Gene INP52 in Saccharomyces cerevisiae

Synonym: SJL2, YNL106C, INP52

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family Sac
Subfamily Synaptojanin
Protein sequence
ID Type Fasta BLAST phosphatome Note
ScerP059_AA protein Get Run
ScerP059_AA_240-555 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
Sac_COG5329 1-1109 0.0 1680.5 In-house 1-1070 (1070) alignment 
Range on Protein: 1-1109
Range on HMM: 1-1070/1070.0
MKILLSKQQTRKIAIVSETHGLVFRPINSKNSRRSTCAVELVPKAELNGNGFRRLSN-HEIYGFIGLIEIEGLMFIATITGKSKVAQPIPNKTVNKIYAV
||||||...||.|||||....||||....|||..|.||.|||...||...|||.||. |||||..||||.||..|...|||||||||.||..|..||.||
MkillsekktRsiaivsnkyalvfrrlsvknselsvcaaelvavselkkegfrslssaheiygvlGlielegslflivitgkskvaqvipgetiykilav

DFFCLNNSKWDFMDIDSsgypivtndgdfaisspPSISTHSSRSSlrssssrslnaqeqapkHPCHELRKLLSNGSFYYSTDFDLTCTLQKRGFTEHSLS
||..|||.|||...|.|                 ...||...||.                 |||.||.|||||||||.|||||.|.|||||...|..||
dfislnnnkwddeeies.................deasteklrse.................hpcselkkLlsngsFYfStdfditntLqkrlkeelels

FDDFDREFMWNSFLMDEIITYRDRLDVTAKELLDQRGFLTTVIRGFAETIFSYINRLKVGLTIISRQSWKRAGTRFNARGIDDDGHVANFVETEMIMYSS
.|..|.||||||||..|.|.||..|....|.|||..|||||||||||||.|.........||.|||.|.|||||||.|||.||||.||||||||.|.|||
vdtadeefmwnsflleelinyrsklsslekqlldnagFlttvIrGFaetvfikvkkktiaLtlISRrSskragtRflarGvDddGnvanFVETEqIvyss

QYCYAFTQIRGSLPIFWEQ-DTSLISPKIQITRSVEATQPTFDEHFIRLFKKYGPVHIINLLSTKSSEIQLSRRYKEQLKNSEKMKIgrdvFLTSFDFHR
|||..|||.|||.|||||| ..|||.||||||||.||||..||.||..||.|||.|||.|||.||||||.||.||...||.|||.||    .||.||||.
qycfsFtQvRGSiPiFWeqesnsligpkiqitrsseatqsafdkHFdklfekYGdvhivNLlktKssEieLseryekhlklsekpki....hlteFdfhk

ETSQDGFAAASRIIPKIRNTILDAGYFSYDVKEGRLISEQDGVFRTNCLDCLDRTNLIQQTISLavfKLFLEDFRLVKPSSFIDDNEFVQKVNALWADNG
|||||||.......|.|....|..||||||||||.|||||||||||||||||||||.|||.||.   ...||.||..|..|.|||..|.||.|.||||||
etsqdgfddvkkLlplieqdllefgyfsydvkegkliseQdGVfRtNClDCLDRTNviQqlisk...rvlleqfrsikvisaiddedflqklneLWadnG

DQISQIYTGTNALKSSYSRKGKMSFSGALSDATKSVSRMYINNFVDKGKQQNIDTLLGKLPHQQVVELYDPICEYVNERLLESEEKFTTHSNINLFVGTF
|.||||||||.|||||..||||.|..|||||||||||||||||||||.||..||.||||||.|..|||||||.||||.|| .||..||...|...|..||
DaisqiYTGtgalkssftrkgkrsiagalsDatkSvsRmyinnfvDkekQdaidllLgklpdqeavelydpineyvnlrlrkseseftaaknvsiftltf

