
.| ||..| . | ||| | |. . ... .| ||||.|.| .|| | ...| || || .|...| |..
cldnnrvkl..egpwp.heyihanyvstptnpkrfictqaplektcadfwymclqdkveaifmlcnllekgakkcleyfa
|
|||||||||
0041856 | (Phosphotyrosine protein) phosphatases II | 329-543 | 6e-40 | 132.1 | In-house | 13-171 (182) | alignment | ||
Range on Protein: 329-543
Range on HMM: 13-171/182.0
VDTNRirlsitndipCSEYINASYIDSYNEAHEYIATQAPMENTINEFWQMVWEQKCTAIVMLTelqdrgqieSELYWPrdgcvrygkyivtkideeeld
.| .| . ||||...... | ..||||.|. .|...|..|..|...|.||.|| .|||||
ydhsr..........dldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlt.........eelywp.....................
dhtqrSMDSLLVYHFQYHNWSAHGMPPrMNGLVFLHEQVQKiqsteDHGPTVVHCSDGAGRTGVFLALAISIERleaedTVDIFQTVRWLRSQRPALVGS
. |.....|..| || |. .. |. . |.|.. ..||..|||| | ||||.. |. . ... |.....|...||.|| | .
.....ellerlgiqylylpwpDhgvpd.ldelldfieevle.....eggpvlVHCsaGvgRtgtlvaaylmkkl.....gvsleeavklvrsrRpgmvit
IEQYSCCYQAVKSYL
.|| ...|. .|
pnqyfflqlallell
|
|||||||||
subfamily_PTPN1_pd | Subfamily PTPN1 | 329-539 | 1.5e-39 | 130.5 | In-house | 44-267 (290) | alignment | ||
Range on Protein: 329-539
Range on HMM: 44-267/290.0
VDTNRIRLSITNDipcsEYINASYIDSYNEAHEYIATQAPMENTINEFWQMVWEQKCTAIVMLTELQDRGQIESELYWPRD---GCVRYG--KYIVTKID
| ||.| .. .||||| .. . ..|| || |. ||.. |||||||||. |.||| .. ...|| |||.. .. . |. |. |
ydhsrikleradn....dyinaslveleeakrsyiltqGPlpntvdhfWqmvWeqkskavvmlnkvvekeqikcaqywPqgeeekellledtklkvklis
EEELDDHTQRSM--------DSLLVYHFQYHNWSAHGMPPRMNG-LVFLHEQVQKIQSTEDHGPTVVHCSDGAGRTGVFLALAISIERLE---AEDTVDI
||. . .| | . .. ..|| | |. |.| . | ||.. . ..|.||.|.||| | ||.| | . . ..| ..|||
eerksyytvrllelenlktqetreilhfhyttwpdfgvpespaaflkflfkvresGslssdvGpavihcsaGiGrsGtfclvdtclvliekkddlssvdi
FQTVRWLRSQRPALVGSIEQYSCCYQAV
... ||..| |. .| |.|.
kkvllelrkyrlGliqtadqlrfsylai
|
|||||||||
0044763 | (Phosphotyrosine protein) phosphatases II | 329-546 | 2.2e-31 | 104.2 | In-house | 2-174 (178) | alignment | ||
Range on Protein: 329-546
Range on HMM: 2-174/178.0
VDTNRIRLSITNDIPCSEYINASYIDSYneaheYIATQAPMentiNEFWQMVWEQKCTAIVMLTELQDRGQIESELYWPRDGCvrygkyivtkideeeld
.| .| || ....|.|||||.|. . ......|. .......|...|.||.||| . .|.... |||..
ldrtrvllsnleglersdyinaseilpg.....lylgslpp....addlellkelgithivnlteelelgflkcdpywpeeag.................
dhtqrsmdsllvYHFQYHNWSAHGMPPRMNGLVFLHEQVQKIQStEDHGPTVVHCSDGAGRTGVFLALAISIERleaedTVDIFQTVRWLRSQRPaLVGS
..... ... || |. . . ..| ...... |..||..|||| | ||.|.. |. . ... ..... ....|..|| | .
............iqylhipipDhgvpdllehflefvefieeald.ekggpvlVHCsaGvgRsgtlvaaylmkkl.....glsleeaielvrerRp.ivpn
IEQYSCCYQAVKSYLSWR
.|. .|. . .|...
pgqlrqLyefelrllkes
|
|||||||||
subfamily_Cele-PTP-5_pd | Subfamily Cele-PTP-5 | 329-546 | 4.5e-10 | 32.7 | In-house | 75-312 (346) | alignment | ||
Range on Protein: 329-546
Range on HMM: 75-312/346.0
VDTNRIRLSIT---------NDIPCSEYINASYIDSYNEAHEYIATQAP-MEN--TINEFWQMVWEQKCTAIVMLTELQDRGQIESELYWPRDGCVRY-G
| | | |. .|. .. |. .. |. | .| | ||| ...|| |..... . .. . . . |. .| .| |
edvnyinasvitlkdvsrrmacvpayvhlvvlyfvifqfehklivaqlpqmenesfvedfwymiyqeqihlvylmvpddklkntttslfndenggyqytg
KYIVTKID--------EEELDDHTQRSMDSLLVYHFQYHNWSAHGMPPRMNGLVFLHEQVQKIQSTEDHGPTVVHCsDGAGRTGVFLALAISIERLEAED
| .. . | .. . ||... .. | ||. .. . | . .. | || |.||. |. .|..|.
