Gene SYNJ in Nematostella vectensis

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family Sac
Subfamily Synaptojanin
Protein sequence
ID Type Fasta BLAST phosphatome Note
NvecP085_AA protein Get Run
NvecP085_AA_181-484 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_FIG4_pd Subfamily FIG4 30-484 1.3e-52 170.0 In-house 42-538 (569) alignment 
Range on Protein: 30-484
Range on HMM: 42-538/569.0
LLFESGAIALLSQWETEAIKKNYQKILDAYGCLGVLRINideeeTIHFLILVTGCKSVGKVLDSEIFKITSTQFVPLQVDQ-------DEEGIAEIVKLL
  |..  |  | .   || .. ..| . ||| ||..|       . ..|||||  |.|...    |.||  ....... |.       ||.   .. | .
veftkneikellasleeanrdglekkvsayGilGfvrfl.....egyylilvtkrkkvaviGghaiykiedialikitedskksekssdearylklfkdv

N-SGTFYFATGHGSQPELDLSLS----------AQQRYD------GHSPDNRFMWNRSLHFHVQRFgINCSEWLFSIMCGGVEIRTVYAGVSQAKACLIS
. . .|||.  .     |   |.          |..| |        . ...|.||  |   ..   ..  .|| .|. | |.  ..     . . .||.
dltknfyfsysydltrtlqtnlllsdsnrekekaedrvditieakkldanekfvWnnflleplkdt.vktfdWlleiihGfvsqskisvlgksiyvtlia

RLSCERAGTRFYVRGTDDDGHVANFVETEQMI-------ALDDMITSFVQTRGSVPVFWEQPGIQVG-SHKVKLSRGFEAASAAfDRHLTTQKGLYG-DV
| | . ||.||  || . .|.||| |||||..         .| ..||||.|||||..|.|   ..    ..|. .    ||||  .|.      ||  .
rrsskfaGarflkrGvnnkGdvaneveteqivheasegsldsdryssfvqlrGsvPlyWsqdasklvtkPpikidvvdPfasaa.alhfddlfqryGspi

CIVNLLGMKEGENAlSRIFQDELTESIH--------GHDTPMICFDYHRNCKGGRTSKLKDFADKARQLFNSNSLFFSKGG-KLEKRQKGVMRSNCLDCI
 |.||.  || ..   .|.. |....|.         .    | .| .|  |   .. |. ... |..  . . .|.|.   .  |.|.|..|.||.||.
iilnlvkkkekrkr.esilleefeaaieylneflPeekklkyiswdmaraskskeenvlevlekyaeksvkktGiflsapdlestkiqeGivrtnCvdcl

DRTNNMQTFIGLEMLLVQLQCLGLGSKASLVP--RFQEAFTSMWSQNGDHISRIYIGTGALDG-----K-ARVASKLRDGARSVKRTIRSNFLDGSKQEA
||||  |  ||   | .||. ||.  ...|       . .. .. . || ..  | |.   .      | |  .|| ||  ...|| .   | |  ||.|
drtnaaqfvigkvalgyqlkslGiidesklefdsdvvrlleelyedlGdtlalqygGsqlvntiktyrkiaqwssksrdiletlkryysnsfvdadkqda

IDLLL
|.|.|
inlfl
subfamily_Synaptojanin_pd Subfamily Synaptojanin 53-814 0.0 1339.9 In-house 1-753 (754) alignment 
Range on Protein: 53-814
Range on HMM: 1-753/754.0
QKILDAYGCLGVLRINIDeEETIHFLILVTGCKSVGKVLDSEIFKITSTQFVPLQVD-QDEEGIAEIVKLLNSGTFYFATGHGSQPELDLSLSAQQRYDG
|||.||||.|||||.|.. .||..||.||||||||||. |.||||||||..|.|... .||. |.|. |||.||||||.. . |. .||||||||.|.. 
qkivdaygllGvlrlnag.detlsflvlvtgcksvGkisdaeifkitstelvslrseasdedriielkkllasgtfyfsssadsasrldlslsaqrrkqe

