Gene MTMR5-2 in Strongylocentrotus purpuratus

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family Myotubularin
Subfamily MTMR5
Protein sequence
ID Type Fasta BLAST phosphatome Note
SpurP035_AA protein Get Run
SpurP035_AA_1062-1615 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
uDENN uDENN domain 78-119 4.2e-11 32.1 Pfam-A 22-64 (65) alignment
Range on Protein: 78-119
Range on HMM: 22-64/65.0
YMQSFCQPAGWRITSKA-QPPTYHVSVLTDIEARRHYCAVLTF
..  ||.| |....... |.|.... ||||..  |.|.. |.|
aipmFCfPeglnfvtsreqkpeffsfvLTdedgsriyGfClrf

DENN DENN (AEX-3) domain 150-331 1.2e-57 184.1 Pfam-A 2-184 (185) alignment
Range on Protein: 150-331
Range on HMM: 2-184/185.0
APKCLALISRLEYFETLKNCLGLMYTVYVDNVEVEMETLVGNILGHVQVPPPGGPQVRFSIGAGDRQALQPPLSDSLPVSRSSVALLVQQLGIHNIITLF
.||.| ..|||..||..|..|  ..... .. ....|... |.| .|..|.|| ... .| .. ... || | |..||.. ...  | ..|.|.|...||
ipkalcilsrlpffelfkkiLkalekrlksssklplesfianlllevplPapgktlklkslsvkekillqrpssselPledvdleelfrcLsienvlqlf

CAAVTDQKIMFHCRSYTRLTEACGALISLLFPLKYSYVYIPVLPAALIEVLSTPTPFIMGIHSALKE-EATELLDVIVADLDG
.|......|... ....|||... || .||.|||....|||||||.|..||..|||||.|..|.|.| | ..| ||...||| 
eavLlErriillSeklarLtsvaealvallyPlkWqhiyiPvlpaslldvleaPtPfiiGvesslleleekpledvvlvDldt

SPA Stabilization of polarity axis 242-330 2.5e-06 14.6 Pfam-A 12-105 (113) alignment
Range on Protein: 242-330
Range on HMM: 12-105/113.0
IHNIITLFCAAVTDQKIMFHCRSYTR--LTEACGALISLLFP---LK-YSYVYIPVLPAALIEVLSTPTPFIMGIHSALKEEATELLDVIVaDLD
....|.|. | .|...|.. ... .   . |.. || .|  |   |. ... ..| .    .. |.  . .|.|.  .. || .|. ||.. |||
tpkvillinalltqkriivlsteasadevcefvLalcllvspgavlrgfknnsfPyvdlskldklekvpgyIaGvtNPiFeeqeewWDvlc.dld

SBF2 Myotubularin protein 467-707 3.2e-82 264.5 Pfam-A 9-225 (225) alignment
Range on Protein: 467-707
Range on HMM: 9-225/225.0
NFEGHRNLVNNSARRLEVLRTCINFIFENKILDARRLFPAVMRSLKSRVARQALLHELELHVNKNRAMLEPQQFSMVVRLINAALQEDSHSEEFSLSMDF
 .| ... |.||||||||||.||..||.||||.|....|||.|.|||. ||.|| .|||.||..|||.|. ||| .||||.|.|||.||...| ..   .
ivektkstvensarrlEvlrnCisyiFdnkileakKslpAvlralkskaaRlalceelekhvqqnravLdhqqFDlvvrlmNkaLqddsakdeygvaaal

LPLISAFCRKLCPGIIQFAYTVTQDHPVFASHAFWETAFYADVEKNIQSLYVTpdntptyekkdvsqsfndafaaapDASGSSASSAAANGLITSAERSP
||| |||||||..|..|||||. |||||.... |||..|| .|.|.|..|| .                        . | |. ..  .. |....|.| 
lplssafcRKLsegvsqfaYtcvqdHpvWknqqFWeatfyqevqkaikelyle........................kkseskkkkktesslskkeeksa

LDIAAEQLRLQPNMNHDAREEAKSNEESIVYSQAVHYANRM
|.|||.|||..|..... ..|  ..||| |||||.|.|||.
leiaadqlrkwptlskekqkelvkkeestvysqaihfanrl

