Gene INP51 in Saccharomyces cerevisiae

Synonym: SJL1, YIL002C, INP51

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family Sac
Subfamily Synaptojanin
Protein sequence
ID Type Fasta BLAST phosphatome Note
ScerP033_AA protein Get Run
ScerP033_AA_225-516 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
Sac_COG5329 1-946 0.0 1064.0 In-house 1-934 (1070) alignment 
Range on Protein: 1-946
Range on HMM: 1-934/1070.0
MRLFIGRRS-RSIVISSNNYCLSFQRLrsipGASSQQRQLSKTPSVTIKSYPDTDLSSDSNYLEVKSCIFNGllglvCLNGDIYVAVISGVQNVGfprwk
|........ |||.|.||.|.|.|.||    ..............|...........|.|.. |.......      .|.|.....||.|...|.     
MkillsekktRsiaivsnkyalvfrrl....svknselsvcaaelvavselkkegfrslssaheiygvlGli.....elegslflivitgkskva.....

lidhQVRPSESIYKVLDVDFYSLENDVFDYLLCERSEQNYDKLIHEHPCGPLKKLFSDGTFYYSRDFDISNIVKNHgLSHNLEYTVDNQDLSFIWNANLA
    ||.|.|.|||.|.|||.||.|...|....|..|....||..||||..||||.|.|.||.|.||||.|..... |...||..||..| .|.||..|.
....qvipgetiykilavdfislnnnkwddeeiesdeasteklrsehpcselkkLlsngsFYfStdfditntLqkr.lkeelelsvdtadeefmwnsfll

SEVINWRSKISNEEKQLFANAGFLTFVIRGYCKTALIEDGPNTASITIISRISTESKQDTLELEGISEDGRVSLFVETEIVVTTEKFIFSYTQVNGSIPL
.|.||.|||.|..||||..||||||.||||...|. |.....|...|.|||.|......... .|...||.|..|||||..|......||.|||.||||.
eelinyrsklsslekqlldnagFlttvIrGFaetvfikvkkktiaLtlISRrSskragtRflarGvDddGnvanFVETEqIvyssqycfsFtQvRGSiPi

FWESVeSQLLYGKKIKVTKDSIEAQGAFDRHFDNLTSKYGVVSIVNIIKPKSESQEKLALTYKDCAESKGIKITNIEYSSSVLTK-----SPHKLLYLLK
|||.. |..|.|.||..|..|...| |||.|||.|..||| |.|||..|.||...|... ..|....|. .||...|..... |.     ...|||.|..
FWeqe.snsligpkiqitrsseatqsafdkHFdklfekYGdvhivNLlktKssEieLseryekhlklsekpkihlteFdfhketsqdgfddvkkLlplie

QDIYEFGAFAYDISRGIYFAKQTGVLRISAFDSIEKPNTVERLVS-KEVLELTTNEIDVFELTS-PFLDAHDKLWSENYYWLDRTYTKHTKNSGKYTKVY
||..|||.|.||...|.....|.||.|....|.....|....|.| ...|| ......... .. .||.....||..|.......||.........|...
qdllefgyfsydvkegkliseQdGVfRtNClDCLDRTNviQqliskrvlleqfrsikvisaiddedflqklneLWadnGDaisqiYTGtgalkssftrkg

SKLFGSRVRLYDPLHIYISQYLKQLRSKYTFEKDISIFAGTFNISGKIPKDDIKDWIFPKSMSKEDEMADLYVIGLEEVVELTPGHMLATDPYVRQFWEK
.. . .... ... . ..... .. ..|........... ........................|...|. ..|  ..... .. .............||
krsiagalsDatkSvsRmyinnfvDkekQdaidllLgklpdqeavelydpineyvnlrlrkseseftaaknvsiftltfnsngessstkllklllkvlek

KILTLLNGPGRKKKYIRLWSTQLGGILLLLFMNETEYSKVKHIEGDVKKTGFGGMASNKGAVAVSFKYSATRFCVLVSHLAAGLENVEQRHNDYKTIAKS
|| .|..|. ...|.|.|....|. .    |..|.|...|...| ..||...  ..|...|....||.||....| .|. |||........|..|...|.
kisklvvgvvglqkqiwlelillssltksefkeeeeenlvrkyenklkkkkleqsssqltalfilfkksadikevvssekaagrktgtgglnankgavki