NVNGNSRRADLSKWLFPIGDKFKPDVVVLGLQEVIELTAGSILNADYTKSSFWETMVTDCLNQYEEKYLLLRVEQMSSLLILFFARSDRAYNIKEVGGST
|.||.|....|.|.|.....|.....||.. ..........||....|||.|.|.........||.|..  ..||.|| |...|........||||..|.
nsngessstkllklllkvlekkisklvvgvvglqkqiwlelillssltksefkeeeeenlvrkyenklkkkkleqsssqltalfilfkksadikevvsse

KKTGFGGITGNKGAVAIRFDYGATSFCFVNTHLSAGASNIDERRNDYNNIYRNITFPRSKTIPHHDSLFWLGDLNYRITLTNDEVRRELRAQKDGYIDRL
|..|....||...|........|.|...|.....|.|...||.....|..|..||...||.||.... ..|..|...|.||.|....|.||.|...|||.
kaagrktgtgglnankgavkieaeseglvfifvdasaaledenesernskyesitkrvskeipkmikdhqlilldiainltidydeeevraekekeidre

LQYDQLTQEINEGVVFQGFKEPTLQFRPTYKYDYGTDNYDTSEKARTPSWTDRIIYKGENLHPLAYSDAPLKISDHKPVYAAYRANVKFVDEKEKLNLVE
|.... .||..|.|......||| ......|..|..||....|.|.....|...|.|.|....||||...|||||||||.|.....|...|||.||.|..
lkkydtkqeltekvfvekvleptevpellekksyeddndtdtedayrklrtrkliqkeekktelaysslelkisdhkpvtaevkiavlskdekkklklel

KLYAEYKNTHPEALTTGPDELSHARMEKQKESIPLDATVQSAGIKLIDLDDTSSCVSPLLSGPSPQPSVVGPGGLSNVSPDKSKLNVLPPPPPTSRHNKE
.|...||...|..|...|||||.|...|..|.|.||||.||...||.|||||......|.|..|.|||..........|..||||||.|..|.||..|||
slkiayktekpselpeepdelssallskdlekisldatkqskvvklvdlddtmaqpkalpsksseqpsepeaslrpsrsqnksklnvepkkpstskqnke

PSSKLLSPTKEISIVSVSPRKGESNLPALERHSTPKPLPPVPALSLSKPVSLQKSSSELQHAKETIDNGKIVPRPCPPIRRKSSTAPDEISTSTKNSGVS
..|.||||..|||.||.|.|||.|...|.|..|.||..|.|..|||||||||||..|.....||.|||.|.|.|...|||||||.|..|.|||||....|
kkssllspipeiSkvssslrkgssaslasetksipkkkpkvtklslskpvslqkllspkstskeaidnakkvdrvnspirrksskadaeqststklaass

TTEDPEPAKAS
.|||.|.||.|
etedqeeakls
subfamily_INPP5F_pd Subfamily INPP5F 2-999 0.0 1541.2 In-house 9-951 (951) alignment 
Range on Protein: 2-999
Range on HMM: 9-951/951.0
KILLSKQQTRKIAIVSETHGLVFRPINSKNSRRSTCAVELVPKAELNGNGFRRLSNHEIYGFIGLIEIEGLMFIATITGKSKVaqpipnktvnkiyavdf
||||.....||..||||.. |...|...|.|.....|.|.|.|..|. .....|...|..|.|||||.|| ...|||.|||||                 
killvseeerkLvivsessilgllpvqkkeskkevvaiervakldlsekdskelekeectgliglielegkiivatiegkskv.................

fclNNSKWDFMDIDSSGYpivtndgdfaissppsisthssrssLRSSSSRSLNAQEQAPKHPCHELRKLLSNGSFYYSTDFDLTCTLQKRGFTEHSLSFD
   ||.|||..|||||||                         |....... |..|...|....||.||||.||||||.|||||.||||||..|.| |.|
...nnkkwdlididssgy.........................lqlkeekeqneeeklekrlleelkkllsdgsFYysldfDltntlqkrgleeksestd

