MINPP1-2, Gene Page

Gene MINPP1-2 in Nematostella vectensis

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level	Class	Gene list	Wiki page
Fold	HP
Superfamily	HP
Family	HP2
Subfamily	MINPP1

Protein sequence

ID	Type	Fasta	BLAST phosphatome	Note
NvecP133_AA	protein	Get	Run
NvecP133_AA_0-250	phosphatase_domain	Get	Run

Domains

Summary

Details

Domain	Domain Description	Range	Significance	Score	Source	Profile Range (length)	Alignment
0049226	Phosphoglycerate mutase-like	1-244	1e-37	123.2	In-house	115-340 (342)	alignment
Range on Protein: 1-244 Range on HMM: 115-340/342.0 PKDHDKVLRP-YSMCPRYDQVVDGRNGMLEPRKFAqgSEMQRVISNVKSRLGMPKNaeLNVEVVEKMFMLCAFLTVND-NDTSWCSLFEEEDLNVLeYYL \|...\| .\|.. \|..\|\|..\|.... . \| .\| .\|.. ........\|\|.. . ..\|.. .. \|... .... . .\|\|\|\|\| \|.\|..\| \|.\| pesndtllllpydscpnfdkllkellkseevqlfl..eeildllkklskllglnls..tlsdvadtlydlllyelahglplppwcslftleelkal.yal DMWQYYEHGYGHEITYKSICPLVAEIAQTIKSFTK-KKIPNGIFRFAHSGGIISLQSILSLYRDPIPltagnyhklsnrtfriarnaPMSSNIAFVLHEC \|...\|\| \|\|\|.\|\|.. ...\|\|. \|\| . ...... .. . .. \|\|\| . \|..\| \|.\| \|. \| .\| \|..\|\|..\| \|.\|\| dllyyygigygeeiarlaggpllneilarleeaiegpsdlklylyfahdttiaallsalglfddqlP....................pyasnlvfElyec TDGYKVQVLVNERL------TVLPCCkSAVCKLDKFLECYEAIGSNcDLEKMC ...\| \|.\|\|.\|.. \|\| \| . \|.\|\|.\|.\|... . . \| \|..\| dgeyyVrvlynggvlslpvtlplpgc.dglcpldefkelvkkflpg.dfeelC
0053031	Phosphoglycerate mutase-like	1-244	1.4e-34	113.0	In-house	115-340 (342)	alignment
Range on Protein: 1-244 Range on HMM: 115-340/342.0 PKDHDKVLRP-YSMCPRYDQVVDGRNGMLEPRKFAQgsEMQRVISNVKSRLGMPKNAELNVeVVEKMFMLCAFLTVNDNDTSWCSLFEEEDLNVLeYYLD \|...\| .\|.\| \|..\|\|..\|...... . \| .. . ... ... . ..\|\|.. . \|.. \| . . .\|.. \|... .\|\|.\|\| \|.\| .\| \|.\|\| pessdalllpnydpcpafdkllkealaseevkelle..rylellqklskglgltlsdlldl.vsdlydlllyelahglplppwctlftleelkal.yald MWQYYEHGYGHEITYKSICPLVAEIAQTIKSFTKK-KIPNGIFRFAHSGGIISLQSILSLYRDPIPltagnyhklsnrtfriarnaPMSSNIAFVLHECT ...\|\| \|.\|.\|... ...\|\|. \|\| . ....... . . .. \|\|\| . \|..\| \|.\| \|. \| .\| \|..\|\|..\| \|.\|.. llyyyglgpgnelaklaggpllneilarleekisgpldlklylyfahdttiaallsaLglfddqlP....................pyasnlvfElyedp DGYKVQVLVNER------LTVLPCCKSaVCKLDKFLECYEAIGSNcDLEKMC ..\| \|.\|\|.\|.. \|\| \| . \|.\|..\|.\|... . . \| \|\|.\| geyyVrvlynggtlseplvlplpgcdg.lcplsefkelvkkllpg.dfeklC
