Gene YMR1 in Saccharomyces cerevisiae

Synonym: YJR110W, YMR1

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family Myotubularin
Subfamily YMR1
Protein sequence
ID Type Fasta BLAST phosphatome Note
ScerP039_AA protein Get Run
ScerP039_AA_154-644 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
Myotub-related Myotubularin-like phosphatase domain 135-574 3.4e-147 482.8 Pfam-A 1-353 (353) alignment
Myotub-related Myotubularin-like phosphatase domain 135-574 3.4e-147 482.8 In-house 1-353 (353) alignment
subfamily_MTMR6_pd Subfamily MTMR6 136-452 3.1e-77 252.5 In-house 1-285 (397) alignment 
Range on Protein: 136-452
Range on HMM: 1-285/397.0
LYAFIYISNNleRKLPSPDSWDIYDPIKEFRRQGLDSKDetcpWRLSTVNEHYEFCPTYPSKLFVPRSTSDILLKHASKFRSQKRIPVLTYHHKATDCNI
|||| | ...   |  . . |. .|  .|. |.|. ..     | |. .|..|| | |||..|.||.|..  .|  .|||||..|.|||.|.||... .|
lyafsykpkk..dkeekvsGwklldlkaeytrmgvpnek....wtltdlnkdyelcdtyprelyvPksatkevlvgsskfrskgrlPvlsylhkeneaai

LRSSQPLPGLINqRSIQDEKLVWESFNsfCNKDIRRtkHVIVDARPRTNALAQMALGGGTENMDNYNffladnNMGVDkslklptvtrlFLGIDNIHIVS
 |.|||| |. . |. .||||.    .  .| . .     .||.||. ||||  | | | ||.|||.      |.  .           |.||.|||.. 
crcsqplsgfsa.rcledeklleairk..anpnsel..lyvvdtrpklnalankaagkGyenednys......nikfq...........fvgienihvmr

NTAAYMTEVIcqggDLNLPLEQNLIRSQKFSNWLKLNTLILKSVDMLLKSIIFNHSNVLVHCSDGWDRTSQVVSLLEICLDPFYRTFEGFMILVEKDWCS
.. . . ||.    .|. .  .. ... . |.|||    .|..  .. |..  .. .||||||||||||.||.|| .. |||.|||..||..|.||.| |
eslqkllevv....elksksvseflsglessgwlkhikavldasifiakavaeegasvlvhcsdGwdrtaqvcslasllldpyyrtikGflvliekewls

FGHRFLERSGHLNSDIR
|||.| ||.|.|..| .
fGhkfsercGlldedsk
subfamily_Ank-MTMR1_pd Subfamily Ank-MTMR1 144-450 1.8e-49 160.6 In-house 4-293 (405) alignment 
Range on Protein: 144-450
Range on HMM: 4-293/405.0
NNLERKLPSPDSWDIYDPIKEFRRQGL--DSKDET-CPWRLSTVNEHYEFCPTYPSKLFVPRSTSDILLKHASKFRSQKRIPVLTYHHKATDCNILRSSQ
|||. .  | | |..|.  ||. |  .  |..... | |.....| .|..| .|.| | |   . |  |..   |||. ||| |...  .... | | ||
nnlnsstssidgwevynqkkeylrfniyideenssncywkvtsinkeykmcssyssslvvlskaldkdlekifsfrskgripslswkdpssnasisrcsq

PLPGLINQRSIQDEKLVWESFNSFCnkdiRRTKhVIVDARPRTNALAQMALGGGTENMDNYnffladnnmgvdkslklPTVTRLFLGIDNIHIVSNTAAY
|| |.   |  .||  . .   |       .|   ..||||. ||.|. | | | ||. ||                 | .  .|. | |||.. ..   
plvgierarcpedelycsslalsap....sktl.ylidarpklnaiantangagfenihny.................pncklvfmnipnihvirkslek

