Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
---|---|---|---|---|---|---|---|---|---|
subfamily_PTPN14_pd | Subfamily PTPN14 | 1-125 | 5.9e-65 | 214.2 | In-house | 177-300 (300) | alignment | ||
Range on Protein: 1-125
Range on HMM: 177-300/300.0
MPTKQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQRTSTTRSSvHESKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQR
.|.|..|||.|.|.||||||.||.|...||..|..|.|.|..|.....| .||||||||||.||||||||.||.||.||....|..|.|...| |||.||
lpskeertvwhlqytDWpdhgvPeDvkgflsyLeevqsvrrktnseves.keskPPvlvhCsaGvGrtGvlilsdlliatlehneeidikkvlarLreqr
MLLVANFGQYRFVYSTVIHYIKNSR
||||....||.|||...|.|.||||
mllvqtlaqYkfvYkvlikylknsr
|
|||||||||
0041856 | (Phosphotyrosine protein) phosphatases II | 2-123 | 6e-28 | 93.1 | In-house | 72-173 (182) | alignment | ||
Range on Protein: 2-123
Range on HMM: 72-173/182.0
PTKQQRTVYHVQFTDWPDHRVPDdPTSFLEFLDQVESlrqrtsttrssvheSKPPVLVHCTAGVGRTGVIILTDLMIACiqnnkRINIHHALVRLRRQRM
|.. .|........ |||| ||| . ..|.|...|.. .. ||||||.|||||||.... .||. . .... .|. .|..|.
pellerlgiqylylpwpDhgvpd.ldelldfieevle..............eggpvlVHCsaGvgRtgtlvaaylmkkl.....gvsleeavklvrsrRp
LLVANFGQYRFVYSTVIHYIKN
| . ||.|.. . .....
gmvitpnqyfflqlallellll
|
|||||||||
0050432 | (Phosphotyrosine protein) phosphatases II | 3-123 | 4.7e-38 | 126.6 | In-house | 193-301 (308) | alignment | ||
Range on Protein: 3-123
Range on HMM: 193-301/308.0
TKQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRqrtsttRSsvheskPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRML
... |||.| ..|.|||| ||..|...|.||..|.. . .. .|..||| |||||||..|. ||.. ... ...... .|. .||.||.
dgesrtvthfhytnWpdhgvPpspeilldflelvrksl......pg......gpivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkklReqRpg
LVANFGQYRFVYSTVIHYIKN
| .. ||.|.| ....|.|.
mvqtpeqylflyralleylkl
|
|||||||||
0046845 | (Phosphotyrosine protein) phosphatases II | 3-123 | 7.4e-38 | 125.9 | In-house | 161-276 (284) | alignment | ||
Range on Protein: 3-123
Range on HMM: 161-276/284.0
TKQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQRtsttrssvHESKPPVLVHCTAGVGRTGVIILTDLMIACIQNNK---RINIHHALVRLRRQ
|.. |||.| ..|.|||| ||..|...||||..|..|... .....|..||| |||||||..|. ||.. ...... .... .|. |||.|
tgesrtvthfhytswpdhgvppspedlleflrlvrellen........lpgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreq
RMLLVANFGQYRFVYSTVIHYIKN
|. | .. |||||| ....|.|.
Rpgmvqtleqyrfvyealleylkl
|
|||||||||
0036941 | (Phosphotyrosine protein) phosphatases II | 3-123 | 1.4e-37 | 125.0 | In-house | 164-279 (297) | alignment | ||
Range on Protein: 3-123
Range on HMM: 164-279/297.0
TKQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQRTsttrssvhESKPPVLVHCTAGVGRTGVIILTDLMIACIQ---NNKRINIHHALVRLRRQ
....|||.| ..|.|||| ||..|.|.|.|...|.. .. . |..|||||| |||||.|..|. |||. ... .....| |. ||.|
ngesrtvthfhytgwpdhgvpespaslldfielvrkvlkll........psggpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReq
RMLLVANFGQYRFVYSTVIHYIKN
|. | ...||||.| ......|.
Rpgavqtleqyrflyeallellkk
|
|||||||||
0051299 | (Phosphotyrosine protein) phosphatases II | 3-122 | 1.7e-37 | 124.9 | In-house | 178-287 (288) | alignment | ||
Range on Protein: 3-122
Range on HMM: 178-287/288.0
TKQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQrtsttrssvhESKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRML
... |||.| ..|.|||| |||.|...|.|| .| . .. ...||.||| |||||||..|. ||.. .......... .|. |||.||.
dgesrtvthfhytnwpdhgvpdspellldflrlvrkala..........sgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlreqRpg
LVANFGQYRFVYSTVIHYIK
.| .. |||||| ....|.|
mvqtpeqyrfvyealleylk
|
|||||||||
0039614 | (Phosphotyrosine protein) phosphatases II | 3-123 | 1.9e-37 | 124.7 | In-house | 179-291 (297) | alignment | ||
Range on Protein: 3-123
Range on HMM: 179-291/297.0
TKQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQRTsttrssvhESKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRML
... |||.|.|.|.|||| ||......||||..|.. .... ... ||||||.|||||||..|. .||. ... ...... .|. .||.||.
ngesrtvthfqytgwpdhgvppslellleflelvrealael........pkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpg
LVANFGQYRFVYSTVIHYIKN
| ...||||.| .....|.
avqtpsqyrflydallellkr
|
|||||||||
0045450 | (Phosphotyrosine protein) phosphatases II | 3-123 | 7.2e-37 | 123.2 | In-house | 191-306 (307) | alignment | ||
Range on Protein: 3-123
Range on HMM: 191-306/307.0
TKQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQRtsttrssvHESKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKR---INIHHALVRLRRQ
|.. |||.| ..|.|||| ||... ..|.|...|.. ... . .. ||||||.|||||||..|. .||. ...... ... .|. .||.|
tgesrtvthfhytgwpdhgvppsfeelldfieevrkalee........lpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreq
RMLLVANFGQYRFVYSTVIHYIKN
|. | |..||||.| .......
Rpgavqnpeqyrflyeallelllk
|
|||||||||
0040438 | (Phosphotyrosine protein) phosphatases II | 3-123 | 1e-36 | 122.2 | In-house | 168-278 (317) | alignment | ||
Range on Protein: 3-123
Range on HMM: 168-278/317.0
TKQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQrtsttrssvhESKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRML
....|||.| ..|.|||| ||..|...|.||..|.. .. ... ||||||.|||||||..|. .||. ... ...... .|. .||.||.
dsesrtvthfhytgWpdhgvppspdllldfleavreale..........dpggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpg
LVANFGQYRFVYSTVIHYIKN
| ...||||.| ...|.|.
avqtpeqyrflydalleylkr
|
|||||||||
0047943 | (Phosphotyrosine protein) phosphatases II | 3-122 | 2.3e-36 | 121.1 | In-house | 162-273 (273) | alignment | ||
Range on Protein: 3-122
Range on HMM: 162-273/273.0
TKQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQRTSTTrssvheskPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRML
|.. |||.|...|.|||| ||....|.|||...|.. .. . .||.||| |||||||..|. ||.. ... ...... |. .||.||.
tgesrtvthfhytgwpdhgvppslesllefielvrkalealpsn........gpvvVHCsaGvgRtgtfialdllldqlekeggvdvleavkllrsqRpg
LVANFGQYRFVYSTVIHYIK
| .. ||||.| ....|.|
mvqtpeqyrflyealleylk
|
|||||||||
0040439 | (Phosphotyrosine protein) phosphatases II | 3-123 | 2.6e-35 | 117.6 | In-house | 136-248 (249) | alignment | ||
Range on Protein: 3-123
Range on HMM: 136-248/249.0
TKQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQRTsttrssvhESKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRML
... |||.|.|.|||||| ||... ..|.|...|.. .... ... ||||||.|||||||..|. .||. ... ...... .|. ||.||.
dgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleel........pkggpvlVHCsaGvgRtGtfiaaylmleqlekelgvdleeavkllrsqRpg
LVANFGQYRFVYSTVIHYIKN
| |..||||.| .......
avqnpeqyrflyeallelllk
|
|||||||||
0043336 | (Phosphotyrosine protein) phosphatases II | 3-122 | 4.2e-35 | 117.0 | In-house | 169-278 (278) | alignment | ||
Range on Protein: 3-122
Range on HMM: 169-278/278.0
TKQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQrtsttrssvhESKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRML
... |||.|.....|||| ||......|.|| .| . .. |. ||||||.|||||||..|. .|.. ............|. .||.||.
dgesrtvthyhylgwpdhgvpeslsllldflkavreale..........dsngpvlVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqRpg
LVANFGQYRFVYSTVIHYIK
| .. ||||.| ...|.|
avqtpsqyrflyealleylk
|
|||||||||
0042113 | (Phosphotyrosine protein) phosphatases II | 3-122 | 1e-34 | 115.4 | In-house | 134-244 (245) | alignment | ||
Range on Protein: 3-122
Range on HMM: 134-244/245.0
TKQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQRtsttrssvhESKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRML
....|.|.|.....|||| |||.. ..|.||. |.. ... |. ||||||.|||||||..|. .||. ... ...... .|. .||.||.
ddesrevihyhylpwpdhgvpdllellldflefvrkalae.........dsngpvlVHCsaGvgRtGtfiaaylmleqlekelgvsleeavkelrsqRpg
LVANFGQYRFVYSTVIHYIK
| ...||||.| .....|
avqtpsqyrflyeallellk
|
|||||||||
0045098 | (Phosphotyrosine protein) phosphatases II | 3-122 | 1.7e-34 | 114.9 | In-house | 150-273 (278) | alignment | ||
Range on Protein: 3-122
Range on HMM: 150-273/278.0
TKQQRTVYHVQFTDWPDHRVPDDP--TSFLEFLDQVESLRQRTSTTRSS---VHESKPPVLVHCTAGVGRTGVIILTDLMIACIqnNKRINIHHALVRLR
. ..|.|.|.... |||| ||..| .||||.|..... ... . .| ...|. |||||| |||||||.... .||. .. ...... .|. ||
dlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllsslllldsggpvlVHCsaGvgRtGtlvaaylmlell..eggvdlleavkelr
RQRML-LVANFGQYRFVYSTVIHYIK
.||. | |..||||.| ......
