Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
---|---|---|---|---|---|---|---|---|---|
subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 645-932 | 9.1e-40 | 131.5 | In-house | 7-277 (315) | alignment | ||
Range on Protein: 645-932
Range on HMM: 7-277/315.0
PSHTLTSNALAKFYSYREAIAEEFENLPGHQLIAsSDIKKRIAVpvTSKPRSPVIQSPERTRVPIPPTSptspsipSKPSDFFLDASFIRGYDSSHcSYI
| | . | | .. . ...|..|| || |. |.| | | | . ...|| .| . .| ...|.|| ||. . ||
pldqlityvaqkkastkngfkqdyesipggqlhp.ldvakkien..kqknryiniiaydksrvqlplle.......ndphsdyvnanfidGynkkr.ryi
GATVSGGDSSTAFWRTVWEQQSRTIVCLCSPYELGK-VCPQYWPTKeggpgTQLYGNILVTLKGGASGEHYFTSTLliRNVEKSLCRPVTHYWFSNWLDS
.| | ||| |.|.. .|| | . | | . .||| | .||.| ||.| ..| || | .. | | . .. | |.
aaqgpnvasvkdfwrlvfeedigkivmltnlvegekrkaekywpdk.....kviyGkitvtrkseevnteytvrtl..svvfgdnirevvqlhytswpdm
EIPSSPQALMSMLLQVHNTHQESYGPVVVHCSDGVGRTGLVIATDINMQRLEESHTVDIPHTVSSIRQDRGQAILNIDQYAFIYRTLYE
..| . .|| . .|. |..| |..|||||.|||||| |. | ....| . .|. . . .|| | ... ..|| ||| .| |
gvpkytiplmnlirtvkqhhtnsvgaivvhcsaGvGrtGtfitldavldqaeaenaidvynfitgvrqnrikmvqvaeqyqfiydalle
|
|||||||||
0051299 | (Phosphotyrosine protein) phosphatases II | 649-933 | 1.1e-60 | 200.9 | In-house | 10-285 (288) | alignment | ||
Range on Protein: 649-933
Range on HMM: 10-285/288.0
LTSNALAKFYSYREAIAEEFENLPGHQLIasSDIKKRIAVPVTSKPRSPVIQSPERTRVPIPptsptspSIPSKPSDFFLDASFIRGYDSSHCsYIGATV
|.. |.. . ..|||| |. . ... . . .| |.. | ...|| . .... ... . .||.|.||.... .| .
llklvlkllangltglleefeellsllpd..ltlsaallpenleknRysdilpydhsRVkLs.......vldgvegsdYinAsyidgynlkrk.fIatqg
SGGDSSTAFWRTVWEQQSRTIVCLCSPYELG-KVCPQYWPTkeggPGTQLYGNILVTLKGGASGEHYFTSTLLIRNV----EKSLCRPVTHYWFSNWLDS
.. ||| ||||..|.||.|....||| . |.||||. |.. ||.| |||. . ..| . || ..|. .. .| |||... || |
PlpntvedFWrmvweqnvrvIvmltklvelgrekcaqYwpl....ggsltygditvtllseevlddytvrtlevtnldlldgdgesrtvthfhytnwpdh
EIPSSPQALMSMLLQVHNTHQESYGPVVVHCSDGVGRTGLVIATDINMQRLEESHTVDIPHTVSSIRQDRGQAILNIDQYAFIYRTLYEF
.|.||..|...| .|.. .. . ||||||||.|||||| .|| |. ...||. ..||....| .|. | ... . .|| |.|..|.|.
gvpdspellldflrlvrkalasgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlreqRpgmvqtpeqyrfvyealley
|
|||||||||
0043336 | (Phosphotyrosine protein) phosphatases II | 649-933 | 9.1e-56 | 184.7 | In-house | 7-276 (278) | alignment | ||
Range on Protein: 649-933
Range on HMM: 7-276/278.0
LTSNALAKFYSYREAIAEEFENLPGHQLiasSDIKKRIAVPVTSKPRSPVIQSPERTRVPIPPtsptspsIPSKPSDFFLDASFIRGYDSSHCsYIGATV
| | ...... .. .|||.|. .| ... . . .| |.. | ...|| . . ... ... . ||.. ||. .. .| .
llkallelllnlktllllefeellsfkl...dtysiallpenkdknrykdilpydhsrvklsl.......lggdldsdYinAsyvdgynvprk.fiatqg
SGGDSSTAFWRTVWEQQSRTIVCLCSPYELGKV-CPQYWPtkeggPGTQLYGNILVTLKGGASGEHYFTSTLLIRNVEKSLCRPVTHYWFSNWLDSEIPS
.. ||| |||....|||.|... |||.| | |||| |.. ||.. |||.. . ..| . || . | .. .| ||||.. .| | ..|.
PlpetvedFwrmvwelgvttivmLtelvelgrvkcaqYwp.....ggsltygdftvtllkeehlddytvrtlevtnlgdgesrtvthyhylgwpdhgvpe
SPQALMSMLLQVHNTHQESYGPVVVHCSDGVGRTGLVIATDINMQRLEESHTVDIPHTVSSIRQDRGQAILNIDQYAFIYRTLYEF
|.. |...| .|.. . | |||.||||.||||||..|| .. ...|| ..||....|. .|. |..|. . .|| |.|. |.|.
slsllldflkavrealedsngpvlVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqRpgavqtpsqyrflyealley
|
|||||||||
0045450 | (Phosphotyrosine protein) phosphatases II | 654-933 | 5.7e-55 | 182.6 | In-house | 19-303 (307) | alignment | ||
Range on Protein: 654-933
Range on HMM: 19-303/307.0
LAKFYSYREAIAEEFENLPGHQLIASSDIKKRIAVPVTSKPRSPVIQSPERTRVPIPPTSptspsiPSKPSDFFLDASFI--------RGYDSsHCSYIG
| . . .. ...||| |. . . . ... . .| |.. | ..||| . ... .| ... . .||.. |||. .|
llllldfltgllkefekllsvtvfllgeysiallpenkdknrykdilpydhtRVklssld......gsledsdYiNAsyvrvpllllldgydl.krkfIa
ATVSGGDSSTAFWRTVWEQQSRTIVCLCSPYELGKV-CPQYWPTKeggPGTQLYGNILVTLKGGASGEHYFTSTLLIRNV-EKSLCRPVTHYWFSNWLDS
. . .. ||| .|||....||.|... |||.. |.||||.. ... |||. |||.. ..| || . . ... | |||... .| |
tqgPlpetvedFwrmlweqgvtvivmltelvelgrekcaqywPde...geeltygnftvtllseehldgytvrtlevtdldgtgesrtvthfhytgwpdh
EIPSSPQALMSMLLQVHNTHQE--SYGPVVVHCSDGVGRTGLVIATDINMQRLEESHT---VDIPHTVSSIRQDRGQAILNIDQYAFIYRTLYEF
.|.|.. | ... .|.. ..| . |||.||||.|||||| .|| .. ...||. .| ||....|. .|. |..|. | .|| |.|. |.|.
gvppsfeelldfieevrkaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrflyeallel
|
|||||||||
0040438 | (Phosphotyrosine protein) phosphatases II | 657-936 | 1.8e-56 | 187.1 | In-house | 13-278 (317) | alignment | ||
Range on Protein: 657-936
Range on HMM: 13-278/317.0
FYSYREAIAEEFENLPGHQLIassDIKKRIAVPVTSKPRSPVIQSPERTRVPIPPtsptspsIPSKPSDFFLDASFIRGYDSSHCsYIGATVSGGDSSTA
..| |. ||||.|. .| ... . . .| |.| | ...|| . | ... ... . ||.. |.. .. .| . . ..
lksdftalleefedllslkld...tysvaelpenkdknrypdilpydhsRVkLsp.......lggdldsdYInAsyvdgpnlkrk.fIatqgPlpntved
FWRTVWEQQSRTIVCLCSPYELG-KVCPQYWPTkeggPGTQLYGNILVTLKGGASGEHYFTSTLLIRNVEKSLCRPVTHYWFSNWLDSEIPSSPQALMSM
||| ||||....||.|... ||| . | ||||. .|. ||.. |||.. ... || . . ..| .| |||... .| | .|.||. | ..
FwrmvweqgvtvivmLteleelgrekcaqYwpl....getltygdftvtllseeelagitlrtlevedlgdsesrtvthfhytgWpdhgvppspdllldf
LLQVHNTHQESYGPVVVHCSDGVGRTGLVIATDINMQRLEESHTVDIPHTVSSIRQDRGQAILNIDQYAFIYRTLYEFSKF
| .|.. ... |||.||||.|||||| .|| .. ...||. ..||....| .|. |..|. . .|| |.|. |.|. |.
leavrealedpggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrflydalleylkr
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 658-862 | 3.5e-103 | 339.6 | In-house | 1-193 (319) | alignment | ||
Range on Protein: 658-862
Range on HMM: 1-193/319.0
YSYREAIAEEFENLPghQLIASSDikkriAVPVTSKPRSPVIQSpertrVPIPPTSPTSPSIPSKPSDFFLDASFIRGYDSSHCSYIGATVSGGDSSTAF
...||..||||..|| ||||..| .||||||..|.||.. ||.|.|......|.....|..||||..||||....|||.|.||..|||..|
verredvaeefrdlP..qliarad.....evPvtskdksrvinv.....vPlPetrvvlqrigdddkdeyldasyvrGyddapnsyiaaqvsledsssdf
WRTVWEQQSRTIVCLCSPYELG-KVCPQYWPTKEGGPGTQLYGNILVTLKGGASGEHYFTSTLLIRNVEKSLCRPVTHYWFsNWLDSEIPSSPQALMSML
||||||||||.||.|....||| |||..|.||||....|.|||.|||||||......|..||||...|.|...|..||||. .||..|.|....||..||
wrtvweqqsrvivqltdlselGikvcaeylPtketldntslyGdilvtlkgrevkdryaistlllkrvdkeesrelthywy.kwleaevPaeeaaliaml
LQVHNT
|.|...
levrss
|
|||||||||
subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 659-938 | 5.3e-48 | 158.7 | In-house | 20-287 (319) | alignment | ||
Range on Protein: 659-938
Range on HMM: 20-287/319.0
SYREAIAEEFENLPGHQLIassDIKKRIAVPVTSKPRSPVIQSPERTRVPIPptsptspSIPSKPSDFFLDASFIRGYDSSHcSYIGATVSGGDSSTAFW
. ...||..| . . .... .| | . | . .|||| .. ... ... ...|||| ||. . .| . . ||
tgetllekefkllkeavnd...tfdsaskeenkkknryqnilaydrtrvvls.......eldgvegsdyinasfidgyqere.kfiatqaPlentiedfW
RTVWEQQSRTIVCLCSPYELGKV-CPQYWPTKEggpgTQLYGNILVTLKGGASGEHYFTSTLLIRNVEKSL-CRPVTHYWFSNWLDSEIPSSPQALMSML
| |||..| ..| |. | .|| . .|||... . ||...|||. |.| . | ... . .| |.|. . .| | ..| . ..|. .|
rmvWeeessivvmltklveklkvklkkywpeen....feeyGrlivtleeeeeledyiirklklnkkssevetRevkhfqyteWpdhdvPekatslldll
LQVHNTHQE-SYGPVVVHCSDGVGRTGLVIATDINMQRLEESHTVDIPHTVSSIRQDRGQAILNIDQYAFIYRTLYEFSKFLS
........ . ||.|||||.|||||| |. |. ..|..| ..|. .||| .| | . . .|| ||| .| |. .. .
krirksrektqsgPivvhCsaGvGRtGtfivldamlervkeegvlDvfstvsrlRtqRnimvqrpeqYkfiyealleaveagd
|
|||||||||
0050432 | (Phosphotyrosine protein) phosphatases II | 661-935 | 6.4e-61 | 201.7 | In-house | 41-300 (308) | alignment | ||
Range on Protein: 661-935
Range on HMM: 41-300/308.0
REAIAEEFENLPGHQLiaSSDIKKRIAVPVTSKPRSPVIQSPERTRVPIpptsptspsipsKPSDFFLDASFIRGYD-SSHCSYIGATVSGGDSSTAFWR
. . |||| |. . . ... . .| |.. | ...|| . .... . .||...||. . . .| . .. |||
lglleeefeellsvkp..lleysvallpenkdkNrykdilpydhsRVkl............degsdYInAsyvdgyssklprkfIatqgPlpntvedFwr
TVWEQQSRTIVCLCSPYELG-KVCPQYWPTKEGGpGTQLYGNILVTLKGGASGEHYFTSTLLIRNVEKSLCRPVTHYWFSNWLDSEIPSSPQALMSMLLQ
||||..|.||.|....| | . |.||||...|| |.. ||.. |||. . ..| . || ..|.... | |||... || | .|.||..|...| .
mvweqnvrvIvmLtklvengrekcaqYwplelgg.gsleygkftvtllseevlddytvrtleltnlgdgesrtvthfhytnWpdhgvPpspeilldflel
VHNTHQEsyGPVVVHCSDGVGRTGLVIATDINMQRLEESHTVDIPHTVSSIRQDRGQAILNIDQYAFIYRTLYEFSK
|...... ||.|||||.|||||| .|| |. ...||. ..||....| .|. | ... . .|| |.||.|.|. |
vrkslpg..gpivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkklReqRpgmvqtpeqylflyralleylk
|
|||||||||
0036941 | (Phosphotyrosine protein) phosphatases II | 661-935 | 1.6e-58 | 193.7 | In-house | 12-278 (297) | alignment | ||
Range on Protein: 661-935
Range on HMM: 12-278/297.0
REAIAEEFENLPGHQLIASSDIKKRIavPVTSKPRSPVIQSPERTRVPIpptsptspsipSKPSDFFLDASFIRGYDSSHCsYIGATVSGGDSSTAFWRT
. . .||| |. ..|. | .. .. .| |.. | ..||| . ..... . .||.. ||| .. .| . .. |||
lalllkefeellpllllgslsvallp..enleknRykdilpydhtRVkl...........ddegsdYinAsyvdgydlkrk.fIatqgPlpntvedFWrm
VWEQQSRTIVCLCSPYELGKV-CPQYWPTKEGGPGTqlYGNILVTLKGGAS--GEHYFTSTLLIRNVEKSLCRPVTHYWFSNWLDSEIPSSPQALMSMLL
||||....||.|....|||.. |.||||..||.. | ||.. |||.. . ..| . || . ..... | |||... .| | .|.||. |....
vweqnvtvIvmltelvelgrekcaqywpleegeslt..ygdftvtllsvevvllddytlrtlevtdtgngesrtvthfhytgwpdhgvpespaslldfie
QVHNTHQE--SYGPVVVHCSDGVGRTGLVIATDINMQRLE---ESHTVDIPHTVSSIRQDRGQAILNIDQYAFIYRTLYEFSK
.|.. ... | |||.||||.||||.| .|| |. .|.|| . ..|||. .| ..|. | .|. . .|| |.|..|.|. |
lvrkvlkllpsggpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyeallellk
|
|||||||||
0039614 | (Phosphotyrosine protein) phosphatases II | 661-935 | 8.6e-57 | 188.2 | In-house | 31-290 (297) | alignment | ||
Range on Protein: 661-935
Range on HMM: 31-290/297.0
REAIAEEFENLPGHQLiassDIKKRIAVPVTSKPRSPVIQSPERTRVPIPPTSptspsiPSKPSDFFLDASFIRGYDSSHCSYIGATVSGGDSSTAFWRT
. . .|||.|. . |.. . .| |.. | ...|| . | . ... . ||.. ||| .| . .. |||
ktllllefeellslkp....dysiallpenkdknrykdilpydhsrvklkped......gvdldsdYinAsyvdgydlltrkfIatqgPlpetvedFwrm
VWEQQSRTIVCLCSPYELGKVCPQYWPTKEGgpgtqLYGNILVTLKGGASGEHYFTSTLLIRNveKSLCRPVTHYWFSNWLDSEIPSSPQALMSMLLQVH
||||....||.|... |||. |.||||...| ||.. |||.. ..|.. || ..| .. | |||... .| | .|.|.. |...| .|.
vweqgvtvivmLtklvelgrkcaqywpeegg.....tygdftvtllkvehldgytvrtlevtn..ngesrtvthfqytgwpdhgvppslellleflelvr
NTHQE--SYGPVVVHCSDGVGRTGLVIATDINMQRLEESHTVDIPHTVSSIRQDRGQAILNIDQYAFIYRTLYEFSK
. ..| . |||.||||.|||||| .|| .. ...||. ..||....|. .|. |..|. . .|| |.|. |.|. |
ealaelpkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavqtpsqyrflydallellk
|
|||||||||
subfamily_PTPRA_pd | Subfamily PTPRA | 661-934 | 3.3e-44 | 146.1 | In-house | 31-295 (330) | alignment | ||
Range on Protein: 661-934
Range on HMM: 31-295/330.0
REAIAEEFENLPGHQLIASSDIKKRIAvpVTSKPRSPVIQSPERTRVPIPPTSPTspsipsKPSDfFLDASFIRGYDSSHcSYIGATVSGGDSSTAFWRT
. . |||..|| .. |. .. .. | | . | . .|| ... . . . || ...|||| || . ..| | .. |||
nklfreefnalPagpiqatlelaskee..nkeknrvvnilPydfsrvilsvkeGv......eesd.yinasfidGykekd.kfiaaqGPkeetvedfwrm
VWEQQSRTIVCLCSPYELGK-VCPQYWPTKeggpGTQLYGNILVTLKGGASGEHYFTSTLLIRNVEK----SLCRPVTHYWFSNWLDSEIPSSPQALMSM
.|||.| ||| | | . | ||||.. |. |||| |... ..| .|.... . | |. . | | | .|. |. ....