MTEVICQGGDLNLPLEQNLI---RSQKFSNWLKLNTLILKSVDMlLKSIIFNHSNVLVHCSDGWDRTSQVVSLLEICLDPFYRTFEGFMILVEKDWCSFG
..  .      .   |   .      . . |.     ||..  .    .|..   .||||||||||| |. || .| |||.|||  || .|.||.| |||
lvlamkssardkdhtestdmrfwgyieetgwishiksileaatf.saelilkgnsilvhcsdgwdrtpqitsltqilldpyyrtivgfqvliekewlsfg

HRFLERSGHLNSD
|.|  | |||  .
hkfslrlghlpgn
subfamily_Dicty-MTMR1-like_pd Subfamily Dicty-MTMR1-like 152-640 1.8e-115 378.3 In-house 12-402 (404) alignment 
Range on Protein: 152-640
Range on HMM: 12-402/404.0
SPDSWDIYDPIKEFRRQGLDSKDetcPWRLSTVNEHYEFCPTYPSKLFVPRSTSDILLKHASKFRSQKRIPVLTYHHKATDCNILRSSQPLPGLINQRSI
  | | |||...|..|.|. |.    .||.|..| .||.|.|||. | || | ||  ||....|||..|||||...|. ....| |||||| || ..||.
ledgwliydaeeEykRlgikses...eWriskinsdyelcetYPkllvvPesisDeelkkvasfRskgRiPvlswrhrsknstitRssqplvGltksrse

QDEKLVwESFNSFCNKDIrrtKHVIVDARPRTNALAQMALGGGTENMDNYNffladnnmgvdkslklpTVTRLFLGIDNIHIVSNTAAYMTEVIcqggD-
.||||. .|... ...     . .|.||||..|| |. | | | |....|.                 ...  ||.|.||| . .    .....    . 
edEkli.nsirkaktqle...tlyildarpkanavansakgagyedisrye.................nceieflnienihelreslkklkkav....ns

---LnlplEQNLIRSQKFSNWLKLNTLILKSVDMLLKSIIFNHSNVLVHCSDGWDRTSQVVSLLEICLDPFYRTFEGFMILVEKDWCSFGHRFLERSGHl
        |.| .   . |.||   .|.|... .....|  ..|.||||||||||||||..|| ...|||.|||.|||..|.||.|.|||| | .|.|. 
iiek....eknwlselessrWldhiklllegskriveliekekssvlvhcsdgwDrtsqlsslsqllldpyyrtiegFivliekewlsfGhkfaqRigq.

nsdirfhdntmhsnfndvdtngddldigvntqddyaeddeggedetnlinlsriskkfnenfkLNKKSLKFVSPVFQQFLDCVYQLLTQNPDLFEFNERF
                                                                ..|| .  ||.| ||.||||||. |.|. |||||.|
...............................................................ttekssdersPiflqFidcvyqltkqfptsFeFnekf

LRRLVYHLYSCQYGTFLSNSEKEKFQQNLPNKTKSVWDYFRSRRKQFINPNFIQRKRSGMNEHDQNLEEEEKvewispDLKKVQWWWQLYGRK
| .....||||..|||| .||||. |.||...|.|.| .  . .....||..|..|.   .. ...  . ..      |.|... | ..| |.
likildalyscrfgtFLydsekeRqqnnlaketvslWalleankseylnplyilekkeqkenitssessssa......dikliklWseyylrw
subfamily_MTMR9_pd Subfamily MTMR9 153-447 5.1e-47 152.8 In-house 12-274 (393) alignment 
Range on Protein: 153-447
Range on HMM: 12-274/393.0
PDSWDIYDPIKEFRRQGLdskdETCPWRLSTVNEHYEFCPTYPSKLFVPRSTSDILLKHASKFRSQKRIPVLTYHHKATDCNILRSSQPLPGLINQRSIQ
 | .. .|. .|| ..       .. ||.|.||.... |..||... ||.. .|  ||  ..||.. |.|||.| ||.|   .||||||| |  ..|  .
edgysafdrenefaklis....asdewRissvNknfkvcasypesvivPkaiddeelkasaafreggrfPvLsylhketkavllrssqplcgssgkrcke