GRAM GRAM domain 801-882 4e-11 33.7 Pfam-A 5-68 (69) alignment
Range on Protein: 801-882
Range on HMM: 5-68/69.0
KPTFLPGEEKVMEGLRGYLVLDgreegqggvmggptLLPAEGAVFLTTYRIIFKGTPIDMQAceqvVTRSFPVSALVKEKKI
|.  ||.|||. . .. ||  .              ..|..|...||.||.||.. . | ..    |....|.... . .|.
ktfklppeEkllddyaCylsts..............kgpvqGrlYlTnyrliFrSdklddsk....vvvvipladikrveks

0040695 (Phosphotyrosine protein) phosphatases II 1060-1611 1.3e-102 337.3 In-house 4-384 (388) alignment
Range on Protein: 1060-1611
Range on HMM: 4-384/388.0
TVEKLAERQYVQDYTRLGLGLlgngaisrprvgDMFKISEVNSKFEVSRSYPALIVVPSVLSDDSIRRLAKCHRHGRLPAITWRHQRTKGLLIRSSGFHG
..|   .. ......||||||            |...|| ||...|...|||||.|||. .||. ..| |.. ..||.|....||.... .|.||| ...
leegwslydilrelkrlglgl............dlwrisivNenyelcpsYPallvVPksisdellkrvarfrskgriPvlsyrhpnngavllRssqplv

kgvmgmiksaqtqgsstseSSGSSKSLEQEKYLSAIVLNTPygsahksdslvslnsilpptnsgetpdgtptisprkgthgtgtllqrgflrssggqkay
                   .   |.|||.||.|.||.  .|                                                           
...................glllsrsledeklleailkllp...........................................................

tgkpgntlkgggrlmmgasghtqlgggvspaiskkhltlgsrtsatrngsvteqDLAMPRKQEARKAALYVFGEKSQLRNFKSDQNSKCDFIPYDYYETR
                                                      .| .    ..|. . ...   .     . |  .....|.... . .
......................................................nlskllivdlrpklnalanralgggvenedaypnaeliflnipnih

HIKASFKKLMKACLPSNPMTdpemGFHKMVGESEWLLQIQNIMQLAGAAVDLIDLQGSSVWLSFEDGWDFTTQVSALAQLLMDPYYRTLAGFKVLVDKEW
....|..||..|||.. ...     ......||.|| .|..|..||  .|.|.||..||| .  .|||| |.|.|.|||||.||||||| || ||. |||
vvreslqklldaclnvpdsl....nllslleesgwldliklilelavlivklldlgnssvlvhcsdgwdrtsqlssLaqllldPyYRTleGFqvLiekeW

LAFGHRFTHRTNQTI-THQTSGFAPVFLQFLDCVHQVHSQFPLSFEFNQYFLKTIAYHYVSNRFQTFMWDSDYERYQAATqvyeerrpsridesgdsdse
|.|||.| .|....  ......|.||||.|||||.|.. |||..||||...|...|.|..|.|| ||...|..||... .                    
lsfghkfadRlghleseidskefsPvFllFLdcvwqLlrqfPtaFeFnerlLlfLadhlyscrfgtFlfnsekerlelsv....................

tpSPPLKSLWDYMDKYHPRspiFYNFQFAPHTT-VLRPYTNTSSLIIWDYFLKE
  |  . |||.|.  .. .   |.|. . |... ||.|... ..|..|... ..
..sertlslwsyllsrkse...flnplYdpsslevllpslsvldlllWleyylr

subfamily_MTMR5_pd Subfamily MTMR5 1061-1613 1.8e-230 757.7 In-house 2-483 (483) alignment
Range on Protein: 1061-1613
Range on HMM: 2-483/483.0
VEKLAERQYVQDYTRLGLGLLgNGAisrPRVGDmFKISEVNSKFEVSRSYPALIVVPSVLSDDSIRRLAKCHRHGRLPAITWRHQRTKGLLIRSSGFHGK
|||||||.|||||.|||||.| |||   ...|. |.|||||.|..|.||||||||||| .|||||.|.|||.|..|||..||||.|.|.|||||.||..|
veklaerayvqdykRlGlgal.nga...skrgk.frisevNkkytvcrsYPalivvPsevsddsiarvakcfrqnRlPvvtWrhernkalLiRsggfesk

GVMGMIKSAQTQGSSTSESSGSSKSLEQEKYLSAIVLNTPYGSAHKSDslVSLNSILPPTNSGETPDGTPTISPRkgthgtgtllqRGFLRSSGGQKAYT
||.|..|||.||||||||||.|||||||||||.|.| .... ||....  .||...|. ..| ...| ....|..           ...|..| ..||..
gvvgllksantqgsstsessessksleqekylkavvnevsklsalaln..sslevslsvlasssssdkraalste...........knaldisksdkasq