kmfinnrradvsgdpkeytievlpegnsdsvicqvhhhapwkhlqqppktlpiikmihqflsekqvqnagvcvvsl.fgcgracsfigalyainqlnngi
TVDIFQTVRWLRSQRPALVGSIEQYSCCYQAVKSYLSWR
.|.. .. .. ||| | |. ||. | | |.. .
epniceimknikqqrpggvesfaqyasiyaivfdyiark
|
|||||||||
subfamily_Cele-PTP-10_pd | Subfamily Cele-PTP-10 | 330-542 | 4.8e-20 | 66.4 | In-house | 68-288 (305) | alignment | ||
Range on Protein: 330-542
Range on HMM: 68-288/305.0
DTNRIRLsitNDIPCSEYINASYIDSY-NEAHEYIATQAPMENTINEFWQMVWEQKCTAIVMLTELQDRGQIESELYWPRDGC----VRYGkYIVTKID-
| . ..| .. . |.|| | |. . .|..| |...||.||| || ..| |||| . |.. ||| .. | .| ..
dqsavkl...dkpspsdyihanyvgcpmipekrficaqgpldqtidefwwmviqnkveqivmlcktvelgklkcaqywpaaqgeklelksg.ivvenvsg
--EEELDDHTQRSM--------DSLLVYHFQYHNWSAHGMPPRMNGLVflhEQVQKIQSTedHGPTVVHCSDGAGRTGVFLALAISIERL-EAEDTVDIF
| | | .. ... | |.|. .| |.|| . | . |. . . | ||||| | |||| .|. .|.. | . .
skpmerdaeiqitllnltysgdqkmsvrhlqwtewpdrgvppckltsl...ellsairgs..kvpivvhcsagigrtgtivaieyilekiaenkpcppmp
QTVRWLRSQRPALVGSIEQYSCCYQAVKSY
. |. || || . . || .. . |
elvkalrdqrafsiqndvqylfihrvmlny
|
|||||||||
subfamily_Cele-PTP-12_pd | Subfamily Cele-PTP-12 | 330-397 | 1.3e-07 | 25.4 | In-house | 47-113 (332) | alignment | ||
Range on Protein: 330-397
Range on HMM: 47-113/332.0
DTNRIRLSITNdiPCSEYINASYIDSYNEAHEYIATQAPMEN-TINEFWQMVWEQKCTAIVMLTELQDR
| .|. |. . .. |||..| |.. || .|||... | ||.|| |.| . |... .....
dhsrvelapqd..gkddfynaswvdgyskksayifaqapfndhteyvfwrmvserkpsmilvfgdidek
|
|||||||||
subfamily_Cele-PTP-6_pd | Subfamily Cele-PTP-6 | 331-546 | 1.4e-25 | 85.0 | In-house | 53-280 (307) | alignment | ||
Range on Protein: 331-546
Range on HMM: 53-280/307.0
TNRIRLSITNDIPCSEYINASYIDSYNEAHEYIATQAPMENTINEFWQMVWEQKCTAIVMLTELQDRGQIESELYWPRDGC--VRYGK---YI-VTKIDE
.. |. .. | .|.|| | |. . . .|..| |.|||. .|| |. ..| ...|| .. . ..| | ||| . .|. | |...
qdkgrivvkfdglasdyihanylgiaikpkkficaqgplentqysfwamaiqekvesvimlckvielakikceqywpleegqklvfgeapntisvanlga
EE------LDDHT----QRSMDSLLVYHFQYHNWSAHGMPPRMNGLVFLHEQVQkiqstEDHGPTVVHCSDGAGRTGVFLALAISIER-LEAEDTVDIFQ
.. | . | . . .| . |.|..|| .|.|. . . | | |. |. | ||||| | ||.| .|... .. .. .. |. .
kklapdedlinvttlkvdwaqksrtiqhlqwenwpdrgvpqinltainlleavr.....ydtnpvvvhcsaGvGrsGtivaislvqdkmiaGinckdmkk
TVRWLRSQRPALVGSIEQYSCCYQAVKSYLSWR
|. |||||. . . || .. . .|. .
lveelrsqrhyaiqteaqylylhrvlleyflel
|
|||||||||
subfamily_PTPN5_RR_pd | Subfamily PTPN5_RR | 332-544 | 2e-50 | 166.4 | In-house | 43-269 (274) | alignment | ||
Range on Protein: 332-544
Range on HMM: 43-269/274.0
NRIRLS-ITNDIPCSEYINASYIDSYNEA-HEYIATQAPMENTINEFWQMVWEQKCTAIVMLTELQDRGQIESELYWPRDGCV----RYGKYIVTKIDEE
|. |. ... . |.|||| || |.| . |.||| |. ||...||.|....... |||||.|... . . |.| . . |||. .. .
srvllesessededssyinanyikGydeeskayvatqGPlpntvadfWrmiyqeevqvivmltklkeaneqkCavyfPdaedyeiserygdveikvekiv
ELDDHTQRSM------DSLLVYHFQYHNWSAHGMPPRMNGLVFLHEQVQKIQSTEDH--GPTVVHCSDGAGRTGVFLALAISIERLEAEDTVDIFQTVRW
| .|.. |.. .. |.|. | .| | | ..| |. | ..|.. ...|.. .|.||||| | ||||.|.| |.. .|..| .||....|
erndysvrklvlkylerersvkhywytdWPdhksPddantlldlvleveesreeenaklapvvvhCsaGiGrtGcfiaisiavrqlreeivvdvlkivcn
LRSQRPALVGSIEQYSCCYQAVKSYLS
|| .| .| . ||| ..|. ||.