iweqksativmltelkerkeekcaqywPde....GlvtyGnirvevedetvlvdytvrkflvqqlpdatrekksrlvrqfhftswPdvGvPfepiGmlkl
LLQVHNTHQESYGPVVVHCSDGVGRTGLVIATDINMQRLEESHTVDIPHTVSSIRQDRGQAILNIDQYAFIYRTLYEFS
| .|....| | ||.||||| |||||| |. | ..|.. . ||. ..|...|. | | . || |||..| |.
lkkvkklnqqsagpivvhcsaGvGrtGtfivldavlervkaerkvdvfefvkrlrlqrpqmvqtdeqyefiykvlleyy
|
|||||||||
0047943 | (Phosphotyrosine protein) phosphatases II | 662-933 | 7.7e-59 | 194.7 | In-house | 12-271 (273) | alignment | ||
Range on Protein: 662-933
Range on HMM: 12-271/273.0
EAIAEEFENLPGHQLiaSSDIKKRIAVPVTSKPRSPVIQSPERTRVPIpptsptspsipSKPSDFFLDASFIRGYDSSHCsYIGATVSGGDSSTAFWRTV
..|||| |. . . ... . . .| |.. | ...|| . . ... . ||...||.... .| . .. ||| |
tllleefelllslkp..lltysvallpenkdknrykdilpydhsrvkl...........gdggsdyinAsyvdgynlkrk.fiatqgPlpntvedfwrmv
WEQQSRTIVCLCSPYELGKV-CPQYWPTKEGGpGTQLYGNILVTLKGGASGEHYFTSTLLIRNVEKSLCRPVTHYWFSNWLDSEIPSSPQALMSMLLQVH
|||..|.||.|....|||.. |.||||...|. .. ||.. |||.. . ..| . || ..|.. . .| |||... .| | .|.|.. |.... .|.
weqnvrviVmLtelvelgrekcaqYwplegge.lsltygkftvtllseetkddytvrtleltnlgtgesrtvthfhytgwpdhgvppslesllefielvr
NTHQE--SYGPVVVHCSDGVGRTGLVIATDINMQRLEESHTVDIPHTVSSIRQDRGQAILNIDQYAFIYRTLYEF
..... | ||||||||.|||||| .|| |. ...||. ..||.. .| .|. | .. . .|| |.|..|.|.
kalealpsngpvvVHCsaGvgRtgtfialdllldqlekeggvdvleavkllrsqRpgmvqtpeqyrflyealley
|
|||||||||
subfamily_PTPN6_pd | Subfamily PTPN6 | 662-935 | 6.8e-41 | 135.2 | In-house | 26-298 (306) | alignment | ||
Range on Protein: 662-935
Range on HMM: 26-298/306.0
EAIAEEFENLPGHQLIASSDIKKRIAVPVTSKPRSPVIQSPERTRVPIPptsptspsIPSKPSDFFLDASFIR-GYDSSHCSYIGATVSGGDSSTAFWRT
. . ||||.| .. . |. . ..| | | . ||| . || | . ...|..|. .|..||| . . . . |||
agfeeefeelqqeeakkllsrkegakpenkeknryknilPfDhtrvilk........epsvpgsdyinanyikkevkgsdksyiatqgclettvsdFWrm
VWEQQSRTIVCLCSPYELGK-VCPQYWPTKEGgpGTQlYGNILVTLKGGASGEHYFTSTLLIR-NVEKSLCRPVTHYWFSNWLDSEIPSSPQALMSMLLQ
||...|| || . .| || | .|||..| .. ||.| || | ..| .|.. . .|. .| | .| | .| | .|..|.|....| .
vwqensrvivmttkevErgkekCarYWPdeee..kee.yGkisvtnvseksladYilRelsvskkkkkkeerevfqyhfksWPdhgvpkdpgavLdfled
VHNTHQESY----GPVVVHCSDGVGRTGLVIATDINMQRLEES---HTVDIPHTVSSIRQDRGQAILNIDQYAFIYRTLYEFSK
|.. ..|. ||.|||||.|.|||| .| .|| .. .|.. .|| ..| |.|. | . . .|| |.|... .. .
vnrkqeeleeaeagpivvhCsaGiGRtGtfiviDillkliekkgldadidiqklvksvreqrsglvqteqqykfvykaikkyie
|
|||||||||
subfamily_PTPN23_pd | Subfamily PTPN23 | 662-930 | 8.5e-40 | 131.4 | In-house | 15-276 (288) | alignment | ||
Range on Protein: 662-930
Range on HMM: 15-276/288.0
EAIAEEFENLPGHQLIASSDIKKRIAVPVTSKPRSPVIQSPERTRVPIPptsptspsipsKPSDFFLDASFIRGYDSSHCSYIGATVSGGDSSTAFWRTV
|. ..|..| .| . . || ..| || | ...|| . . | ...|||... . ..| . .. ||. |
taldkkfkeleqkqdkearkrsiaiaklyseknrsrdilPyDhnRvklr...........gskDDYinAsfvkdlspgcPdfiatqaPlqstlnDFWlmv
WEQQSRTIVCLCSPYELGKV-CPQYWPTKEGGpgTQLYGNILVTLKGGASGEHYFTSTLLIRNVEKSLCRPVTHYWFSNWLDSEIPSSPQALMSMLLQVH
.||.|..||.| |. |||| . .|||...| |. .|.. |||| . |.. .| .. ... . |.| . .| . .|.||. |. .| .|.
yeqkssviVmllskeelgkpkvdrYwPedkge..tvkfgdlsvtlksvretethvervlkletldadavksvshlqltsWpelGvPasPetllqfldeve
N----THQESYGPVVVHCSDGVGRTGLVIATDINMQRLEESHT-VDIPHTVSSIRQDRGQAILNIDQYAFIYRTL
. ....| |.||||| ||||||.. .. ||. . .||.. || .|..| . . .|. | |
sayeavqrksktPlvvhCsaGvgRtgvfalvyaavrelekgnglldiiqvvsrlreqRrfmvqekeqlkfsyeav
|
|||||||||
subfamily_Ptp69D_pd | Subfamily Ptp69D | 663-937 | 6.4e-46 | 151.9 | In-house | 23-289 (307) | alignment | ||
Range on Protein: 663-937
Range on HMM: 23-289/307.0
AIAEEFENLPGHQLIASSDIKKRIAvpVTSKPRSPVIQSPERTRVPIPPTSPTspsipsKPSDfFLDASFIRGYDSSHcSYIGATVSGGDSSTAFWRTVW
.|.|.|.|. .. |. . .. . | |.. |.. ..||| .... . . || ...||||.||. .. ..| | ||| ..
glakeyekLeareidkstkvsekke..nalknRyedikafDktRvkLkkingk......edsd.Yinasfikgykekk.kfiaaqdPveatigDfWRmia
EQQSRTIVCLCSPYELGKV-CPQYWPTKeggpGTQLYGNILVTLKGGASGEHYFTSTLLIRNVEKS-----LCRPVTHYWFSNWLDSEIPSSPQALMSML
||.. .|| | | . |..||| .. ||.|||.| . ..| .| . ..... | |. | . .| ||..| ....|. ..
eqevtlivmlsnlteknrkkcakYWpie....devqygdilvklvseekhsdyiiReldvskkkeesgevedsrkvvqyhytgWkDskvPevargllkli
LQVHNTHQESYGPVVVHCSDGVGRTGLVIATDINMQRLEESHTVDIPHTVSSIRQDRGQAILNIDQYAFIYRTLYEFSKFL
||.. .. . .|.||||| ||||.|...| |. .|.|.. ..||| .|| .|..| . ...|| |.|| | ..|..
eqvrelyklnrsPivvhCsaGvgrsgifvaldsllqqlkaedkvdifetvkdLrsqRnllvqsleqYvflyralldyssyg
|
|||||||||
subfamily_PTPRG_pd | Subfamily PTPRG | 663-933 | 5.6e-42 | 138.7 | In-house | 20-286 (563) | alignment | ||
Range on Protein: 663-933
Range on HMM: 20-286/563.0
AIAEEFENLPGHQLIASSDIKKRIAVPVTSKPRSPVIQSPERTRVPIPPTsptsPSIPSKPsDfFLDASFIRGYDSSHcSYIGATVSGGDSSTAFWRTVW
..||||.| . . |... . | | | . .|.|| . |. | . .| | .. |..| || |. .|.. . | ||| .|
gfseefealqsetiskdldaehsqkpenkrKnRylnivaydrsRvklspl....pgkkkkl.D.YinAnyidGyqksk.afiatqgplkdtfddFWrmiW
EQQSRTIVCLCS-PYELGKVCPQYWPTkeggPGTQLYGNILVTLKGGASGEHYFTSTLLIRN--VEKS----LCRPVTHYWFSNWLDSEIPSSPQALMSM
||.. .|| . . . |..|||. ... ||.. |||. | . || |.| ..| . |..| ...| | |... ...
eqnvaiivmitnlvergrrkcdvYWPk....desetygalqvtlieeevlalytvrtlviknlklkkkkqcdteklvrqyhytkWPdhgvPehslpvLif
LLQVHNTHQESYGPVVVHCSDGVGRTGLVIATDINMQRLEESHTVDIPHTVSSIRQDRGQAILNIDQYAFIYRTLYEF
. .... ||.||||| |||||| |. | ...... ..|.. ... || | . ...|| |.. .| |
vkkssaankaeaGPivvHcsaGvgrtGtyivldtllkqiqqenavnvfgflkhiraqRnflvqteEqYiflhdallea
|
|||||||||
0046845 | (Phosphotyrosine protein) phosphatases II | 664-935 | 6.2e-60 | 198.3 | In-house | 2-275 (284) | alignment | ||
Range on Protein: 664-935
Range on HMM: 2-275/284.0
IAEEFENLPGHQLIASSDIKKRIAVPVTSKPRSPVIQSPERTRVPIPPTSPTspsipsKPSDFFLDASFIRGYD----SSHCSYIGATVSGGDSSTAFWR
. |||| |. . . ... ... || |.. | ...|| . ..... ... . .||...||| ... .| . .. |||
leeefeellsltvklllslsvallpenlsknRykdilpydhsRVklksldgd......ledsdYinAsyvdgydldltyikkkfIatqgPlpntvedFwr
TVWEQQSRTIVCLCSPYELGK-VCPQYWPTKeggPGTQLYGNILVTLKGGASGEHYFTSTLLIRNVE-KSLCRPVTHYWFSNWLDSEIPSSPQALMSMLL
||||..|.||.|... | |. |.||||.. ... ||.. |||. ..| . || ..|.. .. | |||... .| | .|.||. |...|
mvweqnvrvIVmltelvengrekcaqYwple...gevltygdftvtllseevkddytvrtleltnlgytgesrtvthfhytswpdhgvppspedlleflr
QVHNTHQ--ESYGPVVVHCSDGVGRTGLVIATDINMQRLEESH---TVDIPHTVSSIRQDRGQAILNIDQYAFIYRTLYEFSK
.|.. .. .. ||.|||||.|||||| .|| |. ...||. . .||....|. .|. | ... . .|| |.|..|.|. |
lvrellenlpgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvqtleqyrfvyealleylk
|
|||||||||
subfamily_Urchin-PTP-4_pd | Subfamily Urchin-PTP-4 | 665-932 | 2.2e-25 | 83.9 | In-house | 23-234 (392) | alignment | ||
Range on Protein: 665-932
Range on HMM: 23-234/392.0
AEEFENLPGHQLIASSDIKKRIAVPvtsKPRSPVIQSPERTRVPIPptsptspSIPSKPSDFFLDASFIRGYDSSHcSYIGATVSGGDSSTAFWRTVWEQ
.||| .||| .. . .| | .. | | | ...|| . | | . .|.||.|...|. . .|| . | ||| |...
feefhdlpgpdiypqtvaqkeinlk...knryknilpydsarvkle.......viddipdsdylnasyipsfdnek.ayiasqgpnaaslddfwrmvfqe
QSRTIVCLCSPYELGkvcpqywptkeggpgtqlygnilvtlkggasgehyftstllirnvEKSLCRPVTHYWFSNWLDSEIPSSPQALMSMLLQVHNTHQ
. ||. . | .| |. . |..| |...| .|. .. .|. .
nvttiamvtklkegd.............................................kgddartvaqfhftewPdkdvpkhtssllkfikevkadfG
ESYGPVVVHCSDGVGRTGLVIATDINMQRLEESHTVDIPHTVSSIRQDRGQAILNIDQYAFIYRTLYE
. |...||| ||||||.||. | . . .... ||. |. ||. | . .|||||| .. |
qythpliihcsagvgrtgvvisidsvvahakktrmvdvfnfvtnirrkrpymvqtkeqyafiygavle
|
|||||||||
subfamily_Cele-PTP-13_pd | Subfamily Cele-PTP-13 | 665-934 | 8.5e-21 | 68.8 | In-house | 14-269 (281) | alignment | ||
Range on Protein: 665-934
Range on HMM: 14-269/281.0
AEEFENLPGHqliASSDIKKRIAVPVTSK-PRSPVIQSPERTRVPIpptsptSPSIPSKPSDFFLDASFIRGYdSSHCSYIGATVSGGDSSTAFWRTVWE
.|| |||| ||. . || | | | . .|| . .| | | .. | .|| . || . .. . ||| .|.
kqefsnlpgd...ppsdlctvfnqpvnnkknrylnipcldisrvql......kvkmpnknstdyihanyirsp.flkrgyiltqgpkketradfwrmiwq
QQSRTIVCLCSPYELGK-VCPQYWPTKEGgpGTQLYGNILVTLKGGASGEHYFTSTLLIrNVEkSLCRPVTHYWFSNWLDSEIPSSPQALMSMLLQVHNT
... .|| || | . | .|.| . . .. |. . . . |. | . | | .||. . .| | ..| | . .. .| ...
enttaivmlcqfletnrekcaeyfprnah..cclqfdklsvsyedstvnkslvttrlnl.sye.getrlithwlwkewpdwqvpessevmlkilrkirar
hqeSyGPVVVHCSDGVGRTGLVIATDINMQRLEESHTV-DIPHTVSSIRQ-DRGQAILNIDQYAFIYRTLYEFS
| | |.||| ||||.| ..| .| .| . |. || . || .| | .. ..|| .|.. | .|
...s.tppvihcsagvgrsgtlmaveialqsihshftlpdikqivshlrvtgraasvqtlqqymliwkvlldfg
|
|||||||||
subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 666-933 | 2.5e-43 | 143.4 | In-house | 26-282 (305) | alignment | ||
Range on Protein: 666-933
Range on HMM: 26-282/305.0
EEFENLPGHqlIASSDIKKRIAVPVTSKPRSPVIQSPERTRVPIPPTSPtspsipskPSDfFLDASFIRGYDSSHCsYIGATVSGGDSSTAFWRTVWEQQ
.....|. . | |..|. | ... ...... ..|... .. . || ...||.. ||..... || | . . |||...| .
aqykslyee..eesidvgkkeankaknrlkeitlldddriiltekesld........dsd.yinasyvdgykrkkk.yivaqgPlkntvadfWrliveek
SRTIVCLCSPYELGK-VCPQYWPTKEGGPgtQLYGNILVTLKGGASGEHYFTSTLLIRN-VEKSLCRPVTHYWFSNWLDSEIPSSPQALMSMLLQVHNTH
.||| |. | || | ||||.... . . .|.. |.|| .. . |.. | | . |.. | |..| . .| | .| .. .|.|.. .|....
vstivmltklveggkdkCrqYWpesktek..kefgefsvelksektasdyieRklkisiededkesrtvlqyqltdWPdhGvpqfatsllslikrvqkdq
QESYG-PVVVHCSDGVGRTGLVIATDINMQRLEESHTVDIPHTVSSIRQDRGQAILNIDQYAFIYRTLYEF
... | |..||||.|||||| || || ..||.. .||. . . .|. | ... . ||| |.. | |
kkdkgvpllVhCsagvgRtGvfiavdialerlkkEevvdvfevlkqlRskrmkmvqtldqYvflhdaldel
|
|||||||||
DSPc_SM00195 | 681-933 | 4.2e-52 | 172.4 | In-house | 17-261 (263) | alignment | |||
Range on Protein: 681-933
Range on HMM: 17-261/263.0
DIKKRIAVPVTSKPRSPVIQSPERTRVPIPPTSPTspsipskPSDFFLDASFIRGYdSSHCSYIGATVSGGDSSTAFWRTVWEQQSRTIVCLCSPYELGK
.... . .|| |. | ..||| .... . ... .. |..|.|. .. .|| . . |||.|||.....||.|... | ||
etteaekkknksknRyknilpydhtrVklkkeekk.......egsdYINAnyikga.nkkkkyIatQgPlpstvedFWrmvweekvkiivmlteeeengk
-VCPQYWPTKEggPGTQLYGNILVTLKGGASGE-HYFTSTLLIRNVEKSLCRPVTHYWFSNWLDSEIPSSPQALMSMLLQVHNTHQESYGPVVVHCSDGV
| .||| .. |.. .|.| |.|. . . .. . || ... .|. | ||.|.. || |...|.|.. ....| .|......| ||.|||||.||
ekcdrywpees..ggketfgkisvklvevekkkdeiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkkskstssgpivVhCsaGv
GRTGLVIATDINMQRLEESHTVDIPHTVSSIRQDRGQAILNIDQYAFIYRTLYEF
|||| ....|| ...||| ..||| ..|...|. | ... . .||.|||... |.
gRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeailey
|
|||||||||
PTPc_SM00194 | 681-933 | 4.2e-52 | 172.4 | In-house | 17-261 (263) | alignment | |||
Range on Protein: 681-933
Range on HMM: 17-261/263.0
DIKKRIAVPVTSKPRSPVIQSPERTRVPIPPTSPTspsipskPSDFFLDASFIRGYdSSHCSYIGATVSGGDSSTAFWRTVWEQQSRTIVCLCSPYELGK
.... . .|| |. | ..||| .... . ... .. |..|.|. .. .|| . . |||.|||.....||.|... | ||
etteaekkknksknRyknilpydhtrVklkkeekk.......egsdYINAnyikga.nkkkkyIatQgPlpstvedFWrmvweekvkiivmlteeeengk
-VCPQYWPTKEggPGTQLYGNILVTLKGGASGE-HYFTSTLLIRNVEKSLCRPVTHYWFSNWLDSEIPSSPQALMSMLLQVHNTHQESYGPVVVHCSDGV
| .||| .. |.. .|.| |.|. . . .. . || ... .|. | ||.|.. || |...|.|.. ....| .|......| ||.|||||.||
ekcdrywpees..ggketfgkisvklvevekkkdeiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkkskstssgpivVhCsaGv
GRTGLVIATDINMQRLEESHTVDIPHTVSSIRQDRGQAILNIDQYAFIYRTLYEF
|||| ....|| ...||| ..||| ..|...|. | ... . .||.|||... |.
gRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeailey
|
|||||||||
0045098 | (Phosphotyrosine protein) phosphatases II | 682-933 | 1.2e-48 | 161.3 | In-house | 25-271 (278) | alignment | ||
Range on Protein: 682-933
Range on HMM: 25-271/278.0
IKKRIAVPVTSKPRSPVIQSPERTRVPipptsptspsipskpsDfFLDASFIRGYdssHCSYIGATVSGGDSSTAFWRTVWEQQSRTIVCLCSPYELG-K
| . . .| | . |. ...|| | ...||.|.|| . .| . . .|||..||.....||.|.. .||| .
itpalylgnldknRykdilpydhsrVk................d.YINAsyidgy...pkkfIatqgPlpstvadfwrmlwelgitvivmltelvelgre
VCPQYWPTkeggPGTQLYGNILVTLKGGASGEHYFTSTLLIRNV----EKSLCRPVTHYWFSNWLDSEIPSSP--QALMSMLLQVHNTHQE---------
|.|||| |.. ||.. |||. ..| . |||..|. | .| |||... .| | ..||.| . . ..| .... ...
kcaqywpe....ggsltygdftvtllseevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllssl
----SYGPVVVHCSDGVGRTGLVIATDINMQRLeEsHTVDIPHTVSSIRQDRGQ-AILNIDQYAFIYRTLYEF
| |||.|||| |||||| ..| .. ...| | ..||....|. .|. |.. |. | .|| |.|. |.|.
llldsggpvlVHCsaGvgRtGtlvaaylmlell.e.ggvdlleavkelrsqRpglavqnleqyrflyefllel
|
|||||||||
subfamily_PTPN5_RR_pd | Subfamily PTPN5_RR | 687-936 | 4.6e-50 | 165.2 | In-house | 25-270 (274) | alignment | ||
Range on Protein: 687-936
Range on HMM: 25-270/274.0
AVPVTSKPRSPVIQSPERTRVPIPPTSPTspsipsKPSDFFLDASFIRGYDSSHCSYIGATVSGGDSSTAFWRTVWEQQSRTIVCLCSPYELGK-VCPQY
..| | | |..|| . . |.. .. ...| .|.||| . |. . . ||| ....... || | | . | .|
vfgsqtknryktilPnensrvllesesse......dedssyinanyikGydeeskayvatqGPlpntvadfWrmiyqeevqvivmltklkeaneqkCavy
WPTKEGGPGTQLYGNILVTLKGGASGEHYFTSTLLIRNVEKslCRPVTHYWFSNWLDSEIPSSPQALMSMLLQVHNTHQES---YGPVVVHCSDGVGRTG
.|..|. .. ||.. .. .. . ..| .|.....|. .| |.|||...| | . | ....|....|.|.....|. .||||||| |.||||
fPdaedyeiserygdveikvekiverndysvrklvlkyler..ersvkhywytdWPdhksPddantlldlvleveesreeenaklapvvvhCsaGiGrtG
LVIATDINMQRLEESHTVDIPHTVSSIRQDRGQAILNIDQYAFIYRTLYEFSKF
||..| ...|.|...||. ..|. .|.||| . . .|| .|.|.|... |
cfiaisiavrqlreeivvdvlkivcnlrldrGGmvqtseqyelihralclylkr
|
|||||||||
subfamily_egg_pd | Subfamily egg | 691-940 | 3.1e-15 | 50.6 | In-house | 41-276 (307) | alignment | ||
Range on Protein: 691-940
Range on HMM: 41-276/307.0
TSKPRSPVIQSPERTRVPIpptsptspSIP-SKPSDFFLDASFIRGYdSSHCSYIGATVSGGDSSTAFWRTVWEQQSRTIVCLCSPYELgKVCPQYWPTK
| ||. .. . .|| . .. . .| |. | ..| .| | .. ||| |.... . || | | | . |. |||
lekarskrvhckdssrvkl........elrrGqylddfihanrvkGk.pllnefilaqaplkntvddfwrmvfqeevqyivmltsrkes.erceyywpka
EGGPGTQLYGNILVT-LKGGASGEHYFTSTLLIRnVEKSLCRPVTHYWFSNWLDSEIPSSPqalmsmlLQVHNTHQESYGPVVVHCSDGVGRTGLVIATD
| . . |.. .. || . |. | | | .| .. | || |.| .. ||||.. .|| ... ..| .
esdslvtvpGslrienlkvdskadplfrvtklkl.vGgddeerflehwqgdvnnssdvysp.......lrvlrklrnlskpvvvqdilGvskaatlvaie
INMQRLEESHTV--DIPHTVSSIRQDRGQAILNIDQYAFIYRTLYEFSKFLSSS
| . | .. . ..| .|. | .. . .| |.|| . | . . .|
iallsllrGpitkslvlravvflrlrrrlsvesvllylfvyrlvlfffrdvigs
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 692-931 | 2.2e-53 | 176.5 | Pfam-A | 3-234 (235) | alignment | ||
Range on Protein: 692-931
Range on HMM: 3-234/235.0
SKPRSPVIQSPERTRVPIpptsptspSIPSKPSDfFLDASFIRGYDsSHCSYIGATVSGGDSSTAFWRTVWEQQSRTIVCLCSPYELG-KVCPQYWPTKE
.| |.. | ..||| . . ..||| . |....||. .. ..| . .. ||| ||......||.|.| | | . |.||||..|
kknRykdilpydktrvkl........kgsegpsd.YInAnyvkgyk.ekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeee
GGpgTQLYGNILVTLK-GGA-SGEHYFTSTLLIRNVEKS-LCRPVTHYWFSNWLDSEIPSSPQALMSMLLQVHNTHQESYGPVVVHCSDGVGRTGLVIAT
.. .. ||.| |.|| ..| ...| ... ... | |..... || |...|.||..|.... .|....... ||||||||.|||||| ..|
ee..sltygdikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkvekskeaksgpvvVhCsaGvgRtgtfval
DINMQRLEESHTVDIPHTVSSIRQDRGQAILNIDQYAFIYRTLY
|| ...||. ..||. ..|...|. | ... ...||.|.|...
dilleqleaeeevdvlqivkelRkqRpgmvqsleqYiflykail
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 692-931 | 2.2e-53 | 176.5 | In-house | 3-234 (235) | alignment | ||
Range on Protein: 692-931
Range on HMM: 3-234/235.0
SKPRSPVIQSPERTRVPIpptsptspSIPSKPSDfFLDASFIRGYDsSHCSYIGATVSGGDSSTAFWRTVWEQQSRTIVCLCSPYELG-KVCPQYWPTKE
.| |.. | ..||| . . ..||| . |....||. .. ..| . .. ||| ||......||.|.| | | . |.||||..|
kknRykdilpydktrvkl........kgsegpsd.YInAnyvkgyk.ekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeee
GGpgTQLYGNILVTLK-GGA-SGEHYFTSTLLIRNVEKS-LCRPVTHYWFSNWLDSEIPSSPQALMSMLLQVHNTHQESYGPVVVHCSDGVGRTGLVIAT
.. .. ||.| |.|| ..| ...| ... ... | |..... || |...|.||..|.... .|....... ||||||||.|||||| ..|
ee..sltygdikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkvekskeaksgpvvVhCsaGvgRtgtfval
DINMQRLEESHTVDIPHTVSSIRQDRGQAILNIDQYAFIYRTLY
|| ...||. ..||. ..|...|. | ... ...||.|.|...
dilleqleaeeevdvlqivkelRkqRpgmvqsleqYiflykail
|
|||||||||
0042113 | (Phosphotyrosine protein) phosphatases II | 693-933 | 7.1e-50 | 165.1 | In-house | 12-242 (245) | alignment | ||
Range on Protein: 693-933
Range on HMM: 12-242/245.0
KPRSPVIQSPERTRVPIPPtsptspsIPSKPSDFFLDASFIRGYDSSHCSYIGATVSGGdSSTAFWRTVWEQQSRTIVCLCSPYELGKV-CPQYWPTkeg
| |.. | ..||| ..| ... . . . ||.. ||. .. .... . . . .||| .||....|||.|... |||.| |.||||.
knrysdilpydhtrvklsp.......dggdldsdyinasyvdgyritpkfiatqgPlpe.tvedfwrmlwelgittivmLteeeelgrvkcaqywpl...
gPGTQLYGNILVTLKGGASGEHYFTSTLLIRNVEKSLCRPVTHYWFSNWLDSEIPSSPQALMSMLLQVHNTHQ-ESYGPVVVHCSDGVGRTGLVIATDIN
... ||.. |||.. . ..| . || . |. .. | |.||.. .| | .|.... | ..| |.. . | |||.||||.||||||..|| ..
.gesltygdftvtllseehlddytvrtlevtnlgddesrevihyhylpwpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylm
MQRLEESHTVDIPHTVSSIRQDRGQAILNIDQYAFIYRTLYEF
...||. ..|.....| .|. |..|. . .|| |.|. |.|.
leqlekelgvsleeavkelrsqRpgavqtpsqyrflyeallel
|
|||||||||
0040439 | (Phosphotyrosine protein) phosphatases II | 693-933 | 1.7e-49 | 164.0 | In-house | 14-245 (249) | alignment | ||
Range on Protein: 693-933
Range on HMM: 14-245/249.0
KPRSPVIQSPERTRVPIPPtsptspsIPSKPSDFFLDASFIRGYDSSHCsYIGATVSGGDSSTAFWRTVWEQQSRTIVCLCSPYELGK-VCPQYWPTkeg
| |.| | ....|| . . .|. . . . .||.| ||.... .| . .. .||| .||.....||.|.|. |||. | ||||.
knrypdilpydhsrvklsi.......lpglflsdyinAsyidgyyikrr.fiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqywpl...
gPGTQLYGNILVTLKGGASGEHYFTSTLLIRNVEKSLCRPVTHYWFSNWLDSEIPSSPQALMSMLLQVHNTHQE--SYGPVVVHCSDGVGRTGLVIATDI
|.. ||.. |||. . ..| . || . |.... | |.|... .| | .|.|.. |.... .|.. ..| . |||.||||.||||||..|| ..
.ggsleygdftvtllsvevkddytvrtleltnlydgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtfiaayl
NMQRLEESHTVDIPHTVSSIRQDRGQAILNIDQYAFIYRTLYEF
...||. ..||....|. .|. |..|. | .|| |.|. |.|.
mleqlekelgvdleeavkllrsqRpgavqnpeqyrflyeallel
|
|||||||||
0037934 | (Phosphotyrosine protein) phosphatases II | 694-933 | 2.8e-45 | 150.1 | In-house | 14-241 (243) | alignment | ||
Range on Protein: 694-933
Range on HMM: 14-241/243.0
PRSPVIQSPERTRVPIpptsptspsipskPSDFFLDASFIRGYDsshcSYIGATVSGGDSSTA----FWRTVWEQQSRTIVCLCSPYELGKV-CPQYWPt
| . | ...|| . ... ...|..|.... .| . .. ||| .||.....||.|....|||.. |.||||
nrysdilpydhsrvkl.............egsdyinanliyvtp....rliatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqywp.
keggpGTQLYGNILVTLKGGASGEHYFTSTLLIRNVE-KSLCRPVTHYWFSNWLDSEIPSSPQALMSMLLQVHNTHQE--------SYGPVVVHCSDGVG
|.. ||.. |||.. ....| |||..|.. . |.| |.||.. .| | .|.||. |...| .|.. .| | |||.|||| |||
.....gevtygdftvtllseehlddytvrtlllenldlddltrlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvg
RTGLVIATDINMQRLeeshTVDIPHTVSSIRQDRGQ-AILNIDQYAFIYRTLYEF
|||..|| .. ...| .||. ..| .|. |.. |. . .|| |.|. |.|.
RtGtliaaylmllll....gvdleeavkllreqRpgkavqtpsqyrflyeallel
|
|||||||||
subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 695-932 | 1.5e-38 | 127.6 | In-house | 46-274 (281) | alignment | ||
Range on Protein: 695-932
Range on HMM: 46-274/281.0
RSPVIQSPERTRVPIPPTSPTSpsipskPSDfFLDASFIRGYDSShCSYIGATVSGGDSSTAFWRTVWEQQSRTIVCLCSPYELGKV-CPQYWPTKEGgp
| | . . ||| . |.. .. .| ...|.|. ||.. || . .| .|||. ||||. ..|| . | ||. | .||| ..
rYsnivaYDatrvkvtpneenk......ntD.Yinanfvpgykge.keyiatqgPvPaslvafWqmvweqkvsaivmvtreieagklkChrYWPddns..
gTQLYGNILVTLKGGASGEHYFTSTLLIrNVEKSLCRPVTHYWFSNWLDSEIPSSPQALMSMLLQVHNTHQESY-GPVVVHCSDGVGRTGLVIATDINMQ
. ||.. |. . .. ..| . .. . . |.. | |.. . .| | .|.....|.. .|....... |.|.||| |||||| || | ..