subfamily_MINPP1_pd	Subfamily MINPP1	2-247	1.8e-91	299.1	In-house	166-417 (420)	alignment
Range on Protein: 2-247 Range on HMM: 166-417/420.0 KDHDKVLRPYSMCPRYDQVVDGRNGMLEPR-KFAQGSEMQRVISNVKSRL-GMPKNAELNVEVVEKMFMLCAF-LTVNDNDTSWCSLFEEEDLNVLEYYL ...\|\|.\|\|....\|..\|.. \|. .. .\|. . .\|....\|.\|........\|\| .. \|..\|\|. ...\|.\|\|..\|\|. \|........\|\|\|\|\|\|...\|..\|\|\|. qesdklLrffdsCkkyknkvkknelnlkeeeefleskelqkaleeiakrlneekklleltekdiedmfeiCayelaikgisnvWcslfekdelleleYle DMWQYYEHGYGHEITYKSICPLVAEIAQTIKSFTKKKIPNGIFRFAHSGGIISLQSILSLYRDPIPLTAGNYHKLSNRTFRIARNAPMSSNIAFVLHEC- \|...\|\|..\|\|\|.\|\|.\|.. \|\|\|...\| ...\|\|....\| .. .\|\|\|\|......\|.\|.\|.\|\|.\| ..\|\|\| \|\|\|\|\|\|\|\|.\|\| .. .\|...\|.\|\|\|\|..\| dLknyykegyGyeinysiscpLlndivkllksseeqkqkssslrFaHaetllpllsllGlykDeekLtannyhklsnrkfrssvivpyaanlafvlydCs TDGYKVQVLVNERLTVLPCCKSAV--CKLDKFLECYEAIGSNCDLEKMCKLD .\|.\|\|\|.\|\|.\|\|... \|..\|.... \|.\|..\|.\|.\|..\| .\|\|\|\|\|\|.\|... kdqykvlvllnekvvkletcsegeifCelqdfkeiykkivdncdleklCevs
0048946	Phosphoglycerate mutase-like	2-250	5.8e-47	153.6	In-house	174-415 (447)	alignment
Range on Protein: 2-250 Range on HMM: 174-415/447.0 KDHDKVLRPysMCPRYDQVVDGRNGmlEPRKFaqgsEMQRVISNVKSRLGmpkNAELNVEVVEKMFMLCAFLTVNDNDTSWCSLFEEEDLNVLEYYLDMW ...\| .\|.\| .\|\|...... . \| \|. ...... .\|. \|\| . .\|... \| .. \|... \|. . . .\|\|\|\| .\|.\|.\|\|\|\|. \|.. ssndnlllp..sCpafkellkkela..eelke....llkellerlkkllg...glnltlsdvydlydlllyetaihglsplcslftpeelevleyladle QYYEHGYGHEITYKSICPLVAEIAQTIKSFTKKKIpNGIFRFAHSGGIISLQSILSLYRDPIPLTAGNYHKlsNRTFRIARNAPMSSNIAFVLHEC---- .\|\|\|.\|\|\|.\|... . .\|\|. \|\| . ... .... .. \|\|\| . \|..\| \|.\| \|. \| .\|\|.\|.\|. . \|\|.\|\|. . \|..\|\|..\| \|.\|\| fyyeygygdelarlaggpllneilarledaisgds.klylyfaHdttiaallsaLglfddelplpadnlpf..nrlfrsseivPyasnlvfElyecpssl --TDGYKVQVLVNERLTVLPCCKSA---VCKLDKFLECYEAIgSNcDLEKMCKLDLPN ...\| \|.\|\|.\|.. \|\|.\|.\| \|.\|\|.\|.\|... . . \| \|\|.\|.\|.\|.. psdgeyyVrvlyngeplplpgCgsgpgglCplddFkellkkf.lp.dweklCgltlsv