lrldrGGmvqtseqyelihralclylk
|
|||||||||
subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 332-546 | 2.3e-48 | 159.5 | In-house | 35-267 (270) | alignment | ||
Range on Protein: 332-546
Range on HMM: 35-267/270.0
NRIRLSITNDIPCSEYINASYIDSY-NEAHEYIATQAPMENTINEFWQMVWEQKCTAIVMLTELQDRGQIESELYWPRDG----CVRYGKYIVTKIDEEE
|.||. .. . ..|||| |. . .| ..|||...|...|...||.|.||.| |||||.|.|...|. . | ||| . ...|| |... ||
tRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpaepkekvkledgkikvlalseek
LDDHTQRSMD------SLLVYHFQYHNWSAHGMPPRMN------GLVFLHEQVQKIQSTEDHG-PTVVHCSDGAGRTGVFLALAISIERLEAEDTVDIFQ
. . .. . . . ||.|..| ||.|.. . |. . ..|.. .. |.. |..||||.| ||||...|| | .. || . ||. .
eegyiltrlrleekgeerrlvHfwyntWpdhgvpreedsslstdqllkmlravrrsekeldkaePllvHcsaGvgRtGtlialDiavrlLeetkkvdvla
TVRWLRSQRPALVGSIEQYSCCYQAVKSYLSWR
.. || .|.||| ||| |.|| | . |
iieelRkdRmalvqhpeqyeflykavveyaerr
|
|||||||||
0046846 | (Phosphotyrosine protein) phosphatases II | 338-543 | 4.3e-36 | 119.7 | In-house | 5-173 (176) | alignment | ||
Range on Protein: 338-543
Range on HMM: 5-173/176.0
ITNDIPCSEYINASYIDSYneahEYIATQAPMENTINEFWQMVWEQKCTAIVMLTELQDRGQIESELYWPRdgCVRYGKyivtkideeelddhtqrsmds
.. . ... ||||..|... .||||.|...|. .|..|..|...||.|.|||... |.. |||. . ..|
llgldldldyinanlilgs....rpiatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpe..leklgi.....................
llvyHFQYHNWSAHGMPPRmNGLVFLHEQVQKIQSTEdhGPTVVHCSDGAGRTGVFLALAisieRLEAEDTVDIFQTVRWLRSQRP-ALVGSIEQYSCCY
......| || |. . | | |.... .. ||..|||| | ||||...|. || | ..........|.||| | . ||| .|
....qylhlpwpDhgvpdl.elllellefirealkeg..gpvlVHCsaGigRtgtlvaay....llelekglsveealalvreqRplgavqtpeQyrfly
QAVKSYL
.... .|
efellll
|
|||||||||
subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 340-410 | 5.4e-15 | 49.9 | In-house | 83-154 (350) | alignment | ||
Range on Protein: 340-410
Range on HMM: 83-154/350.0
NDipcseYINASYIDSY------NEAHEYIATQAPMENTINEFWQMVWEQKCTAIVMLTELQDRGQIESELYWPRDG
|| ||||.|. | . |||||||. .|...|.... . | . |..||.... . . ||.. .
nD.....YinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvelnlekcyrYWqegs
|
|||||||||
subfamily_Sponge-PTP-4_pd | Subfamily Sponge-PTP-4 | 340-429 | 4.2e-10 | 34.0 | In-house | 8-94 (130) | alignment | ||
Range on Protein: 340-429
Range on HMM: 8-94/130.0
NDIPCSEYINASYIDSYNEAHEYIATQAPMENTINEFWQMVWEQKCTAIVMLTELQdrgqiESELYWPRDGCVR-YG-KYIVTKIDEEELDD
. .. .|||||.. . . ||. ||.|. .| .||.|. |. .|.| .. | . ||| . | . ||| | .| .
srlqgntyinasfvGllgrtaeylltqhpladtsmdfwkmmleryvnvlvvlgsve.....eedeywpdsePlewyeediivtltdrdefkn
|
|||||||||
0051429 | (Phosphotyrosine protein) phosphatases II | 342-549 | 7e-44 | 145.8 | In-house | 1-231 (272) | alignment | ||
Range on Protein: 342-549
Range on HMM: 1-231/272.0
IPCSEYINASYIDSYNE---AHEYIATQAPMENTINEFWQMvWEQKCTAIVMLTELQDRGQIESELYWP------------RDGCVRYGKYIVTKIDEEE
.| | ||||.... |. . ......|...|...||.. .|.....||.|... ||. ..||| . ..||.. || . ||
lplsgyiNardvggygrvvkpgrlyrsggplpltaadfwrl.kelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseel
LDDHTQ---------RSMDSLLVYHFQYHNWSAHGMPPRMngLVFLHEQVQKiqstedHGPTVVHCSDGAGRTGVFLALAISIERLEAEDTVD-------
|.|.. ... |.|..|..| || |. |. | |.... .|| .|||| | .|||.. || ........|. ||
lldyilrellltlllsagearevmhlhytdwpdhgvpqea..llellellld......ggpvlvHCsaGkdRTGtvvallllllgvsletivddYlltnl
-IFQTVRWLRSQRPALVGSIEQYSCCYQAVKSYLSWRTRA
....|..||.|||. | . ||| ..|.|.. .| . .