DEKLVWESFNSFcnkdirrTKHVIVDARPRTNALAQMALGGGTENMDNYNFFLADNnmgvdKSLklptvtrlflgiDNIHIVSNTAAYMTEViCQggDLN
||||.   ...         | .||| |  . | .... ||| |  ..|  .  ..     .||            ...... ...| . |. |.  |..
dekllnlvlkkl.......kkGlivdtrsksaaenarskgggietevkysqwkkas.....rsl............esvasiqdslakllea.cs..dag

LPLEqNLIRSQKFSNWLKLNTLILKSVDMLLKSIIFNHSNVLVHCSDGWDRTSQVVSLLEICLDPFYRTFEGFMILVEKDWCSFGHRFLERSGHL
|  . . ..  . |.||.  . .|. . .. ...  ... |.|| ..| | | ||.||  . ||| .|| .||. |.|..|   || | .|  ..
lstd.kflsrleksgwlsqvadlleaalvvaqcldeegapvvvhgeeGlDatlqvtsLaqlildpdaRtvrgfealiereWiqaGHPFasRaskv
0040695 (Phosphotyrosine protein) phosphatases II 154-641 1.9e-129 425.6 In-house 6-386 (388) alignment 
Range on Protein: 154-641
Range on HMM: 6-386/388.0
DSWDIYDPIKEFRRQGLDSKdetcPWRLSTVNEHYEFCPTYPSKLFVPRSTSDILLKHASKFRSQKRIPVLTYHHKATDCNILRSSQPLPGLINQRSIQD
..| .||...|. |.||. .    .||.|.|||.||.||.||..|.||.| || |||....|||..|||||.|.|. ... .|||||||.||...||..|
egwslydilrelkrlglgld....lwrisivNenyelcpsYPallvVPksisdellkrvarfrskgriPvlsyrhpnngavllRssqplvglllsrsled

EKLVWESFNSFCNKDirrtKHVIVDARPRTNALAQMALGGGTENMDNYNFfladnnmgvdkslklptVTRLFLGIDNIHIVSNTAAYMTEVIcqggdLNL
|||. . .... |..    | .|||.||..||||..|||||.||.|.| .                 .. .||.|.||| | ..   .....     ||.
eklleailkllpnls....kllivdlrpklnalanralgggvenedaypn.................aeliflnipnihvvreslqklldac.....lnv

PLEQNLIRSQKFSNWLKLNTLILKSVDMLLKSIIFNHSNVLVHCSDGWDRTSQVVSLLEICLDPFYRTFEGFMILVEKDWCSFGHRFLERSGHLNSDIrf
| ..||. . . |.||.|  |||... ...| . ...|.||||||||||||||..||....|||.|||.|||..|.||.|.||||.|..|.|||.|.|  
pdslnllslleesgwldliklilelavlivklldlgnssvlvhcsdgwdrtsqlssLaqllldPyYRTleGFqvLiekeWlsfghkfadRlghlesei..

hdntmhsnfndvdtngddldigvntqddyaeddeggedetnlinlsriskkfnenfklnkkSLKFVSPVFQQFLDCVYQLLTQNPDLFEFNERFLRRLVY
                                                             . | .|||| .|||||.||| |.|  ||||||.|..|..
.............................................................dskefsPvFllFLdcvwqLlrqfPtaFeFnerlLlfLad