sqRpglavqnleqyrflyefllelll
|
|||||||||
subfamily_PTPN3_pd | Subfamily PTPN3 | 3-121 | 1.8e-34 | 114.0 | In-house | 167-275 (280) | alignment | ||
Range on Protein: 3-121
Range on HMM: 167-275/280.0
TKQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRqrtsttrssvHESKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRML
||..|.. ..|...|||| ||||...||||...|..|| . .. ||.|||.||.|||||.|| .. .| |.... ... . . ..| ||.
tkeerkilqlqylaWpdhgvPddsadflefvervrklr..........sgkeePvvvhCsaGigrtGvlilletalalieaaepvypldivrtmrdqram
LVANFGQYRFVYSTVIHYI
|| . .||.|| ....
lvqtasqykfvCeailkvy
|
|||||||||
0037934 | (Phosphotyrosine protein) phosphatases II | 3-121 | 7.5e-33 | 109.5 | In-house | 129-242 (243) | alignment | ||
Range on Protein: 3-121
Range on HMM: 129-242/243.0
TKQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQRTSTTRssVHESKPPVLVHCTAGVGRTGVIILTDLMIACIqnnkRINIHHALVRLRRQRML
....|.|.|.... |||| |||.|...|.|||.| . ... . . . |. ||||||.|||||||..|. .||. .. .... .|. .||.||.
ddltrlvihyhylpwpdhgvPdspedlldfldevrefieellsll..aldsggpvlVHCsaGvgRtGtliaaylmllll....gvdleeavkllreqRpg
-LVANFGQYRFVYSTVIHYI
| ...||||.| .....
kavqtpsqyrflyeallell
|
|||||||||
subfamily_PTPN9_pd | Subfamily PTPN9 | 3-124 | 2.5e-30 | 100.6 | In-house | 169-293 (297) | alignment | ||
Range on Protein: 3-124
Range on HMM: 169-293/297.0
TKQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQR---TSTTRSSVHESKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQ
|...|.| | ||. |||. ||.. .|.|..|..| . . . . .. | |.||..|||.||.|||| | |. .. ... ... ... .|| |
teesrkvthfqflsWPdyGvPssaaslldvlekvrekqalavkelgdewkghpsgPPivvhcsaGiGrtGtfitldiclsrleevgtvdvvetvkllrtq
RMLLVANFGQYRFVYSTVIHYIKNS
| . || | | .|. | ...
rafsiqtpeqyefcylavleyalel
|
|||||||||
subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 3-122 | 4.6e-29 | 96.4 | In-house | 171-280 (288) | alignment | ||
Range on Protein: 3-122
Range on HMM: 171-280/288.0
TKQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQRTsttrssvhesKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRML
.|..... . |.. |||| ||.. . .||.|.||. | |..|||.|||||||. | | .| ..... |.. .. .||.||.|
kkteleitqyqylaWpdhgvPeskapllellrqvkvanqad..........tgpiivhCsaGvGrtgtFialdalidaveeedyiDvagtvaklRkqRal
LVANFGQYRFVYSTVIHYIK
|| . || |.|..... |.
lvqtlkqYefiyevllslie
|
|||||||||
0043147 | (Phosphotyrosine protein) phosphatases II | 3-114 | 6.4e-29 | 96.3 | In-house | 59-154 (172) | alignment | ||
Range on Protein: 3-114
Range on HMM: 59-154/172.0
TKQQRTVYHVQFTDWPDHRVPdDPTSFLEFLDQVES--LRQRtsttrssvhesKPPVLVHCTAGVGRTGVIILTDLMIaciqnnKRINIHHALVRLRRQR
.. .|........ |||| || .. .||||..... .... . ||||||.|||||||.... .||. .......|. .|..|
ellerlgiqylylpwpDhgvp.llellleflefidellalsp...........ggpvlVHCsaGvgRtgtlvaaylml......lglsleeavalvrekR
MLLVANFGQYRFVY
. | |..||||.|
pgavqnpsqyrfly
|
|||||||||
subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 3-123 | 8.1e-28 | 92.3 | In-house | 166-278 (281) | alignment | ||
Range on Protein: 3-123
Range on HMM: 166-278/281.0
TKQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQRTSTtrssvheskPPVLVHCTAGVGRTGVIILTDLMIACI-QNNKRINIHHALVRLRRQRM
. ..|.| ....| |||| ||.... .||| ..|..|... . |...|| |||||||. | | .. . ......... . ||..|.
sgetreveqlaytaWPdhGvPattkellefrkevlkltekktk.........aplvihCsaGvGrtGtyialDrlvkaveaeleeldvkavvaelrkern
LLVANFGQYRFVYSTVIHYIKN
|.| ||.||| .|......
lmvqtvvqyefvykavldaldk
|
|||||||||
0051429 | (Phosphotyrosine protein) phosphatases II | 3-122 | 3.1e-27 | 91.3 | In-house | 116-226 (272) | alignment | ||
Range on Protein: 3-122
Range on HMM: 116-226/272.0
TKQQRTVYHVQFTDWPDHRVPDDPtsFLEFLDQVESlrqrtsttrssvhesKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRIN--------IHHALV
... |.|.| ..|||||| ||... .||.|... . . ||||||.||..|||.... .|... . . .. . .|.
agearevmhlhytdwpdhgvpqea..llellellld...............ggpvlvHCsaGkdRTGtvvallllllgvsletivddYlltnlyleeave
RLRRQRMLLVANFGQYRFVYSTVIHYIK
.||.||. | . .||.|.| ......
elraqrpgavqteeqylflyeallellr
|
|||||||||
subfamily_PTPN1_pd | Subfamily PTPN1 | 3-122 | 1.5e-26 | 87.8 | In-house | 158-272 (290) | alignment | ||
Range on Protein: 3-122
Range on HMM: 158-272/290.0
TKQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVeslrqRTSTtrsSVHESKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKR---INIHHALVRLRRQ
|.. |...| .| ||| ||. |..||.|| .| | | |. . . |...||.||.||.| ..| | ... |.... ..|.. |. ||..
tqetreilhfhyttwpdfgvpespaaflkflfkv.....resG...slssdvGpavihcsaGiGrsGtfclvdtclvliekkddlssvdikkvllelrky
RMLLVANFGQYRFVYSTVIHYIK
|. |. | || | .... .|
rlGliqtadqlrfsylaileGak
|
|||||||||
subfamily_PTPN23_pd | Subfamily PTPN23 | 3-123 | 1.4e-25 | 84.7 | In-house | 167-282 (288) | alignment | ||
Range on Protein: 3-123
Range on HMM: 167-282/288.0
TKQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLR---QRTSTTrssvheskpPVLVHCTAGVGRTGVIILTDLMIACIQN-NKRINIHHALVRLRR
... ..| |.|.| ||.. ||. | ..|.|||.||| || | | |..||| ||||||||. | .. ... | ..| . . |||.
adavksvshlqltsWpelGvPasPetllqfldevesayeavqrkskt.........PlvvhCsaGvgRtgvfalvyaavrelekgnglldiiqvvsrlre
QRMLLVANFGQYRFVYSTVIHYIKN
|| | . |..|.|. |......
qRrfmvqekeqlkfsyeavleaarr
|
|||||||||
subfamily_PTPN13_pd | Subfamily PTPN13 | 3-122 | 3.3e-25 | 83.9 | In-house | 162-270 (273) | alignment | ||
Range on Protein: 3-122
Range on HMM: 162-270/273.0
TKQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESlrqrtsttrssVHESKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRML
... | | |..|..|||| || ....|.|. .| . ..... |..|||.||.||.|..| | .. |...| ..... . .||.||
sgesrevahlnfvkwPdhgvPssaaellqfvaevrr...........lqtdagPivvhcsaGiGrsGtlitidvvlglierdkefdvkeivrklreqrqg
LVANFGQYRFVYSTVIHYIK
.| || ||| .... .|
vvqtkdqyifvykailevlk
|
|||||||||
subfamily_PTPRK_pd | Subfamily PTPRK | 3-118 | 1.2e-24 | 81.7 | In-house | 169-274 (314) | alignment | ||
Range on Protein: 3-118
Range on HMM: 169-274/314.0
TKQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQRtsttrssvheSKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRML
...|.| ..||. |||| || |..|... .|.. .. .. ...|||.|| ||||. | | .. |.... .....| || ...
qeeirevrqfqflgWpdhdvPvsatgllklvrrvkksqee..........eaGrivvhCsaGaGrtGtfiaidivldmieregvvdvfnavktlrsrkvn
LVANFGQYRFVYSTVI
.| ||.|.| ..
mveteeqykfiydvil
|
|||||||||
subfamily_PTPRA_pd | Subfamily PTPRA | 3-120 | 1.4e-24 | 81.6 | In-house | 187-294 (330) | alignment | ||
Range on Protein: 3-120
Range on HMM: 187-294/330.0
TKQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQRTSttrssvheSkpPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRML
|..| | . || ||| || .| |..| .|..|.|... . |. |||.||||||| | | ... .. .......... ||| ||
ekksrlvrqfhftswPdvGvPfepiGmlkllkkvkklnqqsa........g..pivvhcsaGvGrtGtfivldavlervkaerkvdvfefvkrlrlqrpq
LVANFGQYRFVYSTVIHY
.| || |.| .. .|
mvqtdeqyefiykvlley
|
|||||||||
subfamily_Sponge-PTP6_pd | Subfamily Sponge-PTP6 | 3-122 | 4.2e-21 | 69.9 | In-house | 170-280 (439) | alignment | ||
Range on Protein: 3-122
Range on HMM: 170-280/439.0
TKQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQRtsttrssvhESKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRML
|...||| ..... |||. || . . |.|| ..| .. | ||.|||.||||||| || |. . .. .....|. . ||.||
tekertvlqfhyiawpdknvpaqashvldflrainsandk.........eeygpvvvhcsagvGrtGtiialdialeqlklenkvdikgivkvlrkqrkq
LVANFGQYRFVYSTVIHYIK
.| .. || |.| .|. |.