yleeaveelraqrpgavqteeqylflyeallellrsllsv
|
|||||||||
0043147 | (Phosphotyrosine protein) phosphatases II | 344-542 | 7.3e-39 | 128.6 | In-house | 4-160 (172) | alignment | ||
Range on Protein: 344-542
Range on HMM: 4-160/172.0
CSEYINASYIDSYNEAHEYIATQAPMENTINEFWQMVWEQKCTAIVMLTELqdrgqieselywprdgcvrygkyivtkideeelddHTQRSMDSLLVYHF
| ||||||.| | ...||||.|. ||...||.|..|...|.||.|||| . .. . |....
gsdyinasyldlyyipdrfiatqgplrntladfwrmlkelgithivnltel...................................lydpellerlgiqy
QYHNWSAHGMPpRMNGLVFLHEQVQKIQSTEDHGPTVVHCSDGAGRTGVFLALAISIerleaeDTVDIFQTVRWLRSQRPALVGSIEQYSCCYQAVKSY
.|..| || | .. | . |...... ...||..|||| | ||||.. |. . . ......|...|..|| | . .|| ..|. | .
lylpwpDhgvp.llellleflefidellalspggpvlVHCsaGvgRtgtlvaaylml......lglsleeavalvrekRpgavqnpsqyrflyyfekll
|
|||||||||
0051082 | (Phosphotyrosine protein) phosphatases II | 344-538 | 1.4e-31 | 104.5 | In-house | 2-148 (151) | alignment | ||
Range on Protein: 344-538
Range on HMM: 2-148/151.0
CSEYINASYIDSYneaheYIATQAPMEntinEFWQMVWEQKCTAIVMLTELQDRGqiESELYWPRDGcvrygkyivtkideeelddhtqrsmdsLLVYHF
| |||.||.... ......|.. .|.....|.....||.|.... || |.|. | . |.|.
lsdyinfsyvtgg.....lyrsggpla....dflellkelgiktivnlrseeerg..ycpeylpelg...........................ievlhi
QYHNWSAHGMPPRMNGLVFLHEQVQKiqstEDHGPTVVHCSDGAGRTGVFLALAISIERleaedtVDIFQTVRWLRSQRPALVGSIEQYSCCYQA
....|...|.| . .. ..|.... ..||..|||| | ||||.. || . ... |.........|..|| .| . .|. ....|
pildwpdpglplsfdavleflellld....kkngpvlvHCsaGkgRTGtlvalylmllg......vsleealeeyrlkrpgvvqpnqqflfqlfa
|
|||||||||
subfamily_Cele-PTP-1_pd | Subfamily Cele-PTP-1 | 344-534 | 7.4e-16 | 53.1 | In-house | 45-250 (290) | alignment | ||
Range on Protein: 344-534
Range on HMM: 45-250/290.0
CSEYINASYIdSYNEAHEYIATQAPMEN-------TINEFWQMVWEQKCTAIVMLTELQDRGQIESE----LYWPR--DGCVRYGKYIVTKIDEEELDDH
..|| |... .. . . |.||.| |. ||..|| |. . | . .||| | ... . |. | | .. .... | . |. ||
nddyiHAnrv.tcpnglrliltqsPqekitekrnStiekfwwmakqEkvkqvVmlcefeeksantslfaCakYvpesvgeelkfkgltvkCkskekeddv
TQRSM-------DSLLVYHFQYHNWSAHGMPPRMNGLVFLHEQVQkiqstEDHGPTVVHCSDGAGRTGVFLALAISIERLE-AEDTVDIFQTVRWLRSQR
.| . . | | ....|. ... |. | ..|. . | .||| || | .. |. .. . .. | . . . ||.||
etRelvvkfddeeeftvtHsllkgWnklnvqedtktllsliqkvk.....asktpvivHcvdGiSrsAalaaiilgyQkiaetsgsvkledvlkalrkqr
PALVGSIEQYSC
.. | ....
alaitsalelaf
|
|||||||||
subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 344-407 | 2.6e-09 | 30.8 | In-house | 89-154 (349) | alignment | ||
Range on Protein: 344-407
Range on HMM: 89-154/349.0
CSEYINASYID--SYNEAHEYIATQAPMENTINEFWQMVWEQKCTAIVMLTELQDRGQIESELYWP
.|||| |. .. . |||||||. |...|.... .. .. |.. .. . . ||
lddyinanylkltrisvekkyiatqaPlPstvddfykvillngvklvlsLnddkelslekcdiywq
|
|||||||||
0036282 | (Phosphotyrosine protein) phosphatases II | 345-537 | 2.9e-40 | 133.2 | In-house | 2-164 (174) | alignment | ||
Range on Protein: 345-537
Range on HMM: 2-164/174.0
SEYINASYIDSYNEAHEYIATQAPMEntineFWQMVWEQKCTAIVMLTELQDRGQIESELYWPRdgcvrygkyivtkideeelddhtQRSMDSLLVYHFQ
| |||||..| . ..||.|.|.. ||.|..|...|..|||.|.. .| |||. |. . |.....
sdyinaspldlsyitprliagqgpla.....fwemlkelgittvvmlleekelglykcinywpe.......................lredlerlgiqyl
YHNWSAHGMPPRMNgLVFLHEQVQKIQSTEDHGPTVVHCSDGAGRTGVFLALAISIERLEaEDTVDIFQTVRWLRSQRPALVGSIEQYSCCYQ
| .| ||.|. | . ..|....| ..||..|||| | ||||.. |. . . .|. |..||....|| ||.||| | . .|| .|.