GKPGNTLKgggrlmmgasghtqlgggvspaiskkhltlgsrtsatrngsvtEQDLAMPRKQEARKAALYVFGEKSQLRNFKSDQNSKCDFIPYDYYETRH
|. |.|||                                           |.. ....|..||||||||.||||||.|.||...||..|||....|.|.
ggkgatlk...........................................ennakeskklrarkaaLYvlgeksqlknvksevdskaefipvelveirq

IKASFKKLMKACLPSNPMTDPEMG-FHKMVGESEWLLQIQNIMQLAGAAVDLIDLQGSSVWLSFEDGWDFTTQVSALAQLLMDPYYRTLAGFKVLVDKEW
.|||||||..|||||......|.  |.|.|..|||| ||....||.||.|||.|||||||..|.|||||.|.|||.|||||.|||||||.||||||.|||
vkasfkkllraClpstaveeaesqsFlksvedseWlqqissllqlsgavvdlldlqgssvlvslEdGwdvtaqvsslaqllldpyYRtleGFkvLveKEW

LAFGHRFTHRTNQTITHQTSGFAPVFLQFLDCVHQVHSQFPLSFEFNQYFLKTIAYHYVSNRFQTFMWDSDYERYQAATqVYEERRPSRIDESGdsdset
||||||||.|.|||...|.|||||||||||||||||..||||.||||...||..|||.|||||.||..||.|||..... .|||....|....|      
LafGHrFtkrsnqtlsaqssgfaPvFlqFLDcvhqvsrqfPlafefndfylkflayhsvsnrfrtfllDseyerlesgl.lyeekaekrakkag......

pspplKSLWDYMDKYHPRSPIFYNFQFAP-HTTVLRPYTNTSSLIIWDYFLKENL
     ||.|||.|..|.||||||||...| ...||||..|.||| .|||.|.|.|
.....ksvwdyidrqhkrspifynflyspdesevlrPssnvsslkvWdyyleeel

Myotubularin-like phosphatase domain 1061-1535 2.7e-96 315.4 Pfam-A 18-352 (353) alignment
Myotubularin-like phosphatase domain 1061-1535 2.7e-96 315.4 In-house 18-352 (353) alignment
subfamily_MTMR10_pd Subfamily MTMR10 1090-1155 2e-08 25.4 In-house 21-86 (380) alignment
Range on Protein: 1090-1155
Range on HMM: 21-86/380.0
RVGDMFKISEVNSKFEVSRSYPALIVVPSVLSDDSIRRLAKCHRHGRLPAITWRHQRTKGLLIRSS
 | | .. . .| .|..  ..|  .|||  |||. ..|| . .. .| |  .| | ... ||. | 
tvsdaivvllknelfaaaqtlPqyfvvpnslsdsdverlsrhykesRfplwvwshakgaallrlsa

subfamily_MTMR3_pd Subfamily MTMR3 1091-1155 1.3e-16 53.5 In-house 40-104 (442) alignment
Range on Protein: 1091-1155
Range on HMM: 40-104/442.0
VGDMFKISEVNSKFEVSRSYPALIVVPSVLSDDSIRRLAKCHRHGRLPAITWRHQRTKGLLIRSS
. ....||.|||.|.. .|||  ..||....||.... |.    .||||. |||.... .|.|.|
lkeawrisdvnsdfklCssyPkklivPksitdddlkkvasfrslkrlPavvwrhkkngavlarcs

subfamily_MTMR9_pd Subfamily MTMR9 1091-1155 5e-15 47.5 In-house 30-94 (393) alignment
Range on Protein: 1091-1155
Range on HMM: 30-94/393.0
VGDMFKISEVNSKFEVSRSYPALIVVPSVLSDDSIRRLAKCHRHGRLPAITWRHQRTKGLLIRSS
. | ..||.|| .|.|  |||. ..||  ..|....  |.  ..||.| ....|..||  |.|||
asdewRissvNknfkvcasypesvivPkaiddeelkasaafreggrfPvLsylhketkavllrss