.elkygdvtvkstaeeekatyierkfkl.eresgetreveqlaytaWPdhGvPattkellefrkevlkltekktkaplvihCsaGvGrtGtyialDrlvk
RLEES-HTVDIPHTVSSIRQDRGQAILNIDQYAFIYRTLYE
..|.. ...|. .| ..|..| . . ||.|.|... .
aveaeleeldvkavvaelrkernlmvqtvvqyefvykavld
|
|||||||||
subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 705-937 | 9.3e-49 | 160.8 | In-house | 35-267 (270) | alignment | ||
Range on Protein: 705-937
Range on HMM: 35-267/270.0
TRVPIpptsptsPSIPSKPSDFFLDASFIRGYDSSHCSYIGATVSGGDSSTAFWRTVWEQQSRTIVCLCSPYELGK-VCPQYWPTKEGGPGTQLYGNILV
||| . ... ... .. | ..||.|.....|| | . ..|||..||.....|| . | |. | .|||.. . . .|.| |
tRvrl.......eeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpaepkekvkledgkikv
TLKGGASGEHYFTSTLLIRnvEKSLCRPVTHYWFSNWLDSEIPSSPQ------ALMSMLLQVHNTHQES--YGPVVVHCSDGVGRTGLVIATDINMQRLE
. . | | . | .. ||. | ..|.|. .| | .|.... |..|| .|.....| .|..||||.||||||..||.|| .. ||
lalseekeegyiltrlrle..ekgeerrlvHfwyntWpdhgvpreedsslstdqllkmlravrrsekeldkaePllvHcsaGvgRtGtlialDiavrlLe
ESHTVDIPHTVSSIRQDRGQAILNIDQYAFIYRTLYEFSKFL
|.. ||. . .. .|.|| . . .||.|.|... |. ...
etkkvdvlaiieelRkdRmalvqhpeqyeflykavveyaerr
|
|||||||||
subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 706-932 | 5.5e-31 | 102.6 | In-house | 63-276 (287) | alignment | ||
Range on Protein: 706-932
Range on HMM: 63-276/287.0
RVPIPptsptspsipSKPSDfFLDASFIRGYDSsHCSYIGATVSGGDSSTAFWRTVWEQQSRTIVCLCSPYELG-KVCPQYWPTKEGgpgtQLYGNILVT
||.. . | ...|.|| || . . .| | . ||. ..... .|| || | .|| ||||... ..|. ..
rvllk..........gehpd.yinavfidgyke.kkafiiaesPmfntarnfWkliddrnvtaivmlcqekendeevcyqyWpeeks....vvlGeynie
LKGGASGEHYFTSTLLIRNVEK-SLCRPVTHYWFSNWLDSE-IPSSPQALMSMLLQVHNTHQESYGPVVVHCSDGVGRTGLVIATDINMQRLEESHTVDI
| ..| .| ..| .| . . |. | . || . ... |. . .... .... ...||||||.|||... .| .. ... .. ..|.
llneevnagyierklevknknkagdkqqvkqyqitnWdstgkvtepqtillvieemyktqrkrgntsivvhCsdtvGrsamfcaaattinkckteGviDv
PHTVSSIRQDRGQAILNIDQYAFIYRTLYE
. | |. . ... ..|| ||. . |
fqvlksqriqkpgsvqtveqykfindivle
|
|||||||||
0044763 | (Phosphotyrosine protein) phosphatases II | 710-929 | 6.1e-27 | 89.8 | In-house | 3-166 (178) | alignment | ||
Range on Protein: 710-929
Range on HMM: 3-166/178.0
PPTSPTSPSIPSKPSDFFLDASFIRGYdsshcSYIGATVSggdssTAFWRTVWEQQSRTIVCLCSPYELG-KVCPQYWPTKEGgpgtqlygnilvtlkgg
..| .... .. ....||.| .. |.|. . .... ..|. ..||.|....||| |..|||...|
drtrvllsnleglersdyinaseilpg.....lylgslpp.....addlellkelgithivnlteelelgflkcdpywpeeag.................
asgehyftstllirnvekslcrpvTHYWFSNWLDSEIPSSPQALMSMLLQVHNTHQESYGPVVVHCSDGVGRTGLVIATDINMQRleeshTVDIPHTVSS
.| . .. |. |.... .. .. ... ..|. |||.|||| ||||.|...| .. ... ..... ..
........................iqylhipipDhgvpdllehflefvefieealdekggpvlVHCsaGvgRsgtlvaaylmkkl.....glsleeaiel
IRQDRGqAILNIDQYAFIYRT
.|. | .. | .|. ..|.
vrerRp.ivpnpgqlrqLyef
|
|||||||||
0049772 | (Phosphotyrosine protein) phosphatases II | 716-937 | 1.3e-20 | 69.8 | In-house | 64-283 (314) | alignment | ||
Range on Protein: 716-937
Range on HMM: 64-283/314.0
SPSIPSKPSDfFLDASFIRGYdsshCSYIGATVSGGDSSTAF----------WRTV--WEQQSRTIVC---------------------LCSPYELGkvc
|. | . || . .||...|. ...| . | || | .....|.||. |... ..|
lpglpvsgsd.yinasyvdgf....lkfIatqgpleitvvdfreepvlyyngwrmvlrgdlnvrdivmsrdevladelsrLdaAlgKtpllildgng...
pqywptkeggpgT----------QlygnilvtlkggasgehyftstllirNVE---KSLCRPVTHYWFSNWLDSEIPsSPQALMSMLLQVHNThqESYGP
. .. . . |.. .|. .. | . | ... . ..| ... . ||
............neptaadlellk..........................eelydpelferlgikylripvpDgsap.lledfdeflefieea..dkggp
VVVHCSDGVGRTG--LVIATDINMQrleeshTVDIPHTVSSIRQDRG-----QAILNIDQYAFIYRTLYEFSKFL
|.|||..|.|||| .|.| . . |.. ... .|. | .| . .|| ||.. |.|. |||
vlvHCkaGkgRtgtfvvaaylmkll......gvsleealedvrlkRpinpnpgfieqleqyefilealleylkfl
|
|||||||||
subfamily_PTPRK_pd | Subfamily PTPRK | 718-932 | 5.1e-36 | 119.1 | In-house | 64-275 (314) | alignment | ||
Range on Protein: 718-932
Range on HMM: 64-275/314.0
SIPSKPSDFFLDASFIRGYDSSHcSYIGATVSGGDSSTAFWRTVWEQQSRTIVCLCSPYELGKV-CPQYWPTKeggpgTQLYGNILVTLKGGASGEHYFT
.| || ...|..| .| .. .| . . . ||| |..... .|| | | |.| | .||| . |. ||.| |.| . . .
tidgdpssdyinaalidsykrpa.afivtqgPlqetvkdfWrlvydencasivmltelvevgrvkClkyWPed.....tevygdikvelvetellaelvv
STLLIRNVEK--SLCRPVTHYWFSNWLDSEIPSSPQALMSMLLQVHNTHQESYGPVVVHCSDGVGRTGLVIATDINMQRLEESHTVDIPHTVSSIRQDRG
.. ...... . | | .. | .| | ..| | ..|.... .|.....|. |..||||| | |||| || || .. .|. ..||. ..| ..|. .
rifrveklargqeeirevrqfqflgWpdhdvPvsatgllklvrrvkksqeeeaGrivvhCsaGaGrtGtfiaidivldmieregvvdvfnavktlrsrkv
QAILNIDQYAFIYRTLYE
. .|| ||| . |
nmveteeqykfiydvile
|
|||||||||
subfamily_Sponge-PTP6_pd | Subfamily Sponge-PTP6 | 718-936 | 9.1e-33 | 108.3 | In-house | 69-281 (439) | alignment | ||
Range on Protein: 718-936
Range on HMM: 69-281/439.0
SIPSKPSDFFLDASFIRGYDSSHcSYIGATVSGGDSSTAFWRTVWEQQSRTIVCLCSPYELGKvcpqYWPTKEggpgTQLYGNILVTLKGGASGEHYFTS
|| | ...| .|.|| . || . . ... ||| |.|... ||| |. | | |||... ||.| | .|
eipgvphshyinanyikGyyddk.lyiatqgpkkettddfwrlviekktvtivmltnlvesyk....ywpsda....evcygdiavrvdrnielpnyvir
TLLIRNVE--KSLCRPVTHYWFSNWLDSEIPSSPQALMSMLLQVHNT-HQESYGPVVVHCSDGVGRTGLVIATDINMQRLEESHTVDIPHTVSSIRQDRG
. . | | | .. . | | ..|. .. .| . . .| ||||||||| |||||| .|| || ...| ||| |. .|..|
gfkvfnerdttekertvlqfhyiawpdknvpaqashvldflrainsandkeeygpvvvhcsagvGrtGtiialdialeqlklenkvdikgivkvlrkqrk
QAILNIDQYAFIYRTLYEFSKF
| . .. || ||| .. | ..
qmvqalcqyvfiynavledivy
|
|||||||||
subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 719-932 | 3.3e-37 | 122.8 | In-house | 65-274 (515) | alignment | ||
Range on Protein: 719-932
Range on HMM: 65-274/515.0
IPSKPSDFFLDASFIRGYDSSHcSYIGATVSGGDSSTAFWRTVWEQQSRTIVCLCSPYELGKV-CPQYWPTKEGGpgTQLYGNILVTLKGGASGEHYFTS
| .| ...||.|...|. . .|| . | ||| |.... ||. . | |. | .||| | | . .|.| | | .
indnPhsdyfnasyipsfdndk.ayiasqgPnkasvddfWrlvlqenvttiamvtklkegdkikcgkyWPdkpgd..svkfGsikvelvsleactggikr
TLLIRNVEKslCRPVTHYWFSNWLDSEIPSSPQALMSMLLQVHNTHQESYGPVVVHCSDGVGRTGLVIATDINMQRLEESHTVDIPHTVSSIRQDRGQAI
.| . .. .| || . | .| | .| ..|. .. .| |.. |...||| ||||||.||. | . . .....||. ..| |||.| . .
kltvlkgdd..srtvtqfhfteWPdkGvpkhtssllklikevkadhgqythpliihcsaGvGrtGvvisidsvvahakttrmvdvfnfvtnirqkrpylv
LNIDQYAFIYRTLYE
.|||||| .. |
qtqeqyafiygavle
|
|||||||||
subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 719-933 | 2.3e-36 | 120.2 | In-house | 66-276 (315) | alignment | ||
Range on Protein: 719-933
Range on HMM: 66-276/315.0
IPSKPSDFFLDASFIRGYDSSHcSYIGATVSGGDSSTAFWRTVWEQQSRTIVCLCSPYELGK-VCPQYWPTKEGGpgTQLYGNILVTLKGGASGEHYFTS
| .| . ...||.|...|. . .|| . | ||| |.... ||| . | | | |||| ... . .|.| |.| . .
iddsPdsdyinasyiksvdddk.ayiasqgPlkasvddfwrmvlqekvttivmvtkkqegdkikcrqywPdrkad..svefGsikvellsleadtdgvar
TLLIRNVEKSlcRPVTHYWFSNWLDSEIPSSPQALMSMLLQVHNTHQESYGPVVVHCSDGVGRTGLVIATDINMQRLEESHTVDIPHTVSSIRQDRGQAI
| .|. |.| | || . | .| | .. .|. .. .| ... ...|||| ||||||.||. | .........||. ..| .|..| . .
klvtrksees..rtvtqfqftewPdkGvdkqtssllklikevkadngkkefsllvhcsaGvGrtGvvisidevvaqikrtrsvdvfnfvknlrakrpylv
LNIDQYAFIYRTLYEF
..||||| .. |
qteeeyafiydavled
|
|||||||||
subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 719-933 | 1.4e-34 | 114.6 | In-house | 73-283 (297) | alignment | ||
Range on Protein: 719-933
Range on HMM: 73-283/297.0
IPSKPSDFFLDASFIRGYDSshcSYIGATVSGGDSSTAFWRTVWEQQSRTIVCLCSPYELGKVCPQYWPTKeggpGTQLYGNILVTLKGGASGEHYFTST
. ..|. ...|||..|. .| . .. ||. |...| ||| | | | | .||. | |.. .|.. |.|. .. | . .
vnddpdsDyvnasfvkgnkh...rlittqmPmkatvadfWamvldeqvstivmlnddnerdkkcaryWsdk....gvttfGdvsvvllsvsereGfikre
LLIRNVEKSLCRPVTHYWFSNWLDSEIPS--SPQALMSMLLQVHNTHQES-YGPVVVHCSDGVGRTGLVIATDINMQRLEESHTVDIPHTVSSIRQDRGQ
| ... . | | | | .| | ... | ..|. .. .|...... ||..|||. ||||||.... | . . .. ..||| .|. .||.| .
levtkgkakarrvvkqyqfveWPdkaverkdsassllklisevrkdfsqnaegPllvhclaGvGrtgvlltidsvvaeakrekevdifglvkklrqerpy
AILNIDQYAFIYRTLYEF
. .||.|.| .. |.
lvqtkeqykfvyvavlea
|
|||||||||
subfamily_PTPN9_pd | Subfamily PTPN9 | 721-935 | 5.8e-41 | 135.5 | In-house | 67-291 (297) | alignment | ||
Range on Protein: 721-935
Range on HMM: 67-291/297.0
SKPSDfFLDASFIRGYDSsHCSYIGATVSGGDSSTAFWRTVWEQQSRTIVCLCSPYELGKV-CPQYWPTKEGGpgTQLYGNILVTLKGGASGEHYFTSTL
. || ...|.|. || . ..|.. . .. ||| ||||. ..|| | |.. | ||||..|. .. .|.. |. . |.| ...|
deasd.yinanfvdGykq.kkafiatqGplkktvsdfWrmvWeqevlvivmttrvvergrlkcgqyWpleees..saefgdlsvsnveveeeedykvrvl
LIRNVEKSLCRPVTHYWFSNWLDSEIPSSPQALMSMLLQVHNTH-------------QESYGPVVVHCSDGVGRTGLVIATDINMQRLEESHTVDIPHTV
|.||... | |||. | | | .||| ..|. .| .| .. . | |.||||| |.|||| |. ||...|||| |||. .||
eiknvkteesrkvthfqflsWPdyGvPssaaslldvlekvrekqalavkelgdewkghpsgPPivvhcsaGiGrtGtfitldiclsrleevgtvdvvetv
SSIRQDRGQAILNIDQYAFIYRTLYEFSK
. .|. | .| .||.| | .. |...
kllrtqrafsiqtpeqyefcylavleyal
|
|||||||||
subfamily_CG7180_pd | Subfamily CG7180 | 721-933 | 1.2e-32 | 107.8 | In-house | 66-289 (296) | alignment | ||
Range on Protein: 721-933
Range on HMM: 66-289/296.0
SKPSDFFLDASFIRGYDSSHcSYIGATVSGGDSSTAFWRTVWEQQSRTIVCLCSPYELGKVCPQYWPTKEggpgTQLYGNILVTLKGGASGEHYFTSTLL
. .. ...|... .. . || .. .||| |..... ..| |. . . | .|.||| | . ||.|.| . . . . |.
GeeksdYinavyvdsflkkk.eyivteapkketvdefWrlvydeeisavvvLtktfdfakmypsywpnks....keqygeifveiveekqyanlkirtfk
IRNV----------EKSLCRPVTHYWFSNWLD-SEIPSSPQALMSMLLQVHNTHQ-----ESYGPVVVHCSDGVGRTGLVIATDINMQRLEESHTVDIPH
. .| | |... . | ..|.| .||. .. .|. . . .|||||..|||..|.| .| |.|.. .|. . ||. .
ltkkivalteqekqvkaetRivklfqlteWeledkvPlstnalielrrrvrlwrekvdedpeegPvvvvssdGasRsGvylaidanlelvekeeevdvFe
TVSSIRQDRGQAILNIDQYAFIYRTLYEF
| .|..| | . |...| .|| .| |.
avktlrrsRpqLvenveeYkyiYdvllea
|
|||||||||
subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 722-934 | 1.7e-48 | 160.3 | In-house | 72-280 (318) | alignment | ||
Range on Protein: 722-934
Range on HMM: 72-280/318.0
KPSDfFLDASFIRGYDSSHcSYIGATVSGGDSSTAFWRTVWEQQSRTIVCLCSPYELGKV-CPQYWPTKeggpGTQLYGNILVTLKGGASGEHYFTSTLL
. || ...|..| || ... .|| | . . ||| ||||.|..|| | | ||. . .||| | |.. ||.. |.|| . ..| ..
egsD.yinanyidGyrrkk.ayiaaqaPlpetieDfWrmvWeqnsavivmltqeeergkakvhryWPsk....gsrsygklvvelkeevelsdyvlrefk
IRNVEKSLCRPVTHYWFSNWLDSEIPSSPQALMSMLLQVHNTH-QESYGPVVVHCSDGVGRTGLVIATDINMQRLEESHTVDIPHTVSSIRQDRGQAILN
... |.. | | | . .| |. .|.|. |.... ||.... ....||.||||| |||||| || || ..|... .||. .||. .|. | .
vtrteeeesrqvrqyhytsWpdegvpesgaslldlvrqvskaqqksgagpivvhCsaGvGrtGvfiavdillerikaealvDvfqtvkqlreqrnlmvqt
IDQYAFIYRTLYEFS
||| ||| .| |.
edqyefiydvlleal
|
|||||||||
subfamily_PTPRB_pd | Subfamily PTPRB | 722-933 | 3.6e-45 | 149.2 | In-house | 76-284 (293) | alignment | ||
Range on Protein: 722-933
Range on HMM: 76-284/293.0
KPSDFFLDASFIRGYDSSHcSYIGATVSGGDSSTAFWRTVWEQQSRTIVCLCSPYELGKV-CPQYWPTKEGgpgTQLYGNILVTLKGGASGEHYFTSTLL
.... ...|..|.|| | . .| . .. ||| |||..|..|| | | ||| | .|||..| ..|||.| |||. . |.. . .|.
esgsDYinanyipgynspr.efiatqGPlpetvddfWrmvwekkssiivmltqlvekgkvkCeeYWPadee...pvlyGdikvtlvaeeeledwvirelk
IRNveKSLCRPVTHYWFSNWLDSEIPSSPQALMSMLLQVHNTH--QESYGPVVVHCSDGVGRTGLVIATDINMQRLEESHTVDIPHTVSSIRQDRGQAIL
|.. .. .| |..| | | | ..|.....|.... .|.... ..| .|.||||| |||||| || | .|..||. .||| .|...|..| . .
iek..ekeerkvrqyhftsWpdhgvPektktlldfvrtvreaiektaskrPivvhCsaGvGRtGtfialdrllqaieeedyvdifgivaelReeRnllvq
NIDQYAFIYRTLYEF
. .|| ||.... ..