HLYSCQYGTFLSNSEKEKFQQNLPNKTKSVWDYFRSRRKQFINPNFIQRKrsgmnehdqnleeeEKVEWISPDLKKVQWWWQLYGRKD
|||||..|||| |||||... .....| |.|.|. ||...|.||.. . .              . | . |... ....|...| | .
hlyscrfgtFlfnsekerlelsvsertlslwsyllsrkseflnplYdpss..............levllpslsvldlllWleyylrwl
subfamily_MTMR1_pd Subfamily MTMR1 154-450 4.3e-72 235.5 In-house 5-272 (389) alignment 
Range on Protein: 154-450
Range on HMM: 5-272/389.0
DSWDIYDPIKEFRRQGLDSKDetcPWRLSTVNEHYEFCPTYPSKLFVPRSTSDILLKHASKFRSQKRIPVLTYHHKATDCNILRSSQPLPGLINQRSIQD
| |..||| .|..|.|| ...    || ...|..||.|.|||..|.||...||  ||....|||..|.|||.. .| ... |||.|||| || ..|| .|
dGWkvydpeaelerlgllnek...lWritklnkkyelcdtYpavlvvpkvvsdedlkkvaafrskgRlPvlswlnkenqavilrasqplvGlsgkrsked

EKLVWESFNsfCNKdiRRTKHVIVDARPRTNALAQMALGGGTENMDNYNffladnNMGVdkslklptvtrLFLGIDNIHIVSNTAAYMTEVICQGGDlnl
||.. .  .  .|.  ...| .|.|||...|| |. | |.|.|. ..|.      |. .           .|| |.|||.| .    . |..    |   
ekylqaile..ana..qsekllildarssvnavankakgkgyeseeaYk......nael...........ifldihnihvvReslkklkelvlpnvd...

plEQNLIRSQKFSNWLKLNTLILKSVDMLLKSIIFNHSNVLVHCSDGWDRTSQVVSLLEICLDPFYRTFEGFMILVEKDWCSFGHRFLERSGHLNSD
  ... . .   ..||.   |||..   . ...  ....||||||||||||.|..||  . ||..||| ||| .|.||.|.||||.| || || ...
..dkkwlsalestkWlehiklilagavkivekvetektsvlvhcsdGWDRtaqltsLamlllDsyyRtieGfevliekeWlsfGHkfkeRlghgdkn
subfamily_pats1_pd Subfamily pats1 154-237 7e-09 26.6 In-house 4-82 (691) alignment 
Range on Protein: 154-237
Range on HMM: 4-82/691.0
DSWDIYDPIKEFRRQGLDSKDEtcpWRLSTVNEhYEFCPTYPSKLFVPRSTSDILLKHASKFRsQKRIPVLTYHHKATDCNILR
. .||| ...|..| .||   .   ||  .. .  . .  || .  ||.. || ||.   . | . .||||.. ...    ..|
eifdiyslliegqrlkldldkd...wrvvefls.rdlseiyPkrilvPklvsdellvsyvrkr.sskiPvlswsnqnnksslfr
subfamily_MTMR3_pd Subfamily MTMR3 161-268 2e-26 85.7 In-house 29-132 (442) alignment 
Range on Protein: 161-268
Range on HMM: 29-132/442.0
PIKEFRRQGLDSKDetcPWRLSTVNEHYEFCPTYPSKLFVPRSTSDILLKHASKFRSQKRIPVLTYHHKATDCNILRSSQPLPGLINQRSIQDEKLVWES
  .|. |.|.| |.    ||.|.||.....|..||.|| || | .|  ||....||| ||.|.. . || . . . |.|||  |..  |. .||||. . 
lkeeverlGfdlke...awrisdvnsdfklCssyPkklivPksitdddlkkvasfrslkrlPavvwrhkkngavlarcsqPevgwlgWrnaedekllkai