mvqalcqyvfiynavlediv
|
|||||||||
subfamily_Cele-PTP-11_pd | Subfamily Cele-PTP-11 | 3-123 | 1.8e-19 | 64.6 | In-house | 172-278 (312) | alignment | ||
Range on Protein: 3-123
Range on HMM: 172-278/312.0
TKQQRTVYHVQFTDWPDHRVPDDPTSFLEFLdqveslrqrtsttrSSVHESKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRML
| |. . | |.. |||| .|| . | .| |.|. | ||. ||.||||||| ..| . |||... .. |.....| ||..|
tgqesklnhyqwaswpdhgmpdscdtalrll..............savkkdkkpviahcsagvgrtgtlaliesmiaalrhprkqnvkdsfvllrkdrar
LVANFGQYRFVYSTVIHYIKN
| | || .. .|.... .
svrvfpqyvyalrcvleflys
|
|||||||||
subfamily_PTPRN_pd | Subfamily PTPRN | 3-121 | 3.5e-19 | 63.6 | In-house | 183-292 (297) | alignment | ||
Range on Protein: 3-121
Range on HMM: 183-292/297.0
TKQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVEslrqRTSTTRSSvheskpPVLVHCTAGVGRTGVIILTDLMIACIQ-NNKRINIHHALVRLRRQRM
|.. ||| | ||.. || . |.||| .|. .. ||. |..|||..|.||||| || ||... .. |.|.| .| || ||
tsetrtvtqfhflswpeegvPasaksllefrrkvn....ksyrGrsc......pivvhcsdGaGrtGvyilidlvlnrllkGvkeidiaatlehlrdqrp
LLVANFGQYRFVYSTVIHYI
||. |..|....|.. .
glvktkdqfefaltavaeev
|
|||||||||
subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 3-123 | 3.2e-17 | 57.3 | In-house | 164-279 (287) | alignment | ||
Range on Protein: 3-123
Range on HMM: 164-279/287.0
TKQQRTVYHVQFTDWPDHRVPDDPTSFLEFldqVESLRQRTSTTRSSvHESKpPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRML
|.. | | ... .|||. .. ... | | . .|. .|.. | |..||. .|.||.|... | .. .. |... ...||| .|
trearvvkqldllswPdkvlaPtavglirf...vldvkqhielarda.sevG.PlvvhddvGiGrsGillatlvlvsrledlGrvdvaavvirlreyraa
LVANFGQYRFVYSTVIHYIKN
|| |.|..| ... | |
lvqavvqlrllyealvtyykt
|
|||||||||
subfamily_Cele-PTP-18_pd | Subfamily Cele-PTP-18 | 3-126 | 2.8e-16 | 54.1 | In-house | 182-292 (305) | alignment | ||
Range on Protein: 3-126
Range on HMM: 182-292/305.0
TKQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQveslrqrtstTRSsvheSKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRIN-IHHALVRLRRQRM
...| | | . |||| || .. ||.| . .|. || |. |||.||.|||| ... . .. . . . |. .. |...| ||
gekarkvthyhwidwpdrgvpaadlailellek..........arp....skgpivvhcsagigrtgsvvmleyildqllagqiiedtdkilqkireqrn
LLVANFGQYRFVYSTVIHYIKNSRL
. || ||. .. |... .|
nsiqtdaqylfvhqvilnyfrkkkl
|
|||||||||
DSPc_SM00195 | 4-122 | 2.7e-35 | 117.3 | In-house | 155-263 (263) | alignment | |||
Range on Protein: 4-122
Range on HMM: 155-263/263.0
KQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQRTsttrssvhesKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLL
...|.|...|...|||| |||...|.||.| .|.. .... ..|..||| |||||||.....|... ....|...| . . .|| ||. .
eetrkvtqyqyknWpdhgvpdstksvlellravkksksts..........sgpivVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgm
VANFGQYRFVYSTVIHYIK
| .. ||.|.| ....|||
vqtleqYlfiyeaileyik
|
|||||||||
PTPc_SM00194 | 4-122 | 2.7e-35 | 117.3 | In-house | 155-263 (263) | alignment | |||
Range on Protein: 4-122
Range on HMM: 155-263/263.0
KQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQRTsttrssvhesKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLL
...|.|...|...|||| |||...|.||.| .|.. .... ..|..||| |||||||.....|... ....|...| . . .|| ||. .
eetrkvtqyqyknWpdhgvpdstksvlellravkksksts..........sgpivVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgm
VANFGQYRFVYSTVIHYIK
| .. ||.|.| ....|||
vqtleqYlfiyeaileyik
|
|||||||||
subfamily_PTPRD_pd | Subfamily PTPRD | 4-123 | 1.9e-34 | 114.3 | In-house | 174-283 (564) | alignment | ||
Range on Protein: 4-123
Range on HMM: 174-283/564.0
KQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQrtsttrssvhESKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLL
...|.| . .||.|||| ||. .||.|.....|..|.. . . |..||| |||||||. | | |. |...| ..| . .||.|| .
sesreVrqFhFtsWPdhgvpesatslLdlirkvralne..........pdagPivVhCSaGVGRTGtfividamlerikeektvDiyqyvkalrkqRnam
VANFGQYRFVYSTVIHYIKN
| . || |..... ....
VqteeQYiFiheailealac
|
|||||||||
subfamily_PTPN6_pd | Subfamily PTPN6 | 4-125 | 2.4e-32 | 107.2 | In-house | 183-301 (306) | alignment | ||
Range on Protein: 4-125
Range on HMM: 183-301/306.0
KQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQRTSTTrssvheSKPPVLVHCTAGVGRTGVIILTDLMIACIQNN---KRINIHHALVRLRRQR
|..|.|.. .|..|||| || || .|.||..|.. ....... .. |..|||.||.|||| .|..|... |... |.|... .|.||
keerevfqyhfksWPdhgvpkdpgavLdfledvnrkqeeleea......eagpivvhCsaGiGRtGtfiviDillkliekkgldadidiqklvksvreqr
MLLVANFGQYRFVYSTVIHYIKNSR
|| ||.||| .. .||....
sglvqteqqykfvykaikkyietkk
|
|||||||||
subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 4-122 | 1.2e-29 | 98.5 | In-house | 175-284 (305) | alignment | ||
Range on Protein: 4-122
Range on HMM: 175-284/305.0
KQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQRtsttrssvhESKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLL
|..||| . |.|||||| ||. .||.|.....|. ... . . |.|||| |||||||| | |... ... . ... . | .||..|| .
kesrtvlqyqltdWPdhGvpqfatsllslikrvqkdqkk.........dkgvpllVhCsagvgRtGvfiavdialerlkkEevvdvfevlkqlRskrmkm
VANFGQYRFVYSTVIHYIK
| . || |.. . .|.
vqtldqYvflhdaldelit
|
|||||||||
subfamily_PTPRB_pd | Subfamily PTPRB | 4-124 | 7.4e-29 | 95.7 | In-house | 176-288 (293) | alignment | ||
Range on Protein: 4-124
Range on HMM: 176-288/293.0
KQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQRTSttrssvheSKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLL
|..|.| . .|| |||| ||......|.|. .|.. ..|. || |..||| |||||||. | | .. |... ..| ...||..|.||
keerkvrqyhftsWpdhgvPektktlldfvrtvreaiekta........skrPivvhCsaGvGRtGtfialdrllqaieeedyvdifgivaelReeRnll
VANFGQYRFVYSTVIHYIKNS
| . || |....|.......
vqtekqYifihqcvldllrkk
|
|||||||||
subfamily_PTPN5_RR_pd | Subfamily PTPN5_RR | 4-123 | 1.8e-28 | 94.4 | In-house | 158-270 (274) | alignment | ||
Range on Protein: 4-123
Range on HMM: 158-270/274.0
KQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVeslrqrtSTTRSSVHESKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLL
...|.|.| .||||||..|||....|.....| ...|.. .. ||.|||.||.||||. | ... . ..... ... . . || .| .
erersvkhywytdWPdhksPddantlldlvlev.......eesreeenaklapvvvhCsaGiGrtGcfiaisiavrqlreeivvdvlkivcnlrldrGGm
VANFGQYRFVYSTVIHYIKN
| . ||.... ....| |.
vqtseqyelihralclylkr
|
|||||||||
0036282 | (Phosphotyrosine protein) phosphatases II | 4-114 | 2.2e-28 | 94.5 | In-house | 64-163 (174) | alignment | ||
Range on Protein: 4-114
Range on HMM: 64-163/174.0
KQQRTVYHVQFTDWPDHRVPDDPTsFLEFLDQVESLRQRtsttrssvhESKPPVLVHCTAGVGRTGVIILTDLMIACIQnNKRINIHHALVRLRRQRMLL
|........ |||| |||... .|||...||. ... .. ||||||.|||||||.... .||. .. .. ... . . .||.||.
dlerlgiqylylpwpDhgvpdlsi.llefvkfveealse.........dpggpvlVHCsaGvgRtGtlvaaylmlrgll.eslvdaldlvrelRlqrpgm
VANFGQYRFVY
| ...||||.|
vqtpsQyrfly
|
|||||||||
0048076 | (Phosphotyrosine protein) phosphatases II | 4-119 | 7.3e-28 | 92.5 | In-house | 42-141 (145) | alignment | ||
Range on Protein: 4-119
Range on HMM: 42-141/145.0
KQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQRtsttrssvhesKPPVLVHCTAGVGRTGVIILTDLMIAciqnnKRINIHHALVRLRRQRMLL
|.........|||| |||.. .||||...|..... . ||||||.|||||||.... .||. .......|| ..|.||.
llerlgiqylylpwpDhgvpdllellleflefieealke...........ggpvlVHCsaGvgRtgtlvaaylmll.....lgvsleealelvrsqrpga
VANFGQYRFVYSTVIH
| |.||.||.| . .
vpnpgqlrflyefele
|
|||||||||
subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 4-123 | 9.4e-28 | 92.2 | In-house | 172-282 (318) | alignment | ||
Range on Protein: 4-123
Range on HMM: 172-282/318.0
KQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQRTSTTrssvheskpPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLL
...|.| ..|.|||. ||....|.|... ||.. |..... |..|||.|||||||| | | .. |.... ..... .||.|| |.