tekqYifihqcvldl
|
|||||||||
subfamily_PTPRN_pd | Subfamily PTPRN | 722-930 | 2.8e-33 | 109.9 | In-house | 81-288 (297) | alignment | ||
Range on Protein: 722-930
Range on HMM: 81-288/297.0
KPSDFFLDASFIRGYDSSHCSYIGATVSGGDSSTAFWRTVWEQQSRTIVCLCSPYELG-KVCPQYWPTkEggpGTQLYGNILVTLKG-GASGEHYFTSTL
. ......||.| | . .|| . .. ..||..|||| . || |.. | | | | .||| | |...|. | | . |. ..
aeksdyinasaildhdprapayiatqgplastvadfwqmvweqGvvvivnltrleeegvkqckrywpd.e...Gsevyhiyevhlvsehiwcddylvrsf
LIRNVEKSLCRPVTHYWFSNWLDSEIPSSPQALMSMLLQVHNTHQESYGPVVVHCSDGVGRTGLVIATDINMQRLEE-SHTVDIPHTVSSIRQDRGQAIL
..|...| | || . | | ....|.|...|. . .| ... |.|||||||.|||| |. |. ..|| . .|| |. .|..| . .
ylknlqtsetrtvtqfhflswpeegvPasaksllefrrkvnksyrGrscpivvhcsdGaGrtGvyilidlvlnrllkGvkeidiaatlehlrdqrpglvk
NIDQYAFIYRTL
||. |.. ..
tkdqfefaltav
|
|||||||||
subfamily_Sponge-PTP5_pd | Subfamily Sponge-PTP5 | 722-931 | 2.3e-31 | 103.7 | In-house | 55-263 (283) | alignment | ||
Range on Protein: 722-931
Range on HMM: 55-263/283.0
KPSdFFLDASFIR--GYDSSHCSYIGATVSGGDSSTAFWRTVWEQQSRTIVCLCSPYE-LGKVCPQYWPTKeggpGTQLYGNILVTLKGGASGEHYFTST
.. ...|.|| . || | . ||. |.... .|| | | | . | |||| . |.. ||. |||. . . .
esr.dyinavfipvsksykqdkkyiiaqsPldrtvvdfWkmvfdekitaivmltklqedlrikCsqyWPkr....GsedyGeftvtlrkettsnsfiike
LLIRNV---EKSLCrpVTHYWFSNWLDSEIPSSPQALMSMLLQVHNTHQESYGPVVVHCSDGVGRTGLVIATDINMQRLEESHTVDIPHTVSSIRQDRGQ
||.|. ...| ..|| . .||. . . .|. . . . . .. ||.||||| |.|||. || .. . . ||.. .| .|..|
lllrvnssakstll..lahyqvidWleygeqaiinslvkfnkvislqteskkgPivvhCstgiGrtavfiaasasvkdaltesvvdvfavvkimreqrmm
AILNIDQYAFIYRTLY
|. . ||| ...
avqtldqyklvhelvl
|
|||||||||
subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 722-933 | 2.5e-28 | 94.2 | In-house | 73-287 (325) | alignment | ||
Range on Protein: 722-933
Range on HMM: 73-287/325.0
KPSDFFLDASFIRGYdSSHCSYIGATVSGGDSSTAFWRTVWEQQSRTIVCLCSPYELGKVCPQYWPTKEGGpgTQLYGNILVTLKGGASGEHYFTSTLLI
.|| ...||..| . .. | . .. .|| | . .. .| | . . | .||| . | .. .| . | |. | | .
dpssdyinasylrdd.kkkdvflaaqaPltatindlWrlvldWrcsvvvvlneldlgkdrcavywpkemgk..sktfGglevklrtieeisdyvhrvldv
RNVEKSLCRPVTHYWFSNWLDSEIPSSPQALMSMLLQVHNTHQ------ESYGPVVVHCSDGVGRTGLVIATDINMQRLEESHTVDIPHTVSSIRQDRGQ
..|.| | | . . | | . | .|.|.| |.. .. .. .|..||||.|||||| |. .... | ||| | .|.|| .
kqvkkGetrsvkqfqlqswddmGvqkrpatlisilqlvkavservtantkastpilvhcsaGvGrtGvfislysalakvieesrvdifgfvkklrkdrps
AILNIDQYAFIYRTLYEF
. .||| .|| .| |.
mvetvdqyiliyealvea
|
|||||||||
subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 723-930 | 2.2e-30 | 100.6 | In-house | 33-236 (239) | alignment | ||
Range on Protein: 723-930
Range on HMM: 33-236/239.0
PSDFFLDASFIRGYDSSHCSYIGATVSGGDSSTAFWRTVWEQQSRTIVCLCSPYEL-GKVCPQYWPTKeggpgTQLYGNILVTLKGGASGEHYFTSTLLI
| ...||..| || | .|| . . || ||| .|... || | | | | |||| | | |. |||. | |...
phsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpds.....tskycnlrvtlrktevfadyiirtfvm
RNVEKSLCRPVTHYWFSNWLDSEIPSSPQALMSMLLQVHNTHQESYGPVVVHCSDGVGRTGLVIATDINMQRLEESHTVDIPHTVSSIRQDRGQAILNID
.| .. | | .| |. | | .| |.. . .. . | |.||| |||||| .. | ... .. .|||| | .||.|| . . .
sqvgqteeryvyqyhftvwpdkgvpqyatavlglrrkitkdslpgarpwvihcsagvgrtgaflvidamlrqakkqktvdifnyvkairedrphmvqtse
QYAFIYRTL
|| ||. ..
qyvfihlav
|
|||||||||
subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 723-930 | 2.6e-30 | 100.4 | In-house | 34-237 (239) | alignment | ||
Range on Protein: 723-930
Range on HMM: 34-237/239.0
PSDFFLDASFIRGYDSSHCSYIGATVSGGDSSTAFWRTVWEQQSRTIVCLCSPYEL-GKVCPQYWPTKeggpgTQLYGNILVTLKGGASGEHYFTSTLLI
| ...||..| || | .|| . . || ||| .|... || | | | | |||| | | |. |||. | |...
phsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpds.....tskycnlrvtlrktevfadyiirtfvm
RNVEKSLCRPVTHYWFSNWLDSEIPSSPQALMSMLLQVHNTHQESYGPVVVHCSDGVGRTGLVIATDINMQRLEESHTVDIPHTVSSIRQDRGQAILNID
.| .. | | .| |. | | .| |.. . .. . | |.||| |||||| .. | ... .. .|||| | .||.|| . . .
sqvgqteeryvyqyhftvwpdkgvpqyatavlglrrkitkdslpgarpwvihcsagvgrtgaflvidamlrqakkqktvdifnyvkairedrphmvqtse
QYAFIYRTL
|| ||. ..
qyvfihlav
|
|||||||||
subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 724-933 | 1.2e-42 | 140.9 | In-house | 37-241 (250) | alignment | ||
Range on Protein: 724-933
Range on HMM: 37-241/250.0
SDfFLDASFIRGYDSShCSYIGATVSGGDSSTAFWRTVWEQQSRTIVCLCSPYELGKVCPQYWPTKEggpgTQLYGNILVTLKGGASGEHYFTSTLLIRN
|| ...|||. ||| . ..| . .. ||| |.|..| ||| | . | .|...||||... .. ||...|.|. | . .| . .
sd.yinasflhgyder.kafiatqgPlqatiedfWrmvleeksgtivmLtnLkesektyhqywPvek....aekyGdvtvsllskeefadytkrklklsk
VEKSLCRPVTHYWFSNWLDSEIPSSPQALMSMLLQVHNTHQE-SYGPVVVHCSDGVGRTGLVIATDINMQRLEESHTVDIPHTVSSIRQDRGQAILNIDQ
.|. | | .. | .| | .| .| . .| .|. ..|. .||.|.|| ||||.| || | ..||.....||. . . .|.|| .|. .|
akkaderivrqlhfvvWPdkgvPevatavLellkkvqasqqqagnaPvivqCsaGvgrsGafiaidavlerlkkekvvdvfkvikvlrkdrphavesleq
YAFIYRTLYEF
| |.|. . ..
yvfvyeiilka
|
|||||||||
subfamily_PTPN12_pd | Subfamily PTPN12 | 724-933 | 9.1e-38 | 124.8 | In-house | 67-276 (290) | alignment | ||
Range on Protein: 724-933
Range on HMM: 67-276/290.0
SDFFLDASFIRGYDSsHCSYIGATVSGGDSSTAFWRTVWEQQSRTIVCLCSPYELGKV-CPQYWPTKEGgpGTQLYGNILVTLKGGAS-GEHYFTSTLLI
. ...|.||.| .. ...|| | . . ||| .||.. . .| .| .|||| | .||| . . . .|.. |||. . .. || .
gsdYinanfikgveg.kleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkkCerYWpeege..eelefgefevtleeekavdddflirtLkv
RNVekSLCRPVTHYWFSNWLDSEIPSSPQALMSMLLQVHNTHQESYGPVVVHCSDGVGRTGLVIATDINMQRLEESHT---VDIPHTVSSIRQDRGQAIL
.. . .| |. . . .| | ..|||.. |.... .|....... |.||||| |||||| .|| |. . |.. .. .|. . | ..|..| ..
eaq..kesrkvyqfhYtaWPDhgvPssaksllelielvrelqesedaPlvvhCsaGvGrtGtiiaidyvrellkaekipeeldvfdlvlelrkqraalvq
NIDQYAFIYRTLYEF
.|| ..|... |.
tkeqyelvykavael
|
|||||||||
subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 724-936 | 1.4e-36 | 121.5 | In-house | 89-293 (319) | alignment | ||
Range on Protein: 724-936
Range on HMM: 89-293/319.0
SDfFLDASFIRGYDSSHcSYIGATVSGGDSSTAFWRTVWEQQSRTIVCLCspyelGKVCPQYWPTKeggpGTQLYGNILVTLKGGASGEHYFTSTLLIRN
|| ...|||. || . || | .. ||| .||... ||| | . | |||| | . . ... | .. . | . . .
sd.yinasfvtGyqrkd.kyiaaqGPldntladfWrmiweyncstivllt.....kdkcsqywplk....ivikeerfkvkvdsveetaeyvvrdielse
-VEKSLCRPVTHYWFSNWLDSEIPSSPQALMSMLLQVHNTHQES--YGPVVVHCSDGVGRTGLVIATDINMQRLEESHTVDIPHTVSSIRQDRGQAILNI
.. | .| . | | | | .| || .. .|. .. ..||||| |||||| |. |. ..|..| . ||. ..| .||.| . . ..
dgkekdirkitqfhflGwpdvGvpdypsdlmrlvkkvrhltskenhranivvhcsaGvGrtGvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdl
DQYAFIYRTLYEFSKF
|| ||| .| | |
vqykfiysalleehlf
|
|||||||||
subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 724-936 | 2.7e-36 | 120.5 | In-house | 53-257 (284) | alignment | ||
Range on Protein: 724-936
Range on HMM: 53-257/284.0
SDfFLDASFIRGYDSSHcSYIGATVSGGDSSTAFWRTVWEQQSRTIVCLCspyelGKVCPQYWPTKeggpGTQLYGNILVTLKGGASGEHYFTSTLLIRN
|| ...|||| || . . || . .. ||| .||... ||| | . | |||| | . . ... | .. | | . . .
sd.yinasfitGyqrkd.kyiatqGPldntladfWrmiweyncstivllt.....kdkcsqywplk....ivikeerfkvkvdsveeseeyvvrdielse
-VEKSLCRPVTHYWFSNWLDSEIPSSPQALMSMLLQVHNTHQES--YGPVVVHCSDGVGRTGLVIATDINMQRLEESHTVDIPHTVSSIRQDRGQAILNI
.. | .. . | | | | .| || .. .|. .. ..||||| |||||| |. |. ..|..| . ||. ..| .||.| . . ..
dgkekdirkirqfhflgwpdvgvpdypsdlmrlvkkvrhltskenhranivvhcsagvgrtgvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdl
DQYAFIYRTLYEFSKF
|| ||| .| | |
vqykfiysalleehlf
|
|||||||||
subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 725-933 | 2.3e-47 | 156.5 | In-house | 75-278 (288) | alignment | ||
Range on Protein: 725-933
Range on HMM: 75-278/288.0
DFFLDASFIRGYDSSHcSYIGATVSGGDSSTAFWRTVWEQQSRTIVCLCSPYELGK-VCPQYWPTKEGgpgTQLYGNILVTLKGGASGEHYFTSTLLIRn
...||.| |..... || . |. ||. |.|... ||| | . | || | .|||... ..||.. |||.. |.. . .||.
aDYinasyidgekkkk.kyiatqgPladtvndfWelvyenktstivmltelveggktkCeeYWPdadk...pknyGsvtvtlveskeledfvlrkllle.
vEKSLCRPVTHYWFSNWLDSEIPSSPQALMSMLLQVHNTHQESYGPVVVHCSDGVGRTGLVIATDINMQRLEESHTVDIPHTVSSIRQDRGQAILNIDQY
| . .|.| . | | ..| | . |. .| ||....|. ||..||||.|||||| || | ....||. ..|. ||. .|. | . . . ||
.kkkteleitqyqylaWpdhgvPeskapllellrqvkvanqadtgpiivhCsaGvGrtgtFialdalidaveeedyiDvagtvaklRkqRallvqtlkqY
AFIYRTLYEF
|||..| .
efiyevllsl
|
|||||||||
subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 725-935 | 6.7e-19 | 62.9 | In-house | 58-260 (267) | alignment | ||
Range on Protein: 725-935
Range on HMM: 58-260/267.0
DfFLDASFIRGYDSSHcSYIGATVSGGDSSTAFWrTVWEQQSRTIVCLCSPYELGKVcPQYWPTKEGGpgTQLYGNILVTLKGGASGEHYFTSTLLIRNV
. ...||.. || . .| . . | |. ||. .| ... | . ... ...|| | | .. | .. | . | || ..
e.yinasyvegyktkn.afivtqdplkntitdfl.tvihdqkvpvivlltkvftdni.rlfwPPkmgq..akkyqdltvehslekeendyqiitlelkfk
EKSlCRPVTHYWFSNWlDSEIPSSPQALMSMLLQVHNTHQESYGPVVVHCSDGVGRTGLVIATDINMQRLEESHTVDIPHTVSSIRQDRGQAILNIDQYA
..| .. || |.. .| . . | . . .| .. |.||.|||||||.| . | ..|. . ..|| . . ||. | . ..|
nes.ahnvtlyyykkw.nintnnkpylkplfgilaknqlengnrPlvvacsdGvGrsGtflvidsqleraktegvsdifdflrkirsqriglvdtkeryi
FIYRTLYEFSK
.|...| |...
yihellaeyae
|
|||||||||
subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 726-932 | 4.4e-35 | 116.0 | In-house | 77-281 (290) | alignment | ||
Range on Protein: 726-932
Range on HMM: 77-281/290.0
FFLDASFIRGYDSSHcSYIGATVSGGDSSTAFWRTVWEQQSRTIVCLCSPYELGK-VCPQYWPTKeggpGTQLYGNILVTLKGGASGEHYFTSTLLIRNV
...|..| || .. .|| . . ||. .|.... || |.. | || .| ||||.. .|. ||.. ..| . ..| . .| ..|
eyinAcyikgykekk.qyiatqgpvsntlvdFWkliwqekvtiivmltniieegkvkCqqYWpds....dtkaygefsikllneetlneyierklevknk
EK-SLCRPVTHYWFSNWLDSE-IPSSPQALMSMLLQVHNTHQESYGPVVVHCSDGVGRTGLVIATDINMQRLEESHTVDIPHTVSSIRQDRGQAILNIDQ
.. .. ||.| ..|| . . .. |... .... ... ...||||||.|||... .|... ... . .|. . . | |. . . . .|
nsagakqsvtqyqitnwdstgkvtnpqtillvieemyktqrkrgntsivvHCSdtvgrsavfcaaattinkcktegvidvfqvlksqRiqkpgsvqtvqq
YAFIYRTLYE
| .|.. . .
yqgifqivlt
|
|||||||||
subfamily_PTPRD_pd | Subfamily PTPRD | 727-937 | 1.5e-57 | 190.5 | In-house | 78-284 (564) | alignment | ||
Range on Protein: 727-937
Range on HMM: 78-284/564.0
FLDASFIRGYDsSHCSYIGATVSGGDSSTAFWRTVWEQQSRTIVCLCSPYELGK-VCPQYWPTKegGpgTQLYGNILVTLKGGASGEHYFTSTLLIRNVE
. |||| ||. .. .|| . .. ||| ||||.|.||| | . | || | .|||.| | |. ||.. |||. ..| |. ... .
YINAsfidgyr.krkayIAtqgPlaetiedFWRmvweqnsstiVmltkleEkgkvkchkYWPek..g..tetygeltVtleeeeeladyeirtfklkkkk
KSLCRPVTHYWFSNWLDSEIPSSPQALMSMLLQVHNTHQESYGPVVVHCSDGVGRTGLVIATDINMQRLEESHTVDIPHTVSSIRQDRGQAILNIDQYAF
.| | |... | .| |. .| |...|.... .|...... ||.||||| |||||| |. |. ..|..|..|||| .|. .|..| . . .||.|
ssesreVrqFhFtsWPdhgvpesatslLdlirkvralnepdagPivVhCSaGVGRTGtfividamlerikeektvDiyqyvkalrkqRnamVqteeQYiF
IYRTLYEFSKFL
|.....|. ..
iheailealacg
|
|||||||||
subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 727-933 | 6.4e-42 | 138.8 | In-house | 86-289 (298) | alignment | ||
Range on Protein: 727-933
Range on HMM: 86-289/298.0
FLDASFIRGYDSSHcSYIGATVSGGDSSTAFWRTVWEQQSRTIVCLCSPYELGK-VCPQYWPTKeggpGTQLYGNILVTLKGGASGEHYFTSTLLIRNVE
.. |||. .|. .. ..| . . . ||| |.|... ||| | . ||.| ...|||.. |.. ||.| |.|. . . . .| . . .