IRFSKGLRIKDHDAIIWMGDFNYRILMSNEDVRRKIVSKEYASLFEKDQLNQQMIAGESFPYFHEMAIDFPPTYKFDPGTKNYDTSEKMRIPAWTDRILS
...|.||.....||.....|.|... .|......|.||||........||....||........|...........|...|.|||.............|.
eaeseglvfifvdasaaledenesernskyesitkrvskeipkmikdhqlilldiainltidydeeevraekekeidrelkkydtkqeltekvfvekvle

RGEVLEQLEYKCCEDILFSDHRPVYAIFRARVTVVDEQKKTTLGTQIYEKIMERLEGLDDDEKIAVLSDDAFVIESFEGSDSIAGPTHSPTPIPEPKRGR
..||.|.||.|..||....|....|...|.|.....|.|||.|.....|.............||||||.|.......|.|..||..|..|...||.....
ptevpellekksyeddndtdtedayrklrtrkliqkeekktelaysslelkisdhkpvtaevkiavlskdekkklklelslkiayktekpselpeepdel

KLPPPSSDLKKWWIGSGKQVKVVLDVDPAVYMINPKRDPNPFVENEDEPLFIER
.....|.||.|......||.||| .||....|..||..|....|...||....|
ssallskdlekisldatkqskvvklvdlddtmaqpkalpsksseqpsepeaslr
subfamily_INPP5F_pd Subfamily INPP5F 2-560 8.3e-166 544.7 In-house 1-526 (951) alignment 
Range on Protein: 2-560
Range on HMM: 1-526/951.0
RLFIGRRSRSIVISSNNYCLSFQRLRSIPGASSQQRQLSKTPSVTIKSYPDTDLS-SDSNYLEVKSCifNGLLGLVCLNGDIYVAVISGVQNVGFPRWKL
||..|........|.....|.... .||.|....|.. ||...|.|......||| .||..||...|  .||.||..|.|.|.||.|.|...| ...|.|
rlvygvigkillvseeerkLvivsessilgllpvqkkeskkevvaiervakldlsekdskelekeec..tgliglielegkiivatiegkskvnnkkwdl

IDHQVRPSesiykvldvdfyslendvfdYLLCERSEQNYDKLIHEHPCGPLKKLFSDGTFYYSRDFDISNIVKNHGLSHNLEYTVDNqDLSFIWNANLAS
||......                    . |.|..|||... ...... .||||.|||.||||.|||..|.....||... |.| |. | .|.||..|..
ididssgy....................lqlkeekeqneeeklekrlleelkkllsdgsFYysldfDltntlqkrgleeksestddw.derFfWNkfllk

EVINWRSKISNEekqlfanagFLTFVIRGYCKTALIEDGPNTASITIISRISTESKQDTLELEGISEDGRVSLFVETEIVVTTEKFIFSYTQVNGSIPLF
..||.|.|...|         |||.||.|...|. |.  ....|.|.|||.|......... .||..||.|. |||||.....||...|.||..||.|.|
dlinyrdkldke.........fltpviqGfvetkeisieklkvsltlisrrSrkragtrfkrrGidddgnvAnfvEtElilsvekyvlsftqirGSvPvf

WESVesQLLYGKKIKVTKDSIEAQGAFDRHFDNLTSKYGVVSIVNIIKPkSESQEKLALTYKD------CAESKGIKITNIEYSSSVLTKSPHKLLYLLK
||..  . .| .|||.|... |.|.|||.||.....||| |.|||.... ..|..||. .||.      ..... ||....|..|.  .....||..|.|
weqs..gkkykpkikitrseeetqpaFdehfkeqlkkygkvvivnllsq.kssekklskaykeqllkleskdvflikfdfheetsgekfenvsklielik

QDIYEFGAFAYDISRgIYFAKQTGVLRISAFDSIEKPNTVERLVSKEVLELTTNEIDVFELTSP-----FLDAHDKLWSENYYWLDRTYTKHTKNSGKYT
..|.|.|.|.||...  ....|.||.|....|.....|.|.. .||.||||.......|| .|.     .|....|||..|.....|.|.......|..|
neikevgyfsydvke.kviseqkgvfRtnclDcldrtNvvqqaiskavlelqleklglfepessiddeellqklkklWadngdaisrqYagtnalkgdlt