0047369	Phosphoglycerate mutase-like	2-245	1.5e-41	136.0	In-house	172-437 (438)	alignment
Range on Protein: 2-245 Range on HMM: 172-437/438.0 KDHDKVLR--PYSMCPRYDQVVDGRNGMLEPRKFAqgseMQRVISNVKSRLGMpknAELNVEVVEKMFMLCAFLTVNDND-----TSWCSLFEEEDLNVL ...\| .\|. \|...\|\|..\|...... . \| .. ...... .\|. \|. .\|... \| .. \|\|\|. \|.. .. ..\|\|\|\| .\|.\|.\|\| esddfllnllpsdscpafdellkeflasdeflell....lkdilkrlkkllpg...lnltpsdvldlydlcaydtlangyaglplspfcslftpeelevl EYYLDMWQYYEHGYGHEITYKSICPLVAEIAQTIKSFTKKK-----------------IPNGIFRFAHSGGIISLQSILSLYRDPIPLTAGNYHK-LSNR \|\|. \|...\|\|..\|\|\|.\|... ...\|\|. \|\| . ... ..\| . .. \|\|\| . \|..\| \|.\| \|. \| .\|\|. .. \| \|\| eyladlefyylygygnelaklaggpllneilarledaingkstnlnltldsngvtfPldlklylyfaHdttiaallsaLglfddtwplpglpldkialnr TFRIARNAPMSSNIAFVLHECT--DGYKVQVLVNERLTVLPCCKSA---VCKLDKFLECYEAIGSNcDLEKMCK .\|\|. . .\|..\|\|..\| \|.\|\|. ..\| \|.\|\|.\|.. \|\|.\|.\| \|.\|\|.\|.\|... . . \| \|..\|. lfrsseivPyasnlvfElyecpsdgeyyVrvlyngkvlplpgcgsgpgglCplddFkelvkkllpg.dfeelCg
subfamily_ACP2_pd	Subfamily ACP2	2-246	1.5e-08	26.6	In-house	125-358 (361)	alignment
Range on Protein: 2-246 Range on HMM: 125-358/361.0 KDHDKVLRPYSMCPRYDQVVDGRNGMlePRKFAQGSEMQRVISNVKSRLGMPKNAELNVEvVEKmFMLCAFLTVNDndTSWCSLFEEEDLNVLEYYLDMW ...\|..\|\|. . \|\|\|\|\|.... . \| . .\| . ........ \| . . \| .. . . ..\| . \|. .. .....\| .. \|\| . \|. eeedlllrakknCprydellqeakes..pevkklleenkelleklsestgedidlenfyq.lsd.tlicerkyane..lnlpewandelfekleeladkv QYYEH----GYGHEITYKSICPLVAEIAQTIKSFTK---KKIPNGIFRF-AHSGGIISLQSILSLYRDPIPLTAgnyhklSNRTFRIARNAPMSSNIAFV . .\| . \|. .. \|\|..\|. . .\|. .\| \|\| . .\| . \|\| . .\| ..\|..... .\| .\| \| . . .. . .. .. keaefglnnektrelkklrgGpllnellenmkeklkceekkkklklflYSaHDttlaalLeaLgifekkappya......saiivElyeeddgkplvkvl LHECTDGYKVqvlvneRLTVlPCCK-SAVCKLDKFLECYEAIGSNCdLEKMCKL .. \|. . .\|\|. \| \|\| .. \|.\|.\|\| .... . . ....\|. yrnetskdpp......eltl.pgCkgeedCplskfkkivkpfipdd.vdelCea
His_Phos_2	Histidine phosphatase superfamily (branch 2)	3-208	1.5e-14	46.6	Pfam-A	149-347 (347)	alignment