YiNAsflhaykgrn.afiatqaPltetvedFWrmvteedigtiVmltnleeldktkyhkywPde....gketygeitvsllskeefadlivrklkvskkk
KSLCRPVTHYWFSNWLDSEIPSSPQALMSMLLQVHNtHQESYG--PVVVHCSDGVGRTGLVIATDINMQRLEESHTVDIPHTVSSIRQDRGQAILNIDQY
.. | | . |..| | .|. .... .| .|. .|. | ||.|.||.||||.| || | ..|......||. ..| .|..| .|. .||
eekerevrqlhftsWpdkgvpenatsvldllrkvra.sqqqagnkpvivqCsaGvgRsGtfiaidsvlervkkeqvvDvfqvvkvlRkkrpgavqteeqY
AFIYRTLYEF
.||| |.
vfiyeavlea
|
|||||||||
subfamily_PTPN13_pd | Subfamily PTPN13 | 727-932 | 2.8e-36 | 120.2 | In-house | 62-267 (273) | alignment | ||
Range on Protein: 727-932
Range on HMM: 62-267/273.0
FLDASFIRG-YDSSHCSYIGATVSGGDSSTAFWRTVWEQQSRTIVCLCSPYELGKV-CPQYWPTKEGGPgTQLYGNILVTLKGGASGEHYFTSTLLIRNV
...||.|. . . .|| . .. . ||. ||||... |. . . | ||| | .||| ... . ..... . |.| . . . ..| ....
yinaslikvpvgkdeyeyiacqGPlPetvkdfwqmvweqkaeviamvtlekekgkvkchrywPesknkk.lkvsnrlevellkvqkldgfvvralavkds
EKSLCRPVTHYWFSNWLDSEIPSSPQALMSMLLQVHNTHQeSYGPVVVHCSDGVGRTGLVIATDINMQRLEESHTVDIPHTVSSIRQDRGQAILNIDQYA
| . | |.| | .| | ..|||.. |. .. .| . .. . ||.||||| |.||.| .|. |. .. .| . .|. ..| ..|. | . |||
esgesrevahlnfvkwPdhgvPssaaellqfvaevrrlqt.dagPivvhcsaGiGrsGtlitidvvlglierdkefdvkeivrklreqrqgvvqtkdqyi
FIYRTLYE
|.|... |
fvykaile
|
|||||||||
subfamily_PTPN14_pd | Subfamily PTPN14 | 727-933 | 2.2e-35 | 117.1 | In-house | 78-295 (300) | alignment | ||
Range on Protein: 727-933
Range on HMM: 78-295/300.0
FLDASFIRG-YDSSHCSYIGATVSGGDSSTAFWRTVWEQQSRTIVCLCSPYELGKV-CPQYWPTKEGGPGTQLYGNILVTLKGGASGEHYFTSTLLIRNV
...|| |. ... ||| | . ||. ||||. . || | . | || . .|.| .| | .|. || | . . . |..| .. .
yinassikvsvggkersyivaqgPleltvqdfWqmvWeqgvqlivmlteeeedgkeksfkyfPkleskkktvefgkfkvttkfsedsdsvittglklkhl
EKSLCRPVTHYWFSNWLDSEIPSSPQALMSMLLQVHNTH---------QESYGPVVVHCSDGVGRTGLVIATDINMQRLEESHTVDIPHTVSSIRQDRGQ
. | | | . .| | ..|. .. .| | .|. .|| ||.||||.|||||| .| .|. .. || ...||..... .|. |
pskeertvwhlqytDWpdhgvPeDvkgflsyLeevqsvrrktnseveskeskPPvlvhCsaGvGrtGvlilsdlliatlehneeidikkvlarLreqrml
AILNIDQYAFIYRTLYEF
. .. || |.|..| ..
lvqtlaqYkfvYkvliky
|
|||||||||
subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 727-932 | 3.9e-30 | 99.8 | In-house | 31-237 (237) | alignment | ||
Range on Protein: 727-932
Range on HMM: 31-237/237.0
FLDASFIRGYDSSHCSYIGATVSGGDSSTAFWRTVWEQQSRTIVCLCSPYELGK-VCPQYWPTKEGgPgtQLYGNILVTLKGGASGEHYFTSTLLI-RNV
...|....|.| . .|| | | ||. ||... || | | . | .||| . | . || . |.|| | .||. ...
yinatylkgfdgtpkkyiaaqgplesscddfwqmvwqekcsvivmltgliegnelkchkywpstdq.p..aaygvltvslkkkeefsdytvrslllskrl
EKSLCRPVTHYWFSNWLDSEIPSSPQALMSMLLQVHNT--HQESYGPVVVHCSDGVGRTGLVIATDINMQRLEESHTVDIPHTVSSIRQDRGQAILNIDQ
.. | . | |. | | .| ||. . .. | | || ..||| ||||||... | ... .| . ||| | || .|| | ||
tlkevrlihqyqftswpdrgvpqqtaallrfrkniinrsphvsesgpwiihcsagvgrtgiflvidamlrqakekkvvdiynyvysieedrpyiiqtkdq
YAFIYRTLYE
| ||..|. |
yvfihqtile
|
|||||||||
0043147 | (Phosphotyrosine protein) phosphatases II | 727-927 | 1.8e-27 | 91.5 | In-house | 7-154 (172) | alignment | ||
Range on Protein: 727-927
Range on HMM: 7-154/172.0
FLDASFIRGYDsSHCSYIGATVSGGDSSTAFWRTVWEQQSRTIVCLCSPyelgkvcpqywptkeggpgtqlygnilvtlkggasgehyftstlliRNVEK
. .||.. .| ...| .. ||| ..|.. ..||.|.. . .
yinasyldlyy.ipdrfiatqgplrntladfwrmlkelgithivnltel..............................................lydpe
SLCRPVTHYWFSNWLDSEIPsSPQALMSMLLQVHN-THQESYGPVVVHCSDGVGRTGLVIATDINMqrleesHTVDIPHTVSSIRQDRGQAILNIDQYAF
|.| . .|.. .| | | ... |...| .... .... |||.|||| ||||||...| .. . . ... ..|. .|. |..|. | .|| |
llerlgiqylylpwpDhgvp.llellleflefidellalspggpvlVHCsaGvgRtgtlvaaylml......lglsleeavalvrekRpgavqnpsqyrf
IY
.|
ly
|
|||||||||
subfamily_Sponge-PTP9_pd | Subfamily Sponge-PTP9 | 727-933 | 1.2e-23 | 78.3 | In-house | 72-292 (301) | alignment | ||
Range on Protein: 727-933
Range on HMM: 72-292/301.0
FLDASFIRGYDSSHcSYIGATVSGGDSSTAFWRTVWEQQSRTIVCLCSPYELGK-VCPQYWPTKEGGpgTQLYGNILVTLKGG-----------------
...||.| || ... .| | . ||| .|... .|| .. | | | ||||. | .. .|.. |||.
yinasyidgysekk.kfiaaqgpmkktlvdfWrliwqekpvsivmvtnlkegtkskceqywpnseae..seefgpftvtlvneqvyPdfvirqlnvkiqd
ASGEHYFTSTLLIRNVEksLCRPVTHYWFSNWLDSEI-PSSPQALMSMLLQVHNTHQESYGPVVVHCSDGVGRTGLVIATDINMQRLEESHTVDIPHTVS
.|.. |. ... ... . |. . .| . . . |... ..| ... . |||||||||.|.|.| .. .| . ||. .
gsnngyierkfkvksdk..sswdvlqlqvtdWpqdGvvreprtvLqviddvihrqqkigggpvvVHCSdtVsrsGvYcsvsiglEQckaegVVdvfqvtk
SIRQDRGQAILNIDQYAFIYRTLYEF
..|. . |. ..|| .|| . ..
avrrskpgaVtTLeqytsiydvidmy
|
|||||||||
subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 727-933 | 1.4e-21 | 71.5 | In-house | 67-276 (287) | alignment | ||
Range on Protein: 727-933
Range on HMM: 67-276/287.0
FLDASFIRGYDSSHcSYIGATVSGGDSSTAFWRTVWEQQSRTIVCLCSPYELGKV-CPQYWPTKeGGPgTQLYGNILVTLKGGASGEHYFTSTLLIRNVE
...| .. .| . ..| | . ||| |.|..| ... . | .. | .||| . | .. | .| |. .| . .| . ..|
yinanyvasytdde.afiaaqgPiaatvrdfwravletrsasvitmtreveearlkcykywPer.evP.mrvGGysvvlldydikePeygvralrlidle
KSLCRPVTHYWFSNWLDSEIPSSPQALMSMLLQV--H---NTHQESYGPVVVHCSDGVGRTGLVIATDINMQRLEESHTVDIPHTVSSIRQDRGQAILNI
.| | . . .| | .. . .|. . |.| | . . ||.|||.. |.||.|...|| . ..|||. ||. .| .|. | . .
trearvvkqldllswPdkvlaPtavglirfvldvkqhielardasevGPlvvhddvGiGrsGillatlvlvsrledlGrvdvaavvirlreyraalvqav
DQYAFIYRTLYEF
|. ..| .| .
vqlrllyealvty
|
|||||||||
subfamily_ptpA1_pd | Subfamily ptpA1 | 727-896 | 1.4e-15 | 52.0 | In-house | 77-258 (418) | alignment | ||
Range on Protein: 727-896
Range on HMM: 77-258/418.0
FLDASFIRGYDSshCSYIGATVSGGDSSTAFWRTVWEQQSRTIVCLCSPYELGKV-CPQYWPTKEGGPGTQLYGNILVtLKGGASGEHY-----FTSTLL
...| .| | .| . .. . ||| |||.. | || | | .. | .||| . || .||| . | | | ..
yinanyidgayp..kqfictqgplpntiadfwrmvwenrcriivmlsresencrikcdrywpeqiggeqfsiygngne.vfgtysvelveviqdpereii
IRNVE---KSLCRPVTHYWFSNWLDSEIPSSPQALMSMLLQVHNTHQ------ESYGPVVVHCSDGVGRTGLVIATDINMQRLEE
||. . | .|.| . | | .|| | . .| . | .. . |..|||| |||||| . .. | |..|.
trnirltfegetrditqyqyegwpdhnipdhtqpfrqllhsitnrqnqiipssdrnvpiivhcsagvgrtgtfctavimmkkldh
|
|||||||||
subfamily_Cele-PTP-15_pd | Subfamily Cele-PTP-15 | 727-933 | 2.8e-14 | 47.7 | In-house | 61-269 (285) | alignment | ||
Range on Protein: 727-933
Range on HMM: 61-269/285.0
FLDASFIRGYDSSHCSYIGATVSGGDSSTAFWRTVWEQQSRTIVCLCSPYELG-KVCPQYWPTKEGGPGT-QLYGNILVTLKGGASGEHYFtSTLLIRNV
.. ||..| . .|| . .. . ||. ..... .. ||. .| | . | |.| | | | | | | . .| . |
yihaswmrmpgkdqstyittqgplpetlsdfwhmiyqekiayvlmlctlfeggvekcalyypeklgevvkfgkyeitlteckeeaiagtil.naltvint
EKSLCRPV--THYWFSNWLDSEIPSSPQALMSMLLQVHNTHQeSYGPVVVHCSDGVGRTGLVIATDINMQRLEESHTVDIPHTVSSIRQDRGQAILNIDQ
| . |. | | | | . .. . |.. |..|||| ||||| .. | |. | ... | .| | ||. . |
edasseplymnhvqvpwwpdqlapedarpmielykwvkkvnp.kekpicvhcsagvgrtatfvgidyatirimenpniemldivremramrfqavqshmq
YAFIYRTLYEF
. |.| | |.
flflyvvlmey
|
|||||||||
0051082 | (Phosphotyrosine protein) phosphatases II | 728-932 | 4e-27 | 90.1 | In-house | 6-151 (151) | alignment | ||
Range on Protein: 728-932
Range on HMM: 6-151/151.0
LDASFIRGYdsshcSYIGATVsggdsSTAFWRTVWEQQSRTIVCLCSPYELGkVCPQYWPTKEggpgtqlygnilvtlkggasgehyftstllirnveks
...|.. |. |... . .|.....|.. .|||.|.|..| | ||.|.| .
infsyvtgg.....lyrsggp.....ladflellkelgiktivnlrseeerg.ycpeylpelg.....................................
lcRPVTHYWFSNWLDSEIPSSPQALMSMLLQVHNthqESYGPVVVHCSDGVGRTGLVIATDINMQRleeshtVDIPHTVSSIRQDRGQAILNIDQYAFIY
. |.|... .| | .| |..|....| .. . . |||.|||| |.||||...| .. ... |.. ... .|. |. .. .|. |..
..ievlhipildwpdpglplsfdavleflellld...kkngpvlvHCsaGkgRTGtlvalylmllg......vsleealeeyrlkrpgvvqpnqqflfql
RTLYE
. |.|
falle
|
|||||||||
subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 728-933 | 1.2e-24 | 81.5 | In-house | 84-282 (290) | alignment | ||
Range on Protein: 728-933
Range on HMM: 84-282/290.0
LDASFIRGYDSSHCSYIGATvsgGDSSTAFWRTVWEQQSRTIVCLCSPYELGKV-CPQYWPTKEGGPGTqlYGNILVTLKG-GASGEHYFTSTLLIRNVE
. | ...| .. ||. |. .|| | ... .|| || | || | ||.| ||| | .|.| |. .. || .|...
vhanyvkGlkamfiltqGal...kdtvidiwrmvlqekvaaivmlceliedGkakceqyypekeGevlt..fGeitvlcseeddkdaniikktlsvrdkd
KSLCRPVTHYWFSNWLDSEIPSSPQALMSMLLQVHNthqeSYGPVVVHCSDGVGRTGLVIATDINMQRLEESHTVDIPHTVSSIRQDRGQAILNIDQYAF
. . |. | | .. | ||. .| . . |||||||| |.|||| .| .. .| | . . .|. .| ..|. | ... ||
sGkehklkhlkikswpdksvalstlallrtlrilrk....asGpvvvhcsaGiGrtGtfvaievglqilldGkeldlldlvralrnsrlnsvqvdiqyla
IYRTLYEF
. . | ..
lveilldl
|
|||||||||
subfamily_Cele-PTP-10_pd | Subfamily Cele-PTP-10 | 729-933 | 4.2e-21 | 69.9 | In-house | 84-288 (305) | alignment | ||
Range on Protein: 729-933
Range on HMM: 84-288/305.0
DASFIRGYDSSHCSYIGATVSGGDSSTAFWRTVWEQQSRTIVCLCSPYELGKV-CPQYWPTKEGGPGTQLYGNILVTLKGGASGEHYFTSTLLIRNVEK-
| .. . .| | .. || | ... || || ||||. | ||||. | . | .. . | | . . |.
hanyvgcpmipekrficaqgpldqtidefwwmviqnkveqivmlcktvelgklkcaqywpaaqgeklelksgivvenvsgskpmerdaeiqitllnltys
-SLCRPVTHYWFSNWLDSEIPssPQALMSmlLQVHNTHQESYGPVVVHCSDGVGRTGLVIATDINMQRLEESHT-VDIPHTVSSIRQDRGQAILNIDQYA
. | | ...| | .| | | | |.. . . | |.||||| |.|||| ..| . .... | . .|. | ..|..| .| | ||
gdqkmsvrhlqwtewpdrgvp..pcklts..lellsairgskvpivvhcsagigrtgtivaieyilekiaenkpcppmpelvkalrdqrafsiqndvqyl
FIYRTLYEF
||.| . ..