ylpwpDhgvpdlsi.llefvkfveealsedpggpvlVHCsaGvgRtGtlvaaylmlrgll.eslvdaldlvrelRlqrpgmvqtpsQyrflyy
|
|||||||||
subfamily_Cele-PTP-15_pd | Subfamily Cele-PTP-15 | 345-542 | 1.3e-20 | 68.6 | In-house | 59-269 (285) | alignment | ||
Range on Protein: 345-542
Range on HMM: 59-269/285.0
SEYINASYIDSY-NEAHEYIATQAPMENTINEFWQMVWEQKCTAIVMLTELQDRGQIESELYWPRD--GCVRYGKYIVT--KIDEEELDDH---------
.|| ||.. .. ||.|| |. .|...||.|....| . ..|| | . | . ||.| |..||| .| . || .
rdyihaswmrmpgkdqstyittqgplpetlsdfwhmiyqekiayvlmlctlfeggvekcalyypeklgevvkfgkyeitlteckeeaiagtilnaltvin
-TQRSMDSLLVYHFQYHNWSAHGMPPRMNGLVFLHEQVQKIQSTEDhgPTVVHCSDGAGRTGVFLALAISIERLEAEDTVDIFQTVRWLRSQRPALVGSI
. | . | . | | | . | .. |.. |.|.. | | .|||| | ||| |. . . |. . ..... || .|. | | |
tedasseplymnhvqvpwwpdqlapedarpmielykwvkkvnpkek..picvhcsagvgrtatfvgidyatirimenpniemldivremramrfqavqsh
EQYSCCYQAVKSY
|. | . |
mqflflyvvlmey
|
|||||||||
subfamily_Cele-PTP-11_pd | Subfamily Cele-PTP-11 | 345-544 | 2.9e-15 | 50.8 | In-house | 67-277 (312) | alignment | ||
Range on Protein: 345-544
Range on HMM: 67-277/312.0
SEYINASYIDSYNEAHEYIATQAPMENTINEFWQMVWEQKCTAIVMLTELQDRGQIESELYWPR-DGCVR------YGKYI-VTKIDEEELDDHTQRSMD
|| | .. ...||.|.|||. |||.. .|.|..|. . . | .. | | | | .| .| | |.| .
nfyihanfvkictkperfvctqgplentcthfwqlalslgstsiillcgfvedgsekcakyisdivgfvdledhrvyteycteieiggkskdkithrvlk
SLL--------VYHFQYHNWSAHGMPPRMNGLVFLHEQVQKiqsteDHGPTVVHCSDGAGRTGVFLALAISIERLEAEDTVDIFQTVRWLRSQRPALVGS
.. . |.|. | |||| . | |.| |. | . ||| | |||| . . | | .. .. || .| |
vvvkatgqesklnhyqwaswpdhgmpdscdtalrllsavkk.....dkkpviahcsagvgrtgtlaliesmiaalrhprkqnvkdsfvllrkdrarsvrv
IEQYSCCYQAVKSYLS
. || . ..| .|
fpqyvyalrcvlefly
|
|||||||||
subfamily_Cele-PTP-19_pd | Subfamily Cele-PTP-19 | 348-531 | 5e-23 | 76.3 | In-house | 78-269 (301) | alignment | ||
Range on Protein: 348-531
Range on HMM: 78-269/301.0
INASYIDSYNEAHEYIATQAPMENTINEFWQMVWEQKCTAIVMLTELQDRGQIESELYWPRDG--CVRYGKYIVTKIDEEE-LDDH-TQRS---------
| | .|.. ..| .||||.|..|| ..|| |. . ||||.. .. . | | | . .. |.. .. ..| |... ..|.
ihanwiptsGhphrfiatqgPlkntsedfwamlvqydvekivmlgqkvekleekceeylpvkisekldigrfkikiknkelilnkkiskrtlevedstgk
MDSLLVYHFQYHNWSAHGMPPRMNGLVFLHEQVQKiqsTEDhgPTVVHCSDGAGRTGVFLALAISIERLEAEDTVDIFQTVRWLRSQRPALVGSIEQ
... | |.||..|...|.| | | | |.| .|. | |||||.| ||. |.. . ..||. |... .... || .| | .|
fatrtvthyqysewtdrgvPkshaelfdlmelvkk...sek..PivvhcsaGiGrsvafigteylareveadptieltealkhlrehrwngvqtnsq
|
|||||||||
0049260 | (Phosphotyrosine protein) phosphatases II | 352-537 | 4.1e-35 | 116.1 | In-house | 1-144 (152) | alignment | ||
Range on Protein: 352-537
Range on HMM: 1-144/152.0
YIDSYNEAHEYIATQAPMENTINEFWQMVWEQKCTAIVMLTELQDRGQIESELYWprdgcvrygkyivtkideeelddhtqrsmdsllvyHFQYHNWSAH
.|| |. .|.||||.|..||...||.|..|...|.|||||||...| . | |. ......| |
fidgyampfefiatqgpgpntladfwrmlkelgittivmltellelgklkceqyi...................................qylhlpwpDh
GMPPRMNGLVFLHEQVQKIqSTEDHGPTVVHCSDGAGRTGVFLALAISIerleaeDTVDIFQTVRWLRSQRPALVGSIEQYSCCYQ
| |. | ||.. ..|. ...||..|||| | ||||.. |. . . |.....|...|..|| | . .|. .|.