KV-YSKLFGSRVRLYDPLHIYisqYLKQLRSKYTfEKDISIfagtfnISGKIPKDDIKDWIFPKSMSKEDEM
.  ..||.|.....|.....|   ||.....||. .|.|..      ..||.||......|.||...||.|.
rkgerklaGvlkdgyksvsry...ylnnfkdkyr.qkvidl......llGklpkqevvelidpkkeekeeel
subfamily_SAC1_pd Subfamily SAC1 69-470 5.8e-39 125.0 In-house 7-386 (458) alignment 
Range on Protein: 69-470
Range on HMM: 7-386/458.0
FNGLLGLVCLNGDIYVAVISGVQNVGfprwklidhQVrPSESIYKVLDVDFYSLENDVFDYLL-CERSEQNYDKLihehpcgpLKKLFSDGTFYYSRDFD
. |.||.. |    |. ||  ...||         ..  .. ||.| ||.  ....  ..     ...|..| ||        |.....  |||.| ..|
iagilGiikLlsgkylivitkkeevg.........ri.ngkviyrvadveiipvkknslslteeqkkeekeylkl........lelvlksetfYfsytyd

ISNIVKNHGL-SHN---LEYTVDNQDLSFIWNANLASEVINwRSKISNeekqlfanagFLTFVIRGYCKTALIEDGPNTASITIISRISTESKQDTLELE
..| .. .   ...    .  ..  |  |.||  | ... . . ....          |.  ||.|. |.  ..   .. . ..||| |           
ltnslqrlekvtsaalkerslleradeRffwnkhlledlrk.epeles..........filPvikGfikikelslnakeikfilisRRsifRaGtRyfvR

GISEDGRVSLFVETEIVVTTEKFIFSYTQVNGSIPLFWESVeSQLLYGKKIKVTkDSIEAQGAFDRHFDNLTSKYGVVSIVNIIKPKSeSQEKLALTYKD
|. ..|.|. ||||| .|..|| ..|. || |||||.|.   ..| |  |.|.. .| . . ||..|.|.....||   .||..  |  | .||  .|..
GvdkeGnvanfvEtEqiveaekaltsFvqvRGsiPllWsqk.pnLkykPkvkls.esedsldafkkhldeqielygenvlvnLvdqkG.sEkklgeayes

CA---ESKGIKITNIEYSSSVLTKSPHKLLYL---LKQDIYEFGAFAYDISRGiYFAKQTGVLRISAFDSIEKPNTVERLVSKEVLELTTNEIDVFELTS
 .   ..| || .  .. .       ..|  |   |...  ..| |  . ..  . ..|.||.|    |.... | |  |...|||.   ....| .  |
vvralnkkkikyvafDFHkeCrkmrwdrlklLidqlekelsqegyflkseekk.ivkeqkgvvRtnCiDcLDRtnvvqsllarevLqkqleslgvlates

PFLDAHDKLWSEN
 . |... . |  
kledsaeletsfk
Syja_N SacI homology domain 70-377 1.7e-64 209.0 Pfam-A 2-308 (319) alignment 
Range on Protein: 70-377
Range on HMM: 2-308/319.0
NGLLGLVCLNGDIYVAVISGVQNVGFPRwklidhqvrPSESIYKVLDVDFYSLENDVFDYLLCERsEQNYDKLIHEHPCGPLKKLFSDGTFYYSRDFDIS
.|.|||. |. . |. ||.. ..|. .|         ....|||. .|.|..|...  .   .|. |.. ..  .|...  ||||.|.|.||.| |.|..
ygilGlirllsesyllvitkrekvakir.........gehpiykiksvefiplnseeeessaiee.ekeeeekeeekllkllkkllssgsfYfSydyDlt

NIVKNHGLSHNLEY--------TVDNQDLSFIWNANLASEVINWRskisneekqlFANAGFLTFVIRGYCKTALIEDG-PNTASITIISRISTESKQDTL
. ....  ... |         .....|  |.|| || ...|...          ..   .|...|.|..... ||    .....|.||| |.. .    
rslqrksekeeeekeeeskslpllkevderFvWNrnllkplielk..........ldlsrwllpliqGfveqrsievkskkkveltLIsRrsvkraGtRy

ELEGISEDGRVSLFVETEIVVT-T-E--KFIFSYTQVNGSIPLFWESvESQLLYGKKIKVTKDSIEAQGAFDRHFDNLTSKYGVVSIVNIIkPKSESQEK
   || .|| |. ||||| .|. . |  | .||..|. ||.|||||  .|.| . .|||.|..| ..| ||..||..|...|| . .||..  |.....|
lrRGidddGnvANfvEtEqivsekkeeskrvfSfvqiRGSvPlfWeq.asnlslkpkikitrsseasqkafkkHfkklikrYgkivvvnLl.ekkgrEkk