DFDREFMWNSFLMDEIITYRDRLDVTakelldqrgFLTTVIRGFAETIFSYINRLKVGLTIISRQSWKRAGTRFNARGIDDDGHVANFVETEMIMYSSQY
|.|..|.||.||....|.|||.||..         |||.||.||.|| ...|..||| ||.|||.|.|||||||..|||||||.||||||||.|.....|
dwderFfWNkfllkdlinyrdkldke.........fltpviqGfvetkeisieklkvsltlisrrSrkragtrfkrrGidddgnvAnfvEtElilsveky

CYAFTQIRGSLPIFWEQDTSLISPKIQITRSVEATQPTFDEHFIRLFKKYGPVHIINLLSTKSSEIQLSRRYKEQLKNSEkmkiGRDVFLTSFDFHRETS
...|||||||.|.||||......|||.||||.|.|||.||||| ...||||.|.|.||||.||||..||..|||||...|     .||||..||||.|||
vlsftqirGSvPvfweqsgkkykpkikitrseeetqpaFdehfkeqlkkygkvvivnllsqkssekklskaykeqllkle....skdvflikfdfheets

QDGFAAASRIIPKIRNTILDAGYFSYDVKEgRLISEQDGVFRTNCLDCLDRTNLIQQTISLAVFKLFLEDFRLVKPSSFIDDNEFVQKVNALWADNGDQI
...|...|..|..|.|.|...||||||||| ..||||.|||||||||||||||..||.||.||..|.||...|..|.|.|||.|..||...|||||||.|
gekfenvsklielikneikevgyfsydvke.kviseqkgvfRtnclDcldrtNvvqqaiskavlelqleklglfepessiddeellqklkklWadngdai

SQIYTGTNALKSSYSRKGKMSFSGALSDATKSVSRMYINNFVDKGKQQNIDTLLGKLPHQQVVELYDPICEYVNERLLESEEKFTTHSNINLFVGTFNVN
|..|.||||||....|||.....|.|.|..|||||.|.|||.||..|..||.||||||.|.||||.||..|...|.|.|.|||||..|||||.||..|||
srqYagtnalkgdltrkgerklaGvlkdgyksvsryylnnfkdkyrqkvidlllGklpkqevvelidpkkeekeeelrekeekftetsninllvgsvnvn

GNSRRADLSKWLFPIGDKFKPDVVVLGLQEVIELTAGSILNADYTKSSFWETMVTDCLNQY--EEKYLLLRVEQMSSLLILFFARSDRAYNIKEVGGSTK
|.|..|||||.|||||.|||||.||||||||.||||||||.|||.||.|||..|.|.||..  |||||.||.||.||||.|.|.|.|.|...|||.|.||
gsskkadlskllfpigekfkpDlvvlGLqEvvELtaGsiLaaDyskskfWEklvedlLnkvsreekYlkLrseqlsslLlllfvredkakkvkevegdtk

KTGFGGITGNKGAVAIRFDYGATSFCFVNTHLSAGASNIDERRNDYNNIYRNITFPRSKTIPHHDSLFWLGDLNYRITLTNDEVRRELRAQKdgyIDRLL
||||||..|||||||.||.|.||||||||.||.|||||..|||.||..|.|.|||.|||.|..|||.||||||||||.|.|.||||||..|.   ||.||
ktGfgGlagnkGavavrfeysatsFcfvnsHlaAGasnveeRrsDykeiarsitFsrskrikdhDsifWlGDlnyRidlpneevRRelldqe...idkLl

QYDQLTQEINEGVVFQGFKEPTLQFRPTYKYDYGTDNYDTSEKARTPSWTDRIIYKGENLHPLA-YSDAPLKISDHKPVYAAYRANVKFVDEKEKLNLVE
.|||||.||..|.||.||||.||.||||||||.||.|||||||.|||.||||||||||.|..|. ||||...||||.|||||.||.|..||||.||.|..
eyDqLtkeieaGevFegfkEetlkFrPtYkyDlgtknYDtsekeRtPaWtDRiiykgevledLeyysdaeilisDHrPvyaafrakvtvvDekkkltLkk