HSPDNRFMWNRSLHFHVQRFGINCSEWLFSIMCGGVEIRTVYAGVSQAKACLISRLSCERAGTRFYVRGTDDDGHVANFVETEQMIALDDMITSFVQTRG
.| ||||.||||||.|.||||.||..||...|||.||||||||| .||||.||||||||||||||.|||..|.|.|||||||||.|.|||..|||||.||
esednrffWnrslhlhlqrfgvncddWllkvmcGsveirtvyagakqakaalisrlsceraGtrfnvrGvndeGnvanfveteqvillddkvtsfvqirG

SVPVFWEQPGIQVGSHKVKLSRGFEAASAAFDRHLTTQKGLYGDVCIVNLLGMKEGENALSRIFQDELTESIHGHDTPMICFDYHRNCKGGRTSKLKDFA
|||.||||||.|||||||||||||||..|||||||...|  ||.|.||||||.||||..||. |...|..|.| .|.|...||||...|||...||....
svPlfWeqPGlqvGshkvklsrgfeasaaafdrhleqlkeryGevvivnllGskegeevlskafkkhlkasehakdvpfvkfdyhqkvkggkkeklekll

DKARQL-FNSNSLFFSKGGKLEKRQKGVMRSNCLDCIDRTNNMQTFIGLEMLLVQLQCLGLGSKASLVPRFQEAFTSMWSQNGDHISRIYIGTGALDGKA
.|. .| ..|.|.|.|||...||.|.||.|.|||||.||||..||..|||.|  ||..|.|.||.|.| ||.|.|.|.||.|||.||.||.|||||.|||
kkqlklflesasfflskgkevekeqtGvlrvnClDCldrtnavqtvlglevlekqlealklsskesvvsrfeevfkslWsknGdeiskiyaGtgalegka

RvASKLRDGARSVKRTIRSNFLDGSKQEAIDLLLLGNTFVGELGERARALLYSSFLHSSPRILRELCDRHLEYTTWSNIRVCVGTWNVNGGRHFRSLAHK
. .|||.||||||.|||..||||.||||||||||||||.|.||...|||||.||.|..|..||.||..|. |.|.....|.||||||||||...||.|.|
k.vsklkdgarsvartiqnnfldsskqeaidllllgntyveeladkarallkssllrasakilkelvereqelteakklricvgtwnvnggkqlrsvalk

HQTMHDWLLDfhkslpdsgYSEVKDVDYSLPTDIFAIGFEELVDLNASNMVSTSSTQRKEWGEELRRVISRDFPYVLLTCEQLVGVCLFVFARPHLVPYI
.....|||||          .|.. ...| |.||.||||||||||||||.||.|.|.||||.|||..|.|||..|||||.|||||||||||.||.|||.|
nesltdwlld.........lpelsgaedskpadiyaiGfeelvdlnasnlvsasttnrkewaeelqkvlsrdakyvlltseqlvGvclfvfvrpklvpfi

RDVAVSTVKTGLGGSAGNKGGVAIRLLLHATSICFICSHLAAGQSGVQDRNNDYLDIATRTAFPMGRTIRSHDYVFWCGDFNYRIDMPMDEVKSLIQLKD
||||||||||||||.|||||.||||||||.||.|||||||||||| |..||.|| .||...|||||||..|||||||.||||||||...||||.|.. ||
rdvavstvktGlgGaaGnkGavairlllhstslCfiCshlaagqskvkernedyaeiarkiafpmgrtleshdyvfWlGdfnyridlekdevkelvkkkd