LALTYKDCAESK--------GIKITNIEY
|  .|......          .|......
LseayeelinklnkklkekkklkyiefDf
Syja_N SacI homology domain 70-377 1.7e-64 209.0 In-house 2-308 (319) alignment 
Range on Protein: 70-377
Range on HMM: 2-308/319.0
NGLLGLVCLNGDIYVAVISGVQNVGFPRwklidhqvrPSESIYKVLDVDFYSLENDVFDYLLCERsEQNYDKLIHEHPCGPLKKLFSDGTFYYSRDFDIS
.|.|||. |. . |. ||.. ..|. .|         ....|||. .|.|..|...  .   .|. |.. ..  .|...  ||||.|.|.||.| |.|..
ygilGlirllsesyllvitkrekvakir.........gehpiykiksvefiplnseeeessaiee.ekeeeekeeekllkllkkllssgsfYfSydyDlt

NIVKNHGLSHNLEY--------TVDNQDLSFIWNANLASEVINWRskisneekqlFANAGFLTFVIRGYCKTALIEDG-PNTASITIISRISTESKQDTL
. ....  ... |         .....|  |.|| || ...|...          ..   .|...|.|..... ||    .....|.||| |.. .    
rslqrksekeeeekeeeskslpllkevderFvWNrnllkplielk..........ldlsrwllpliqGfveqrsievkskkkveltLIsRrsvkraGtRy

ELEGISEDGRVSLFVETEIVVT-T-E--KFIFSYTQVNGSIPLFWESvESQLLYGKKIKVTKDSIEAQGAFDRHFDNLTSKYGVVSIVNIIkPKSESQEK
   || .|| |. ||||| .|. . |  | .||..|. ||.|||||  .|.| . .|||.|..| ..| ||..||..|...|| . .||..  |.....|
lrRGidddGnvANfvEtEqivsekkeeskrvfSfvqiRGSvPlfWeq.asnlslkpkikitrsseasqkafkkHfkklikrYgkivvvnLl.ekkgrEkk

LALTYKDCAESK--------GIKITNIEY
|  .|......          .|......
LseayeelinklnkklkekkklkyiefDf
subfamily_Synaptojanin_pd Subfamily Synaptojanin 109-487 2.7e-39 126.2 In-house 32-398 (754) alignment 
Range on Protein: 109-487
Range on HMM: 32-398/754.0
ESIYKVLDVDFYSLENDVFDYLLCERSEQnyDKLIHehpcgpLKKLFSDGTFYYSRDFDISNIVKNHGLSHNlEYTVDNQDLSFIWNANLASEVINWrsK
.|. |. |.. . . .  . .|  | |..  |..|.      ||||.. ||||.|   | .. ..    ... ... ...| .|.||  |   . ..  .
ksvGkisdaeifkitstelvslrseasde..driie......lkkllasgtfyfsssadsasrldlslsaqr.rkqeesednrffWnrslhlhlqrf..g

ISNEEkqlfanagFLTFVIRGYCKTALIEDGPNTASITIISRISTESKQDTLELEGISEDGRVSLFVETEIVVTTEKFIFSYTQVNGSIPLFWESVESQL
.. ..        .|. |..|  .   .  | ..| ...|||.|.|     ..  |. ..|.|. ||||| |.. .. . |. |. ||.|||||    | 
vncdd........WllkvmcGsveirtvyagakqakaalisrlsceraGtrfnvrGvndeGnvanfveteqvillddkvtsfvqirGsvPlfWeqPGlqv

lYGKKIKVTKDSIEAQGAFDRHFDNLTSKYGVVSIVNIIKPKsESQEKLALTYKDC----AESKGIKITNIEYSSSVLTKSPHKLLYLLKQDIYE-FGAF
   .|.|....   .. |||||...| ..|| | |||..  | |..| |  ..|.     . .| ... . .| ..| ..  .||  |||. . . .  .
.GshkvklsrgfeasaaafdrhleqlkeryGevvivnllGsk.egeevlskafkkhlkasehakdvpfvkfdyhqkvkggkkeklekllkkqlklflesa