eesrqvrqyhytsWpdegvpesgaslldlvrqvskaqqksgag.........pivvhCsaGvGrtGvfiavdillerikaealvDvfqtvkqlreqrnlm
VANFGQYRFVYSTVIHYIKN
| || |.| ... ...
vqtedqyefiydvllealas
|
|||||||||
subfamily_PTPN12_pd | Subfamily PTPN12 | 4-123 | 4.3e-27 | 89.7 | In-house | 167-279 (290) | alignment | ||
Range on Protein: 4-123
Range on HMM: 167-279/290.0
KQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQrtsttrssvhESKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKR---INIHHALVRLRRQR
|..|.|| ..|.|||| || ..| ||....|..|.. ... |..||| |||||||.|| |.. ....| ..... ...||.||
kesrkvyqfhYtaWPDhgvPssaksllelielvrelqe..........sedaPlvvhCsaGvGrtGtiiaidyvrellkaekipeeldvfdlvlelrkqr
MLLVANFGQYRFVYSTVIHYIKN
|| ||..|| .|......
aalvqtkeqyelvykavaelvqk
|
|||||||||
subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 4-122 | 5.1e-26 | 86.6 | In-house | 182-291 (298) | alignment | ||
Range on Protein: 4-122
Range on HMM: 182-291/298.0
KQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESlRQRTSTTRssvheskpPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLL
...|.| ...|| |||. || || |..|..|. |. . . ||.|.| |||||.| | | .. ..... . ..... .||..|. .
ekerevrqlhftsWpdkgvpenatsvldllrkvra.sqqqagnk........pvivqCsaGvgRsGtfiaidsvlervkkeqvvDvfqvvkvlRkkrpga
VANFGQYRFVYSTVIHYIK
| || |.|. |.....
vqteeqYvfiyeavleald
|
|||||||||
subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 4-122 | 2.8e-25 | 84.1 | In-house | 174-285 (297) | alignment | ||
Range on Protein: 4-122
Range on HMM: 174-285/297.0
KQQRTVYHVQFTDWPDHRVPD-DPTSFLefLDQVESLRQRTSTtrssVHESkpPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRML
|..| | ||..|||. |. | .| | |. .. .|. |. . |. |.||||.||||||||.. | ..| ....| ..| . .||..|.
karrvvkqyqfveWPdkaverkdsassl..lklisevrkdfsq....naeg..PllvhclaGvGrtgvlltidsvvaeakrekevdifglvkklrqerpy
LVANFGQYRFVYSTVIHYIK
|| ||.||| .|. ..
lvqtkeqykfvyvavleall
|
|||||||||
subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 4-122 | 4.9e-25 | 83.2 | In-house | 134-243 (250) | alignment | ||
Range on Protein: 4-122
Range on HMM: 134-243/250.0
KQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQRTSTTrssvheskpPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLL
...|.| ...|. ||| ||. |. ||.|..|.. .|.. .. ||.|.|.|||||.| | | .. ....| ..... . .||..|.
aderivrqlhfvvWPdkgvPevatavLellkkvqasqqqagna.........PvivqCsaGvgrsGafiaidavlerlkkekvvdvfkvikvlrkdrpha
VANFGQYRFVYSTVIHYIK
| || |||. ......
vesleqyvfvyeiilkald
|
|||||||||
subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 4-119 | 1.4e-24 | 82.0 | In-house | 182-289 (319) | alignment | ||
Range on Protein: 4-119
Range on HMM: 182-289/319.0
KQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQRTsttrssvhESKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLL
|..| . | |||. ||| |. .. ....|. |... . . ...|||.|||||||| | | .. ....|...... . ||.|| |
kdirkitqfhflGwpdvGvpdypsdlmrlvkkvrhltske........nhranivvhcsaGvGrtGvyivldvlldrmkeekqvdvynfvrdlrqqrntl
VANFGQYRFVYSTVIH
| .. || |.||...
vqdlvqykfiysalle
|
|||||||||
subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 4-119 | 2.7e-24 | 81.1 | In-house | 146-253 (284) | alignment | ||
Range on Protein: 4-119
Range on HMM: 146-253/284.0
KQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQRTsttrssvhESKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLL
|..|.. | |||. ||| |. .. ....|. |... . . ...|||.|||||||| | | .. ....|...... . ||.|| |
kdirkirqfhflgwpdvgvpdypsdlmrlvkkvrhltske........nhranivvhcsagvgrtgvyivldvlldrmkeekqvdvynfvrdlrqqrntl
VANFGQYRFVYSTVIH
| .. || |.||...
vqdlvqykfiysalle
|
|||||||||
subfamily_PTPRG_pd | Subfamily PTPRG | 4-122 | 3e-24 | 80.2 | In-house | 180-288 (563) | alignment | ||
Range on Protein: 4-122
Range on HMM: 180-288/563.0
KQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVeslrqrtsttRSSVHESKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLL
.....|.. ..|.|||| ||. .. | | . . .. |..||| |||||||. | | .. ||... .|... | ..| || |
dteklvrqyhytkWPdhgvPehslpvLifvkks..........saankaeaGPivvHcsaGvgrtGtyivldtllkqiqqenavnvfgflkhiraqRnfl
VANFGQYRFVYSTVIHYIK
|.. || |.. ... |.
vqteEqYiflhdalleaia
|
|||||||||
subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 4-122 | 1.5e-23 | 78.2 | In-house | 170-278 (315) | alignment | ||
Range on Protein: 4-122
Range on HMM: 170-278/315.0
KQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESlrqrtsttrsSVHESKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLL
...||| |||.|||. |. . .|.|... .| . . .. . ..||||.||||||||.| | ..| |.... ... . . ||..|. |
eesrtvtqfqftewPdkGvdkqtssllklikevka..........dngkkefsllvhcsaGvGrtGvvisidevvaqikrtrsvdvfnfvknlrakrpyl
VANFGQYRFVYSTVIHYIK
| .| |.| .| ...
vqteeeyafiydavledll
|
|||||||||
subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 4-122 | 7.6e-20 | 65.9 | In-house | 161-296 (297) | alignment | ||
Range on Protein: 4-122
Range on HMM: 161-296/297.0
KQQRTVYHVQFTDWPDHRVPDDPTSFLEF--------------LDQVE---SLRQRTSTTRSSVHESKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKR
...| | |||| |||| || | | | || .. . . . . ..||||.|||||.||..|.| ..| .....
sesrvvrhvqflswpdhGvpsdledlvrfqaqvcscciavpmmlalvemftamvflqleslraemprnayllvhcsaGvGrsGvvvlsdvilaklrkkri
INIHHALVRLRRQRMLLVANFGQYRFVYSTVIHYIK
.. | || || || . |. ..|. |.. .|
pdvaailsilreqrarlvqtleqfellydavlkklk
|
|||||||||
subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 4-123 | 2.3e-17 | 57.8 | In-house | 175-285 (290) | alignment | ||
Range on Protein: 4-123
Range on HMM: 175-285/290.0
KQQRTVYHVQFTDWPDHR-VPDDPTSFLEFLDQVESLRQRtsttrssvheSKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRML
.....| . |.| |... |.. |. | . ... |.| . ...||| ..|||..| . .. | . . |.. . | ..| |..
gakqsvtqyqitnwdstgkvtnpqtillvieemyktqrkr..........gntsivvHCSdtvgrsavfcaaattinkcktegvidvfqvlksqRiqkpg
LVANFGQYRFVYSTVIHYIKN
.| ||..... |..|...
svqtvqqyqgifqivltylds
|
|||||||||
subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 4-118 | 3.2e-17 | 57.5 | In-house | 130-236 (237) | alignment | ||
Range on Protein: 4-118
Range on HMM: 130-236/237.0
KQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVeslrqrtSTTRSSVHESkPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLL
|. | .. ||| |||. ||. ...| | .. | || | ..||.|||||||.... | |. ...| ..|. . . .| .
kevrlihqyqftswpdrgvpqqtaallrfrkni.......inrsphvses.gpwiihcsagvgrtgiflvidamlrqakekkvvdiynyvysieedrpyi
VANFGQYRFVYSTVI
. || |.. |..
iqtkdqyvfihqtil
|
|||||||||
subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 4-123 | 6.8e-17 | 56.4 | In-house | 170-280 (287) | alignment | ||
Range on Protein: 4-123
Range on HMM: 170-280/287.0
KQQRTVYHVQFTDWPDHR-VPDDPTSFLEFLDQVESLRQRTSTtrssvheskpPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRML
.....| |.|.|.... |.. |..| . ... . |.|. | ...|||...|||... . . | ... |.. | . | |..
gdkqqvkqyqitnWdstgkvtepqtillvieemyktqrkrgnt..........sivvhCsdtvGrsamfcaaattinkckteGviDvfqvlksqriqkpg
LVANFGQYRFVYSTVIHYIKN
| ||.|.. |..|..
svqtveqykfindivleylds
|
|||||||||
subfamily_Cele-PTP-10_pd | Subfamily Cele-PTP-10 | 4-121 | 2.4e-16 | 54.3 | In-house | 185-289 (305) | alignment | ||
Range on Protein: 4-121
Range on HMM: 185-289/305.0
KQQRTVYHVQFTDWPDHRVPDDPTSFLEFLdqveslrqrtsttrSSVHESKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVR-LRRQRML
.|. .| |.|.|.||| || . ||.| |.. || |..|||.||.|||| |. . .. | .||. ||. || ||
dqkmsvrhlqwtewpdrgvppckltslell..............sairgskvpivvhcsagigrtgtivaieyilekiaenkpcppmpelvkalrdqraf
LVANFGQYRFVYSTVIHYI
. | || |.. .. |.
siqndvqylfihrvmlnyf
|
|||||||||
subfamily_Sponge-PTP9_pd | Subfamily Sponge-PTP9 | 4-122 | 4.8e-15 | 50.0 | In-house | 185-294 (301) | alignment | ||
Range on Protein: 4-122
Range on HMM: 185-294/301.0
KQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQRTsttrssvheSKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLL
|. ..| .| ||||.. | .| |. .|.| .|. .. ||.||| ..|.|.|| . .. . . . ... ..||...
ksswdvlqlqvtdWpqdGvvreprtvLqviddvihrqqki.........gggpvvVHCSdtVsrsGvYcsvsiglEQckaegVVdvfqvtkavrrskpga
VANFGQYRFVYSTVIHYIK
| || ..| . |..