subfamily_Dicty-MTMR1-like_pd Subfamily Dicty-MTMR1-like 1094-1155 6.6e-15 47.2 In-house 35-96 (404) alignment
Range on Protein: 1094-1155
Range on HMM: 35-96/404.0
MFKISEVNSKFEVSRSYPALIVVPSVLSDDSIRRLAKCHRHGRLPAITWRHQRTKGLLIRSS
 ..||..||..|.. .|| |.|||. .||. . . |.   .||.|...|||. ..  ..|||
eWriskinsdyelcetYPkllvvPesisDeelkkvasfRskgRiPvlswrhrsknstitRss

subfamily_MTMR1_pd Subfamily MTMR1 1094-1158 5.4e-14 44.3 In-house 26-90 (389) alignment
Range on Protein: 1094-1158
Range on HMM: 26-90/389.0
MFKISEVNSKFEVSRSYPALIVVPSVLSDDSIRRLAKCHRHGRLPAITWRHQRTKGLLIRSSGFH
...|...|.|.|.. .|||..|||.| ||. ... |. . .|||| ..| .....  ..|.|   
lWritklnkkyelcdtYpavlvvpkvvsdedlkkvaafrskgRlPvlswlnkenqavilrasqpl

subfamily_MTMR6_pd Subfamily MTMR6 1094-1155 4.5e-06 18.2 In-house 37-98 (397) alignment
Range on Protein: 1094-1155
Range on HMM: 37-98/397.0
MFKISEVNSKFEVSRSYPALIVVPSVLSDDSIRRLAKCHRHGRLPAITWRHQRTKGLLIRSS
 ......| ..|.  .||  ..||.  . . .   .|   .|||| ... |....  . |.|
kwtltdlnkdyelcdtyprelyvPksatkevlvgsskfrskgrlPvlsylhkeneaaicrcs

subfamily_MTMR1_pd Subfamily MTMR1 1342-1537 1.4e-57 187.7 In-house 142-334 (389) alignment
Range on Protein: 1342-1537
Range on HMM: 142-334/389.0
SDQNSKCDFIPYDYYETRHIKASFKKLMKACLPSnpmTDpEMGFHKMVGESEWLLQIQNIMQLAGAAVDLIDLQGSSVWLSFEDGWDFTTQVSALAQLLM
...  ....|  |  . . ...|.||| ...||.   .| .  . . . ...|| .|. |.. | . |. .. . .|| . ..|||| |.|. .||.||.
eeaYknaelifldihnihvvReslkklkelvlpn...vd.dkkwlsalestkWlehiklilagavkivekvetektsvlvhcsdGWDRtaqltsLamlll

DPYYRTLAGFKVLVDKEWLAFGHRFTHRTNQ-TITHQTSGFAPVFLQFLDCVHQVHSQFPLSFEFNQYFLKTIAYHYVSNRFQTFMWDSDYERYQAA
|.||||. ||.||..||||.|||.|..|. .    ....  .||||||.|||.|.. |||  ||||. || |.. |. | .| ||...|. || .. 
DsyyRtieGfevliekeWlsfGHkfkeRlghgdknssdaersPvFlqfiDcvwqltrqfptAFefneefLitlldhlysclfGtflfnsekervkek

subfamily_Dicty-MTMR1-like_pd Subfamily Dicty-MTMR1-like 1346-1537 4.3e-56 182.8 In-house 155-343 (404) alignment
Range on Protein: 1346-1537
Range on HMM: 155-343/404.0
SKCDFIPYDYYETRHIKASFKKLMKAClpsNPMTDPEMGFHKMVGESEWLLQIQNIMQLAGAAVDLIDLQGSSVWLSFEDGWDFTTQVSALAQLLMDPYY
..|.       .  ... |.||| ||.   | ... | .. . . .|.|| .|..... .  .|.||. ..||| .   |||| |.|.|.|.|||.||||
enceieflnienihelreslkklkkav...nsiiekeknwlselessrWldhiklllegskriveliekekssvlvhcsdgwDrtsqlsslsqllldpyy