FNSfCNKD
 .. |. |
aka.cald
subfamily_MTMR5_pd Subfamily MTMR5 162-241 6.4e-17 53.5 In-house 11-93 (483) alignment 
Range on Protein: 162-241
Range on HMM: 11-93/483.0
IKEFRRQGLDSK---DETCPWRLSTVNEHYEFCPTYPSKLFVPRSTSDILLKHASKFRSQKRIPVLTYHHKATDCNILRSSQP
.....| ||..     .. ..|.|.||..|. | .||. . || ..||  ... .|   |.|.|| |..|. .   ..||...
vqdykRlGlgalngaskrgkfrisevNkkytvcrsYPalivvPsevsddsiarvakcfrqnRlPvvtWrhernkalLiRsggf
subfamily_MTMR10_pd Subfamily MTMR10 171-249 4.3e-08 24.3 In-house 18-96 (380) alignment 
Range on Protein: 171-249
Range on HMM: 18-96/380.0
DSKDETCPWRLSTVNEHYEFCPTYPSKLFVPRSTSDILLKHASKFRSQKRIPVLTYHHKATDCNILRSSQPLPGLINQR
. |  .. .. ...||  . ..|.| ...||.| ||  .. .|.   . | |.....|  .   .. | .  .  ....
ekktvsdaivvllknelfaaaqtlPqyfvvpnslsdsdverlsrhykesRfplwvwshakgaallrlsalqeaesadke
subfamily_MTMR3_pd Subfamily MTMR3 271-448 2.4e-37 121.7 In-house 172-327 (442) alignment 
Range on Protein: 271-448
Range on HMM: 172-327/442.0
RTKHVIVDARPRTNALAQMALGGGTENMDNYNffladnNMGVdkslklptvtrLFLGIDNIHIVSNTAAYMTEVICQGGDlnlplEQNLIRSQKFSNWLK
  | .|||||  | |.|  | ||| |. . |.      |  |            |||. ||| | ..  .. ... |. |     |.|.. . .  .||.
kkkllivdarsytaafanrakgGGceleeyyp......ncev...........vflglanihavrksfnslrallsqspd.....esnwlsalektkWlq

LNTLILKSVDMLLKSIIFNHSNVLVHCSDGWDRTSQVVSLLEICLDPFYRTFEGFMILVEKDWCSFGHRFLERSGHLN
  . .||.   . ...  .   ||||||||||||.|.|.| ...|||.||| ||| .|||..| .|||.| .|.|| .
nlsvllkaavkvveavdkegrpvlvhCsdGWdrttqivalakllldpyyrtleGfkvlvereWldfGhkfadrcghge
subfamily_MTMR5_pd Subfamily MTMR5 357-449 5.5e-26 83.4 In-house 264-356 (483) alignment 
Range on Protein: 357-449
Range on HMM: 264-356/483.0
QNLIRSQKFSNWLKLNTLILKSVDMLLKSIIFNHSNVLVHCSDGWDRTSQVVSLLEICLDPFYRTFEGFMILVEKDWCSFGHRFLERSGHLNS
|  ..| . |.||.    .|.   .. . .  . | |||   |||| |.||.|| ...|||.|||.||| .||||.| .||||| .|| . .|
qsFlksvedseWlqqissllqlsgavvdlldlqgssvlvslEdGwdvtaqvsslaqllldpyYRtleGFkvLveKEWLafGHrFtkrsnqtls
subfamily_MTMR14_pd Subfamily MTMR14 362-445 6.4e-09 27.1 In-house 240-329 (357) alignment 
Range on Protein: 362-445
Range on HMM: 240-329/357.0
SQKFSNWlKLNTLILKSVDMLLKSIIFNH-SNVLVHCSDGWDRTSQVVSLLEICLDPF------YRTFEGFMILVEKDWCSFGHRFLERSG
 ... .|  | .|    . .|||..  .. | .||||  |||||   |||| . |          .. |   . |  ||  |||.. .|  
wseykkW.dlvaltqnylklllkyvkededsGllvhcisGWdrtPlfvsllrlslWadglihqslsaaellyltvaydWflfghqlpdrlk
subfamily_MTMR10_pd Subfamily MTMR10 366-635 4.1e-29 93.5 In-house 162-372 (380) alignment 
Range on Protein: 366-635
Range on HMM: 162-372/380.0
SNWLKLNTLILKSVDMLLKSIIFNHSNVLVHCSDGWDRTSQVVSLLEICLDPFYRTFEGFMILVEKDWCSFGHRFLERSGHLNSDIRFHDntmhsnfndv
..||..  |.|. .  . | .  .. .|..  |.| |    | ||  ..|||.||| .||  |..| | . || ||.| ||. ..               
trWLayvrlclstasdavktvvekkrsvilqesegrDlscvvaSLaqlmldphyrtisGfqsliqkewvaaghpfldrlghikpsekses..........