VtTLeqytsiydvidmylq
|
|||||||||
subfamily_Cele-PTP-6_pd | Subfamily Cele-PTP-6 | 4-121 | 3.9e-14 | 47.4 | In-house | 173-277 (307) | alignment | ||
Range on Protein: 4-121
Range on HMM: 173-277/307.0
KQQRTVYHVQFTDWPDHRVPDDPTSFLEFLdqveslrqrtsttrSSVHESKPPVLVHCTAGVGRTGVIILTDL-MIACIQNNKRINIHHALVRLRRQRML
.. ||. |.|...|||. ||. . ...| ..|. . ||.|||.|||||.| |. | . |. .... . || ||
qksrtiqhlqwenwpdrgvpqinltainll..............eavrydtnpvvvhcsaGvGrsGtivaislvqdkmiaGinckdmkklveelrsqrhy
LVANFGQYRFVYSTVIHYI
. . || ... ...|
aiqteaqylylhrvlleyf
|
|||||||||
subfamily_Cele-PTP-7_pd | Subfamily Cele-PTP-7 | 4-106 | 9.4e-12 | 39.0 | In-house | 185-273 (302) | alignment | ||
Range on Protein: 4-106
Range on HMM: 185-273/302.0
KQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQRtsttrssvheskppVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLL
|...|| ..|. |||| |... . |. | || .. |||||.||||||| .. | ...| .. . .. .|. |
kvkktvdilafsawpdhGapkeaytaldilkfcesykkn..............vlvhcsaGvGrtGtlvaikyGiqlcskkkvtdllsivlpvrqcryGa
VAN
| .
vqd
|
|||||||||
subfamily_Cele-PTP-1_pd | Subfamily Cele-PTP-1 | 4-121 | 1.4e-11 | 39.1 | In-house | 155-259 (290) | alignment | ||
Range on Protein: 4-121
Range on HMM: 155-259/290.0
KQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVEslRqrtsttrssvheSKPPVLVHCTAGVGRTGVIILTDLMIACIQ-NNKRINIHHALVRLRRQRML
... || | .. .| . |..|. ..|. ...|. || ||.|||. |. | .. .| | .. .... .| ||.|| |
eeeftvtHsllkgWnklnvqedtktllsliqkvk..a............sktpvivHcvdGiSrsAalaaiilgyQkiaetsgsvkledvlkalrkqral
LVANFGQYRFVYSTVIHYI
.. . .. || .. ..
aitsalelafvdagivlla
|
|||||||||
subfamily_Cele-PTP-9_pd | Subfamily Cele-PTP-9 | 4-119 | 2.2e-07 | 25.2 | In-house | 113-219 (255) | alignment | ||
Range on Protein: 4-119
Range on HMM: 113-219/255.0
KQQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQveslrqrtsttrssVHESKpPVLVHCTAGVGRTGVIILTDL----MIACIQNNKRINIHH--ALVRLR
|. .|| | ... |... |... |. | |..|| .|.|||..|.||. .|..| || ... . ... . | ||
kkthtvkhysykGWieknaPelareilnilkv..............vrdsk.svvvhCstGiGrsaafvlaelvyqkmirsldttetveldylslleelr
RQRMLLVANFGQYRFVYSTVIH
.| . . | | .|.
skrkraihtPlqlafsilmvld
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 5-118 | 9.9e-33 | 108.9 | Pfam-A | 131-234 (235) | alignment | ||
Range on Protein: 5-118
Range on HMM: 131-234/235.0
QQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRqrtsttrssvHESKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLLV
..|.|.....|.|||| ||..|.|.|.....||. . .... ||.||| |||||||.... |... ...... ... ... .||.||. .|
ekrevkqlhytnWpdhgvpespkslldlirkveksk..........eaksgpvvVhCsaGvgRtgtfvaldilleqleaeeevdvlqivkelRkqRpgmv
ANFGQYRFVYSTVI
.. || |.| ...
qsleqYiflykail
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 5-118 | 9.9e-33 | 108.9 | In-house | 131-234 (235) | alignment | ||
Range on Protein: 5-118
Range on HMM: 131-234/235.0
QQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRqrtsttrssvHESKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLLV
..|.|.....|.|||| ||..|.|.|.....||. . .... ||.||| |||||||.... |... ...... ... ... .||.||. .|
ekrevkqlhytnWpdhgvpespkslldlirkveksk..........eaksgpvvVhCsaGvgRtgtfvaldilleqleaeeevdvlqivkelRkqRpgmv
ANFGQYRFVYSTVI
.. || |.| ...
qsleqYiflykail
|
|||||||||
subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 5-123 | 1.5e-29 | 97.8 | In-house | 150-266 (270) | alignment | ||
Range on Protein: 5-123
Range on HMM: 150-266/270.0
QQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQRTsTTRSSVHESKpPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLLV
..| . | ....|||| || .. | |. . .. ||. .... .... |.||||.|||||||..|..| .. .....|.... . . .||..|| ||
eerrlvHfwyntWpdhgvpreedsslstdqllkmlravr.rsekeldkae.PllvHcsaGvgRtGtlialDiavrlLeetkkvdvlaiieelRkdRmalv
ANFGQYRFVYSTVIHYIKN
||.|.| .|..|..
qhpeqyeflykavveyaer
|
|||||||||
subfamily_Ptp69D_pd | Subfamily Ptp69D | 5-122 | 5.3e-29 | 96.3 | In-house | 180-287 (307) | alignment | ||
Range on Protein: 5-122
Range on HMM: 180-287/307.0
QQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQRTsttrssvhesKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLLV
..| | ..| |.| ||. ... |....||..| . . |..||| |||||.|... |... ........| . ||.|| |||
dsrkvvqyhytgWkDskvPevargllklieqvrelykln..........rsPivvhCsaGvgrsgifvaldsllqqlkaedkvdifetvkdLrsqRnllv
ANFGQYRFVYSTVIHYIK
.. || |.| .. |..
qsleqYvflyralldyss
|
|||||||||
0048179 | (Phosphotyrosine protein) phosphatases II | 5-115 | 8.2e-26 | 85.8 | In-house | 45-139 (144) | alignment | ||
Range on Protein: 5-115
Range on HMM: 45-139/144.0
QQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLrqrtsttrssvHESKPPVLVHCTAGVGRTGVIILTDLMIaciqnNKRINIHHALVRLRRQRMLLV
|.........|||| |||... .||||. .|.. .|.. ||||||.|||||||.... .||. .......|| ..|..|. |
leregiqylhlpwpDhgvpdllellleflefieea...........leeggpvlVHCsaGvgRtgtlvaaylmk.....klglsleealalvrsrrpgav
ANFGQYRFVYS
|.||.||..
pnpgqlrfLle
|
|||||||||
subfamily_CG7180_pd | Subfamily CG7180 | 5-121 | 1.9e-24 | 80.8 | In-house | 178-290 (296) | alignment | ||
Range on Protein: 5-121
Range on HMM: 178-290/296.0
QQRTVYHVQFTDWPD-HRVPDDPTSFLEFLDQVESLRQRTsttrsSVHESKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLL
..|.| ..|.| |. ..|| ....|.. .|...|... .. . ||.|... |..|.|| . | . ......... .|. .|||.| |
etRivklfqlteWeledkvPlstnalielrrrvrlwrekv.....dedpeegPvvvvssdGasRsGvylaidanlelvekeeevdvFeavktlrrsRpqL
VANFGQYRFVYSTVIHYI
| | .|...| .. ...
venveeYkyiYdvlleav
|
|||||||||
subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 5-122 | 1e-23 | 78.2 | In-house | 170-277 (515) | alignment | ||
Range on Protein: 5-122
Range on HMM: 170-277/515.0
QQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESlrqrtSTTRSSvHeskpPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLLV
. ||| .||.|||. || . .|.| .. .| . .. . . | |...||.||||||||.| | ..| ... . ... . . .|..|. ||
dsrtvtqfhfteWPdkGvpkhtssllklikevka.....dhgqyt.h....pliihcsaGvGrtGvvisidsvvahakttrmvdvfnfvtnirqkrpylv
ANFGQYRFVYSTVIHYIK
|| |.| .| ...
qtqeqyafiygavledll
|
|||||||||
0051082 | (Phosphotyrosine protein) phosphatases II | 5-115 | 2.2e-22 | 74.7 | In-house | 56-147 (151) | alignment | ||
Range on Protein: 5-115
Range on HMM: 56-147/151.0
QQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESlrqrtsttrssvhESKPPVLVHCTAGVGRTGVIILTDLMIACiqnnkrINIHHALVRLRRQRMLLV
....|.|....||||. .|. . ..||||..... .. ||||||.||.||||.... .||. ... || .|..|. .|
lgievlhipildwpdpglplsfdavleflellld.............kkngpvlvHCsaGkgRTGtlvalylmllg......vsleealeeyrlkrpgvv
ANFGQYRFVYS
. |..|..
qpnqqflfqlf
|
|||||||||
subfamily_Urchin-PTP-4_pd | Subfamily Urchin-PTP-4 | 5-119 | 8.8e-19 | 62.2 | In-house | 130-234 (392) | alignment | ||
Range on Protein: 5-119
Range on HMM: 130-234/392.0
QQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESlrQRTSTTrssvHeskpPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLLV
..||| .||.|||. || .|.|.|. .|.. . . | | |...||.||||||||.| | ..| .. . ... .. .||.| .|
dartvaqfhftewPdkdvpkhtssllkfikevka..dfGqyt....h....pliihcsagvgrtgvvisidsvvahakktrmvdvfnfvtnirrkrpymv
ANFGQYRFVYSTVIH
|| |.| .|.
qtkeqyafiygavle
|
|||||||||
subfamily_Cele-PTP-8_pd | Subfamily Cele-PTP-8 | 5-121 | 3e-16 | 54.3 | In-house | 169-271 (288) | alignment | ||
Range on Protein: 5-121
Range on HMM: 169-271/288.0
QQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVeslrqrtsttrS---SvheskpPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRM
.. | .. . .|.|. ||.. |.| .|. . |..||. ||||||| .||. ... .. . . |.. | .|| .|.