gvpdlsqlllflllfiekl.aldkggpvlVHCsaGvgRtgtlvaaylml......lgvsleeavalvrekRpgavpnpgqlrflye
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 355-428 | 2.4e-09 | 31.0 | In-house | 231-302 (440) | alignment | ||
Range on Protein: 355-428
Range on HMM: 231-302/440.0
SYNEAHEYIATQAPMENTINEFWQMVWEQKCTAIVMLTELQDRGqieSELYWPRDG-CVRYGKYIVTKIDEEELD
| .|||| |.. |. .||..| . . ..|.|| .|.|. .||| . | .| . | . |...
gyskknafiatqmpldstvldfwrlvhdyristiimlnqlndkt...csiywpvntrsvtfgpftvghkgsenmn
|
|||||||||
subfamily_Anemone-PTP-3_pd | Subfamily Anemone-PTP-3 | 360-537 | 4.9e-28 | 92.7 | In-house | 5-198 (199) | alignment | ||
Range on Protein: 360-537
Range on HMM: 5-198/199.0
HEYIATQAPMENTINEFWQMVWEQKCTAIVMLTELQDRGQIESELYWPR--DGCVRYGKYIVT------KIDE----EELDDHTQRSMDSLLVYHFQYHN
. ||||| |. .|. .||||||| |||. . | . . .||| |. .|| || | | | . | . . |.|.
rryiatqhplretmadfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyqfts
WSAHGMPP--RMNGLVFLHEQVQKIQSTEDHGPTVVHCSDGAGRTGVFLALAISIERLEAEDT--VDIFQTVRWLRSQRPALVGSIEQYSCCYQ
| . | . |.| .| | | | .|||||| | ||||.|| | . | | ||.|. . || | .. |...| ||
wkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiisslqhynfiyq
|
|||||||||
subfamily_Nvec-PTP-3_pd | Subfamily Nvec-PTP-3 | 360-537 | 5.4e-28 | 92.5 | In-house | 4-197 (198) | alignment | ||
Range on Protein: 360-537
Range on HMM: 4-197/198.0
HEYIATQAPMENTINEFWQMVWEQKCTAIVMLTELQDRGQIESELYWPR--DGCVRYGKYIVT------KIDE----EELDDHTQRSMDSLLVYHFQYHN
. ||||| |. .|. .||||||| |||. . | . . .||| |. .|| || | | | . | . . |.|.
rryiatqhplretladfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyqfts
WSAHGMPP--RMNGLVFLHEQVQKIQSTEDHGPTVVHCSDGAGRTGVFLALAISIERLEAEDT--VDIFQTVRWLRSQRPALVGSIEQYSCCYQ
| . | . |.| .| | | | .|||||| | ||||.|| | . | | ||.|. . || | .. |...| ||
wkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiisslqhynfiyq
|
|||||||||
subfamily_hpo-7_pd | Subfamily hpo-7 | 370-522 | 7.2e-08 | 26.6 | In-house | 44-206 (263) | alignment | ||
Range on Protein: 370-522
Range on HMM: 44-206/263.0
ENTINEFWQMVWEQKCTAIVMLTELQDRGQIESELYWP--RDGCVRYGKYIVTKIDEEEldDHTQRSMDSLL----------VYHFQYHNWSAHGMPPRM
.||..|.|.. .| . .|||.. .. |. . . |.| .|. .. . |. . . | .. . | | |..| | .. | .
vqtidkfyqtivqtktevvvmLcDfneegvekcssyfPlekdekqklanvnvcttkvqs..dvllktlellstlgeKkkthtvkhysykgWiekndpela
NGLVflheqvQKIQSTEDHGPTVVHCSDGAGRTGVFLALAIS----IERLEAEDTVDI--FQTVRWLRSQR
. . . .. . . . ||||| | ||. | . | |. .||.. . .. |||.|
reil......nilkvarnskslvvhcstGiGrsaafsvaElvyqkmirsldttstveldylsLleelrssr
|
|||||||||
subfamily_Cele-PTP-9_pd | Subfamily Cele-PTP-9 | 372-523 | 3.1e-10 | 34.6 | In-house | 40-201 (255) | alignment | ||
Range on Protein: 372-523
Range on HMM: 40-201/255.0
TINEFWQMVWEQKCTAIVMLTELQDRGQIESELYWP--RDGCVRYGKYIVTKIDeeELDDH---TQRSM-------DSLLVYHFQYHNWSAHGMPPRMNG
|...|.|.. .| . .|||..... |. . . |.| .|. .. . || . | | . . | |..|. | .. | .
tvdkfyqtivqtktevvvmlcdfaeegvekcssyfplekdeklkladvnvtttk..ssadvvlrtleitstlgekkkthtvkhysykGWieknaPelare
LVFLHEQVQKIQstedhgPTVVHCSDGAGRTGVFLALAIS----IERLEAEDTVDI--FQTVRWLRSQRP
. .. |.. . . ||||| | ||. | . | |. .||.. . .. |||.|.
ilnilkvvrdsk......svvvhCstGiGrsaafvlaelvyqkmirsldttetveldylslleelrskrk
|
|||||||||
0048179 | (Phosphotyrosine protein) phosphatases II | 417-537 | 5.6e-18 | 60.5 | In-house | 32-139 (144) | alignment | ||
Range on Protein: 417-537
Range on HMM: 32-139/144.0
YIVTKIDEEELDDHTQRsmdsllVYHFQYHNWSAHGMPPRMNGLVFLHEQVQKIQSteDHGPTVVHCSDGAGRTGVFLALAISIerleaEDTVDIFQTVR
.... ..| | .. .. ...... .| || |. .. | . | ...... ..||..|||| | ||||.. |. . . . ........