dtngddldigvntqddyaeddeggedetnlinlsriskkfnenfklnkkslkfvsPVFQQFLDCVYQLLTQNPDLFEFNERFLRRLVYHLYSCQYGTFLS
                                                       |||  |||||.|||.| |. |||.|.||  |. . .|. ..|||.
.......................................................pvfllFldcvdqlleqfpseFeFtetfLialwdsshsgifltflf

NSEKEKFQQ----NLPNKTKSVWDYFRSRRKQFINPNFIQRKRSGMNEHDQNLEEEEKVEWISPDLK--KVQWWWQ
|||... ..    ..   .|| . .  .   .    . .  .  . ..   . ..  . |.| | |.   .| | .
nseeqrlkavvsssplliakselkendllkdeldyrqglyaeiiksirrlaaaksylrseiirPllqipdiqlWde
subfamily_pats1_pd Subfamily pats1 366-596 5.3e-27 86.5 In-house 376-629 (691) alignment 
Range on Protein: 366-596
Range on HMM: 376-629/691.0
SNWLKLNTLILKSVDMLLKsIIFNHSNVLV-HCSDGWDRTSQV---VSLLEICLDPFYRTFEGFMILVEKDWCSFGHRFLERSGHLNSDIRFHDNTMHSN
| |.    |.|...  . .  . . | ||.   .|. . . ..    ||  . .||||||..||..|.||.| |.|. | ... | .||    .|  . |
skwvdsvkllleaavkvsn.lldeGssvllknsidsPlieldlasisslaqvlsdPfyrtldGfkvliekewlsyGfPfskinyhkesddlnnnngnken

FNDVDTNGDDLDI-GVNTQDDYAEDDEGGEDETNLINL-SRI------------------SKKFNENFKLNKKSLKFVSPVFQQFLDCVYQLLTQNPDLF
 .   ..          |.   .   .|    ..|||   .                   .  |..... .    .  ||.| |||| |.||  . |  |
sssssssssststtpsitkkssgsiskgssgiaslindldkydsnfvlpdtihtesqkkktylfqdqyessilvnrsfsPifvqfldlvwqlqkefPfhf

EFNERFLRRLVYHLYSCQYGTFLSNSEKEKFQQNLPNKTKSVWDYFRSRRKQFIN
|||| .|  || . .| ..|.|| .  |.. .... ...||.| . .  . .|||
efneslllllvkesfssrfGnflyseakrdserkvlkrsksiwsfinqnksrfin
0051429 (Phosphotyrosine protein) phosphatases II 367-416 4.4e-06 22.1 In-house 129-176 (272) alignment 
Range on Protein: 367-416
Range on HMM: 129-176/272.0
NWLKLN---TLILKSVDMLLKsiifnHSNVLVHCSDGWDRTSQVVSLLEICLD
.|.  .     .|. ...||.     . .|||||| |.|||  || || . |.
dwpdhgvpqeallellellld.....ggpvlvHCsaGkdRTGtvvallllllg
PTPc_DSPc_SM00012 385-421 2.2e-07 26.4 In-house 38-70 (105) alignment 
Range on Protein: 385-421
Range on HMM: 38-70/105.0
SiifnHSNVLVHCSDGWDRTSQVVSLLEICLDPFYRT
|    ...|.||||.|..|| ..| |  .. .  ..|
s....skpvvVhCsaGvgRtgtfvaldillqqleket
subfamily_MTMR6_pd Subfamily MTMR6 502-607 8.2e-32 102.9 In-house 270-375 (397) alignment 
Range on Protein: 502-607
Range on HMM: 270-375/397.0
SKKFNENFKLNKKSLKFVSPVFQQFLDCVYQLLTQNPDLFEFNERFLRRLVYHLYSCQYGTFLSNSEKEKFQQNLPNKTKSVWDYFRSRRKQFINPNFIQ
  ||.|   | ... | |||.|.|||.||.|||.| |  |||||||| .|  |.||||.||||.|.||.. ...| ..|||.| |. .|.....|| . .
GhkfsercGlldedskevsPiftqflecvwqlleqfpkafefnerfllelhdhvyscqfGtflgncekdrrdlklkertkslwayllerkddylnplyka