ekvivkilhlleWdddgvPenylsplrllevl...........kslqk......PivvhssaGvGrtgtlililialeslrlddflgirsllaklreerf
LLVANFGQYRFVYSTVIHYI
. || .|. | ...
kaiqtemqylyvhrcvleel
|
|||||||||
subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 5-118 | 5.1e-16 | 53.6 | In-house | 134-237 (239) | alignment | ||
Range on Protein: 5-118
Range on HMM: 134-237/239.0
QQRTVYHVQFTDWPDHRVPDDPTSFLefldqveSLRQRtsTTRSSVHESKPPVlVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLLV
..| ||. .|| |||. ||. |. | ||.. |. |. ..| | .||.||||||| ... | |. ...| ..| . .| .| .|
eeryvyqyhftvwpdkgvpqyatavl.......glrrk..itkdslpgarpwv.ihcsagvgrtgaflvidamlrqakkqktvdifnyvkairedrphmv
ANFGQYRFVYSTVI
|| |.. .|.
qtseqyvfihlavl
|
|||||||||
subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 5-118 | 5.9e-16 | 53.4 | In-house | 135-238 (239) | alignment | ||
Range on Protein: 5-118
Range on HMM: 135-238/239.0
QQRTVYHVQFTDWPDHRVPDDPTSFLefldqveSLRQRtsTTRSSVHESKPPVlVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLLV
..| ||. .|| |||. ||. |. | ||.. |. |. ..| | .||.||||||| ... | |. ...| ..| . .| .| .|
eeryvyqyhftvwpdkgvpqyatavl.......glrrk..itkdslpgarpwv.ihcsagvgrtgaflvidamlrqakkqktvdifnyvkairedrphmv
ANFGQYRFVYSTVI
|| |.. .|.
qtseqyvfihlavl
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 5-119 | 7.6e-14 | 45.9 | In-house | 87-192 (440) | alignment | ||
Range on Protein: 5-119
Range on HMM: 87-192/440.0
QQRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQRTsttrssvheSKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLLV
. ||. . .. |||. || |.....|. .... .. |.||||.||.||||||| | .. . . .|.| . .| .| .|
esrtlkqyhyqgwpdkgvpkfagpvlkmiqdvnesqeka.........gngpllvhcsagagrtgviiavdsilreakrsdqidifsfinsmrnnrpqmv
ANFGQYRFVYSTVIH
|| ||. .|..
qtpeqyafvheavle
|
|||||||||
subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 6-123 | 2.7e-28 | 94.0 | In-house | 177-285 (319) | alignment | ||
Range on Protein: 6-123
Range on HMM: 177-285/319.0
QRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQRTsttrssvheSKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLLVA
|.| | |.|.|||| ||.. || |..| ... |..| .. |. ||| ||||||| | | |. .... ..... ||| || ..|
tRevkhfqyteWpdhdvPekatslldllkrirksrekt.........qsgPivvhCsaGvGRtGtfivldamlervkeegvlDvfstvsrlRtqRnimvq
NFGQYRFVYSTVIHYIKN
. ||.|.| .......
rpeqYkfiyealleavea
|
|||||||||
subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 6-118 | 6.9e-21 | 69.5 | In-house | 174-276 (315) | alignment | ||
Range on Protein: 6-118
Range on HMM: 174-276/315.0
QRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQRTSttrssvheskPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLLVA
|.|. ...| ||| || ...... .| .. . ...||| ||||||| | | .. .. .. |...... ..|..|. .|.
irevvqlhytswpdmgvpkytiplmnlirtvkqhhtnsv..........gaivvhcsaGvGrtGtfitldavldqaeaenaidvynfitgvrqnrikmvq
NFGQYRFVYSTVI
||.|.|....
vaeqyqfiydall
|
|||||||||
subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 6-121 | 3.8e-20 | 67.3 | In-house | 177-288 (325) | alignment | ||
Range on Protein: 6-121
Range on HMM: 177-288/325.0
QRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQRTST-TRSSVheskpPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLLV
|.| |. |.| |. |.... .|. |. . .| . |..| |.||||.|||||||| | ..| . .. |..| . .||..| .|
trsvkqfqlqswddmGvqkrpatlisilqlvkavservtantkast.....pilvhcsaGvGrtGvfislysalakvieesrvdifgfvkklrkdrpsmv
ANFGQYRFVYSTVIHYI
|| ..| ... ..
etvdqyiliyealveay
|
|||||||||
0049772 | (Phosphotyrosine protein) phosphatases II | 6-122 | 8.5e-20 | 67.1 | In-house | 177-281 (314) | alignment | ||
Range on Protein: 6-122
Range on HMM: 177-281/314.0
QRTVYHVQFTDWPDHRVPdDPTSFLEFLDQVESLrqRtsttrssvheSKPPVLVHCTAGVGRTGV-IILTDLMIACiqnnkRINIHHALVRLRRQRM---
.|..... ...||. .| .. |.|||. .|.. . . ||||||.||.||||. ... ||... ..... || ..|..|.
erlgikylripvpDgsap.lledfdeflefieea..d..........kggpvlvHCkaGkgRtgtfvvaaylmkll.....gvsleealedvrlkRpinp
--LLVANFGQYRFVYSTVIHYIK
.. .. || |.. . .|.|
npgfieqleqyefilealleylk
|
|||||||||
subfamily_Cele-PTP-19_pd | Subfamily Cele-PTP-19 | 6-120 | 1.9e-14 | 48.1 | In-house | 180-281 (301) | alignment | ||
Range on Protein: 6-120
Range on HMM: 180-281/301.0
QRTVYHVQFTDWPDHRVPDdptSFLEFLDQVESlrqrtsttrssVHESKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLLVA
||| | |...|.|. || | | | .| | .|. |..|||.||.||. | |. . ......|.. .|| .|| .| |
trtvthyqysewtdrgvPk...shaelfdlmel...........vkksekPivvhcsaGiGrsvafigteylareveadptieltealkhlrehrwngvq
NFGQ-YRFVYSTVIHY
. | | ||
tnsqlywmtlGtvyrl
|
|||||||||
subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 6-123 | 7.7e-12 | 39.4 | In-house | 182-285 (290) | alignment | ||
Range on Protein: 6-123
Range on HMM: 182-285/290.0
QRTVYHVQFTDWPDHRVPDdptSFLEFLDQVESLRQRTSttrssvheskpPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLLVA
. ..|.. |||. |. | | .| . .||. . || |||.||.|||| .. . . .. . | ... ||. |. |
ehklkhlkikswpdksval...stlallrtlrilrkasG...........pvvvhcsaGiGrtGtfvaievglqilldGkeldlldlvralrnsrlnsvq
NFGQYRFVYSTVIHYIKN
|| . .... |.
vdiqylalveilldlGkd
|
|||||||||
subfamily_ptpA1_pd | Subfamily ptpA1 | 6-79 | 4.3e-11 | 37.2 | In-house | 185-254 (418) | alignment | ||
Range on Protein: 6-79
Range on HMM: 185-254/418.0
QRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESlRQrtSTTRSSVhESKPPVLVHCTAGVGRTGVIILTDLMIA
| . . |. |||| .|| | ..| . || | . . |..|||.||||||| . . .|.
trditqyqyegwpdhnipdhtqpfrqllhsitn.rq..nqiipss.drnvpiivhcsagvgrtgtfctavimmk
|
|||||||||
subfamily_Nvec-PTP-3_pd | Subfamily Nvec-PTP-3 | 6-115 | 2.8e-10 | 34.7 | In-house | 93-197 (198) | alignment | ||
Range on Protein: 6-115
Range on HMM: 93-197/198.0
QRTVYHVQFTDWPDHRVPDDpTSFLEFLdqvESLRQrtsTTRSSVHESKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKR--INIHHALVRLRRQRMLL
| . | ||| | .. |. . |. |. . |. .. | ||.|||. | | |||.. |. . .. | ... |||. | .
treishyqftswkekttpnv.alfvgfv...vasre...vskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgi
VANFGQYRFVYS
.. . .| |.|
isslqhynfiyq
|
|||||||||
subfamily_Anemone-PTP-3_pd | Subfamily Anemone-PTP-3 | 6-115 | 2.9e-10 | 34.7 | In-house | 94-198 (199) | alignment | ||
Range on Protein: 6-115
Range on HMM: 94-198/199.0
QRTVYHVQFTDWPDHRVPDDpTSFLEFLdqvESLRQrtsTTRSSVHESKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKR--INIHHALVRLRRQRMLL
| . | ||| | .. |. . |. |. . |. .. | ||.|||. | | |||.. |. . .. | ... |||. | .
treishyqftswkekttpnv.alfvgfv...vasre...vskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgi
VANFGQYRFVYS
.. . .| |.|
isslqhynfiyq
|
|||||||||
PTPc_motif_SM00404 | 6-110 | 1e-08 | 30.1 | In-house | 46-133 (140) | alignment | |||
Range on Protein: 6-110
Range on HMM: 46-133/140.0
QRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVeslrqrtsttrssvHESKPPVLVHCTAGVGRTGVIILTDLMiacIQNNKRINIHHALVRLRRQRMLLVA
.... ... | . .. . |.|.... .... |||||.||| |.. .|. || ... .. .|. ||... .
gfqilqiplddnekdklskyldkvldfiena..............ekkggkvlVHCqaGvSRSatliiaYlm...ryrqlslaeayefvkerRpiispnl
NFGQY
|| .
nfvrq
|
|||||||||
subfamily_Cele-PTP-13_pd | Subfamily Cele-PTP-13 | 6-118 | 2.7e-08 | 27.8 | In-house | 166-266 (281) | alignment | ||
Range on Protein: 6-118
Range on HMM: 166-266/281.0
QRTVYHVQFTDWPDHRVPDDPTSFLEFLDQVeslRQRtsttrssvheSKPPVlVHCTAGVGRTGVIILTDLMIACIQNNKRI-NIHHALVRLRR-QRMLL
| . | . .||| .||. .|. | .. | | | ||| .||.|||||.| .. .. . |.. . .|.. . .|| |
trlithwlwkewpdwqvpessevmlkilrki...rar..........stppv.ihcsagvgrsgtlmaveialqsihshftlpdikqivshlrvtgraas
VANFGQYRFVYSTVI
| . || ... ..
