Gene DCR2 in Saccharomyces cerevisiae

Synonym: CID1, DIS2, YER133W, GLC7

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPPL
Superfamily PPPL
Family PAP
Subfamily DCR2
Protein sequence
ID Type Fasta BLAST phosphatome Note
ScerP048_AA protein Get Run
ScerP048_AA_247-501 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
OapA_N Opacity-associated protein A N-terminal motif 3-24 3.4e-06 13.3 Pfam-A 5-26 (30) alignment 
Range on Protein: 3-24
Range on HMM: 5-26/30.0
RLPRLYQRYLLYLVVFVVIALF
.||.|..| |. |...|...|.
lLPklHrrllialsavvllLll
Metallophos Calcineurin-like phosphoesterase 248-501 9.7e-17 54.9 Pfam-A 1-199 (200) alignment 
Range on Protein: 248-501
Range on HMM: 1-199/200.0
FKIVQLADLHLGVGESEcideypkheackaDpkTETFVQQVLDIEKPQLVVFTGDQIMGDRSIQDSETVLLkAVAPVIARKIPWAMVWGNHDDEGSLTRW
..|....|||.|  ..|             |  ..  ....   |||.||.|.|| . ...     .  |    .. ....||.... |||.. .  ...
lrilvigDlHgglddle.............d..lllillkiaaeekpdlvlflGDlvdrgdwssetlalld.ylvlklllpipvfllrGNHesdpgnsay

QLSEIASVLPYSLFKFSPHDTHDntfgvgnyiyqifsnndtevpVgtlYFLDSHKYSTVGKIYPGYDWIKESQWKYIEDYHDVNLKFKTGLSMAFFHIPL
   .. . ... |.. . ...                       .   ..|  ... ..|.  ....  .. |..  | .   .|. ...  .. .|.||
gflleqlkdlrglangeeeyenl.....................k...itllttsgelyglsglypllgdsaqeeqleeflalplralvdgkilltHgpl

PEYLNIESKThpgeknpligmykegVTAPKYNSEGITTLDRLSVDVVSCGHDHC
 .... . ..                    .. . .  | .  ||.| .||.|.
sssggsgddi...............gselfgpdalekllekygvdlvlrGHtHk
Metallophos_2 Calcineurin-like phosphoesterase superfamily domain 249-504 1.3e-08 27.0 Pfam-A 2-123 (156) alignment 
Range on Protein: 249-504
Range on HMM: 2-123/156.0
KIVQLADLHLGVGESEcideypkheackadpktetfvQQVLDIEKPQLVVFTGDqimgdrSIQDsetvllKAVAPVIaRKIPWAMVWGNHDdegsltrwq
||. ..|||... . |                     . . ||....|... ||      ...       ..| . . ..||  .| ||||         
kiaiiSDlHgnldale.....................avledikevdlilhaGD......lvep......eevvell.edipvlavrGnhD.........

lS----------EiasvlpyslfkfsphdthdntfgvgnyiyqIFSNNDTEVPVGTLYFLDSHKYStvgkiypgydwikesqwkyiedyhdvnlkfktgl
                                           .. ....|.   ..........|                                  
.eaelpkelavel..............................llaaaaleiegdrvllvhgtpls..................................

smaffhiplpeylnieskthpgeknpligmykegvtAPKYNSEGITTLDRLSVDVVSCGHDHCNDY
                                      .. .|   .|.   .|.| .|| | . .
....................................vqsseeelaellkeagadlvflGHtHkpkv
PPP_5_Dcr2 250-569 1.5e-34 112.7 In-house 1-199 (199) alignment 
Range on Protein: 250-569
Range on HMM: 1-199/199.0
IVQLADLHLGVGESECIDEyPkhEAckADPKTetfvqqvlDiekpQLVVFTGDQIMGDRSiQDSETVLLKAVAPVIARkiPWAMVWGNHDDEgsltrwQL
.....|||........|.. .  |.  .||..        .    .|.||.||....... ......||.|...|...  ......|||.||      ||
vtvcGDlHGqlddlllilf.k..eg..gdpse........e....rlyvFlGDyVDrGkd.slevlllLlalklvypk..evhllrGNHEde......ql

SEIASVLPYSLfkfSPHdthdntfgVGNYIYQIFSNNDTEVPVgtLYFLDSHKYSTVGKIYPgydWIKeSqwkyIEDYHDVNLKFKTglsmaffhiplPE
.||.......|   |..         |..||.|.|......|.  ....|.......|...|   .|| |    ||...... |...           ||
neiygftkevl...sky........hgkkiykilsdvfdwlPl..aalidekvlvvhgglsp...eik.s....iellekierkiei...........pe

ylniesktHPGEKNPLIgmykegvtapkynsegittldrlsvdV----VscghDHCNDYclrddstpnkiWLCYgggggeggyagyggteRRIRIYeInV
        ..|||..|.                          .    .    |.....           .|.                  |.... . .
........ekgekadll..........................lwsdpr....daqegc...........klns................eRGagl.l.f

NENNIHTWKRLNGSPKEIFDFQSM
.......... |.....|......
gpdvtekfleknnlkliirshelk