KLYAEYKNTHPEALTTGPDELSHARMEKQKESIPLDATVQSAGIKLIDLD-----DTSSCVSPLLSGPSPQPSVVGPGGLSNVSPDKSKLnVLPPPPPTS
|||.|||....|| ....|||.....||..|...||..|.||..||.|||     |.||.||.||||...|..||.......|||||.|. |.||.|...
klyeeykeeleeasdsekdellsddlekkeeaesldkivesaelklldldpkraqdssssvskllsgsakqvkvvldvdsasvspdkkkv.vrppepeae

RHNKEP
...|||
klvkep
Syja_N SacI homology domain 60-405 1.4e-96 314.4 Pfam-A 1-317 (319) alignment 
Range on Protein: 60-405
Range on HMM: 1-317/319.0
IYGFIGLIEIEGLMFIATITGKSKVAQPIPNKTVNKIYAVDFFCLNNSKWDFMDIDssgypivtndgdfaissppsiSthssrsslrssssrSLNAQEQA
.||..|||...   ..  ||...|||.. ..... ||  |.|..||.....   |.                     .              . . .|..
aygilGlirllsesyllvitkrekvakirgehpiykiksvefiplnseeeessaie.....................e..............ekeeeeke

PKHPCHELRKLLSNGSFYYSTDFDLTCTLQKRGFTEHS---------LSFDDFDREFMWNSFLMDEIITYRdrldvtakelLDQRGFLTTVIRGFAETIF
 ......|.||||.||||.|.|.||| .||..  .|..           ....|..|.||..|....|...          ||.  .|...|.||.|.  
eekllkllkkllssgsfYfSydyDltrslqrksekeeeekeeeskslpllkevderFvWNrnllkplielk..........ldlsrwllpliqGfveqrs

SYIN-RLKVGLTIISRQSWKRAGTRFNARGIDDDGHVANFVETEMIMY-S---SQYCYAFTQIRGSLPIFWEQ-DTSLISPKIQITRSVEATQPTFDEHF
 ...   || ||.|||.|.||||||...|||||||.||||||||.|.. .   |.....|.||||| |.||||  .  ..|||.|||| ||.|..|..||
ievkskkkveltLIsRrsvkraGtRylrRGidddGnvANfvEtEqivsekkeeskrvfSfvqiRGSvPlfWeqasnlslkpkikitrsseasqkafkkHf

IRLFKKYGPVHIINLLSTKSSEIQLSRRYKEQLKNS-EKMKIGRDVFLTSFDFHRETSQDGF
 .|.|.||.....|||..|..| .||..|.|....  .|.|  ... ...||||.|... .|
kklikrYgkivvvnLlekkgrEkkLseayeelinklnkklkekkklkyiefDfhkeckgkkf
Syja_N SacI homology domain 60-405 1.4e-96 314.4 In-house 1-317 (319) alignment 
Range on Protein: 60-405
Range on HMM: 1-317/319.0
IYGFIGLIEIEGLMFIATITGKSKVAQPIPNKTVNKIYAVDFFCLNNSKWDFMDIDssgypivtndgdfaissppsiSthssrsslrssssrSLNAQEQA
.||..|||...   ..  ||...|||.. ..... ||  |.|..||.....   |.                     .              . . .|..
aygilGlirllsesyllvitkrekvakirgehpiykiksvefiplnseeeessaie.....................e..............ekeeeeke

PKHPCHELRKLLSNGSFYYSTDFDLTCTLQKRGFTEHS---------LSFDDFDREFMWNSFLMDEIITYRdrldvtakelLDQRGFLTTVIRGFAETIF
 ......|.||||.||||.|.|.||| .||..  .|..           ....|..|.||..|....|...          ||.  .|...|.||.|.  
eekllkllkkllssgsfYfSydyDltrslqrksekeeeekeeeskslpllkevderFvWNrnllkplielk..........ldlsrwllpliqGfveqrs