vqtlqqymliwkvll
|
|||||||||
subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 7-122 | 8.3e-17 | 55.5 | In-house | 218-345 (349) | alignment | ||
Range on Protein: 7-122
Range on HMM: 218-345/349.0
RTVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQRTSTTRSSVHESKPPVLVHCTAGVGRTGVIILTDLMIA------------CIQNNKRINIHHALV
.. .|. .|.| . .| |.|. |. . | . . ...||||.|| |||||.. ||... .|. .. |. ..
yellqlqvknwldlslllnPisilqalevkndliddlfarlyldtdqlstllvhcsaGcGrtGvlvtldlllsileplqnesnkiklqallkDlisiivn
RLRRQRMLLVANFGQYRFVYSTVIHYIK
||.||. .|.|. |. ..| ....|..
elrkqrismvqnlaqfiaiyealLkyfa
|
|||||||||
PTPc_DSPc_SM00012 | 8-118 | 1e-31 | 104.6 | In-house | 1-104 (105) | alignment | |||
Range on Protein: 8-118
Range on HMM: 1-104/105.0
TVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQRTSTtrssvhesKPPVLVHCTAGVGRTGVIILTDLMIACIQNN-KRINIHHALVRLRRQRMLLVAN
||.|...|.|||| ||....|.||.|..|.. .. .. ..||.||| |||||||.... |... .... |...| . .||.||. .| .
tvkhyhytgwpdhgvPeesdsilellravkknknkses........skpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgmvqt
FGQYRFVYSTVI
. || |.| ..
eeqylflyrall
|
|||||||||
subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 8-122 | 1.7e-18 | 61.5 | In-house | 216-345 (350) | alignment | ||
Range on Protein: 8-122
Range on HMM: 216-345/350.0
TVYHVQFTDWPDHRVPDDPTSFLEFLDQVESLRQRTSTTRSSVHESKPPVLVHCTAGVGRTGVIILTDLMIA------CIQNNK---------RINIHHA
||..|. |.| . .| |.|. |. . | . . . . .|.|||| |||||||... | .. .... | |.
vvyqlqvknWkDlslllnPesilqalevkndliddlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaaktrDlisii
LVRLRRQRMLLVANFGQYRFVYSTVIHYIK
. .||.||. .| | |. |.| .. .| .
vnelrkqrismvqnldqfifiYeallfyfa
|
|||||||||
subfamily_Cele-PTP-16_pd | Subfamily Cele-PTP-16 | 8-122 | 1.1e-08 | 29.0 | In-house | 171-280 (303) | alignment | ||
Range on Protein: 8-122
Range on HMM: 171-280/303.0
TVYHV-QFTDWPDHRVPDD-PTSFLEFLDQVESLRQRTSttrssvhESKPPVLVhCTAGVGRTGVIILTDLMIACIQN-NKRINIHHALVRLRRQRMLLV
. || .. .|| .| | |. . |..|. .. | .|.|.| . .|.||.| . | . ... . ... . | .| |. |
sflhvhhykawphnsipsdgspkfvkqiwqlqsvlrkys.......dstptvym.slsgcgragtfalfetahlslhseqasldlvkclenvrngrlhav
ANFGQYRFVYSTVIHYIK
|. |. .||. . ..
qnlsqfsvvytllaehvl
|
|||||||||
0049260 | (Phosphotyrosine protein) phosphatases II | 9-114 | 4.1e-25 | 83.7 | In-house | 54-143 (152) | alignment | ||
Range on Protein: 9-114
Range on HMM: 54-143/152.0
VYHVQFTDWPDHRVPDDPTSFLEFLDQVESLrqrtS----TtrssvheskpPVLVHCTAGVGRTGVIILTDLMIaciqnnKRINIHHALVRLRRQRMLLV
...... |||| |||.. .|..|. .| | ||||||.|||||||.... .||. ..... .|. ..|..|. |
yiqylhlpwpDhgvpdlsqlllflllfiekl....aldkgg..........pvlVHCsaGvgRtgtlvaaylml......lgvsleeavalvrekRpgav
ANFGQYRFVY
|.||.||.|
pnpgqlrfly
|
|||||||||
subfamily_Cele-PTP-4_pd | Subfamily Cele-PTP-4 | 9-123 | 1.1e-13 | 45.2 | In-house | 185-287 (302) | alignment | ||
Range on Protein: 9-123
Range on HMM: 185-287/302.0
VYHVqfTDWPDHRVPDDPTSFLEFLDQVeslrqrtsttRSSVHESKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLLVANFG
||.. | |....||. .. . .| . ... .... . |.|| |... . . ..|..| ||. . .| || | ..
vyvl..tnWkqkkvpvkyaeliktaakv..........fakkikadentvivSknGaGRagafltlavaveklqkgkepnikeivksiRsqRpravdslk
QYRFVYSTVIHYIKN
|| ..| ... |||.
Qyvslyialllyikk
|
|||||||||
subfamily_Sponge-PTP5_pd | Subfamily Sponge-PTP5 | 9-118 | 2.3e-13 | 44.7 | In-house | 164-263 (283) | alignment | ||
Range on Protein: 9-118
Range on HMM: 164-263/283.0
VYHVQFTDWpdhrvpddpTSFLEfLDQVESLRQRTSTTRSSVHESKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLLVANFG
. | |. || ... | ..|| . .. | |..|||..|.|||.| | . .. . ... . .| ||| .| . .
lahyqvidW.........leyge.qaiinslvkfnkvislqteskkgPivvhCstgiGrtavfiaasasvkdaltesvvdvfavvkimreqrmmavqtld
QYRFVYSTVI
||..|. |.
qyklvhelvl
|
|||||||||
subfamily_Cele-PTP-15_pd | Subfamily Cele-PTP-15 | 9-121 | 5e-12 | 40.4 | In-house | 169-270 (285) | alignment | ||
Range on Protein: 9-121
Range on HMM: 169-270/285.0
VYHVQFTDWPDHRVPDDPTSFLEFLDQVESlrqrtsttrssVHESKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLLVANFG
. ||| |||. |.| ..|. |. | . |. |||.|||||| .. | | .| |.. . .| |. | ..
mnhvqvpwwpdqlapedarpmielykwvkk...........vnpkekpicvhcsagvgrtatfvgidyatirimenpniemldivremramrfqavqshm
QYRFVYSTVIHYI
|. |.| .. |.
qflflyvvlmeyf
|
|||||||||
subfamily_Cele-PTP-14_pd | Subfamily Cele-PTP-14 | 9-120 | 1.4e-08 | 28.6 | In-house | 192-289 (310) | alignment | ||
Range on Protein: 9-120
Range on HMM: 192-289/310.0
VYHVQFTDWPDHRVPDDptsflefldQVESLRQRTSTtrsSVheSKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLLVANFG
| ... .||| |||. .. .. || . | . |..|||.||..|..|.. .| | ... ....... |...|. . .
vslikwpnwpdrgvpde.........kchtvpqrlla...qv..rhgpcvvhcsagkdrlyvvvalklkidkldrglkvdaeevktellksraiciqtel
QYRFVYSTVIHY
|| .. | .
qyliidrvriif
|
|||||||||
0046846 | (Phosphotyrosine protein) phosphatases II | 10-123 | 1.1e-25 | 85.8 | In-house | 77-175 (176) | alignment | ||
Range on Protein: 10-123
Range on HMM: 77-175/176.0
YHVQFTDWPDHRVPDDpTSFLEFLDQVESLRQRTsttrssvheskPPVLVHCTAGVGRTGVIILTDLMIAciqnNKRINIHHALVRLRRQRM-LLVANFG
.......|||| |||. . .||.|..... ... |||||| ||.||||.... .|.. .| .....|| ..|.||. | ...
iqylhlpwpDhgvpdl.elllellefirealkeg...........gpvlVHCsaGigRtgtlvaayllel....ekglsveealalvreqRplgavqtpe
QYRFVYSTVIHYIKN
||||.| . ...|.
Qyrflyefellllkk
|
|||||||||
0044763 | (Phosphotyrosine protein) phosphatases II | 10-123 | 3.5e-24 | 80.8 | In-house | 76-173 (178) | alignment | ||
Range on Protein: 10-123
Range on HMM: 76-173/178.0
YHVQFTDWPDHRVPDDPTSFLEFLDQVESLRqrtsttrssvHESKPPVLVHCTAGVGRTGVIILTDLMIACiqnnkRINIHHALVRLRRQRMlLVANFGQ
...... .||| ||| . ||||.. .|... .|.. ||||||.|||||.|.... .||. . ......|. ..|..|. | |.||
iqylhipipDhgvpdllehflefvefieeal..........dekggpvlVHCsaGvgRsgtlvaaylmkkl.....glsleeaielvrerRp.ivpnpgq
YRFVYSTVIHYIKN
.|..| .. |.
lrqLyefelrllke
|
|||||||||
subfamily_Cele-PTP-17_pd | Subfamily Cele-PTP-17 | 13-122 | 1.8e-09 | 31.6 | In-house | 233-339 (347) | alignment | ||
Range on Protein: 13-122
Range on HMM: 233-339/347.0
QFTDWPDHRVPDDPTSFLEFldqVESLRQRTSTTRSSVHESKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLLVANFGQYRF
. | || .. ||| | . | . . .||. . | ..||.| | |. |. ..|| ..| . . | . . ..| || . . | .
ncttwpwkkypddekkvlal...vrapvkesstslianleklapvvvmcdlgldrsatvvltsiiieqvldgktpdcddlfkkmrdqragvftmsifyty
VYSTVIHYIK
. . |.|
airaalfylk
|
|||||||||
0038934 | (Phosphotyrosine protein) phosphatases II | 15-114 | 3.4e-11 | 38.6 | In-house | 85-170 (194) | alignment | ||
Range on Protein: 15-114
Range on HMM: 85-170/194.0
TDWPDHRVPDDPTSFLEFLDQVESLRQRTSttrssvhesKPPVLVHCTAGVGRTGVIILTDLMIACiqnnkRINIHHALVRLRRQRMLLVANFGQYRFVY
.||. .. . |.||| |. .. . . |.|||.||.||||... |. . ... . |. ..|. | . | .... ..
lpfpddgtvPsleillrfldlvdeflnedp.........ggvvaVHCkaGlgRtGtlvaaYLiyrl.....gmsaeeAialfrekRpgaipnqdyleall
|
|||||||||
subfamily_DSP12_pd | Subfamily DSP12 | 30-104 | 9.6e-06 | 20.1 | In-house | 65-127 (155) | alignment | ||
Range on Protein: 30-104
Range on HMM: 65-127/155.0
LEFLDQVESLRQRTS-TtrssvhesKPPVLVHCTAGVGRTGVIILTDLMiaciqNNKRINIHHALVRLRRQRMLLV
|..||.. . . . . . |||||.||| | |.. || ........|| .....