WDALAQNDQLNKQRQEHKVFRGYVEGELRFAPTYKYDLFSDDYDTSEKMRIPAWTDRVLWRRRK
.|.|..||||.||....|||.|..||||.|||||||||||||||||||.|.|||||||||||.|
ydklvendqltkqkkkgkvfkgfaegeltfaPtykydlfsddydtseklrvPaWtdrvlwrrkk
Sac_COG5329 53-869 7.7e-123 402.7 In-house 53-876 (1070) alignment 
Range on Protein: 53-869
Range on HMM: 53-876/1070.0
QKI---LDAYGCLGVLrinidEEETIHFLILVTGCKSV-GKVLDSEIFKITSTQFVPLQVD-QDEEGI----AEIVK------------LLNSGTFYFAT
...      ||.||..     | |   |||..|| ..| . .   .|.||   .|..|. .  |.| |    |.. |            ||  |.||| |
rslssaheiygvlGli.....elegslflivitgkskvaqvipgetiykilavdfislnnnkwddeeiesdeasteklrsehpcselkkLlsngsFYfSt

GHGSQPELDLSLSAQQRYDGHSPDNRFMWNRSLHF----HVQRFGINCS------EWLFSIMCGGVEIRTVYAGVSQAKACLISRLSCERAGTRFYVRGT
      .|  .|. .. .   . |..||||. |      . ..   . .      ..|  . .| .|   .. .  ..   ||||.| .||||||  || 
dfditntLqkrlkeelelsvdtadeefmwnsflleelinyrsklsslekqlldnagFlttvIrGFaetvfikvkkktiaLtlISRrSskragtRflarGv

DDDGHVANFVETEQMIALDDMITSFVQTRGSVPVFWEQPGIQVGSHKVKLSRGFEAASAAFDRHLTTQKGLYGDVCIVNLLGMKEGENALSRIFQDELTE
||||.||||||||| .   . ..||.|.|||.|.|||| . .  . |.. .| .||. .|||.| . .   |||| |||||. |. |  ||. .. .|..
DddGnvanFVETEqIvyssqycfsFtQvRGSiPiFWeqesnsligpkiqitrsseatqsafdkHFdklfekYGdvhivNLlktKssEieLseryekhlkl

SiHGHDTPMICFDYHRNCKGGRTSKLKDFADKARQLfNSNSLFFS---KGGKLEKRQKGVMRSNCLDCIDRTNNMQTFIGLEMLLVQLQCLGLGSKASLV
|    ..  . ||.|. ..  . ...| . ....|   ... .||   | ||| ..|.||.|.|||||.||||  |. |....|| |.. ..  |. .  
s.ekpkihlteFdfhketsqdgfddvkkLlplieqd.llefgyfsydvkegkliseQdGVfRtNClDCLDRTNviQqliskrvlleqfrsikvisaidde

pRFQEAFTSMWSQNGDHISRIYIGTGALD------GKARVASKLRDGARSVKRTIRSNFLDGSKQEAIDLLLlgntfvGELGERARALLYSSFLHSSPRI
  | .... .|. ||| ||.|| |||||       ||  .|..|.|   ||.| .  || |..||.||||||      |.| ..    || .     .  
.dflqklneLWadnGDaisqiYTGtgalkssftrkgkrsiagalsDatkSvsRmyinnfvDkekQdaidllL......gklpdqeavelydpineyvnlr

LRElcdRHLEYTTWSNIRVCVGTWNVNGGRHfrslahkHQTMHDWLLDFHKslpdsgysEVKDVDYSLPTDIFAIGFEELVDLNASNMVSTSSTQRKEWG
||.   .  |.|. .|. . ..| |.||  .        .   ..||.. .        ....  . ..  .. .   ||..|. ..  .....  .   
lrk...seseftaaknvsiftltfnsngess.......stkllklllkvle........kkisklvvgvvglqkqiwlelillssltksefkeeeeenlv

EELRRVIsrDFPYVLLTCEQLVGVCLFVFARPHLVPYIRDVAVSTVKTGLGGSAGNKGGVAIRLLLHATSICFICSHLAAGQSGVQDRNNDYLDIATRTA
... .    .. ...   .|| .. .... .     .   . . . ||| || ..||| |.|. .  .....|  ...|...  ...||..|  |  |  
rkyenkl..kkkkleqsssqltalfilfkksadikevvssekaagrktgtgglnankgavkieaeseglvfifvdasaaledenesernskyesitkrvs