Range on Protein: 3-208 Range on HMM: 149-347/347.0 DHDKVLRPYSMCPRYDQ-VVDGRNGMLEPRKFaQGSEMQRVIS-NVKSRlgMPKN-AELNVEVVEKMFmLCAFLTVNDNDTSWCSLFEE--EDLNVLEYY ... .. .. \|\|.... .. . . \| .. ..\|. .. ... .... ..\| \|. \|\|.\| ..\| ... . . ...\|... .\|. .... lkellregaescpafawppikvekrvvelvnk.lkkvmdenlakrlsal..ctgednllfkerweklf.reffeeekfdiskipelydtmkydalhnrql LDMWQYYEH-GYGHEITYKSICPLVAEIAQTIKSFTKKKI----PNGIFRFAHSGGIISLQSILSLYRDPIPLtagnyhklsnrtfrIARNAPMSSNIAF \|. ..\| \|.\|.\|. \| .\|. .... \|.\| .... .. \|.\| \|..\| ..\| \|. . .. ... \|..\|.\| \| edleelyklygigdeeklkigllllnpllkkilsdleetqpsrhaklrlyfthDshiytllnaLgleekiare..............aspelpyasqivf VLHECTDG-YKVQVLVN \|.\|. . . \|..\|.. elyedsekkfyvrllfs
His_Phos_2	Histidine phosphatase superfamily (branch 2)	3-208	1.5e-14	46.6	In-house	149-347 (347)	alignment
Range on Protein: 3-208 Range on HMM: 149-347/347.0 DHDKVLRPYSMCPRYDQ-VVDGRNGMLEPRKFaQGSEMQRVIS-NVKSRlgMPKN-AELNVEVVEKMFmLCAFLTVNDNDTSWCSLFEE--EDLNVLEYY ... .. .. \|\|.... .. . . \| .. ..\|. .. ... .... ..\| \|. \|\|.\| ..\| ... . . ...\|... .\|. .... lkellregaescpafawppikvekrvvelvnk.lkkvmdenlakrlsal..ctgednllfkerweklf.reffeeekfdiskipelydtmkydalhnrql LDMWQYYEH-GYGHEITYKSICPLVAEIAQTIKSFTKKKI----PNGIFRFAHSGGIISLQSILSLYRDPIPLtagnyhklsnrtfrIARNAPMSSNIAF \|. ..\| \|.\|.\|. \| .\|. .... \|.\| .... .. \|.\| \|..\| ..\| \|. . .. ... \|..\|.\| \| edleelyklygigdeeklkigllllnpllkkilsdleetqpsrhaklrlyfthDshiytllnaLgleekiare..............aspelpyasqivf VLHECTDG-YKVQVLVN \|.\|. . . \|..\|.. elyedsekkfyvrllfs
0046349	Phosphoglycerate mutase-like	5-246	2.6e-36	118.7	In-house	142-392 (409)	alignment
Range on Protein: 5-246 Range on HMM: 142-392/409.0 DKVLRPYSMCPRYDQVVDGRNGM-LEPRKFA---------QGSEMQRVISNVKSRL-----GMPKNAElnVEVVEKMFMLCAFLTVN-DNDTSWCSLFEE \| .\|.\|.\|.\|\|..\|.... \| .\|. . .\|...... . .\|\| \|.... .\|.. .. .... \|.. .\|\|.\|\| . dtllppdslcpaldkllkenlkslsevleflvdealldlelldetkdllkklaerlnselpglnltdp..ldvasllydtllyetahglplppwcdlftp EDLNVLEYYLDMWQYYEHGYGhEITYKSICPLVAEIAQTIKSFTKKKI-------PNGIFRFAHSGGIISLQSILSLyrdpipltagnyhklSNRTFRIA \|.\|.\|\|.\|. \|. .\|\|..\|.\| \|... . .\|\|. \|\| . ... ...\| . .. \|\|\| . \|..\| \|.\| \| ..\|.\|\|. eelkvlayladleyyylygsg.elaklaggpllneilarledaisgknpvtfpldlklylyfaHdttiaallsaLgl...............fdrlfrss RNAPMSSNIAFVLHEC--TDGYKVQVLVNERLTVLPCCKSAvCKLDKFLECYEAIGSNC---DLEKMCKL . \|..\|\|..\| \|.\|\| ...\| \|.\|\|.\|.. \|\| \|.. \|.\|..\|.\|... . .\| \| .\|.\|.\| dippyasnlvfElyecpsdgeyyVrvlynggplplpgcgeg.cplsefkellkkrlpgcgltdfdklCpl