RTLAGFKVLVDKEWLAFGHRFTHRTNQTITHQTSGFAPVFLQFLDCVHQVHSQFPLSFEFNQYFLKTIAYHYVSNRFQTFMWDSDYERYQAA
||. ||.||..|||| ||| |..|..|| ..... ..|.||||.|||.|.  ||| |||||. ||..| ..  |.|| ||..||. || |. 
rtiegFivliekewlsfGhkfaqRigqttekssdersPiflqFidcvyqltkqfptsFeFnekflikildalyscrfgtFLydsekeRqqnn

subfamily_Ank-MTMR1_pd Subfamily Ank-MTMR1 1348-1537 4.5e-39 126.3 In-house 162-353 (405) alignment
Range on Protein: 1348-1537
Range on HMM: 162-353/405.0
CDFIPYDYYETRHIKASFKKLMKACLPSNPMT----DPEMGFHKMVGESEWLLQIQNIMQLAGAAVDLIdLQGSSVWLSFEDGWDFTTQVSALAQLLMDP
| ..  .  .   |. |..||. |   |          .| |  .. |. |. .|. |.. |  . .|| |.| |. .   |||| | |...|.|.|.||
cklvfmnipnihvirksleklvlamkssardkdhtestdmrfwgyieetgwishiksileaatfsaeli.lkgnsilvhcsdgwdrtpqitsltqilldp

YYRTLAGFKVLVDKEWLAFGHRFTHRTNQtITHQTSGFAPVFLQFLDCVHQVHSQFPLSFEFNQYFLKTIAYHYVSNRFQTFMWDSDYERYQAA
||||. ||.||..||||.|||.|. |  . .  .    .|.| |||||. |. ||||| |||   .|  |.    | .. ||. . . .| |  
yyrtivgfqvliekewlsfghkfslrlgh.lpgneeerspifqqfldccfqllsqfpllfeftpslllfisdnihsckygtflnncekdrvqdq

subfamily_MTMR6_pd Subfamily MTMR6 1353-1536 6.1e-48 156.0 In-house 163-342 (397) alignment
Range on Protein: 1353-1536
Range on HMM: 163-342/397.0
YDYYETRHIKASFKKLMKACLPSNPMTDpemGFHKMVGESEWLLQIQNIMQLAGAAVDLIDLQGSSVWLSFEDGWDFTTQVSALAQLLMDPYYRTLAGFK
 .  .   ...| .||....  ... .     | . . .|.||  |..... .      .  .| || .   |||| |.|| .||.||.||||||. ||.
vgienihvmreslqkllevvelksksvs...eflsglessgwlkhikavldasifiakavaeegasvlvhcsdGwdrtaqvcslasllldpyyrtikGfl

VLVDKEWLAFGHRFTHRTNQtITHQTSGFAPVFLQFLDCVHQVHSQFPLSFEFNQYFLKTIAYHYVSNRFQTFMWDSDYERYQA
||..||||.|||.|..|. . . ...  ..|.|.|||.|| |. .||| .||||. || ..  |  | .| ||. ... .| ..
vliekewlsfGhkfsercGl.ldedskevsPiftqflecvwqlleqfpkafefnerfllelhdhvyscqfGtflgncekdrrdl

subfamily_pats1_pd Subfamily pats1 1355-1471 1.9e-17 54.9 In-house 343-458 (691) alignment
Range on Protein: 1355-1471
Range on HMM: 343-458/691.0
YYETRHIKASFKKLMKACLpsnpMTDPEMGFHKMVGESEWLLQIQNIMQLAGAAVDLIDlQGSSVWLS-FEDGWDFTTQV---SALAQLLMDPYYRTLAG
     .... | .|... |      |  .   | . || |.  .. ... |     |.| .|||| |    |. ... ..   |.|||.|.||.|||| |
lPtrekveerffdllqsil....sldgsddewkeieeskwvdsvkllleaavkvsnlld.eGssvllknsidsPlieldlasisslaqvlsdPfyrtldG

FKVLVDKEWLAFGHRFTHRTN
||||..|||| .|. |.... 
fkvliekewlsyGfPfskiny

subfamily_MTMR3_pd Subfamily MTMR3 1357-1538 1.9e-49 161.6 In-house 214-392 (442) alignment
Range on Protein: 1357-1538
Range on HMM: 214-392/442.0
ETRHIKASFKKLMKACLpsnPMTDpEMGFHKMVGESEWLLQIQNIMQLAGAAVDLIDLQGSSVWLSFEDGWDFTTQVSALAQLLMDPYYRTLAGFKVLVD
    .. ||..| . .     ..| |. ..  . . .|| .. .... |   |. .| .| .| .   |||| |||. |||.||.||||||| ||||||.
nihavrksfnslralls...qspd.esnwlsalektkWlqnlsvllkaavkvveavdkegrpvlvhCsdGWdrttqivalakllldpyyrtleGfkvlve