FPMGRTIRSHDYVFWCGDFNYRIDMPMDEVKSLIQLKDwDALAQNDQLNKQRQEHKVFrGYVEGELRFAPTYKYDLFSDDYDTSEKMRIPAWTDRVLWRR
....  |  |.  .. ...|..||.. .||.   . .. | ...... ... .| ... . |. .  . ......   ||.||... . .....|.| ..
keipkmikdhqlilldiainltidydeeevraekekei.drelkkydtkqeltekvfv.ekvleptevpellekksyeddndtdtedayrklrtrkliqk

RKP--RYKSAD-HVKKHVIKKNERNVSENLLLGDEIVNDDAEEEEEDEDDDDDEQESTTE
 .   .. . .  .| .  |   ..|. . |  || ...  |.... .    ...| ..|
eekktelaysslelkisdhkpvtaevkiavlskdekkklklelslkiayktekpselpee
subfamily_SAC1_pd Subfamily SAC1 57-489 6.2e-91 296.3 In-house 6-454 (458) alignment 
Range on Protein: 57-489
Range on HMM: 6-454/458.0
DAYGCLGVLRINideeeTIHFLILVTGCKSVGKVLDSEIFKITSTQFVPLQVDQD----------EEGIAEIVKLLNSGTFYFATGHGSQPELDLSLS--
. .|.||....      . ..||..|  ..||..  . |.... .. .|..  .           .| .. . ..|.| ||||.. .     |.   .  
kiagilGiikLl.....sgkylivitkkeevgringkviyrvadveiipvkknslslteeqkkeekeylkllelvlksetfYfsytydltnslqrlekvt

---AQQRYDGHSPDNRFMWNRSLHFHVQRfGINCSEWLFSIMCGGVEIRTVYAGVSQAKACLISRLSCERAGTRFYVRGTDDDGHVANFVETEQMIALDD
    ..|   .  |.||.||. |  ....   . ....  .. | ..|...    .. |  |||| |. |||||..||| | .|.|||||||||.. .. 
saalkerslleradeRffwnkhlledlrk.epelesfilPvikGfikikelslnakeikfilisRRsifRaGtRyfvRGvdkeGnvanfvEtEqiveaek

MITSFVQTRGSVPVFWEQPGIQVGSHKVKLSrGFEAASAAFDRHLTTQKGLYGDVCIVNLLGMKEGENALSRIFQDeLTESIHGHDTPMICFDYHRNCKG
 .|||||.|||.|..|.| .      |||||   |  ..||..|| .|. |||.  .|||.  |  |. |   ... .... . ...  . ||.|..|. 
altsFvqvRGsiPllWsqkpnLkykPkvkls.esedsldafkkhldeqielygenvlvnLvdqkGsEkklgeayes.vvralnkkkikyvafDFHkeCrk

GRTSKLKDFADKARQLFNSNSLFFS-KGGKLEKRQKGVMRSNCLDCIDRTNNMQTFIGLEMLLVQLQCLGL---GSKASLVPRFQEAFTSMWSQNGDHIS
 |  .||   |. ..  .. ..|.  . .|. |.||||.|.||.||.|||| .|. .. |.|  ||. ||.   .|| .  ......|  .|..|.|..|
mrwdrlklLidqlekelsqegyflkseekkivkeqkgvvRtnCiDcLDRtnvvqsllarevLqkqleslgvlateskledsaeletsfknlwadnadavs

RIYIGTGAL------DGKARVASKLRDGARSVKRTIRSNFLDGSKQEAIDLLlLGNTF
  | |||||       ||  .   ||||  ||.| .. ||||| .|..|||. ||.. 
vqYaGtgAlKtDftRtGkrtllGalrDgvnsvsryyknnfldgerqdsidLf.lgkyr
Syja_N SacI homology domain 58-344 6.2e-77 249.9 Pfam-A 1-317 (319) alignment 
Range on Protein: 58-344
Range on HMM: 1-317/319.0
AYGCLGVLRINIdeeetIHFLILVTGCKSVGKVL-DSEIFKITSTQFVPLQVDQDE----------------EGIAEIVKLLNSGTFYFATghgsqpELD
|||.||..|..       ..|...|....|.|.  . .|.||.|..|.||. ...|                . .... |||.||.|||..      . |
aygilGlirlls.....esyllvitkrekvakirgehpiykiksvefiplnseeeessaieeekeeeekeeekllkllkkllssgsfYfSy......dyD

