Synonym: YCR095C, OCA4
Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
---|---|---|---|---|---|---|---|---|---|
0051082 | (Phosphotyrosine protein) phosphatases II | 1-191 | 3.9e-16 | 54.5 | In-house | 1-137 (151) | alignment | ||
Range on Protein: 1-191
Range on HMM: 1-137/151.0
MLVPPANFGIAEEGIYRCSKVETLNLSFLETLNLKTAIFIGGQEPSKFFKDFFTRSSIKWIVLRMSDFSAAAvpvksssvsnanlysnnnstlslqeekk
.|... ||. ..|.||.. .| .|..|..|| . . . |. ......... .|... . . |...
plsdyinfsyvtgglyrsggpladflellkelgiktivnlrseeergycpeylpelgievlhipildwpdpg............................
kstangsqnsttgdpviqeelayhltdnddlMLIKSTCLKRTFKTLLNVDNYNVLL-----VDKTALVIGILRKIQKWNIASIINEYRLFSGKNRN
. . ... .. ||. .|..|| .. |....................||||. . .
...............................lplsfdavleflellldkkngpvlvHCsaGkgRTGtlvalylmllgvsleealeeyrlkrpgvvq
|
|||||||||
subfamily_OCA_pd | Subfamily OCA | 2-199 | 1.1e-38 | 123.3 | In-house | 144-279 (282) | alignment | ||
Range on Protein: 2-199
Range on HMM: 144-279/282.0
LVPPANFGIAEE--------GIYRCSKVETLNLSFL-ETLNLKTAIFIGGQE-PSKFFKDFFTRSSIKWIVLRMsdfsaaavpvksssvsnanlysnnns
||||.||...|| |..|....|..||.|| ..|.||||......| ......||...|.||...||.
lvpprnfslveeykdkpvisgllrlllpeeenlpfLidrlglktaliLdaeeveretiadflasseiklvslrn..........................
tlslqeekkkstangsqnsttgdpviqeelayhltdnddlmlikstclkRTFKTLLNVDNYNVLL--VDKTALVIGILRKIQKWNIASIINEYRLFSG-K
...|.||..|||.|.| ..||..|...|||..|....||..||..|.. .
.................................................evlkdlldndnyavelscqaktdtvlkvLrkdkkygstsiyleyigFtled
NRNYFAETFLE
.... . . |
qeslksillie
|
|||||||||
Y_phosphatase2 | Tyrosine phosphatase family | 2-66 | 5.1e-11 | 34.6 | Pfam-A | 1-65 (165) | alignment | ||
Range on Protein: 2-66
Range on HMM: 1-65/165.0
LVPPANFGIAEEGIYRCSKVETLNLSFLETLNLKTAIFIGGQEPSKFFKDFFTRSSIKWIVLRMS
|||| ||. .|...|| | . |.|||..|.||| | . .| |. . |.. || . . ..
lvpplnFsaveselyrssyprasnfsflksLkLktiislspeeesqdelqfleeekiklyhiaie
|
|||||||||
Y_phosphatase2 | Tyrosine phosphatase family | 62-219 | 3.6e-48 | 155.5 | Pfam-A | 1-164 (165) | alignment | ||
Range on Protein: 62-219
Range on HMM: 1-164/165.0
VLRMSDFSAAAVPVKSSSVSNANLYSNNNStLSLQEEKKKSTANGSQNSTTG-DPVIQEELAYHLTDNDD-LMLIKSTCLKRTFKTLLNVDNYNVLLVD-
......|||.......||...|...|...| |.|......|... ||..... .. ..........|.. |. |||..||...|.|||..||.|||..
lvpplnFsaveselyrssyprasnfsflks.LkLktiislspeeesqdelqfleeekiklyhiaiesnkeelveiksdllkkalklllnkenypvllhck
----KTALVIGILRKIQKWNIASIINEYRLFSGKNRNYFAETFLEIINIEIEQEKDNKTIVDNKA
.|.||||.|||.|||..|||.||||.|||.......|.|.|....|.|.||.||.....|.
rGkhrtglvigclRklqkWslasilnEyrrFsgskkrivdeefienfdselevekknkklkvlks
|