fihrvmlny
|
|||||||||
0036282 | (Phosphotyrosine protein) phosphatases II | 730-928 | 5.4e-33 | 109.5 | In-house | 7-164 (174) | alignment | ||
Range on Protein: 730-928
Range on HMM: 7-164/174.0
ASFIRGYDSSHCSYIGATVSGgdsstaFWRTVWEQQSRTIVCLCSPYELG-KVCPQYWPTkeggpgtqlygnilvtlkggasgehyftstllirnVEKSL
||.. .. . ..|. ||. ..|....|.|.|....||| |..|||. ..|
aspldlsyitprliagqgpla......fwemlkelgittvvmlleekelglykcinywpe...................................lredl
CRPVTHYWFSNWLDSEIPSSPQaLMSMLLQVHNTHQE-SYGPVVVHCSDGVGRTGLVIATDINMQRLEeSHTVDIPHTVSSIRQDRGQAILNIDQYAFIY
| . .|.. .| | . |.... | ... .|.. ..| . |||.|||| ||||||...| .. ...|. . .||. ..| ..|. |.... . .|| |.|
erlgiqylylpwpDhgvpdlsi.llefvkfveealsedpggpvlVHCsaGvgRtGtlvaaylmlrgll.eslvdaldlvrelRlqrpgmvqtpsQyrfly
R
y
|
|||||||||
0041856 | (Phosphotyrosine protein) phosphatases II | 730-935 | 6.5e-30 | 99.5 | In-house | 24-172 (182) | alignment | ||
Range on Protein: 730-935
Range on HMM: 24-172/182.0
ASFIRGYDSSHCsYIGATVSGGDSSTAFWRTVWEQQSRTIVCLCspyelgkvCPQYWPtkeggpgtqlygnilvtlkggasgehyftstllirnveKSLC
|....|. . .| . . .. .|.|...|.. .|||.|. ...||| . |
anlylgslpatr.fiatqgpllstvadflrmlkelgittivnlt........eelywp......................................elle
RPVTHYWFSNWLDSEIPSsPQALMSMLLQVHNthqeSYGPVVVHCSDGVGRTGLVIATDINMQRleeshTVDIPHTVSSIRQDRGQAILNIDQYAFIYRT
| ...|.. .| | ..|. .. | ... .|.. . |||.|||| |||||| ..| .. ... |.....|. .|. | ... . .|| |...
rlgiqylylpwpDhgvpd.ldelldfieevle....eggpvlVHCsaGvgRtgtlvaaylmkkl.....gvsleeavklvrsrRpgmvitpnqyfflqla
LYEFSK
|.|. .
llelll
|
|||||||||
subfamily_PTPN1_pd | Subfamily PTPN1 | 738-939 | 1.4e-30 | 101.0 | In-house | 68-276 (290) | alignment | ||
Range on Protein: 738-939
Range on HMM: 68-276/290.0
SSHCSYIGATVSGGDSSTAFWRTVWEQQSRTIVCLCSPYELGKV-CPQYWPTKEGGPGTQLY-GNILVTLKGGASGEHYFTSTLLIRNVEKSLCRPVTHY
. ||| . . . ||. ||||.|...| | | ... | ||||..| .| .. |.| . ..| ..| . |.. .| ..|.
eakrsyiltqGPlpntvdhfWqmvWeqkskavvmlnkvvekeqikcaqywPqgeeekellledtklkvkliseerksyytvrllelenlktqetreilhf
WFSNWLDSEIPSSPQALMSMLLQVHNTH--QESYGPVVVHCSDGVGRTGLVIATDINM---QRLEESHTVDIPHTVSSIRQDRGQAILNIDQYAFIYRTL
. | | .|.||.|....| .| .. .. .||.|.||| |.||.| .. | . .. .. .||| ... .|. | | || | | ..
hyttwpdfgvpespaaflkflfkvresGslssdvGpavihcsaGiGrsGtfclvdtclvliekkddlssvdikkvllelrkyrlGliqtadqlrfsylai
YEFSKFLSS
| .|.. .
leGakvikg
|
|||||||||
0051429 | (Phosphotyrosine protein) phosphatases II | 741-936 | 6.7e-33 | 109.9 | In-house | 9-227 (272) | alignment | ||
Range on Protein: 741-936
Range on HMM: 9-227/272.0
CSYIGAT-------------VSGGDSSTAFWRTvWEQQSRTIVCLCSPYELGKVC-PQYWP--------TKEGGPGTQLYGNILVTLKGGASGEHYFTST
...| . ||| .|.. .|||.|.|..|.|.. ..||| . . .. | |||.. ||| ..| .
ardvggygrvvkpgrlyrsggplpltaadfwrl.kelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseellldyilre
LLIRNV-EKSLCRPVTHYWFSNWLDSEIPSSPqaLMSMLLQVHNthqesYGPVVVHCSDGVGRTGLVIATDINMQRLEESHTVD--------IPHTVSSI
||.... . | |.|... .|.| .|... | ..| .... |||.|||| |..|||.|.| .. ....... || . ..|. .
llltlllsagearevmhlhytdwpdhgvpqea..llellellld.....ggpvlvHCsaGkdRTGtvvallllllgvsletivddYlltnlyleeaveel
RQDRGQAILNIDQYAFIYRTLYEFSKF
|. | .|. . .||.|.|. | |. .
raqrpgavqteeqylflyeallellrs
|
|||||||||
subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 741-855 | 3.5e-07 | 24.4 | In-house | 76-189 (297) | alignment | ||
Range on Protein: 741-855
Range on HMM: 76-189/297.0
CSYIGATVSGGDSSTAFWRTVWEQQSRTIVCLCSPYELGK-VCPQYWPTKEGGpgTQLYGNILVTLKGGASGEhYFTSTL-LIRNVEKSLCRPVTHYWFS
|| | .. ||. |.||. |.|| .. | |. | ||| ... . |...| | | . . | .. . .| | |.| |
lkyilaqGplsatvddfwtlvaeqdvrvivmvaklqedGrdkcapywpsvvqe..rlkagdvvveflsstsde.fdrviltelqliyrsesrvvrhvqfl
NWLDSEIPSSPQALMSM
.| | .|| . | .
swpdhGvpsdledlvrf
|
|||||||||
subfamily_PTPN3_pd | Subfamily PTPN3 | 743-930 | 2.1e-36 | 120.3 | In-house | 86-271 (280) | alignment | ||
Range on Protein: 743-930
Range on HMM: 86-271/280.0
YIGATVSGGDSSTAFWRTVWEQQSRTIVCLCSPYELGKV-CPQYWPTKEggpGTQLYGNILVTLKGGASGEHYFTSTLLIRNVEKSLCRPVTHYWFSNWL
|| . ...| ||. ||||.|..|| | . | |.| | ||||..| .. ||.. |... .. . | . |.... |.. |.... . .|
yiatqGPlaktatdfWqmvweqksslivmlttlverGrvkChqyWPete...deleygefsvkcekedetksyvlrelvlkdketkeerkilqlqylaWp
DSEIPSSPQALMSMLLQVHNTHQESYGPVVVHCSDGVGRTGLVIATDINMQRLEESHTVDIPHTVSSIRQDRGQAILNIDQYAFIYRTL
|...|.... ..... .|..... . ||||||| |.||||..|. .. .. .|... | ... |. .|. |. . . .|| |. ..
dhgvPddsadflefvervrklrsgkeePvvvhCsaGigrtGvlilletalalieaaepvypldivrtmrdqramlvqtasqykfvCeai
|
|||||||||
0046846 | (Phosphotyrosine protein) phosphatases II | 743-933 | 2.1e-30 | 101.2 | In-house | 14-172 (176) | alignment | ||
Range on Protein: 743-933
Range on HMM: 14-172/176.0
YIGATVSGGD-----------SSTAFWRTVWEQQSRTIVCLCSPYELGKV-CPQYWPTKEGGPGtqlygnilvtlkggasgehyftstllirnvekslcr
|| | . |. . .|.. ..|.. ...|.|....|||.. ||.||| |.
yinanlilgsrpiatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpeleklgi....................................
pvtHYWFSNWLDSEIPSSpQALMSMLLQVHNTHQESyGPVVVHCSDGVGRTGLVIATDinmqRLEESHTVDIPHTVSSIRQDRG-QAILNIDQYAFIYRT
.|.. .| | .|.. ..|...| .... .| |||.|||| |.||||...| . || .. ... .... .|. | .|. . .|| |.|.
...qylhlpwpDhgvpdl.elllellefirealkeg.gpvlVHCsaGigRtgtlvaay....llelekglsveealalvreqRplgavqtpeQyrflyef
LYEF
....
elll
|
|||||||||
0049260 | (Phosphotyrosine protein) phosphatases II | 743-927 | 5.2e-29 | 96.3 | In-house | 11-143 (152) | alignment | ||
Range on Protein: 743-927
Range on HMM: 11-143/152.0
YIGATVSGGDSSTAFWRTVWEQQSRTIVCLCSPYELGKV-CPQYWptkeggpgtqlygnilvtlkggasgehyftstllirnvekslcrpvtHYWFSNWL
.|.. |. . ||| ..|.. .|||.|....||||. |.||. .| . .|
fiatqgpgpntladfwrmlkelgittivmltellelgklkceqyi...............................................qylhlpwp
DSEIPSSPQALMSMLLQVHNTHQESYGPVVVHCSDGVGRTGLVIATDINMqrleesHTVDIPHTVSSIRQDRGQAILNIDQYAFIY
|. |...| |. .|| .. ... |||.|||| ||||||...| .. . . |.. ..|. .|. | .|. | .|. |.|
DhgvpdlsqlllflllfieklaldkggpvlVHCsaGvgRtgtlvaaylml......lgvsleeavalvrekRpgavpnpgqlrfly
|
|||||||||
subfamily_Anemone-PTP-3_pd | Subfamily Anemone-PTP-3 | 743-928 | 1.1e-22 | 75.2 | In-house | 7-198 (199) | alignment | ||
Range on Protein: 743-928
Range on HMM: 7-198/199.0
YIGATVSGGDSSTAFWRTVWEQQSRTIVCLCSPYELGK-VCPQYWPTKEGGpgTQLYGNILVTLKGGASGEHYFTSTLLIRNVE--KSLCRPVTHYWFSN
|| . . .. . ||. ||| | || . . | |||| | | | ||.. || | .. | ..|.. | | ..|| |.
yiatqhplretmadfwqmvwetgsghivmvnddqknkeadypfywpttesg..tgkygslsvttktittkpdytitaliltnnttappstreishyqfts
WLDSEIPSSPQALMSML--LQV-HNTHQESYGPVVVHCSDGVGRTGLVIATDINMQRLEESHT--VDIPHTVSSIRQDRGQAILNIDQYAFIYR
| . | . .. .| .. || ||.|||||| | ||. .| || .. |||.| ||. .|| | | ...| |||.
wkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiisslqhynfiyq
|
|||||||||
subfamily_Nvec-PTP-3_pd | Subfamily Nvec-PTP-3 | 743-928 | 1.1e-22 | 75.2 | In-house | 6-197 (198) | alignment | ||
Range on Protein: 743-928
Range on HMM: 6-197/198.0
YIGATVSGGDSSTAFWRTVWEQQSRTIVCLCSPYELGK-VCPQYWPTKEGGpgTQLYGNILVTLKGGASGEHYFTSTLLIRNVE--KSLCRPVTHYWFSN
|| . . .. . ||. ||| | || . . | |||| | | | ||.. || | .. | ..|.. | | ..|| |.
yiatqhplretladfwqmvwetgsghivmvnddqknkeadypfywpttesg..tgkygslsvttktittkpdytitaliltnnttappstreishyqfts
WLDSEIPSSPQALMSML--LQV-HNTHQESYGPVVVHCSDGVGRTGLVIATDINMQRLEESHT--VDIPHTVSSIRQDRGQAILNIDQYAFIYR
| . | . .. .| .. || ||.|||||| | ||. .| || .. |||.| ||. .|| | | ...| |||.
wkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiisslqhynfiyq
|
|||||||||
subfamily_Cele-PTP-6_pd | Subfamily Cele-PTP-6 | 743-933 | 5.2e-22 | 73.2 | In-house | 84-276 (307) | alignment | ||
Range on Protein: 743-933
Range on HMM: 84-276/307.0
YIGATVSGGDSSTAFWRTVWEQQSRTIVCLCSPYELGKV-CPQYWPTKEGGPGTqlYGNILVTLK---GG----ASGEHYFTSTLlIRNVEKSLCRPVTH
.| | .. || . ... ... || ||.|. | |||| .|| . .|. |. | | |.. | .. . . .| ..|
ficaqgplentqysfwamaiqekvesvimlckvielakikceqywpleegqklv..fgeapntisvanlgakklapdedlinvtt.lkvdwaqksrtiqh
YWFSNWLDSEIPSSPQALMSMLlQVHNTHQesyGPVVVHCSDGVGRTGLVIATDINMQRL-EESHTVDIPHTVSSIRQDRGQAILNIDQYAFIYRTLYEF
. ..|| | .| . . .| . . .. ||||||| ||||.| ..| . .... . |. . | .|..| || . || ...| | |.
lqwenwpdrgvpqinltainll.eavrydt...npvvvhcsaGvGrsGtivaislvqdkmiaGinckdmkklveelrsqrhyaiqteaqylylhrvlley
|
|||||||||
subfamily_Cele-PTP-18_pd | Subfamily Cele-PTP-18 | 743-934 | 2.9e-18 | 60.7 | In-house | 90-287 (305) | alignment | ||
Range on Protein: 743-934
Range on HMM: 90-287/305.0
YIGATVSGGDSSTAFWRTVWEQQSRTIVCLCSPYELG-KVCPQYWPTKEGGPGTQLYGNILVTLKGGASGEHYF--------TSTLLIRNVEKSLCRPVT
.| . .. . || .... .| || | | | | .|...|.. . .. ...| .|.. | | | |. . . | ||
fictqaplektcadfwymclqdkveaifmlcnllekgakkcleyfaskdkdvlefeekgqkisvkfessvtlkfrkdakakvtetvlviegpgekarkvt
HYWFSNWLDSEIPSSPQALMSMLLQVhnthQESYGPVVVHCSDGVGRTGLVIATDINMQRLEESHTVD-IPHTVSSIRQDRGQAILNIDQYAFIYRTLYE
|| . .| | .|.. .|.. .| . . | ||.||||| |.|||| |. . ...| . . .. . . ||..| ..| .|| |... . .
hyhwidwpdrgvpaadlailelleka....rpskgpivvhcsagigrtgsvvmleyildqllagqiiedtdkilqkireqrnnsiqtdaqylfvhqviln
FS
.
yf
|
|||||||||
subfamily_Cele-PTP-11_pd | Subfamily Cele-PTP-11 | 751-949 | 3.2e-11 | 37.5 | In-house | 92-288 (312) | alignment | ||
Range on Protein: 751-949
Range on HMM: 92-288/312.0
GDSSTAFWRTVWEQQSRTIVCLCSPYELGK-VCPQYWPTKEGG---PGTQLYGNILVTLKGGASGEHYFTSTLLiRNVEKSLC--RPVTHYWFSNWLDSE
...| ||. . | .|. ||. | | | .| | ..| . .. | | .| . | |. . || .. | |
entcthfwqlalslgstsiillcgfvedgsekcakyisdivgfvdledhrvyteycteieiggkskdkithrvl.kvvvkatgqesklnhyqwaswpdhg
IPSSPQALMSMLLQVHNTHQesygPVVVHCSDGVGRTGLVIATDINMQRLEESHTVDIPHTVSSIRQDRGQAILNIDQYAFIYRTLYEFskfLSSSGTKE
.| | .. . .| |.. .. ||. ||| |||||| .. . . | .. .. .|.|| ... . || . |.. || | | | .
mpdscdtalrllsavkkdkk....pviahcsagvgrtgtlaliesmiaalrhprkqnvkdsfvllrkdrarsvrvfpqyvyalrcvlef...lyskglyk
TSDTE
.. |
rneqe
|
|||||||||
subfamily_Cele-PTP-4_pd | Subfamily Cele-PTP-4 | 753-935 | 3.3e-19 | 63.4 | In-house | 105-286 (302) | alignment | ||
Range on Protein: 753-935
Range on HMM: 105-286/302.0
SSTAFWRTVWEQQSRTIVCLCSPYELGKVCPQYWPTKEGGpgTQLYGNILVTLKGGA--SGEH-YFTSTLLIRNVEKSLCRPVTHywFSNWLDSEIPSSP
| ||| |.... ..| | . || | ...|.| | . ||.. | . ..|. .. .| .. |. |.. ..|| ....| .
sveeFWrmvfqekivsvvilvgeeelkktlselfpkksgd..ykeygkmfvNnrkVekaeeektryviEvlPegcsnsvlanvyv..ltnWkqkkvpvky
QALMSMLLQVHNTHQESYGPVVVHCSDGVGRTGLVIATDINMQRLEESHTVDIPHTVSSIRQDRGQAILNIDQYAFIYRTLYEFSK
.|. .|.. .... ..|. |.|| | ... . ...|.... . | .| |||..| .|. ...||...|..| . |
aeliktaakvfakkikadentvivSknGaGRagafltlavaveklqkgkepnikeivksiRsqRpravdslkQyvslyialllyik
|
|||||||||
subfamily_Cele-PTP-19_pd | Subfamily Cele-PTP-19 | 753-932 | 4.7e-16 | 53.4 | In-house | 102-280 (301) | alignment | ||
Range on Protein: 753-932
Range on HMM: 102-280/301.0
SSTAFWRTVWEQQSRTIVCLCSPYE-LGKVCPQYWPTKEGGPGTQLYGNILVTLKGGASGEHYFTSTLLIRNVEKSL-CRPVTHYWFSNWLDSEIPSSPQ
.| || . . .|| |. | | ..| .| |.| . .| .. | .. || ... . . | |||| .|.| | ..| |
tsedfwamlvqydvekivmlgqkvekleekceeylpvkisekldigrfkikiknkelilnkkiskrtlevedstgkfatrtvthyqysewtdrgvPksha
ALMSMLlqvhNTHQESYGPVVVHCSDGVGRTGLVIATDINMQRLEESHTVDIPHTVSSIRQDRGQAILNIDQY-AFIYRTLYE
|. .. . ..| |.|||||.|.||. |.|.. ...| |... ... .|..| ... . | |.|
elfdlm....elvkksekPivvhcsaGiGrsvafigteylareveadptieltealkhlrehrwngvqtnsqlywmtlGtvyr
|
|||||||||
subfamily_Cele-PTP-9_pd | Subfamily Cele-PTP-9 | 755-933 | 5.7e-17 | 56.6 | In-house | 42-220 (255) | alignment | ||
Range on Protein: 755-933
Range on HMM: 42-220/255.0
TAFWRTVWEQQSRTIVCLCSPYELGKV-CPQYWPTKEGgpGTQLYGNILVTLKGGASGEHYFTSTLLIRNVEKSLCRPVTHYWFSNWLDSEIPSSPQALM
.|..|. ... ..| || .| |.. | .|.|.. . . . .. || .. | ... || . |.|| . |.. | .. ..