LSLSAQQRYDGH---------------SPDNRFMWNRSLHFHVQRFGINCSEWLFSIMCGGVEIRTVYAG-VSQAKACLISRLSCERAGTRFYVRGTDDD
|. |.|...  .               ..|.||.||| |. .........|.||. ...| ||.|...    .... .|||| |..|||||.  ||.|||
ltrslqrksekeeeekeeeskslpllkevderFvWNrnllkplielkldlsrwllpliqGfveqrsievkskkkveltLIsRrsvkraGtRylrRGiddd

GHVANFVETEQMIA-L-D--DMITSFVQTRGSVPVFWEQ-PGIQvGSHKVKLSRGFEAASAAFDRHLTTQKGLYGDVCIVNLLGMKEGENALSRIFQDEL
|.|||||||||..    .  . ..||||.|||||.|||| ....  ..|.|..|  ||...||..|.....  ||....||||. |..|..||. .....
GnvANfvEtEqivsekkeeskrvfSfvqiRGSvPlfWeqasnls.lkpkikitrsseasqkafkkHfkklikrYgkivvvnLlekkgrEkkLseayeeli

TES----IHGHDTPMICFDYHRNCKGGRT
..      . ..  .| ||.|..||| ..
nklnkklkekkklkyiefDfhkeckgkkf
Syja_N SacI homology domain 58-344 6.2e-77 249.9 In-house 1-317 (319) alignment 
Range on Protein: 58-344
Range on HMM: 1-317/319.0
AYGCLGVLRINIdeeetIHFLILVTGCKSVGKVL-DSEIFKITSTQFVPLQVDQDE----------------EGIAEIVKLLNSGTFYFATghgsqpELD
|||.||..|..       ..|...|....|.|.  . .|.||.|..|.||. ...|                . .... |||.||.|||..      . |
aygilGlirlls.....esyllvitkrekvakirgehpiykiksvefiplnseeeessaieeekeeeekeeekllkllkkllssgsfYfSy......dyD

LSLSAQQRYDGH---------------SPDNRFMWNRSLHFHVQRFGINCSEWLFSIMCGGVEIRTVYAG-VSQAKACLISRLSCERAGTRFYVRGTDDD
|. |.|...  .               ..|.||.||| |. .........|.||. ...| ||.|...    .... .|||| |..|||||.  ||.|||
ltrslqrksekeeeekeeeskslpllkevderFvWNrnllkplielkldlsrwllpliqGfveqrsievkskkkveltLIsRrsvkraGtRylrRGiddd

GHVANFVETEQMIA-L-D--DMITSFVQTRGSVPVFWEQ-PGIQvGSHKVKLSRGFEAASAAFDRHLTTQKGLYGDVCIVNLLGMKEGENALSRIFQDEL
|.|||||||||..    .  . ..||||.|||||.|||| ....  ..|.|..|  ||...||..|.....  ||....||||. |..|..||. .....
GnvANfvEtEqivsekkeeskrvfSfvqiRGSvPlfWeqasnls.lkpkikitrsseasqkafkkHfkklikrYgkivvvnLlekkgrEkkLseayeeli

TES----IHGHDTPMICFDYHRNCKGGRT
..      . ..  .| ||.|..||| ..
nklnkklkekkklkyiefDfhkeckgkkf
subfamily_INPP5F_pd Subfamily INPP5F 115-813 4.4e-177 582.0 In-house 126-804 (951) alignment 
Range on Protein: 115-813
Range on HMM: 126-804/951.0
IAEIVKLLNSGTFYFATghgsqpELDLSLSAQQRYDGHSPD------NRFMWNRSLHFHVQRFGINC-SEWLFSIMCGGVEIRTVYAGVSQAKACLISRL
. |. |||..|.||. .      . ||. . |.|   .  .      .||.||. |   .     .  .|.|. .. | ||.....    ...  |||| 
leelkkllsdgsFYysl......dfDltntlqkrgleeksestddwderFfWNkfllkdlinyrdkldkefltpviqGfvetkeisieklkvsltlisrr