SYIN-RLKVGLTIISRQSWKRAGTRFNARGIDDDGHVANFVETEMIMY-S---SQYCYAFTQIRGSLPIFWEQ-DTSLISPKIQITRSVEATQPTFDEHF
 ...   || ||.|||.|.||||||...|||||||.||||||||.|.. .   |.....|.||||| |.||||  .  ..|||.|||| ||.|..|..||
ievkskkkveltLIsRrsvkraGtRylrRGidddGnvANfvEtEqivsekkeeskrvfSfvqiRGSvPlfWeqasnlslkpkikitrsseasqkafkkHf

IRLFKKYGPVHIINLLSTKSSEIQLSRRYKEQLKNS-EKMKIGRDVFLTSFDFHRETSQDGF
 .|.|.||.....|||..|..| .||..|.|....  .|.|  ... ...||||.|... .|
kklikrYgkivvvnLlekkgrEkkLseayeelinklnkklkekkklkyiefDfhkeckgkkf
subfamily_SAC1_pd Subfamily SAC1 151-558 1.9e-102 334.3 In-house 55-453 (458) alignment 
Range on Protein: 151-558
Range on HMM: 55-453/458.0
RSLNA-QEQAPKHPCHELRKLLSNGSFYYSTDFDLTCTLQKRG-----FTEHSLSFDDFDREFMWNSFLMDEIITyRDRLDVtakelldqrgFLTTVIRG
.||   |... |.  . |...|.. .||.|...||| .||..      ..... ... .|. |.||. |.... . ...|.           |.  ||.|
lslteeqkkeekeylkllelvlksetfYfsytydltnslqrlekvtsaalkerslleradeRffwnkhlledlrk.epeles..........filPvikG

FAETIFSYINRLKVGLTIISRQSWKRAGTRFNARGIDDDGHVANFVETEMIMYSSQYCYAFTQIRGSLPIFWEQDTSL-ISPKIQITrSVEATQPTFDEH
|...    .|. .. ...||| | .|||||.. ||.| .|.|||||||| |.  ..   .| |.|||.|..|.|  .| . ||.... . | .. .|..|
fikikelslnakeikfilisRRsifRaGtRyfvRGvdkeGnvanfvEtEqiveaekaltsFvqvRGsiPllWsqkpnLkykPkvkls.esedsldafkkh

FIRLFKKYGPVHIINLLSTKSSEIQLSRRYKEQLKNSEKMKIGrdvfLTSFDFHRETSQDGFAAASRIIPKIRNTILDAGYFSYdVKEGRLISEQDGVFR
. .. ..||.  ..||.  | || .|  .|.. .....| ||      ..||||.| ..  .   . .| .....  . |||.   .|.....|| ||.|
ldeqielygenvlvnLvdqkGsEkklgeayesvvralnkkkik....yvafDFHkeCrkmrwdrlklLidqlekelsqegyflk.seekkivkeqkgvvR

TNCLDCLDRTNLIQQTISLAVFKLFLEDFRLVKPSSFIDD-NEFVQKVNALWADNGDQISQIYTGTNALKSSYSRKGKMSFSGALSDATKSVSRMYINNF
|||.|||||||..|  ..  | .  || . ...  | ..| .|. ..   |||||.|..|. |.|| |||. . |.|| ...||| | ..|||| |.|||
tnCiDcLDRtnvvqsllarevLqkqleslgvlateskledsaeletsfknlwadnadavsvqYaGtgAlKtDftRtGkrtllGalrDgvnsvsryyknnf

VDKGKQQNIDTLLGKL
.|. .|. || .|||.
ldgerqdsidLflgky
subfamily_Synaptojanin_pd Subfamily Synaptojanin 162-856 1e-173 570.7 In-house 61-751 (754) alignment 
Range on Protein: 162-856
Range on HMM: 61-751/754.0
HPCHELRKLLSNGSFYYSTDFDLTCTLQKRGFTEHSLSFDDFDREFMWNSFLMdeiiTYRDRLDVTAKElldqrgFLTTVIRGFAETIFSYINRLKVGLT
.   ||.|||. |.||.|.  | . .|.    .... . .  |  |.||  |     ..  | .| ...      .|. |..|  |    |.   ..  .
driielkkllasgtfyfsssadsasrldlslsaqrrkqeesednrffWnrslh....lhlqrfgvncdd......WllkvmcGsveirtvyagakqakaa