LshldeavdFieealee........egavlvHCqagvSRSvtiviAYlm.....kkeklslekAlklvkekkpeie
|
|||||||||
Y_phosphatase3 | Tyrosine phosphatase family | 40-79 | 2.1e-06 | 22.8 | Pfam-A | 110-149 (164) | alignment | ||
Range on Protein: 40-79
Range on HMM: 110-149/164.0
RQRTSTTRSSVHESKPPVLVHCTAGVGRTGVIILTDLMIA
... .. . . |.. |||.||||| ||||.. | ..
kkayrkvlealaeeegpvlfHCtaGKDRTGvvaalllsll
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 45-122 | 3.4e-18 | 60.4 | In-house | 238-316 (319) | alignment | ||
Range on Protein: 45-122
Range on HMM: 238-316/319.0
TTRSSVHESKPPVLVHCTAGVGRTGVIILTDLMIACIQNN-KRINIHHALVRLRRQRMLLVANFGQYRFVYSTVIHYIK
..||. .||. |. |||. ||||||..| .|. | .... . ..| . . .||.| | . || |.| .. | |
ssrsgtresqGPlvvhcsdGvGrtGlviasdiairsleeskrsvdiPqlvssvrrdrasavltkeqyefiykvlseyak
|
|||||||||
subfamily_DSP14_pd | Subfamily DSP14 | 47-111 | 8.3e-06 | 19.8 | In-house | 76-135 (157) | alignment | ||
Range on Protein: 47-111
Range on HMM: 76-135/157.0
RSSVHESKPPVLVHCTAGVGRTGVIILTDLMiaciqNNKRINIHHALVRLRRQRMLLVANFGQYR
.|.... .||||.||| | . | || . .......| .. .| .. | | ..
ieevkkkggktlvhCvaGvSRSAslclaylm.....kyeklsLreayklvksaRpiirPNvGFwk
|
|||||||||
subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 48-121 | 1.8e-13 | 45.1 | In-house | 186-259 (267) | alignment | ||
Range on Protein: 48-121
Range on HMM: 186-259/267.0
SSVHESKPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLLVANFGQYRFVYSTVIHYI
. . .|..|.|..||||.| . | .. .... .|.. | ..| ||. || .| ... .. .|
nqlengnrPlvvacsdGvGrsGtflvidsqleraktegvsdifdflrkirsqriglvdtkeryiyihellaeya
|
|||||||||
DSPc | Dual specificity phosphatase, catalytic domain | 48-111 | 1.1e-08 | 30.0 | Pfam-A | 67-125 (133) | alignment | ||
Range on Protein: 48-111
Range on HMM: 67-125/133.0
SSVHESKPPVLVHCTAGVGRTGVIILTDLMiaciqNNKRINIHHALVRLRRQRMLLVANFGQYR
....... |||||.||. |.. .|. || . |.... .|. ....| .. |.|. |
ekaeqkgkkvlVHCqaGisRSatliiaYlm.....ktknlslneAyefvkerrskispnagflr
|
|||||||||
DSPc | Dual specificity phosphatase, catalytic domain | 48-111 | 1.1e-08 | 30.0 | In-house | 67-125 (133) | alignment | ||
Range on Protein: 48-111
Range on HMM: 67-125/133.0
SSVHESKPPVLVHCTAGVGRTGVIILTDLMiaciqNNKRINIHHALVRLRRQRMLLVANFGQYR
....... |||||.||. |.. .|. || . |.... .|. ....| .. |.|. |
ekaeqkgkkvlVHCqaGisRSatliiaYlm.....ktknlslneAyefvkerrskispnagflr
|
|||||||||
subfamily_PTPDC1_pd | Subfamily PTPDC1 | 48-116 | 7.7e-08 | 27.0 | In-house | 110-171 (182) | alignment | ||
Range on Protein: 48-116
Range on HMM: 110-171/182.0
SSVHESkpPVLVHCTAGVGRTGVIILTDLMIAciqnnKRINIHHALVRLRRQRMLLVANFGQYRFVYST
....| | ||| || |||||.| . |. | ||.. ..|. .| .| . .| ..|
falqeg..kvavhChaGlGrtGvliacylvya.....krltaekaiklvrskrpksiqtreqvelvkef
|
|||||||||
subfamily_DSP3_pd | Subfamily DSP3 | 48-103 | 2.9e-06 | 21.0 | In-house | 91-141 (162) | alignment | ||
Range on Protein: 48-103
Range on HMM: 91-141/162.0
SSVHESKPPVLVHCTAGVGRTGVIILTDLMIAciqnnKRINIHHALVRLRRQRMLL
....... |||||..|| | ...| ||| .......|. . |..|..|
ealsqkegkvlvhcvvGvsRsatlvlayLmir.....rkmtlveairtvrkkReil
|
|||||||||
subfamily_DSP1_pd | Subfamily DSP1 | 49-108 | 5.2e-06 | 20.6 | In-house | 90-144 (163) | alignment | ||
Range on Protein: 49-108
Range on HMM: 90-144/163.0
SVHESKPPVLVHCTAGVGRTGVIILTDLMiaciqNNKRINIHHALVRLRRQRMLLVANFG
.|.... ||.|| ||. | ..| || ..||.... | ...| . |.|
evkkknGkvlihCqaGisRsstlclaylm.....ktkrvsleeafdfvkqrRsiisPnag
|
|||||||||
subfamily_DSP19_pd | Subfamily DSP19 | 51-109 | 6.4e-07 | 23.8 | In-house | 86-139 (152) | alignment | ||
Range on Protein: 51-109
Range on HMM: 86-139/152.0
HESKPPVLVHCTAGVGRTGVIILTDLMiaciqNNKRINIHHALVRLRRQRMLLVANFGQ
.... ||||| ||| |. .... || .........|| .| .| . | |
rskdgavlvHCnAGvSRsasvviaylm.....kkeelsleealelvrearpcikPneGF
|
|||||||||
PTEN_1 | 53-112 | 1.2e-08 | 30.0 | In-house | 129-184 (196) | alignment | |||
Range on Protein: 53-112
Range on HMM: 129-184/196.0
SKPPVLVHCTAGVGRTGVIILTDLMIACIqnnkrINIHHALVRLRRQRM-LLVANFGQYRF
.. |||||.||.||.|... || . . . || ..|..|. . .. | |.
ngnvVlVHCkaGlgRsGtvvaayLmykgk.....ltadeAlelvrekRppgapnspsqerl
|
|||||||||
subfamily_egg_pd | Subfamily egg | 53-122 | 8e-07 | 23.0 | In-house | 200-271 (307) | alignment | ||
Range on Protein: 53-122
Range on HMM: 200-271/307.0
SKPPVLVHCTAGVGRTGVIILTDLMIACIQ--NNKRINIHHALVRLRRQRMLLVANFGQYRFVYSTVIHYIK
||.|.. || ...... .. . . . . .| | ||..| | | .| ||| |. ...
lskpvvvqdilGvskaatlvaieiallsllrGpitkslvlravvflrlrrrlsvesvllylfvyrlvlfffr
|
|||||||||
subfamily_PTEN_pd | Subfamily PTEN | 54-114 | 6.6e-08 | 27.7 | In-house | 114-173 (184) | alignment | ||
Range on Protein: 54-114
Range on HMM: 114-173/184.0
KPPVLVHCTAGVGRTGVIILTDLMIACIQNNKRiNIHHALVRLRRQRMLLVANFGQYRFVY
| | ||| || |||||.| . |. ... .... .. . . | . | | |.|.
knvvvvHCkaGkGRtGvlivayllkslllekae.ealelfaeaRtknkkgvtiPsqrRYve
|
|||||||||
subfamily_eak_pd | Subfamily eak | 55-123 | 4e-09 | 30.3 | In-house | 234-307 (332) | alignment | ||
Range on Protein: 55-123
Range on HMM: 234-307/332.0
PP---VLVHCTAGVGRTGVIILTDLMIACIQNNKR--INIHHALVRLRRQRMLLVANFGQYRFVYSTVIHYIKN
|| .. .. | |.|| .. ||.| |.|.|. . . ... . .|. | |. |.| |..|...
ppsfapiiqsarGsaraGvfvvidllirlidnkkknlysvedlilkvkskrihsvlvalqhsfiyeivldyllr
|
|||||||||
subfamily_Sponge-PTP-7_pd | Subfamily Sponge-PTP-7 | 58-122 | 2.1e-09 | 31.6 | In-house | 2-66 (69) | alignment | ||
Range on Protein: 58-122
Range on HMM: 2-66/69.0
LVHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLLVANFGQYRFVYSTVIHYIK
.|||..| |||| .| . .| |. .| ..| . .|. | ..| | .| |.. ... .|
vvhcssgtgrtgtfiaimvemarikseklvdifnnvqymrkcrpmmvmneieyifihdalvealk
|
|||||||||
subfamily_Sponge-PTP7_pd | Subfamily Sponge-PTP7 | 59-122 | 1.5e-09 | 32.0 | In-house | 2-65 (69) | alignment | ||
Range on Protein: 59-122
Range on HMM: 2-65/69.0
VHCTAGVGRTGVIILTDLMIACIQNNKRINIHHALVRLRRQRMLLVANFGQYRFVYSTVIHYIK
|||..| |||| | . .| |. .| ..| . .|. | ..| | .| |.. ... .|
vhcssGtGrtGtfiaimvemarikseklvdifnnvqymrkcrpmmvmneneymfihdalvealk
|