SCERAGTRFYVRGTDDDGHVANFVETEQMIALDDMITSFVQTRGSVPVFWEQPGIQVgSHKVKLSRGFEAASAAFDRHLTTQKGLYGDVCIVNLLGMKEG
| .||||||. || ||||.||||||||...   . . ||.| ||||||||||.| .. . |.|. | .|.. .|||.|.. |   || |.|||||  |. 
SrkragtrfkrrGidddgnvAnfvEtElilsvekyvlsftqirGSvPvfweqsgkky.kpkikitrseeetqpaFdehfkeqlkkygkvvivnllsqkss

ENALSRIFQDELTESIhGHDTPMICFDYHRNCKGGRTSKLKDFADKARQLFNSNSLFFS-KGGKLEKRQKGVMRSNCLDCIDRTNNMQTFIGLEMLLVQL
|  ||. ....|...   .|. .| ||.|....| ......   .. ..   .   |.  . .|.  .||||.| |||||.|||| .|. |....|  ||
ekklskaykeqllkle.skdvflikfdfheetsgekfenvsklielikneikevgyfsydvkekviseqkgvfRtnclDcldrtNvvqqaiskavlelql

QCLGLGSKASLVP--RFQEAFTSMWSQNGDHISRIYIGTGALDG------KARVASKLRDGARSVKRTIRSNFLDGSKQEAIDLlllgntFVGELGERAR
. ||| .  | ..  ......  .|..||| |||.| || || |      . ..|  | ||  ||.|   .|| |  .|..|||        |.| .   
eklglfepessiddeellqklkklWadngdaisrqYagtnalkgdltrkgerklaGvlkdgyksvsryylnnfkdkyrqkvidl......llGklpkqev

ALLYSSFLHSSPRILrelCDRHLEYTTWSNIRVCVGTWNVNGGRHFrslahkhQTMHDWLldfhkslPDSGysevkDvdySLPTDIFAIGFEELVDLNAS
. |.    ..    |     .. ..|..||| . ||. ||||  ..       . .  .|       .. |     .      .|.. .| .| |.| | 
velidpkkeekeeel...rekeekftetsninllvgsvnvngsskk.......adlskll.......fpig.....e...kfkpDlvvlGLqEvvELtaG

NMVSTSSTQRKEWGEELRRVI---SRDFPYVLLTCEQLVGVCLFVFARPHLVPYIRDVAVSTVKTGLGGSAGNKGGVAIRLLLHATSICFICSHLAAGQS
..... .. .| | . . ...   ||.  |..|  |||... | .|.|   . ....| ..|.|||.|| |||||.||.|.   ||| ||. ||||||.|
siLaaDyskskfWEklvedlLnkvsreekYlkLrseqlsslLlllfvredkakkvkevegdtkktGfgGlagnkGavavrfeysatsFcfvnsHlaAGas

GVQDRNNDYLDIATRTAFPMGRTIRSHDYVFWCGDFNYRIDMPMDEVKSLIQLKDWDALAQNDQLNKQRQEHKVFRGYVEGELRFAPTYKYDLFSDDYDT
 |..| .|| .||   .|. ...|. ||..|| ||.|||||.| .||.  .  ...| | . |||.|. .. .|| |. |  |.| ||||||| ...|||
nveeRrsDykeiarsitFsrskrikdhDsifWlGDlnyRidlpneevRRelldqeidkLleyDqLtkeieaGevFegfkEetlkFrPtYkyDlgtknYDt