IISRQSWKRAGTRFNARGIDDDGHVANFVETEMIMYSSQYCYAFTQIRGSLPIFWEQDT-SLISPKIQITRSVEATQPTFDEHFIRLFKKYGPVHIINLL
.||| | .||||||| ||..|.|.|||||||| ...  .   .| |||||.|.||||      | |....|..||....|| |.  | ..|| | |.|||
lisrlsceraGtrfnvrGvndeGnvanfveteqvillddkvtsfvqirGsvPlfWeqPGlqvGshkvklsrgfeasaaafdrhleqlkeryGevvivnll

STKSSEIQLSRRYKEQLKNSEKmkiGRDVFLTSFDFHRETSQDGFAAASRIIPKIRNT-ILDAGYFSydVKEGRLISEQDGVFRTNCLDCLDRTNLIQQT
 .| .|  ||. .|..||.||     .||   .||.|... ..  .. .... |. .. . .|..|.   |.... .|| || |.|||||||||| .| .
Gskegeevlskafkkhlkaseh...akdvpfvkfdyhqkvkggkkeklekllkkqlklflesasffl..skgkevekeqtGvlrvnClDCldrtnavqtv

ISLAVFKLFLEDFRLVKPSSFIddNEFVQKVNALWADNGDQISQIYTGTNALKSSySRkgkmsfSGALSDATKSVSRMYINNFVDKGKQQNIDTLL-GK-
..|.| .  || ..| . .| .  ..| .  ..||  |||.||.||.|| ||... ..      .. | |...||.|   |||.|  ||. || || |. 
lglevlekqlealklsskesvv..srfeevfkslWsknGdeiskiyaGtgalegk.ak......vsklkdgarsvartiqnnfldsskqeaidllllgnt

----LPHQQVVELYDPIC---EYVNERLLESEEKFTTHSNINLFVGTFNVNGNS-------RRADLSKWLFPIGDK------FKPDVVVLGLQEVIELTA
    | ..    |.         . ..| | |...|. ... ..|||.||||         ... |..||. . ..         |.. .|..|...|.|
yveeladkarallkssllrasakilkelvereqelteakklricvgtwnvnggkqlrsvalknesltdwlldlpelsgaedskpadiyaiGfeelvdlna

GSILNADYTKSSFWETMVTDCLNQyEEKYLLLRVEQMSSLLILFFARSDRAYNIKEVGGSTKKTGFGGITGNKGAVAIRFDYGATSFCFVNTHLSAGASN
. ...|  |.   | . ..  | . ..|| ||  ||.  . .  |.|.. .  |..|. || |||.|| .|||||||||.   .||.||. .||.|| |.
snlvsasttnrkewaeelqkvlsr.dakyvlltseqlvGvclfvfvrpklvpfirdvavstvktGlgGaaGnkGavairlllhstslCfiCshlaagqsk

IDERRNDYNNIYRNITFPRSKTIPHHDSLFWLGDLNYRITLTNDEVRRELRAQKdgyIDRLLQYDQLTQEINEGVVFQGFKEPTLQFRPTYKYDYGTDNY
. || .||..|.| |.|| ..|.  || .|||||.|||| |..|||.. .. ..    |.|.. ||||.. ..| ||.||.|..|.| ||||||  .|.|
vkernedyaeiarkiafpmgrtleshdyvfWlGdfnyridlekdevkelvkkkd...ydklvendqltkqkkkgkvfkgfaegeltfaPtykydlfsddy

DTSEKARTPSWTDRIIYKG
||||| |.|.||||.... 
dtseklrvPaWtdrvlwrr
subfamily_FIG4_pd Subfamily FIG4 174-566 5.8e-62 200.8 In-house 140-550 (569) alignment 
Range on Protein: 174-566
Range on HMM: 140-550/569.0
GSFYYSTDFDLTCTLQKRGF-----TEHSLSFDDFDREFMWNSFLMDEIITYRDRLDVTAKELLDQRGFLTTVIRGFAETIFSYINRLKVGLTIISRQSW
  ||.|  .||| |||.        .|.. . |  |..   .   ..|  .. . |  . |. ...  .| ..| || .     .   .. .|.|.|.| 
knfyfsysydltrtlqtnlllsdsnrekekaedrvditieakkldanekfvWnnflleplkdtvktfdWlleiihGfvsqskisvlgksiyvtliarrss