AY-DISRGIYFAKQTGVLRISAFDSIEKPNTVERLVSKEVLELTTNEIDVF---ELTSPFLDAHDKLWSENYYWLDRTYTKHTKNSGK
 .   . .    .||||||.  .| ... |.|  ... ||||   . ...    .. | | ... .|||.|   . . |.     .||
sfflskgkevekeqtGvlrvnClDCldrtnavqtvlglevlekqlealklsskesvvsrfeevfkslWsknGdeiskiyaGtgalegk
subfamily_FIG4_pd Subfamily FIG4 110-449 3.1e-21 66.3 In-house 101-454 (569) alignment 
Range on Protein: 110-449
Range on HMM: 101-454/569.0
SIYKVLDVDFYSLENDVFDyLLCERSEQNYDKLIHEhpcgplkkLFSDGTFYYSRDFDISNIVKNHGL----SHNLEYTVDNQDLSFIWNANLASEVINW
 |||. |... ....|          |. | || ..        .    .||.|  .|... ...  |     .. | ..|..| .   .   |.|   |
aiykiedialikitedskk.sekssdearylklfkd........vdltknfyfsysydltrtlqtnlllsdsnrekekaedrvditieakkldanekfvW

RSKISNEEKQLFANAGFLTFVIRGYCKTALIEDGPNTASITIISRISTESKQDTLELEGISEDGRVSLFVETEIVV-------TTEKFIFSYTQVNGSIP
 ... .  |.   .  .|  .| |...   |.   .. ..|.|.| |..     .   |. ..| |.  |||| .|       .... . |..|. ||.|
nnflleplkdtvktfdWlleiihGfvsqskisvlgksiyvtliarrsskfaGarflkrGvnnkGdvaneveteqivheasegsldsdryssfvqlrGsvP

LFWESVESQLLYGKKIKVTKDSIEAQGAfDRHFDNLTSKYGV-VSIVNIIKPKSES--QEKLALTYKDCAES------KGIKITNIEYSSSVLTKSPH-K
|.|.  .|.|    .||. .    |. |  .|||.| ..||  . |.|..| |     ...|   .... |       .  |.. |..  .  .|| . .
lyWsqdasklvtkPpikidvvdPfasaa.alhfddlfqryGspiiilnlvkkkekrkresilleefeaaieylneflPeekklkyiswdmaraskskeen

LLY----LLKQDIYEFGAFAYdISRGIYFAKQTGVLRISAFDSIEKPNTVERLVSKEVLELTTNE
 |     . .. . . | |    ..    . |.|..|    |.... |.   ...|  |     .
vlevlekyaeksvkktGifls.apdlestkiqeGivrtnCvdcldrtnaaqfvigkvalgyqlks
subfamily_Synaptojanin_pd Subfamily Synaptojanin 511-793 3.6e-77 251.5 In-house 461-750 (754) alignment 
Range on Protein: 511-793
Range on HMM: 461-750/754.0
SQYLKQLRSKYTFEKDISIFAGTFNISGK-------IPKDDIKDWIFPKSMSKE---DEMADLYVIGLEEVVELTPGHMLATDPYVRQFWEKKILTLLng
 . | .  ...|  | . |. ||.|. |        . .. ..||.. .. ..     ..||.| ||.||.|.|. . .. .    |. | ... . |  
lkelvereqelteakklricvgtwnvnggkqlrsvalknesltdwlldlpelsgaedskpadiyaiGfeelvdlnasnlvsasttnrkewaeelqkvl..

pGRKKKYIRLWSTQLGGILLLLFMNETEYSKVKHIEGDVKKTGFGGMASNKGAVAVSFKYSATRFCVLVSHLAAGLENVEQRHNDYKTIAKSIRFSKGLR
 .|..||. | |.|| |. | .|.  .    .. .  .  |||.|| | ||||||. ..  .| .| . ||||||  .|..| .||..||. |.|..|  
.srdakyvlltseqlvGvclfvfvrpklvpfirdvavstvktGlgGaaGnkGavairlllhstslCfiCshlaagqskvkernedyaeiarkiafpmgrt