SEKMRIPAWTDRVLWRRR
|||.|.||||||.... .
sekeRtPaWtDRiiykge
Exo_endo_phos Endonuclease/Exonuclease/phosphatase family 534-816 4.5e-28 88.7 Pfam-A 1-227 (249) alignment 
Range on Protein: 534-816
Range on HMM: 1-227/249.0
GTWNVNG--GRHFRslAHKHQTMHDWLLDFHkslpdsgysevkdvdyslpTDIFAigFEELVDLNASNMVStssTQRKEWGEELRRVISRDFPY--Vllt
.||||.|   |. |  | |.. . |.| . .                    |. .  . | .. . |..     |. .... . .   |. ...      
ltwNvlgwnarsdr..akkldqladllqsed...................pDvll..LQEvdedplsella...tglaselgldgdgksggggggda...

ceqlVGVCLFVFARPHLVPYIRDVAVSTVKTGLG---GSAGNKGGVAIRLLlhATSICFICSHLAAGQSGVQ--DRnNDYLDIATRTAFPMGRtirshdY
    .| .| ....  |. .||.. ....|.| .   .| ||||.|..|.    ........||..|..  |   |  .. .|. . ... |.      .
....gggglallskypldkkirrtfqldgkagiavprlssgnkgdvpvrfr..gktlalvntHltpgnrlrqrder.allaeidkladdsrgs......p

VFWCGDFNYRIDMPMdevksliqlkdwdalaqndqlnkqrqehkvfRGYVEGELRFAPTYKYDLFSDDY-------------DTSEKMRIPAWTDRVLWr
|...||||.|.| |                                .|. |..  |.|....| .....             ||.|| |.||..|..|. 
vilaGDfNsrpdspd...............................kgfresaadflpgdgfddglrallphlllptspgttdtyekareparlDyilv.

rrkpR
    .
....s
DUF1866 Domain of unknown function (DUF1866) 906-1025 1.8e-25 78.3 Pfam-A 1-124 (146) alignment 
Range on Protein: 906-1025
Range on HMM: 1-124/146.0
EVEIQKVDWEHQHQIHDHVMQSMGPADPTVVVSSDQ-TGDGDEGID---VSELLEVLEPCGDAVLVRVVDEEIIVTFDDGRSALKALELDGKKISGKTAK
.|||..|| |...... .|..  || | |.||| .. . |..|  |   ..|||. |   |. .||| |.....||| ||.|||..|.|.|.|. |.. |
dveilevdpearravfkeviaaqGPpDativvslksgdedekeifdealieeLlqelaslGeviLvRfvedkmlvtFrdgesALevlslkgikvlgralk

IRLKCDSSLSKTDLTLQSVTSNTS
|||| .  |.. .  .   |..| 
irlKskdWlksleeEivlstteti
RRM_6 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) 948-999 5.8e-06 12.8 Pfam-A 9-68 (70) alignment 
Range on Protein: 948-999
Range on HMM: 9-68/70.0
GIDVSELLEVLEPCGDAVLVRVVDE-------EIIVTFDDGRSALKALELDG-KKISGKT
 .....|.| .||.|.   ||.. .       . .|.|..  .| |||.  . ... |.|
svteedlreffepygkvegvriprnkdgrgrgfAfVefespeeAqkalkklnglvlkgrt
RRM_1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 950-999 9.3e-07 16.5 Pfam-A 11-68 (70) alignment 
Range on Protein: 950-999
Range on HMM: 11-68/70.0
DVSELLEVLEPCGDAVLVRVVD-------EEIIVTFDDGRSALKALE-LDGKKISGKT
. .|| |.....|. . ...|           .|.|.. ..| |||| |.|||. |..
teeeLkelFskfGpiesiklvrdetgrskgfafVeFeseedaekAlealngkklggre
PBD P21-Rho-binding domain 1252-1296 2e-08 21.1 Pfam-A 1-47 (59) alignment 
Range on Protein: 1252-1296
Range on HMM: 1-47/59.0
QIGMPFNVQHIGHVSIDNFQALL-EAAKDDPKLLPSF-MTSDAQKTE
.|. |....|. || .|..   .    .   |||.|  .....|| .
eIStPtdfkHvaHVGfdgqsgfftglppewekllkssgisekeqkkd