0049059	Phosphoglycerate mutase-like	6-245	9.6e-40	129.8	In-house	177-435 (435)	alignment
Range on Protein: 6-245 Range on HMM: 177-435/435.0 KVLrPYSMCPRYDQVVDGRNgmleprkfaQGSEMQRV-ISNVKSRLGMPKN-AELNVEVVEKMFMLCAFLTVNDND-----TSWCSLFEEEDLNVLEYYL \| \|\|..\|\|..\|..... ...\|.. . ......\| . .\|... \| .. \|\|.. \|.. . ..\|\|\|\| \|\|.\|.\|\|\|\|. dtl.pydscpafdellkell.........asdeflelflerilkllqellpglgltpsdvldlydlckydtlllgyahglplpfcslfteeelevleyla DMWQYYEHGYGHEITYKSICPLVAEIAQTIKSFTKKK-----------------IPNGIFRFAHSGGIISLQSILSLYRDPIPLTAGNYHKLS-NRTFRI \|. .\|\|..\|\|\|.\|\|.... .\|\|. \|\| . ... ... . .. \|\|\| . \|..\| \|.\| \|. \| .\|\|.\|.\|. . . .\|.\|\|. dlefyylygygdeiaklaggpllneilarledaingdstnlnltldsnpatfpldlklylyfaHdttiapllsaLglfddqlplpadntpfpeldrlfrt ARNAPMSSNIAFVLHECTD--GYKVQVLVNERLTVLPCCKSA---VCKLDKFLECYEAIGSNCDLEKmCK . .\|..\|\|..\| \|.\|\| \| .\| \|.\|\|.\|.. \|\|.\|.\| \|.\|\|.\|.\|... . ...\| .. \|. seivPyasnlvfElyecpdgneyyVrvlyngkvlplpgcgsgpgglCplddFkelvkkflpgddfde.Cg
0048439	Phosphoglycerate mutase-like	10-232	1.3e-30	100.0	In-house	131-387 (391)	alignment
Range on Protein: 10-232 Range on HMM: 131-387/391.0 PYSMCPRYDQVVDGRNGMLEPRKFAQgSEMQRVISNVKSRLGMPKNAelnvEVVEKMFMLCAFLTVNDND-----TSWCSLFEEEDLNVLEYYLDMW--- \|. .\|\|.... .. \|\| ... ....\|. ... \|\|. ..\| \| \|. .\| \|\|\|..\|. ...\|.\|\|. .\| ..\|\|. .. pintcplledlllldalsalprfyls.eilerlaevlnrvlglnlta....edvlslfdlcaketaalgsllklssplcdlftlydtllyeyahglplpe ----------------------QYYEHGYGhEITYKSICPLVAEIAQTIkSFTKKKIPNGIFRFAHSGGIISLQSILSLYRDPIPLTAGNyhklsnrtfr .\|\| .\|.\| \|\|.. ...\|\|. \|\| . . . .. \| .. \|\|\| . \|..\| \|.\| \|. \|..\|\|.\|.. wltdellspellkqladlvnelyyyltgsg.eiaklaggpllneilddl.vangpsdpklylyfaHdttiaallsaLglfndtlplpadl.......... iarnAPMSSNIAFVLHEC--TDGYKVQVLVNER--------------------LTVLPCCKSA---VCKLDKFLECYE \|..\|\|..\| \|.\|\| ...\| \|.\|\|.\|.. . .\|\| \|.\| \|.\|\|.\|.\|... ....ppyasnlvfElyecpsdgeyyVrvlynggtldlprdltlldldefllrlvlplpgcgsgpgglCplddFvelvk

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