KRAGTRFNARGIDDDGHVANFVETEMIM-------YSSQYCYAFTQIRGSLPIFWEQDTSLISPKIQITR-SVEATQPTFDEHFIRLFKKYG-PVHIINL
| ||.||  ||.. .|.||| |||| |.       ..|.   .|.|.|||.|..|.||.| . .| .|.   |.    .   || .||..|| |. |.||
kfaGarflkrGvnnkGdvaneveteqivheasegsldsdryssfvqlrGsvPlyWsqdasklvtkPpikidvvdPfasaaalhfddlfqryGspiiilnl

LSTK---SSEIQLSRRYKEQLKNSEKMK-IGRDVFLTSFDFHRETSQDGFAAASRIIPKIRNTILDAGYFSyDVKEGRLISEQDGVFRTNCLDCLDRTNL
. .|     | .|.. ... ..   ..    . .  .|.|..| . ...    . .    ....   |.|  . .. .    | |. ||||.||||||| 
vkkkekrkresilleefeaaieylneflPeekklkyiswdmaraskskeenvlevlekyaeksvkktGifl.sapdlestkiqeGivrtnCvdcldrtna

IQQTISLAVFKLFLEDFRLVKPSSFIDDNEFVQKVNALWADNGDQISQIYTGTNALKSSYSRKGKMSFSGALSDATKSVSRMYINNFVDKGKQQNIDTLL
 |  |.   ..  |... ... |..  | . |. .. |. | ||...  |.|..  ..  . .   ..|   .|  ....| | | |||. ||. |. .|
aqfvigkvalgyqlkslGiidesklefdsdvvrlleelyedlGdtlalqygGsqlvntiktyrkiaqwssksrdiletlkryysnsfvdadkqdainlfl

GKLPHQ-QVVEL
|.   . .. .|
Gvyspreglpsl
Exo_endo_phos Endonuclease/Exonuclease/phosphatase family 596-874 5.5e-29 91.7 Pfam-A 1-249 (249) alignment 
Range on Protein: 596-874
Range on HMM: 1-249/249.0
GTFNVNG-------NSRRADLSKWLFPIGdkfkPDVVVlgLQEVIELtagsilnadytkssfwetmvtdclnQYEEKY----------------------
.|.||.|       ......| ..|  ..    |||..  |||| |                          .. |..                      
ltwNvlgwnarsdrakkldqladllqsed....pDvll..LQEvded.........................plsellatglaselgldgdgksgggggg

-LllrveqmSSLLILFFARSDRAYNIKEVGGSTKKTGFG---GITGNKGAVAIRFDygATSFCFVNTHLSAGASNID--ERrNDYNNIYRNITFPRSKti
 .           . .... . .  |. .  .. |.| .   ...||||.|..||    .....|||||..| .. .  ||  ... | .  ...|..  
da.......gggglallskypldkkirrtfqldgkagiavprlssgnkgdvpvrfr..gktlalvntHltpgnrlrqrder.allaeidkladdsrgs..

phhdSLFWLGDLNYRITLTNdevrrelraqkdgyidrllqydqltqeinegvvfQGFKEPTLQFRPTYKYDYGTDNY-------------DTSEKARTPS
    .....||.|.|. ...                                  .|| |.   |.|....| |....             ||.||||.|.
....pvilaGDfNsrpdspd..................................kgfresaadflpgdgfddglrallphlllptspgttdtyekarepa

WTDRIIY-KGENLHPLAYSDAPLKI--SDH
..|.|.. .|.  . . ....   .  |||
rlDyilvssgwpalvvsgasllsdrggSDH