tvinlteeyepeflere......giqylhlpwpDhgvpdllellleflefieeale..eggpvlVHCsaGvgRtgtlvaaylmk.....klglsleeala
WLRSQRPALVGSIEQYSCCYQ
..||.|| | . .|. ...
lvrsrrpgavpnpgqlrfLle
|
|||||||||
subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 425-546 | 1.8e-08 | 28.1 | In-house | 202-347 (349) | alignment | ||
Range on Protein: 425-546
Range on HMM: 202-347/349.0
EELDDHTQRSMDS---LLVYHFQYHNWSAHGMppRMNGLVFLH-----------EQVQKIQSTEDHGPTVVHCSDGAGRTGVFLALAISIE--RLEAED-
.. ||... ... .. .|. || .. .| .|. .. |.. . .|||| | |||||. | . .. ..
pddddddaillavekPyellqlqvknwldlsl..llnPisilqalevkndliddlfarlyldtdqlstllvhcsaGcGrtGvlvtldlllsileplqnes
---------TVDIFQTVRWLRSQRPALVGSIEQYSCCYQAVKSYLSWR
|. .| || || ..| . |. .|.|. |.. .
nkiklqallkDlisiivnelrkqrismvqnlaqfiaiyealLkyfalk
|
|||||||||
0048076 | (Phosphotyrosine protein) phosphatases II | 431-542 | 1.5e-18 | 62.3 | In-house | 38-142 (145) | alignment | ||
Range on Protein: 431-542
Range on HMM: 38-142/145.0
TQRSMDSLLVYHFQYHNWSAHGMPPRMNGLVFLHEQVQKIQSTEdhGPTVVHCSDGAGRTGVFLALAISIErleaEDtVDIFQTVRWLRSQRPALVGSIE
. .. . |.....| .| || |. .. | . |....... . ||..|||| | ||||.. |. . .. .. |.........||||| | . .
selellerlgiqylylpwpDhgvpdllellleflefieealkeg..gpvlVHCsaGvgRtgtlvaaylmll....lg.vsleealelvrsqrpgavpnpg
QYSCCYQAVKSY
|. .|.... .
qlrflyefelel
|
|||||||||
subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 431-546 | 1.8e-12 | 41.7 | In-house | 208-347 (350) | alignment | ||
Range on Protein: 431-546
Range on HMM: 208-347/350.0
TQRSMDSLLVYHFQYHNWSAHGMPPRMNGLVFLHE--------QVQKIQS-TEDHGPTVVHCSDGAGRTGVFLALAISIE---RLE-----------AED
| . | . ||..|..|| .. . . .. | . . . .. | .|||| | ||||....| .. || |
tlaasdPyvvyqlqvknWkDlslllnPesilqalevkndliddlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaak
TVD-IFQTVRWLRSQRPALVGSIEQYSCCYQAVKSYLSWR
| | |...| ||.|| .| ...|. .|.|.. | . |
trDlisiivnelrkqrismvqnldqfifiYeallfyfaLr
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 436-541 | 1.4e-15 | 51.6 | In-house | 87-192 (440) | alignment | ||
Range on Protein: 436-541
Range on HMM: 87-192/440.0
DSLLVYHFQYHNWSAHGMPPRMNGLVFLHEQVQKIQSTEDHGPTVVHCSDGAGRTGVFLALAISIERLEAEDTVDIFQTVRWLRSQRPALVGSIEQYSCC
.| . ...|. | .|.| .. . ..|.. | || .|||| ||||||| .|. . . | .||| . .|..|| .| . |||.
esrtlkqyhyqgwpdkgvpkfagpvlkmiqdvnesqekagngpllvhcsagagrtgviiavdsilreakrsdqidifsfinsmrnnrpqmvqtpeqyafv
YQAVKS
..||
heavle
|
|||||||||
subfamily_Cele-PTP-18_pd | Subfamily Cele-PTP-18 | 438-544 | 1.3e-09 | 32.2 | In-house | 186-288 (305) | alignment | ||
Range on Protein: 438-544
Range on HMM: 186-288/305.0
LLVYHFQYHNWSAHGMPPRMNGLVFLHEQVQkiqstEDHGPTVVHCSDGAGRTGVFLALAISIERLEAEDTVDIF-QTVRWLRSQRPALVGSIEQYSCCY
. | |. . .| |.|. . .. | |. . .||.||||| | |||| . | ...| | . .. . .. .| || . . .|| .
rkvthyhwidwpdrgvpaadlailellekar.....pskgpivvhcsagigrtgsvvmleyildqllagqiiedtdkilqkireqrnnsiqtdaqylfvh
QAVKSYLS
| . |.
qvilnyfr
|
|||||||||
PTPc_DSPc_SM00012 | 440-540 | 2.6e-29 | 96.9 | In-house | 2-104 (105) | alignment | |||
Range on Protein: 440-540
Range on HMM: 2-104/105.0
VYHFQYHNWSAHGMPPRMNGLVFLHEQVQKIQSTED-HGPTVVHCSDGAGRTGVFLALAISIERLEAE-DTVDIFQTVRWLRSQRPALVGSIEQYSCCYQ
|.|..|..|. ||.| ... .. | ..|.| .. .. ..|.|||||.|.||||.| ||.| ...||.| ..|||||.|. ||.||| .| . |||. .|.
vkhyhytgwpdhgvPeesdsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgmvqteeqylflyr
AVK
|..
all
|
|||||||||
subfamily_ptpA1_pd | Subfamily ptpA1 | 441-504 | 7.3e-07 | 23.2 | In-house | 189-257 (418) | alignment | ||
Range on Protein: 441-504
Range on HMM: 189-257/418.0
YHFQYHNWSAHGMPPRMNGLVF-----LHEQVQKIQSTEDHGPTVVHCSDGAGRTGVFLALAISIERLE
..|| | | .| . . . | | | |.. | .|||| | |||| | . | ...|.
tqyqyegwpdhnipdhtqpfrqllhsitnrqnqiipssdrnvpiivhcsagvgrtgtfctavimmkkld
|
|||||||||
0038934 | (Phosphotyrosine protein) phosphatases II | 442-537 | 1.2e-09 | 33.5 | In-house | 79-171 (194) | alignment | ||
Range on Protein: 442-537
Range on HMM: 79-171/194.0
HFQYHNWSA--HGMPPRMNGLVFLHEQVQKIQSTEDHGPTVVHCSDGAGRTGVFLALAISI-ERLEAEDTVDIFQTVRwlrsqrPALVGSIEQYSCCYQ
..|... .| .| .. | . |... . .| .||| | ||||...| .. .. ||. ...|. .| | . ...... ..
gieylklpfpddgtvPsleillrfldlvdeflnedpggvvaVHCkaGlgRtGtlvaaYLiyrlgmsaeeAialfrekR......pgaipnqdyleallk
|
|||||||||
subfamily_Cele-PTP-7_pd | Subfamily Cele-PTP-7 | 445-526 | 6.5e-06 | 19.8 | In-house | 195-271 (302) | alignment | ||
Range on Protein: 445-526
Range on HMM: 195-271/302.0
YHNWSAHGMPPRMnglvflHEQVQKIQSTEDHG-PTVVHCSDGAGRTGVFLALAISIERLEAEDTVDIFQTVRWLRSQRPALV
. | || | . .. .. | . .|||| | |||| ..|. |. ... |. . | .|. | |
fsawpdhGapkea......ytaldilkfcesykknvlvhcsaGvGrtGtlvaikyGiqlcskkkvtdllsivlpvrqcryGav
|
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subfamily_PTPDC1_pd | Subfamily PTPDC1 | 463-539 | 4.2e-07 | 24.6 | In-house | 101-172 (182) | alignment | ||
Range on Protein: 463-539
Range on HMM: 101-172/182.0
LHEQVQKIQSTEDHGPTVVHCSDGAGRTGVFLALA-ISIERLEAEdtvdifQTVRWLRSQRPALVGSIEQYSCCYQAV
. . |. .... ..| . ||| | ||||| .| . .||.|| .... .||.|| . . || .. .
iLdivkvvafalqegkvavhChaGlGrtGvliacylvyakrltae......kaiklvrskrpksiqtreqvelvkefa
|
|||||||||
PTEN_1 | 468-522 | 7.9e-07 | 24.1 | In-house | 122-177 (196) | alignment | |||
Range on Protein: 468-522
Range on HMM: 122-177/196.0
QKIQSTEDHGPTVVHCSDGAGRTG-VFLALAISIERLEAEDTVDIFQTVRWLRSQR
. ..| .... .||| | ||.| | |. .. ..| |........ |. .. .
ewllsdpngnvVlVHCkaGlgRsGtvvaayLmykgkltadeAlelvrekRppgapn
|
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subfamily_CG42327_pd | Subfamily CG42327 | 472-542 | 5.8e-18 | 59.6 | In-house | 243-314 (319) | alignment | ||
Range on Protein: 472-542
Range on HMM: 243-314/319.0
STEDHGPTVVHCSDGAGRTGVFLALAISIERLEAE-DTVDIFQTVRWLRSQRPALVGSIEQYSCCYQAVKSY
|..|| |||||||.||||. .| |.|..|| .||| |.| .| .| | ..||| |. . |
tresqGPlvvhcsdGvGrtGlviasdiairsleeskrsvdiPqlvssvrrdrasavltkeqyefiykvlsey
|
|||||||||
subfamily_Sponge-PTP-7_pd | Subfamily Sponge-PTP-7 | 480-536 | 1.3e-13 | 45.2 | In-house | 2-58 (69) | alignment | ||
Range on Protein: 480-536
Range on HMM: 2-58/69.0
VVHCSDGAGRTGVFLALAISIERLEAEDTVDIFQTVRWLRSQRPALVGSIEQYSCCY
||||| |.|||| |.|. . . |. .| |||| |...| || .| .| .
vvhcssgtgrtgtfiaimvemarikseklvdifnnvqymrkcrpmmvmneieyifih
|
|||||||||
subfamily_Sponge-PTP7_pd | Subfamily Sponge-PTP7 | 480-538 | 1.7e-13 | 44.7 | In-house | 1-59 (69) | alignment | ||
Range on Protein: 480-538
Range on HMM: 1-59/69.0
VVHCSDGAGRTGVFLALAISIERLEAEDTVDIFQTVRWLRSQRPALVGSIEQYSCCYQA
||||| |.|||| |.|. . . |. .| |||| |...| || .| ..| ..|
vvhcssGtGrtGtfiaimvemarikseklvdifnnvqymrkcrpmmvmneneymfihda
|