dkfyqtivqtktevvvmlcdfaeegvekcssyfplekd..eklkladvnvtttkssadvvlrtleitstlgekkkthtvkhysykGWieknaPelareil
SMLLQVHNthqeSyGPVVVHCSDGVGRTGLVIATDINMQ----RLEESHTVDIPH--TVSSIRQDRGQAILNIDQYAFIYRTLYEF
.| |.. | .|||||| |.||. . ... | |....||.. . . .|. | .|| . | || .. ..
nilkvvrd....s.ksvvvhCstGiGrsaafvlaelvyqkmirsldttetveldylslleelrskrkraihtPlqlafsilmvldl
|
|||||||||
subfamily_Cele-PTP-1_pd | Subfamily Cele-PTP-1 | 756-928 | 2e-17 | 58.3 | In-house | 82-253 (290) | alignment | ||
Range on Protein: 756-928
Range on HMM: 82-253/290.0
AFWRTVWEQQSRTIVCLCSPYELGK-----VCPQYWPTKEGGpgTQLYGNILVTLKGGASGEHYFTSTLLIRnVEKSLCRPVTHYWFSNWLDSEIPSSPQ
|| .. . ... .| || | . | .| |...|. .... | | . | .|... .. |||.....| ..... ...
kfwwmakqEkvkqvVmlcefeeksantslfaCakYvpesvge..elkfkgltvkCkskekeddvetRelvvk.fddeeeftvtHsllkgWnklnvqedtk
ALMSMLLQVHnthqESYGPVVVHCSDGVGRTGLVIATDINMQRLE-ESHTVDIPHTVSSIRQDRGQAILNIDQYAFIYR
|.|.. .|. | ||.||| ||. | . | .. .| . |. | . ....|. | .|| . ..||.
tllsliqkvk....asktpvivHcvdGiSrsAalaaiilgyQkiaetsgsvkledvlkalrkqralaitsalelafvda
|
|||||||||
subfamily_Cele-PTP-8_pd | Subfamily Cele-PTP-8 | 756-932 | 2.1e-17 | 58.1 | In-house | 97-269 (288) | alignment | ||
Range on Protein: 756-932
Range on HMM: 97-269/288.0
AFWRTVWEQQSRTIVCLCSPYELGKVCP-QYWPTKEGgPGTQLYGNILVTLKGGASGEHYFTSTLlIRNVEKSLCR-PVTHYWFSNWLDSEIPSSPQALM
.|. . |.. . || || |.|| .|.|.| | ... . |. | | .. . .| .|. .. . | . . .| | .| . .. .
elWkmllesdveyivmlcellekGkeksaeyfPsklG.ekarigrlctvvkkkradidklvkvsl.lriskegeekvivkilhlleWdddgvPenylspl
SMLLQVHNTHQesygPVVVHCSDGVGRTGLVIATDINMQRLEESHTVDIPHTVSSIRQDRGQAILNIDQYAFIYRTLYE
.| ...... |.|||.| |||||| .| . | .. | . . |.. ... |..| .|| || ...| ..|
rllevlkslqk....PivvhssaGvGrtgtlililialeslrlddflgirsllaklreerfkaiqtemqylyvhrcvle
|
|||||||||
subfamily_hpo-7_pd | Subfamily hpo-7 | 756-933 | 8e-14 | 46.2 | In-house | 49-226 (263) | alignment | ||
Range on Protein: 756-933
Range on HMM: 49-226/263.0
AFWRTVWEQQSRTIVCLCSPYELGKV-CPQYWPTKEGgpGTQLYGNILVTLKGGASgEHYFTSTLLIRNVE-KSLCRPVTHYWFSNWLDSEIPSSPQALM
.|..|. ... ..| || .| |.. | .|.|.. . | . |. |. | . . |. ... | . |.|| . |.. . | .. .
kfyqtivqtktevvvmLcDfneegvekcssyfPlekd..ekqklanvnvcttkvqs.dvllktlellstlgeKkkthtvkhysykgWiekndpelareil
SMLLQVhnthQESyGPVVVHCSDGVGRTGLVIATDINMQ----RLEESHTVDIPH--TVSSIRQDRGQAILNIDQYAFIYRTLYEF
.| . ..| ..||||| |.||. ... | |....||.. . . .|. | .|| . | || .. .|
nilkva....rns.kslvvhcstGiGrsaafsvaElvyqkmirsldttstveldylsLleelrssrkraihtPmqLafsilmvLdf
|
|||||||||
subfamily_Cele-PTP-14_pd | Subfamily Cele-PTP-14 | 756-935 | 2.2e-13 | 44.5 | In-house | 109-291 (310) | alignment | ||
Range on Protein: 756-935
Range on HMM: 109-291/310.0
AFWRTVWEQQSRTIVCLCSPYELGKV-CPQYWPTKeGgpGTQLYGNILVTLKGGASGEHYF---TSTLLIRNVEKS-----L-CRPVTHYWFSNWLDSEI
||| ...... .|. || | |. | |||. | |. || | || . .| | . |.. || | |. . || | .
dfwrmifqeraesilllckvgeegrpkcvgywpsl.g..vtetygcirvtnlsesseefeicnlavtfvpdnvpvdeqpanlkelrvslikwpnwpdrgv
PSSPQALMSMLLQvhntHQESYGPVVVHCSDGVGRTGLVIATDINMQRLEESHTVDIPHTVSSIRQDRGQAILNIDQYAFIYRTLYEFSK
| . | | .||.||||| |..|...|.| ......|.. . ||. . .. ....| . | . || .| | |..
pdekchtvpqrll....aqvrhgpcvvhcsagkdrlyvvvalklkidkldrglkvdaeevktellksraiciqtelqyliidrvriifar
|
|||||||||
0048179 | (Phosphotyrosine protein) phosphatases II | 763-928 | 6.4e-20 | 66.8 | In-house | 27-139 (144) | alignment | ||
Range on Protein: 763-928
Range on HMM: 27-139/144.0
EQQSRTIVCLCSPYELGKVCPQywptkeggpgtqlygnilvtlkggasgehyftstllirnvekslcrpVTHYWFSNWLDSEIPSSPQALMSMLLQVHNT
... .|...|...|| . .. ...|.. .| | ..|.... | ..| ...
klgittvinlteeyepeflere...............................................giqylhlpwpDhgvpdllellleflefieea
HQESyGPVVVHCSDGVGRTGLVIATDINMqrleeSHTVDIPHTVSSIRQDRGQAILNIDQYAFIYR
..|. |||.|||| ||||||...| .. . . ... ... .|. | .|. | .|. |...
leeg.gpvlVHCsaGvgRtgtlvaaylmk.....klglsleealalvrsrrpgavpnpgqlrfLle
|
|||||||||
0048076 | (Phosphotyrosine protein) phosphatases II | 796-930 | 1.9e-21 | 71.7 | In-house | 11-139 (145) | alignment | ||
Range on Protein: 796-930
Range on HMM: 11-139/145.0
QLYGNILVTLKGGASGEHYFTSTLLIRNVEKSLCRPVTHYWFSNWLDSEIPSSPQALMSMLLQVHNTHQESyGPVVVHCSDGVGRTGLVIATDINMQrle
.|.. ..|. .. .| | . . .. | | ...|.. .| | ..|.... |...| .... ..| |||.|||| ||||||...| .. ..
lylgslptaldlellkdlgittvlnltselellerlgiqylylpwpDhgvpdllellleflefieealkeg.gpvlVHCsaGvgRtgtlvaaylmll...
esHTVDIPHTVSSIRQDRGQAILNIDQYAFIYRTL
. |...... .|. | .|. | .|. |.|. .
..lgvsleealelvrsqrpgavpnpgqlrflyefe
|
|||||||||
subfamily_Cele-PTP-7_pd | Subfamily Cele-PTP-7 | 824-926 | 1e-09 | 32.3 | In-house | 182-280 (302) | alignment | ||
Range on Protein: 824-926
Range on HMM: 182-280/302.0
VEKSLCRPVTHYWFSNWLDSEIPSSPQALMSMLlQVHNTHQESygpVVVHCSDGVGRTGLVIATDINMQRLEESHTVDIPHTVSSIRQDRGQAILNIDQY
..| . ..| || | | | ... . .| . ...... |.|||| |||||| ..| .| . .. |. . | .|| | |. . .|
kkkkvkktvdilafsawpdhGapkeaytaldil.kfcesykkn...vlvhcsaGvGrtGtlvaikyGiqlcskkkvtdllsivlpvrqcryGavqdeqql
AFI
..
iyl
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 829-932 | 2.8e-15 | 50.6 | In-house | 88-192 (440) | alignment | ||
Range on Protein: 829-932
Range on HMM: 88-192/440.0
CRPVTHYWFSNWLDSEIPSSPQALMSMLLQVHNTHQ-ESYGPVVVHCSDGVGRTGLVIATDINMQRLEESHTVDIPHTVSSIRQDRGQAILNIDQYAFIY
.| . .| . | | .| .. |. .| .... . ||..|||| |.||||..|| | .. . | .|| ..|.|..| | . .||||..
srtlkqyhyqgwpdkgvpkfagpvlkmiqdvnesqekagngpllvhcsagagrtgviiavdsilreakrsdqidifsfinsmrnnrpqmvqtpeqyafvh
RTLYE
.. |
eavle
|
|||||||||
subfamily_PTPDC1_pd | Subfamily PTPDC1 | 831-938 | 7.4e-07 | 23.8 | In-house | 82-176 (182) | alignment | ||
Range on Protein: 831-938
Range on HMM: 82-176/182.0
PVTHYWFsNWLDSEIPSsPQALMSMLLQVHNTHQESygPVVVHCSDGVGRTGLVIATDINMqrleeSHTVDIPHTVSSIRQDRGQAILNIDQYafiyRTL
...| | | | . .| . .. . |. . || | ||| | ||||..||. . .. .. .... .|. | ..| .| ...
giyvynf.gwkDygvas.leriLdivkvvafalqeg..kvavhChaGlGrtGvliacylvy.....akrltaekaiklvrskrpksiqtreqv....elv
YEFSKFLS
||..||.
kefalfli
|
|||||||||
PTPc_DSPc_SM00012 | 832-931 | 6.5e-30 | 98.8 | In-house | 2-104 (105) | alignment | |||
Range on Protein: 832-931
Range on HMM: 2-104/105.0
VTHYWFSNWLDSEIPSSPQALMSMLLQVHNTHQESY--GPVVVHCSDGVGRTGLVIATDINMQRLEES-HTVDIPHTVSSIRQDRGQAILNIDQYAFIYR
|.||....| | ..|.........| .|.. ...|. .|||||||.|||||| ..| || .|.||.. ..||| .|...|. | ... . .|| |.||
vkhyhytgwpdhgvPeesdsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgmvqteeqylflyr
TLY
|
all
|
|||||||||
subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 832-932 | 1.1e-09 | 32.5 | In-house | 217-342 (350) | alignment | ||
Range on Protein: 832-932
Range on HMM: 217-342/350.0
VTHYWFSNWLDSEIPSSPQALMSMLL---------QVHNTHQ-ESYGPVVVHCSDGVGRTGLVIATDINMQ---R----LEESHTVD--------IPHTV
| . . ||.|. . |. ....| .. . . |..|||| |||||| ... | .. .||. .| | .|
vyqlqvknWkDlslllnPesilqalevkndliddlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaaktrDlisiiv
SSIRQDRGQAILNIDQYAFIYRTLYE
.|. | . . |.||. ||| .|
nelrkqrismvqnldqfifiYeallf
|
|||||||||
subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 839-933 | 6.5e-06 | 19.7 | In-house | 227-343 (349) | alignment | ||
Range on Protein: 839-933
Range on HMM: 227-343/349.0
NWLDSEIPSSPQALMSMLLqVH-----------NTHQESYGPVVVHCSDGVGRTGLVIATDINMQ--RLE--ESHTVD--------IPHTVSSIRQDRGQ
||||. . |.... | | ... ...|||| | |||| .. |. .. || .. | .| ..|. | .
nwldlslllnPisilqale.vkndliddlfarlyldtdqlstllvhcsaGcGrtGvlvtldlllsileplqnesnkiklqallkDlisiivnelrkqris
AILNIDQYAFIYRTLYEF
. |. |. .|| .| ..
mvqnlaqfiaiyealLky
|
|||||||||
0038934 | (Phosphotyrosine protein) phosphatases II | 841-929 | 1.1e-06 | 23.9 | In-house | 88-172 (194) | alignment | ||
Range on Protein: 841-929
Range on HMM: 88-172/194.0
LDSEIPSSPQALMSMLLQVHNTHQE-SYGPVVVHCSDGVGRTGLVIATDInmqrlEESHTVDIPHTVSSIRQDRGQAILNIDQYAFIYRT
| . | . |.. | |. ..| . | |.||| |.||||...| . ... . . .|. |. || |.|.. ...
pddgtvPsleillrfldlvdeflnedpggvvaVHCkaGlgRtGtlvaaYL.....iyrlgmsaeeAialfrekRpgaipnqdyleallkr
|
|||||||||
subfamily_CDKN3_pd | Subfamily CDKN3 | 842-937 | 3e-07 | 24.2 | In-house | 109-199 (202) | alignment | ||
Range on Protein: 842-937
Range on HMM: 109-199/202.0
DSEIPSsPQALMSMLLQVHnTHQESYGPVVVHCSDGVGRTGLVIATDINMqrLeeSHTVDIPHTVSSIRQDRG-QAILNIDQYAFIYRTLYEFSKFL
| .|. . . . .| ... . ..| .||| |.||. |||| . . | . |.. ......|. .| .|| . || .. ...|
dglvpd.iasclkileelr.inlkayrktlvhcygglgrsslviacllly..l..ddtiepkdaidklrdlkgsraiqtvkqynylsefrdkleeyl
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 862-937 | 7.5e-41 | 134.8 | In-house | 242-318 (319) | alignment | ||
Range on Protein: 862-937
Range on HMM: 242-318/319.0
THQESYGPVVVHCSDGVGRTGLVIATDINMQRLEES-HTVDIPHTVSSIRQDRGQAILNIDQYAFIYRTLYEFSKFL
..||.||.||||||||||||||||.||....|||| ..||||..|||.|.||..|.|...||.|||..|.|..|.|
gtresqGPlvvhcsdGvGrtGlviasdiairsleeskrsvdiPqlvssvrrdrasavltkeqyefiykvlseyakkl
|
|||||||||
subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 867-929 | 1.3e-10 | 35.6 | In-house | 228-290 (297) | alignment | ||
Range on Protein: 867-929
Range on HMM: 228-290/297.0
YGPVVVHCSDGVGRTGLVIATDINMQRLEESHTVDIPHTVSSIRQDRGQAILNIDQYAFIYRT
...|||| ||||.|.|. .|. ...| . |. .| .|. | . . ..|. ..|
nayllvhcsaGvGrsGvvvlsdvilaklrkkripdvaailsilreqrarlvqtleqfellyda
|
|||||||||
subfamily_Sponge-PTP-7_pd | Subfamily Sponge-PTP-7 | 871-933 | 3.5e-11 | 37.3 | In-house | 2-64 (69) | alignment | ||
Range on Protein: 871-933
Range on HMM: 2-64/69.0
VVHCSDGVGRTGLVIATDINMQRLEESHTVDIPHTVSSIRQDRGQAILNIDQYAFIYRTLYEF
||||| | |||| || ..| |. ||| | .|. | ..| .| ||. .| |
vvhcssgtgrtgtfiaimvemarikseklvdifnnvqymrkcrpmmvmneieyifihdalvea
|
|||||||||
subfamily_Sponge-PTP7_pd | Subfamily Sponge-PTP7 | 871-933 | 5.5e-11 | 36.7 | In-house | 1-63 (69) | alignment | ||
Range on Protein: 871-933
Range on HMM: 1-63/69.0
VVHCSDGVGRTGLVIATDINMQRLEESHTVDIPHTVSSIRQDRGQAILNIDQYAFIYRTLYEF
||||| | |||| || ..| |. ||| | .|. | ..| ..| ||. .| |
vvhcssGtGrtGtfiaimvemarikseklvdifnnvqymrkcrpmmvmneneymfihdalvea
|