KEWLAFGHRFTHRTNQTIT-HQTSGFAPVFLQFLDCVHQVHSQFPLSFEFNQYFLKTIAYHYVSNRFQTFMWDSDYERYQAAT
.|||.|||.|. |. .    ...   .|||||.||.|||.. ||| |||||. ||  .. |  |  | ||. .|  || . ..
reWldfGhkfadrcghgenvddanercPvflqwldavhqlqrqfPtsfefneaflvklvqhtysclfGtflansekereeekv

subfamily_MTMR9_pd Subfamily MTMR9 1357-1536 4.1e-46 149.8 In-house 161-339 (393) alignment
Range on Protein: 1357-1536
Range on HMM: 161-339/393.0
ETRHIKASFKKLMKACLPSNPMTDpemGFHKMVGESEWLLQIQNIMQLAGAAVDLIDLQGSSVWLSFEDGWDFTTQVSALAQLLMDPYYRTLAGFKVLVD
....|. |. ||..||   .  ||    | . . .| || |.......|  .....| .|..| .  |.| | | ||..||||..||..||. ||. |..
svasiqdslaklleacsdaglstd...kflsrleksgwlsqvadlleaalvvaqcldeegapvvvhgeeGlDatlqvtsLaqlildpdaRtvrgfealie

KEWLAFGHRFTHRTNQTITHQ--TSGFAPVFLQFLDCVHQVHSQFPLSFEFNQYFLKTIAYHYVSNRFQTFMWDSDYERYQA
.||.  || |..|....  ..  .   .|||| |||||.|. ||||.|||||. .| ..  |  | .| ||. |.. || ..
reWiqaGHPFasRaskvaaketkkklsgpvfllFLDcvyqilsqfpasFEFneelLillfehsyssqfgtflcdneaerkel

subfamily_MTMR10_pd Subfamily MTMR10 1357-1546 1.8e-42 137.5 In-house 125-311 (380) alignment
Range on Protein: 1357-1546
Range on HMM: 125-311/380.0
ETRHIKASFKKLMKACLPSNPM--TDPEMGFHKMVGESEWLLQIQNIMQLAGAAVDLIDLQGSSVWLSFEDGWDFTTQVSALAQLLMDPYYRTLAGFKVL
  . ......||.. |.....    . . ..     ...||  .. ....|  ||...  .. || |. ..| |    |. ||||..||.|||. ||. |
siqdvqkaylklreLcvidtseefvtlddkwlssLektrWLayvrlclstasdavktvvekkrsvilqesegrDlscvvaSLaqlmldphyrtisGfqsl

VDKEWLAFGHRFTHRTNQTITHQTSGFaPVFLQFLDCVHQVHSQFPLSFEFNQYFLKTIAYHYVSNRFQTFMWDSDYERYQAATQVYeerrP
..||| | || |..| ...   ..|   |||| |||||.| . ||| .|||.. || ..  . .|  |.||. .|. .| .| ..      |
iqkewvaaghpfldrlghikpsekses.pvfllFldcvdqlleqfpseFeFtetfLialwdsshsgifltflfnseeqrlkavvsss....p

subfamily_pats1_pd Subfamily pats1 1479-1533 5.1e-12 37.0 In-house 550-604 (691) alignment
Range on Protein: 1479-1533
Range on HMM: 550-604/691.0
SGFAPVFLQFLDCVHQVHSQFPLSFEFNQYFLKTIAYHYVSNRFQTFMWDSDYER
 .|.|.|.|||| | |.. .||. ||||...| ..  .  | || .|...   ..
rsfsPifvqfldlvwqlqkefPfhfefneslllllvkesfssrfGnflyseakrd

C1_1 Phorbol esters/diacylglycerol binding domain (C1 domain) 1739-1792 6.6e-14 41.4 Pfam-A 1-51 (53) alignment
Range on Protein: 1739-1792
Range on HMM: 1-51/53.0
HHFEPCSYMTPTSCDFCNQMLfgvVKQGCTGMKCSDCGYNVHEKCVPQVPKQCS
||... ..  ||.|. |...|    ..|..|.|||.|...||.||...|||.| 
HhwvhrnfkqptfCkhCgkfl...wgkgkqglkCswCqllvHkkCfekvpkecg

PH PH domain 1859-1883 7.8e-06 16.4 Pfam-A 3-27 (104) alignment
Range on Protein: 1859-1883
Range on HMM: 3-27/104.0
HEGHLYKRGARLKGWKQRWFVLDSQ
.|| |.|.. .|| ||.|.||| |.
keGyllkksellktwkkryfvLtsn