IKDHDAIIWMGDFNYRILMSNEDVRRKIVSKEYASLFEKDQLNQQMIAGESFPYFHEMAIDFPPTYKFDPGTKNYDTSEKMRIPAWTDRILSR
.. ||.. |.||||||| .....|.. . .|.|..| |.|||..|  .|. |  |.| .. | ||||.|  ...||||||.|.||||||.| |
leshdyvfWlGdfnyridlekdevkelvkkkdydklvendqltkqkkkgkvfkgfaegeltfaPtykydlfsddydtseklrvPaWtdrvlwr
Exo_endo_phos Endonuclease/Exonuclease/phosphatase family 532-813 6.3e-26 81.6 Pfam-A 1-249 (249) alignment 
Range on Protein: 532-813
Range on HMM: 1-249/249.0
GTFNISG-------KIPKDDIKDWIFPKSmskedemADLYVigLEEVVELtpghmlatdpYVRQFWEKKILTLLNGPGRKK--K-----YirlwstqlGG
.|.|..|       .  .|...|..   .       .|...  | ||.|            ........  . |. .|  |  .     .        ||
ltwNvlgwnarsdrakkldqladllqsed.......pDvll..LQEvded..........plsellatglaselgldgdgksggggggda........gg

ILLLLFMNETEYSKVKHIEGDVKKTGFG---GMASNKGAVAVSFKysATRFCVLVSHLAAGLENVE--QRhNDYKTIAKSIRFSKGLrikdhdAIIWMGD
. | |. .    .|....  .  |.| .   ..  |||.|.|.|.   ........||..| .. .  .|  ... |.|  ..|.|        .|..||
gglallskypldkkirrtfqldgkagiavprlssgnkgdvpvrfr..gktlalvntHltpgnrlrqrder.allaeidkladdsrgs......pvilaGD

FNYRILMSNedvrrkivskeyaslfekdqlnqqmiagesfPYFHEMAIDFPPTYKFDPGTKNY-------------DTSEKMRIPAWTDRILS-RGEVLE
||.|.  ..                               . |.| |.||.|...|| |....             ||.|| |.||..|.||  .|.. .
fNsrpdspd...............................kgfresaadflpgdgfddglrallphlllptspgttdtyekareparlDyilvssgwpal

QLEYKCCEDILF-SDH
....   ...   |||
vvsgasllsdrggSDH
subfamily_INPP5F_pd Subfamily INPP5F 561-946 4.7e-198 651.4 In-house 570-951 (951) alignment 
Range on Protein: 561-946
Range on HMM: 570-951/951.0
ADLYVIGLEEVVELTPGHMLATDPYVRQFWEKKILTLLNGPGRKKKYIRLWSTQLGGILLLLFMNETEYSKVKHIEGDVKKTGFGGMASNKGAVAVSFKY
.||.|.||.||||||.|..||.|.....||||.. .|||...|..||..|.|.||...|||||..|....|||..|||.|||||||.|.|||||||.|.|
pDlvvlGLqEvvELtaGsiLaaDyskskfWEklvedlLnkvsreekYlkLrseqlsslLlllfvredkakkvkevegdtkktGfgGlagnkGavavrfey

SATRFCVLVSHLAAGLENVEQRHNDYKTIAKSIRFSKGLRIKDHDAIIWMGDFNYRILMSNEDVRRKIVSKEYASLFEKDQLNQQMIAGESFPYFHEMAI
|||.||...||||||..|||.|..|||.||.||.||.. ||||||.|.|.||.|||| ..||.|||.....|...|.|.|||.....|||.|..|.|...
satsFcfvnsHlaAGasnveeRrsDykeiarsitFsrskrikdhDsifWlGDlnyRidlpneevRRelldqeidkLleyDqLtkeieaGevFegfkEetl

DFPPTYKFDPGTKNYDTSEKMRIPAWTDRILSRGEVLEQLEYKCCEDILFSDHRPVYAIFRARVTVVDEQKKTTLGTQIYEKIMERLEGLDDDEKIAVLS
.|.||||.|.||||||||||.|.|||||||...|||||.|||.....||.||||||||.|||.||||||.||.||....||...|.||...|.||...||
kFrPtYkyDlgtknYDtsekeRtPaWtDRiiykgevledLeyysdaeilisDHrPvyaafrakvtvvDekkkltLkkklyeeykeeleeasdsekdells

DDAFVIESFEGSDSIAGPTHSPTPIPEPKRGRklpPPSSDLKKWWIGSGKQVKVVLDVDPAVYMINPKRDpNPFVENEDEPLFIER
||....|..|..|.|............|||..   ..||...|...||.||||||||||.|......|.. ....|.|.|.|..|.
ddlekkeeaesldkivesaelklldldpkraq...dssssvskllsgsakqvkvvldvdsasvspdkkkv.vrppepeaeklvkep