RKRSGM
......
etekev
subfamily_MTMR3_pd Subfamily MTMR3 512-602 1.1e-25 83.4 In-house 328-418 (442) alignment 
Range on Protein: 512-602
Range on HMM: 328-418/442.0
NKKSLKFVSPVFQQFLDCVYQLLTQNPDLFEFNERFLRRLVYHLYSCQYGTFLSNSEKEKFQQNLPNKTKSVWDYFRSRRKQFINPNFIQR
|..  .  .||| |.||.|.||  | | .||||| || .|| | ||| .|||| |||||. .... ..| |||...|.. |.. |  . ..
nvddanercPvflqwldavhqlqrqfPtsfefneaflvklvqhtysclfGtflansekereeekvkertlsvWsllrakekeyrnllykek
subfamily_MTMR9_pd Subfamily MTMR9 513-600 9.6e-26 82.7 In-house 278-367 (393) alignment 
Range on Protein: 513-600
Range on HMM: 278-367/393.0
KKSLKFVSPVFQQFLDCVYQLLTQNPDLFEFNERFLRRLVYHLYSCQYGTFLSNSEKEKFQQNLPNKTKSVWDYFRS--RRKQFINPNFI
... |. .|||  |||||||.|.| |  |||||..|  |  | ||.|.|||| ..|.|. ...| .||.|.|.|  .  ..|||.|| . 
etkkklsgpvfllFLDcvyqilsqfpasFEFneelLillfehsyssqfgtflcdneaerkelklkkktvslwsyvnrpeklkqflnplye
subfamily_MTMR1_pd Subfamily MTMR1 514-603 1.2e-28 92.5 In-house 273-362 (389) alignment 
Range on Protein: 514-603
Range on HMM: 273-362/389.0
KSLKFVSPVFQQFLDCVYQLLTQNPDLFEFNERFLRRLVYHLYSCQYGTFLSNSEKEKFQQNLPNKTKSVWDYFRSRRKQFINPNFIQRK
.| .  |||| ||.|||.||  | |  |||||.||  |. ||||| .|||| |||||. .... .|| |.| |. |....|.||.. . .
ssdaersPvFlqfiDcvwqltrqfptAFefneefLitlldhlysclfGtflfnsekervkekvkektvslwsyvnsskeeftnplyaeel
subfamily_MTMR5_pd Subfamily MTMR5 517-592 5.5e-19 60.3 In-house 359-445 (483) alignment 
Range on Protein: 517-592
Range on HMM: 359-445/483.0
K-FVSPVFQQFLDCVYQLLTQNPDLFEFNERFLRRLVYHLYSCQYGTFLSNSEKEKFQQNL--------PNK--TKSVWDYFRSRRK
.  ..||| ||||||.|. .| |  ||||. .|. | ||  |... ||| .||.|.....|        ..|  .||||||   . |
ssgfaPvFlqFLDcvhqvsrqfPlafefndfylkflayhsvsnrfrtfllDseyerlesgllyeekaekrakkagksvwdyidrqhk
subfamily_Ank-MTMR1_pd Subfamily Ank-MTMR1 519-600 6.4e-21 66.6 In-house 297-378 (405) alignment 
Range on Protein: 519-600
Range on HMM: 297-378/405.0
VSPVFQQFLDCVYQLLTQNPDLFEFNERFLRRLVYHLYSCQYGTFLSNSEKEKFQQNLPNKTKSVWDYFRSRRKQFINPNFI
 ||.|||||||..|||.| | ||||   .|  .   ..||.||||| | ||.. |...  || |.|   .   ..|.|| . 
rspifqqfldccfqllsqfpllfeftpslllfisdnihsckygtflnncekdrvqdqvktktisiwsevnlnvnkflnpyyn